BSN 3-A (GROUP 7)

Ramirez, Mary Kate

Ramulte, Vevienne Aizel
Rapatan, Christan Anthony
Robredillo, Reena Grace

March 12, 2024

 CLINICAL MANIFESTATIONS PATHOPHYSIOLOGY
Systemic Lupus Erythematosus (SLE)
Fever
Fatigue 👇🏻
Skin rashes Immune system recognizes nuclear components as foreign
Joint pain and swelling 👇🏻
Baldness Immune system produces antibodies against nuclear antigen
RISK FACTORS Anemia, neutropenia, thrombocytopenia 👇🏻
Pericarditis Formation of antigen-antibody complexes
Genetic Lupus nephritis 👇🏻
Gender Complexes get trapped in capillaries of visceral structures
Ethnicity 👇🏻
Antibodies destroy host cells
Environmental
Hormones
👇🏻
Genetic factors play a role in SLE development
👇🏻
Hormonal factors, particularly estrogen, may contribute to the
COMPLICATIONS body's response
Skin scarring Pregnancy
👇🏻
Environmental triggers like cigarette smoke, UV rays, certain
Joint deformities complications medications, viral infections, and stress are implicated
Kidney failure Hip destruction 👇🏻
Stroke Cataracts Immunoregulatory disturbance leads to clinical manifestations
👇🏻
Heart attack Bone fractures
SYSTEMIC Combination of genetic, immunologic, hormonal, and
environmental factors lead to SLE symptoms
PATIENT TEACHING LUPUS 👇🏻
Symptoms of SLE include inflammation, tissue damage, and
ERYHTHEMATOSUS organ dysfunction
Instruct in the opportunities for
support groups in the community or
👇🏻
on reputable internet websites. (SLE) Gradual progression of disease can lead to severe
complications and organ failure.
Stress the importance of not altering
the dose or suddenly stopping the
medication.
NURSING INTERVENTIONS
Instruct in lifestyle activities that can
Administer prescribed medication (NSAID and salicylates)
help reduce flare-ups. Keep the skin clean and dry.
Provide meticulous mouth care.
DIAGNOSTIC PROCEDURE Identify factors contributing to fatigue.
Administer iron, folic acid, or vitamin supplements as
Chest X-ray prescribed if anemia occurs.
Echocardiogram
LABORATORIES Monitor the blood urea nitrogen and creatinine levels
Biopsy frequently for signs of renal impairment.
Antinuclear antibody (ANA) test
Provide a high-vitamin and high-iron diet.
Complete blood count Monitor for proteinuria and red cell casts in the urine.
Erythrocyte sedimentation rate Assist with plasmapheresis as prescribed to remove
autoantibodies and immune complexes from the blood
before organ damage occurs.