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Toxicology MCQ
Toxicology MCQ
Toxicology MCQ
3- Which term refers to the amount of a toxic substance that enters the body?
a) Dose
b) Exposure
c) Toxicity
d) Concentration
a) Acute toxicity
b) Chronic toxicity
c) Environmental toxicity
d) Occupational toxicity
a. Age
b. Pre-existing medical conditions
c. Nutritional status
d. All of the above
a. A comparison of the minimally lethal dose (LD01) to the maximally effective dose
(ED99).
b. The amount of a pharmaceutical that can be given before toxicity first appears.
a) toxicant
b) toxin
c) xenobiotic
d) poison
11- Which of the following toxicity can occur due to single exposure?
c).Sub-chronic toxicity
d).Chronic toxicity
a. Whether exposure has caused an effect, threshold or the effect, and the rate of buildup of
the effect with increasing dose levels.
13- The dose level at which a toxic effect is first encountered is known as the:
a. Threshold Dose
b. First Dose
c. The estimated dose level that will produce 50% deaths in groups of animals
administered a specific dose.
16- The professional activities of toxicologists fall into three main categories:
17- Five Identical experimental animals are treated with 1 mg of one of the following
toxins. The animal treated with which toxlc is most likely to die?
c. nicotine (LD(D50=1mg/kg).
a) The time it takes for the substance to be eliminated from the body
b) The time it takes for the substance to reach peak concentration in the blood
c) The time it takes for the substance to be absorbed into the bloodstream
21- The no observed adverse effect level (NOAEL) is also known as the no effect level (NEL).
a. True
b. False
22- The term toxicant is used when talking about toxic substances that are produced by or
are a by-product of human-made activities
a. True
b. False
a) Inhalation
c)Ingestion
d)Injection
25- Which of the following is NOT a factor that can influence the toxic kinetics of a
substance?
b) Genetic factors
a)Age
b)Gender
c)Genetic makeup
27- Which of the following enzymes play crucial role in detoxification of the chemicals?
A .Digestive enzymes in the gastrointestinal tract destroy all the chemicals entering into the body.
d. B&C
d. B & C
E. A & C
d. Target organ
30- Which of the following factors can Influence the toxicodynamics of a substance?
b)Duration of exposure
c) Individual susceptibility
31- The process by which a toxic substance is converted to a less toxic or inactive form is
known as:
3) Detoxification
b) Biotransformation
c)Conjugation
d) Metabolism
32- Liver is the main metabolizing organ in the body. Which of the following statement is
true in association with toxicant metabolism and reduction of toxicity?
a. Liver alone metabolizes all the toxicants and does not need any further assistance
d. All the chemicals are removed from the body through bile, after metabolism in the liver.
33- Which of the following will have the most damaging effects?
34- Which of the following factors may influence an individual's susceptibility to toxic
substances?
a)Age
c) Nutritional status
a) Temperature
b) Surface area
c)Duration of exposure
37- You have worked at a chemical facility for 10 years. The facility does not require
protective equipment, and you have developed a number of serious health affects in the
last 7 years. You are possibly experiencing what type of exposure?
a. Chronic
b. Acute
38- You are worried about contamination of vegetables grown in contaminated soils. What
type of toxicologist would you contact?
a.Descriptive
b. Environmental
C. Regulatory
d. Food
39- The larger the amount of exposure and the greater the dose, the greater the observed
response, or effect.
a. True
b. false
40- Which of the following factors can affect the distribution of a toxic substance within the
body?
43- Most of the chemicals are excreted out by the kidneys through urine which are the
other organs or modes involved in excretion of chemicals?
a) Potentiation
b) Synergism
c) Additivity
d) Acute Toxicity
e) Agonism