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As far as MEWDS is concerned, OCT-A was useless, as end-capillary low flow circulation is not
identified by OCT-A. To declare that “posterior uveitis is also termed choroiditis” is a blatant
misconception. Therefore, it represented a valuable supplementary tool in the appraisal of posterior
uveitis. The most common HCVA charts employed in clinical research studies include the Snellen
and Early Treatment Diabetic Retinopathy Study (ETDRS) charts. After excluding case report
articles, 114 articles were retained: 4 in 2016, 17 in 2017, 14 in 2018, 21 in 2019, 14 in 2020, 18 in
2021 and 26 in 2022. Moreover, EDI-OCT, contrary to ICGA, can provide accurate three-
dimensional images of the choroidal layers with precise measurement of the depth and morphology
of the lesions. 1.4. Blue Light Fundus Autofluorescence (BAF) BAF is a valuable tool which is
becoming more and more frequently used in daily practice by ophthalmologists. It was useful for
follow-up in two cases of APMPPE, showing the evolution of choriocapillary drop-out without the
need to repeat ICGA ( Figure 3 ). This represented a considerable advantage over classical
“standardization of uveitis nomenclature (SUN)” that promoted merely qualitative and inadequate
vitreous haze estimation as the sole measurement of posterior uveitis. Motion Perception Testing:
Standard tests of visual function generally interrogate our perception of “form,” and tend to ignore
perception of motion, which has an enormous impact on the day-to-day function. Next Article in
Special Issue Retinal Vascular Tortuosity Index Change after Idiopathic Epiretinal Membrane
Surgery: Does Internal Limiting Membrane Peeling Affect Retinal Vascular Tortuosity. Interestingly,
in ON eyes lower MV values were associated with color vision loss. Herbort, C.P., Jr.; Takeuchi, M.;
Papasavvas, I.; Tugal-Tutkun, I.; Hedayatfar, A.; Usui, Y.; Ozdal, P.C.; Urzua, C.A. BAF can provide
information on the RPE and the outer retina, and in some cases, can replace the dye exams involved
in the follow-up of certain uveitis entities. Indeed, the patient developed a recurrence 2 years later
and the diagnosis was reverted to MFC. Cancel anytime. Ebook 503 pages 12 hours Optical
Coherence Tomography: Principles and Applications Show full title By Mark E. In the convalescent
phase, many ON patients report the “Pulfrich phenomenon” (a binocular perception that a small
target moving in a frontal plane is traveling in an elliptical path) and describe difficulties tracking
moving objects. In this review we reviewed the scientific literature regarding the application of OCT
in forensic science and legal medicine from 1995 to 2019. Nevertheless, OCT-A is a precious tool in
uveitis research. High-Contrast Visual Acuity: High-Contrast Visual Acuity (HCVA) refers to the
spatial resolving ability of the eye and has long been the mainstay of visual standard testing.
Subsequently, a new trend incorneal thinning was observed in association with the appearance ofone
or more demarcation lines between the anterior andposterior stroma. Three weeks later, after the
partial re-perfusion seen on ICGA ( bottom middle ), the damaged areas were visible on BAF (
bottom left ). Journal of Cardiovascular Development and Disease (JCDD). Optical Coherence
Tomography Angiography (OCT-A) in Uveitis: A Literature Review and a Reassessment of Its Real
Role. It does not require the injection of a dye in order to image the retina, but instead, it takes
advantage of the (auto)fluorescent properties of lipofuscin within the RPE to provide information on
pathologic changes in the fundus. References Novotny, H.R.; Alvis, D.L. A method of
photographing fluorescence in circulating blood in the human retina. Editors select a small number of
articles recently published in the journal that they believe will be particularly. FD-OCT devices
include a spectrometer in the receiver that analyzes the spectrum of reflected light on the retina or
ocular surface and transforms it into information about the depth of the structures according to the
Fourier principle. This patient was diagnosed and followed as MEWDS thanks to BAF. Hence, in
using OCT to differentiate ON associated with NMO from ON associated with MS, it is important
to be mindful of issues that could affect RNFL values in either group, including recurrent ON in the
same eye and bilateral optic nerve involvement. This approach stands out in a recent article by
multiple authors entitled “Experts opinion: OCTA vs.
The creation of specific 'ad hoc' devices and a better knowledge of this type of technology by
pathologists will be a fundamental step to continue to develop the use of OCT forensic fields. See
Full PDF Download PDF See Full PDF Download PDF Related Papers forensik Gresia Kristi
Download Free PDF View PDF Morphological analysis of corneal findings modifications after
death: A preliminary OCT study on an animal model Matteo Nioi The aim of this work was to
describe, for the first time, the morphological modifications, in a three-dimensional mode, of the
central cornea at different intervals since death. This approach stands out in a recent article by
multiple authors entitled “Experts opinion: OCTA vs. The authors considered the terms of uveitis
and choroiditis as equivalent. Perimetry has evolved through stages since original confrontation-
based techniques to allow quantification and statistical analysis in its currently used computerized
forms. This provides critical information about visual function, including both central and peripheral
channels. In practice, what is presently considered and suggested as the standard of care for the
assessment of retinal inflammation is a baseline FA and OCT. At this early stage of development, the
authors state that “none of the older imaging modalities can be replaced by OCT-A at present”. In
the convalescent phase, many ON patients report the “Pulfrich phenomenon” (a binocular perception
that a small target moving in a frontal plane is traveling in an elliptical path) and describe difficulties
tracking moving objects. Indeed, when promoting an instrument, it is commercially more interesting
to affix the label of routine everyday use rather than that of being predominantly an instrument of
research purposes. Optical Coherence Tomography Angiography (OCT-A) in Uveitis: A Literature
Review and a Reassessment of Its Real Role. European Journal of Investigation in Health,
Psychology and Education (EJIHPE). Since the 24th hour, the epithelium disappeared in 50% of
cases and the anterior chamberdepth progressively decreased. In this article, they also wrote “OCT-A
was not able to detect clear signs of active inflammation around the affected vessels”. Gout, Urate,
and Crystal Deposition Disease (GUCDD). OCT-A did not yield additional information, showing the
same non-perfusion areas as seen on ICGA (choriocapillary drop out), limited to the central macular
area, but was useful in the follow-up of these central damaged areas (also see Figure 3). (Far-right)
OCT-A images at presentation ( top right ) and after 3 weeks ( bottom right ). BAF is of comparable
value to ICGA to follow choriocapillaritis entities such as MEWDS or MFC. The articles gave
information either on retinal circulation, choroidal circulation or both. Three weeks later, after the
partial re-perfusion seen on ICGA ( bottom middle ), the damaged areas were visible on BAF (
bottom left ). We found that 4 articles were published in 2016, 17 in 2017, 14 in 2018, 21 in 2019, 14
in 2020, 18 in 2021 and 26 before the end of August 2022. In the setting of acute ON, HCVA
impairment is generally maximal at onset, and the deficit in HCVA at one month can predict long-
term recovery. This represented a considerable advantage over classical “standardization of uveitis
nomenclature (SUN)” that promoted merely qualitative and inadequate vitreous haze estimation as
the sole measurement of posterior uveitis. Additionally, a single ICGA time frame was used for
comparison to OCT-A. Not surprisingly, RNFL atrophy tends to be extensive in ON eyes of patients
with NMO. As for other modalities, it is hampered by artifacts from media opacities such as
cataracts or vitreous opacities, making the interpretation of images in some patients difficult.
Hyperautofluorescence can indicate damage to the RPE cells unable to eliminate fluorophores that
accumulate unduly. Editor’s Choice articles are based on recommendations by the scientific editors
of MDPI journals from around the world. Three weeks later, after the partial re-perfusion seen on
ICGA ( bottom middle ), the damaged areas were visible on BAF ( bottom left ). Example of
practical usefulness of OCT-A in a patient with APMPPE (same patient as Figure 1 ). For all of the
established advantages of automated perimetry, there are potential pitfalls with this testing modality
in a patient population that is subject to fatigue-related visual dysfunction. The latter two categories
were analyzed in more details in the next two sections. 4.2. Clinical Research Articles The search
yielded 92 research articles on different disease conditions and different localizations of structures.
In the center, there was hypoautofluorescence corresponding to remaining non-perfusion on ICGA
(crimson arrow). The intraclass correlation coefficients were particularly high at different PMIs, thus
confirming good measurement reliability with the portable OCT. Firstly, OCT-A is indeed a technical
high-grade imaging modality with spectacular research results not necessarily applicable to daily
ophthalmological consultation, but also subject to overinterpretation. Feature papers are submitted
upon individual invitation or recommendation by the scientific editors and must receive. Initially,
there is generally poor concordance between OCT measures of structural integrity and functional
outcomes in patients with acute ON. It provides information on the quasi-histological quality on the
different layers of the retina in the macular and peri-macular areas, as well as on the retinal
thickness. All authors have read and agreed to the published version of the manuscript. International
Journal of Turbomachinery, Propulsion and Power (IJTPP). In logMAR notation, lower scores
correspond to better vision, and as acuity becomes worse, the value of the logMAR increases. A
preliminary experiment was also performed to test the absence of geometric patterns from the
anterior surface of a motionless artificial eye. The VEP is known to be generated at the level of
striate cortex. Not surprisingly, RNFL atrophy tends to be extensive in ON eyes of patients with
NMO. See Full PDF Download PDF See Full PDF Download PDF Related Papers forensik Gresia
Kristi Download Free PDF View PDF Morphological analysis of corneal findings modifications after
death: A preliminary OCT study on an animal model Matteo Nioi The aim of this work was to
describe, for the first time, the morphological modifications, in a three-dimensional mode, of the
central cornea at different intervals since death. In this study, the odds of falling into the NMO
group increased by 8% for every 1-. Given that binocular summation is most likely processed at the
cortical level, MS and ON patients may experience functional limitations due to interruptions in
normal cortical signaling. These very productive groups, in their repeated articles, tend also to
overemphasize their conclusions, with a trend of demonstrating useful daily use. Many of these
studies report new data which is still to be standardized in order to possibly be applied to everyday
routine practice. After an initial thinning of tissues and an enhancement of epithelial reflectivity,
stromal thickness increased from the 2nd up to the 6th hour. Pachymetric map, morphological and
ultrastructural analysis (epithelium, stroma, and endothelium), were performed for each time-point.
Our research showed the usefulness of this approach for the study of coronary injuries, postmortem
ocular changes, forensic entomology, and several other applications of specific forensic interest (the
study of blood stains, fingerprints, and hair bulbs for personal identification, as well as the study of
materials found in the crime scene for comparation, or anti-fraud investigation). To go further and
investigate whether routine use of OCT-A was suited for everyday diagnosis and follow-up in uveitis
in place of conventional dye angiography, or whether this represented a mystification, we conducted
an extensive literature review in search of arguments in one direction or the other. Besides the many
drawbacks of OCT-A mentioned by the article itself, the article was characterized by several flaws.
Example of practical usefulness of OCT-A in a patient with APMPPE (same patient as Figure 1 ).
Sebag Download Free PDF View PDF The role of micro-computed tomography in forensic
investigations Alison Brough Download Free PDF View PDF See Full PDF Download PDF
Loading Preview Sorry, preview is currently unavailable. The articles gave information either on
retinal circulation, choroidal circulation or both. The aim of this book is to present elaborative
information on OCT in a wide spectrum of fields including oncology, engineering, ophthalmology
and atherosclerosis. The mean RNFL values were significantly lower in recurrent ON eyes (64.
Conclusion: To date, no evidence was found in the literature that OCT-A can replace the classic dye
methods; however, it can complement them. Optical coherence tomography (OCT) is an imaging
technique providing high-resolution cross-sectional images in several fields of engineering and
medicine. Yet in studies showing significantly more RNFL thinning in NMO ON eyes relative to MS
ON eyes, there has been considerable overlap in the distribution of RNFL values.
This patient was diagnosed and followed as MEWDS thanks to BAF. More recently, another
complementary imaging method, OCT-angiography (OCT-A), further allowed retinal and choroidal
circulation to be imaged without the need for dye injection. This review paper considers the past,
current and future advances in cadaver cardiac imaging which, if successful, will take radiological
imaging one step closer to the widespread introduction of near virtual autopsies. In this way, the
relative contribution of cortical compensation to visual recovery, and the factors that govern the
potential for cortical plasticity, may be determined after acute ON in patients with CNS
demyelinating disorders. Note that from the first issue of 2016, this journal uses article numbers
instead of page numbers. A disadvantage of a montage is the presence of artifacts including, but not
limited to, displacement, shadowing and vessel displacement. The terms mostly used to qualify the
contribution of the articles in this group were “complementary to dye methods”, “adjunct”,
“supplementing” and other similar terms. Fifteen articles were reviews, none of which hinted that
OCT-A could replace dye methods. It is noteworthy that patients who manifest an inter-eye
asymmetry in RNFL thickness of 15. Article selection for systematic review using the terns “OCT-A
and uveitis”, “OCTA and uveitis” and “OCT-angiography and uveitis”. Pachymetric map,
morphological and ultrastructural analysis (epithelium, stroma, and endothelium), were performed
for each time-point. Multiple requests from the same IP address are counted as one view. In the case
of automated perimetry, this requires more than comparing a current visual field test with the most
recent previous visual field test; rather, trends should be observed over time. International Journal of
Environmental Research and Public Health (IJERPH). FD-OCT devices include a spectrometer in
the receiver that analyzes the spectrum of reflected light on the retina or ocular surface and
transforms it into information about the depth of the structures according to the Fourier principle.
Articles were assigned to the following categories: (1) technical informative articles, (2) research
articles and (3) review articles. Interestingly, in ON eyes lower MV values were associated with color
vision loss. Provides non-scientists and non-engineers basic understanding of Optical Coherence
Tomography applications and issues. Yet, there was no correlation between OCT measures and color
vision testing. During each measuring session, a pulse oximetry was used for continuously measuring
the heart rate and oxygen saturation (SpO 2 %). Three weeks later, after the partial re-perfusion seen
on ICGA ( bottom middle ), the damaged areas were visible on BAF ( bottom left ). Perimetry has
evolved through stages since original confrontation-based techniques to allow quantification and
statistical analysis in its currently used computerized forms. This provides critical information about
visual function, including both central and peripheral channels. We further counted and listed the
number of “OCT-A articles for uveitis” per year, starting in 2016. Journal of Experimental and
Theoretical Analyses (JETA). Yellow arrows show new areas of drop-out before regression of lesions
following introduction of corticosteroids (frames at the extreme right). Journal of
Otorhinolaryngology, Hearing and Balance Medicine (JOHBM). References Novotny, H.R.; Alvis,
D.L. A method of photographing fluorescence in circulating blood in the human retina.
Hypoautofluorescence indicates loss of RPE due to atrophy or scarring. One of the challenges in
interpreting color vision outcomes is that various modalities are used, and there is less standardization
relative to HCVA, LCLA, and perimetry testing. However, post-acutely, LCLA can be used to detect
persistent visual deficits that may otherwise be missed in patients who have regained “normal” vision
on standard HCVA and visual field testing. Example of practical usefulness of OCT-A in a patient
with APMPPE (same patient as Figure 1 ).
Articles were assigned to the following categories: (1) technical informative articles, (2) research
articles and (3) review articles. Tap to rate Write a review Review must be at least 10 words Book
preview Optical Coherence Tomography - Mark E. Our research showed the usefulness of this
approach for the study of coronary injuries, postmortem ocular changes, forensic entomology, and
several other applications of specific forensic interest (the study of blood stains, fingerprints, and hair
bulbs for personal identification, as well as the study of materials found in the crime scene for
comparation, or anti-fraud investigation). Sebag Download Free PDF View PDF The role of micro-
computed tomography in forensic investigations Alison Brough Download Free PDF View PDF See
Full PDF Download PDF Loading Preview Sorry, preview is currently unavailable. Herbort, C.P., Jr.;
Takeuchi, M.; Papasavvas, I.; Tugal-Tutkun, I.; Hedayatfar, A.; Usui, Y.; Ozdal, P.C.; Urzua, C.A.
Subscribe to continue reading Start your free days Page 1 of 1 Home Ebooks Physics Footer menu
Back to top About About Everand Press Our blog Join our team. Herbort, C.P., Jr.; Takeuchi, M.;
Papasavvas, I.; Tugal-Tutkun, I.; Hedayatfar, A.; Usui, Y.; Ozdal, P.C.; Urzua, C.A. As far as
technical matters are concerned, OCT-A montage was used to obtain a wider field of vision.
Comparing RNFL changes in ON associated with neuromyelitis optica to RNFL changes in ON
associated with MS Neuromyelitis optica (NMO) is a severe inflammatory process of the optic
nerves and spinal cord (with occasional brain involvement) that is generally associated with poor
clinical recovery. After excluding case report articles, 114 articles were retained: 4 in 2016, 17 in
2017, 14 in 2018, 21 in 2019, 14 in 2020, 18 in 2021 and 26 in 2022. In a related study, there was
significantly worse RNFL thinning in NMO ON eyes (64. Since the 24th hour, the epithelium
disappeared in 50% of cases and the anterior chamberdepth progressively decreased. Optical
Coherence Tomography Angiography (OCT-A) in Uveitis: A Literature Review and a Reassessment
of Its Real Role. It should be integrated, like all other complementary imaging methods cited, in the
modern multimodal appraisal of uveitis. See Full PDF Download PDF See Full PDF Download PDF
Related Papers forensik Gresia Kristi Download Free PDF View PDF Morphological analysis of
corneal findings modifications after death: A preliminary OCT study on an animal model Matteo
Nioi The aim of this work was to describe, for the first time, the morphological modifications, in a
three-dimensional mode, of the central cornea at different intervals since death. Journal of
Experimental and Theoretical Analyses (JETA). After one hour, OCT imaging was repeated (second
session) by a different operator masked to the study to verify the reliability of results. The situations
where OCT-A represented a significant practical contribution to the practical appraisal of uveitis were
identified. In the case of automated perimetry, this requires more than comparing a current visual
field test with the most recent previous visual field test; rather, trends should be observed over time.
Different values were observed between the first and second samples in each group. The intraclass
correlation coefficients were particularly high at different PMIs, thus confirming good measurement
reliability with the portable OCT. The purpose of this study was to determine the repeatability and
reproducibility of post-mortem CCT measurements by using a real-time, portable OCT system on an
animal model. As dye exams offer a dynamic analysis blood flow and flow of liquids, the
permeability of the inner retinal barrier (presence of leakage or not) and of the outer retinal barrier
(leakage through the RPE) can be investigated. Optical Coherence Tomography Angiography (OCT-
A) in Uveitis: A Literature Review and a Reassessment of Its Real Role. Not surprisingly, RNFL
atrophy tends to be extensive in ON eyes of patients with NMO. European Journal of Investigation
in Health, Psychology and Education (EJIHPE). Indeed, the patient developed a recurrence 2 years
later and the diagnosis was reverted to MFC. Methods: A literature search in the PubMed database
was performed using the terms OCT-angiography and uveitis, OCTA and uveitis and OCT-A and
uveitis. The CMO and posterior pole pathologies can be further assessed closely and non-invasively
by follow-up OCTs. Herbort, Carl P., Jr., Masaru Takeuchi, Ioannis Papasavvas, Ilknur Tugal-Tutkun,
Alireza Hedayatfar, Yoshihiko Usui, Pinar C.
This list included case reports, research articles, technical articles and reviews. Furthermore, a
synthesis of the main practical applications of OCT-A in the management of uveitis was attempted.
Interestingly, in ON eyes lower MV values were associated with color vision loss. For more
information on the journal statistics, click here. Cancel anytime. Ebook 503 pages 12 hours Optical
Coherence Tomography: Principles and Applications Show full title By Mark E. Journal of
Cardiovascular Development and Disease (JCDD). Indeed, the patient developed a recurrence 2
years later and the diagnosis was reverted to MFC. Given that binocular summation is most likely
processed at the cortical level, MS and ON patients may experience functional limitations due to
interruptions in normal cortical signaling. Glucose, urea, creatinine, 3-?-hydroxybutyrate, sodium and
chloride were tested. The VEP is known to be generated at the level of striate cortex. Please note
that many of the page functionalities won't work as expected without javascript enabled. OCT
images are created by measuring the intensity of reflected or back scattered light which is scanned
across the tissue and material. However, post-acutely, LCLA can be used to detect persistent visual
deficits that may otherwise be missed in patients who have regained “normal” vision on standard
HCVA and visual field testing. Moreover, EDI-OCT, contrary to ICGA, can provide accurate three-
dimensional images of the choroidal layers with precise measurement of the depth and morphology
of the lesions. 1.4. Blue Light Fundus Autofluorescence (BAF) BAF is a valuable tool which is
becoming more and more frequently used in daily practice by ophthalmologists. The main practical
advantage of OCT over FA was the possibility of closer follow-up of CMO and better fine-tuning of
treatment without the need for dye injection. OCT-A also failed to show which mechanism was at
the origin of drop-out areas, choriocapillaritis or stromal choroiditis, which a dynamic analysis of
ICGA frames is able to demonstrate. Over the past two decades, optical coherence tomography
(OCT) has revolutionized basic research on various biological systems 1,2. We further counted and
listed the number of “OCT-A articles for uveitis” per year, starting in 2016. Snellen visual acuity is
usually expressed as a fraction with the numerator equal to the distance from the chart and the
denominator being the size of the smallest line that can be read. The importance of diagnosing NMO
early cannot be overstated because the natural history of ON associated with this disorder is poor
and long-term immunosuppressive therapy is needed. Herbort, Carl P., Jr., Masaru Takeuchi, Ioannis
Papasavvas, Ilknur Tugal-Tutkun, Alireza Hedayatfar, Yoshihiko Usui, Pinar C. Yet in studies
showing significantly more RNFL thinning in NMO ON eyes relative to MS ON eyes, there has
been considerable overlap in the distribution of RNFL values. A preliminary experiment was also
performed to test the absence of geometric patterns from the anterior surface of a motionless
artificial eye. High-contrast visual acuity is determined under optimal circumstances of high contrast
and high luminance, and it is therefore not surprising that HCVA tends to manifest the most obvious
early improvement in acute ON patients. This group employed OCT, HCVA, LCLA (1.25% and
2.5%), perimetry, and Farnsworth 100 Hue color vision testing. Editors select a small number of
articles recently published in the journal that they believe will be particularly. Although the basic
assumption in achieving reliable OCT measurements on ocular tissues is the visual fixation (VF) of
the patient at a fixation target, in some cases this condition is impossible to obtain (e.g. for blind or
visually-impaired patients, or for post-mortem studies of ocular changes) 8. At presentation,
numerous areas of hyperautofluorescence were observed ( left ), but disappeared 12 weeks later
without treatment ( right ). After excluding case report articles, 114 articles were retained: 4 in 2016,
17 in 2017, 14 in 2018, 21 in 2019, 14 in 2020, 18 in 2021 and 26 in 2022. OCT imaging showed a
motionless, stable anterior surface of the artificial eye and in dry eye patients.