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Cregan Thesis
Cregan Thesis
Cregan Thesis
Danielle M. Cregan
Wells College
CREATIVITY AND BIPOLAR DISORDER 2
CREATIVITY AND BIPOLAR DISORDER 3
Abstract
This paper examines the link between bipolar disorder and creativity. There is a definite link in
the direction of bipolar tendencies fostering creativity, although the mechanisms of this link
remain unclear. Neurology does not provide us with any clear anatomical connection between the
biological bases of bipolar disorder and creativity, though neurotransmitters may be implicated.
Treatment for bipolar disorder includes medication and therapy; certain types of therapy are
more conducive towards creativity, while certain types of medication can encourage or inhibit it.
A therapist absolutely must consider the effect on creativity of the treatment plan they set out for
a creatively inclined bipolar patient, or else they run the risk of noncompliance from the patient
and uselessness for the plan. Bipolar disorder cannot be treated as if it is separate from the
individual experiencing it; at its core, it is a human disorder, and to ignore the human experience
Introduction
The purported link between creativity and mental illness has been widely publicized in
popular culture. The idea of the suffering artist is a popular conception of creativity, but how
much truth is there in this image? For centuries, mental illness and creativity have been
associated. The list of creative people with bipolar disorder is quite long, whether self-admitted
or diagnosed posthumously from their own writings or reported accounts from people who knew
them in life.
There are many famous creative people alive now who admit to having bipolar disorder,
including actor Russell Brand, rapper DMX, actor and author Stephen Fry, musician Macy Gray,
actress and singer Demi Lovato, musician Axl Rose, musician Pete Wentz, actor Dick Van Dyke,
and actress Catherine Zeta-Jones. The list expands upon the inclusion of deceased individuals,
such as the writers Robert Lowell, Theodore Roethke, Sylvia Plath, Anne Sexton, and Virginia
Woolf, and the actors Jeremy Brett, Vivian Leigh, and Jason Robards (Rothenberg, 2001). The
popular singer Amy Winehouse who died in 2011 is a good example of the intersectionality of
bipolar disorder and substance abuse. Many bipolar artists suffer from alcoholism or drug abuse,
including Ernest Hemingway, Jackson Pollock, and Edvard Munch (Rothenberg, 2001). Also,
many bipolar artists either took their own lives or lost them in accidents which could easily have
been prevented, robbing the world of countless potential masterpieces, including Woolf,
Hemingway, Pollock, composer Robert Schumann, and artists Vincent Van Gogh and Arshille
The link between creativity and bipolar disorder is not simply a matter of illness
conferring creativity. A demonstrable link has been shown in several studies using many
CREATIVITY AND BIPOLAR DISORDER 5
assessments of creativity, but this link seems to only be active during hypomanic episodes
(Rybakowski & Klonowska, 2011). During a bout of depression, or at a time when experiencing
full-blown mania, the artist’s creative ability suffers (Rybakowski & Klonowska, 2011). As
Sylvia Plath said, “When you are insane, you are busy being insane—all the time… When I was
Several different areas of the brain are implicated in the expression of bipolar disorder.
There are differences in size, shape, and volume of grey matter, lesions known as
hyperintensities in white matter, abnormalities in the corpus callosum and anterior limbic
network, and glial cell loss and demyelination in many locations in the brain (Brambilla, Bellani,
Yeh & Soares, 2009; Emsell & McDonald, 2009; Palaniyappan & Cousins, 2010). Scientists are
beginning to approach bipolar disorder as having its basis in the dysfunction of neural networks
or systems rather than in individual parts that act alone (Palaniyappan & Cousins, 2010).
isolated to a specific location in the brain. Unlike language, there are no certain areas in the brain
that are specifically associated with creativity, which could be in part because creativity is such a
broad term covering so many kinds of expression. The parts of the brain which ‘light up’ in
functional brain imaging (such as fMRI or PET scans) for a visual artist could be completely
different from the areas activated for a dancer, or an actor, or a writer. Studies examining
creativity focus on very limited expressions of creativity, like writing short poems (Fodor &
Laird, 2004) or designing a pen (Kowatari, Lee, Yamamura, Nagamori, Levy, Yamane, &
Questionnaire (Jung, Segall, Bockholt, Flores, Smith, Chavez, & Haier, 2010). The study of the
CREATIVITY AND BIPOLAR DISORDER 6
neuroanatomy of creativity is still in its infancy, however. As methods for gathering data are
refined and the criteria of creativity are redefined, the findings can and will probably change.
Creative people often find it to be a matter of great importance to preserve their creativity
when undergoing treatment for their disorders. Certain kinds of medication have more of a
negative effect on a person’s creative ability, while other types of medication can leave this
ability mostly unaffected, or perhaps even stimulate it further (Flaherty, 2011). The structures
that underlie creativity in the brain and the neurotransmitters implicated in creativity can be
creativity as a function of a healthy mind, but it is a more urgent matter for people who make a
living from their creative talents to have their ability preserved while receiving proper treatment
for their disorder. Some types of therapy, including cognitive-behavioral and play therapy, are
good for stimulating creative thought and can be particularly helpful to bipolar individuals
The experiences of bipolar individuals who follow creative pursuits are important to
remember when undertaking this topic of study. Delving into the brain and the science behind
bipolar disorder while forgetting about the human side of this equation would be remiss, as the
vital part of comprehending creativity and bipolar disorder is understanding the people who live
with and struggle with this disorder on a daily basis and their experiences working around or
through their inconsistent moods on a quest to create something greater than themselves. Many
bipolar people undergo pharmaceutical treatment or different kinds of therapy in the search for
relief from the symptoms of the disorder. The effects of medication strongly depend on which
medication is being used, but the effects of therapy can be demonstrated to be beneficial for both
CREATIVITY AND BIPOLAR DISORDER 7
the individual and the expression of the individual’s creativity. This paper will examine the link
between creativity and bipolar disorder, with an emphasis on the experiences of bipolar
individuals who participate in creative pursuits, and will explore the effects of medication and
Neuroscience
Many studies have been conducted on the brains of bipolar individuals using different
types of imaging methods, such as magnetic resonance imaging (MRI), diffusion weighted
imaging (DWI), diffusion tensor imaging (DTI), and voxel-based morphometry (VBM) (Emsell
& McDonald, 2009). However, many of these studies have shown contradictory results, either
claiming an increase, decrease, or no change in volume in certain areas of the brain compared to
controls (Emsell & McDonald, 2009). There are, however, certain results which seem to be
supported by most or all studies, which will be the focus of this section.
The first result which has shown up across multiple studies is the presence of white
matter hyperintensities (WMH), which are lesions in white matter in the brain usually associated
with cardiac risk and normal ageing; however, these hyperintensities have been observed in
young and juvenile patients with bipolar disorder (Emsell & McDonald, 2009). WMH are also
observed in other types of affective disorders, including late-onset depression and suicide
(Emsell & McDonald, 2009). Subcortical WMHs are one of the most common findings in MRI
studies of bipolar patients (Brambilla, Bellani, Yeh & Soares, 2009). DWI suggests that
disruptions are found in areas of axonal loss and demyelination, and both DWI and DTI show
disruption of cortical white matter in both adult and juvenile bipolar populations (Brambilla et
CREATIVITY AND BIPOLAR DISORDER 8
al., 2009). Areas which are especially at risk for these disruptions are the frontal lobes, which
generate actions, and consciously register emotions and determine their intensity, as well as the
cingulate-paracingulate cortex, which is closely related to the limbic system and is implicated in
feeling strong emotions and to responding to the emotions of others (Brambilla et al., 2009;
Carter, Aldridge, Page & Parker, 2009). The cingulate cortex is also highly active during periods
of depression (Carter et al., 2009). The anterior cingulate cortex plays a central role in mood
regulation and cognition, making it a target for bipolar disorder studies, which have shown both
increases and decreases in grey matter, and reduced cortical thickness (Emsell & McDonald,
2009).
Another area of the brain in which differences between bipolar and healthy individuals is
found is the corpus callosum. MRI studies show a difference in size, shape, and signal intensity
in the corpus callosum of bipolar individuals in both adult and pediatric patients (Brambilla et
al., 2009). The corpus callosum is vital for inter-hemispheric communications, including the
relaying of emotions between left and right hemispheres, sustained attention, and context
processing, all of which are tasks which can be difficult for a bipolar person (Brambilla et al.,
2009; Carter et al., 2009). As definite identification of white matter composition can only happen
in a post-mortem examination, MRI studies can only reveal so much, but post-mortem studies
have shown reduced density of oligodendroglial cells in the prefrontal cortex, which results in
reduced myelination of neurons, leaving them unprotected (Brambilla et al., 2009). Reduced
myelination causes alterations in connectivity and cognition within the bipolar brain (Brambilla
et al., 2009). The cause of this reduction has not been discovered; however, it is hypothesized
schizophrenia as well as bipolar disorder (Brambilla et al., 2009). Inflammatory cytokines in the
central nervous system have been associated with cognitive disturbance, and perivascular
inflammatory cells can lead to demyelination and axonal loss; the presence of these cells is a
telling predictor of demyelinating diseases like multiple sclerosis (Brambilla et al., 2009). If
Neuroscience of Creativity
There are several problems with trying to pinpoint the source of creativity in the brain.
Creativity is not like language or vision; there is no “creativity area” to be pointed at and neatly
labeled. Creativity itself is a sufficiently broad term to encompass visual art, verbal art, kinetic
art, musical art, gustatory art, and any other venture which could conceivably be considered
artistic. Not only that, but creativity extends its reach beyond the realm of art into science; the
definition of creativity as “the production of something both novel and useful within a given
social context” (Flaherty, 2005) captures scientific breakthroughs like Einstein’s theory of
general relativity and technical revolutions like the design and evolution of the iPod, which
triggered the rise of the tablet. Creativity is generally understood to involve the recombination of
ideas into something new, which implicates working memory, but that is only one step of a
process which involves such disparate ingredients as planning, inspiration, design, and
artistic endeavor. Scans like fMRI and PET require absolute stillness to acquire a clean scan,
which precludes the possibility of analyzing the brain patterns of a dancer, a sculptor, an author,
a chef, an actor, or a musician while they are working at their craft. Also, while inspiration can
be encouraged, it can rarely be predicted; it would be nice if a writer could say, “Hook me up to
the machine, I’m about to be inspired!” but it is neither realistic nor practical to sit around an
MRI machine waiting for inspiration to strike—and who’s to say that the actual moment of
inspiration would last long enough to get the artist into the scanner? Inspiration is usually
described as an instant in which everything comes together. In that case, it might make sense to
expect a moment of inspiration to light up several disparate areas of the brain, possibly ones
which seem to have little connection to each other. However, unless and until we develop
detailed brain scanners that don’t involve inserting people into massive machines, this subject
Still, inspiration is only one very small part of creativity as a general concept; what does
the brain look like in the planning or design stage of a creative endeavor? Kowatari et al. (2009)
designed a study to find out. They compared the brains of university students trained in art and
design to the brains of novice students while both groups of students were coming up with new
designs for pens. This study discovered a difference in the neural networks used by skilled
students compared to novice students while engaged in the design task. While previous studies
communication was crucial, these studies were indirect assessments, and their results were
sometimes contradictory (Kowatari et al., 2009). This study used MRI scans and blood
oxygenated level-dependent (BOLD) signal changes to examine the brains of students while they
CREATIVITY AND BIPOLAR DISORDER 11
were presented with photographs of pens for four seconds each and asked to come up with new
pen designs for those four seconds. In between pictures of pens, the students were presented with
a fixation cross and asked to refrain from designing (Kowatari et al., 2009).
Regions of the brain which were activated in both novice and expert groups included the
right inferior frontal gyrus, the prefrontal cortex, the bilateral occipital cortices, bilateral inferior
temporal cortices, and bilateral hippocampus. In the expert group, only the right prefrontal cortex
and parietal cortex were activated, but the activation was bilateral in the novice group. Only the
novice group experienced activation of the anterior cingulate cortex; there was no significant
activation in that area in the expert group (Kowatari et al., 2009). One further difference was
found in the BOLD signal; the expert group showed a negative BOLD signal change in the
parietal cortex, while the novice group showed a positive signal change (Kowatari et al., 2009).
Since the anterior cingulate cortex was only activated in the novice group, that activation may
represent the difficulty of the task rather than any creative efforts; the areas of the brain which
were obviously implicated in creative efforts in both groups were the prefrontal cortex and the
parietal cortex, and the right side of each was clearly dominant over the left side in the expert
subjects (Kowatari et al., 2009). The parietal cortex is implicated in spatial awareness and
movement, and the prefrontal cortex is involved with emotional control, consciousness, the
ability to multitask, and decision-making (Carter et al., 2009). Interestingly, the anterior
cingulate cortex is activated when feeling emotional rejection or physical pain, as well as when
The only area of the brain which is activated in both bipolar disorder and during creative
endeavors (as measured by this one study) is the cingulate cortex, and in individuals with
CREATIVITY AND BIPOLAR DISORDER 12
experience in that sort of creative endeavor, the cingulate cortex does not activate. Also, the
cingulate cortex is highly active during periods of depression; creativity is actually suppressed
when depression is at its peak. What, if any, is the relationship between bipolar disorder and
creativity in this structure of the brain? Perhaps it is not the structure itself, but the chemicals
within the brain which provide the connection. Most medication does not have an effect on the
physical structure of the brain, but it does have an effect on the neurotransmitters which affect
how the brain works. If the connection is in the chemicals, then the role of medication in treating
bipolar disorder is absolutely vital in preserving creativity while controlling depression and
mania.
When discussing bipolar disorder, the first medication that comes to most people’s minds
is lithium, and for good reason. Lithium was the first drug approved for the treatment of bipolar
disorder, and it has been in use since the 1950s. It is effective for many people, although anyone
on lithium must have frequent blood tests to monitor the level of the drug in their system, as it
has a very narrow therapeutic index (Belmaker, 2004). The effects of lithium are partly due to its
neuroprotective qualities; it increases grey matter volume in both bipolar and healthy subjects,
particularly in the cingulate cortex, prefrontal cortex, and hippocampus (Brambilla et al., 2009).
However, the neuroprotective effects are more obvious in the brains of bipolar patients with
deficiencies in grey matter than in healthy brains which are of normal size and biochemistry
(Brambilla et al., 2009). There are suggestions that lithium and some other mood stabilizers
could promote myelination, but there has not been enough research to support this statement
conclusively (Brambilla et al., 2009). Lithium can have a positive effect on creativity by
CREATIVITY AND BIPOLAR DISORDER 13
stabilizing a bipolar person’s mood enough to allow them to be productive, but once mood
stabilization has been reached, it can have a negative effect on associational productivity and
idiosyncrasy, which are important for synthesizing unrelated ideas into new concepts (Flaherty,
2011). Still, lithium is one of the safer drugs for creativity which treats mania, along with
The midbrain is the area of activation for driving creative motivation via
neurotransmitters sent from neurons to the cortex. Especially important in motivation and
(Flaherty, 2011). It improves working memory, facilitates mental associations, and enhances
mental imagery, including hallucinations (Flaherty, 2011). The goal-directed activity of manic
patients is a result of dopaminergic activity, and dopamine agonist drugs may stimulate
creativity, but they also run the risk of causing impulse control problems, compulsive spending,
patient—spurring poetry from an artist, or sculpture from a dancer (Flaherty, 2011). When trying
to preserve creativity, dopamine agonists are better than dopamine antagonists like neuroleptics,
but caution must be taken to keep from launching the patient into a flurry of manic high-risk
withdrawal from aversive stimuli rather than increasing approach to positive stimuli (Flaherty,
2011). Unfortunately, serotonin can inhibit dopaminergic activity, which can lead to the
inhibition of goal-oriented behavior (Flaherty, 2011). Some of the most commonly prescribed
medications for depression and anxiety are Selective Serotonin Reuptake Inhibitors, or SSRIs.
SSRIs are good for lowering avoidance motivation, making them useful in treating social anxiety
or interpersonal hypersensitivity, but they can also reduce appetitive motivations like curiosity
and libido, which has a negative effect on creativity (Flaherty, 2011). While creative persons
could benefit from caring less about other people’s opinions of them and their work, social
nuance is important for many forms of creativity, and SSRIs may numb a person’s interpersonal
sensitivity to the point where it impacts the work they produce (Flaherty, 2011). There are a few
alternatives to SSRIs which can be taken instead of or in combination with them: bupropion, an
antidepressant dopamine agonist, can improve creativity and combat SSRI apathy even if the
SSRI is continued; lamotrigine, a mood stabilizer, can replace conventional antidepressants for
bipolar patients; also, cognitive-behavioral therapy can be used to treat many of the symptoms of
anxiety and depression that SSRIs are meant to help (Flaherty, 2011).
Pharmaceutical therapy is almost always necessary for the treatment and maintenance of
bipolar disorder. It is important for a prescribing therapist to keep in mind the needs of their
patients; generally speaking, stimulating medications are more helpful for the preservation of
creativity than sedating ones, and the benefits of psychotherapy should not be forgotten in
developing a treatment plan (Flaherty, 2011). There are several kinds of therapy which could be
effective in the treatment of a bipolar person, which will be addressed in the next chapter.
CREATIVITY AND BIPOLAR DISORDER 15
The link between bipolar disorder and creativity has been postulated and explored in
many studies, not only in bipolar people themselves but also in their first-degree relatives.
Creativity is strongly linked to the mood changes that are part of bipolar disorder, especially the
schizotypy in bipolar individuals compared to healthy age-matched individuals using the Revised
Art Scale (RAS) (Barron & Welsh, 1952) and the “inventiveness” battery of the Berlin
Intelligence Structure Test (BIST) (Jäger, Süss & Beauducel, 1997). They also measured the
There was little difference between bipolar and control subjects on the RAS, but markedly higher
results for bipolar individuals on the BIST. Additionally, the study did not show a significant
difference between creativity when measured during a manic episode and during remission.
However, there was a marked difference between creativity when measured during a depressive
episode and during remission, and the negative effect was directly correlated with intensity of the
depressive episode (Rybakowski & Klonowska, 2011). These findings seem to contradict the
commonly made assumption that creativity increases with a manic episode, and actually the
study found that as a manic episode deepened, creativity was slightly negatively impacted. The
time at which a bipolar person’s creativity was at its optimum was during remission of all
symptoms.
Mental Imagery
CREATIVITY AND BIPOLAR DISORDER 16
more vivid and has more of an effect on their mental state, their creativity is heightened. In the
case of bipolar disorder with comorbid anxiety disorder, however, this can be a very negative
thing. Up to 90% of patients with bipolar disorder may present with a comorbid anxiety disorder
within their lifetimes, and there is a hypothesis that symptoms of anxiety may be necessary for
the development and full expression of bipolar disorder (Holmes, Geddes, Colom & Goodwin,
2008).
As mental imagery amplifies and feeds back into emotional states, it can have an effect
on both negative and positive affect. A panic attack can be heightened by a feedback cycle of
negative imagery spiraling the affected person into a deeper state of anxiety, but a hypomanic
state can also be amplified by imagery feeding into mood elevation and pushing affect into a
higher state of positivity. This can quickly rise up into a manic state fuelled by vivid imaginings
of a desired goal which may be overambitious and out of the person’s reach, because manic
people do tend to set extreme goals for themselves while in the grip of a manic episode (Holmes
et al., 2008).
Mental imagery can encompass both past events being relived in a person’s mind, and the
anticipated results of future events as they play out through imaginings; either of these has the
possibility to either elate or alarm a person, and there is evidence that bipolar individuals are
highly susceptible to the change in affect that can be brought about through imagery, especially
uncontrollable, compulsive thoughts (Holmes et al., 2008). These changes in affect can amplify
either end of the emotional spectrum, as well as contribute to the rapid mood swings which are
negative thoughts, compared to the primarily imagistic thinking involved with mental imagery.
Rumination is a process found in both bipolar and unipolar depressive people. Imagining
negative outcomes coupled with the relative absence of imagining positive outcomes is
implicated in mood dysphoria (Holmes et al., 2008). Positively affective imagery is an important
difference between mania and depression, and it is possible that by retraining oneself to produce
positive visualization through cognitive-behavioral therapy, a person could in effect change their
own mood status and remove a depressive state. Creativity would assist greatly in this process; it
is possible that the tendency toward imagery confers creativity just as much as a tendency toward
Cognitive-behavioral therapy. One type of therapy which has often been explored in the
compliance rates for taking psychotropic medication in the bipolar community—estimates range
from 30-50% noncompliance on a regular basis—CBT can be the most effective type of therapy
a patient undergoes (Reilly-Harrington & Knauz, 2005). Also, one must take into account the
fact that even medication-compliant individuals have a 50% chance of having another mood
episode; therapy that helps the individual manage his or her own mood and recognize the
mood swing before they can develop to the point where they start negatively affecting the
individual’s life (Reilly-Harrington & Knauz, 2005). CBT combines cognitive therapy, which
CREATIVITY AND BIPOLAR DISORDER 18
restructures dysfunctional patterns of thinking and replaces irrational beliefs, with behavioral
therapy, which modifies behaviors which are maladaptive, in order to help bipolar patients
achieve several goals. These goals include understanding their disorder in order to self-monitor
and to adhere to treatment better, using coping mechanisms to manage their mood and prevent
relapse, and addressing problems which are specific to the individual which arise from the
CBT can be used in combination with other forms of therapy, like talk therapy and
medication therapy, and in fact has a positive effect on treatment adherence, clinical symptoms,
without adding anything to treatment costs (Szentagotai & David, 2011). The effect generally
falls into the “low to medium but still significant” range, except for treatment adherence, which
has a medium effect. Also, patients who undergo CBT display longer periods of euthymia
(normal, non-depressed affect), significantly fewer mood episodes, better ability to respond to
early warning signs of episodes, and better medication compliance than patients undergoing
standard care of medication and talk therapy (Reilly-Harrington & Knauz, 2005). A type of
therapy that shows benefits to such a wide range of domains without adding anything to the cost
should be more widely adopted when treating bipolar individuals. The specific arena in which
mechanisms, which help to restructure thought processes. For a person who falls into the trap of
negative mental imagery, having the knowledge of how to shift to more positive imagery could
keep him or her from being pulled into a downward spiral of negative cognition. For a person
who doesn’t use mental imagery, perhaps learning to do so would help in maintaining a positive
CREATIVITY AND BIPOLAR DISORDER 19
affect for longer. The emphasis CBT places on monitoring mood state could be very helpful to a
creative bipolar person who is trying to chart the ups and downs of their mood and relate them to
creative output.
Play therapy. Another form of therapy which could be very valuable for fostering
creativity in a bipolar patient is play therapy. The “edge of chaos” theory postulates that
creativity occurs where loosely associated items and ideas come into combination, which
happens readily during mood surgency when positive affect results in defocused attention,
allowing multiple interpretations and ways of approaching the material (Fodor & Laird, 2004).
By encouraging such divergent perspectives and ideas, play therapy can result in more creative
thoughts and allow those with creative talents that might be in remission due to negative affect to
The study conducted by Fodor and Laird (2004) compared the effects of play therapy on
creativity in college students with “bipolar inclination” (a high score on the MCMI-III Bipolar:
Manic scale, but no official DSM diagnosis) to a control group of students, and also compared
the play therapy group with a group that underwent a control which was not meant to raise their
affect. The play therapy that was used was based on techniques designed by Barnes for use with
both children and adults, and included questions like “Tell me about a “healing place” you like to
go to. Why is this place especially comforting to you?” (Fodor & Laird, 2004). The questions
were intended to have a positive effect on affect, without triggering negative memories or
unpleasant emotions. The play therapy also included various art exercises, including “Draw a
favorite thing. It can be anything, as long as it makes you happy” (Fodor & Laird, 2004). The
control group read and interpreted children’s stories from different cultures around the world.
CREATIVITY AND BIPOLAR DISORDER 20
The study measured creativity by having participants write haikus, which were then graded on
several dimensions by students who had completed a literary creativity course (Fodor & Laird,
2004).
The results of the study showed that individuals with bipolar inclination responded to the
play therapy with more creativity than individuals without the inclination, and with much more
creativity than individuals in the control group (Fodor & Laird, 2004). The higher a person’s
score on the Bipolar: Manic scale, the more creativity was revealed in their haiku after
undergoing play therapy. Also, the more a person of bipolar inclination had their mood lifted by
play therapy, the more creative their poetry, in comparison to persons of bipolar inclination
whose affect was less enhanced by the therapy. These results suggest that literary creativity can
be enhanced in bipolar patients by undergoing Barnes’s play therapy procedure (Fodor & Laird,
2004). However, the study also showed that simply having bipolar inclination did not provide a
creative advantage, as those with the inclination in the control group showed roughly the same
level of creativity as those without it in the control group, and around the same level as the
persons without the inclination who underwent play therapy. One question the study could not
answer regarded the duration of the effects of the therapy. Would the creative effect last past the
therapy session? Would a person undergoing this kind of therapy regularly see an enduring
enhancement of their creativity, or do the effects wear off after a few hours or days?
The expression of creativity can also be used as a form of therapy in and of itself. A
biography written about the poet Anne Sexton describes the importance of creative expression in
her treatment: “The sheer existence of the task of writing poetry, through which she could
describe her pain, her confusion, and her observations, provided a critical sense of self-esteem…
CREATIVITY AND BIPOLAR DISORDER 21
writing poetry, in Sexton’s case, became part of the therapy. Any work that elicited approval
would, quite obviously, assist in the repair of self-esteem” (Middlebrook, 1991). Giving a patient
a homework assignment to do some creative writing could be a valuable tool for the treatment of
bipolar disorder. Even the suggestion of keeping a diary could be helpful to a bipolar person,
combining creativity with record-keeping. “Keeping a journal and reading the previous night’s
entry helped me be objective about my mental state” (Powell, 2008). I personally have found this
to be a very helpful technique for accurate mood monitoring over any length of time.
The effect of becoming medicated can be life-changing for a bipolar person. Having
sanity return to you is a wonderful experience. Finally feeling a sense of control over your own
life is almost impossible to describe to a person who has never felt a lack of it. However, it is not
an overnight process, and very often it takes trial and error to discover the right combination of
medications to keep a person stable, during which time the person is subjected to mood swings
and side effects that range from the relatively benign—shaky hands, dry mouth—to the
life-threatening—the potential fatal rash, Stevens-Johnson Syndrome, that can be a side effect of
Lamictal. For a habitually creative bipolar person, the side effects can be pointed and damaging
Most people probably wouldn’t even notice if words came to them more slowly, or if
metaphors had to be hunted down rather than presenting themselves freely. But
for a poet, it’s crucial. For me, the most bothersome side effect of nearly every
someone has turned off the spigot. I can still make the imaginative connections
and find the words eventually, but it takes longer and requires far more
numerous occasions, I’ve tried to do without the drugs, whose other side effects
can be rough. Each time the withdrawal was unbearable, but during the brief
There is a high incidence of noncompliance with medication in the bipolar population when
taken as a whole; no one has examined the rates of noncompliance with specifically creative
bipolar people, but it is far from uncommon for an exasperated, well-medicated, creatively
blocked bipolar individual to go off their medication in a desperate attempt to get back that
divine spark that used to animate their days, however emotionally unbearable those days used to
be. The experiences of Kathleen Maxon, Wells Class of 2012, illustrate this point:
I feel like the medication dampers the intensity of my creativity. Instead of ideas just
coming to me in moments of brilliance, I have to put in a lot more effort and work really hard to
produce the same level of creativity. It's almost like there is a door blocking the thoughts from
getting more creative, more out of control. Sometimes I'll go off of my medication for a few
days if I have a paper to write, just because I know I can produce my best work when I'm not
on the medication. But then it gets out of control, the hypomania that makes me productive
progresses to full blown mania, hallucinations, delusions, paranoia, and not sleeping for
days. Then I crash to a deep depression. So, I feel like I am sacrificing my creativity for
stability. It's frustrating (K. Maxon, personal communication, November 12, 2011).
However, for some, it’s not worth the ease of hypomanic writing to go off medication even for a
CREATIVITY AND BIPOLAR DISORDER 23
few days. Some artists find themselves useless when they’re not properly medicated, and even
though the extremes of emotion may be blunted, at least they can put the words in some kind of
logical order rather than psychotic rambling. Ren Powell (2008) talks about her experience with
medication:
It curbed my exuberance just as it curbed the self-loathing that made me consider suicide.
I found, and find, inspiration for poetry at the edges of that emotional continuum. When
I’m on medication I do sometimes miss the fuzzy hallucinations and emotional highs. And
yet, without the clarity that medication has afforded me, I don’t think I could write the
As both a creative writer and a poet for the majority of my life, since well before I was
diagnosed with rapid-cycling bipolar II disorder, I have been intimately acquainted with
hypomanic writing sprees, the crash of depression, and the long stretch of writer’s block that
accompanies certain types of medication. When I went on medication for the first time in 2004, I
was in the habit of writing sestinas, which are long poems in very strict form. I have not been
able to complete a sestina since I have been medicated, though not for lack of trying. My way
with words was altered in such a way that I can still be clever, but it is harder for me to make a
pun, and I can still write rhyming poetry and adhere to forms, but my favorite form is beyond my
reach now. When I look at the poetry I wrote in 2003 and 2004 and compare it to my work in
2011, what I find is not that my current poetry is lacking in any way, but that it is clear to see that
the way I make metaphors has changed, and my focus has shifted almost entirely to formal
poetry away from free verse. I can remember the fevered nights of writing these long, older
poems, while now my poetry happens at polite hours of the afternoon and early evening.
CREATIVITY AND BIPOLAR DISORDER 24
My creative prose writing has mostly been affected in quantity—no more weekend
binges of writing 20,000 words and barely pausing to sleep or eat—rather than quality. However,
there was a definite alteration when I switched medication in 2009. I was in a deep depression
just wasn’t touching, and I was writing almost nothing at all. When I went to see a new doctor
and a new therapist after moving halfway across the state, my doctor put me on Geodon
(ziprasidone, an atypical antipsychotic mood stabilizer) and Wellbutrin, and gave me Ambien
(zolpidem, a nonbenzodiazepine hypnotic) to help with the insomnia, and within three months of
starting this new combination of medication my creative output was back up to 30,000 words a
month. That was a good limit, giving me time outside of the muse’s grip to take care of myself
I also believe that my creativity has benefited from therapy. My old therapist (who was
also my psychiatrist) engaged in pure talk therapy, just letting me babble on for an hour with
brief interjections to tell me I was doing something wrong and exactly how she thought I should
fix it. She was not very helpful, and I did not trust her at all by the time I moved away. My new
therapist is a woman who does a lot of work with children; the first time I met with her, she had
me tell her about myself, and then we spent some time doing play therapy with a sandbox. She
has had me do various creative things during our sessions in an effort to express myself more
completely, and I do feel like I have benefited from these exercises. We do not do them very
often, as I find it very easy to simply talk through the entire hour I meet with her each month, but
seeing the results of the study on play therapy has encouraged me to ask her if we can
CREATIVITY AND BIPOLAR DISORDER 25
I believe it is important for every bipolar person to be involved in their own treatment.
Not everyone will look up or understand the direct effects of medication on the brain, and it’s not
a good idea for an uneducated person to ask for a drug simply because they have heard about it,
but with the Internet making information so readily available and discussion forums making it so
easy for bipolar people to talk to each other, anyone should be able to ask their therapist to
therapy into their sessions. If a person is being bounced from SSRI to SSRI without finding any
benefit to any of them, there are several other classes of antidepressants or mood stabilizers they
could try that may help more, and without the apathy induced by that class of drug.
Discussion
Studies have shown a definite link between bipolar disorder and creativity. However, the
mechanisms of that link remain unclear. Without a specific structure in the brain clearly
implicated in both the pathology and the process, it seems safer to say that the connection is
found in neurotransmitters, which are most often the target of psychoactive medication. The
effects of different types of medication on creativity should be considered as well as the effects
they have on affect; medication should be selected to be effective in treating the mood disorder
above all else, but one which has less of a negative effect on creativity perhaps should be
favored.
The popular image of the tortured artist may have some root in fact, but the periods of a
creative bipolar person’s life during which they are actually most creative are during remission of
all symptoms and during mild hypomanic episodes. There is a negative effect on creativity
CREATIVITY AND BIPOLAR DISORDER 26
during both depressive episodes and manic episodes, so it is in the best interest of a creative
self-monitoring of mood states in order to stop a mood episode before it has a chance to really
take off.
Other forms of therapy can be used alongside pharmaceutical therapy to great effect.
Cognitive-behavioral therapy can actually increase compliance with medication therapy and
provides the bipolar person with excellent coping strategies and mental tools to use in managing
their own mood. Play therapy can stimulate the bipolar person’s creativity during a therapy
session, although the duration of the positive effects has not been studied. Also, creative
exercises can be used as a tool in therapy; having clients write poems about how they feel or
keep a journal detailing their mood on a daily basis could be very valuable over the long term,
and even if they aren’t diagnostically helpful, the creative expression could be a very positive
Although some creative bipolar individuals may be tempted to go off their medication in
order to access the levels of creativity they had before being medicated, it is important to
encourage them to stay medication-compliant at all times. Working with them to find a
combination of medications which might preserve their creativity better is one way to encourage
medication compliance; adding CBT or play therapy to their treatment plan may also help.
The neuroanatomy of creativity is a recent field of study, and the studies which have been
undertaken are so disparate that it is difficult to generalize from their findings. Perhaps if further
studies adhered to a certain measure of creativity, or a specific way of imaging the brain, this
field could develop more rapidly and with more certainty in results across the board. More
CREATIVITY AND BIPOLAR DISORDER 27
studies explicitly examining the connection between bipolar disorder and creativity could return
interesting results; perhaps a study focusing on the role of neurotransmitters could be undertaken.
From the results already shown by completed studies, a shift in commonly used therapy towards
greater inclusion of CBT principles and play therapy exercises could be greatly beneficial to
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