STEP 1 REVIEW COURSE - PART 1

SET 21

SET 21

1. You recommend that your patient, a 51-year-old woman, begin taking calcium and a vitamin
D supplement in order to prevent osteoporosis. What are the steps in the conversion of
vitamin D to its active form in the body? By what mechanism does vitamin D help prevent
osteoporosis?
(FA18 p70) (FA19 p70) (SU p174)

2. What is compartment syndrome, and how is it treated?

(SU p242) (COA p540)

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STEP 1 REVIEW COURSE - PART 1

SET 21
3. Thiazolidinediones (TZDs) increase expression of one type of GLUT receptors—those in
adipose tissue—as one of their antidiabetic actions. Which GLUT receptors would you
expect to find on skeletal muscle and fat?
(FA18 p322) (FA19 p324) (SU p298)

4. Which cell types do not require insulin for the uptake of glucose?
(FA18 p322) (FA19 p324) (SU p174)

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 STEP 1 REVIEW COURSE - PART 1
SET 21
5. Does the notochord become the neural tube?

6. What is the cause of hypertrophic cardiomyopathy?

(FA18 p303) (FA19 p305) (SU p89) (R p569)

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 STEP 1 REVIEW COURSE - PART 1
SET 21
7. During fetal development, what structure traps the inferior poles of the kidney resulting in
a horseshoe kidney? Do patients with horseshoe kidneys have abnormal renal function?
(FA18 p563) (FA19 p567) (SU p144)

8. A 48-year-old woman who has taken oral contraceptive pills for the past 15 years
is concerned because she is not experiencing menopausal symptoms like the rest of
her friends her age. What is the primary reason why menopausal women experience
symptoms? Why might this patient not be experiencing menopausal symptoms? What
symptoms/conditions are attributed to the changes that take place in menopause?
(FA18 p617, 637) (FA19 p622, 641) (SU p208-209, 225)

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STEP 1 REVIEW COURSE - PART 1

SET 21
9. An 18-year-old woman has seasonal allergies. She complains that her eyes water and her
nose runs constantly during the spring. Which cell type is responsible for her symptoms,
and what drug inhibits these cells’ actions? What WBCs descend from the myeloblast
(granulocyte) lineage?
(FA18 p396-397) (FA19 p399-400) (SU p376)

10. A newly married couple is enjoying a honeymoon on a Caribbean beach in Mexico. A few
days into the trip, the two begin complaining of abdominal cramps and watery diarrhea.
They do not have fevers. Which type of Escherichia coli causes the very common “travelers’
diarrhea”?
(FA18 p145) (FA19 p145) (SU p127)

*Page references are as follows:

FA18: First Aid for the USMLE Step 1 2018

FA19: First Aid for the USMLE Step 1 2019
SU: Step-Up to USMLE Step 1 2015
R: Robbins and Cotran Pathologic Basis of Disease, 9th ed. (2015)
Phys: Guyton and Hall Textbook of Medical Physiology, 13th ed. (2016)
H: Harrison’s Principles of Internal Medicine, 19th ed. (2015)
COA: Clinically Oriented Anatomy, 7th ed. (2014)
GG: Goodman and Gilman’s Pharmacological Basis of Therapeutics, 12th ed. (2011)

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