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Bsn2 2 Cmca Lec Prelims 1
Bsn2 2 Cmca Lec Prelims 1
[TRANS] LESSON 1: FRAMEWORK FOR MATERNAL AND CHILD HEALTH NURSING CARE
Table No. 3 Infant Mortality: Ten (10) Leading Causes Notes from the discussion by Prof. Lualhati M. Floranda, DNM, RN
NO. AND RATE per 1000 LIVE BIRTHS AND PERCENTAGE
DISTRIBUTION Book Reference – Pillitteri, A. & Silbert-Flagg, J. Maternal & Child
Philippines, 2010 Health Nursing: Care of the Childbearing & Childbearing Family.
Cause Number Rate Percent (8th Edition)
1. Bacterial sepsis of newborn 3,608 2.0 16.1
OUTLINE
I Female Bony Pelvis
A Ilium
B Ischium
i Ischial spines
C Pubic Bones and the Symphysis Pubis
D Sacrum and Coccyx
E Pelvic Canal
II Size and shape of the pelvis
A Pelvic Inlet and Pelvic Outlet
i Pelvic Inlet
ii Pelvic Outlet
III True and False Pelvis ISCHIUM
IV Planes of the Pelvis
• Ischium – thick lower part of the pelvis, formed from 2 fused
A Plane of the Pelvic Cavity
B Plane of the Obstetric Outlet bones - one on either side
C Plane of the Anatomical Outlet
i Consequences of Walking Upright o When a woman is in labor, the descent of the fetal
ii Obstetric Pelvic Axis head as it moves down the birth canal is estimated
V Four Types of Female Pelvis in relation to the ischial spines, which are inward
VI Conjugate projection of the ischium on each side
VII Fetal skull
o If ischial spine is not yet protruding during the
A Fetal Skull Presentation
B Fetal Skull Circumferences internal examination (IE) then the fetus is not yet
C Moulding ready to be delivered
VIII Fetal Skull Bones
A Sutures ISCHIAL SPINES
B Fontanels
C Regions and Landmarks in the Fetal Skull • Ischial spines – smaller and rounder in shape in the woman’s
pelvis than in the man
o On Labor and Delivery Care, you will learn how to
FEMALE BONY PELVIS
feel for the ischial spines to help you estimate how
• Pelvis – hard ring of bone
far down the birth canal the baby’s head has
o Supports and protects the pelvic organs and the
progressed
contents of the abdominal cavity
▪ Pelvic organs include: vagina, cervix, uterus,
bladder, urethra, and rectum
PUBIC BONES AND THE SYMPHYSIS PUBIS
• Pubic bones on either side form the front part of the pelvis
• The two pubic bones meet in the middle at the pubic
symphysis
o Symphysis – a very strong bony joint
• Pubic symphysis – immediately below the hair covered pubic
mound that protects the woman’s external genitalia
o When examining the abdomen of a pregnant
woman, feeling the top of the pubic symphysis with
fingers is an important landmark
o Measuring the height of the uterus from the pubic
symphysis to the fundus (top of the uterus) or fundic
height will enable to estimate the gestational age
• Woman’s pelvis is adapted for child bearing of the fetus
o Wider and flatter shape than the male pelvis ▪ i.e. how many weeks of the pregnancy have
• Pelvis is composed of pairs of bones which are fused together passed, and whether the fetus is growing at the
so tightly that the joints are difficult to see normal rate
ILIUM
• The major portion of the pelvis is composed of 2 bones called
ilium – one on either side of the spinal column and curving
towards the front of the body
• Iliac crest – upper border of the ilium on that side
o Touched when place you hand on either hip
PELVIC OUTLET
• Pelvic outlet is formed by the lower border of the pubic bones
at the front, and the lower border of the sacrum at the back
PELVIC CANAL • Ischial spines point into this space on both sides
• Pelvic Canal – roughly circular space enclosed by the pubic • Figure below shows the dimensions of the space that the
bones at the front, and the ischium on either side at the back; fetus must pass through as it emerges from the mother’s
bony passage through which the baby must pass pelvis.
o This canal has a curved shape because of the o As you look, imagine that you are the birth
difference in size between the anterior and attendant who is looking up the birth canal, waiting
posterior borders of the space created by the to see the fetal head emerging
pelvic bones
SIZE AND SHAPE OF THE PELVIS Table No.1 Sizes of Pelvic Inlet and Pelvic Outlet
• Size and shape of the pelvis is important for labor and delivery PELVIC INLET PELVIC OUTLET
• Well-built healthy women, who had a good diet during their Anterior Sagittal Plane – its
childhood growth period, usually have a broad pelvis that is apex at the lower border of
well adapted for childbirth the symphysis pubis
• Gynecoid Pelvis – round pelvic brim and short, blunt ischial 13 cm wide (on average)
spines and 12 cm from top to Anterior sagittal diameter
o Gives the least difficulty during childbirth, provided bottom from the lower b0rder of the
the fetus is a normal size and the birth canal has no symphysis pubis to the center
abnormal tissue growth causing an obstruction of the bituberous diameter:
• There is considerable variation in pelvis shapes, some of 6 – 7 cm
which create problems in labor and delivery
TRUE AND FALSE PELVIS Anterior sagittal diameter from the lower border of the
• Four bones articulated at four joints symphysis pubis to the center of the bituberous diameter:
o False pelvis – above the pelvic brim and has no 6 – 7 cm
obstetric importance Posterior Sagittal Plane – its apex at the tip of the coccyx
o True pelvis – below the pelvic brim; bone defined
tunnel that the infant must traverse at birth Posterior sagittal diameter from the tip of the sacrum to the
center of the bituberous diameter:
7.5-10cm
SUTURES
• Sutures – joints bet. the bones of the skull
o In the fetus, they can give a little under the pressure
a. Well-flexed head on the baby’s head as it passes down the birth
b. Partially flexed head canal
c. Deflexed head o During early childhood, these sutures harden and
d. Face presentation the skull bones can no longer move relative to one
e. Brow presentation another, as they can to a small extent in the fetus
and newborn
• Face – extends from the upper ridge of the eye to the nose
and chin (lower jaw)
o A face presentation is also a significant risk for the
mother and baby
FONTANELS
• Fontanel – space created by the joining of two or more
sutures
o Covered by thick membranes and the skin on the
baby’s head, protecting the brain underneath the
fontanel from contact with the outside world
o Identification of the 2 large fontanels on the top of Brow Face
the fetal skull helps you to locate the angle at which • Occiput – area bet. the base of the skull and posterior
the baby’s head is presenting during labor and fontanel
delivery
• Fetal fontanel are as follows:
1. Anterior fontanel – aka bregma, a diamond-shaped
space toward the front of the baby’s head, at the
junction of the sagittal, coronal and frontal sutures
▪ Very soft and you can feel the fetal heart beat
by placing your fingers gently on the fontanel
▪ Skin over the fontanel can be seen pulsing in a
new born or young baby
2. Posterior fontanel – aka lambda, a triangular-
shaped and is found toward the back of the fetal
skull. It is formed by the junction of the lambdoid
and sagittal sutures
REFERENCES
MENSTRUATION
• Menstrual cycle (female reproductive cycle) is episodic
uterine bleeding in response to cyclic hormonal changes
• Process that allows for conception and implantation of a new
life
• Length of menstrual cycles differs from woman to woman
• Average length is 28 days (from the beginning of one
menstrual flow to beginning of the next)
o It can be:
▪ As short as 23 days or
▪ As long as 35 days
• The length of the average menstrual flow (termed menses) is HYPOTHALAMUS
o 4-6 days, although women may have period as • Aka the master gland
▪ Short as 2 days or • Release of GnRH (Gonadotrophic Releasing Hormone) or
▪ As long as 7 days (MacKay, 2009) also called LHRH (Luteinizing Hormone-Releasing Hormone)
by the hypothalamus initiates the menstrual cycle
PURPOSE OF MENSTRUATION • When the level of estrogen (produce by the ovaries) rises,
1. To bring an ovum to maturity release of the hormone is repressed, and menstrual cycles do
2. Renew a uterine tissue bed that will be responsible for not occur
the ova’s growth should it be fertilized o The principle that birth control pills use to eliminate
menstrual flow
NORMAL CHARACTERISTICS OF MENSTRUATION • During childhood, hypothalamus is apparently so sensitive to
the small amount of estrogen produced by the adrenal
Table No.1 Characteristics of Normal Menstrual Cycles glands that release of the hormone is suppressed
CHARACTERISTICS DESCRIPTION • Beginning with puberty, hypothalamus becomes less
Beginning (Menarche) Average age at onset, 12.4 sensitive to estrogen feedback; this results in the initiation
years; average range 9-17 every month in females of the hormone GnRH
years o GnRH is transmitted from the hypothalamus to the
Interval bet. Cycles Average, 28 days; cycles of anterior pituitary gland and signals the gland to
23-25 days not unusual begin producing the gonadotropic hormones
Duration of Menstrual Flow Average flow, 2-7 days; Follicle-Stimulating Hormone (FSH) and Luteinizing
ranges of 1-9 days not Hormone (LH)
abnormal • Because production of GnRH is cyclic, menstrual periods is
Amount of Menstrual Flow Difficult to estimate; average also cycle.
30-80mL per menstrual
period; saturating pad or
tampon in less than an hour is
heavy bleeding
Color of Menstrual Flow Dark red; a combination of
blood, mucus, and
endometrial cells
Odor Similar to that of marigolds
WHAT MAY ALTER MENSTRUATION
1. Diseases of the hypothalamus that cause deficiency of
this releasing factor can result in delayed puberty
OVARY
• By day 14, before the end of a menstrual cycle (the midpoint
of a typical 28-day cycle), the ovum has divided by mitotic
division into two separate bodies
1. Primary oocyte – contains the bulk of the cytoplasm
2. Secondary oocyte – contains so little cytoplasm
that it is not functional
• Structure also has accomplished its meiotic division, reducing
its no. of chromosomes to the haploid (having only one
member of a pair) number of 23
• After an upsurge of LH from the pituitary, prostaglandins are
released and the graafian follicle ruptures
• The ovum is set free from the surface of the ovary, a process
termed ovulation
• It is swept into open end of a fallopian tube
o Teach women that ovulation occurs on
approximately the 14th day before the onset of the
next cycle, not necessarily at a cycle’s midpoint
• After the ovum and the follicular fluid have been discharged
from the ovary, the cells of the follicle remain in the form of a
hollow, empty pit
o FSH has done its work at this point and now
decreases in amount
ISCHEMIC PHASE
• If fertilization does not occur, the corpus luteum in the ovary
begins to regress after 8 to 10 days
• As it regresses, the production of progesterone and estrogen NON-FERTILE TRANSITIONAL FERTILE
decreases Only dots and Some fern A lot of ferning
• W/ the withdrawal of progesterone stimulation, the some lines appear patterns start to patterns appear
endometrium of the uterus begins to degenerate (at appear
approximately day 24 or day 25 of the cycle) • When progesterone is the dominant hormone, as it is just after
• Capillaries rupture, with minute hemorrhages, and the ovulation, when the luteal phase of the menstrual cycle is
endometrium sloughs off beginning, a fern pattern is no longer discernible
• Cervical mucus can be examined at midcycle to detect
MENSES PHASE whether ferning, which suggests a high estrogen surge, is
• Menses is composed of: present
1. Blood from the ruptured capillaries • Women who do not ovulate continue to show the fern
2. Mucin from the glands pattern throughout the menstrual cycle (i.e., progesterone
3. Fragments of endometrial tissue levels never become dominant), or they never demonstrate
4. Microscopic, atrophied, and unfertilized ovum it because their estrogen levels never rise
• A menstrual flow contains only approximately 30-80mL of
blood SPINNBARKEIT TEST
o It seems like more, it is because of the • At the height of estrogen secretion, cervical mucus not only
accompanying mucus and endometrial shreds becomes thin and watery but also can be stretched into long
• Iron loss in a typical menstrual flow is approximately 11mg strands
o This is enough loss that many women need to take • This stretchability is in contrast to its thick, viscous state when
a daily iron supplement to prevent iron depletion progesterone is the dominant hormone
during their menstruating years o A woman can do this herself by stretching a mucus
sample between thumb and finger, or it can be
tested in an examining room by smearing a cervical
REFERENCES
PHASE 4: RESOLUTION
• Occurs after orgasm and allows the muscle to relax, blood
pressure to drop and the body to slow down from its excited
state
▪ Predicting your first fertile day (based on Table CERVICAL MUCUS METHOD
no.1) • aka Billings method
▪ Shortest cycle is 26 days – 18 =8 • Based on the changes that occurs on the cervical mucus
▪ If day one was the 4th day of the month, the during the menstrual cycle
day you will mark X will be the 11th o Avoid intercourse when mucus is becoming more
▪ That’s the first day you’re likely to be fertile. So clear, elastic and slippery
on that day, you should start abstaining from ▪ First Half of the Cycle – estrogen level is high –
sex or start using a cervical cap. thin mucus – excellent survival for sperm
▪ Second Half of the Cycle – progesterone level
2. To predict the last fertile day in your current cycle is high – thick mucus – poor survival for sperm
o Find the longest cycle in your record • Monitoring cervical-mucus changes to predict when
o Subtract 11 days from the total no. of the days ovulation occurs
o Count that number of days from day one of your • As ovulation approaches, the cervical mucus thins and
current cycle, mark that day with an X becomes increasingly elastic and transparent
o Include day one when you count • Cervical Mucus – normally cloudy and tacky, it becomes
o The day marked X is the last fertile day clear and slippery (similar to egg whites) before ovulation
▪ Predicting you last fertile day (based on Table o It will also be stretchy bet. your fingers
no.1) (Spinnbarkeit).
▪ Longest day is 30 days – 11 = 19 o To use these changes for birth control, you must be
▪ If day one was the 4th day of the month, the religious in observing YOUR pattern changes
day you will mark X will be the 22nd
▪ That’s the last day you’re likely to be fertile
during your current cycle
▪ So you may start to have unprotected vaginal
intercourse after that day
8 9 10] 11 12 13 14
Safe Day Safe Day Safe Day
15 16 17 18 19 20 21
SYMPTOTHERMAL METHOD
22 [23 24 25 26 27 28 • Combines the cervical mucus and BBT methods
Safe Day Safe Day Safe Day Safe Day Safe Day Safe Day
• Woman takes her temp. daily watching for the rise in temp.
29 30 1 2 3 4 5 that marks ovulation
Safe Day Safe Day Safe Day Safe Day Safe Day Safe Day Safe Day o Also analyzes her cervical mucus every day
Start of Period: Safe Days: [ ] Unsafe Days: observes for other signs of ovulation such as
mittelschmertz (midcycle abdominal pain)
• In this example, the 11th through 22nd are unsafe days • Couple must abstain from intercourse until 3 days after the
o All the others are safe days rise in temperature or the 4th day after the peak of mucus
• This method is ineffective if: change, because these are the woman’s fertile days
o Woman has an irregular menstrual cycle • Symptothermal method is more effective than either the BBT
o All cycles are shorter than 27 or the cervical mucus method alone (ideal failure rate, about
o Woman has no self-control 2%)
o Woman is lazy to take a monthly record of
menstrual cycle OVULATION DETECTION
• Use of an over-the-counter ovulation detection kit
BASAL BODY TEMPERATURE METHOD • These kits detect the midcycle surge of luteinizing hormone
• Just before the day of ovulation, a woman’s basal body (LH) that can be detected in urine 12-24hrs before ovulation
temperature (BBT), or temperature of her body at rest, falls • Such kits are 98% - 100% accurate in predicting ovulation
about 0.5 F • Although they are fairly expensive, use of such kit in place of
o At the time of ovulation, her BBT rises a full degree cervical mucus testing make this form of natural family
because of the influence of progesterone planning more attractive to many women
o This higher level is then maintained for the rest of • Combining it with assessment of cervical mucus is becoming
menstrual cycle the method of choice for many families using natural family
o This pattern is the basis of the BBT method of planning
contraception
• Body temp. measured immediately after awakening and
before any physical activity has been undertaken
o In women, ovulation causes an increase of 0.5-1 F
(0.25-0.5 C) in basal body temperature
o Monitoring of BBT is one way of estimating the day
of ovulation
EFFECT ON PREGNANCY
• If a woman taking an estrogen/progestin (COCs) suspect
that she is pregnant, she should discontinue taking any more
pills she intends to continue the pregnancy
• High levels of estrogen or progesterone might be teratogenic
to a growing fetus, although the actual risk thought to be no
higher than normally occurs
• Use by adolescent
o Usually recommended that adolescent girls have
well-established menstrual cycles for at least 2yrs
before beginning COCs
o This reduces the chance that the estrogen content
will cause permanent suppression of pituitary- • To be folded on itself and inserted into vagina
regulating activity • Impregnated sex steroid is absorbed into systemic circulation
to prevent ovulation
TRANSDERMAL ROUTE
• Transdermal contraception – refers to patches that slowly but
continuously release a combination of estrogen and IMPLANTATION
progesterone • 5 subdermal implants, rods the size of pencil lead are
• Patches are applied each week for 3 weeks embedded just under the skin on the inside of the upper arm
• No patch is applied the 4th week • Implants are inserted w/ use of a local anesthetic, during the
o During the week on which the woman is patch free, menses or no later than day 7 of the menstrual cycle, to be
a menstrual flow will occur certain that the woman not pregnant at the time of insertion
o After the patch-free week, a new cycle of 3 weeks • Can be inserted immediately after an elective termination of
on/1 week off begins again pregnancy or 6 weeks after the birth of a baby
o Efficiency is equal to COCs • Failure rate is less than 1%
▪ May be less effective in women who weigh • At the end of 3-5 years, the implants are removed under
more than 90kg (198lbs) local anesthesia ( a quick minutes-only procedure)
• They have the same risk for thromboembolic symptoms as
COCs
• Patches may be applied to one of the ff. four areas:
1. Upper outer arm
2. Upper torso (front or back, excluding the breasts)
3. Abdomen
4. Buttocks
DIAPHRAGM
• Proper size should be used
• Held in position at least for 6hrs
• Used with spermicidal jelly
• Should be left in place for at least 6-8hrs after intercourse
SPERMICIDES
• Chemical barrier preventing pregnancy by killing sperm or
neutralizing vaginal secretions
• Available in a variety of forms like:
1. Creams • Apply jelly to the rim and center of the diaphragm
2. Gels
3. Melting suppositories CERVICAL CAP
4. Foaming tablets • Similar to diaphragm, except it fits snugly over the cervix
5. Aerosol foams • Maybe left in place for 48hrs
6. Vaginal contraceptive film • Tends to be difficult for women to insert and remove
• Most common spermicidal agents:
o Nonoxynol-9
o Octoxynol-9
• Allergic response is possible
• Must be applied with each act of sexual intercourse;
interferes with spontaneity
• Safe for breastfeeding mothers
• May be irritating; messy
TERMINAL METHODS
• Male sterilization
• Female sterilization
MALE STERILIZATION
• Vasectomy
• Severs the vas deferens
• Simple procedure
• Does not interfere with erectile function
FEMALE STERILIZATION
• Tubal ligation
• Severs the fallopian tube
• Involves general anesthesia
OUTLINE
I Genetic Disorders
A Gene Therapy
II Gregor Johann Mendel
III Introduction to Genetics
IV Mendelian Inheritance: Dominated Recessive Patterns
A Autosomal Dominant Disorders
i Punnett Square
B Autosomal Recessive Inheritance
C X-Linked Dominant Inheritance o New combinations of genes occur in sexual
D Y-Linked Inheritance reproduction due to fertilization from 2 parents
i Multifactorial (Polygenic) Inheritance • Cytogenetics – study of chromosomes by light microscopy
V Process of Determining the Sex of the Baby and the method by which chromosomal aberrations are
A Genetic Transmission identified
VI Genetic Counseling Table No.1 Genetics Term
TERM DESCRIPTION
GENETIC DISORDERS Gene Unit of heredity; a section of DNA sequence
• Inherited or genetic disorders – disorders that can be passed encoding a single protein
from one generation to the next Genome Entire set of genes in an organism
o Results from some disorder in gene or chromosome Alleles Two genes that occupy the same position on
structure and occur in 5% to 6% of newborns homologous chromosomes and that cover
• Genetic disorders may occur at the moment an ovum and the same trait
sperm fuse or even earlier, in the meiotic division phase of the Homozygous Having identical genes (one from each
gametes (ovum and sperm) parent) for a particular characteristic
• Some genetic abnormalities are so severe that normal fetal Heterozygous Having 2 different genes for a particular
growth cannot continue past that point characteristic
• Some do not affect life in utero, so the result of the disorder Dominant Allele of a gene that masks or suppresses the
becomes apparent only at the time of fetal testing or after expression of an alternate allele; trait appear
birth in the heterozygous condition
Recessive Allele that is masked by a dominant allele;
GENE THERAPY doe not appear in the heterozygous
• In the near future, it may be possible not only to identify condition, only in homozygous
aberrant genes for disorders this way but also to insert healthy Difference Between Dominant and Recessive Genes
genes in their place using stem cell implantation Dominant is always expressed when present. Recessive is only
• Gene replacement therapy – encouraging in the treatment expressed when no dominant genes are present.
of blood, spinal cord, and immunodeficiency syndromes Genotype Genetic makeup of an organisms; refers to his
• Women can arrange to have a newborn’s cord blood frozen or her actual gene composition
and banked to be available for bone marrow or other cell Phenotype Physical appearance of an organism
transplantation procedures in the future (genotype + environment); refers to his or her
o As stem cells from replacement therapy can be outward appearance or the expression of
obtained from menstrual blood, this also may be a genes
future contribution source
Genome Complete set of genes present (about 50,000
– 100,000)
GREGOR JOHANN MENDEL Normal genome is abbreviated as 46XX
• Known as the father of modern genetics (female) or 46XY (male) – designation of the
• Austrian Monk, born in Czech Republic in 1822 total no. of chromosomes plus a graphic
o Son of peasant farmer, studied Theology and was description of the sex chromosomes present
ordained priest Order St. Augustine Karyotype “general” form; number and appearance oof
o Went to the university of Vienna, where he studied chromosomes in the nucleus of a eukaryotic
botany and learned the Scientific Method cell
• Worked w/ pure lines of peas for 8yrs Complete set of chromosomes in a species or
o Prior to Mendel, heredity was regarded as a an individual organism
“blending” process and the offspring were a
“dilution” of the different parental characteristics
INTRODUCTION TO GENETICS
• Genetics – branch of biology that deals with heredity and
variation of organisms
• Chromosomes – carry the hereditary information (genes)
o Each individual consists of 46 of chromosome
▪ 23 (father) + 23 (mother)
o Chromosomes and genes occur in pairs
(homologous / non-homologous chromosome)
▪ Homologous Chromosome – same genes
▪ Non-homologous chromosome – different
genes
PUNNETT SQUARE
• Useful tool to do genetic crosses
• For a monohybrid cross, you need a square divided by 4
• Punnett square is used to predict the genotypes and
phenotypes of the offspring
25% 25%
25% 25%
A A
Father h = “healthy” gene Father
H d d = disease gene, recessive in this x y
Ẋx = disease state
H HH Hd example Ẋ Ẋx Ẋy
Mother dd = disease Mother
Ẋy = disease state
d dH dd Hd or dH = carrier x xx xy
Figure 7. Sex-linked inheritance: Sex-linked Dominant
B
Father h = “healthy” gene B
H H d = disease gene, recessive in this Father
H HH HH example x y
Mother dd = disease
ẋx = carrier
X Xx Xy ẋy = disease state
d dH dH Hd or dH = carrier Mother
ẋ ẋx ẋy
C C
Father h = “healthy” gene Father
H H d = disease gene, recessive in this ẋ y xy = normal state
d dH dH example ẋx = carrier state
Mother dd = disease X Xẋ xy
d dH dH Mother ẋy = disease state
Hd or dH = carrier x Xẋ xy
Figure 8. Sex-linked inheritance: Sex-linked Recessive
D
Father h = “healthy” gene
d H d = disease gene, recessive in this
d dd dH example
Mother dd = disease
d dd dH Hd or dH = carrier
E
Father h = “healthy” gene
d d d = disease gene, recessive in this
d dd dd example
Mother dd = disease
d dd dd Hd or dH = carrier
Figure 5. Autosomal recessive inheritance Figure 9. Family Genogram: X-Linked Recessive Inheritance
Y-LINKED INHERITANCE
• Although genes responsible for features such as height and
tooth size are found on the Y chromosome, tall stature and
perhaps aggressive personality are the only consistent
phenotypic features associated w/ having an extra Y
chromosome (Karyotype 47XYY)
GENETIC COUNSELING
• Can result in making individua feel “well” or free of guilt for
the first time in their lives if they discover that the disorder, they
were worried about was not an inherited one but was rather
a chance occurrence
• Counseling results in informing individuals that they are
carriers of a trait that is responsible for a child’s condition
• Even when people understand that they have no control
over this, knowledge about passing a genetic disorder to a
child can cause guilt and self-blame
• Marriages and relationships can end unless both partners
receive adequate support
REFERENCES
FERTILZATION
• aka conception and impregnation
• union of an ovum and a spermatozoon • Spermatozoa move through the cervix and the body of the
• Occurs in the outer third of fallopian tube, the ampullar uterus and into the fallopian tubes, toward the waiting ovum
portion by the combination of movement by their flagella (tails) and
• Usually, one of a woman’s ova will reach maturity each uterine contractions
month • Sperm must undergo 2 processes before fertilization:
1. Sperm capacitation
2. Acrosomal reaction
ACROSOMAL REACTION
• Follows capacitation
• Acrosomal covering of the head od the sperm contains
hyaluronidase
d. Morula – solid ball of cells produced by 16 or so blastomeres,
• As millions of sperms surrounds the ovum, they deposit
called the “travelling” form because it is in this form when it
amounts of hyaluronidase in the corona radiata, (the outer
migrates through the fallopian tube and reaches the uterine
layer of the ovum), which allows the sperm head to
cavity about 3-4 days after ovulation
penetrate the ovum
• The cavity enlarges and pushes the morula cells into an outer
layer cell called the trophoblast
CHORIONIC VILLI
• Once implantation is complete, the trophoblastic layer of
cells of the blastocyst begins to mature rapidly
• As early as the 11th or 12th day, miniature villi that resemble
probing fingers, termed chorionic villi, reach out from the
single layer of cells into the uterine endometrium to begin
formation of the placenta
• At term, almost 200 such villi will have formed • Placenta is formed by the union of the chorionic villi and
decidua basalis
• Decidua – the endometrium in pregnancy, thickens in
pregnancy w/ depth of 5-10cm
a. Decidua Basalis – portion of the decidua directly
beneath the site of implantation
b. Decidua Capsularis – portion overlying the developing
ovum, separates ovum from the rest of the uterine
cavity, most prominent by 2nd month
c. Decidua Vera/Parietalis – lines for the remainder of the
uterus
UMBILICAL CORD/FUNIS
• Umbilical cord – formed from the fetal membranes (amnion
and chorion) and provides a circulatory pathway that
connects the embryo to the chorionic villi of the placenta
• Its function is to transport O2 and nutrients to the fetus from
the placenta and0 to return waste products from the fetus to
the placenta
• Layers of the Decidua Basalis and Decidua Vera • Size – 53cm (21in) in length at term and about 2cm (3/4in)
a. Zona Compacta – uppermost/surface layer made up of thick
compact cells • The bulk of the cord is a gelatinous mucopolysaccharide
b. Zona Spongiosum – middle, spongy layer, w/ glands and called Wharton’s jelly which gives the cord body and
small blood vessels prevents pressure on the vein and arteries that pass through
c. Zona Basalis – lower most/basal layer, this layer remains it
after delivery/placenta separation • Outer surface is covered w/ amniotic membrane
• AVA – contains only 1 vein (carrying blood from the placental
villi to the fetus) but 2 arteries (carrying blood from the fetus
back to the placental villi
o No. of veins and arteries in the cord is always
assessed and recorded at birth bec. about 1-5% of
infants are born w/ a cord that contains only single
vein and artery
12 WEEKS
• Placental fully formed and functioning
o Kidneys develop; secrete urine
o Centers of ossification in most bone
o w/ sucking and swallowing
o sex distinguishable
o Fetal heart tone detected by ultrasound
• 12th Week of Gestation
o Toes and fingers already have nail beds
o Faint fetal movements are starting
o Early reflexes are present
ORIGIN & DEVELOPMENT OF ORGAN SYSTEMS o Tooth buds are forming
o Formation of bone ossification centers initiate
4 WEEKS o Genital is already recognizable through its
• All systems in the rudimentary form appearance
o Beginning formation of eyes, nose, GIT o Urine secretion begins but is not yet evident
o Heart chambers forms o Heartbeat could be detected by Doppler
o Heart beating (14 days)
o w/ arms and leg buds
• 4th Week of Gestation
o Spinal cord is formed and fused at the midpoint
o Head folds forward and is prominent
o Back is bent, which makes the head almost touch
the tail
o A prominent bulge appears which would later form
as the heart
o Lateral wings, the body, folds forward and fuse at
midline
o Arms and legs are budlike structures
o Eyes, ears, and nose are barely recognizable
16 WEEKS
• More human appearance
o Quickening – multigravida
o Meconium in bowels
o External genitalia obvious
o Scalp hair develops
o Formed eyes, nose, ears
o Fetal Heart Tone by fetoscope
• 16th Week of Gestation
o An ordinary stethoscope could detect the fetus’
8 WEEKS heart beat
• Head large in proportion to the body o Lanugo (hair) has started to form
o Neuromuscular development o Pancreas and liver are forming
o Some movements o Urine is present in the amniotic fluid
o Rapid brain development o Fetus starts to swallow the amniotic fluid
o External genitalia appear o Ultrasound could determine the sex of the fetus
• 8th Week of Gestation
o Organogenesis is achieved and complete
o Heart already developed septum and valves and is
beating rhythmically
o Arms and legs have developed
o Facial features are noticeable
o Genital starts to form but is not yet recognizable
o Fetal intestine is rapidly growing
o Results of an ultrasound would show a gestational
sac which confirms pregnancy
20 WEEKS 32 WEEKS
• With vernix caseosa and downy lanugo • Subcutaneous fats begin to deposit
o Quickening stronger, felt by primigravida o Skin is smooth and pink
o Fetal Heart Tone by stethoscope o More reflexed present
o Bones hardening o w/ iron and calcium storage
o good chance of survival if delivered
• 32nd Week of Gestation
o Subcutaneous fat is deposited
o Fetus responds to sounds outside the mother’s body
through movements
o Active Moro Reflex is present
o Iron stores are starting to develop
o Fingernails are starting to grow
24 WEEKS
• Body well proportioned
o Hearing established
o Eyebrows, eyelashes recognizable
o When born, may breathe, but usually doesn’t
• 24th Week of Gestation 36 WEEKS
o Lung surfactant begins to develop • Lecithin/sphingomyelin ratio 2:1
o Meconium is present at the rectum o Nails firm
o Eyebrows and eyelashes are distinguishable o w/ definite sleep/wake pattern
o Eyelids can now open o lanugo disappearing
o Pupils react to light o survival same as term
o Fetus has reached the age of viability, wherein they • 36th Week of Gestation
could survive externally if cared for in a modern o Depositions of iron, carbohydrate, calcium, and
intensive facility glycogen stores are in the body
o Additional subcutaneous fats are deposited
o One or two creases are present at the sole of the
foot
o Lanugo starts to diminish
o Some babies turn and assume a vertex presentation
28 WEEKS
• Viable, immature if born at this time
o Surfactant production begins
o Body is less wrinkled 40 WEEKS
o With iron storage • Full term w/ good muscle tone & reflexes
o Nails appear o Little lanugo
o Pupillary membranes have just disappeared from o If male, test in scrotum
the eyes o With other characteristics features of the new born
• 28th Week of Gestation • 40th Week of Gestation
o Surfactant is demonstrated in the amniotic fluid o Fetus now kicks very actively and hard enough to
o Alveoli are starting to mature cause discomfort
o Testes descend into the scrotal sac o The fetal hemoglobin is being converted to adult
o Retinal blood vessels start to form but are highly hemoglobin
susceptible to damage o Vernix caseosa is fully formed
o Fingernails extend to the fingertips
o Soles of the feet have creases that cover at least
2/3 of the surface
BARTHOLOMEW’S RULE
ASSESSMENT OF FETAL GROWTH AND DEVELOPMENT • Estimation of AOG by the relative position of the uterus in the
abdominal cavity
NAEGELE’S RULE o 3rd lunar month – fundus is palpable slightly above
• Calculations of expected date of confinement (EDC) or the symphysis pubis
estimated date of delivery (EDD) o 5th lunar month – fundus is at the level of the
• Formula: umbilicus
o If patient LMP is Jan-Mar, then: o 9th lunar month – fundus is below the level of the
▪ +9, +7, +0 xiphoid process
o If patient LMP is Apr-Dec, then: • This determines the relative position of the uterus in the
▪ -3, +7, +1 abdominal cavity
ULTRASOUND
• Ultrasound – transducer on abdomen transmits sound waves
that show fetal image on screen
a. Done as early as 5 weeks to confirm pregnancy,
gestational age
b. Multiple purposes – to determine position, number,
measurement of fetus(es) and other structures
(placenta)
c. Client must drink fluid prior to test to have full bladder to
ASSESSING FETAL WELL-BEING
assist in clarity of image
d. No known harmful effects for fetus or mother
e. Non-invasive procedure
FETAL MOVEMENT
• Fetal movement that can be felt by the mother (quickening)
occurs at approximately 18-20 weeks of pregnancy
• Peaks in intensity at 28-38 weeks
• Fetal movement should be assessed when there is
quickening (at 24 months age of gestation onwards)
• Two schools of thought:
1. Cardiff Count to Ten
2. Sandovsky Method
ULTRASOUND
• Confirmation of pregnancy and fetal presentation
• Evaluation of fetal heartbeat and fetal respiration
• Identification of more than one embryo or fetus
• For examination of anatomical fetal structures
• Estimate gestational age, fetal weight, and growth
• Location of the placenta and amniotic fluid volume
REFERENCES