Consider the S.

E time independent
2
∂ −ℏ 2
iℏ ψ= ∇ ψ +V ( r ) ψ
∂t 2m
We assume the ψ to be separable s.t.

ψ ( r ,t )=Ψ ( r ) ϕ (t )
Then
2
∂ −ℏ 2
iℏ ψ= ∇ ψ +V ( r ) ψ
∂t 2m
2
∂ ( ) −ℏ 2 ( )
iℏ Ψ r ϕ (t)= ∇ Ψ r ϕ (t)+V ( r ) Ψ ( r ) ϕ(t )
∂t 2m

[ ]
2
∂ ( ) ( ) −ℏ 1 ∂ 2 ∂
iℏ Ψ r ϕt= r ( Ψ ( r ) ϕ (t)) + V ( r ) Ψ ( r ) ϕ (t )
∂t 2m r 2 ∂ r ∂ r

[ [
−ℏ ϕ ( t ) ∂ 2 ∂
[ ]] ]
2
∂ 1
iℏ Ψ ( r ) ϕ ( t )= r +V ( r ) Ψ ( r ) ϕ ( t )
∂t 2
2m r ∂r ∂r ϕ ( t ) Ψ (r)

We separate the variables

[ ]
∂
ϕ (t)
[ ]
2
∂t −ℏ 1 ∂ 2
iℏ = r ( Ψ ( r ) ) +V ( r )
ϕ (t) 2
2 m r Ψ (r ) ∂ r

Since they are totally dependent on each other, we can equate each side to a constant.

∂
ϕ(t )
∂t
iℏ =E
ϕ (t )

[ ]
2
−ℏ 1 ∂ 2 ( )
2
r ( Ψ r ) +V ( r )=E
2 m r Ψ (r ) ∂ r

From this we can obtain an expression for V (r )

[ ]
2
−ℏ 1 ∂ 2 ( )
2
r ( Ψ r ) +V (r)=E
2 m r Ψ (r ) ∂ r
 [ ]
2
ℏ 1 ∂ 2 ( )
V ( r )=E+ r (Ψ r )
2 m r2 Ψ ( r ) ∂ r