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An examination of clinical outcomes and consequences of nonadherence to medication therapy was
beyond the scope of this review. Published in 2014 Hypotension-induced blindness in haemodialysis
patients: a report of two cases and review of literature S. Bansal A. Ansons M. Vishwanath Semantic
Scholar Semantic Scholar's Logo Figure 1 of 4 Stay Connected With Semantic Scholar Sign Up
What Is Semantic Scholar. It is governed by the peer review system and all original papers are
subject to internal assessment and external reviews. Age was one of the most frequently reported
variable. Kumbala Medicine Case reports in vascular medicine 2022 TLDR This work reports here
what it believes is a unique approach to perform thrombectomy of an occluded graft in a 71-year-old
patient on hemodialysis to avoid placement of tunneled he modialysis catheters and complications
associated withCatheters. At this moment, partial renal function recovery occurred allowing PD
suspension. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and
qualitative measure of the journal's impact. Abiding by the definition of clinical targets for
biochemical measures like pre-dialysis SPL as recommended by international clinical practice
guidelines such as Kidney Disease Improving Global Outcomes (KDIGO), National Kidney
Foundation- Kidney Disease Outcomes Quality Initiative (NKF- KDOQI), or Kidney Health
Australia- Caring for Australasians with Renal Impairment (KHA- CARI) and adapting consistently
measured method to assess medication nonadherence can be a promising step. All rights are
reserved, including those for text and data mining, AI training, and similar technologies. Average life
span in dialysis 256 day (16-786 days). Similarly, disease-related factors include longevity of
haemodialysis, recurrent hospitalization, depressive symptoms and having concomitant illness like
diabetes and hypertension. Table 1 shows the characteristics of included studies. During hospital stay
there were multiple episodes of atrial fibrillation with rapid ventricular response. SJR uses a similar
algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's
impact. A significant number of patients died due to multiple risk factors within 8-9 months.
Vascular access of stating dialysis was 73.8% by catheter and only 32.2% stated with AV
fistula.Conclusion: A large group of patients leave dialysis due to financial or helping personal or
social supportwithin 3-4 months of stating dialysis. Other clinical variables influencing adherence
were having a concomitant illness like diabetes and hypertension, and recurrent hospitalization (
Table 2 ). Study protocol approved by Ethical committeeof institute. Circuits clotting were
interpreted as a consequence of lack of anticoagulation and thrombotic complication of HIT due to
previous exposure to heparin. This partial renal function recovery allowed patient discharge without
the need for renal replacement therapy, but with referral to Nephrology follow-up. Very few studies
found female gender, low education, and unemployment to be significantly associated with
nonadherence. Owing to these inconsistent definitions, wide variation in the reported rates of
nonadherence was observed. Blood cultures with methicillin-resistant Staphylococcus aureus were
performed. Support from healthcare providers had a significant positive effect on adherence to
medication therapy. It is governed by the peer review system and all original papers are subject to
internal assessment and external reviews. Lee Medicine Medicine 2021 TLDR In this large national
database study, vasodilator administration was associated with higher VA primary patency, compared
with controls, in hemodialysis patients, and VDT may have a beneficial effect on maintaining VA
patency in patients undergoing he modialysis. The journal accepts submissions of articles in English
and in Spanish languages. This wide variation in the reported rates of nonadherence was attributed
partly due to heterogeneity in definition and methodology of assessing nonadherence in the studies.
All included studies comprises of ESKD patients receiving treatment at hospital-based outpatient
haemodialysis centres. Funding This research received no funding from any funding agency in the
public, commercial, or not-for-profit sectors.
An examination of clinical outcomes and consequences of nonadherence to medication therapy was
beyond the scope of this review. You can download the paper by clicking the button above.
Bolignano Semantic Scholar Semantic Scholar's Logo Figure 1 of 3 Stay Connected With Semantic
Scholar Sign Up What Is Semantic Scholar. These patients should have immediate discontinuation of
heparin of all sources and administration of a non-heparin anticoagulant, such as argatroban,
danaparoid, fondaparinux or bivalirudin, due to cross-reactivity between heparin products, and
persistent risk of thrombosis even after thrombocytopenia resolves. 11,16,17 However, if there is
bleeding or significant risk of bleeding, anticoagulation might be contraindicated. Funding This
research received no funding from any funding agency in the public, commercial, or not-for-profit
sectors. Expand View on SAGE air.unimi.it Save to Library Save Create Alert Alert Cite Share 19
Citations Highly Influential Citations 1 Background Citations 8 Methods Citations 1 Results
Citations 2 View All Figures and Tables from this paper figure 1 table I table I 19 Citations Citation
Type Has PDF Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced
Papers Sort by Citation Count Sort by Recency Arterial Disease and Vascular Access in Diabetic
Patients S. Identification of risk factors for early mortalityis essential and appropriatemeasure should
take to prevent discontinuation at community and national level. In cases of insufficient information
being ascertained from the title or abstract of a paper, a full copy of the article was obtained and
screened to determine eligibility. Hemodialysis helps control blood pressure and balance important
minerals, such as potassium, sodium, and calcium, in your blood. Degistiricilerdeki Bas?nc
Kay?plar?n?n Iki Boyutlu Bilgisayar Simulasyonlar. Expand 8 PDF Save Anterior Ischaemic Optic
Neuropathy (AION) Associated with Post Dialysis Hypotension E. Tay P. Andreou E. Graham G.
Plant Medicine 2009 TLDR Patients undergoing haemodialysis may be at risk of AION particularly
if they are anaemic and develop post-dialysis hypotension and they should be informed of a small
and unpredictable risk of visual loss. Interventional studies were considered if baseline rates were
provided. For all open access content, the Creative Commons licensing terms apply. Semantic
Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for
AI. Circuits clotting were interpreted as a consequence of lack of anticoagulation and thrombotic
complication of HIT due to previous exposure to heparin. Although younger age was commonly
associated with nonadherence, four studies found nonadherence prevalent in older population as
well. Tunneled catheters pose a higher mortality risk than permanent accesses and are associated
with increased risk of failure of a subsequent fistula. This is an open access article distributed under
the terms of the Creative Commons Attribution License, which permits unrestricted use,
distribution, and reproduction in any medium, provided the original author and source are credited
Data Availability: All relevant data are within the paper and its Supporting Information files.
Patients who receive nephrologic care for over 30 days before starting dialysis have significantly
higher chances of commencing via AV fistula. It is made during a short surgery using one of the two
methods as shown below. She had an acute on-chronic kidney injury stage 3 KDIGO; renal function
did not improve with resolution of septic shock and she was started on dialysis. Fourth case
Caucasian male, 85 years old, diagnosed with rapidly progressive renal insufficiency due to
propylthiouracil induced vasculitis requiring dialysis. Age was one of the most frequently reported
variable. Each patient must have an individualized approach, although heparin and heparin products
must be immediately stopped before a presumptive HD-HIT diagnosis. The laboratory test in our
hospital is the ELISA immune-assay, which is used only for highly suspicious cases as an exclusion
test. Our third objective was satisfied by extracting factors associated with nonadherence and
presenting them in a tabular format according to statistically significant and non-significant findings
across studies per explanatory variables. You need dialysis when you develop end stage kidney
failure, usually by the time you lose about 85 to 90 percent of your kidney function and have a GFR
of. It includes: 1) A factitious chronic disease, which can be severe and disabling; 2) the pilgrimage:
individuals change hospitals, cities or country when their objectives are unsuccessful or discovered;
3) pseudologia fantastica: amazing stories are described with complete certainty. The patient's
profession (nursing) allowed her to carry blood samples to the laboratory, where she supposedly
would add a few drops of urine to raise the levels of creatinine significantly. Transition to peritoneal
dialysis (PD) was decided, and a peritoneal dialysis catheter was inserted; PD was started eleven
days later, complicated by abdominal wall catheter leak.
The prevalence of medication nonadherence varied from 12.5% to 98.6%, with widespread
heterogeneity in measures and definitions employed. His 4T's score was 4 and anti-heparin-PF4
antibodies were positive. Interventional studies were considered if baseline rates were provided. A
number of demographic factors were found to be significantly associated with nonadherence.
Identification of risk factors for early mortalityis essential and appropriatemeasure should take to
prevent discontinuation at community and national level. Baktiroglu F. Yanar I. Ozata G. Oner
Damla Ercan Medicine The journal of vascular access 2016 TLDR Although some authors report
inferior outcomes of vascular access procedures in diabetic patients, there is evidence that most of
the problems encountered can be dealt with by careful patient selection, surgical skill, and
experience. Third case Caucasian female, 73 years old, with stage 3 chronic kidney disease, type 2
diabetes, hypertension, was admitted with septic shock due to urinary tract infection. Days later, she
was withdrawn from the haemodialysis programme. HIT was suspected, as there was no other cause
for thrombocytopenia, 4T score was 5, serological test for HIT antibodies was requested and dialysis
anticoagulation was suspended. She had started dialysis the previous month, and after one week
developed HIT which resolved with suspension of heparin. Outcomes were pooled across studies
using the random-effects model. Blood cultures with methicillin-resistant Staphylococcus aureus
were performed. A significant number of patients died due to multiple risk factors within 8-9
months. Central venous catheter lock was performed with citrate. Nefrologia follows the publication
requirements of the International Committee of Medical Journal Editors (ICMJE) and the
Committee on Publication Ethics (COPE). Studies were excluded if they reported only adherence
outcomes to non-medication interventions such as dialysis exchanges, diet or fluid restrictions, and
exercise; did not clearly define or report rates of nonadherence; or if they were reviews, protocols,
editorials, letters, or dissertations ( Fig 1 ). The journal accepts submissions of articles in English and
in Spanish languages. Total 189 patients who stated dialysis during study period were included.
Bolignano Semantic Scholar Semantic Scholar's Logo Figure 1 of 3 Stay Connected With Semantic
Scholar Sign Up What Is Semantic Scholar. Modeling data suggest that at least 2.9 million people
need dialysis in Asia, which represents a gap in availability of dialysis to the tun. Any discrepancies
were resolved by discussion with the third reviewer (STRZ). Prevalence rates of medication
nonadherence in HD patients. Heparin was suspended and central venous catheter citrate lock was
performed. She was discharged for a Haemodialysis Center within two weeks anticoagulated with
warfarin. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and
qualitative measure of the journal's impact. The Journal publishes articles on basic or clinical research
relating to nephrology, arterial hypertension, dialysis and kidney transplants. We included studies that
evaluated patency, mortality, access infection, and maturation of vascular access in adults requiring
long-term dialysis. Nefrologia follows the publication requirements of the International Committee
of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE). There are
certain criteria that allow us to suspect MS (Table). SJR uses a similar algorithm as the Google page
rank; it provides a quantitative and qualitative measure of the journal's impact.
Heparin was suspended and central venous catheter citrate lock was performed. In the last case
bivalirudin was used as anticoagulant during HCO-HD, which had recently been introduced at our
hospital. Nefrologia follows the publication requirements of the International Committee of Medical
Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE). Table 1 shows the
characteristics of included studies. She checked in at the emergency department reporting fever with
chills, anuria and general discomfort. Expand 21 PDF 1 Excerpt Save. 1 2 3. Related Papers Showing
1 through 3 of 0 Related Papers Figures and Tables 21 References Related Papers Fig. 1. Fundus
photographs right and left eye showing bilateral optic disc swelling. It takes weeks to months before
a fistula is ready for use. AV fistula use is low in the United States but has been improving. Faced
with the evidence, MS was strongly suspected and psychological assessment was requested. In
dialysis patients, citrate anticoagulation, heparin-free dialysis or peritoneal dialysis are options that
must be considered. The diagnosis must be done with caution, because a mistake can be fatal. The
ultrasound showed kidneys and urinary tract of normal size and echogenicity. The high prevalence of
comorbidities of the described patients raises the importance of proper medical approach of HD-
HIT. Nevertheless, the studies included in this review represent a diverse community of patients
from wide geographic locations. The Dialysis Outcomes and Practice Patterns Study (DOPPS)
provides an unparalleled means to examine vascular access practice patterns and guidelines
internationally, with particular attention to associations with mortality risk. Future research should be
directed towards well-designed prospective longitudinal studies developing standard definitions and
validating available measurement tools, while focusing on the role of additional factors such as
psychosocial and behavioural factors in predicting nonadherence to medications. Expand 17 1
Excerpt Save Effect of assistance on peritonitis risk in diabetic patients treated by peritoneal dialysis:
report from the French Language Peritoneal Dialysis Registry. Days later, she was withdrawn from
the haemodialysis programme. Thromboembolic complications develop in 50% of patients. If the 4
T's score is intermediate or high probability, we make a presumptive diagnosis of HIT. 10 The
laboratory tests to confirm HIT include immunologic and functional assays. Transition to peritoneal
dialysis (PD) was decided, and a peritoneal dialysis catheter was inserted; PD was started eleven
days later, complicated by abdominal wall catheter leak. Expand 14 Highly Influential 4 Excerpts
Save Type of vascular access and mortality in U.S. hemodialysis patients. Rajnish K. Dhingra E.
Young T. Hulbert-Shearon S. Leavey F. Port Medicine Kidney international 2001 TLDR This case-
mix adjusted analysis suggests that CVC and AVG are correlated with increased mortality risk when
compared with AVF, both overall and by major causes of death. The trend of increasing use of
catheters in most countries is discouraging. For all open access content, the Creative Commons
licensing terms apply. Expand PDF 2 Excerpts Save Clinical outcomes and quality of life in
hemodialysis diabetic patients versus non-diabetics T. Zeitschrift fur Gefasskrankheiten 2010 TLDR
Haemodialysis access performs worst in patients with diabetes mellitus and in women, and the
benefit of hyperparathyroidism should be interpreted as hypothesis generating. Results: Among 189
ESRD patients on MHD selected with mean age 49.16 years (15-82), male was 60.3% and female
39.7%.Eighty eight 46.5% patient died and 39.15%(74) patient discontinue dialysis due to lack of
financial support or helping assistant or social support. Three (1.6%) patients underwent renal
transplantation and five patients (2.6%) transfer to other dialysis center. For all open access content,
the Creative Commons licensing terms apply. Soleymanian Zeinab Kokabeh Rozita Ramaghi A.
Mahjoub H. Argani Medicine Journal of nephropathology 2017 TLDR Clinical outcomes and health
related quality of life (HRQOL) are much worse in diabetic compared to non-diabetic HD patients
mainly due to more frequent of cardiovascular diseases (CVDs). It is made during a short surgery
using one of the two methods as shown below.
Heparin was suspended and central venous catheter lock was performed with citrate. Due to the time
and resource limitations, we predominantly relied on the full-text articles published in peer-reviewed
journals and did not search conference proceedings for relevant abstracts. Since then dialysis
sessions occurred without complications namely circuit clotting. We will only ask you once and then
you’ll be able to seamlessly download resources as you need. Available data suggest remarkable
heterogeneities, with some countries like Taiwan, Japan and Korea exhibiting well-established HD
systems, high prevalence and universal access to all patients, while low- and low-middle income
countries are unable to provide HD to eligible patients because of high cost and poor healthcare
systems. Many Asian countries have unregulated dialysis units, with poor standards of delivery,
quality control and outcome reporting. All rights are reserved, including those for text and data
mining, AI training, and similar technologies. Support from healthcare providers had a significant
positive effect on adherence to medication therapy. Concerning renal replacement therapy and
anticoagulant therapy individualized approach must be made considering the thrombotic risk of this
situation. The Journal publishes articles on basic or clinical research relating to nephrology, arterial
hypertension, dialysis and kidney transplants. The diagnosis must be done with caution, because a
mistake can be fatal. Although it is a rare disease, its diagnosis is essential for the serious
consequences that it can cause on the patient. The aim of the study was to find out the outcomes of
haemodialysis patients with end-stage renal disease (ESRD) in low Income County. Future research
should be directed towards well-designed prospective longitudinal studies developing standard
definitions and validating available measurement tools, while focusing on the role of additional
factors such as psychosocial and behavioural factors in predicting nonadherence to medications.
Average life span in dialysis 256 day (16-786 days). Clinicians should be aware of different
strategies to promote adherence in this unique patient group, including reducing pill burden, being
aware of potential adverse effects of medications which promote nonadherence, and strategies such
as using combination products. Thromboembolic complications develop in 50% of patients. It takes
weeks to months before a fistula is ready for use. Together with a demanding weekly schedule of
dialysis sessions, increased number of medicines and associated regimen complexity pre-dispose
them at high risk of medication nonadherence. Although a HD-HIT is prothrombotic situation,
account must be taken that renal failure patients are also more prone to hemorrhagic events under
anticoagulation; in fact, simple issues as the safe dose of low-molecular weight heparin for dialysis
patients is not well established. 14,16,17,22 Conclusion In conclusion, HD-HIT must be suspected in
a dialysis patient receiving heparin who present with thrombocytopenia in the first five to fourteen
days after heparin exposure. Are you a health professional able to prescribe or dispense drugs. All
included studies comprises of ESKD patients receiving treatment at hospital-based outpatient
haemodialysis centres. Funding This research received no funding from any funding agency in the
public, commercial, or not-for-profit sectors. In the United States, there is a relatively long average
time between fistula creation and cannulation but significantly worse fistula survival than that seen in
Europe. Fourth case Caucasian male, 85 years old, diagnosed with rapidly progressive renal
insufficiency due to propylthiouracil induced vasculitis requiring dialysis. It is made during a short
surgery using one of the two methods as shown below. Expand View on SAGE air.unimi.it Save to
Library Save Create Alert Alert Cite Share 19 Citations Highly Influential Citations 1 Background
Citations 8 Methods Citations 1 Results Citations 2 View All Figures and Tables from this paper
figure 1 table I table I 19 Citations Citation Type Has PDF Author More Filters More Filters Filters
Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Arterial
Disease and Vascular Access in Diabetic Patients S. Fig 2 shows the prevalence rates of medication
nonadherence in haemodialysis patients according to the three subgroup measures of adherence
(subjective, objective, and biochemical) and also consolidates prevalence rates for similar measures
within the three overarching subgroups. All patients were monthly followed up and appropriate
investigation done. To achieve our first objective, we performed frequency counts of each of the
methods used to assess nonadherence. Furthermore, more than half of the included studies had large
sample sizes above 100 participants.
Warkentin, J. Anderson. How I treat patients with a history of heparin induced thrombocytopenia.
Any discrepancies were resolved by discussion with the third reviewer (STRZ). Outcomes were
pooled across studies using the random-effects model. They are mostly related to the source
publications included in this review. SJR uses a similar algorithm as the Google page rank; it
provides a quantitative and qualitative measure of the journal's impact. Expand 2 PDF Save
Evaluating the Effectiveness of Arterio Venous Fistula Creation Strategy in Diabetics Medicine 2018
TLDR The strategy of primary creation of arteriovenous fistula at the elbow level seems beneficial in
selected groups; it leads to decreasing the number of other reoperations. Expand 750 Highly
Influential PDF 4 Excerpts Save Vascular Access Outcomes in the Elderly Hemodialysis Population:
A USRDS Study M. Chan R. Sanchez H. Young A. Yevzlin Medicine Seminars in dialysis 2007
TLDR The potential benefits derived from AVFs compared with AVGs and central venous catheters
(CVC) may not apply universally and the recommendations of vascular access choice stipulated by
national guidelines may need to be modified for elderly patients. Clinicians should be aware of such
factors so that adherence to medications can be optimised in haemodialysis patients. Age was one of
the most frequently reported variable. No anticoagulation was administered during dialysis, and
multiple episodes of dialysis circuit's clotting occurred, as well as catheter thrombosis. Concerning
renal replacement therapy and anticoagulant therapy individualized approach must be made
considering the thrombotic risk of this situation. Expand 46 Highly Influential PDF 11 Excerpts Save
Salvage of vision after hypotension-induced ischemic optic neuropathy. Susan E. Connolly Kathleen
B. Competing interests: The authors have declared that no competing interests exist. Study protocol
approved by Ethical committeeof institute. Table 1 summarizes these five cases ( Fig. 1 ). Table 1.
Patient characteristics. Patient. Also some PD patients are transplanted or eventually switch to
haemodialysis. Very few studies found female gender, low education, and unemployment to be
significantly associated with nonadherence. Laboratory testing for heparin-induced
thrombocytopenia: a conceptual framework and implications for diagnosis. A quantitative summary
of statistically significant factors and their logical categorisation is presented as Table 2. It is also
imperative to improve education regarding patient’s medication regimens, and provide concise
instructions to prevent confusion. We included studies that evaluated patency, mortality, access
infection, and maturation of vascular access in adults requiring long-term dialysis. Data synthesis on
the factors associated with nonadherence were based on the statistical significance and the direction
(positive or negative) of the association. Blood passes along the tube and into an external machine
that filters it, before it’s passed back into the arm along another tube. Thromboembolic complications
develop in 50% of patients. All patients were monthly followed up and appropriate investigation
done. Heparin was suspended and central venous catheter citrate lock was performed. Future
research should be directed towards well-designed prospective longitudinal studies developing
standard definitions and validating available measurement tools, while focusing on the role of
additional factors such as psychosocial and behavioural factors in predicting nonadherence to
medications. A manual search of the references cited in each publication identified from the database
search was conducted to identify additional relevant articles. The patient's profession (nursing)
allowed her to carry blood samples to the laboratory, where she supposedly would add a few drops
of urine to raise the levels of creatinine significantly.