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Syngene
Syngene
Syngene
To, To,
The Manager, The Manager,
BSE Limited National Stock Exchange of India Limited
Corporate Relationship Department Corporate Communication Department
Dalal Street, Mumbai – 400 001 Bandra (EAST), Mumbai – 400 051
Scrip Code: 539268 Scrip Symbol: SYNGENE
Dear Sir/Madam,
Sub: Investor Presentation under Regulation 30 of SEBI (Listing Obligations and Disclosure
Requirements) Regulations, 2015.
With reference to Regulation 30 of the SEBI (Listing Obligations and Disclosure Requirements)
Regulations, 2015, please find enclosed the Investor Presentation for the quarter and nine months
ended December 31, 2023. The Company will use this presentation for any meeting scheduled with
analysts or institutional investors up to March 31, 2024.
The above-mentioned Investor Presentation will also be available on the website of the Company
www.syngeneintl.com.
Thanking You,
Yours faithfully,
For SYNGENE INTERNATIONAL LIMITED
Digitally signed by PRIYADARSHINI MAHAPATRA
PRIYADARSHIN
DN: c=IN, postalCode=751015, st=ODISHA, street=ODISHA,
l=KHORDA, o=Personal,
serialNumber=df67e39aa5435d22f718c22d0516d97afb1208536f4f
1860285e06c72d0c9992,
I MAHAPATRA
pseudonym=e816ac07281c470d84b50aab1b7bf795,
2.5.4.20=3b3032863a60d6cf503dc962d0b81de07d5cef26229a00b
5f723a1ef57ab0005, email=TOHEY65274@DIXISER.COM,
cn=PRIYADARSHINI MAHAPATRA
Priyadarshini Mahapatra
Company Secretary and Compliance Officer
Certain statements in this release concerning our future growth prospects are forward‐looking statements, which are
subject to a number of risks, uncertainties and assumptions that could cause actual results to differ materially from those
contemplated in such forward‐looking statements.
Important factors that could cause actual results to differ materially from our expectations include, amongst others
general economic and business conditions in India, business outlook of our clientele and their research and development
efforts, our ability to successfully implement our strategy, our growth and expansion plans and technological changes,
changes in the value of the Rupee and other currencies, changes in the Indian and international interest rates, change in
laws and regulations that apply to the Indian and global biotechnology and pharmaceuticals industries, increasing
competition, changes in political conditions in India and changes in the foreign exchange control regulations in India.
Neither the company, nor its directors and any of the affiliates have any obligation to update or otherwise revise any
statements reflecting circumstances arising after this date or to reflect the occurrence of underlying events, even if the
underlying assumptions do not come to fruition.
1 Operating Highlights
3 Syngene strengths
4 Financials
Appendix
• The third quarter was underpinned by positive performance in Development and Total Revenue: Rs 8,828 Mn
Manufacturing Services as well as in the Dedicated Centers. Performance in Revenue from Operations: 9% YoY Reported EBITDA: Rs 2,608 Mn
Discovery Services was impacted by the slowdown in biotech funding Profit After Tax*: Rs 1,145 Mn
• In Manufacturing Services, the Company continued to make good progress on the
long‐term biologics manufacturing partnership with Zoetis. EBITDA from operations margin 27%
Profit after Tax* margin 13%
• Syngene concluded the acquisition of biologics manufacturing facility from Stelis PAT* 4% YoY
Biopharma Ltd. Once operational, the acquisition will add 20,000 litres of biologics
drug substance manufacturing capacity to Syngene’s existing capabilities. It also
includes a commercial scale, high speed, fill‐finish unit, which is an essential 9 Months FY24 Financial Highlights
capability for drug product manufacturing. The facility is expected to be
operational in the second half of FY25, subject to regulatory approvals.
Total Revenue: Rs 26,462 Mn
• In Discovery Services, the Company added an assay biology capability at the Revenue from Operations: 17% YoY
Reported EBITDA: Rs 7,720 Mn
Hyderabad campus to complement the existing Drug Metabolism and Profit After Tax*: Rs 3,299 Mn
Pharmacokinetics (DMPK) and Compound Management facilities
Updated guidance: Revenue growth for the full year around double digits on a constant EBITDA from operations margin 27%
currency basis compared to earlier guidance of mid teens growth PAT* 16% YoY
We offer integrated Sector expertise include Our team includes more Established track record in
solutions across pharmaceuticals, biotech, than ~6,000 scientists out of discovery research and
research, development nutrition, animal health, total ~8,500+ headcount, development for small and
and manufacturing consumer goods and operating across 3 state‐of‐ large molecules. Emerging
specialty chemicals the‐art campuses located in presence in commercial
India’s leading life science manufacturing
hubs: Bangalore, Mangalore
and Hyderabad
All figures are as on March 31, 2023, unless otherwise specified. @ ca. Rs 80 /US$ ^Tangible and Intangible Assets
Flexible Platform with capability across Ring‐fenced infrastructure for exclusive Pre‐clinical to clinical trials Manufacturing of small and large molecules
multiple modalities including small operations for an individual client for commercial supplies
molecule, large molecule, peptides, Drug substance and drug product
oligonucleotides, antibody drug conjugates, Dedicated, multi‐disciplinary team of development cGMP‐compliant facilities
PROTACs scientists
Associated services to demonstrate the State‐of‐the art API manufacturing and
SynVent ‐ our proprietary platform for Access to entire Syngene ecosystem for safety, tolerability and efficacy of the Biologics manufacturing facilities
Integrated Drug Discovery specialist research and development selected drug candidate
operations
SARchitect‐ our proprietary platform for cGMP‐compliant manufacturing of clinical
data visualization and analysis, including supplies, and registration batches for small
features specifically designed to foster molecules
collaboration between scientific experts
across geographies
2
32
6000+ 400+
0.9 250+
2500+ 11
EPS doubled since *FY16 Annual operating cashflow 2.6 x of FY16 3x market capitalization since FY16
5.7
3.1 77
Clinical Supplies
Small Drug Product
Molecules
Biology
Biologics Integrated Drug Substance –
Drug Product HPAPI
Safety Assessment
Specialty Molecules
HPU* (Phase 1)
Integrated Drug
Antibody-Drug Discovery Bio Analytical Lab
(Large Molecules)
Conjugates Commercial Supplies
Oligonucleotides Stability & Analytical
Therapeutic Antibody Services
Discovery & Engineering;
Cell Line Development Bioprocess Development, Process
Characterisation, Clinical Manufacturing
(Microbial & Mammalian)
Computational and Data Sciences:
Bioinformatics, integrative analysis, target dossiers,
systems modeling, cheminformatics and AI
Nurturing young • Syngene Training Academy offers new graduate recruits a six‐month extended induction to help
6000+ scientists delivering talent and them understand the Company’s vision and values while acquiring the skills to be an industrial
high quality solutions – create enhancing science scientist
a competitive edge skills • Science Certification Program is open to all employees to enhance their capabilities keep their
skills up to date and provide opportunities for continuous learning
• The Company has strong equal opportunity policies to protect against all forms of
Promoting discrimination and provide a workplace where all employees can deliver their best work
workplace diversity • Support provided to parents of young families. 28% of our workforce are female and 20% of
senior management positions are held by females
71%
Dedicated R&D Labs Full time equivalent (FTE) Fee For service (FFS) Risk‐reward
• Dedicated scientific resources
• Dedicated scientific and support • Flexible, on‐demand resources with • Rewards based on clearly defined,
selected from partner‐specified
personnel customized and managed to targeted skill sets pre‐agreed milestones
disciplines
partner requirements • Clearly defined project, limited in • Project scope spans drug
• Deliverables and team composition
• Dedicated infrastructure implemented scope and deliverables discovery, product development or
evolve as project advances
and maintained by Syngene based • Effective way to managed fluctuating truly end to end across both
upon partner specifications • Typically ~3 year contract term
demand, ad‐hoc requests or uncertain
ensures team continuity,
• Access to additional R&D, quantity of work
adjustable with specified notice
Manufacturing and support functions
period
at Syngene
• Effective for longer‐term research
• Long‐term (5‐7 years) contractual
commitments
commitment
… and are open to any single or combination of above
Continuous improvement
embedded in operations driven by Focused execution through strong Project
certified operational leaders Management
Six Sigma Black Belt certified staff in each Structured program management for executing client
service line and support function projects enabled by SynPro platform and SynPro
Green belt certified staff across operations Academy ensuring delivery of client projects
All employees white belt certified
At Syngene, we have adopted Lab 4.0, deploying technology for compliance, Certification as per ISO 13485:2016, ISO/IEC
as an optimizer and as an augmenter 27001 and ISO 9001:2015 requirements
Committed to environmental
protection
• Committed to Science‐based
targets for greenhouse gases
Safety is our first priority • 90+% of total hazardous and
• Accredited with ISO 45001:2018 non‐hazardous waste recycled
for Occupational Health and • 75% of energy procured from
Safety (OH&S) measures green energy sources
• Risk assessments are an integral • 3.8% YoY reduction in energy
part of our operation: a usage
proactive approach in incident • 2683 MT equivalent CO2 savings
prevention from energy conservation
• Kavach, our flagship safety • 52834 MT equivalent CO2
program, has delivered savings from green power.
improvement in safety metrics • 40% YoY freshwater savings
and drives focus on industrial achieved
safety for all employees • 71389 KL fresh water saved from
• Lost time injury frequency rate recycling, reusing and rainwater
(LTIFR ): 0.08 harvesting.
• 69,280 hours of EHSS training • 1021 KL water rainwater
harvested
Refer to the CSR link on our website to know about our corporate social responsibility pursuits on healthcare, education, environment, rural development
Refer to the ESG Report on our website to know more
All figures are as on March 31, 2023, unless otherwise specified Putting Science to Work 23
International accreditations
• USFDA,OHSAS 18001
• GLP, cGMP, AAALAC & CPCSEA Certified facilities
• CAP accreditation, ISO/IEC 27001:2013 accreditation
• EMA and PMDA approved, AAALAC accredited facility
• The safety assessment laboratories and large molecule bioanalytical lab are ISO IEC 17025:2017 certified by the National
Accreditation Board for Testing and Calibration Laboratories (NABL)
• Dream Companies to Work Award at the 29th Edition of the World HRD Congress • Golden Peacock Award 2023: For risk
• Ranked as one of the 25 fastest growing companies in India by Awards. management practices under the Pharmaceutical
Outlook Business • Asian Leadership Award for Excellence in Branding and Marketing in the Contract sector category.
• CMO Leadership Awards 2019 ‐ Presented by Life Science Leader Research Development and Manufacturing category • Awarded India Best Managed Company by Deloitte
Magazine • CRISIL awards Syngene Top score among Indian Pharma ‐ for Environment Safety • Kaizen Excellence Awards:, Won four gold awards
• FICCI CSR Award for Environmental Sustainability ‐ At the 17th Governance (ESG) at QCFI under different categories
Edition of the awards in New Delhi • Syngene ranked #69 in Fortune India magazine's list of 'Top 100 Indian wealth creators • Supply Chain Champion Award, 2023 : Winner in
• Safe Workplace Champion Award ‐ At the 8th Manufacturing 2021’ the ISCM Supply Chain Ranking in the
Supply Chain Summit and Awards • India Pharma Awards 2021 for Operational Excellence–Manufacturing organized by pharmaceutical sector
• Best Leadership Development Program for Middle Management Informa Markets, India • Best Overall Sustainable Performance
Award ‐ At the 6th Global Training and Development Leadership • Best Governed Company in the Listed Segment: Medium Category at the 21st National (Pharmaceutical) 2023 at the 2nd Edition India
Awards Awards for Excellence in Corporate Governance by The Institute of Company Secretaries Sustainability Conclave & Awards 2023
• India Pharma Award 2019 ‐ For “Excellence in Contract Research of India (ICSI) • Excelled at CII National Six Sigma
and Manufacturing Services” at CPhI & P‐MEC India Expo. • Most Innovative New Learning Programme at the L&D Vision & Innovation Award Competition winning 4 Platinum awards.
• Utthama Suraksha Puraskar 2019 ‐ (Pharma and Chemical organized by Transformance Forums
Manufacturing Category) by National Safety Council of India • Mahatma Award 2021 under Health & Wellbeing Category
(NSCI). Leadership Awards • Best Corporate Foundation Award at the World CSR Congress
Putting Science to Work 25
Robust risk management framework
Syngene has a risk management framework to identify, monitor, report and manage risk
Every risk owner monitors and manages risks relevant to their area of responsibility
Refer Annual report for complete risk profile and risk mitigation strategy
Other expenses 1,063 876 21% 1,022 4% Net Fixed assets 37,152
Foreign exchange (gain)/loss, net 124 156 ‐21% 179 ‐31% Other net assets (1) ‐842
EBITDA 2,608 2,482 5% 2,757 ‐5%
Net cash/(debt) (2) 3,974
EBITDA Margin 30% 31% 30%
Total Use of Funds 40,284
Depreciation and Finance Cost 1,189 1,083 10% 1,176 1%
PBT 1,419 1,399 1% 1,581 ‐10%
Tax 274 302 ‐9% 361 ‐24%
PAT before exceptional items 1,145 1,097 4% 1,220 ‐6%
PAT Margin 13% 14% 13%
PAT after exceptional items* 1,115 1,097 2% 1,167 ‐4%
*(Exceptional item (net of tax) in FY24 pertains to transaction costs relating to the acquisition of multi modal facility (Unit 3) of Stelis Biopharma Limited (SBL)
(1 )Other Assets calculated as (Inventories + Trade Receivables + Unbilled Revenues + Advance Tax + FX premium less ( Trade payables + Others current liabilities) at the end of the year
(2) Net cash / (Net debt) calculated as the Cash & cash equivalents (Cash and bank balances + Current investments+ Fixed deposits) less Total debt (Short‐term borrowings + Long‐term borrowings) at the end of the year
*(Exceptional item (net of tax) in FY24 pertains to transaction costs relating to the acquisition of multi modal facility (Unit 3) of Stelis Biopharma Limited (SBL)
Putting Science to Work 29
Shareholding and Share
5 Information
Syngene and Biocon Group
Syngene is an operationally independent publicly listed Biocon Limited, founded in 1978, is an innovation‐led global
subsidiary of Biocon Limited, established in 1993 as India’s biopharmaceuticals company and has majority holding in key
first Contract Research Organization. Company has 25+ years operating entities including Syngene
of experience in novel molecule discovery, development and
manufacturing services
• Product Based
Integrated services:
• Biosimilars
• Discovery research
• Formulations and
• Development *
Compounds
• Manufacturing
• Alternative Therapeutic
small/large molecules
Drugs
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