Cateter Implante Por Nefrologos Rev 24

You might also like

Download as pdf or txt
Download as pdf or txt
You are on page 1of 12

Received: 26 October 2021 Revised: 27 April 2022 Accepted: 7 June 2022

DOI: 10.1111/sdi.13118

REVIEW ARTICLE

Peritoneal dialysis catheter insertion techniques by the


nephrologist

Bak Leong Goh1 | Christopher T. S. Lim2

1
Department of Nephrology & Clinical
Research Centre, Hospital Serdang, Kajang, Abstract
Malaysia Peritoneal dialysis (PD) catheter is the lifeline of PD patients, and despite the overall
2
Department of Medicine, Faculty of Medicine
strength of the PD program in many countries, PD catheter survival remains the
and Health Sciences, Universiti Putra Malaysia,
Serdang, Malaysia major weakness of the program. The prompt and effective implantation of the
PD catheter, as well as speedy management of complications arising from catheter
Correspondence
Professor Dr. Bak Leong Goh, Department of insertion, remains crucial for the success of the program.
Nephrology & Clinical Research Centre,
Hospital Serdang, Jalan Puchong, 43000
Kajang, Selangor, Malaysia.
Email: bak.leong@gmail.com

Funding information
No funding was received for this article.

1 | I N T RO DU CT I O N 1.1 | Review of catheter design and option

Traditionally, in many countries, PD catheter was implanted by sur- Purpose: To understand what has been tried and what does work.
geons. This invariably resulted in an inherent delay where potential Long-term PD catheter was made a reality by the development of
patients were exposed to hemodialysis and in the process developed the first long-term indwelling catheter (first by Sir Henry Tenckhoff in
a loss of interest in PD. Patients who experienced complications such 1968), created by adding Dacron® cuffs to the earlier silicon-rubber
as catheter malfunction were often forced into long waiting times catheters.15 Until today, modern catheters still use Tenckhoff's design
1–9
before catheter-related problems can be solved. These factors par- of variations of it.
tially, if not mostly, explained why PD penetration remains low at
around 10% around the world, despite its many advantages such as
preservation of residual renal function,10,11 lessened incidence of left 1.1.1 | Early designs and concepts
ventricular hypertrophy,12 cost-effectiveness,13 and reduced cardio-
vascular events.14 While great developments in clinical and basic sci- An ideal catheter should be simple, safe, and long-lasting, with a mini-
ence knowledge have occurred in the field of PD, PD access remains mal rate of access-related complications while ensuring a rapid dialy-
a challenge and debates remain concerning the preferred access, sate flow rate. Several subcutaneous and intraperitoneal designs were
implantation technique, exit-site care, and ideal operators. Attempts proposed as better devices subsequently. The catheter may be single-
and search for evidence-based recommendations usually face with or double-cuffed with a straight or curled intraperitoneal segment.
limitations of a small number of randomized controlled trials (RCT)
and the inadequacy of statistical power of small sample size studies.
Without the purpose of extensively reviewing all the details on PD 1.1.2 | Dr. Henry Tenckhoff's contributions
access, an update on various commonly available accesses, insertion
techniques especially from a nephrologist perspective will be Since its development in 1968, Tenckhoff catheter is still the most
presented. widely used, either by medical or surgical methods.

24 © 2022 Wiley Periodicals LLC. wileyonlinelibrary.com/journal/sdi Semin Dial. 2024;37:24–35.


1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
GOH AND LIM 25

Each PD catheter is comprised of three parts: the internal tip to avoid catheter-tip migration.19 However, these
variations have not shown any consistent advantage in comparison to
• Intra-abdominal segment standard PD catheters. Therefore, the experience of the center should
• Subcutaneous tunnel segment dictate the type of catheter used. Table 1 listed the results of the
• External segment randomized control trials on the type of catheters.
Some studies, including the International Society for Peritoneal
The intra-abdominal segment has multiple small side-holes and an Dialysis (ISPD) consensus, favored double-cuffed in comparison with
open terminal end. The subcutaneous segment has two cuffs, the single-cuffed PD catheters in terms of better survival, longer time to
outer cuff is placed just under the skin (2–3 cm) at the exit site, and first peritonitis, and fewer exit site infections.27 Theoretically, the
the deep cuff is placed preferably in the rectus sheath just external to coiled catheter offers less infusion pain, fewer catheter migration, and
the fascia covering the parietal peritoneum. omentum wrap. However, the available studies provided inconsistent
results as shown in Table 1. Our center analysis of 126 patients and a
recent Cochrane analysis also failed to show the impact of different
1.1.3 | Current variation and alternate option catheter types on peritonitis occurrence and rate.28,29

Straight Easy to place by percutaneous technique


Easy to remove and replace 1.2 | Review of basic anatomy implementation
Outflow problems and rectal discomfort are more sites and catheter function
commonly reported
Curled Same as above, but better patency and better outflow Purpose: To understand the inter-relationship between anatomy.
reported There are generally two common approaches in implanting the
Does not impinge on the rectum PD catheter. The median or infra-umbilical approach is generally
Swan Neck Permanently curve and has less reported migration16 easier to perform. This involves going through the thinnest layer of
Missouri Combination of Toronto Western and Swan Neck abdominal fascias. The subcutaneous layer is dissected down to the
catheter linea alba and implantation is performed. As the catheter is lying
Need to be placed and manipulated surgically17,18 lower, there is a risk that the tip of the PD catheter can be deflected
upwards by pelvic organs during catheter advancement. Moreover,
PD catheters with different intraperitoneal designs include the low lying catheter can potentially cause pelvic wall irritation.
Toronto Western (silicon discs perpendicular to the catheter) and Furthermore, the inferior gastric arteries, which run at the medial
Missouri (Dacron disc and silicon bead) catheters. The purpose of border of rectus muscles can be lacerated during the tunneling
these designs is to reduce pericatheter leak and migration and at the process (Figure 1). This technique is also inherently flawed by posi-
same time ensure better flow. Some devices are created to stabilize tioning the deep cuff in the subcutaneous space external to the mus-
the catheter with the intra-peritoneal disk, bead, or flange. There are cle fascia as they do not provide adequate tissue attachment to the
also self-locating catheters designed with a tungsten weight added to deep cuff, which can result in leaks, hernias, and superficial cuff

TABLE 1 Randomized controlled trials (RCTs) of PD catheter designs

No of
Author patients Type of catheter Duration Outcomes
20
Akyol et al. 40 Straight versus coiled 23 months No difference in catheter-related infections
21
Eklund et al. 60 Single versus double cuffed 20 months No difference in catheter-related infections and
catheter survival
Eklund et al.22 40 Straight double cuffed versus Swan-neck 12 months No difference in catheter-related infections and
(double cuffed, coiled) catheter survival
Johnson et al.23 132 Straight Swan neck, double cuffed versus double 24 months No difference in catheter-related infections but
cuffed, coiled coiled catheter has higher technique failure
Lye et al.24 40 Straight double cuffed versus Swan-neck 12 months Lower exit-site infection in the Swan-neck
(double cuffed, coiled) group. Peritonitis and catheter survival are
similar.
Nielsen et al.25 72 Straight, single cuffed versus permanent bent 6 months No difference in catheter removed from
Swan-neck (curled, single cuffed) peritonitis. The straight catheter has more
migration.
Scott26 89 Straight, double cuffed versus Toronto Western 12 months No difference in catheter-related peritonitis and
double disk or Oreopoulos standard coiled catheter survival

Abbreviation: PD, peritoneal dialysis.


1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
26 GOH AND LIM

F I G U R E 1 The relationship
of the inferior gastric arteries
with paramedian versus infra-
umbilical approach

TABLE 2 RCTs of different implantation techniques and outcomes

No of
Author patients Technique Duration Outcomes
31
Gadallah et al. 148 Peritoneoscopic versus mini-laparotomy 16 months Higher infection rate and lower catheter survival in
the laparotomy group
Jwo et al.32 77 Laparoscopic versus mini laparotomy 48 months No difference in catheter survival or infection
Atapour et al.33 64 Surgical versus percutaneous 2 months Higher flow issue and exit site infection in the surgical
group
Voss et al.34 113 Laparoscopic versus percutaneous 12 months Similar catheter survival. The laparoscopic group has
(fluoroscopic) more leaks and peritonitis

Abbreviation: RCT, randomized controlled trial.

extrusion. On the other hand, overzealous implantation of the deep 2. Through peritoneoscopy, in which a small (2-mm) optical instru-
cuff will push the cuff deep into the peritoneal cavity. This results in ment is used to choose the optimal location of the catheter within
flow failure secondary to omentum wrap. the peritoneum, and the catheter is advanced into the same
The paramedian approach, despite going through a thicker layer location through the Quill® assembly after the peritoneoscopy.
of rectus muscles, has the advantage that it can overcome the above 3. Through open laparotomy, a surgical technique in which layers of
risks. Thus, it is associated with fewer early postoperative complica- tissue are separated under direct vision.
tions with better PD catheter and overall patient survival.30 For these 4. Through laparoscopy where insertion of a peritoneal dialysis cath-
reasons, published guidelines have identified the best-demonstrated eter is usually performed under general anesthesia (GA). The abdo-
practice for insertion of the catheter will be through a paramedian men has to be insufflated and several small incisions are made.
approach and to implant the deep cuff within the musculature of the
abdominal wall.27 There are not many randomized control trials that compare the
different implantation techniques concerning the outcomes. Gener-
ally, as summarized in Table 2, surgical methods have more complica-
1.3 | Catheter implantation options tions as compared to medical methods.
Before insertion of the catheter, the following are to be
Purpose: To be aware of the advantages and disadvantages of the recommended.
techniques.
There are four methods of placement of PD catheters: Patient preparation

1. Through Seldinger's technique where a blind puncture is Cardinal rules


done, then a needle is inserted into the abdomen, a guidewire
placed, a tract dilated, and the catheter inserted through a 1. Each center should have a dedicated team involved in the implan-
sheath. tation and care of peritoneal catheters.
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
GOH AND LIM 27

2. PD catheter insertion should not be delegated to inexperienced Prophylaxis antibiotic


unsupervised operators.
Single preoperative dose of prophylactic antibiotic to provide
Informed consent anti-staphylococcal coverage will be administered immediately before
the PD catheter implantation.
Patients should be informed of the potential complications. Dur-
ing this time, the nature, indication, and complications that may arise Anesthesia, analgesia, and conscious sedation
from the procedure are explained to the patient. Evaluation of the
patient's coagulation status is also indicated. Patients with end-stage kidney disease generally have multiple
co-morbidities leading to increased risk of GA.36 Laparoscopic inser-
Preoperative assessment tion of a PD catheter requires GA for the creation of CO2 pneumoper-
itoneum and visualization of the abdomen. Even though laparoscopic
This should include thorough examination searching for hernias insertion of PD catheter by creating nitrous oxide pneumoperitoneum
that may be repaired at the time of insertion (or before), and scars under local anesthesia has been described, the vast majority of cases
from previous abdominal surgery. Selection of the most appropriate using laparoscope will need GA.37 In patients who are not suitable for
catheter type, marking of the insertion and exit site location should be GA, peritoneoscope or percutaneous technique, performed under
performed. local anesthesia with analgesia and sedation, should be preferred.
Analgesia and sedative agents frequently used during peritoneoscope
Bowel preparation technique are lignocaine 2% (10 ml), fentanyl (10 mcg and titrate up
to100 mcg), and midazolam (1-mg titrate up to 5 mg). They are
Constipation is a known cause of catheter dysfunction.35 There- favored due to their anxiolytic and amnesic effects.
fore, preoperative bowel preparation is recommended to optimize
peritoneal access. This can be achieved by the administration of a A. Medical
stimulant suppository a day before surgery.
1. Seldinger technique
Preparation of operation site
The procedure can be carried out in the treatment room (with full
The patient is advised to shower on the day of the procedure sterile precautions). After the patient has voided urine, the appropriate
with chlorhexidine soap wash of the planned surgical site and removal site for the primary incision is selected; ideally, a paramedian
of body hair is done in the preoperative holding area, preferably with approaches for reasons outlined earlier (Figure 2). A 2- to 3-cm long
electric clippers. incision is made and the subcutaneous tissue is dissected down to the

FIGURE 2 Showing combinations of intraperitoneal and extraperitoneal designs and the lateral view in relation to the abdomen wall
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
28 GOH AND LIM

anterior rectus sheath. The patient is instructed to take a deep breath, is coiled around by a plastic Quill guide is advanced into the peritoneal
hold it, and tense the anterior abdominal wall. An 18G  7-cm intro- cavity at 45 angles from the horizontal, directing toward the coccyx.
ducer needle is inserted through the fascia and into the peritoneal cav- The trocar is removed, and the abdomen is filled with about 600 ml of
ity. When this is accomplished, the patient is allowed to breathe filtered air via a separate air insufflation set. The patient is placed in a
normally. Once the presence of the needle in the peritoneal cavity is typical Trendelenbugh position. The peritoneoscope is then inserted
ensured, the cavity is sometimes filled with about 1–2 L of dialysate. through the metal cannula coiled around by the plastic Quill guide,
A guidewire is fed through the needle, and the needle is then with- and the whole assembly is locked and advanced under direct vision
drawn once the guidewire is in position in the peritoneal cavity, leav- (Figure 3). The distal end of the scope is directed parallelly with the
ing the guidewire through the entry point. The patient is again asked anterior abdomen to ensure it enters the air pocket. Once the position
to tense the abdominal muscles and a dilator with a peel-apart sheath is confirmed by noting the smooth surface of the bowel moving with
is introduced over the guidewire to dilate the insertion hole. The dila- respiration, omentum and anterior abdominal wall, the scope is
tor is then removed, leaving the peel-apart sheath in the cavity. The removed together with the metal cannula leaving the plastic Quill
appropriate catheter is soaked in sterile saline, all the air is squeezed guide in place. The plastic guide is dilated and the PD catheter on its
out from the cuff (air has an anti-fibroblast effect) and the catheter is stylet is advanced through the guide (Figure 4). The guide is removed
rinsed with saline. The PD catheter is threaded over the stylet, leaving carefully, ensuring that the catheter does not come out together when
about 1 cm of the distal end empty. The catheter is then advanced the guide is removed. The stylet is then removed from the catheter.
through the sheath (directed posteriorly), and slowly and gently angled Tunnel creation and skin closure are then performed.
about 20 caudally. The stylet is removed, and the catheter is checked
for free flow of dialysate. If the flow is not smooth, the catheter must B. Surgical
be repositioned. Once the catheter is positioned in the desired place,
the sheath is peeled away. A curved tunnel is created and the main 1. Cut-down
incision closed. A tunneling tool is inserted through the exit site and
advanced to the main incision, carefully tracking it to fit the shape of A horizontal incision of the skin is made over the lateral border of
the desired tunnel. The catheter is attached to the tunneling device the rectus sheath (lateral approach) or at the medial border of the rec-
and pulled out through the exit site until the cuff sits snugly under the tus muscle (paramedian approach) and the subcutaneous tissue and
skin, 2 cm away from the exit site. Some centers routinely use fluoros- the rectus are dissected to expose the peritoneal membrane. A 1- to
copy to assist in catheter placement as a modification. 2-cm-long incision is made in the peritoneum and the bowel loops,
omentum, and the peritoneal cavity are identified. The catheter is
2. Peritoneoscopic (one puncture technique designed for nephrolo- then placed into the peritoneal cavity, either between the anterior
gists with local anesthesia) abdominal wall and the omentum, with the tip of the catheter in the
pelvis space just anterior to the rectum. The peritoneum is closed
This procedure provides endoscopic instrumentation with direct around the catheter, using non-absorbable purse-string sutures. The
visualization of the peritoneal cavity for nephrologists and is especially deep cuff sits just external to the entry point through the peritoneum.
useful if adhesions are suspected. A trocar inside a metal cannula that Interrupted sutures are used to close the muscle and subcutaneous

F I G U R E 3 A illustration of
components of Quill assembly
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
GOH AND LIM 29

FIGURE 4 Some of the essential steps of peritoneoscopic peritoneal dialysis (PD) catheter insertion

tissue around the deep cuff. The catheter is then laid over the skin in and cooperate with the nephrologist performing the procedure. The
a curved orientation so that the external segment points lateral and procedure is carried out using Y-Tec® peritoneoscope (Medigroup, Illi-
downwards at the exit. nois, USA) with the use of a VP-210STD disposable pack (Medigroup).
Preferred catheters used are double cuffed coiled PD catheters of
2. Laparoscopic (two puncture techniques designed for surgeons with either 57- or 62-cm length depending on the patient's body habitus.
general anesthesia) Skin preparation for the operation is performed using povidone-
iodine, and the abdomen is draped as per the usual surgical procedure.
Laparoscopy provides a minimally invasive approach with Lignocaine 2% is infiltrated into the skin as local anesthesia, and the
complete visualization of the peritoneal cavity during the catheter procedure is performed as described above. The standard chronic
implantation procedure. Laparoscopic procedures are performed catheter care with povidone-iodine is employed. Patients are routinely
under GA in an operating room environment. Surgical laparoscopy put on a few cycles of manual PD immediately post-op until the PD
uses either a basic or advanced approach to providing PD access. fluid is clear and discharged home the same evening or the next morn-
This technique needs a specially trained laparoscopic surgeon. ing in the absence of complications. Catheter break-in for initiation of
Advanced laparoscopic catheter placement employs proactive adjunc- treatment is usually performed within 2 weeks after insertion of the
tive techniques (such as omentectomy, omentopexy, rectus sheath catheter. If the training of patients and caregivers are delayed,
tunneling, and immobilization of the catheter) that significantly patients will be placed on PD cyclers weekly aiming for a weekly cre-
improve catheter outcomes. atinine clearance of 40–60 L/week/1.73 m2 while waiting for training,
which was usually performed within 2–4 weeks.
It was not our original intention to promote the peritoneoscope
1.4 | Detailed presentation of Y-TEC ® technique alone, but by adopting this technique of PD catheter inser-
peritoneoscopic procedure with laparoscopic tion, we noted several advantages, including its simplicity, which
variations shortens the learning curve for new operators to master the tech-
nique. Also, the technical knowledge of this technique is transferable
Purpose: To learn the basic peritoneoscopic technique. through well-conducted workshops and thus will ultimately provide
This procedure is carried out in a day-care or operating theater. positive, reproducible outcomes and enhance PD penetration.38
Patients are admitted a day earlier and are given a chlorhexidine bath
the evening before the procedure. On the day of the procedure, they
are asked to empty their bladders and prophylactic antibiotic 1.4.1 | Comparison of the three (medical, surgical,
cefuroxime 1.5 g IV will be given. The procedures are performed and peritoneoscope) techniques
under local anesthesia and sedation. A combination of intravenous
midazolam and fentanyl are used. The level of sedation is titrated to The major advantage of the percutaneous method is that it does not
achieve moderate sedation, where the patient is still able to respond require highly skilled surgeons and operating room with its inherence
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
30 GOH AND LIM

long waiting time and needs for GA. The procedure is quick, relatively TABLE 3 Advantages and disadvantages of different implantation
inexpensive and with an experienced operator, the risk of complica- techniques

tion is low. The incidence of the fluid leak around the catheter is par- Advantages Disadvantages
ticularly low with this technique, even when a catheter is used Peritoneoscopy Can be done under Learning curve exists
immediately, as long as the infusion volumes are low.39 The disadvan- local anesthesia Require specialized
tage of the blind method is the potential for complications (including Able to visualize the equipment (Y TEC)
peritoneal cavity Blind puncture
injury to the viscera or bleeding).
Deep cuff secured at Require disposable
Safety is the major advantage of surgical procedures. It is carried rectus muscles VP-210STD pack
out under direct vision and omentum related procedures (if necessary) Can be done by the and air insufflation
and correct positioning of the catheter is possible. This procedure can nephrologist kit
also place any type of catheter. Medical Can be done under Blind puncture
The advantages of peritoneoscope are that it is mainly nephrolo- (Seldinger) local anesthesia Unable to visualize
Can be done at the peritoneal cavity
gist operated and that catheter can be placed in the most suitable
bedside Deep cuff rests on
position under direct vision, while the cost of the surgical technique Low cost rectus muscle
(theater, disposable VP-210STD pack, and air insufflation kit) and the Familiarity with Low pericatheter leaks
initial expense of the peritoneoscope form the major barriers. Fluid procedures

leaks are also more common and healing takes longer following surgi- Open Does not require any Require GA and
laparotomy specialized operating theater
cal technique than after the other procedures.
equipment Limited visualization of
The advantages and disadvantages and their unique characteris-
the peritoneal cavity
tics are summarized below in Tables 3 and 4. Higher postoperative
pain
More pericatheter
leaking
1.4.2 | Recommended technique
Laparoscopy Able to visualize the Require GA and
peritoneal cavity operating theater
We do not favor one technique over the others for the insertion of a Able to perform Learning curve exists
PD catheter. The decision to use any of the techniques outlined above intervention for, for Pain by CO2
depends on a variety of important factors such as familiarity with the example, insufflation
adhesiolysis Higher post-operative
technique, available budget, accessibility of the operating theater/day-
Minimizes the need for pain
care/procedure room, and the existing equipment. From a practical multiple procedures Only limited for use by
perspective, Seldinger's technique is most suitable for a new set-up the surgeon
PD center that has limited resources. Furthermore, most physicians or More pericatheter
leaking
nephrologists are familiar with Seldinger's technique, which makes the
learning curve relatively shorter. On the other hand, if a patient has a Abbreviation: GA, general anesthesia.
previous history of PD peritonitis, a peritoneoscope can be used to
visualize the suitability of peritoneal space before implantation is car-
ried out. Finally, if a patient has previous abdomen surgery in which (tPA) or urokinase may be used to dissolve a fibrin plug. Urokinase
adhesion is deemed to be highly possible, the laparoscopic method 5000 IU diluted with 0.9% saline solution to 40 ml is infused into the
will be preferred as adhesiolysis could be performed at the same set- catheter, and the catheter is clamped for 30–90 min. If required, the
ting if needed. procedure can be repeated with a higher dose of urokinase (10,000 IU
diluted to 40 ml with 0.9% saline). tPA is more expensive (used in a
dilution of 1 mg/ml), and the volume instilled is dependent on the cal-
1.5 | Catheter complications, causes and cures culated volume of the catheter assembly.41 The recovery of flow post
tPA has been reported to be near 100%.42 If the outflow problem is
Purpose: To be aware of possible complications and to avoid and/or due to migration of the PD catheter, it may have to be salvaged, repo-
resolve them. sitioned or replaced.
The usual non-infectious and infectious complications are dis-
cussed below: • Leakage around the catheter

• Outflow problem: Early leaks are usually related to catheter implantation tech-
nique, the timing of PD initiation, dialysate volumes used, and the
Laxative agents are useful to treat constipation related flow strength of abdominal wall tissues. The incidence of pericatheter
issues. If fibrin or clot is observed, heparin 100–500 units/L can be leaks is higher with a midline than with a paramedian site.43 Dialy-
40
added to the dialysate. If that fails, tissue plasminogen activator sate volume should be reduced, or the procedure stopped
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
GOH AND LIM 31

T A B L E 4 Characteristics of
Peritoneoscope versus laparoscope versus open
peritoneoscope versus laparoscope
versus open technique Peritoneoscope Laparoscope Open surgical
Diameter (mm) 2.2 3.10 -
Operator Physician/surgeon Surgeon Surgeon/physician
OT room Yes Definite Yes
Procedure room Yes No Possible
Anesthesia LA GA LA/GA
Poor GA risk Yes No Possible
Anesthetist No Yes No/Yes
Incision/puncture 1 (1–3 cm) 2–3 (1–3 cm) 2 (5 cm)
Operating time (min) 20–30 45 30–45
Insufflation Air CO2 -
Tissue manipulation Minimal More Most
Direct visualization Yes Yes No
Immediate use Yes Maybe No
Leak Minimal Minimal More
Pain ## # Most
Complexity Simple Complex Mix
Length of stay <24 h >24 h 2–3 days
Break-in time ≤1 week ≥2 weeks ≥2 weeks
Previous surgery Yes/no Yes Yes
Obese Yes Yes Yes
Catheter salvage Possible Yes No

Abbreviation: GA, general anesthesia; LA, local anesthesia.

temporarily to allow sufficient time for healing to occur. If the • Cuff erosion
patient is receiving CAPD, a temporary switch to APD in a supine
position is recommended. This tends to be the result of a tunnel being too short for the tun-
nel segment of the catheter, which over time forces the superficial
• Exit site infection cuff out. The extruded cuff can be carefully shaved off.

The presence of redness, pain, swelling, or discharge at the exit • Bowel or visceral perforation
site should be treated as infection, and any discharge should be cul-
tured. First, the area must be cleaned thoroughly, and a local anti- Accidental perforations into the bowel and bladder have been
bacterial agent (such as povidone-iodine) applied daily. Local recognized. Many of these perforations are asymptomatic due to the
treatment alone may not be effective, systemic antibiotics should be small puncturing needle/scope. A majority of these patients can be
added. If the cuff is not involved (the skin over the cuff is not treated medically. Clinical deterioration or increasing peritoneal irrita-
inflamed, squeezing on the cuff produces no discharge or pus) exit tion will require surgical intervention.45
site infection can be treated successfully without removal of the
catheter.44 • Bleeding

• Tunnel infection A common cause of bleeding is laceration of inferior epigastric


arteries. An arterial laceration may occur from needle insertion into
Redness, pain, swelling, and induration over the tunnel are signs the blood vessels, which can be easily detected. In such cases, remov-
of tunnel infection. These do not usually respond to therapy and the ing the needle or other offending agents may be sufficient to control
risk of recurrent peritonitis is high. If the infection does not respond bleeding. Bleeding can also occur from puncture of intra-abdominal
to treatment, the catheter should be removed or replaced through a vessels, though it occurs less frequently. Prompt intervention is
newly created tunnel and antibiotic therapy should be continued for needed and may require surgical ligation through laparoscopy or
at least 2 weeks.44 laparotomy of the affected vessels.46
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
32 GOH AND LIM

• Hernias 1.6.1 | Radiological manipulation

Increased intra-abdominal pressure can cause abdominal Fluoroscopic-guidewire, stiff rod, and aluminum bar manipulations
hernia and hemorrhoids. Decreasing the intra-abdominal pressure have been used to resolve catheter tip migration and extraluminal and
by decreasing volume in a nightly dialysis program may be intraluminal obstructions. The procedures are minimally invasive, do
helpful.47 not require anesthesia, and allow PD to be resumed immediately if
technically successful.52,53
• Pain during dialysate flow:
 At the beginning of inflow improving later:
1.6.2 | Exchange via the percutaneous method
Usually, this is due to hypersensitivity to acidic pH. Measures to
raise the pH of dialysate and ensure the fluid is at a suitable tempera- We have demonstrated successful simultaneous removal and reinser-
ture will be useful.48 tion by PD catheter via a stylet or guidewire, which can be completed
in less than 30 min.54
 At the end of inflow and outflow:
Stylet method
Hydraulic suction of the omentum and a long intraperitoneal A 70-cm stylet is inserted through the old PD catheter into the
segment of the PD catheter due to low implantation can result in peritoneal cavity before the catheter was removed, leaving the end
pelvic wall irritation. Tidal PD or changing to a shorter length of the stylet still within the peritoneal cavity. A new PD catheter is then
tube have been proven to be able to lessen the pain.49 threaded through the stylet (with the curved end straightened) and
then placed into the peritoneal cavity. The internal cuff of the
• Back pain catheter was then placed within the rectus sheath and the external
cuff implanted within the subcutaneous tissue, at least 2 cm away
This is seen frequently in patients undergoing continuous ambula- from the new exit site.
tory peritoneal dialysis and requires that the patient be evaluated for
other medical problems affecting the back. Changing to night-time Guidewire method
50
(supine) dialysis may relieve symptoms in some. A 70-cm guidewire is inserted through the old PD catheter before the
old catheter is removed. Subsequent steps were similar to PD cathe-
• Peritonitis: ter insertion via Seldinger's method. A dilator and a pull-apart sheath
as a single unit were advanced along the guidewire into the peritoneal
If peritonitis presents as an early complication, it should raise the cavity. The new PD catheter is inserted through a pull-apart sheath
possibility of intraoperative contamination. Polymicrobial peritonitis with the guidance of a stylet and placed into its proper position. The
with gram-negative organisms and/or yeasts is most suggestive of internal cuff was placed just above the anterior rectus sheath and the
colonic perforation. If bowel perforation is suspected, the diagnosis external cuff was implanted within the subcutaneous tissue in the
should be confirmed and appropriate surgical intervention with normal fashion.
removal of the infected catheter is recommended.51 The caveat for guidewire guided exchange is that it may not be
able to bypass complete intraluminal blockage from thrombus or
omentum wrap. In such cases, the old PD catheter will not be able to
1.6 | Repositioning of catheter be retracted while keeping the guidewire stationary.

Purpose: To be aware of aspects of catheter salvage or replacement.


When extrinsic compression of the catheter tip by distended 1.6.3 | Surgical manipulation
intraabdominal structures and intraluminal blockage by fibrin/clots
have been excluded, the flow failure can be attributed to either cathe- Direct visualization with endoscopic instrumentation has the advan-
ter tip migration to a location of poor drainage function or obstruction tage of allowing identification of the underlying condition producing
by adherent intraperitoneal tissues. Both conditions may have the catheter flow dysfunction and permits diagnosis-specific manage-
radiologic appearance of a catheter tip displaced from the pelvis while ment. The details of the technique are beyond the scope of the article.
the latter can also occur with a normal pelvic position. Options for However, those who are interested in more detailed descriptions can
restoring catheter flow function include radiologically guided manipu- refer to the article by Crabtree et al.27
lation, laparoscopically-directed interventions, and simultaneous cath- We have outlined the PD catheter malfunction algorithm in
eter replacement. Figure 5.
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
GOH AND LIM 33

F I G U R E 5 Peritoneal dialysis (PD) catheter malfunction algorithm. *, endoscopic salvage via laparoscope or peritoneoscope depending on
available expertise

1.7 | Continuous Quality Improvement and scheme is then restarted. Restart should theoretically be at 0, but one
monitoring tools often restarts at h as the new x axis, so the raising CUSUM chart can
be obtained to represent the learning curve that is typically seen for
PD catheter insertion success rate is known to vary among different trainees.55,56 We defined the acceptable level of performance as a pri-
operators and demands mastery of a steep learning curve. Defining a mary failure rate of <15% (defined as catheter malfunction within
learning curve using a continuous monitoring tool such as a Cumula- 3 months of insertion) and an unacceptable level of performance as a
tive Summation (CUSUM) chart is useful for planning training pro- primary failure rate of >30%.
grams. The evaluation of technical proficiency in a specific operation
is a difficult and complex task. CUSUM is a type of monitoring tool
that has gained acceptance in the medical field. The basic point of the 1.7.1 | Proposed key performance index (KPI)
analysis is to plot the sequential difference of a set of measured
values and to define a target level for those values. With the We recommend the multidisciplinary PD team should meet regularly
establishment of the learning curve, nephrologists, and surgeons can to review and audit the center performance. We suggest the audit
be objectively evaluated for this approach. We applied CUSUM chart- show peg to the following KPIs to ensure the delivery of a
ing to assess the doctor's performance of peritoneoscopic PD cathe- high-quality PD program:
ter insertion. CUSUM chart is a graphical representation of the trend
in the outcome of a series of consecutive procedures.55,56 1. Catheter patency—more than 80% of catheters should be patent
At acceptable levels of performance, the CUSUM curve is flat, at 1 year (censor for death and elective modality changes)
while at unacceptable levels of performance, the curve slopes upward 2. Complications following PD catheter insertion -
and eventually crosses a decision interval, h. When this occurs, the
CUSUM chart indicates unsatisfactory performance. When this hap- • Bowel perforation <1%
pens, the doctor being monitored is required to determine and correct • Significant hemorrhage <1%
the cause of unacceptable performance. The CUSUM monitoring • Exit site infection within 2 weeks of catheter insertion <5%
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
34 GOH AND LIM

• Peritonitis within 2 weeks of catheter insertion <5% 10. Marro  n B, Remo  n C, Perez-Fontan M, Quiro  s P, Ortíz A. Benefits of
• Functional catheter problem requiring manipulation or replacement preserving residual renal function in peritoneal dialysis. Kidney Int.
2008;73:S42-S51.
or leading to technique failure <20%
11. Tam P. Peritoneal dialysis and preservation of residual renal function.
Perit Dial Int. 2009;29(2_suppl):108-110.
12. Alpert MA, Hüting J, Twardowski ZJ, Khanna R, Nolph KD. Continu-
2 | C O N CL U S I O N ous ambulatory peritoneal dialysis and the heart. Perit Dial Int. 1995;
15(1):6-11. doi:10.1177/089686089501500102
13. Arrieta J, Rodríguez-Carmona A, Remo  n C, et al. Peritoneal dialysis is
We have summarized and updated here the catheter types, pre- the most cost-effective alternative for economic sustainability of
procedure work-up, various catheter placement techniques with dialysis treatment. Nefrología (English Edition). 2011;31(5):505-513.
their advantages and disadvantages, post-procedure care, and com- 14. Wang IK, Lu CY, Lin CL, et al. Comparison of the risk of de novo
cardiovascular disease between hemodialysis and peritoneal dialysis
plications. We advocate that nephrologists should play a vital role in
in patients with end-stage renal disease. Int J Cardiol. 2016;218:
the placement of PD catheters. Patients with anticipated problems 219-224.
with PD implantation should be referred for laparoscopic 15. Tenckhoff H, Curtis FK. Experience with maintenance peritoneal
intervention. dialysis in the home. ASAIO j. 1970;16(1):90-95.
16. Twardowski ZJ, Nolph KD, Khanna R, Prowant BF, Ryan LP,
Nichols WK. The need for a “Swan Neck” Permanentl Y bent, arcuate
ACKNOWLEDGEMEN TS
peritoneal dialysis catheter. Perit Dial Int. 1985;5(4):219-223. doi:10.
We would like to acknowledge and thank all the staff who have con- 1177/089686088500500404
tributed to the peritoneal dialysis program and the team that cared for 17. Twardowski ZJ, Prowant BF, Khanna R, Nichols WK, Nolph KD.
PD patients in Hospital Serdang Malaysia. Long-term experience with swan neck Missouri catheters. ASAIO
Trans. 1990;36(3):M491-M494.
18. Khanna R, Izatt S, Burke D, Mathews R, Vas S, Oreopoulos DG.
CONF LICT OF IN TE RE ST Experience with the Toronto Western Hospital permanent peritoneal
All the authors declared no competing interest. catheter. Perit Dial Int. 1984;4(2):95-98. doi:10.1177/
089686088400400211
19. Gokal R, Alexander S, Ash S, et al. Peritoneal catheters and exit-site
ORCID practices toward optimum peritoneal access: 1998 update: (official
Bak Leong Goh https://orcid.org/0000-0002-4644-7743 report from the International Society for Peritoneal Dialysis). Perit
Christopher T. S. Lim https://orcid.org/0000-0003-3623-0484 Dial Int. 1998;18(1):11-33. doi:10.1177/089686089801800102
20. Akyol AM, Porteous C, Brown MW. A comparison of two types of
catheters for continuous ambulatory peritoneal dialysis (CAPD). Perit
RE FE R ENC E S Dial Int. 1990;10(1):63-66. doi:10.1177/089686089001000117
1. Blake PG, Finkelstein FO. Why is the proportion of patients doing 21. Eklund B, Honkanen E, Kyllonen L, Salmela K, Kala A. Peritoneal dialy-
peritoneal dialysis in North America declining? Perit Dial Int. 2001; sis access: prospective randomized comparison of single-cuff and
21(2):107-114. doi:10.1177/089686080102100201 double-cuff straight Tenckhoff catheters. Nephrol Dial Transplant.
2. Mehrotra R, Blake P, Berman N, Nolph KD. An analysis of dialysis 1997;12(12):2664-2666. doi:10.1093/ndt/12.12.2664
training in the United States and Canada. Am J Kidney Dis. 2002;40(1): 22. Eklund BH, Honkanen EO, Kala AR, Kyllönen LE. Peritoneal dialysis
152-160. doi:10.1053/ajkd.2002.33924 access: prospective randomized comparison of the swan neck and
3. Lameire N, Van Biesen W, Dombros N, et al. The referral pattern of Tenckhoff catheters. Perit Dial Int. 1995;15(4):353-356. doi:10.1177/
patients with ESRD is a determinant in the choice of dialysis modality. 089686089501500412
Perit Dial Int. 1997;17:8161-8166. 23. Johnson DW, Wong J, Wiggins KJ, et al. A randomized controlled trial
4. Mendelssohn DC, Mullaney SR, Jung B, Blake PG, Mehta RL. What do of coiled versus straight swan-neck Tenckhoff catheters in peritoneal
American nephrologists think about dialysis modality selection? dialysis patients. Am J Kidney Dis. 2006;48(5):812-821. doi:10.1053/j.
Am J Kidney Dis. 2001;37(1):22-29. doi:10.1053/ajkd.2001.20635 ajkd.2006.08.010
5. Nissenson AR, Prichard SS, Cheng IKP, et al. ESRD modality selection 24. Lye WC, Kour NW, van der Straaten JC, Leong SO, Lee EJC.
into the 21st century. The importance of non medical factors. ASAIO A prospective randomized comparison of the Swan neck, coiled and
j. 1997;43(3):143-150. straight Tenckhoff catheters in patients on CAPD. Perit Dial Int. 1996;
6. Asif A, Byers P, Vieira CF, Roth D. Developing a comprehensive diag- 16(Suppl. 1):S333-S335. doi:10.1177/089686089601601S64
nostic and interventional nephrology program at an academic center. 25. Nielsen PK, Hemmingsen C, Friis SU, Ladefoged J, Olgaard K.
Am J Kidney Dis. 2003;42(2):229-233. doi:10.1016/S0272-6386(03) Comparison of straight and curled Tenckhoff peritoneal dialysis
00646-2 catheters implanted by percutaneous technique: a prospective
7. Thodis E, Passadakis P, Vargemezis V, Oreopoulos DG. Peritoneal randomized study. PeritDial Int. 1995;15(1):18-21. doi:10.1177/
dialysis: better than, equal to, or worse than hemodialysis? Data 089686089501500104
worth knowing before choosing a dialysis modality. Perit Dial Int. 26. Scott PD, Bakran A, Pearson R, et al. Peritoneal dialysis access. Pro-
2001;21(1):25-35. doi:10.1177/089686080102100105 spective randomized trial of 3 different peritoneal catheter prelimi-
8. Prichard S. Treatment modality selection in 150 consecutive patients nary report. Perit Dial Int. 1994;14(3):289-290. doi:10.1177/
starting ESRD therapy. Perit Dial Int. 1996;16(1):69-72. doi:10.1177/ 089686089401400320
089686089601600116 27. Crabtree JH, Shrestha BM, Chow KM, et al. Creating and maintaining
9. Goh BL, Yudisthra MG, Chew SE, Sulaiman MD. Does peritoneal dial- optimal peritoneal dialysis access in the adult patient: 2019 update.
ysis catheter insertion by interventional nephrologist enhance perito- Perit Dial Int. 2019;39(5):414-436. doi:10.3747/pdi.2018.00232
neal dialysis penetration? Semin Dial. 2008;21(6):561-566. doi:10. 28. Abdul Rashid AM, Lim CT. Catheter-related infections and microbio-
1111/j.1525-139X.2008.00478.x logical characteristics in coiled versus straight peritoneal dialysis
1525139x, 2024, 1, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/sdi.13118 by Fielding Graduate University, Wiley Online Library on [29/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
GOH AND LIM 35

catheters in Malaysia. Indian J Nephrol. 31(6):511-515. [cited 2021 43. Helfrich B GB, Pechan BW, Alijani MR, Barnard WF, Rakowski TA,
Sep 28]. Available from: https://www.indianjnephrol.org/ Winchester JF. Reduction in catheter complications with lateral
preprintarticle.asp?id=300522 doi:10.4103/ijn.IJN_238_20 placement. Perit Dial Bull. 1983;3(4_suppl):S2-S4. doi:10.1177/
29. Htay H, Johnson DW. Catheter type, placement, and insertion tech- 089686088300304S01
niques for preventing catheter-related infections in maintenance peri- 44. Li PK, Szeto CC, Piraino B, et al. ISPD peritonitis recommendations:
toneal dialysis patients: summary of a Cochrane review. Am J Kidney 2016 update on prevention and treatment. Perit Dial Int. 2016;36(5):
Dis. 2019;74(5):703-705. doi:10.1053/j.ajkd.2019.07.005 481-508. doi:10.3747/pdi.2016.00078
30. Kanokkantapong C, Leeaphorn N, Kanjanabuch T. The effects of 45. Asif A, Byers P, Vieira CF, et al. Peritoneoscopic placement of perito-
peritoneal dialysis catheter insertion using paramedian versus midline neal dialysis catheter and bowel perforation: experience of an inter-
approach on CAPD patients. J Med Assoc Thai. 2011;94(Suppl 4): ventional nephrology program. Am J Kidney Dis. 2003;42(6):
S52-S57. 1270-1274. doi:10.1053/j.ajkd.2003.08.029
31. Gadallah MF, Pervez A, el-Shahawy MA, et al. Peritoneoscopic versus 46. Mital S, Fried LF, Piraino B. Bleeding complications associated with
surgical placement of peritoneal dialysis catheters: a prospective peritoneal dialysis catheter insertion. Perit Dial Int. 2004;24(5):
randomized study on outcome. Am J Kidney Dis. 1999;33(1):118-122. 478-480. doi:10.1177/089686080402400514
doi:10.1016/S0272-6386(99)70266-0 47. García-Ureña MÁ, Rodríguez CR, Ruiz VV, et al. Prevalence and man-
32. Jwo SC, Chen KS, Lee CC, Chen HY. Prospective randomized study agement of hernias in peritoneal dialysis patients. Perit Dial Int. 2006;
for comparison of open surgery with laparoscopic-assisted placement 26(2):198-202. doi:10.1177/089686080602600214
of Tenckhoff peritoneal dialysis catheter—a single center experience 48. Mactier RA, Sprosen TS, Gokal R, et al. Bicarbonate and
and literature review. J Surg Res. 2010;159(1):489-496. doi:10.1016/ bicarbonate/lactate peritoneal dialysis solutions for the treatment of
j.jss.2008.09.008 infusion pain. Kidney Int. 1998;53(4):1061-1067. doi:10.1111/j.1523-
33. Atapour A, Asadabadi HR, Karimi S, Eslami A, Beigi AA. Comparing 1755.1998.00849.x
the outcomes of open surgical procedure and percutaneously perito- 49. Juergensen PH, Murphy AL, Pherson KA, Chorney WS, Kliger AS,
neal dialysis catheter (PDC) insertion using laparoscopic needle: a two Finkelstein FO. Tidal peritoneal dialysis to achieve comfort in chronic
month follow-up study. J Res Med Sci. 2011;16(4):463-468. peritoneal dialysis patients. Adv Perit Dial. 1999;15:125-126.
34. Voss D, Hawkins S, Poole G, Marshall M. Radiological versus surgical 50. Goodman CE, Husserl FE. Etiology, prevention and treatment of
implantation of first catheter for peritoneal dialysis: a randomized back pain in patients undergoing continuous ambulatory
noninferiority trial. Nephrol Dial Transplant. 2012;27(11):4196-4204. peritoneal dialysis. Perit Dial Int. 1980;1(7):119-123. doi:10.1177/
doi:10.1093/ndt/gfs305 089686088000100703
35. Lee A. Constipation in patients on peritoneal dialysis a literature 51. Kern EO, Newman LN, Cacho CP, Schulak JA, Weiss MF. Abdominal
review. Ren Soc Australas J. 2011;7(3):122-129. catastrophe revisited: the risk and outcome of enteric peritoneal con-
36. Yeo KK, Li Z, Yeun JY, Amsterdam E. Severity of chronic kidney tamination. Perit Dial Int. 2002;22(3):323-334. doi:10.1177/
disease as a risk factor for operative mortality in nonemergent 089686080202200305
patients in the California coronary artery bypass graft surgery 52. Savader SJ, Lund G, Scheel PJ, et al. Guide wire directed manipulation
outcomes reporting program. Am J Cardiol. 2008;101(9):1269-1274. of malfunctioning peritoneal dialysis catheters: a critical analysis.
doi:10.1016/j.amjcard.2008.01.002 J Vasc Interv Radiol. 1997;8(6):957-963. doi:10.1016/S1051-0443
37. Crabtree JH, Fishman A, Huen IT. Videolaparoscopic peritoneal dialy- (97)70693-6
sis catheter implant and rescue procedures under local anesthesia 53. Ozyer U, Harman A, Aytekin C, Boyvat F, Ozdemir N. Correction of
with nitrous oxide pneumoperitoneum. Adv Perit Dial. 1998;14:83-86. displaced peritoneal dialysis catheters with an angular stiff rod. Acta
38. Ng EK, Goh BL, Chew SE, et al. Multicenter analysis on the impact of Radiol. 2009;50(2):139-143. doi:10.1080/02841850802631983
nephrologist initiated catheter insertion program on peritoneal dialy- 54. Azhar AA, Lim CT, Goh BL. The usage of guidewire or stylet in suc-
sis penetration. Semin Dial. 2012;25(5):569-573. doi:10.1111/j.1525- cessful peritoneal dialysis catheter exchange without fluoroscopy or
139X.2012.01051.x peritoneoscope use-the Serdang method. J Clin Transl Nephrol. 2021;
39. Shanmuganathan M, Goh BL, Lim CT. Urgent start intermittent peri- 1:1-5.
toneal dialysis leads to reduction of catheter-related infection and 55. Goh BL, Ganeshadeva Yudisthra M, Lim TO. Establishing learning
increased peritoneal dialysis penetration. Am J Med Sci. 2018;356(5): curve for Tenckhoff catheter insertion by interventional nephrologist
476-480. doi:10.1016/j.amjms.2018.08.004 using CUSUM analysis: how many procedures and in which situation?
40. Sjoland JA, Smith Pedersen R, Jespersen J, Gram J. Intraperitoneal Semin Dial. 2009;22(2):199-203. doi:10.1111/j.1525-139X.2008.
heparin reduces peritoneal permeability and increases ultrafiltration 00536.x
in peritoneal dialysis patients. Nephrol Dial Transplant. 2004;19(5): 56. Goh BL. Nephrologist-initiated peritoneal dialysis catheter insertion
1264-1268. doi:10.1093/ndt/gfh065 Programme: a new paradigm shift. Contrib Nephrol. 2017;189:79-84.
41. Williams AJ, Boletis L, Johnson BF, et al. Tenckhoff catheter replace-
ment or intraperitoneal urokinase: a randomised trial in the manage-
ment of recurrent continuous ambulatory peritoneal dialysis (CAPD)
peritonitis. Perit Dial Int. 1989;9(1):65-67. doi:10.1177/ How to cite this article: Goh BL, Lim CTS. Peritoneal dialysis
089686088900900113
catheter insertion techniques by the nephrologist. Semin Dial.
42. Zorzanello MM, Fleming WJ, Prowant BE. Use of tissue plasminogen
activator in peritoneal dialysis catheters: a literature review and one 2024;37(1):24‐35. doi:10.1111/sdi.13118
center's experience. Nephrol Nurs J. 2004;31(5):534-537.

You might also like