Professional Documents
Culture Documents
Block e nwsm-1
Block e nwsm-1
Marks
What is the name of the structure present at the angles of a classic A Acinus
1
liver lobule? B Portal triad [T]
C Central vein
D Hepatocyte
E Sinusoids
What is the space called that is located at the portal area between A Space of Disse
1
the hepatocytes and connective tissue? B Space of Mall [T]
C Vacuole
D Lacuna
E Howship’s lacuna
C Jejunum
D Ilium
Embryologically the three parts of the gut tube receive their blood A Inferior mesenteric artey
supply from different arteries. The arterial supply of jeunum is 1 B Superior mesenteric artery [T]
from
C Gastroduedenal artery
D Celiac trunk
E Splenic artery
Embryologically the three parts of the gut tube receive their blood A Superior Mesenteric artery
supply from different arteries. The rectum receives its blood 1 B Superior vesical artery
supply from which of the following arteies?
C Lateral sacral artery
C Jejunum
D Ileum [T]
E Cecum
A 40 years old male patient has a penetrating ulcer on the A Common hepatic artery
posterior wall of first part of duodenum. Which of the following 1 B Hepatic artery proper
blood vessel is most likely subject to erosion:
C Celiac artery
B Right kidney
D Gastroduodenal artery
E Descending colon
Which of the following vessels are the contents of the greater A Right & left gastric vessels
1
omentum of the stomach? B Right & left gastro-epiploic vessels [T]
C Portal vein
E Splenic artery
In which part of the oesophagus does the muscularis externa A Upper third
1
contain both smooth & skeletal muscles B Upper fourth
D Lower third
E Lower fourth
E Spleen
A 52 years old man comes to the emergency department for A Coeliac nodes [T]
severe upper abdominal pain. Endoscopy reveals a tumour in B Hepatic nodes
antrum of stomach. A CT scan was done to find the extent of 1
spread of the tumour. Which of the following lymph nodes can be C Inferior mesenteric nodes
involved? D Lumbar nodes
Celiac trunk is ligated by the surgeon, which structure would not A Stomach
0
be suffering from ischemia: B Liver
C Spleen
D Gall bladder
E Pancreas [T]
C L3
D L4
E L5
The systemic veins at the lower end of esophagus are drained into A Hemiazygous vein [T]
0
which of the following veins? B IVC
C Lt Renal vein
D Rt Renal vein
E Thoraco-epigastric veins
Which of the following is derived from the foregut endoderm ? 1 A Beta cells of pncrease [T]
D Kuffer cells
E portal vein
One of the contents of meso appendix is “appendicular artery”. A Right colic branch of superior mesenteric artery
This appendicular artery is a branch of which of the following 1 B Middle colic branch of superior mesenteric artery
arteries?
C Ilio colic branch of superior mesenteric artery [T]
C L2 [T]
D L3
E L4
Which one of the following structures is crossed by the root of A Left ureter
1
mesentery attached on the posterior abdominal wall B Left Psoas major muscle
C Linea alba
D Rectus sheath
E Conjoint tendon
C Paraxial mesoderm
D Intermediate mesoderm
E Endoderm [T]
The smooth muscles and C.T in the wall of Esophagus is derived A Somatic mesoderm
1
from which of the following Germ layers B Splanchnic mesoderm [T]
C Paraxial mesoderm
D Intermediate mesoderm
E Endoderm
During SGD session,the facilitator asked the students that A Primitive pharynx
1
Esophagus is developed from which of the following structures B Respiratory diverticulum
The Professor of anatomy mentioned in his LCF that there are four A 6”from incisor teeth [T]
normal compression/ indentations in the entire length of B 9”from incisor teeth
esophagus which are considered during endoscopy procedure. He 1
C 11”from incisor teeth
asked that the 1st compression lies at which level with reference
to incisor teeth D 12”from incisor teeth
The arterial supply of abdominal part of esophagus is from which A Rt. Gastric A
0
artery: B Left Gastric A [T]
C Splenic A
D Rt. gastro-epiploic A
E Lt gastro-epiploic A
D C6 vertebra [T]
E T2 vertebra
A 20m year old male received a harsh blow to his abdomen in the A descending colon
upper left quadrant during a fist fight and was taken to the hospital B left kidney
emergency room. Examination showed low blood pressure and
C pancreas
tenderness on the left mid-axillary line. Also a large swelling was
1
felt protruding downwards and medially below the left costal D spleen [T]
margin. X-ray revealed that the 9th and 10th ribs were fractured
E stomach
near their angles on the left side. The abdominal organ most likely
to be injured due to the fracture is:
Which one of the following options is the Posterior relation of the A diaphragm
0
right kidney: B diaphragmatic recesses
D psoas muscle
E subcostal nerve
After arising from the uretero-pelvic junction, the ureters descend A Quadrates lumborum
through the abdomen on the anterior surface of which of the 1 B psoas minor
following muscle?
C psoas major [T]
D iliacus
E transversus abdominis
C pancreas
D duodenum [T]
E jejunum
E Extends from L1 to L5
The left renal vein receives tributaries from several organs before A pancreas
terminating in the Inferior Vena Cava. Which of the following 1 B right ovary
structure is drained by the Left renal vein ?
C left ovary [T]
D bladder
E left ureter
D Seminal vesicles
E Thyroid gland
C Seminal vesicles
D Testes
E Thyroid
Regarding the structural differences between the male and female A Stratified squamous epithelium
urethrae, which of the following structures is present in the male 0 B Transitional epithelium [T]
urethra but is not present in the female urethra?
C Glands of Littre
E Lumbar arteries
Prostate gland has different lobes in relation to prostatic urethra. A Anterior lobe
Which one of its lobes is located between prostatic urethra and 1 B Posterior lobe
ejaculatory duct?
C Median lobe [T]
C 8 gram [T]
D 10 gram
E 12 gram
The trigone on the posterior wall of the urinary bladder is formed A incorporation of the lower ends of the mesonephric ducts [T]
1
by the : B incorporation of of the lower ends of the pronephric ducts
C epispadius [T]
D hypospadias
E Urachal fistula
E sphincter urethra
C Gastrin
D Secretin [T]
E Trypsinogen
E Rectosphincteric
Which hormone is released by the presence of fat and protein in A Cholecystokinin [T]
the small intestine and has a major effect in decreasing gastric 1 B Glucose dependant insulinotropic peptide
emptying?
C Gastrin
D Motilin
E Secretin
Which of the following best describes the mechanism for fructose A Endocytosis
0
movement across the luminal cell membrane of an enterocyte? B Exocytosis
B Larynx
D Soft palate
Motilin is secreted by the stomach and upper duodenum during A Duodenal motility
fasting, and the only known function of this hormone is to B Gastric emptying
increase gastrointestinal motility. Migrating motility complexes
1 C Intestinal bacteria [T]
(MMCs) occur about every 90 minutes between meals and are
thought to be stimulated by motilin. An absence of MMCs causes D Mass movements
an increase in which of the following?
E Swallowing
E Somatostatin
In addition to mucus-secreting cells that line the entire surface of A Body and fundus of stomach
the stomach, the stomach mucosa has two important types of B Fundus of stomach [T]
1
tubular glands—oxyntic glands and pyloric glands. Main gastric
C incisura angularis
glands are present in mucosa of:
D Near lower esophageal sphincter
E Pylorus of stomach
Which of the following is least likely to be a function of Myenteric A increased tonic contraction, or “tone,” of the gut wall [T]
0
plexus? B increased intensity of the rhythmical contractions
which one is least likely regarding spike potential of A Channels responsible are calcium-sodium channels
0
gastrointestinal tract ? B Channels are much slower to open and close than those of nerves
E Occur automatically when the resting membrane more positive than -40mv
A 68 year old woman with hematemesis has heartburn and A Ammonium [T]
stomach pain. Endoscopy shows inflammation involving the B Bile salts
gastric body and antrum as well as a small gastric ulcer. Biopsies
1 C Gastrin
were positive for helicobacter pylori. H.pylori damages the gastric
mucosa primarily by increasing mucosal levels of which D HCl
substance?
E Pepsin
Which statement is most likely regarding Secretin? A It causes gall bladder contraction
1
B It has trophic effect on gastric mucosa
Which of the following is least likelyT regarding cholecystokinin A It causes contraction of gall bladder
0
(CCK)? B It increases gastric emptying [T]
The proenzymc pepsinogen is secreted mainly from which of the A Chief (or peptic) cells of the stomach [T]
1
following cells. B Epithelial cells of the stomach
D P cells of stomach
B Calcium
C Chloride
D Potassium [T]
E Sodium
A 50 years old male visited the Nephrology OPD of Northwest A Bone marrow suppression
Teaching Hospital for complaints of oliguria. On examination B Deficiency of erythropoeitin [T]
periorbital edema and edema feet was noticed. His blood pressure
C Excessive hemolysis
was 180/100 mmHg. Lab investigations were as follows: Hb: 8 1
gm/dl RBC count: 3.5 million/micro liter Urea: 305 mg/dl Serum D Iron deficiency
creatinine: 6.1 mg/dl After analysing all this data what do you think
E Vitamin B12 deficiency
is the most likely cause of his anemia?
Angiotensin converting enzyme (ACE) inhibitors are used for A Decreases the production of Angiotensin I
treatment of some cases of hypertension. Which of the following B Decreases the production of Angiotensin II [T]
1
is the most likely the basic mechanism by which ACE inhibitors
C Decreases the production of Renin
bring blood pressure down?
D Decreases blood volume
Loop Diuretics like furosemide causes diuresis by decreasing A Sodium-amino acid co-transporter
absorption of solutes in the loop of Henle causing osmotic B Sodium-2chloride-potassium co transporter [T]
1
diuresis. Which of the following carrier proteins is most likely
C Sodium-hydrogen cotransporter
inhibited by loop diuretics?
D Sodiumi hydrogen exchanger
E Sodium-glucose cotransporter
Concerning renal function, the g!omerular filtration rate (GFR) is A A fall in the concentration of anti-diuretic hormone in the blood.
1
most likely increased by: B Constriction of the afferent arterioles.
In Proximal convoluted tubule hydrogen ions are secreted into the A Hydrogen ATPase Pump
tubular lumen by secondary active transpot. Which of the 0 B Hydrogen-chloride exchanger
following carrier is most likely responsible for this?
C Hydeogen-potassium antiporter
The Bowman's capsule hydrostatic pressure is one of the A Constriction of Efferent Arteriole
determinants of GFR. The Bowman's Capsule hydrostatic 0 B Increased GFR
pressure is most likely to be increased as a result of:
C Increased Plasma proteins
Antidiuretic hormone (ADH) plays important role in regulation of A Collecting duct [T]
body water. ADH causes reabsorption of water in which segment 1 B Distal convoluted tubule
of nephron?
C Loop of Henle (Thick segment)
The juxtaglomerular complex consists of macula densa cells in the A Increased water reabsorption
initial portion of the distal tubule and juxtaglomerular cells in the B Decreased Sodium reabsorption
walls of the afferent and efferent arterioles. Renin, released by 1
C Angiotensin I formation [T]
juxtaglomerular cells (JG cells) of the juxtaglomerular complex,
mainly causes: D Decreased sodium reabsorption
Nephron is the structural and functional unit of the kidney. Which A Collecting duct
of the following portions of the nephron is impermeable to water 1 B Descending limb of loop of Henle
even in the presence of large amount of ADH?
C Late distal tubule
D Proximal tubule
B 500 ml
C 1000 ml [T]
D 1500 ml
E 2000 ml
Because cell membranes are relatively impermeable to most A ↑se in volume ↓se in osmolarity
solutes but are highly permeable to water, whenever there is a B ↓se in volume ↑se in osmolarity [T]
higher concentration of solute on one side of the cell membrane,
C ↓se in volume ↓se in osmolarity
water diffuses across the membrane toward the region of higher 1
solute concentration.. What happened to the osmolarity and D ↑se in volume ↑se in osmolarity
volume of the intracellular fluid if a hypertonic solution is added to
E No increase in volume and osmolarity
ECF?
Total osmolarity of each of the three compartments is about 282 A 19.3 mm Hg [T]
mOsm/L, with the plasma being about 1 mOsm/L greater than that B 17.3 mm Hg
of the interstitial and intracellular fluids because of the plasma
1 C 15.3 mm Hg
proteins. For this 1 mOsm concentration gradient across the
capillary membrane, how much osmotic pressure is maintained in D 11.3 mm Hg
the capillaries than in the surrounding interstitial spaces?
E 9.3 mm Hg
C Inulin
D PAH [T]
E Sodium
A patient with Chronic renal failure looks pale and complains of A Dietary intake of Iron
fatigue .Blood investigations reveal he is anemic.The Doctor B Erythropoietin [T]
1
started him on Iron tablets but with no response and the
C Folate
symptoms worsened .What should be the next line of treatment ?
D Iron supplements
E Vitamin B12
Glycolysis and HMP shunt have which the following similarity in A ATP is formed
1
both pathways? B Glucose-6-phosphate is an intermediate [T]
D NAD is reduced
E NADP is reduced
The rate limiting enzyme of Ketone body synthesis is which of the A Acetyl-Co A Caboxylase [T]
0
followings? B HMG-Co A Lyase
C HMG-Co A Isomerase
D HMG-Co A Reductase
E HMG-Co A Synthase
C HMG-Co A Isomerase
D MG-Co A Reductase
Which of the following Enzymes are required in both cholesterol & A Acetyl-Co A Caboxylase
1
ketone bodies synthesis ? B HMG-Co A Reductase
C HMG-Co A Isomerase
E HMG-Co A Lyase
C Highly acidic
D low alkaline
E Neutral
A 24-year-old woman presents with diarrhea, dysphagia, jaundice A α-Keto glutarate dehydrogenase complex [T]
and white transverse lines on the fingernails (Mee’s lines). The B Citrate synthase
1
patient is diagnosed with Arsenic poisoning,that inhibits which of
C Isocitrate dehydrogenase
the following enzymes of TCA cycle?
D Malate dehydrogenase
E Succinate dehydrogenase
D 160
E 200 [T]
C alpha-ketoglutrate [T]
D Pyruvate
E Ornithine
Oxidation of which substance in the body yields the most calories A animal protein
1
per gram? B glucose
C glycogen
D lipid [T]
E plant protein
The pentose phosphate pathway is less active in which one of the A adipose tissue
0
following tissues B lactating mammary gland
C liver
D RBCs
D Transaldolase
E Transketolase
A-30 years old lady presented at 8 weeks and 3 days period of A Maternal high levels of Folic acid
gestation with past history of previous two pregnancies affected B Maternal high levels of homocysteine [T]
1
by neural tube defects (NTD). Which of the following can be
C Maternal high levels of homoserine
probable cause?
D Maternal high levels of pyridoxine
55 years old man presents with left sided chest pain. Detail A Increased plasma levels of alanine
examination and laboratory reports show no obvious risk factors B Increased plasma levels of cysteine
like obesity, hypertension, and increased
1 C Increased plasma levels of homocysteine. [T]
cholesterol/triglyceride/Low density lipoprotein (LDL) except right
coronary artery (RCA) stenosis. Which of the following can be the D Low plasma levels of low density lipoproteins.
most likely cause?
E Low plasma levels of triglycerides.
B 2 [T]
C4
D 32
E 38
Diabetic patients usually develop complications like cataract and A Aldose reductase [T]
neuropathy due to high concentration of sorbitol in the tissues. B fructokinse
1
These complication of diabetes mellitus may be prevented by the
blocking which of the following enzymes? C glucogen synthase
D hexokinase
E sorbitol dehydrogenase
E sugarcane juice
A 65 year-old man presents with weight loss and passage of bulky A Celiac disease
stools. Fecal fat test indicates that excretion of fats are 55 g over B crohn"s disease
1
three days (normal is less than 21 g) and it is mostly unsplit fat.
Which of the followings is the most likely cause for this condition: C obstruction of bile duct
A new born vomits after each feeding of milk based formula and A Benign disease with development of cataract
does not gain weight.Biochemical testing reveals severe B Chronic emphysema appearing in early adulthood.
deficiency of galactose-1-phosphate uridyle transferase.If this 0
C Chronic renal failure appearing in adolescence
condition goes untreated,which of the following is the most likely
outcome for this patient: D Gastrointestinal symptoms that remit with puberty
E4
Consider that in a cultured adipocyte cell line you are trying to A 0 CO2,7ATPs,14NADPH [T]
synthesize palmitate(16-C FATTY ACID).During this process how B 8CO2,9ATPs,9NADPH
many net molecules of CO2,adenosine triphosphate(ATP) and 1
C 9CO2,8ATPs,16NADPH
reduced Nicotinamide adenine dinucleotide phosphate(NADPH)
are consumed to make palmitate D 16 CO2,18ATPs,18NADPH
E 18 CO2,18ATPs,18NADPH
Which of the following statements best describes the overall A decrease plasma Ca2+ levels and decrease plasma phosphate levels.
1
biochemical role of PTH? B decrease plasma Ca2+ levels and increase plasma phosphate levels
C increase plasma Ca2+ levels and decrease plasma phosphate levels. [T]
D increase plasma Ca2+ levels and have no effect on plasma phosphate levels
C diacyleglycerol
D inositol triphosphate
E cGMP
E Tetany
C hypophosphatemia
D hypocalcemia [T]
E hypochloremia
D 1,25-di-OH-cholecalciferol [T]
D PROTEINS
A36 year old woman reported with dullpain in the left flank. She A Alkaptonuria
reports fever and inability to pass urine for the last few days. B Cystinuria [T]
Similar history was reported in the last six months. Routine urine
0 C Cystathioninuria
analysis revealed presence of of RBC, puss cells,WBC
casts,aminoacids and characteristic hexagonal crystals.What is D Phenyleketonuria
the probable cause
E Tyrosinuria
A 2 year old boy was brought to Medical Out Patient Department E PFK [T]
for his instability during walking. His brain MRI and PO2 were D PEPCK
0
found to be in normal limits. Where as his serum lactate levels
C PDC (pyruvate dehydrogenase complex)
were high. What could possibly be deficient?
B G6PD
A Fumerase
E Veracity
There are various types of a questionnaire. One such type A Dichotomous Questionnaire
collect qualitative data. They use a basic structure and some B Quasi-structured Questionnaire
branching questions but nothing that limits the responses of a
0 C Structured Questionnaire
respondent. The questions are more open-ended to collect
specific data from participants. Which questionnaire is best D Task-based Questionnaire
defined by the above scenario?
E Unstructured Questionnaire [T]
E Veracity
You are working on a research project with your supervisor to A Case Report
learn about the culture of a specific community and answer the B Cross-Sectional study
research question “What is it like to be a young Afghan Pashtun 1
parent who has at least one Polio afflicted child?” your study C Ethnography [T]
design will be D Grounded Theory
E Phenomenology
You are conducting research to study ideas, beliefs, human A Diagnostic research
behaviors and other research questions that do not involve 1 B Experimental research
studying the relationship between variables, you are conducting a
C Fundamental research
E Quantitative research
B Caecum
In which part of the large bowel do most colorectal cancers occur? 1 A Ascending colon and rectum
B Caecum
Which of the following is not a common cause of peptic ulcer A Chronic alcohol ingestion [T]
1
disease (PUD)? B Nonsteroidal anti-inflammatory drugs (NSAIDs)
An 11 years old present to clinic two weeks after recovery from a A Congestive cardiac failure
skin infection of the lower cheek that was characterized by B Nephrotic Syndrome
multiple small honey crusted lesion. Her mother brought her to
C Nephritic syndrome [T]
clinic because she is worried about the acute onset of malaise, 0
nausea, headache,” puffiness “ around her daughter’s eyes, and D Renal failure
odd “coke-colored” urine. Which of the following finding is
E Urethra obstruction
expected?
D Metoclopramide
E Metronidazole
A laboratory assistant is advised to determine the blood glucose A citrate-phosphate-dextrose with adenine
levels of a diabetic patient. He collected blood into a 5-mL B Heparin
Vacutainer tube. Which of the following preservatives should he 1
use in order to stop glycolysis in blood cells present in tube and C Sodium floride [T]
avoid false negative result for glucose estimation? D Sodium citerate
E 2,3-bisphosphoglycerate
Food-borne diseases are caused by consuming contaminated A Have them not help with cooking food
foods or beverages and they are common among children. What is 1 B When cooking, have them stay out of the kitchen
one of the best ways to help children avoid food-borne diseases?
C Have them wear rubber gloves
D Encourage them to wash their hands before and after having food [T]
All legal means presented in the court of law to prove or disprove A Deposition
1
a matter under investigation is called: B Evidence [T]
C Fact
D Investigation
E Summons
Which one of the following is the outermost Covering of the A fibrous capsule
0
kidney: B perirenal fat
C perirenal fascia
E pararenal fat
C interlobar artery
E segmental artery
B Flank pain
C Hematuria [T]
D Lethargy
E Weight loss
C Obstruction
D Pain
E Vomiting