Mendelian Law of Inheritance

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Mendelian Laws of Inheritance

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3
4
Inheritance

5
How did the experiments of
Gregor Mendel lay the foundation
for the study of transmission
genetics?

6
Introduction to Inheritance

Looking at
yourself in the
mirror...

7
Introduction to Inheritance

8
Introduction to Inheritance

...have you ever


wondered how you
have inherited your
biological traits from
your parents?

9
Introduction to Inheritance

Genetics answers
most of our
inquiries about how
traits are
transmitted from
parents to their
children.

10
Introduction to Inheritance

Genetics

Heredity Variation
11
Introduction to Inheritance

Genetics

Heredity Variation
12
Introduction to Inheritance

Genetics

Heredity Variation
13
Introduction to Inheritance

Genetics

Heredity Variation
14
Introduction to Inheritance

Molecular genetics Cytogenetics

Branches
of
Genetics

Transmission genetics Population genetics


15
Introduction to Inheritance

Molecular genetics Cytogenetics


deals with DNA and
gene expression and
regulation. Branches
of
Genetics

Transmission genetics Population genetics


16
Introduction to Inheritance

Molecular genetics Cytogenetics deals with


chromosome structure and
behavior during cell
Branches division.
of
Genetics

Transmission genetics Population genetics


17
Introduction to Inheritance

Molecular genetics Cytogenetics

Branches
of
Genetics

Transmission genetics
deals with different
patterns of inheritance. Population genetics
18
Introduction to Inheritance

Molecular genetics Cytogenetics

Branches
of
Genetics Population genetics
deals with how
forces of evolution
influence genes in
Transmission genetics populations.
19
Introduction to Inheritance

Transmission genetics, also called classical genetics, is the oldest


subdiscipline of genetics. It attempts to predict outcomes of reproduction.
20
Brief Background of Gregor Mendel

Farm Father of
Tender Genetics

Augustinian
Beekeeper Academicia
Monk
n

21
Brief Background of Gregor Mendel

Mendel took the path to


priesthood when he
entered Augustinian
monastery of St.
Thomas and became
monk. This is also
where he performed
his pea plant studies.

22
Pea Plant Hybridization

Mendel chose
the legumes
garden peas or
Pisum sativum
for his
hybridization
experiments.

23
Pea Plant Hybridization

24
Pea Plant Hybridization

What makes
peas ideal
for genetic
studies?

25
Pea Plant Hybridization

They
What makes exhibit
peas ideal
for genetic vigorous
studies? growth.

26
Pea Plant Hybridization

They can
self-
fertilize.
They
What makes exhibit
peas ideal
for genetic vigorous
studies? growth.

27
Pea Plant Hybridization

They can
self-
fertilize.
They
What makes exhibit They can
peas ideal
for genetic vigorous cross-
studies? growth. fertilize.

28
Challenges faced by Mendel

Pangenesis

Previous Notions Homunculus


of Inheritance theory

Blending
theory
29
Challenges faced by Mendel

Previous
Notions of
Inheritance

Pangenesis

Homunculus
theory

Blending
theory

30
Challenges faced by Mendel

Previous
Notions of
Inheritance

Pangenesis

Homunculus
theory

Blending
theory Pangenesis was the belief that seeds are
produced in different organs and will later
on gather to form the offspring. 31
Challenges faced by Mendel

Previous
Notions of
Inheritance

Pangenesis

Homunculus
theory

Blending
theory The invention of the microscope made
people believe that sperm cells bear a
homunculus or little man. 32
Challenges faced by Mendel

Previous
Notions of
Inheritance

Pangenesis

Homunculus
theory

Blending
theory The blending theory of inheritance
states that traits of parents blend every
generation of offspring. 33
Rediscovery of Mendel’s Work

Hugo de Vries Carl Correns Erich von


(1848–1935) (1864–1933) Tschermak
(1871–1962)
Mendel’s paper, The Experiments on Plant Hybridization, was rediscovered
independently by de Vries, Correns, and von Tschermak in 1900s. 34
What makes Pisum sativum an
ideal model organism for genetic
studies?

35
Review of Genetic Terminologies

A chromosome consists of
a DNA molecule, which serve
as the repository of genetic
information in cells.
Review of Genetic Terminologies

Our chromosomes occur in pairs


called homologous
chromosomes.
Review of Genetic Terminologies

Our chromosomes occur in pairs


called homologous
chromosomes.

Paternal (from the father or male parent)


Review of Genetic Terminologies

Our chromosomes occur in pairs


called homologous
chromosomes.

Paternal (from the father or male parent)

Maternal (from the mother or female parent)


Review of Genetic Terminologies

A gene is the basic unit of


heredity. It controls the expression
of a biological characteristic.
Review of Genetic Terminologies

A gene is the basic unit of


heredity. It controls the expression
of a biological characteristic.

A characteristic is a heritable
feature of an organism.
Review of Genetic Terminologies

In our given example, the gene


controls height of peas.
Review of Genetic Terminologies

Also, note that genes occur in pairs.


Thus, a pair of genes control a
particular characteristic.
Review of Genetic Terminologies

How about this gene pair?


What does it control?
Review of Genetic Terminologies

How about this gene pair?


What does it control?

The highlighted gene


controls seed shape in peas.
Review of Genetic Terminologies

Alleles are
the alternative
forms of a
gene.
Review of Genetic Terminologies

Genotype refers to the set of alleles


possessed by an organism.
Review of Genetic Terminologies

The genotype is
homozygous if
the alleles are
identical.
Review of Genetic Terminologies

The genotype is
heterozygous if
the alleles are
different.
Review of Genetic Terminologies

Let’s say that the given chromosomes give


rise to the following observable traits:

Tall Round-
seeded
Review of Genetic Terminologies

Let’s say that the given chromosomes give


rise to the following observable traits:

Tall Round-
seeded
Phenotypes refer to the actual
manifestation of genotypes into observable
Review of Genetic Terminologies

If the phenotype for seed shape is round, then


we can conclude that:
Review of Genetic Terminologies

If the phenotype for seed shape is round, then


we can conclude that:

The allele for round pea is


the dominant allele.

The allele for wrinkled pea


is the recessive allele.
Pea Plant Characters

Gregor Mendel utilized seven characteristics of peas in his


hybridization experiments. Each exists in two variants. 54
How are tahe alleles of a gene
transmitted from parents to
offspring?

55
Monohybrid Cross

A monohybrid cross is a mating between two individuals


involving one characteristic or one pair of contrasting traits. 56
Monohybrid Cross

In this example, the height of


pea is involved.

57
Monohybrid Cross

In this example, the height of


pea is involved.

The parents have contrasting


traits (i.e., tall and dwarf).

58
Monohybrid Cross

In this example, the height of


pea is involved.

The parents have contrasting


traits (i.e., tall and dwarf).

Both parents must also be


true-breeding or homozygous.

59
Monohybrid Cross

P generation

F1 generation

F2 generation

60
Monohybrid Cross

The parental
P generation generation consists of
the true- breeding initial
parents.

F1 generation

F2 generation

61
Monohybrid Cross

P generation

The first filial


F1 generation generation consists of
the offspring of the P
generation.

F2 generation

62
Monohybrid Cross

P generation

F1 generation

The second filial


F2 generation generation consists of
the offspring of F1 gen.
63
Monohybrid Cross

Result 1:
The dwarf trait
disappeared in the F1
generation.

64
Monohybrid Cross

P
generation
Result 1:
The dwarf trait
disappeared in the F1
generation.

F1
generation

65
Monohybrid Cross

P
generation
Result 1:
The dwarf trait
disappeared in the F1
generation.

F1
Explanation: generation
Tall trait must be
dominant over the
dwarf trait.

66
Monohybrid Cross

Principle of
Dominance

In a heterozygous individual, one allele


(dominant) completely masks the
expression of the other allele
(recessive).
67
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

68
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

T - tall

69
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

T - tall
t - dwarf

70
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

T - tall
t - dwarf
Thus, we will have the corresponding genotypes and
phenotypes :

71
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

T - tall
t - dwarf
Thus, we will have the corresponding genotypes and
phenotypes :
TT - tall
72
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

T - tall
t - dwarf
Thus, we will have the corresponding genotypes and
phenotypes :
TT - tall Tt - tall
73
Monohybrid Cross

Principle of
Dominance
If we assign letters to each allele :

T - tall
t - dwarf
Thus, we will have the corresponding genotypes and
phenotypes :
TT - tall Tt - tall tt - dwarf
74
Monohybrid Cross

Thus, we can have the genetic cross as follows:

75
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation

F1 generation

F2 generation
76
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf

F1 generation

F2 generation
77
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf TT × tt

F1 generation

F2 generation
78
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf TT × tt


Phenotypic Ratio Genotypic Ratio (GR):
(PR):
F1 generation

F2 generation
79
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf TT × tt


Phenotypic Ratio Genotypic Ratio (GR):
(PR):
F1 generation 100% or All Tall

F2 generation
80
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf TT × tt


Phenotypic Ratio Genotypic Ratio (GR):
(PR):
F1 generation 100% or All Tall 100% or All Tt

F2 generation
81
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf TT × tt


Phenotypic Ratio Genotypic Ratio (GR):
(PR):
F1 generation 100% or All Tall 100% or All Tt

F2 generation 3/4 Tall: 1/4 Dwarf


82
Monohybrid Cross

Thus, we can have the genetic cross as follows:

Phenotypes Genotypes

P generation Tall × Dwarf TT × tt


Phenotypic Ratio Genotypic Ratio (GR):
(PR):
F1 generation 100% or All Tall 100% or All Tt

F2 generation 3/4 Tall: 1/4 Dwarf 1/4 TT: 2/4 Tt: 1/4 tt
83
Monohybrid Cross

Result 2:
The phenotypes in
the F2 generation
occur in a ratio of 3:1.

84
Monohybrid Cross

F1
generation
Result 2:
The phenotypes in
the F2 generation
occur in a ratio of 3:1.

F2
generation

85
Monohybrid Cross

F1
generation
Result 2:
The phenotypes in
the F2 generation
occur in a ratio of 3:1.

F2
generation

86
Monohybrid Cross

F1
generation
Result 2:
The phenotypes in
the F2 generation
occur in a ratio of 3:1.

F2
Explanation: generation
The alleles are
segregating during
gamete formation.

87
Monohybrid Cross

Law of
Segregation

The two alleles of a gene in an individual


segregate or separate from each other
during gamete formation.

88
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

89
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

90
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles

91
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t

92
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t

progeny

93
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t

progeny Tt Tt

94
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t

progeny Tt Tt Tt Tt

95
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t

progeny Tt Tt Tt Tt

96
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t T t T t

progeny Tt Tt Tt Tt

97
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t T t T t

progeny Tt Tt Tt Tt TT Tt

98
Monohybrid Cross

Law of Segregation
P generation cross F1 generation cross

TT × tt Tt × Tt

alleles T T t t T t T t

progeny Tt Tt Tt Tt TT Tt Tt tt

99
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
2. Write the genotypes. gen cross.
3. Identify the alleles.

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 100
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
3. Identify the alleles.

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 101
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the alleles.

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 102
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the alleles. T T t t

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 103
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the alleles. T T t t

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 104
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the gametes. T T t t

4. Draw the square.


T T
5. Distribute gametes.

6. Combine gametes. t
7. Determine
phenotypes. t
8. Determine ratios. 105
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the alleles. T T t t

4. Draw the square.


T T
5. Distribute alleles.

6. Combine alleles. t Tt Tt

7. Determine
phenotypes. t Tt Tt
8. Determine ratios. 106
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the alleles. T T t t

4. Draw the square.


T T
5. Distribute alleles.

6. Combine alleles. t Tt Tt
(Tall) (Tall)
7. Determine
phenotypes. t Tt Tt
8. Determine ratios. (Tall) (Tall) 107
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
Tall × Dwarf
2. Write the genotypes. gen cross.
TT × tt

3. Identify the alleles. T T t t

4. Draw the square.


T T
5. Distribute alleles.

6. Combine alleles. t Tt Tt
(Tall) (Tall) GR: 100% Tt
7. Determine PR: 100% Tall
phenotypes. t Tt Tt
8. Determine ratios. (Tall) (Tall) 108
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
2. Write the genotypes. gen cross.
3. Identify the alleles.

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 109
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
3. Identify the alleles.

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 110
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles.

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 111
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles. T t T t

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 112
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles. T t T t

4. Draw the square.

5. Distribute alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 113
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles. T t T t

4. Draw the square.


T t
5. Distribute alleles.

6. Combine alleles. T
7. Determine
phenotypes. t
8. Determine ratios. 114
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles. T t T t

4. Draw the square.


T t
5. Distribute alleles.

6. Combine alleles. T TT Tt

7. Determine
phenotypes. t Tt tt
8. Determine ratios. 115
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles. T t T t

4. Draw the square.


T t
5. Distribute alleles.

6. Combine alleles. T TT Tt
(Tall) (Tall)
7. Determine
phenotypes. t Tt tt
8. Determine ratios. (Tall) (Dwarf) 116
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
Tall × Tall
2. Write the genotypes. gen cross.
Tt × Tt

3. Identify the alleles. T t T t

4. Draw the square.


T t
5. Distribute alleles.
GR:
6. Combine alleles. T TT Tt 1/4 TT: 2/4 Tt: 1/4 tt
(Tall) (Tall)
7. Determine PR:
phenotypes. t Tt tt 3/4 Tall: 1/4 Dwarf
8. Determine ratios. (Tall) (Dwarf) 117
Dihybrid Cross

A dihybrid cross is a mating between two individuals


involving two characteristics or two pairs of contrasting 118
Dihybrid Cross

119
Dihybrid Cross

In this example, the seed shape


and seed color are involved.

120
Dihybrid Cross

In this example, the seed shape


and seed color are involved.

Two pairs of contrasting traits are


involved: round/wrinkled and
yellow/green.

121
Dihybrid Cross

In this example, the seed shape


and seed color are involved.

Two pairs of contrasting traits are


involved: round/wrinkled and
yellow/green.

Both parents must also be true-


breeding or homozygous.

122
Dihybrid Cross

In this example, the seed shape


and seed color are involved.

Two pairs of contrasting traits are


involved: round/wrinkled and
yellow/green.

Both parents must also be true-


breeding or homozygous.

All of the offspring in F1 have round


and yellow seeds due to
dominance. 123
Punnett Square

1. Write the given. Let’s apply Punnett


square to our P
2. Assign alleles. gen cross.
3. Write genotypes.

4. Identify the alleles.

5. Draw the square.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 124
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes.

4. Identify the alleles.

5. Draw the square.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 125
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes.

4. Identify the alleles.

5. Draw the square.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 126
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes. Seed shape:

4. Identify the alleles. Round seed is dominant over wrinkled seed.

5. Draw the square.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 127
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes. Seed shape:

4. Identify the alleles. Round seed is dominant over wrinkled seed.

5. Draw the square. R - round r - wrinkled

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios. 128
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes. Seed shape:

4. Identify the alleles. Round seed is dominant over wrinkled seed.

5. Draw the square. R - round r - wrinkled

6. Combine alleles. Seed color:

7. Determine Yellow seed is dominant over green seed.


phenotypes.
8. Determine ratios. 129
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes. Seed shape:

4. Identify the alleles. Round seed is dominant over wrinkled seed.

5. Draw the square. R - round r - wrinkled

6. Combine alleles. Seed color:

7. Determine Yellow seed is dominant over green seed.


phenotypes.
8. Determine ratios. Y - y - green
130
yellow
Punnett Square

1. Write the given. Let’s apply Punnett Round, Wrinkled


square to our P yellow
× , green
2. Assign alleles. gen cross.
3. Write genotypes. Seed shape:

4. Identify the alleles. Round seed is dominant over wrinkled seed.

5. Draw the square. R - round r - wrinkled

6. Combine alleles. Seed color:

7. Determine Yellow seed is dominant over green seed.


phenotypes.
8. Determine ratios. Y - y - green
131
yellow
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Wrinkled


square to our P yellow , green
2. Assign alleles. gen cross.
RRYY × rryy
3. Write genotypes.

4. Identify the alleles.

5. Draw the square.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Wrinkled


square to our P yellow , green
2. Assign alleles. gen cross.
RRYY × rryy
3. Write genotypes. R r
Y y
4. Identify the alleles.

5. Draw the square.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Wrinkled


square to our P yellow , green
2. Assign alleles. gen cross.
RRYY × rryy
3. Write genotypes. R r
Y y
4. Identify the gametes.
R R
5. Draw the square. Y Y
r
6. Combine alleles.
y
7. Determine
phenotypes. r
8. Determine ratios. y
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Wrinkled


square to our P yellow , green
2. Assign alleles. gen cross.
RRYY × rryy
3. Write genotypes. R r
Y y
4. Identify the alleles.
R R
5. Draw the square. Y Y
r RrYy RrYy
6. Combine alleles.
y
7. Determine
r RrYy RrYy
phenotypes.
8. Determine ratios. y
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Wrinkled


square to our P yellow , green
2. Assign alleles. gen cross.
RRYY × rryy
3. Write genotypes. R r
Y y
4. Identify the alleles.
R R
5. Draw the square. Y Y
r RrYy RrYy
6. Combine alleles.
y (round, (round,
7. Determine yellow) yellow)
phenotypes. r
y RrYy RrYy
8. Determine ratios.
(round, (round,
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Wrinkled


square to our P yellow , green
2. Assign alleles. gen cross.
RRYY × rryy
3. Write genotypes. R r
Y y
4. Identify the alleles.
R R
5. Draw the square. Y Y
r RrYy RrYy GR:
6. Combine alleles. 100% RrYy
y (round, (round,
7. Determine yellow) yellow) PR:
phenotypes. r 100% round,
y RrYy RrYy
8. Determine ratios. yellow
(round, (round,
Punnett Square

1. Write the given. Let’s apply Punnett


square to our F1
2. Write genotypes. gen cross.
3. Identify the alleles.

4. Draw the square.

5. Distribute the alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
3. Identify the alleles.

4. Draw the square.

5. Distribute the alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.

4. Draw the square.

5. Distribute the alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.
TIP: Use the branching technique.
4. Draw the square.

5. Distribute the alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.
TIP: Use the branching technique.
4. Draw the square. Rr Yy
5. Distribute the alleles.
R
6. Combine alleles.

7. Determine
phenotypes. r
8. Determine ratios.
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.
TIP: Use the branching technique.
4. Draw the square. Rr Yy
5. Distribute the alleles. Y
R
6. Combine alleles. y
7. Determine Y
phenotypes. r
8. Determine ratios. y
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.
TIP: Use the branching technique.
4. Draw the square. Rr Yy
5. Distribute the alleles. Y
R
6. Combine alleles. y
7. Determine Y
phenotypes. r
8. Determine ratios. y
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.
TIP: Use the branching technique.
4. Draw the square. Rr Yy
R
5. Distribute the alleles. Y Y
R R
6. Combine alleles. y y
r
7. Determine Y Y
phenotypes. r
8. Determine ratios. r
y y
Punnett Square

1. Write the given. Let’s apply Punnett Round, × Round,


square to our F1 yellow yellow
2. Write genotypes. gen cross.
RrYy × RrYy
3. Identify the alleles.
TIP: Use the branching technique.
4. Draw the square. Rr Yy
R
5. Distribute the alleles. Y Y Thus, the
R R genotype
6. Combine alleles. y y RrYy has
r four possible
7. Determine Y Y
phenotypes. gametes.
r r
8. Determine ratios. y y
Punnett Square

1. Write the given. RrYy × RrYy


2. Write genotypes.

3. Identify the alleles.

4. Draw the square.

5. Distribute the alleles.

6. Combine alleles.

7. Determine
phenotypes.
8. Determine ratios.
Punnett Square

1. Write the given. RrYy × RrYy


R R r r
2. Write genotypes. Y y Y y
R
3. Identify the alleles. Y
4. Draw the square. R
y
5. Distribute the alleles.
r
6. Combine alleles. Y

7. Determine r
phenotypes. y
8. Determine ratios.
Punnett Square

1. Write the given. RrYy × RrYy


R R r r
2. Write genotypes. Y y Y y
R RRYY RRYy RrYY RrYy
3. Identify the alleles. Y
4. Draw the square. R RRYy RRyy RrYy Rryy
y
5. Distribute the alleles.
r RrYY RrYy rrYY rrYy
6. Combine alleles. Y

7. Determine r RrYy Rryy rrYy rryy


phenotypes. y
8. Determine ratios.
Punnett Square

1. Write the given. RrYy × RrYy


R R r r
2. Write genotypes. Y y Y y
R RRYY RRYy RrYY RrYy
3. Identify the alleles. Y round, round, round, round,
yellow yellow yellow yellow
4. Draw the square. R RRYy RRyy RrYy Rryy
round, round, round, round,
y
5. Distribute the alleles. yellow green yellow green

r RrYY RrYy rrYY rrYy


6. Combine alleles. round, round, wrinkled wrinkled
Y yellow yellow yellow yellow
7. Determine r RrYy Rryy rrYy rryy
phenotypes. round, round, wrinkled wrinkled,
y
yellow green yellow green
8. Determine ratios.
Punnett Square

1. Write the given. RrYy × RrYy


R R r r
2. Write genotypes. Y y Y y
R RRYY RRYy RrYY RrYy
3. Identify the alleles. Y round, round, round, round,
yellow yellow yellow yellow
4. Draw the square. R RRYy RRyy RrYy Rryy
round, round, round, round,
y
5. Distribute the alleles. yellow green yellow green

r RrYY RrYy rrYY rrYy


6. Combine alleles. round, round, wrinkled wrinkled
Y yellow yellow yellow yellow
7. Determine r RrYy Rryy rrYy rryy
phenotypes. round, round, wrinkled wrinkled,
y
yellow green yellow green
8. Determine ratios.
Punnett Square

1. Write the given. RrYy × RrYy


2. Write genotypes. Genotypic Ratio:
3. Identify the alleles. 1/16 RRYY 2/16 RrYY 1/16 rrYY
4. Draw the square. 2/16 RRYy 4/16 RrYy 2/16 rrYy
1/16 RRyy 2/16 Rryy 1/16 rryy
5. Distribute the alleles.
Phenotypic
6. Combine alleles.
Ratio:
7. Determine 9/16 round, 3/16 wrinkled, yellow
phenotypes. yellow
8. Determine ratios.
3/16 round, green 1/16 wrinkled, green
Dihybrid Cross

Result 2:
The phenotypes in the F2
generation occur in a ratio
of 9:3:3:1

153
Dihybrid Cross

Result 2:
The phenotypes in the F2
generation occur in a ratio
of 9:3:3:1

154
Dihybrid Cross

Result 2:
The phenotypes in the F2
generation occur in a ratio
of 9:3:3:1

Explanation:
The genes for seed shape
and color are
independently assorting.

155
Dihybrid Cross

Law of Independent
Assortment
The alleles from different genes are
sorted into the gametes independently of
each other. Thus, the inheritance of
these two genes become independent.
156
Is the law of segregation still
applicable when two genes are
already involved? Why do you
think so?

157
Laws of Inheritance and Gametogenesis

Both laws of
inheritance operate
during the
Anaphase I of
meiosis during
gamete formation.

158
How is the separation of
homologous chromosomes
relevant to the laws of
inheritance?

159
Brylle is fond of growing crops in his garden. One of the
crops that he cultivates is the garden pea (Pisum sativum).
One strain of his pea plants is heterozygous for flower
colors, with genotype Mm. Another strain of his peas has
smooth pods and axial flowers with genotype AaBB. What
are the alleles produced by each of these two plants with
respect to the indicated characteristics?

160
Brylle is fond of growing crops in his garden. One of the
crops that he cultivates is the garden pea (Pisum sativum).
One strain of his pea plants is heterozygous for flower
colors, with genotype Mm. Another strain of his peas has
smooth pods and axial flowers with genotype AaBB. What
are the alleles produced by each of these two plants with
respect to the indicated characteristics?

Plant 1 (Mm) produces gametes with alleles M and m, while


Plant 2 (AaBB) produces gametes with allele combinations AB
and aB.
161
Nickson cultivated two different plants.
The first plant is recessive for trait A,
while the second plant is homozygous
dominant for trait B and heterozygous for
trait C. What are the allele combinations
that can be produced by his first and
second plants?

162
In pea plants, axial inflorescence is dominant over terminal
inflorescence. If Laiza crossed a parent plant that is
heterozygous for inflorescence to another plant with
terminal inflorescence, what are the genotypic and
phenotypic ratios of the offspring?

163
In pea plants, axial inflorescence is dominant over terminal
inflorescence. If Laiza crossed a parent plant that is
heterozygous for inflorescence to another plant with
terminal inflorescence, what are the genotypic and
phenotypic ratios of the offspring?

The genotypic ratio of the cross is 1/2 AA: 1/2 aa. The
phenotypic ratio is 1/2 axial: 1/2 terminal.
164
If a parent pea plant that is hybrid for
flower color is crossed with a plant that is
true-breeding for violet flowers, what are
the genotypic and phenotypic ratios of the
F1 generation? Note that having violet
flowers is dominant over having white
flowers.

165
In pea plants, round seeds are dominant over wrinkled
seeds, while the tall trait is dominant over the dwarf trait. If
you cross two plants that are both heterozygous for seed
shape but homozygous dominant for height, what are the
expected genotypic and phenotypic ratios of the offspring?

166
In pea plants, round seeds are dominant over wrinkled
seeds, while the tall trait is dominant over the dwarf trait. If
you cross two plants that are both heterozygous for seed
shape but homozygous dominant for height, what are the
expected genotypic and phenotypic ratios of the offspring?

The genotypic ratio of the offspring of the cross is 1/4 AABB:


2/4 AaBB: 1/4 aaBB. The phenotypic ratio is 3/4 round tall: 1/4
wrinkled tall.
167
Gene A codes for seed color, where
having yellow seed is dominant over
having a green seed. Gene B codes for
pod shape, where the smooth pod is
dominant over the constricted pod. Given
the cross AaBB × AABb, what is the
genotypic and phenotypic ratio of the
offspring?
168
Determine the accuracy of each of the following
statements. Write true if the statement is correct and
false if otherwise.
1. If the genes for seed shape and height of peas are
independently assorting, then they highly influence the
inheritance of each other.
2. The F2 generation is the offspring of the P generation.
3. Both the laws of inheritance operate during the first
anaphase of meiosis.
169
Provide what is asked in each of the following items.

1. What are the alleles produced by an individual with


genotype NN?
2. What are the alleles produced by an individual with
genotype Bb?
3. What are the alleles produced by an individual with
genotype Mmnn?

170
● Genetics is the study of inheritance and variation in
organisms. It has various subdisciplines.
Transmission genetics is the one that is
particularly concerned about the mechanisms or
patterns of inheritance.

171
● Gregor Mendel is the father of genetics. He
performed experiments on garden pea or Pisum
sativum. This led him to formulate the laws of
inheritance in his publication, Experiments on Plant
Hybrids.

172
● Different genes control the expression of the
characteristics of organisms. Each gene exists in
alternative forms called alleles.

● In terms of expression, genes can either be dominant


or recessive. According to the principle of
dominance of Mendel, in a heterozygous individual,
the dominant allele tends to mask the expression of
the recessive allele. 173
● Mendel’s monohybrid cross reveals the law of
segregation. According to this law, the alleles
segregate during gametogenesis. This explains the
characteristic 3:1 phenotypic ratio of F2 in
monohybrid crosses.

174
● Mendel’s dihybrid cross reveals the law of
independent assortment. According to this law,
allele pairs from different genes separate
independently during gamete formation. This
explains the characteristics ratio of 9:3:3:1 of F2 of
dihybrid crosses.

175
Transmission genetics serves as the pioneer field in genetics.

176
You crossed two true-breeding lines of
violet-flowered and white-flowered
peas. Is it possible to establish a true-
breeding line of the genotype found in
the offspring of your cross? Why or
why not?

177

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