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The genetic code is the instruction manual that cells

use to translate the information stored in DNA into


proteins. It's like a complex dictionary where
sequences of DNA nucleotides (building blocks) are
matched to specific amino acids (protein building
blocks).
Here's a breakdown of the key points:
 The Players:
o DNA: Deoxyribonucleic acid, the genetic

material that stores the instructions for


building and maintaining an organism. DNA
uses four nucleotide bases: Adenine (A),
Thymine (T), Cytosine (C), and Guanine (G).
o RNA: Ribonucleic acid, a molecule involved

in protein synthesis. There are a few types


of RNA, but messenger RNA (mRNA) is key
in this process. mRNA uses the same bases
as DNA except for Uracil (U) instead of
Thymine (T).
o Amino Acids: The building blocks of

proteins. There are 20 different standard


amino acids used to build proteins in
humans.
o Codons: Three-base sequences of
nucleotides in DNA or RNA. Each codon
codes for a specific amino acid (with some
exceptions).
o Ribosomes: Cellular machines that translate

the genetic code by linking amino acids


together to form proteins.
 The Process:
1. Transcription: DNA is unwound, and a

complementary mRNA strand is copied from


a specific DNA gene segment.
2. Transport: mRNA carries the genetic code

from the nucleus to the cytoplasm (cellular


fluid).
3. Translation: Ribosomes read the mRNA

codon by codon. Transfer RNA (tRNA)


molecules, each carrying a specific amino
acid, match their anticodons
(complementary base sequences) to the
mRNA codons. The ribosome links the
amino acids together in the order specified
by the mRNA codons, forming a protein.
 Key Characteristics:
o Triplet Code: The genetic code is a triplet
code, meaning that a sequence of three
nucleotides (codon) specifies a single amino
acid.
o Degeneracy: Most amino acids are coded
for by more than one codon (except
methionine and tryptophan). This
redundancy helps ensure protein synthesis
can still occur even if there are occasional
errors during copying DNA or RNA.
o Universality: The genetic code is nearly
universal, meaning that the same codons
generally specify the same amino acids in all
living organisms. This allows for the transfer
of genetic information across species.
Understanding the genetic code is fundamental to
genetics, medicine, and biotechnology. It allows
scientists to study how genes control the
development and function of organisms, diagnose
genetic diseases, and develop new therapies.

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