Cervical Cancer Literature Review: Navigating the Complexity

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If you do smoke, speak to your specialist about tactics to improve you to quit smoking. The standard
treatment for women once they are diagnosed with cervical cancer is either with radical surgery or
radical chemoradiation. Search results of the identified titles and abstracts will be merged and
managed in Endnote. While screening with the Pap test or other more recently evaluated tests have
resulted in low cervical cancer rates in high resource countries, the lack of screening options in low
resource countries means that many women present with symptoms reflective of advanced disease
and so the chance of survival is low even with aggressive treatment. During the treatment, avoid
visiting public places so as not to get an infection. Authors may be contacted for further clarification
or additional information using the email provided in the studies or by a profile search in Google if
needed. Multiple modalities exist for the complete eradication of precancerous as well as malignant
lesions, including surgical, radiation and chemotherapy. Multiple strains of the human papillomavirus
(HPV), an STDs, perform a role in producing most cervical cancer. About 70% of cervical cancers
are caused by type 16 and 18 HPV. Sometimes the specialist can exclude only the area of the Cervix
that carries cancer cells. By using the site you are agreeing to this as outlined in our privacy notice
and cookie policy. Until Decemberwhen the national roll-out of human papillomavirus HPV primary
testing was completed, screening was done using liquid-based cytology. Getting a cervical cancer
vaccine to inhibit HPV infection may overcome your chance of cancer. The search strategy for
PubMed (presented below) will be modified to make it appropriate for search in each database. All
disagreements (including those related to merging, screening, and selection of search results) will be
resolved in an open discussion between the two researchers. Mulhall and Jermaine I.G. Coward,
Mater Adult Hospital, Department of Medical Oncology, Raymond Terrace, Brisbane, QLD,
Australia, and others). In the meantime, to ensure continued support, we are displaying the site
without styles and JavaScript. This is a tragedy in part because cervical cancer affects women usually
a decade sooner than other cancer when those women are in their reproductive years and in the
prime years in the labour force. Under two recovery scenarios, we estimate the impact of COVID on
cervical cancer over one screening cycle 3 years at ages 25—49 and 5 years at ages 50—64 years.
Despite having effective screening and diagnostic methods, cervical cancer continues to be of major
concern worldwide. A narrative synthesis will be based on the summarized table. 11 We will conduct
a meta-analysis after gathering sufficient data. Europe PMC requires Javascript to function
effectively. The persistent infection hrHPV (type 16 and 18) is responsible for more than 70% of
cervical cancer, however, low-risk HPV i.e. type 6 and 11 causes approximately 90% of genital
warts. Estevez-Garcia, E. Calvo, I. Duran and I. Diaz-Padilla, Gynecologic Cancer Program. The
exciting role that telemedicine offers for geographically isolated setting is presented. Gardasil 9 is an
HPV vaccine licensed by the U.S. Food and Drug Administration and can be practiced for girls and
boys. Many times, radiotherapy is combined with chemotherapy for effective cure. That has changed
since screening tests became widely available. Avoid going grocery or drugstore; provide yourself
with emergency medicines through an online pharmacy in the Philippines to avoid crowded places;
also, try to use a private cab while visiting the clinics. The earliest stages of cervical cancer can be
treated with surgery or radiation combined with chemotherapy and the later stages are treated with
radiation combined with chemotherapy.
Under two recovery scenarios, we estimate the impact of COVID on cervical cancer over one
screening cycle 3 years at ages 25—49 and 5 years at ages 50—64 years. The special situation of
women found to be pregnant during the diagnosis of pre-invasive or invasive cervical cancer; the
diagnosis and management principles are reviewed. Cervical cancer is a curable and preventable
disease. Other types of cervical cancer may Disclosure: The authors have nothing to disclose. In
England, cervical screening is mostly carried out in general practice by specially trained nurses. In
patients below poverty line, 78.6%, showed invasive c. In some cases, treatment is intense up to
stage 4. Screening has also seen major advances with implementation of HPV testing on a larger
scale. Just as poliomyelitis has almost been eliminated in the lifetime of one generation, we look
forward to the eliminated of oncogenic HPV and its deadly ramifications particularly for women
exposed to this virus. (Imprint: Nova Biomedical ). Materials and methods: This was a cross
sectional descriptive study carried out in a tertiary hospital in South India in January 2015.
Background You are using a browser version with limited support for CSS. Ethical committee
clearance was obtained prior to start the study. Multiple modalities exist for the complete eradication
of precancerous as well as malignant lesions, including surgical, radiation and chemotherapy. The
cervical cancer burden is over 18 times greater in low- and middle-income countries (LMICs) than in
high-income countries. 15 genotypes of the Human Papilloma Virus found to cause cervical cancer
and are transmitted sexually. One such oncogenic virus is the Human Papilloma Virus (HPV), among
the different strains of which around 15 strains are related to the cause of cervical cancer. Cervical
cancer is the main cancer found in developing countries. A Review and Analysis of Approaches to
Research Synthesis. This website requires cookies, and the limited processing of your personal data
in order to function. Quantitative information will be reported in ranges. Search results of the
identified titles and abstracts will be merged and managed in Endnote. Each of the merged studies
will be further screened, and full-text documents will be downloaded and arranged in a directory
according to the type of publication (peer-reviewed article, thesis, grey literature, reports, etc.). Any
disagreement between the two independent researchers will be resolved in an open discussion. This
protocol describes a planned systematic review that will collate and report the experiences of
implementation of cervical cancer screening and associated factors in Nepal over the last two decades
to identify knowledge gaps to inform future implementation strategies. Protocol for systematic
literature review on implementation of cervical cancer screening and associated factors in Nepal from
2000 to 2018. The study included all diagnosed cases of carcinoma of cervix admitted in
Gynaecology ward. Its prevalence depends upon genetic and non-genetic factors. Keywords:
Cervical cancer, Chemotherapy, Curable, Human Papilloma Virus, Preventable,
Radiotherapy,Vaccination. Most cancers are found in cells on the outside of the Cervix. Meanwhile,
over half a million new cases are added each year. Identification of risk factors is necessary to curb
the disease.Methods: In this study 1000 married women, attending A.H. Regional Cancer Centre
Gynecological-Oncology OPD, from April 2016- March 2017 were randomly selected and subjected
to Pap smear test of cervix and abnormal smears, biopsied.
The Critical Appraisals Skills Programme (CASP) checklist for quantitative and qualitative studies
will be used to assess the clarity in aims and relevance of the study, the study design, sample size,
and data collection method. The search strategy for PubMed (presented below) will be modified to
make it appropriate for search in each database. This disease affects the lower part of the uterus (start
of the cervix area). Recent Activity. Important Message We are sorry, we are unable to retrieve the
citation details for this record. These are average continuation rates and do not appeal to everyone.
Barriers and facilitators to uptake of cervical cancer screening among women in Uganda: A
systematic review. Europe PMC requires Javascript to function effectively. Keywords: Cervical
cancer, Chemotherapy, Curable, Human Papilloma Virus, Preventable, Radiotherapy,Vaccination. In
the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.
As well we discuss the role of neoadjuvant chemotherapy as a means of down staging the disease.
Currently screening method includes visual inspection with acetic acid (VIA), cervical cytology,
detection of HPV based on DNA and RNA. The citation records will then be exported to Endnote.
So if you are facing any symptoms, consult your specialist or doctor to get your treatment done in
the early stages. A Review and Analysis of Approaches to Research Synthesis. CaCx is the second
most prevalent cancer among females in India contributing to 14% of all cancers (NCRP, 2015). The
duration of disruption in both scenarios is 6 months. In this book we discuss novel operative options
in early stage invasive cervical cancer as a means of preserving fertility. While screening with the Pap
test or other more recently evaluated tests have resulted in low cervical cancer rates in high resource
countries, the lack of screening options in low resource countries means that many women present
with symptoms reflective of advanced disease and so the chance of survival is low even with
aggressive treatment. Sometimes the specialist can exclude only the area of the Cervix that carries
cancer cells. Search results of the identified titles and abstracts will be merged and managed in
Endnote. Both scenarios result in similar numbers of excess cervical cancers: vs. Approximately 70%
of cer-vical cancers are of the squamous cell type and nearly 25% are of the adenocarci-noma type
that develop from glandular cells. Early detection and treatment of cervical precancerous lesions
leads to reduce in cervical cancer morbidity and mortality. Cervical cancer is a curable and
preventable disease. Download Free PDF View PDF See Full PDF Download PDF Loading Preview
Sorry, preview is currently unavailable. Cervical cancer is the 2nd most frequent cancer among
women globally, among a predictable 528,000 latest cases along with 266,000 deaths between
women every year. Materials and Method: This was a prospective observational study of carcinoma
of cervix carried out at a tertiary care hospital. The exciting role that telemedicine offers for
geographically isolated setting is presented. However, there are still many countries where the
population based prevalence has not yet been identified. Screening has also seen major advances
with implementation of HPV testing on a larger scale.
Screening has been offered to women aged 25—49 years at 3-yearly intervals although the plan is to
extend to 5-yearly with HPV testing and to those aged 50—64 Literature Review Cervical Cancer at
5-yearly intervals. The high burden of this disease necessitates identifying relevant evidence to
inform policy development and guidelines. Early stages of cervical cancer may be completely
asymptomatic. Multiple modalities exist for the complete eradication of precancerous as well as
malignant lesions, including surgical, radiation and chemotherapy. In developed countries, HPV
infections have decreased more than half over a period of time by introducing screening and
vaccination programmes. Avoid going grocery or drugstore; provide yourself with emergency
medicines through an online pharmacy in the Philippines to avoid crowded places; also, try to use a
private cab while visiting the clinics. Authors may be contacted for further clarification or additional
information using the email provided in the studies or by a profile search in Google if needed. Each
researchers will independently perform these activities. Cervical screening aims to identify abnormal
cells in the cervix and treat them before they progress to cancer. That has changed since screening
tests became widely available. A PRISMA flow chart diagram will be used to summarise the search
and selection strategies. 10. It can also be performed inside the body, practicing a metal pipe in the
uterus or vagina. Quantitative information will be reported in ranges. Furthermore, we will develop a
framework to cover the gaps in the current evidence, drawing on the principles from the framework
suggested by Robinson et al. Abstracts of each study will be screened by applying the eligibility
criteria and noted. In this book we discuss novel operative options in early stage invasive cervical
cancer as a means of preserving fertility. In the present study, maximum subjects 15 (35.71%) were
in the age group of 41-50 years followed by 12 (28.57%) in the age group of 61-70 years. However,
in this article, we have summarized and revealed some important statistics about cervix uteri cancer
that describe its epidemiology, risk factors, relation to age, treatments, staging and similar aspects.
Barriers and facilitators to uptake of cervical cancer screening among women in Uganda: A
systematic review. With this view, the present study was planned to find out risk factors of cases of
carcinoma of cervix attending tertiary care hospital. The search for peer-reviewed literature in
PubMed will e.g. be conducted with the following search strategy. Just as poliomyelitis has almost
been eliminated in the lifetime of one generation, we look forward to the eliminated of oncogenic
HPV and its deadly ramifications particularly for women exposed to this virus. (Imprint: Nova
Biomedical ). In some cases, treatment is intense up to stage 4. Identification of risk factors is
necessary to curb the disease.Methods: In this study 1000 married women, attending A.H. Regional
Cancer Centre Gynecological-Oncology OPD, from April 2016- March 2017 were randomly
selected and subjected to Pap smear test of cervix and abnormal smears, biopsied. Cervical cancer is
preventable, and effective screening programs reduce morbidity and mortality associated with this
type of cancer; however, the programs vary according to socio-economic conditions of each country,
which reflected in the increased incidence, morbidity, mortality from cervical cancer in developing
countries. Additional papers will be retrieved through hand-searching of citations and reference list
tracking. To obtain the best experience, we recommend you use a more up to date browser or turn off
compatibility mode in Internet Explorer. This article is focussing on recent update on hrHPV and its
association in Indian context. If you do smoke, speak to your specialist about tactics to improve you
to quit smoking.
Despite having effective screening and diagnostic methods, cervical cancer continues to be of major
concern worldwide. In over 80 countries, including LMICs, HPV vaccination is now included in the
national program. We present the capacity for HPV vaccines to markedly reduce cervical cancer
rates. A filter by year (1 January 2000 to 31 December 2018) will be applied for the search in each
database. CaCx is the second most prevalent cancer among females in India contributing to 14% of
all cancers (NCRP, 2015). Multiple modalities exist for the complete eradication of precancerous as
well as malignant lesions, including surgical, radiation and chemotherapy. The exciting role that
telemedicine offers for geographically isolated setting is presented. For statistical analysis, STATA 15
(Stata Corp, College Station, TX, USA) will be used and a heterogeneity test will be performed
using chi-square statistics. The occurrence of HPV is greater in countries where cervical cancer
burden is high. Authors may be contacted for further clarification or additional information using the
email provided in the studies or by a profile search in Google if needed. A Review and Analysis of
Approaches to Research Synthesis. Besides PCR results and cytological evaluation of the samples
were compared. We discuss novel screening techniques including HPV testing. The study included
all diagnosed cases of carcinoma of cervix admitted in Gynaecology ward. The duration of
disruption in both scenarios is 6 months. Both scenarios result in similar numbers of excess cervical
cancers: vs. To browse Academia.edu and the wider internet faster and more securely, please take a
few seconds to upgrade your browser. There are risk factors for cervical cancer worldwide, mainly
persistent infection of high risk HPV, especially genotypes 16 and 18 viruses. The high burden of this
disease necessitates identifying relevant evidence to inform policy development and guidelines.
However, these interventions will take a few years to show their impact. Cervical cancer is
preventable, and effective screening programs reduce morbidity and mortality associated with this
type of cancer; however, the programs vary according to socio-economic conditions of each country,
which reflected in the increased incidence, morbidity, mortality from cervical cancer in developing
countries. Several risk factors have been recognized that raise a woman’s chance of growing cancer.
Early detection and treatment of cervical precancerous lesions leads to reduce in cervical cancer
morbidity and mortality. So if you are facing any symptoms, consult your specialist or doctor to get
your treatment done in the early stages. This chapter discusses the management of cervical cancer
based on the stage of disease, including attention to palliation and quality of life issues.
Environmental and age-related factors also play an important role, and these areas are open for
research to discover exact relationships. It showed bimodal peak of incidence, 33(89.19%) were
Hindus, 30 (71.42%) were illiterate, 25 (59.52%) were grand multiparous, 26 (61.90%) were married
at the age less than 16 years and 37 (88.09%) were non immunocompromised. However, if agreement
is not reached, a third independent reviewer will be consulted. The effect of a delay in attendance to
cervical screening is explored under two scenarios.