Modifiable Risk Factors Non-Modifiable Risk Factors

 Voiding Habits  Age

 Fluid Intake  Gender
 Lifestyle (Diet)  Genetics
 Urinary Retention  History of UTI

Hypogastric Pain (Flank Pain)

Fever
Urinary Tract Infection
Legends:
Invasion of Bacteria
Risk Factors

Disease & Signs and Symptoms Bacteria ascend ureters from lower tract

Disease Process
Bacterial Proliferation
Signs and Symptoms
Bacteria start by adhering to the
Bacterial colony irritates urinary epithelium
renal epithelium of the tubules

Dysuria
Inflammatory response initiated

Cytokines releases Inflammation in the Chemokines attract

systematically renal tissues and neutrophils to the
stretching of the renal renal interstitium
capsule
Fever
Neutrophils infiltrates
Flank Pain and die off

WBC in the Urine