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Technique Notes
Technique Notes
TECHNIQUES
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CONTENT
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ADVERSED EFFECTS
Properties of contrast media that cause adverse effects:
a) Osmolarity
b) Ionic charge (ionic CM)
c) Chemical structure
d) Lipophilicity
Incidence of adverse reaction (non-ionic iodinated CM): Rare (1%)
Mild Majority
Severe – very severe 0.044%
2. Vascular toxicity
a) Venous
Effects Causes
(i) Pain at injection site Perivenous injection
(ii) Immediate limb pain Stasis of CM in vein
(iii) Delayed limb pain Thrombophlebitis (toxic effect on endothelium)
b) Arterial
- Effects: Pain & burning sensation
- Causes: Arterial endothelial damage & vasodilatation
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4. Cardiovascular toxicity
Effects Causes
a) Arrhythmia, ↑ vagal activity → Depression of SA node & AV node
Bradycardia, asystole
b) Hypotension HOCM
→ ↑ Serum osmolarity
→ Water influx into vascular compartment (↑ blood volume)
→ ↑ Cardiac output
→ Transient ↑ SBP
→ Reflex peripheral vasodilatation
→ More prolonged ↓ BP
Injection into right heart → Transitory pulmonary HPT & systemic hypotension
Injection into left heart → Transient systemic HPT, followed by more prolonged ↓ BP
5. Haematological toxicity
Effects Causes
a) Haemolysis Mixture or RBC wt CM (↑ concentration), in syringe
→ RBC damage
→ Further haemolysis upon re-injection of damaged RBC into blood stream
b) Thrombus formation Mixture of blood wt contrast (more common wt LOCM), in syringe
→ Blood in contact wt foreign material (CM & wall of syringe)
→ Activation of coagulation pathways
→ Further thrombosis upon re-injection of the CM into blood stream
c) RBC aggregation ↑ Concentration of CM
However, disaggregation occurs easily → No significant clinical effect
d) Coagulopathy CM impairs blood clotting & platelet aggregation
CM potentiate the action of heparin
e) Capillary occlusion HOCM
→ Water leaves RBC via osmosis
→ RBC becomes more rigid & less deformable
→ Less easy to pass through capillaries, may cause occlusion
f) Transient eosinophilia Occur 24 – 72 hrs after CM injection
g) Sickle cell crisis Precipitated by CM
6. Neurotoxicity
Effects: Convulsions (rarely)
Causes: CM crosses blood brain barrier → Osmolarity & chemotoxic effects
7. Thyroid function
Effects: Thyrotixicosis (esp in patient wt non-toxic goiter or pre-existing thyrotoxic symptoms)
8. Idiosyncratic reactions
→ Anaphylactoid reactions (Non-IgE mediated)
Severity:
a) Minor reactions Do not interfere wt examination, but require patient reassurance
b) Intermediate reactions Interfere wt examination, but do not requirement treatment
c) Major reactions Interfere wt examination, require treatment
d) Fatal reactions Very rare (1.1 – 1.2 per million)
Predisposing factors:
a) Previous contrast reaction → ↑ 6x risk
b) Previous allergic reaction, requiring medical treatment
c) Bronchial asthma → ↑ 6-10x risk
d) Intra-venous injection > Intra-arterial injection
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Effects:
a) Skin
(i) Urticaria
(ii) Necrotizing skin lesions More in patient wt CKD
b) CNS
(i) Tingling sensation
(ii) Fever, rigors
c) GIT
(i) Metallic taste
(ii) Nausea, vomiting
(iii) Abdominal pain
(iv) Desire to empty rectum
d) GUT
(i) Perineal burning
(ii) Desire to empty bladder More in female
e) CVS
(i) Flushing(vasodilatation)
(ii) Angioneurotic oedema Usually facial region
(iii) Arrhythmias
(iv) Hypotension Usually transient & mild
May a/w reflex tachycardia OR bradycardia (vagal overactiviety)
f) Respiratory system
(i) Sneezing
(ii) Bronchospasm
(iii) Non-cardiogenic pulmonary oedema
g) Delayed-onset reactions Rashes, headache, parotid gland swelling
(1hr – 1wk after CM injection)
Mechanisms:
a) Histamine release
(i) Direct CM (more with HOCM)
→ Histamine released from mast cells & basophils
(ii) Indirect CM
(via complement activation) → Activation of complement system
→ Formation of anaphylatoxins
→ Histamine released from mast cells & basophils
- Effects: Urticaria
Metallic taste,
Flushing, angioneurotic oedema, arrhythmias, hypotension
Sneezing, bronchospasm
b) Protein binding (CM are weak protein binders)
(i) Acetylcholinesterase inhibition CM
→ Binds wt acetylcholinesterase
→ Inhibits the action of acetylcholinesterase
→ ↑ Acetylcholine in synapses
→ ↑ Cholinergic effects (Parasympathetic activities)
Effects: Urticaria
Abdominal pain, desire to empty rectum / bladder
Flushing, bradycardia, hypotension
Bronchospasm
(ii) Cellular immunity activation CM
→ Binds wt immune receptors on T-cells
→ Activation of T-cells (cellular immunity)
→ Release of cytokines (interleukins, interferons, TNF)
→ Acute reaction
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c) Chemotoxicity
(i) Intrinsic chemotixicity of the CM molecules
(ii) Hyperosmolarity
d) Stimulation of autonomic nervous system
CM → Cross blood brain barrier
→ Stimulation of hypothalamus & limbic lobe
→ ↑Autonomic activity
Pre-ganglionic Post-ganglionic
Neurotransmitter Receptors Neurotransmitter Receptors
Sympathetic
a) General Ach Cholinergic NA Adrenergic (α, β)
b) Sweat glands Ach Cholinergic Ach Cholinergic
c) Smooth muscle of Ach Cholinergic Ach Cholinergic
blood vessels
d) Adrenal medulla Ach Cholinergic Release Adrenaline -
(Adrenal medulla) into blood stream
Parasympathetic Ach Cholinergic Ach Cholinergic
(i) Muscarinic (M1-M5)
(ii) Nicotinic (α, β, γ, δ, ε)
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Gastrograffin
Material: Diatrizoic acid (Diatrizoate)
Properties: Ionic HOCM (water soluble)
Indications:
a) Fluoroscopy When barium is contraindicated (confirmed / suspected perforation)
Meconium ileus
b) CT scan As oral & rectal contrast (Dilution 3%)
Contraindications:
a) Patient at risk of aspiration
b) Patient with known allergies to gastrograffin
Complications:
a) Anaphylactoid reactions
b) Pulmonary oedema if aspirated
c) Dehydration, especially in children (due to its hyperosmolarity)
d) May precipitate hyperchlorhydric gastric acid
LOCM
Examples: Ultravist, Omnipaque, Iopamero
Properties: Non-ionic LOCM (water soluble)
Indications:
a) Fluoroscopy When barium is contraindicated (confirmed / suspected perforation)
When gastrograffin is contraindicated (patient at risk of aspiration)
b) CT scan As IV contrast
Contraindications: Patient with known allergies to LOCM
Complications: Anaphylactoid reactions
Gases
Indications: Used in conjunction wt barium to produce ‘double contrast’ effect
Properties:
a) Produce adequate volume of gas (200 – 400 mls)
b) Do not interfere wt barium coating
c) Do not produce bubble
d) Dissolve rapidly
Types:
a) CO2 (via carbex granules) - For upper GI studies (oesophagus, stomach, duodenum)
- Carbex granules / powder are administered orally
b) Room air - For lower GI studies (large bowel)
- Room air is administered per rectum, via hand pump attached to the enema tube
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Preparation:
Gadolinium Oral & IV (with gadolinium compounds made soluble by chelation
Particles of iron oxide:
(i) Large particles Oral suspension
(ii) Small particles (SPIO) IV
(iii) Ultrasmall particles (USPIO) IV
Precaution:
Pregnancy Should not be routinely given
No reports on teratogenic effect
But insufficient evidence to support its safety
Breast feeding Breast feeding can continue normally
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GADOLINIUM
Types of CM:
a) Extracellular fluid (ECF) agents - Circulate within vascular system
(i) Gd-diethylenetriaminepenta-acetic acid (DTPA) - Excreted unchanged by kidneys
Dimegluminegadopentetate Magnevist - Do not cross blood brain barrier
(ii) Gadodiamide (Gd-DTPA-bismethylamide) Omniscan
Usage: General
(iii) Gadoteridol (Gd-DO3A) ProHance
b) Liver agents - Gd chelates wt altered excretory pathway
(i) Gd-BOPTA Multihance - Taken up by hepatocytes
(ii) Gd-DTPA Primovist Excreted unchanged by hepatobiliary system
(iii) Manganese-DPDP (Non-gadolinium) Telescan
Usage:
Detect liver lesions with no hepatocytes (liver mets)
Characterize liver lesions wt hepatocytes (HCC)
c) Blood pool agents - Remain longer in vascular system
(i) Gadofosveset trisodium Vasovist
Usage: Vascular imaging
Dosage of ECF gadolinium agents: 0.1 – 0.2 mmol/kg
Adverse reactions:
a) Acute adverse reactions
Effects (i) Urticaria
(ii) Nausea, vomiting
(iii) Dizziness, confusion
(iv) Dyspnoea, chest discomfort, palpitation
(v) Anaphylactoid shock
Predisposing factors (i) Previous contrast reaction
(ii) Previous allergic reaction, requiring medical treatment
(iii) Bronchial asthma
b) Delayed adverse reactions
(i) Renal impairment - At standard doses: No significant renal impairment
- At ↑ doses to give equivalent x-ray attenuation: More nephrotoxic than iodine
(ii) Nephrogenic systemic fibrosis (NSF) - ↑ Collagen deposition, in skin & other tissues
- 2 – 3 mths after contrast injection
- Mechanism: Unknown
- Renal impairment is the main trigger
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IRON OXIDE
Superparamagnetic CM, consists of particles of iron oxide
Types of CM:
a) Large particles
b) Small particles (SPIO) Predominantly shorten T2 relaxation time
c) Ultrasmall particles (USPIO) Predominantly shorten T1 relaxation time
Preparation:
a) Large particles Oral suspension
b) Small particles (SPIO) IV
c) Ultrasmall particles (USPIO) IV
Mechanism:
a) Small particles (SPIO) Taken up by reticulo-endothelial cells in liver & spleen
→ Hypointense signal in normal liver & spleen, on T2 images
Not taken by lesions wt no reticulo-endothelial cells
→ Retain high signal intensity, on T2
Usage: Detect liver tumour (HCC)
b) Ultrasmall particles (USPIO) Taken up by reticulo-endothelial cells in bone marrow & LN
→ Hyperintense signal, on T1 images
Usage: Imaging of bone marrow & LN
2. Negative agents
Types a) Ferrite
b) Barium sulphate (60 – 70% w/w)
Mechanism Shorten T2 relaxation time → Hypointense signal on T2 images
Disadvantages a) Image distortion in high concentrations
b) Required dose for ferrite is potentially lethal
→ Chelation needed to ↓ iron absorption
3. Biphasic agents
Types Klean-Prep (contains macrogol, KCl, NaCl, NaSO4, NaHCO3)
Mechanism
Disadvantages
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Types of CM:
a) Levovist Microbubbles of air, coated within palmitic acid, in galactose solution
b) SonoVue Microbubbles of sulphur hexafluoride, in aqueous suspension
Usage:
a) Assess macro & microvasculature in different tissue
b) Identify & characterize lesions in liver, spleen, pancreas, kidney, prostate, ovary & breast
c) Assess patency of fallopian tube at HSG
d) Assess VUR at voiding US
e) In echocardiography
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Pre-ganglionic Post-ganglionic
Neurotransmitter Receptors Neurotransmitter Receptors
Sympathetic
a) General Ach Cholinergic NA Adrenergic (α, β)
b) Sweat glands Ach Cholinergic Ach Cholinergic
c) Smooth muscle of Ach Cholinergic Ach Cholinergic
blood vessels
d) Adrenal medulla Ach Cholinergic Release Adrenaline -
(Adrenal medulla) into blood stream
Parasympathetic Ach Cholinergic Ach Cholinergic
(i) Muscarinic (M1-M5)
(ii) Nicotinic (α,β,γ,δ,ε)
2. Glucagon
Pharmacology Polypeptide hormone, produced by α-Langerhans cells in pancreas
→ ↑ blood glucose & smooth muscle relaxation in GIT
Dose Barium meal Adult – IV 0.3mg, Paeds – 0.5 – 1 μg/kg
Barium enema Adult – IV 1mg, Paeds – 0.8 – 1.25 μg/kg
Indications a) When buscopan is contraindicated
b) If combine barium meal & follow-through, as it does not interfere wt small bowel transit time
Advantages & Advantages: Disadvantages:
Disadvantages a) More potent than Buscopan a) Cost - Expensive
b) Short duration of action (15mins) b) Relatively slower onset of action
c) Do not interfere small bowel transit time
c) Allergic reaction (as it is a protein)
d) GIT: Nausea, vomiting, abdominal pain
e) HypoK+
Contraindications a) Phaeochromocytoma : Glucagon causes tumour to release cacholamines → Adrenergic crisis, HPT
b) Insulinoma (relative) : Glucagon causes hyperglycemia, followed by reflex hypoglycemia
c) Glucagonoma (relative)
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3. Metoclopramide (Maxolon)
Pharmacology Anti-dopaminergic agent→ Stimulate gastric emptying & small bowel transit
Dose Oral / IV / IM / rectal 20mg
Indications Barium follow-through
Advantages & Advantages: Disadvantages:
Disadvantages a) Anti-emetic a) Extrapyramidal side effects
b) Rapid onset of action
Contraindications a) Confirmed / suspected bowel obstruction
b) Phaeochromocytoma: Maxolon causes tumour to release cacholamines → Adrenergic crisis, HPT
c) Caution in Parkinson’s disease
d) Caution in patient on antipsychotics
2. Heparin
Pharmacology Anticoagulant
Dose IV bolus: 60 – 100 μ/kg (Small size: 3,000 μ Large size: 5,000 μ)
Prolonged procedure: Add 1,000 μ
Indications Prevention of vascular & pericatheter thrombosis, during endovascular procedure
Disadvantages Bleeding
Reversal IV Protamine Sulphate(1mg for every 100μ remaining heparin, maximum 50mg)
Contraindications a) Bleeding disorder & tendency
b) PUD
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2. Benzodiazepin
Pharmacology Diazepam (Valium) Midazolam (Dormicum)
Dose Tab 10mg, 2hrs before procedure Adult: IV 2.5 – 7.5mg (usually 5mg given)
IV 0.3 mg/kg Paeds: Rectal 0.35 – 0.45 mg/kg
Indications a) Sedation
b) Anxiolysis
Disadvantages a) CNS: Headache, drowsiness, dizziness
b) GIT: Nausea, vomiting
c) GUT: Incontinence, urinary retention
d) Respiratory depression
e) Hypotension
Reversal IV Flumazenil 0.3 – 0.8mg
Contraindications a) Myasthenia gravis
b) Acute narrow angle glaucoma
c) Acute alcohol intoxication
d) Caution: elderly, COPD (risk of resp depression), CKD, CCF (risk of cardiac arrest)
3. Opioids
Pharmacology Pethidine Fentanyl
Dose Oral 50 – 150mg, 4hrly Transdermal / Oral / IV / IM:
IV 0.5 – 1 mg/kg 1 – 50 μg/kg (usually 1 – 2 μg/kg used)
Indications Analgesia for moderate to severe pain Analgesia for moderate to severe pain
(50x potent than morphine)
Disadvantages a) CNS: Headache, drowsiness, dizziness a) Respiratory depression
b) GIT: Nausea, vomiting b) Bradycardia
c) Respiratory depression
d) Bradycardia
Reversal IV Naloxone 0.01 mg/kg (0.1 – 0.2mg, Max 0.4mg)
Contraindications Caution in patient wt head injury, renal & liver impairment
4. Lignocaine
Pharmacology Amide derivative of diethylaminoacetic acid (DEAAC)
Dose Infiltration / intrathecal / epidural: 0.3 mg/kg → 200mg (20mls of 1% solution)
Indications Local anaesthesia → Reversible neural blockade
Disadvantages Neurotoxicity: Perioral numbness, tinnitus, dizziness, convulsion
Contraindications a) Hypovolemia
b) Heart block
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Chapter 2 GENERAL
RADIOGRAPHY
15
This is a ……
1. Type of examination
2. Type of projection
3. Indication
4. Contra-indication
5. Technique
a) General - Confirm correct patient, test & indication
- If female of reproductive age, confirm LMP
- Proper exposure
- Remove foreign objects at region of interest
- Gonadal shield
b) IR - IR size
- Grid / non-grid
- Correct annotation: Patient ID, anatomical marker
c) Exposure technique - kV
- mAs
d) Patient position
Respiration
e) Tube position
f) CR
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CHEST
A. PA & AP view
PA AP
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DISCUSSION
1. Reason of high kV technique in CXR:
a) Chest has high subject contrast: Difference btw bone / heart / lungs
- ↑ kV allows better penetration of bones, heart & lung bases → Visualization of fine lung markings
- ↑ kV will ↓ dynamic range → Allows visualization of mediastinum & lungs with 1 exposure
b) ↓ mAs (exposure time) → ↓ Motion artifacts
c) ↓ mAs → ↓ Patient dose
3. Hidden areas
a) Apices - PA: Partially obscured by ribs, clavicles & soft tissues
- Lat: Limited visualization
b) Hilum - PA: Central lesions are superimposed
- Lat: Better visualization
c) Mediastinum (retro-cardiac region) - PA: Central lesions are superimposed
- Lat: Better visualization
d) Diaphragms & costophrenic angles - PA: Lung bases& posterior sulcus are partially obscured by posterior diaphragm
Worse if under-inspiration
e) Bones & costal cartilages - PA: Lung lesions may be obscured
- Expiratory, AP & oblique films may be helpful
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Indication - To localize a lesion seen on PA/AP CXR - To assess lung apices (Pancoast tumour, TB)
- To clarify lobar collapse/consolidation → Clavicle projected above lung apices
- To explore a retrosternal or retrocardiac shadow - Medial aspect of 1st 4 ribs
- To confirm the presence of encysted fluid in the oblique
fissure (pseudotumour)
IR 35 x 43 cm 35 x 43 cm
Grid Grid
Exposure 110 – 120 kV (usually + 10kV from PA view) 110 – 120 kV
2 – 3 mAs 2 – 3 mAs
Position
- Erect
- Standing 30cm away from IR, back facing IR
- Side of interest facing IR (typically left):
- Then lean back to IR
Left lung is more obscured in PA view
- Back of head, neck & shoulder against IR
Less magnification of heart in left lateral view
- Chin up - Shoulders rolled forward
- Both arms raised above head - Hands on the hips
- MSP ║ IR, MCP ∟ IR
- Full inspiration, suspend
- Full inspiration, suspend
Tube Horizontal beam Horizontal beam
FFD: 180cm FFD: 180cm
CR - MCP - MSP
- Level of T7 - Level of T7 (Midway btw sternal notch & xiphoid process)
Collimation - Upper border: Lung apices 4 sides to lung fields
- Lower border: Costophrenic angles
- Sides: Anterior & posterior skin margins
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1. Soft tissue of shoulder 11. Lt upper lobe bronchus 20. Mitral valve
2. Trachea 12. Main pulmonary artery 21. Tricuspid valve
3. Scapula 13. Descending aorta 22. Pulmonary veins
4. Sternal angle 14. Pulmonary valve 23. Lt ventricle
5. Aortic arch 15. Pulmonary veins 24. Retrocardiac space
6. Sternal body 16. Aortic valve 25. IVC
7. Aorto-pulmonary window 17. Lower lobe bronchus 26. Gastric bubble
8. Ascending aorta 18. Lt atrium 27. Lt hemidiaphragm
9. Rt upper lobe bronchus 19. Rt ventricle 28. Rt hemidiaphragm
10. Retrosternal space
DISCUSSION
1. Difference btw right & left lateral film
Right lateral Left lateral
a) Heart size ↑ Magnification ↓ Magnification
b) Lung details ↑ Rt lung radiographic detail (Rt lung closer to IR) ↑ Lt lung radiographic detail (Lt lung closer to IR)
c) Hemidiaphragm - Rt hemidiaphragm lower than Lt
- Rt hemidiaphragm meets with Rt posterior ribs
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D. Oblique view
Anterior oblique view (Typically !!) Posterior oblique view (LPO & RPO)
HUKM practice posterior oblique !!!
RAO LAO
Indication - Trauma: Rib fracture (Ant ribs: Ant oblique, Post ribs: Post oblique)
- Lung pathology, hilum
- Lateral constophrenic angles
- Cardiac configuration
a) RAO (equivalent to LPO): To assess Lt side
b) LAO (equivalent to RPO): To assessRt side
IR 35 x 43 cm 35 x 43 cm
Grid Grid
Exposure 120 kV 120 kV
2 – 3 mAs 2 – 3 mAs
Position RAO LAO
- Erect,
AP projection (IR posteriorly related)
- Region of interest: Facing IR
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ABDOMEN
A. AP (supine) / KUB & PA (prone) view
IR 35 x 43 cm
Grid
Exposure 70 – 80 kV (Intermediate kVp)
30 mAs, short exposure time
Position AP (supine) / KUB PA (Prone)
↓ Gonadal dose (if kidney is not the interest)
1. Spleen
2. Liver
3. Left kidney
4. Right kidney
5. Subcutaneous fat
6. Abdominal muscles
7. Preperitoneal fat
8. Psoas
9. Iliac crest
10. Ilium
11. Sacrum
12. Obturator internus
13. Urinary bladder
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B. AP (erect) view
AP (erect)
Indication:
Air under diaphragm
IR 35 x 43 cm, Grid
Exposure 70 – 80 kV
30 mAs, short exposure time
Position
DISCUSSION
1. Difference btw AP& PA film
AP PA
a) Pelvic brim Rounder, wider Oval & narrow
b) Sacrum & SI joint Wider Narrow
c) Iliac wings Smaller Bigger
d) Obturator foramen Oval Rounder, > vertically orientated
2. Fat in abdominal cavity
Advantages Greater tissue absorption for organ surrounded by fat (eg. Kidneys)
Disadvantages Scatter radiation
3. Differences btw AXR & KUB XR
a) Different indication
b) For KUB, closer side-side collimation, but symphysis pubis must be included inferiorly
c) KUB requires bowel-prep
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Exposure 70 – 80 kV 80 – 85 kV
30 mAs, short exposure time 50 mAs, short exposure time
Position
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H. Gonion
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C. PNS 1. Lateral
2. PA / OF
a) PA 15o (Caldwell)
3. Parieto-acanthial / OM
a) Waters – Open mouth
4. SMV
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1. Lateral view
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1. Parietal bone – Outer table 10. Cribriform plate 19. Maxillary sinus
2. Diploe 11. Anterior clinoid process 20. Opening of EAC
3. Parietal bone – Inner table 12. Posterior clinoid process 21. Coronoid process of mandible
4. Coronal suture 13. Nasal bone 22. Foramen magnum
5. Groove of middle meningeal art 14. Sphenoid sinus 23. Zygomatic process
6. Frontal sinus 15. Zygomatic bone 24. Hard palate
7. Pituitary fossa 16. Clivus 25. Nasopharynx
8. Greater wing of sphenoid 17. Ethmoid sinus 26. Soft palate
9. Lambdoid suture 18. Temporal bone – Petrous part 27. Mandible
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IR 24 x 30 cm
Grid
Exposure 70 – 80 kV
20 mAs
Position
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Towne
Indication 1. Skull + sella turcica
Structures to be seen:
Petrous pyramids, foramen magnum, dorsum sellae, posterior clinoid processes, occipital bone,
post part of parietal bones, semicircular canal, IAM, Arch of atlas, arcuate eminence
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- Usually supine
- Head extended over the end of table
- Head supported with IR
- IOML ║ IR, IOML ∟ CR
- MSP ∟ IR
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Line 1:
- Look for widening of the zygomatico-frontal sutures
- Fractures of the superior rim of the orbits
- "Black-Eyebrow" sign due to orbital emphysema
- Opacification / air-fluid level in the frontal sinuses
Line 2:
- Look for fractures of the superior aspect of the zygomatic arch
- Fractures of the inferior rim of the orbits
- Soft tissue shadow in the superior maxillary antrum
- Fractures of the nasoethmoid bones and medial orbits
Line 3:
- Look for fractures of the inferior aspect of the zygomatic arch
- Fractures of the lateral maxillary antrum
- Opacification / air-fluid level in the maxillary sinuses
- Fractures of the alveolar ridge
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B. Optic Canal XR
IR 18 x 24 cm (crosswise)
Grid
Exposure 80 kV
20 mAs
Position - Erect (more common) or prone, front facing IR
- OML raised by 35o
- MSP 55o to IR
- Suspend respiration
Tube Horizontal (Erect), Vertical (Prone)
FFD 100cm
CR Down side orbit
Remarks Optic canal seen end on in the lower ½ adjacent to lateral margin of orbit
C. Jugular Foramen XR
IR 18 x 24 cm (crosswise)
Exposure 70 – 80 kV
20 mAs
Position - Erect or supine, back facing IR
- OML ║ IR
- MSP ∟ IR
- Suspend respiration
Tube Horizontal (Erect), Vertical (Supine)
FFD 100cm
Angle CR 20o caudally
CR 2.5cm distal to mandibular symphysis
Remarks - Jugular foramen not superimposed with mandible
- Angle of mandible & lateral border of skull are equidistant
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D. Zygomatic Arches
- Basic views: Tangential (Bilateral or Unilateral), AP axial / OM / Modified Towne, SMV
1. Tangential view
IR 18 x 24 cm
Grid
Exposure 60 – 70 kV
6 mAs
Position
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IR 24 x 30 cm
Grid
Exposure 70 – 80 kV
20 mAs
Position
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E. Mandible
- Basic views: PA / OF, AP axial / FO, Axio-lateral oblique
CR CR Angle To see ……
Level of lips 0o (CR ∟ IR) Mandibular body
Midway btw TMJs 30o cranially Rami & condylar process of TMJ
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2. Axio-lateral oblique
IR 18 x 24 cm
Grid
Exposure 70 – 80 kV
20 mAs
Position
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IR 18 x 24 cm
Grid
Exposure 70 – 80 kV
14 mAs
Position
Tube Horizontal
FFD 100cm
Angle CR 25o caudally
CR If mastoid is the interest: Mastoid tip in contact with IR
If TMJ is the interest: TMJ in contact with IR (5cm superior to TMJ away from IR)
Remarks - TMJ anterior to EAM
- Close mouth: Condyle in mandibular fossa
- Open mouth: Condyle inferior to articular tubercle
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G. Nasal Bone XR
- Basic views: Lateral, Tangential, Parieto-acanthia / OM / Waters
Indication Trauma: Fracture
IR 18 x 24 cm (crosswise)
Exposure 55 kV
3 mAs
Position
Tangential Lateral
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H. Orthopantomogram
Indication - Dental assessment
- To assess lamina dura & periodontal membrane
- TMJ or mandibular pathology
IR Curved non-grid cassette
Exposure 65 – 70 kV
10 mAs (Long exposure time: 12 – 20sec)
Position - Erect
- Head immobilized wt temporal plates
- Chin rest on chin rest
- Incisors bit the bite block
- Lips closed
- Tongue lifted up to hard palate
Tube Horizontal beam
X-ray tube & bulky move from side to side (in opposite direction) to a fulcrum
CR Middle detector is in line wt infra-orbital line
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This is a ……
1. Type of examination - Skull radiograph
2. Type of projection - done in lateral projection
3. Indication - To look for
4. Contra-indication - No absolute contraindication
5. Technique To perform this examination,
a) General - Confirm correct patient, test & indication
- If female of reproductive age, confirm LMP
- Proper exposure
- Remove foreign objects at region of interest
- Gonadal shield
b) IR - IR size of
- Gridded cassette
- Annotation: Patient ID, anatomical marker
c) Exposure technique - 60 – 70 kV
- Short mAs
d) Patient position - Erect, IR at the side of patient
- Interpupillary line (IP) ∟ IR
MCP ∟ IR
MSP ║ IR
Respiration - Suspend respiration
e) Tube position - Horizontal beam
- FFD: 100cm
f) CR - 5cm above tragus
g) Collimation - Apply 4-sided collimation
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SPINE
A. Cervical Spine
1. AP + Open mouth view
AP AP – Open mouth
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- Erect of supine,
- Erect of supine,
- Lateral, shoulder against IR
- Lateral, shoulder against IR
- Arm & shoulder (facing IR) raised,
- Chin slightly raised
elbow flexed & forearm rest on the head
- Shoulder depressed
- Arm & shoulder (away from IR) down
- MCP ∟ IR
- No swallowing
- No swallowing
- Suspend respiration
- Suspend respiration
Tube Erect: Horizontal beam to sideway Erect: Horizontal beam to sideway
Supine: Lateral horizontal beam (from sideway) Supine: Lateral horizontal beam (from sideway)
Vertical IR Vertical IR
FFD 120 – 150 cm FFD 120 – 150 cm
CR - MCP Level of T1 (2.5cm above jugular notch anteriorly)
- Level of C4 (Upper margin of thyroid cartilage)
Collimation - C1 – C7 (minimum), Superior ½ of T1 - C4 – T3 (minimum)
- Surrounding soft tissue - Surrounding soft tissue
Remarks - Visualized spinous process - Visible vertebral bodies & intervertebral disc spaces of
- Intervertebral disc space open C4-T3
- Superimposed Rt & Lt pillars & zygo-apophyseal joints - Humeral head & arm (away from IR) should be distal to
of each cervical vertebra T4 or T5
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3. Oblique view
- Typically posterior oblique (However, anterior oblique ↓ thyroid dose)
- HUKM practice posterior oblique !!!
LPO RPO
Indication To assess neural foramina
a) RPO (equivalent to LAO): To assess left side (neural foramina)
b) LPO (equivalent to RAO): To assess right side (neural foramina)
IR 18 x 24 cm
Grid
Exposure 70 – 80 kV
10 mAs
Position
- Right or left posterior oblique
- AP projection (IR posteriorly related)
- MSP rotated 45o
- Chin slightly raised
- Head in lateral position,
looking away from the side being imaged
- No swallowing
- Suspend respiration
* Marker usually placed at the side being
assessed
RPO LAO
Tube Vertical beam
FFD 120 – 150 cm
Posterior oblique: Angle 15o cranially Anterior oblique: Angle 15o caudally
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Cervical spine – AP
1. Foramen magnum
2. Atlanto-dental joint
3. Dens of C2
4. Occipital bone
5. Transverse process
6. Vertebral arch
7. Lateral mass of C1
8. Atlanto-axial joint
9. Spinous process (bifid)
10. Uncovertebral joint
11. Overlapping articular process
12. Uncinate process
13. Pedicle
14. Transverse process
15.Intervertebral disc space
16. Transverse process of T1
17. Radiolucent band of trachea
18. 1st rib
1. Anterior arch
2. Odontoid process
3. Atlas C1
4. Mandible
5. Body of C2
6. Facet joint
7. Inferior articular process
7. Superior articular process
9. Transverse process
10. Contralateral pedicle
11. Pedicle
12. Intervertebral foramen
13. Spinous process
14. Ribs
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B. Thoracic Spine
1. AP & Lateral view
IR 35 x 43 cm, Grid
Exposure 80 – 90 kV, 12 mAs
Upper thorax: Overexposed Anode heel effect method
Lower thorax: Underexposed Wedge filter
Position AP Lateral
AP Lateral
1. Tubercle of 1st rib 9. Body of vertebra 1. Scapula 10. Inferior vertebral end plate
2. Neck of the rig 10. Inferior vertebral end plate 2. Anterior superior margin 11. Head of the rib
3. 1st rib 11. Transverse process 3. Posterior superior margin 12. Intervertebral disc space
4. Trachea 12. Pedicle 4. Anterior inferior margin 13. Intervertebral foramen
5. Clavicle 13. Spinous process 5. Posterior inferior margin 14. Transverse process
6. Head of the rib 14. Diaphragm 6. Vertebral body 15. Spinous process
7. Paravertebral line 15. Inferior articular process 7. Superior articular process 16. Diaphragm
8. Superior vertebral end plate 16. Superior articular process 8. Inferior articular process 17. Facet joint
9. Superior vertebral end plate
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2. Oblique view
- Typically posterior oblique
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C. Lumbar Spine
1. AP & Lateral view
AP Lateral
IR 35 – 43 cm
Grid
Exposure 80 kV
15 mAs
Position - Supine, back facing IR - Lateral recumbent position,
side facing IR (below)
- Arms at sides or on chest
- Hips & knees flexed (↓ lumbar curvature) - Support beneath lower back (↓ lumbar curvature)
- ASIS equidistant from table top - Hips & knees flexed, with support btw knees
- MSP ∟ Table - Spine║ IR
- End of expiration, suspend - End of expiration, suspend
Tube Vertical beam
FFD 100cm
CR - Midline - Long axis of spine
- Level of iliac crest - Level of iliac crest
Collimation - T12 – S1 (minimum), entire sacrum - T12 – Entire sacrum
- SI joints & psoas muscles
Remarks - Spinous process in midline - Intervertebral joint spaces are open
- Rt & Lt transverse process same length - Superimposed greater sciatic notches & posterior
- SI joint & spinous process are equidistant vertebral bodies
AP Lateral
1. Body of vertebra 8. Inferior articular process 1. Superior vertebral end plate 7. Superior articular process
2. Superior vertebral end plate 9. Transverse process 2. Inferior vertebral end plate 8. Inferior articular process
3. Inferior vertebral end plate 10. Spinous process 3. Intervertebral foramen 9. Iliac crest
4. Intervertebral disc space 11. Pedicle 4. Spinous process 10. Promontory
5. Facet joint 12. Sacroiliac joint 5. Transverse process 11. Sacrum
6. Psoas 13. Sacrum 6. Intervertebral disc space
7. Superior articular process 14. Sacral foramina
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2. Oblique view
- Typically posterior oblique
Indication To assess pars interarticularis – “Scotty dog” appearance
a) RPO (equivalent to LAO): To see Rt zygapophyseal joints, Rt pars interarticularis
b) LPO (equivalent to RAO): To see Lt zygapophyseal joints, Lt pars interarticularis
IR 35 – 43 cm
Grid
Exposure 80 kV
15 mAs
Position
1. Body of vertebra
2. Intervertebral disc space
3. Ribs
4. Interarticular part
5. Intervertebral disc space
6. Lamina
7. Ipsilateral transverse process
8. Contralateral transverse process
9. Pedicle
10. Superior articular process
11. Intervertebral foramen
12. Inferior articular process
13. Spinous process
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D. Scoliosis series
IR 35 – 43 cm
Grid
Exposure 80 kV
15 mAs
Position First IR: Second IR:
- Erect - Block placed under foot (convex side of curvature)
- Spine aligned - Gonad shields
- Arms at side
- Lower margin 3-5cm below iliac crest
- End of expiration, suspend
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UPPER LIMB
Indications:
1. Bones 2. Joints 3. Soft tissue
a) Trauma: Fracture a) Trauma: Dislocation / subluxation a) Foreign bodies
b) Infections b) Arthritic changes b) Fat pad
c) Architectural changes c) Swelling
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IR 24 x 30cm
Grid
Exposure 65 – 75 kV
6 mAs
Position
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4. Stryker’s view
Indication To demonstrate Hill-Sach deformity
IR 24 x 30cm
Exposure 65 – 75 kV
6 mAs
Position
- Supine
- Arm extended fully
- Elbow flexed
- Hand rest on the head
- Suspend respiration
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5. Clavicle
AP Axial
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AP
Axial
1. Sternoclavicular joint
2. Clavicle
3. Acromion
4. Acromioclavicular joint
5. Manubrium of sternum
6. Coracoid process
7. Greater tubercle of humerus
8. Bicipital groove
9. Lesser tubercle of humerus
10. Humeral head
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B. Humerus
1. AP & Lateral
IR 35 x 43cm,
Grid if > 10cm
Exposure 75 kv, 6 mAs
Position AP Lateral
AP Lateral
1. Clavicle 1. Coronoid process
2. Lateral process (Scapula) 2. Glenoid fossa
3. Acromion (Scapula) 3. Clavicle
4. Greater tubercle 4. Lesser tubercle
5. Lesser tubercle (Humerus)
6. Humeral Head 5. AC joint
7. Anatomical neck 6. Humeral head
8. Bicipital groove 7. Acromion
9. Surgical neck 8. Cortex
10. Humerus 9. Humeral shaft
11. Deltoid tuberosity 10. Coronoid fossa
12. Lateral epicondyle 11. Radial head
13. Olecranon process 12. Olecranon fossa
14. Olecranon (Ulna) 13. Radius
15. Medial epicondyle 14. Trochlea
16. Trochlea 15. Capitellum
17. Radial head 16. Ulna
18. Radius 17. Olecranon
19. Ulna 18. Coronoid process
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C. Elbow
1. AP & Lateral view
IR 24 x 30 cm (divided into 2), crosswise
Non-grid
Exposure 60 kV,
6 mAs
Position AP Lateral
AP Lateral
1. Humerus 10. Trochlea 1. Humerus 8. Lateral epicondyle
2. Olecranon fossa 11. Humero-radial joint 2. Coronoid fossa 9. Radius
3. Medial epicondyle (Humerus) 12. Humero-ulnar joint 3. Coronoid process 10. Humero-ulnar joint
4. Lateral epicondyle (Humerus) 13. Coronoid process 4. Radial head 11. Olecranon
5. Apex of medial epicondyle 14. Radial head 5. Radial tuberosity 12. Humero-radial joint
6. Olecranon 15. Proximal radioulnar joint 6. Olecranon fossa 13. Ulna
7. Lateral margin of trochlea 16. Radial neck 7. Medial epicondyle
8. Medial margin of trochlea 17. Radius
9. Capitellum 18. Ulna
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D. Forearm
1. AP & Lateral view
IR 30 x 35 cm, Non-grid
Exposure 60 kV, 6 mAs
Position AP Lateral
AP Lateral
1 – 4 Prox carpal row 1 – 4 Prox carpal row
1. Pisiform 1. Triquetrum
2. Scaphoid 2. Scaphoid
3. Triquetrum 3. Pisiform
4. Lunate 4. Lunate
5. Radial styloid 5. Radiocarpal jt
6. Ulnar styloid 6. Ulnar styloid
7. Radiocarpal jt 7. Ulna
8. Distal radioulnar jt 8. Radius
9. Radius 9. Interosseous
10. Interosseous membrane
membrane 10. Radial neck
11. Ulna 11. Radial head
12. Radial tuberosity 12. Coronoid process
13. Prox radioulnar jt 13. Coronoid fossa
14. Radial neck 14. Trochlea
15. Coronoid process 15. Humerus
16. Radial head 16. Olecranon
17. Humero-ulnar jt 17. Olecranon fossa
18. Humero-radial jt
19. Trochlea
20. Capitellum
21. Olecranon
22. Lateral epicondyle
23. Medial epicondyle
24. Olecranon fossa
25. Humerus
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E. Wrist
1. Basic views 2. Scaphoid views
a) PA a) PA
b) Lateral b) PA with ulnar deviation
c) Oblique c) PA with radial deviation (Not done in HUKM !!!)
d) Posterior oblique
e) Lateral
a) PA
Position
- Same as PA view
- Hand moved towards ulnar side
- Radial & ulnar styloid processes are
equidistant from IR
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- Same as PA view
- Hand moved towards radial side
- Radial & ulnar styloid processes are
equidistant from IR
DISCUSSION
1. In HUKM, only 4 views performed: PA, PA with ulnar deviation, lateral & PA oblique
2. Scaphoid fracture: Waist (65&), Proximal pole (15%), Distal pole (8%), Tubercle (8%), Distal articular (2%)
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AP Lateral
1. Proximal phalanx 10. Pisiform 1. Proximal phalanx 7. Scaphoid
2. 5th metacarpal 11. Scaphoid 2. Metacarpals 8. Triquetrum
3. Carpo-metacarpal jt 12. Lunate 3. Trapezoid 9. Pisiform
4. Trapezoid 13. Radial styloid 4. Hook of hamate 10. Lunate
5. Trapezium 14. Radiocarpal joint 5. Trapezium 11. Radial styloid
6. Capitate 15. Ulnar styloid 6. Capitate 12. Ulnar styloid
7. Hook of hamate 16. Radioulnar joint
8. Hamate 17. Radius
9. Triquetrum 18. Ulna
1. Metacarpal 8. Lunate
2. Hamate 9. Pisiform
3. Trapezoid 10. Radial styloid
4. Capitate 11. Ulnar styloid
5. Trapezium 12. Radius
6. Scaphoid 13. Ulna
7.Triquetrum
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IR 18 x 24 cm
Non-grid
Exposure 55 – 65 kV
4 mAs
Position
1. Pisiform 6. Lunate
2. Trapezium 7. Capitate
3. Hook of hamate 8. Trapezoid
4. Triquetrum 9. Hamate
5. Scaphoid
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F. Hand
- Basic views: PA & anterior oblique
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2. Posterior oblique
1. Distal interphalangeal jt
2. Head of proximal phalanx
3. Prox interphalangeal jt
4. Prox phalanx
5. Base of prox phalanx
6. Metacarpo-phalangeal jt
7. Metacarpal
8. Metacarpal head
9. Sesamoid
10. Metacarpal base
11. Capitate & Hamate
12. Trapezoid
13. Triquetrum
14. Trapezium
15. Lunate
16. Scaphoid
17. Ulnar styloid
18. Radial styloid
19. Distal ulna
20. Distal radius
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G. Fingers
1. Fingers
PA Lateral Oblique
IR 18 x 24 cm, Non-grid
Exposure 50 – 60 kV, 2 mAs
Position
2. Thumb
PA Lateral Oblique
IR 18 x 24 cm, Non-grid
Exposure 50 – 60 kV, 2 mAs
Position
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LOWER LIMB
Indications:
1. Bones a) Trauma: Fracture
b) Infections
c) Architectural changes
2. Joints a) Trauma: Dislocation / subluxation
b) Arthritic changes
3. Soft tissue a) Foreign bodies
b) Fat pad
c) Swelling
A. Pelvis
1. AP view
IR 35 x 43 cm, crosswise
Grid
Exposure 75 – 85 kV
12 mAs
Position
- Supine, back facing IR
- Arms at side or across the chest
- Hips slightly abducted & internally rotated (15o)
→ Femoral necks ║ IR
- MSP ∟ IR
If externally rotated:
- NOF foreshortened
- Lesser trochanter in profile
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IR 35 x 43 cm, crosswise
Grid
Exposure 75 – 85 kV
12 mAs
Position
- Supine
- Both knees flexed 90o, externally rotated 60o
- Both plantar surface of feet together
- MSP ∟ IR
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3. Sacroiliac Joint
PA AP (Patient unable to prone) Posterior oblique
IR 24 x 30 cm, lengthwise, Grid
Exposure 80 – 90 kV, 9 mAs
Position - Prone, front facing IR - Supine, back facing IR - Supine, back facing IR
- Arms raised above - Arms raised above - Trunk rotated 30o,
- PSIS equidistant to IR - ASIS equidistant to IR rising the affected side,
- MSP center to IR - MSP center to IR Supported with radiolucent pad
- MSP ∟ IR - MSP ∟ IR
Tube Vertical beam Vertical beam Vertical beam
FFD 100cm FFD 100cm FFD 100cm
Angle caudally Angle cranially Angle caudally
Male (15o), Female (20o) Male (15o), Female (20o) Male (15o), Female (20o)
CR - Midline - Midline 2.5cm medial to elevated ASIS
- Level of PSIS - Level btw ASIS & upper border of
symphysis pubis
Remarks - Visualized SIJ & sacrum - Same as PA view - Upside SIJ open
- Spinous process in center of a) LPO: Rt SIJ open
vertebral body b) RPO: Lt SIJ open
- No overlap of iliac wing & sacrum
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B. Hip Joint
1. AP & Lateral view
AP (≈ Pelvis AP view) Lateral
IR 24 x 30 cm, Grid
Exposure 75 – 85 kV, 12 mAs
Position
1. Sacroiliac joint
2. ASIS
3. Sacrum
4. AIIS
5. Intergluteal fat stripe
6. Acetabular roof
7. Acetabular convexity
8. Fat stripe med to glut minimus
9. Ischial spine
10. Ant acetabular rim
11. Acetabular floor
12. Post acetabular rim
13. Fovea of femoral head
14. Femoral head
15. Ilioischial line
16. Kohler’s teardrop figure
17. Greater trochanter
18. Terminal line
19. Femoral neck
20. Superior pubic ramus
21. Intertrochanteric crest
22. Obturator foramen
23. Fat stripe med to iliopsoas
24. Ischial tuberosity
25. Lesser trochanter
26. Femur
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Indication Suspect acetabular fracture, reverse Judet’s view if patient unable to prone
IR 24 x 30 cm
Grid
Exposure 75 – 85 kV
12 mAs
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C. Femur
1. AP & Lateral view
AP Lateral
IR 35 x 43 cm
Grid
Exposure 70 – 80 kV
12 mAs
Position
Tube Vertical
FFD 100cm
CR Midpoint of femur
Collimation - Proximal: Hip joint (May not be able to include both joints all the time)
- Distal: Knee joint
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D. Knee
1. AP & Lateral view
IR 18 x 24 cm 18 x 24 cm
Grid if > 10cm Grid if > 10cm
Exposure 65 – 75 kV 65 – 75 kV
5 mAs 5 mAs
Position AP Lateral
AP
1. Femur
2. Patella
3. Lateral femoral epicondyle
4. Medial femoral epicondyle
5. Growth plate
6. Lateral femoral condyle
7. Medial femoral condyle
8. Lateral tibial condyle
9. Medial tibial condyle
10. Medial & lateral tubercles of
intercondylar eminence
11. Epiphyseal plate
12. Fibular head
13. Tibia
14. Fibula
15. cortex
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Lateral
1. Femur
2. Patella
3. Posterior fat
4. Patellar ligament
5. Infrapatellar fat pad
6. Lateral femoral condyle
7. Tibial plateau
8. Intercondylar eminence
9. Tibial tuberosity
10. Fibular head
11. Fibularneck
12. Tibia
2. AP Standing
Indication:
To assess knee joint spce
IR 18 x 24 cm, Grid
Exposure 65 – 75 kV, 5 mAs
Position
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- Supine
- Affected knee flexed 60o
Supported wt radiolucent pad
- Knee over IR
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Tube:
- Vertical beam
- FFD 120 – 150cm (↓ magnification)
- Angle 60o caudally
CR:
- Midpoint btw patellae (CR ║ long axis of patella)
Position: - Prone, IR under knee
- Affected knee flexed 90o
Tube: - Vertical beam
- FFD 120 – 150cm (↓ magnification)
- Angle 15o cranially
CR: Patello-femoral joint
Collimation Patella & patello-femoral joint
Remarks - Too much flexion: Patella tracked over lateral femoral condyle
- In adequate flexion: Tibial tuberosity over shadow retropatelar joint
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IR 35 x 43 cm
Non-grid
Exposure 65 – 75 kV
6 mAs
Position
Tube Vertical
FFD 100cm
CR Midpoint of leg (btw knee & ankle)
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F. Ankle
1. AP & Lateral
IR 24 x 30 cm (divided into 2) 24 x 30 cm (divided into 2)
Non-grid Non-grid
Exposure 60 – 70 kV 60 – 70 kV
6 mAs 6 mAs
Position AP Lateral
1. Tibia
2. Fibula
3. Growth plate
4. Fibular notch
5. Ankle
6. Medial malleolus
7. Lateral malleolus
8. Trochlea of talus
9. Subtalar joint
10. Calcaneus
11. Navicular
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1. Fibula
2. Tibia
3. Achilles tendon
4. Growth plate
5. Ankle
6. Trochlea of talus
7. Medial malleolus
8. Talus
9. Lateral malleolus
10. Talar neck
11. Talar head
12. Talo-navicular joint
13. Posterior process of talus
14. Sinus tarsi
15. Navicular
16. Lateral process of talus
17. Calcaneus
18. Medial cuneiform
19. Post tuberosity of calcaneus
20. Cuboid
21. Base of 5th metatarsal
2. AP Mortise view
IR 24 x 30 cm (divided into 2)
Non-grid
Exposure 60 – 70 kV
6 mAs
Position
- Sitting or supine
- Leg extended
- Foot (posterior aspect) above IR
- Foot in natural position (not true AP position)
- Limb medially rotated 20o
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IR 24 x 30 cm (divided into 2)
Non-grid
Exposure 60 – 70 kV
6 mAs
Position
- Sitting or supine
- Leg extended
- Foot (posterior aspect) above IR
- Foot dorsiflexed, held wt a strip of gauze
- Plantar surface ∟ IR
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G. Foot
- Basic views: PA & anterior oblique
1. AP & Oblique view
AP Oblique
IR 24 x 30 cm
Non-grid
Exposure 60 – 70 kV
2 mAs
Position
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2. Lateral view
IR 24 x 30 cm, Non-grid
Exposure 60 – 70 kV, 2 mAs
Position Lateral Standing lateral
- Lateral recumbent position, on the affected side - Standing, weight equally distributed
- Lateral aspect of foot over IR - Medial aspect of foot facing vertical IR
- Plantar surface ∟ ankle
Tube Vertical beam
FFD 100cm
CR Base of 3rd metatarsal
Collimation - Distal end tibia / fibula
- Entire foot & ankle
Remarks - Superimposed metatarsals, except 5th metatarsals (below others)
- Talo-tibial joint open
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1. MTP joint
2. Tarso-metatarsal joint
3. Medial cuneiform
4. Middle cuneiform
5. Lateral cuneiform
6. Cuneonavicular joint
7. Navicular
8. Talo-calcaneo-navicular joint
9. Tibia
10. Ankle
11. Fibula
12. Talus
13. Posterior process of talus
14. Distal phalanx
15. Middle phalanx
16. Proximal phalanx
17. Sesamoid
18. Metatarsal
19. Base of 5th metatarsal
20. Cuboid
21. Calcaneo-cuboid joint
22. Calcaneus
23. Posterior tuberosity of calcaneus
1. Talus 9. Navicular
2. Lateral melleolus 10. Achilles tendon
3. Lateral process of talus 11. Calcaneus
4. Os trigonum 12. Cuboid
5. Subtalar joint 13. Base of 5th metatarsal
6. Posterior process of talus 14. Posterior tuberosity of calcaneus
7. Sinus tarsi 15. Plantar aponeurosis
8. Sustentaculum tali
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Chapter 3 BREAST
IMAGING
92
A. Mammography
Indications 1. Focal signs in women > 35yrs, as triple assessment (clinical, radiological, pathological)
2. Assessment of confirmed breast Ca
- Multi-focal (>1 lesion in the same quadrant)
- Multi-centric (>1 lesion in different quadrant)
- Bilateral disease
3. Breast Ca follow-up
- No more frequent than annually
- Less frequent than biennially
4. Metastatic malignancy of unknown origin
5. Screening for asymptomatic women,
a) with low risk btw 40-49yrs (annually), btw 50-75yrs (annually or biennially)
b) with moderate / high risk of breast Ca, < 40yrs
(i) 1st or 2nd degree relative with breast Ca at the age < 50yrs
(ii) H/o breast or ovarian Ca
(iii) H/o breast atypia on biopsy at the age < 40yrs
c) who underwent radiotherapy for Hodgkin’s disease when < 30yrs
6. Screening for women on HRT
a) Prior to commencement of HRT
b) On HRT >5yrs: Annually / biennial
Not indicated 1. Asymptomatic women, without familial history of breast Ca, aged < 35yrs
2. Investigation for generalized sign/symptom (cyclical mastalgia, non-focal pain, lumpiness)
3. Routine investigation of gynaecomastia
4. To assess integrity of silicone implants
5. Patients wt ataxia-telangiectasia mutated (ATM) gene mutation, wt resultant ↑ sensitivity to radiation exposure
Equipment Mammographic unit with:
a) Dual focus x-ray tube
Focal spot size (mm2) Indication
0.3 General use
0.1 Magnification view
b) Dual filtration: molybdenum / rhodium
c) Choice of rotating target material: molybdenum / rhodium / tungsten
d) Interchangeable buckys
18x24 cm
24x30 cm
e) Automated exposure control (AEC)
f) Carbon fibre table top wt reciprocating / oscillating grid (average rid ratio 5:1)
g) Magnification assembly (magnification factors 1.8 / 2.0)
h) Contact spot compression
Technique - Imaging of both breasts
- Gonad shield (esp in CC view)
- Exposure factors:
kV 25 – 35
mA Focal spot 0.3mm2 100 mA
Focal spot 0.1mm2 40 mA
Exposure time 2 sec
- Compression, resulting in
a) ↓ Breast thickness → ↓ Scatter & noise → ↑ Resolution
b) Uniformity of breast thickness → Even penetration
c) Immobilization of the breast → ↓ Blurring
d) ↓ Radiation dose
- Additional features:
a) Spot compression → To remove overlapping composite tissue
b) Magnification → To provide morphological analysis
- Views:
a) Standard views (i) Medio-lateral oblique (MLO)
(ii) Cranio-caudal (CC)
b) Additional views (i) Extended CC
(ii) Lateral: Medio-lateral / latero-medial
(iii) Axillary tail
Additional views are done when any uncertainties arise on standard views
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- The only projection that demonstrates all breast tissue on a single image
- Best visualize: Upper outer quadrant, axillary tail, tissue adjacent to chest wall
- Criteria for a good MLO image:
a) Visualized entire breast tissue
b) Symmetrical both sides: A line from nipple to pectoralis muscle, difference in both sides < 1cm
c) Nipple in profile
d) Visible skin pores
e) Pectoralis major muscle extending to / below nipple line, convex anteriorly
f) Fibroglandular tissue > Retroglandular tissue
g) Inframammary fat fold (inframammary angle) is seen
- Visualize: All medial tissue, majority of lateral tissue excluding axillary tail
- Criteria for a good CC image:
a) Visualized all medial tissue & as much of lateral tissue as possible
b) Symmetrical both sides
c) Nipple in profile
d) Visible skin pores
e) Pectoralis major muscle is seen in ⅓ of the posterior edge of the breast
d) Retroglandular fat is seen
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5. Spot compression
6. Magnification
- Breast placed on platform, at a defined distance from grid holder (air gap technique)
Area of interest compressed
Image field collimated as small as possible
- Use small focal spot, remove grid
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Findings:
Breast Composition A: Almost entirely fatty
B: Scattered fibroglandular density
C: Heterogenously dense, may obscure masses
D: Extremely dense
Architectural Distortion Distorted parenchymal with no visible mass
Asymmetry Asymmetry, focal, global, developing
Mass Shape Round, oval, irregular
Margin Circumscribed, obscured, microlobulated, indistinct, spiculated
Density Fat, low, equal, high
Calcifications Morphology Typically benign
Suspicious: Amorphous, course heterogenous, fine pleomorphic,
fine linear, fine linear branching
Distribution Diffuse, regional, grouped, linear, segmental
Associated features Skin retraction, nipple retraction, skin thickening, trabecular thickening, axillary adenopathy
A. Breast Composition
BIRADS density Description
A Almost entirely fatty
B Scattered fibroglandular density
C Heterogenously dense, may obscure masses
D Extremely dense
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C. Asymmetry (Unilateral deposits of fibroglandular tissue not conforming to the definition of a mass)
1. Asymmetry Area of fibroglandular tissue, visible on only 1 projection, mostly d/t superimposed normal breast tissue
2. Focal asymmetry Visible on 2 projections, hence a real finding rather than superposition
3. Global asymmetry Asymmetry over at least ¼ of the breast and is usually a normal variant
4. Developing asymmetry new, larger and more conspicuous than on a previous examination
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E. Calcifications
1. Morphology
a) Typically benign Skin, vascular, coarse, large rod-like, round / punctate (< 1mm), rim, dystrophic, milk of calcium, suture
* Exception: an isolated group of punctuate calcifications that is new, increasing, linear or segmental in
distribution or adjacent to a known cancer
b) Suspicious Amorphous (4B), course heterogenous (4B), fine pleomorphic (4B),
fine linear (4C), fine linear branching (4C)
2. Distribution
a) Diffuse Distributed randomly throughout the breast
b) Regional Occupying a large portion of breast tissue > 2 cm greatest dimension
c) Grouped (historically cluster) Few calcifications occupying a small portion of breast tissue (≥ 5 calcifications within 1cm)
d) Linear Arranged in a line, which suggests deposits in a duct
e) Segmental Suggests deposits in a duct or ducts and their branches
F. Final Assessment
BIRADS category Management Likelihood of cancer
0 Poor examinations Wait for prior examinations / NA
Need additional imaging Recall for additional imaging
1 Negative Routine screening Essentially 0%
2 Benign Routine screening Essentially 0%
3 Probably benign Short interval follow-up (6 months) > 0% to ≤ 2%
4 Suspicious Tissue diagnosis
4A > 2% to ≤ 10%
4B > 10% to ≤ 50%
4C > 50% to < 95%
5 Highly suggestive of malignancy Tissue diagnosis ≥ 95%
6 Known biopsy proven malignancy Surgical excision when clinical appropriate 100%
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B. Ultrasound
Indications 1. Focal signs in women < 35yrs, as triple assessment (clinical, radiological, pathological)
2. Adjunct to mammographic screening in women > 35yrs
3. Assessment of confirmed breast Ca
- Assess initial tumour size
- Response to neo-adjuvant therapy
4. Diagnosis / drainage / follow-up of breast abscess
5. Assessment of implant integrity
6. US guided biopsy of breast lesion / LN
7. US guided hook wire localization of breast lesion
Technique - Position:
a) Supine For examination of the medial aspect of the breast
b) Oblique / lateral For examination of the lateral aspect of the breast & axilla
- Raised the arm on the side to be examined, placed behind the head
- Views:
a) Upper inner quadrant
b) Upper outer quadrant
c) Lower inner quadrant
d) Lower outer quadrant
e) Retro-areolar region
f) Axillary tail
- Look for LN
Remarks
Findings:
Breast Composition Homogeneous – fat, homogeneous – fibroglandular, heterogeneous
Mass Shape Round, oval, irregular
Margin Circumscribed
Not circubscribed (angular, microlobulated, indistinct, speculated)
Orientation Parallel, non-parallel
Echo pattern Anechoic, isoechoic, hypoechoic, hyperechoic,
complex solid/cystic, heterogeneous
Posterior features No features, enhancement, shadowing, combined pattern
Calcifications In mass, outside mass, intraductal
Associated features Architecture distortion, duct changes, skin thickening, skin retraction, oedema,
vascularity, elasticity
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C. MRI
Indications 1. To look for recurrence, 6mths post-breast conservation surgery, for breast Ca
2. Adjunct to mammographic screening in women with high risk of breast Ca
3. Assessment of confirmed breast Ca: Response to neo-adjuvant therapy
4. To clarify equivocal / suspicious mammographic / US findings
5. Investigation of occult breast Ca (Malignant axillary LN but normal breast triple assessment)
6. Assessment of implant integrity
Contra-Ix CIx for standard MRI & IV contrast media
Contrast IV Gadolinium 0.1-0.2 mmol / kg (except in assessment of implant integrity)
Preparation - IV line
- Prone, head first
- Breasts placed in surface coil
Planes: Coronal
1. Coronal Total slice: 13, SL: 4-6mm
2. Axial Total slice: 13, SL: 4-6mm
3. Axial FLASH Total slice: 11slices x 8times (88), SL: 4-6mm
Sequence:
1. T1 TR: 500ms, TE: 15ms
2. T2 fat sat TR: 2,000ms, TE: 110ms
3. T1 FLASH TR: 100ms, TE: 5ms
Axial
Protocol 1. Pre-contrast
Coronal: T1, T2 fat sat (total slice: 15, SL: 4 – 6mm)
Axial: T1, T2 fat sat
→ 11 T1-axial images containing lesion are then imaged wt dynamic FLASH sequence
IV Gadolinium 0.1-0.2 mmol / kg, followed by IV NS 20mls
(Non-enhanced scanning is adequate for assessment of implant integrity)
Findings:
Focus < 5mm (Cannot be specified)
Mass Shape Round, oval, lobulated, irregular
Margin Smooth, irregular, spiculated
↑ T1 Lymph node, fat necrosis, hamartoma
↑ T2 fat sat Cyst, lymph node, fibroadenoma, fat necrosis, colloid carcinoma
Enhancement Homogeneous, heterogeneous, rim, septa
Kinetics Type 1, 2, 3
Non mass-like enhancement Distribution Focal (punctate), linear, ductal, segmental, regional, diffuse
Pattern Punctate (focal), homogeneous, heterogeneous, clumped
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A. Focus (an area of enhancement < 5mm in diameter which is too small to characterize)
- Typically stable on follow-up, considered to be a part of the normal background enhancement pattern in the breast
4. ↑ T2 fat sat (Water content): Cyst, lymph node, fibroadenoma, fat necrosis, colloid carcinoma
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6. Kinetics:
Type 1 Slow initial rise, then continue rise with time 6% malignant
Type 2 Slow / rapid initial rise, then plateau in delayed phase Btw 6% (type 1) & 29-77% (type 3)
Type 3 Rapid initial rise, then drop-off (washout) in delayed phase 29-77% malignant
C. Non mass-like enhancement (an area of enhancement without a detectable 3-dimensional mass)
1. Distribution
a) Focal / punctate Enhancement < 25% of a breast quadrant 25% malignant
b) Linear Linear enhancement but not in ductal orientation 31% malignant
c) Ductal Enhancement in ductal distribution 60% malignant
d) Segmental Multiple ductal enhancement 78% malignant
e) Regional Non- ductal or segmental enhancement, but larger than focal 21% malignant
f) Diffuse Diffuse enhancement Typically benign
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D. Ductography
Indications Investigation for single duct discharge, TRO intraluminal abnormality (eg Papilloma)
Equipment 1. Jabzenski cannula
2. LOCM
Technique - Insert Jabzenski cannula (prefilled wt CM), through a duct orifice on nipple surface
- Inject CM
- Acquire x-ray image
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F. Lymphoscintigraphy of Breast
Indications Indication: Contraindication:
For sentinel node mapping 1. Allergy to human albumin products
→ If sentinel node is –ve 2. Complete blockage of lymphatic system
→ Extensive axillary LN clearance can be avoided
Radiopharma 99mTc-colloidal
albumin
May complement with Methylene blue dye (visible to naked eye)
Preparation None
Aftercare None
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Equipment Automated biopsy gun (Bard biopsy system) + Biopsy needle 14-16G
Technique - Approaches:
a) Ultrasound guided Linear transducer 8-18 MHz
b) Mammographic guided Imaging of a static object, from 2 known angles, from a known zero point
(Stereotactic technique) → Calculation of X, Y, Z coordinates
- Clean & drape, LA infiltrated
- Insert biopsy needle 14-16G (via automated biopsy gun), under mammo / US guidance
- Obtain ≥ 3 passes of specimen
Aftercare 1. Observe for bleeding / haematoma, may require compression / cold pack
2. Analgesia
3. Avoid heavy lifting on the biopsied side
Technique - Approaches:
a) Ultrasound guided Linear transducer 8-18 MHz
b) Mammographic guided Imaging of a static object, from 2 known angles, from a known zero point
(Stereotactic technique) → Calculation of X, Y, Z coordinates
- Clean & drape, LA infiltrated
- Insert localizing (Hook) wire, till its tip within the lesion, under mammo / US guidance
- After wire placement, acquire mammographic / US images, to indicate the position of the tip
- Mark the skin immediately overlying the lesion, measure the depth of target
- Secure the wire on the skin
Aftercare 1. Observe for bleeding / haematoma, may require compression / cold pack
2. Analgesia
3. Avoid heavy lifting / vigorous movement on the biopsied side
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GENERAL PRINCIPLES
Contrast Media
Dilution of Barium sulphate:
Examination Dilution (% w/v) Ingredients
a) Barium swallow 150 600g BaSO4 + 400mls water
b) Barium meal 240 600g BaSO4 + 250mls water
c) Barium follow-through 60 600g BaSO4 + 1L water
d) Small bowel enema 20 300g BaSO4 + 1.5L water
e) Barium enema 60 600g BaSO4 + 1L water
f) Defecating proctogram 60 Oral: 600g BaSO4 + 1L water (Drink 600mls)
Rectal: Remaining 400mls + 100g BaSO4 + 50g potato
Paediatrics
Examination Dilution (% w/v) Ingredients
a) Upper GI study 20 300g BaSO4 + 1.5L water
b) Lower GI study 60 600g BaSO4 + 1L water
(single contrast Ba enema)
Bowel Preparation
3 days before examination Low residual diet
2 days before examination T. Bisacodyl (Dulcolax) 10mg ON x 2 days
1 day before examination - Light breakfast, then only clear fluids
- Drink lots of clear fluids subsequently
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GASTRO-INTESTINAL TRACT
A. Barium Swallow
Indications Indications: Contraindications:
1. Dysphagia & odynophagia 1. No absolute
2. Unexplained anemia 2. CIx for contrast media & ionizing radiation
3. Tracheo-oesophageal fistula (Barium / LOCM)
4. Assess the site of perforation (water soluble CM)
Contrast 1. BaSO4 (E-Z HD): 225% w/v
2. Gastrograffin→ If suspect perforation
3. LOCM (Ultravist, omnipaque, iopamero) → If patient at risk of aspiration, trachea-oesophageal fistula
Preparation None, unless combine wt barium meal
Technique - Erect position
- Swallow ample mouthful of barium, followed by gas (for double contrast study), spot films taken
Position Projections Frames/sec
a) Laryngopharynx & upper oesophagus PA & lateral 4
b) Mid oesophagus RAO, to throw the oesophagus of spine 2
c) Lower oesophagus & GE junction PA (for GE junction) & RAO 2
Oesophagealvarices Prone RPO, to distend the varices
- Images taken for all projections must be:
a) Full column Single contrast: Barium-filled
b) Air column Double contrast: Mucosal coating wt barium
c) Air collapse
Important indentations:
a) Cervical region b) Thoracic region
- Anterior indentations: Posterior cricoid venous plexus - Aortic arch
- Posterior indentations: Crico-pharyngeus - Left main bronchus
- Left atrium
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Hypopharynx (AP)
1. Pharynx
2. Lateral glosso-epiglottic fold
3. Vallecula
4. Epiglottis
5. Piriform recess
6. Esophagus
Hypopharynx (Lateral)
1. Uvula
2. C2
3. Tongue
4. Oropharynx
5. Mandible
6. Vallecula
7. Larynx
8. Hyoid bone
9. Piriform recess
10. Larynx – Ventricle
11. Esophagus
12. Trachea
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1. Distal esophagus
2. Gastro-esophageal angle
3. Abdominal esophagus
4. Esophageal hiatus
5. Cardia
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B. Barium Meal
Indications 1. Double contrast study: 2. Single contrast study:
To demonstrate mucosal pattern (method of choice) To demonstrate gross pathology (for paeds)
To determine the cause of vomiting in paeds
a) Failed OGDS
b) Dyspepsia, reflux Sx a) Malrotation
c) Upper abdominal mass b) Duodenal stenosis / atresia
d) Partial obstruction c) Pyloric obstruction (only if US inconclusive)
e) Unexplained anemia d) Gastro-oesophageal reflux
f) Weight loss
g) Assess the site of perforation (water soluble CM)
CIx 1. Complete large bowel obstruction
2. CIx for contrast media & ionizing radiation
Contrast 1. Double contrast study: 2. Single contrast study:
a) BaSO4 (E-Z HD): 240% w/v a) BaSO4 (E-Z HD): 30% w/v
b) Effervescent (Carbex) granules No paralytic agent used
→ Produce CO2 for better coating
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1. Fundus 8. Pylorus
2. Abdominal esophagus 9. Stomach body
3. Cardia 10. Angular notch
4. Lesser curvature 11. Greater curvature
5. Duodenum 12. Pyloric antrum
6. Ampulla of Vater 13. Antrum
7. Gastric folds (posterior wall)
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C. Barium Follow-through
Indications Indications: (= Small bowel enema) Contraindications: (= Small bowel enema)
1. Pain 1. Complete bowel obstruction
2. Diarrhoea 2. Suspected perforation
3. Malabsorption 3. CIx for contrast media & ionizing radiation
4. Abdominal mass
5. Partial obstruction
6. Unexplained anemia
Aftercare 1. Bowel motions will be white for few days (may require 2wks for satisfactory clearance of barium)
(= Ba meal) 2. Eat & drink normally to avoid barium impaction
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1. Jejunum
2. Junction of ileum & jejunum
3. Ileum
4. Caecum
5. Appendix
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Complication 1. Aspiration
2. Perforation, d/t manipulation of guidewire
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E. Barium Enema
Indications Indications: Contraindications:
Large bowel pathology 1. Toxic megacolon
2. Pseudomembranous colitis
a) Double contrast study 3. Recent rectal biopsy
To demonstrate mucosal pattern (method of choice) a) Rigid endoscope: Within 5 days
b) Single contrast study b) Flexible endoscope: Within 1 day
To demonstrate gross pathology (for paeds) 4. CIx for contrast media & ionizing radiation
Reduction of intussusception (obsolete) Suboptimal study if:
1. Incomplete bowel preparation
2. Recent barium meal
3. Patient frailty
Contrast 1. BaSO4 (Polibar): 60% w/v
2. Air
Preparation Bowel preparation
Catheter Miller enema tube
Technique - Prelim: Plain AXR, TRO perforation & toxic megacolon, to assess bowel preparation
- Left lateral position
- Miller enema tube inserted into rectum, taped firmly in position
Connected to barium bag
- IV Buscopan 20mg / Glucagon 1mg given
- Barium is infused, intermittent screening to check progression, till barium reaches hepatic flexure
- Barium is run back out, by lowering the infusion bag to the floor
- Air is pumped in, forcing barium towards caecum, producing double contrast effect
- Spot films taken:
a) Rectosigmoid colon Lying: RAO, prone, LPO, left lateral
b) Rectum Erect: Left lateral
c) Splenic flexure Erect: LAO
d) Hepatic flexure Erect: RAO
e) Caecal pole Lying: LAO
- Overcouch films taken:
a) Supine
b) Prone
c) Left lateral decubitus
d) Right lateral decubitus
e) Hampton’s view (to visualize sigmoid colon): Prone, tube angled 45o caudally, centered at 5cm above PSIS
Aftercare 1. Bowel motions will be white for few days (may require 2wks for satisfactory clearance of barium)
2. Eat & drink normally to avoid barium impaction
Complication 1. Constipation & impaction 5. Cardiac arrhythmia, d/t rectal distension
2. Bowel perforation 6. Venous intravasation → May cause barium pulmonary embolism (Mortality rate 80%)
3. Intramural barium 7. Side-effects of pharmacological agents used
4. Transient bacteremia
AP – Supine AP – Prone
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1. Splenic flexure
2. Hepatic flexure
3. Ascending colon
4. Transverse colon
5. Descending colon
6. Haustra
7. Ileocaecal valve
8. Caecum
9. Sigmoid colon
10. Appendix
11. Rectum
1. Rectosigmoid junction
2. Sacrum
3. Retrorectal space
4. Transverse rectal fold
5. Femoral head
6. Rectal ampulla
7. Coccyx
8. Anorectal junction
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Instant Enema
Indications Indications: Contraindications:
1. To identify level of suspected large bowel obstruction 1. Toxic megacolon
2. To show the extent of mucosal lesions in active 2. Recent rectal biopsy
ulcerative colitis a) Rigid endoscope: Within 5 days
b) Flexible endoscope: Within 1 day
3. Chronic ulcerative colitis (formal Ba enema should be done)
4. Crohn’s colitis (unreliable assessment)
5. CIx for contrast media & ionizing radiation
Air Enema
Indications To show the extent of ulcerative colitis
Contrast Air
Technique - Insert Foley catheter (14 – 16 Fr) into rectum, inflate balloon (10 – 20 mls)
- Overcouch prelim film taken: AP Abdomen
- IV Buscopan 20mg / Glucagon 1mg given
- Pump air into catheter lumen
- Overcouch film taken: AP Abdomen
F. Herniography
Indications Indications: Contraindications:
1. History suggestive of hernia 1. Pregnancy
But inconclusive physical examination 2. Infant
2. Undiagnosed groin pain 3. Intestinal obstruction
4. CIx for contrast media & ionizing radiation
Aftercare None
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G. Defecating Proctogram
Indications Indications: Contraindications:
1. Constipation 1. Pregnancy
2. Pelvic floor weakness 2. CIx for contrast media & ionizing radiation
(rectocoele, enterocoele, rectal intussusception)
3. Anorectal incontinence (manometry / anal US preferred)
Technique - Drink 600mls of diluted barium 30mins before examination, to opacify the small bowel
- Left lateral position
Insert Foley catheter into rectum
Barium paste (150 – 200 mls) syringed into rectum
Screen to confirm that barium paste has reached the level of sacral promontory
- Patient sit on commode, in lateral projection
- Video recording / spot films taken, during:
a) Rest
b) Valsalva manoeuvre
c) Pelvic floor contractions
Aftercare 1. Bowel motions will be white for few days (may require 2wks for satisfactory clearance of barium)
2. Eat & drink normally to avoid barium impaction
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2. Colostomy Enema
Indications Indications: Contraindications:
To demonstrate anatomy of large bowel, 1. No absolute, perforation
proximal to colostomy 2. CIx for contrast media & ionizing radiation
Contrast 1. BaSO4 (Polibar): 60% w/v
2. Air
Preparation Bowel preparation
Technique - Insert Foley catheter (22 – 26Fr) into colostomy, inflate balloon (10 – 20 mls) at the lip of colostomy
Connected to barium bag
- IV Buscopan 20mg / Glucagon 1mg given
- Barium is infused as in barium enema
Aftercare = Barium enema
Complication Perforation
= Barium enema
3. Distal Loopogram
Indications Indications: Contraindications:
To demonstrate anatomy of bowel, distal to stoma 1. No absolute, perforation
(usually before reversal of Hartmann) 2. CIx for contrast media & ionizing radiation
Contrast Water soluble CM (Gastrograffin or LOCM)
Preparation None
Technique - Insert Foley catheter into stoma, inflate balloon (10 – 20 mls) at the lip of stoma
- Inject contrast into bowel
- Spot films taken
Aftercare None
Complication Perforation
4. Conduitogram
Indications Indications: Contraindications:
To demonstrate anatomy of ileal conduit, ureters & renal 1. No absolute, perforation
pelvicalyceal systems 2. CIx for contrast media & ionizing radiation
1. Narrowing / obstruction of ileal conduit
2. Narrowing / obstruction at anastomosis
3. Leaking
Contrast Water soluble CM (Gastrograffin or LOCM)
Preparation None
Technique - Insert Foley catheter (18 – 20Fr) into stoma, inflate balloon (10 – 20 mls) at the lip of stoma
- Inject contrast into ileal conduit
- Spot films taken
Aftercare None
Complication Perforation
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I. PAEDIATRICS
1. Upper GI study: Contrast Swallow
Indications Indications: Contraindications:
Tracheo-oesophageal fistula (Barium / LOCM) 1. No absolute, suspected perforation
2. CIx for contrast media & ionizing radiation
Aftercare 1. Bowel motions will be white for few days (may require 2wks for satisfactory clearance of barium)
2. Eat & drink normally to avoid barium impaction
Aftercare 1. Bowel motions will be white for few days (may require 2wks for satisfactory clearance of barium)
2. Eat & drink normally to avoid barium impaction
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Contrast Gastrograffin-150
- Do not provoke large fluid shifts
- Less complication if bowel perforated
- Provide satisfactory images
- Can be therapeutic for meconium ileus
4. Reduction of Intussusception
Indications Indications: Contraindications:
1. Intussusception 1. Perforation
2. Peritonitis
Contrast 1. Air & fluoroscopy (Pneumatic reduction) → Less suitable for >4yrs, may miss lead points
2. NS & ultrasound (Saline reduction)
Barium reduction is not practiced d/t complications
Complication Perforation
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Correct position UAC: Tip at aortic arch UAC: Tip at Lf common iliac UAC: Folded in aorta
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GENITO-URINARY TRACT
A. Intravenous Urography, IVU (Excretion urography)
Indications Indications: Contraindications:
1. Haematuria 1. No absolute
2. Renal colic 2. CIx for contrast media & ionizing radiation
3. Recurrent UTI (congenital abN, strictures)
4. Suspected urinary tract pathology (tumour)
Contrast LOCM-300
- Adult dose: 50 – 100ml
- Paeds dose: 1 ml/kg
Preparation Before examination:
1. NBM 4-6 hrs. Dehydration is not necessary to improve image quality
2. Bowel prep is not necessary to improve image quality
3. Ambulation 2hrs prior to examination, to ↓ bowel gas
During examination:
1. IV line, antecubital vein (as flow is ↓ in cephalic vein as it pierces clavipectoral fascia)
Technique 1. Preliminary film
a) Supine AP abdomen, in inspiration b) Additional
- Lower border: Symphysis pubis (i) Supine AP renal areas, in expiration
- CR: Midline, level of iliac crest (ii) 35o posterior oblique views
(iii) Tomography of kidneys at the level of ⅓ AP diameter of patient (≈ 10cm)
Injection of contrast media
2. Immediate film (Nephrogram)
- AP renal areas
- Time: 10 – 14secs after injection (arm-to-kidney time)
- Image: Renal parenchymal (renal tubules) opacified by contrast media
- Usually omitted
May need extra contrast media if there is poor initial opacification
3. 5-min film (Excretory / Pyelogram)
- AP renal areas
- Aim: To assess for symmetrical excretion & hydronephrosis
Distension of pelvicalyceal system:
a) Compression
- Compression band applied ard abdomen
- Balloon at midway btw ASIS (ureters as they cross the pelvic brim)
- Contraindication for compression:
(i) Paediatric patients
(ii) When 5-min film shows well-distended calyces or hydronephrosis
(iii) Abdominal pain / ureteric colic
(iv) Large abdominal mass, aortic aneurysm
(v) Recent abdominal surgery
(vi) Recent renal trauma
(vii) Renal transplant
b) Head down position
c) Prone position (PA abdomen)
4. 10-min film (Compression)
- AP renal areas
- Aim: To show the well-distended pelvicalyceal systems
Release of compression if distension if satisfactory
5. Release film
- Supine AP abdomen
- Aim: To show the whole urinary tract
Empty the bladder
6. Post-micturition film
- Supine AP abdomen OR
Coned view of bladder, 15o caudal angulation, center 5cm above symphysis pubis (Cystogram)
- Aim: To assess bladder emptying & return of the dilated upper tracts to normal
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Additional films:
- 35o posterior obliques of KUB
- 30o caudal angulation of renal areas (to clear the transverse colon from kidneys)
- Tomography (if there are confusing overlying shadows)
Complication 1. Upper arm / shoulder pain d/t stasis of contrast media
- Treatment: Abduction of the arm
2. General complications of CM
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D. Hysterosalpingography, HSG
Indications Indications: Contraindications:
1. Infertility 1. During menses
2. Recurrent miscarriage (incompetent cervix, congenital abN) 2. Pregnancy
3. Post-sterilization, to confirm obstruction / patency 3. Active pelvic infection (purulent discharge)
before reversal of sterilization PID in preceding 6mths
4. Assess integrity of caesarean uterine scar 4. CIx for contrast media & ionizing radiation
Equipment 1. Vaginal speculum: Cusco bivalve speculum
2. Vulsellum forceps
3. Cannulation:
a) Foley catheter 8Fr
b) Leech-Wilkinson catheter
c) HSG balloon catheter 5Fr or 7Fr
Contrast LOCM-300, 10-20 mls
Preparation HSG usually performed on D10-12 menses (or 2days after bleeding stops), risk of contrast intravasation after D12
Abstain from intercourse, from D1 menses till day of examination
NBM for 6hrs, not necessarily, but practiced in HUKM in fear of contrast intravasation
Technique - Prelim: Coned PA view of pelvis
- Lithotomy position
- Clean & drape
- Insert vaginal speculum, inspect & clean the vagina & cervix
- Prefill the catheter wt CM (to expel air bubbles)
Insert catheter into cervical canal, inflate balloon wt 1-2 mls water (Foley catheter)
Remove instrumentation
- Patient change to supine position, without lifting the back from couch
- Inject CM, screening & spot films taken
a) During filling of uterus - PA
- Early, mid & full
b) During filling of tubes - PA
- Isthmus & ampullary phases
c) Peritoneal spillage - PA
- May need to change to oblique position,
to avoid contamination of CM from the side of spillage
d) Cervical canal - PA
- During removal of catheter
- IV / IM Buscopan or Glucagon may be required to relieve spasm (Opioids can cause spasm)
Aftercare 1. PV bleed for 1-2 days
2. Lower abdominal pain up to 2wks
Complication 1. Pain, due to Predisposing Fc of contrast intravasation:
a) Using vulsellum forceps 1. Timing of procedure near menstruation
b) Insertion of catheter 2. Timing of procedure following curettage
c) Uterine distension 3. Uterine anomalies (uterine ca, infection, fibroid)
d) Tubal distension, proximal to a block 4. Direct trauma to endometrium
e) Peritoneal irritation following spillage of CM, up to 2wks 5. Tubal occlusion causing high pressure
2. Bleeding
3. Transient nausea, vomiting, headache
4. Infection
5. Venous intravasation of CM → Lace-liked pattern within uterine wall
6. Allergic reaction, d/t intravasation of CM
7. Abortion
1. Uterine fundus
2. Ostium of fallopian tube
3. Fallopian tube
4. Uterine cavity
5. Cervical canal
6. Fimbriae
7. Vagina
8. Catheter
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E. Genitography
Indications Indications: Contraindications:
Ambiguous external genitalia 1. CIx for contrast media & ionizing radiation
Contrast LOCM-300, 3-4 mls
Preparation None
Technique - Supine position
- Clean & drape
- Examine perineal area, to determine presence of
a) Single wide cloanal opening
b) More than one orifice
- CM injection:
a) Single wide cloanal opening - Insert a soft rubber acorn (prefilled wt contrast) to the opening
- Inject CM 3-4 mls, while screening
b) More than one orifice Perform as in cystography
- Acquire images (from screening, no spot films): AP & lateral views
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B. Sialography
Indications Indications: Contraindications:
1. Symptoms: Pain, swelling 1. Acute infection / inflammation
2. Sialolithiasis, sialadenitis, tumour, metastasis, Sicca (Sjogren) syndrome 2. CIx for contrast media & ionizing radiation
Equipment 1. Digital subtraction angiographic unit
2. Silver dilator & cannula -OR- Blunt needle 18G wt polythene catheter
Contrast LOCM-300: Dilution 50%, up to 2mls
Technique - Remove dentures / any radio-opaque artifacts
- Prelim film:
1. Parotid gland (Stensen) 2. Submandibular gland (Wharton)
a) AP - Head rotated 5o away from site of interest a) Infero- Useful view to show calculi
- Center at midline of lower lip superior
b) Lateral Center at angle of mandible b) Lateral Wt floor of the mouth depressed by a
wooden spatula
c) Lateral - Center at angle of mandible c) Lateral - Center 1cm ant to angle of mandible
oblique - Wt tube angled 20o cephalic oblique - Wt tube angled 20o cephalic
- Apply sialogogue (eg. citric acid, lemon, lime) in the mouth, to promote gland secretion & render the orifice visible
- Locate the orifice of the salivary gland
a) Parotid gland Adjacent to the crown of 2nd upper molar
b) Submandibular gland At the base of frenulum of the tongue
- Dilate the orifice wt silver dilator / blunt needle 18G, insert the cannula / polythene catheter into the duct
- Inject CM (up to 2 mls), stop the injection if there is pain (DO NOT overfill the duct)
- Acquire digital subtraction images
a) Immediate films - Immediately after injection of CM
- Same views as prelim films
b) Delayed (post-secretory) films - 5mins after injection of CM
- Same views as prelim films
- Can examine the duct bilaterally, simultaneously
But not separately, as opacification of 1st duct, will superimpose on the later examined contralateral duct
Complication 1. Pain
2. Damage to the orifice / Perforation of the ducts
3. Infection
Parotid: AP Lateral Lateral oblique
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SPINE
A. Myelography
Indications Indications: Contraindications:
Patient is contraindicated / unwilling to undergo MRI 1. Raised ICP
1. Spinal cord pathology 2. Local sepsis
- Spinal stenosis 3. Distorted bony anatomy at puncture site
- Conus medullary syndrome - Severe scoliosis, severe spondysosis, RA
2. Exiting / traversing nerve root pathology - Cervical puncture: Cranio / cervical pathology
- Lumbar puncture: Recent LP
- Nerve root compression
- Cauda-equina compression 4. CIx for contrast media & ionizing radiation
- Prone position
Neck in neutral / slight extension
- Clean & drape, LA infiltrated
- Identify puncture site under fluoro guidance (lateral beam): C1/C2 intervertebral space, midline
- Insert spinal needle 20G, at puncture site
- Advance it parallel to long axis of spine, till it enters subarachnoid space:
Btw laminae of C1 & C2, at junction btw middle & posterior ⅓ of spinal canal
If the needle is too far anterior → in contact wt exiting nerve root → Neck / radicular pain
- Remove stilette, observe for free flow of CSF
- Test injection of small volume of CM, to confirm position under fluoro
CM will flow anteriorly away from needle tip, to layer behind vertebral bodies
- Inject required volume of CM
- May need to tilt the table, to ensure CM flow into upper cervical & thoracic spinal canal
- Remove needle
- Spot films taken (cervical myelography):
a) AP with cranial & caudal angulation
b) Rt oblique & Lt oblique with cranial & caudal angulation
c) Lateral view (i) with soft & penetrated views (for full assessment of cervico-thoracic junction)
(ii) wt mild neck flexion (for full visualization of upper cervical cord to foramen magnum)
- Proceed wt CT myelography after 4hrs, to allow CM dilution
Lumbar puncture:
General principles:
- Approach of choice
- Safer, less complications
- Suitable for lumbar / thoracic / cervical / whole spine studies, unless presence of spinal stenosis which restrict flow of CM
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- Position:
a) Lateral decubitus Preferred approach
b) Prone May be technically difficult, d/t approximation of spinous process
c) Sitting Injected CM will be diluted by CSF accumulated in sacral sac, as it descends
- Lateral decubitus wt moderate spinal flexion
Support the dependent lumbar angle wt a pillow, to keep the spine straight
- Clean & drape, LA infiltrated
- Identify puncture site wt manual palpation / fluoro guidance (lateral beam):
L2/L3, L3/L4, L5/S1 intervertebral space (1-2 spinous process above iliac crest), midline (unless canal stenosis)
- Insert spinal needle 22G, at puncture site
- Advance it wt 10-15o cranial angulation, till it enters subarachnoid space / thecal sac
(initial moderate smooth resistance, followed by sudden loss of resistance)
- Remove stilette, observe for free flow of CSF
- Inject required volume of CM (may test inject small volume of CM, to confirm position under fluoro)
- Remove needle
- Turn patient to prone position, spot films taken:
a) Lumbar myelography
(i) AP
(ii) Rt oblique & Lt oblique Usually 25o
(iii) Lateral view - Prone lateral
- Erect lateral, wt mild flexion & extension
(iv) Assessment of thoraco-lumbar - Lateral decubitus wt slight head down position
junction & lower thoracic region - Supine AP
b) Thoracic myelography
- Head-down position wt head supported on a pad (for CM to flow upwards, but not beyond foramen magnum)
- Inject ½ of CM & screen, look for spinal canal stenosis
- If no obstruction, inject the remaining CM
(i) AP
(ii) Rt oblique & Lt oblique
(iii) Lateral view
c) Cervical myelography
(i) AP with cranial & caudal angulation
(ii ) Rt oblique & Lt oblique with cranial & caudal angulation
(iii) Lateral view (i) with soft & penetrated views (for full assessment of cervico-thoracic junction)
(ii) wt mild neck flexion (for full visualization of upper cervical cord to foramen magnum)
- Proceed wt CT myelography after 4hrs, to allow CM dilution
Aftercare Brief observation
Complication 1. Nausea & vomiting (5%)
2. Headache (25%)
3. Arachnoiditis (Rarely happens wt currently used LOCM)
4. Damage to local structures: a) Cervical puncture: Vertebral artery damage
b) Cord puncture
5. Extra-thecal injection of CM
a) Extradural - Outlines the nerve roots beyond the exit foramina
b) Subdural - Happens when only the bevel of spinal needle is within subarachenoid space
- Need to repeat the test at a later date
c) Intramedullary - Slit-like collection of CM within spinal canal
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Cervical myelogram
Thoracic myelogram
AP Oblique Lateral
Lumbar myelogram
AP Lateral Oblique
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Lumbar discogram
B. Lumbar Discography
Indications Indications: Contraindications:
1. Discogenic pain without radicular signs 1. Local / distant sepsis(risk of infective discitis)
2. To confirm normal disc above/below a proposed 2. No plan for surgical intervention
surgical fusion 3. CIx for contrast media & ionizing radiation
Limited role in thoracic & cervical discogenic pain
Avoid (painful procedure with high risk of complications)
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A. Shoulder Arthrography
- Position: Supine
Arm of interest adducted & external rotated, palm facing up
- Identify & mark the injection site under fluoro guidance: 1cm inferior & 1cm lateral, to coracoid process
- Clean & drape
- Puncture injection site wt green needle (21G), infiltrate lignocaine 1%, exchange to syringe wt CM
- Advance needle into joint space, aiming for cortex of humeral head, till it reaches the bone
Right side Aim at 4 o’clock of femoral head
Left side Aim at 8 o’clock of femoral head
- Aspirate for synovial fluid
- Test injection of small volume of CM, to confirm position
- Inject full volume of CM
- Remove the needle, gently manipulate the joint to distribute the CM
- Acquire AP & lateral images
- Proceed wt conventional / CT / MRI, within 30mins after injection (as CM is being absorbed)
B. Elbow Arthrography
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C. Wrist Arthrography
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D. Hip Arthrography
- Position: Supine
Leg of interest extended & internal rotated
- Identify & mark the injection site under fluoro guidance: Midpoint of intertrochanteric line
- Clean & drape
- Puncture injection site wt spinal needle (20G), infiltrate lignocaine 1%, exchange to syringe wt CM
- Advance needle into joint space, vertical-supero-laterally,
till it reaches femoral neck, immediately below the junction of femoral head & neck laterally
- Aspirate for synovial fluid
- Test injection of small volume of CM, to confirm position
- Inject full volume of CM
- Remove the needle, gently manipulate the joint to distribute the CM
- Acquire images
Adult AP
Lateral
Paeds AP
Frog lateral
Abduction & internal rotation
Maximum abduction
Maximum adduction
Push / pull views to demonstrate instability
- Proceed wt conventional / CT / MRI, within 30mins after injection (as CM is being absorbed)
E. Knee Arthrography
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F. Ankle Arthrography
- Position: Lateral
Ankle of interest in plantar-flexion
- Identify & mark the injection site under fluoro guidance: Dorsal (anterior) surface, midpoint of 2 malleoli
- Clean & drape
- Puncture injection site wt green needle (21G), infiltrate lignocaine 1%, exchange to syringe wt CM
- Advance needle into anterior joint space
- Aspirate for synovial fluid
- Test injection of small volume of CM, to confirm position
- Inject full volume of CM
- Remove the needle, gently manipulate the joint to distribute the CM
- Acquire AP & lateral images
- Proceed wt conventional / CT / MRI, within 30mins after injection (as CM is being absorbed)
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- Types of guidewire:
Category Examples Guidewire Usage
a) Stiff Amplatz (Blue) Urology procedures
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3. Introducer sheath
- To facilitate the manipulation of catheters
- When frequent catheter exchanges is anticipated / required
4. Catheters
- Material: Polyurethane / polyethylene
- Consists of: End hole, side holes, performed curves, Luer lock connector (at the end)
- Types of catheter:
Flush catheters
a) Straight pigtail End holes: 1
Side holes: 10-12
- For arch aortogram
- During removal,
guidewire is inserted to
straighten catheter tip,
to ↓ risk of intimal damage
Cerebral catheters
a) Vertebral End holes: 1
Side holes: 0
c) JB 2 End holes: 1
Side holes: 0
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Femoral-Visceral catheters
a) Simmons (Sims) / End holes: 1
Sidewinder Side holes: 0
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Approach of puncture
1. Relative contraindications:
a) Bleeding tendency
b) Aneurysm / pseudo-aneurysm at puncture site
c) Severe atherosclerosis of artery proximal to punctured artery
d) Local soft tissue infection
e) Ehlers-Danlos syndrome (fragile vessel wall)
f) Severe HPT
2. Techniques of puncture
a) Seldinger technique - Both walls of vessel are punctured (through-and-through)
(Double-wall puncture) - Stilette removed
- Needle withdrawn till its tip within the lumen of vessel
↓ Risk of intimal dissection - Guidewire inserted through needle
- Needle removed
- Introducer sheath / catheter threaded over the guidewire
- Guidewire removed
b) Modified Seldinger technique - Single wall of vessel is punctured, needle tip (18G) within the lumen of vessel
(Single-wall puncture) - Guidewire (J-tip) inserted through needle
- Needle removed
↑ Risk of intimal dissection - Introducer sheath / catheter threaded over the guidewire
- Guidewire removed
3. Sites of puncture
a) Femoral artery - Supine position, clean & drape, LA infiltrated
- Usually right side is chosen (unless contraindicated or failed cannulation)
- Locate puncture site:
(i) Clinically - Locate pulsation of femoral artery, inferior to inguinal ligament
- Femoral art continues as ext iliac art superior to inguinal lig
Haemostasis may be difficult to secure by manual compression
(ii) Fluoro guidance - Locate middle ⅓ of femoral head
(iii) US guidance - Femoral art is lateral to femoral vein, pulsatile, non-compressible
- Make a small incision, puncture via Seldinger / modified Seldinger technique
- Obtain good pulsatile blood flow (to indicate satisfactory puncture)
Causes of poor flow: Femoral vein puncture, arterial stenosis, hypotension
- Insert guidewire through needle, intermittent screening to assess position
Femoral art puncture Femoral vein puncture
- Bright-coloured blood - Dark-coloured blood
- Good pulsatile blood flow - Non-pulsatile blood flow
- Guidewire on the left side (aorta) - Guidewire on the right side (IVC)
- CM flow towards periphery - CM flow towards the heart
- Opacification of art branches by CM - No opacification of branches seen
- Remove needle, when guidewire is within thoracic aorta
- Thread introducer sheath / catheter over the guidewire
- Remove guidewire, when catheter tip is at the desired site
- At the end of procedure, remove introducer sheath / catheter
- Manual compression at puncture site for 5-10 mins
b) Brachial artery ↑ Incidence of complications, avoid unless femoral approach is not possible
- Arm in supination
- Location of puncture:
(i) Locate pulsation of brachial artery
(ii) 10cm above elbow
c) Axillary artery ↑ Incidence of complications, avoid unless femoral/brachial approaches are not possible
- Arm in full abduction
- Location of puncture: Just distal to axillary fold
d) Radial artery
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Coeliac axis 1. Simmons (Sims) / Sidewinder Femoral art Coeliac axis (T12/L1)
2. Cobra
SMA 1. Simmons (Sims) / Sidewinder Femoral art SMA (L1)
2. Cobra
IMA 1. Simmons (Sims) / Sidewinder Femoral art IMA (L3)
2. Cobra
Renal artery 1. Simmons (Sims) / Sidewinder Femoral art Selective renal art (L1 / L2)
2. Cobra
Iliac artery Pigtail Femoral art
Lower limb artery 1. Pigtail Brachial / axillary / femoral art
2. Simmons (Sims) / Sidewinder (Retrograde vs antegrade)
Cerebral angio 12
CCA 12 6 300 2 (VFR)
ICA 10 5 300 2 (VFR)
ECA 4 2 300 2 (VFR)
Vertebral artery 6 3 300 2 (VFR)
Spinal artery 14 6 300 2 (VFR)
Cardiac angio 40 20
Coronary angio 10 Hand inject
Pulmonary angio 40 20
Coeliac axis 36 6
SMA 42 7 600 6
IMA 10 4 or hand inject
Renal artery 10 5 300 2 (VFR)
Iliac artery 20 10 600 6
Lower limb artery
a) 1 limb 20 5
b) 2 limbs 50 15
Roadmap 10 5 300 -
3D Rotational 18 2.5 300 -
XPER CT 22 1 300 -
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Aftercare
1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complications
1. General complications of CM
2. Infections
a) Infection at puncture site
b) Bacteraemia / Sepsis
4. Haemorrhage / haematoma
- Incidence:
Small haematomas 20%
Large haematomas 4%
Haematoma requiring transfusion / surgery 0.5%
- Risk factors (↑ by):
a) Femoral artery puncture
b) Large catheters
c) Frequent catheter exchanges
d) Use of heparin / anti-thrombolytic agent / antiplatelet
e) Inadequate manual compression on puncture site
5. Pseudo-aneurysm (0.2%)
- Causes: Communication btw arterial lumen, wt a cavity bounded by haematoma
- Risk ↑ by: Puncture below bifurcation of common femoral artery
7. Arterial dissection
- Causes: Entry of puncture needle / guidewire / catheter / CM, into subintimal space
- Risk factors (↑ by):
a) Puncture needle / technique - Employ Seldinger technique (Double-wall puncture)
- Avoid using single-wall needle wt long bevel
b) Guidewire - Ensure the flexible end of guidewire is entered 1st, not the other end
c) Catheters - Use catheter wt multiple side holes
- Gentle manipulation of catheters
- Always insert guidewire to straighten the pigtail catheter tip, before removal
d) CM - Small volume of manual test injection of CM, before pump injection
8. Arterial thrombus
- Causes:
a) Stripping of thrombus from catheter wall
b) Thrombus formation following trauma to vessel wall
- Risk factors:
↑ by: ↓ by:
a) Guidewires wt additional Teflon coating a) Heparin-bonded guidewires
b) Polyurethane catheters (rough surface) b) Heparin-bonded catheters
c) Large catheters c) Flushing wt heparinized saline
d) Frequent catheter exchanges
e) Prolonged procedure
f) Inexperience radiologist
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9. Embolism
a) Peripheral embolism (0.5%)
- Causes:
(i) Stripping of thrombus from catheter wall
(ii) Stripping of thrombus formed following trauma to vessel wall
(iii) Dislodged atheromatous plaques
- Sequelae:
(i) Emboli to small artery → Resolve spontaneously
(ii) Emboli to large artery → May need catheter aspiration thrombectomy / surgical embolectomy
b) Air embolism
- Causes: Improper handling of instruments
- May be fatal in coronary / cerebral arteries
- Risk factors (↓ by):
(i) Ensure all connectors are tight
(ii) Always suck back when syringe is connected to catheter
(iii) Ensure air bubbles are expelled from syringe, before injection
(iv) Keep the syringe vertical, when injecting
c) Cotton fibre embolism
- Causes:
(i) Syringe are filled from a gauze pad
(ii) Guidewire is wiped wt dry gauze
- Risk factors ↓ by: Separate bowls of saline for flushing & wet gauze
10. Instrumental-related
a) Guidewire breakage
- Usually involve the 5cm from the tip (flexible end)
b) Catheter knotting
- More likely during angiography of complex congenital heart disease
- Treatment:
(i) Non-surgical reduction of catheter knots
(ii) Surgical removal
c) Catheter impaction
- Signs of catheter impaction:
(i) Sound of sucking air upon removal of guidewire
(ii) Poor back-bleeding from catheter
(iii) Rapid wash-out of CM after a selective injection
- Sequelae: Ischaemic pain (esp. coronary & mesenteric arteries)
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CARDIOVASCULAR SYSTEM
HEART
A. Cardiac Angiography / Angiocardiography
Indications Indications: Contraindications:
1. Congenital heart disease (ASD, VSD, PDA) 1. No absolute, bleeding tendency
prior to therapeutic procedures (transcatheter closure) 2. CIx for IV contrast media & ionizing radiation
2. Congenital anomalies of great vessels
prior to therapeutic procedures
3. Myocardial disease
4. Valvular heart disease
prior to therapeutic procedures (balloon valvuloplasty)
5. Assessment of ventricular function
Diagnostic angiocardiography has been replaced by
echo, CT, MRI & radionuclide ventriculography
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter:
a) For pressure measurement: Cournand catheer
b) For angiocardiography: Pigtail / NIH catheter
Contrast LOCM-370: 40 mls, 20 mls/sec
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique):
a) Rt heart structures & pulm art Femoral vein / Rt antecubital vein / Rt basilic vein
(Avoid cephalic vein d/t difficult passage at clavi-pectorial fascia)
b) Lt heart structures & aorta Adult: Femoral artery
Paeds: Femoral vein → Patent foramen ovale → Lt heart
- Place tip of catheter into appropriate positions & perform angiographic runs
Contrast: 30-40 mls, 15-20 mls/sec
- Image acquisition at 30 frames/sec
a) 4-chamber / Hepatoclavicular / - Lateral beam ∟ long axis of the heart
40o-cranial 40o-LAO view - Lateral beam angled 40o cranially
to ║ line connecting atrial septum & post ventricular septum
b) Long axial oblique / - Lateral beam ∟ long axis of the heart
Long axial 20o -RAO view - Lateral beam angled 20o cranially
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B. Coronary Arteriography
Indications Indications: Contraindications:
1. IHD 1. No absolute, bleeding tendency
2. Congenital heart disease, prior to surgery 2. CIx for IV contrast media & ionizing radiation
3. Valvular heart disease, prior to surgery
4. After revascularization procedure
5. Therapeutic percutaneous coronary intervention
(Balloon angioplasty & stenting)
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter: Judkins / Amplatz coronary artery catheter
Contrast LOCM-370: 8-10 mls, hand inject for each projection
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Radial / brachial / femoral artery
- Place tip of catheter at tip of ostium of coronary art & perform angiographic runs
Contrast: 8-10 mls, hand inject
- Image acquisition at 30 frames/sec
a) RCA 30o RAO, 45oLAO, 45oLAO / 20o cranial
b) LCA 30o RAO, 10o RAO, 60oLAO, 4-chamber view
- Remove sheath, compression
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. Arrhythmias
2. Ostial dissection by catheter
3. General complications of CM
4. General complications of angiography
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ARTERIAL SYSTEM
C. Arch / Ascending Aortography
Indications Indications: Contraindications:
1. Preliminary to endovascular intervention 1. No absolute, bleeding tendency
2. Aortic lesions (aneurysm, dissection, trauma) 2. CIx for IV contrast media & ionizing radiation
3. Lesions of the major vessels (atheroma)
4. Aortic regurgitation
5. Congenital heart disease (coarctation of aorta)
Diagnostic aortography has been replaced by
echocardiography, CT & MRI
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter: Pigtail / Gensini / NIH
Contrast LOCM-370: 40mls, 20 mls/sec
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral artery
- Place tip of catheter at 1-3 cm above aortic valve
- Small volume of manual test injection of CM, before pump injection (to ensure catheter tip is not in coronary art)
- Perform angiographic (digital subtraction) runs
Contrast: 30-40 mls, 15-20 mls/sec
- Image acquisition at 20-30 frames/sec, PA & RPO view (to open out aortic arch)
- Remove sheath, compression
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. General complications of CM
2. General complications of angiography
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Left subclavian arteriogram Left axillary arteriogram Left brachial arteriogram Left radial / ulnar arteriogram
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G. Vascular Embolization
Indications Indications: Contraindications:
1.To control bleeding 1. No absolute
2. To ↓ / stop blood flow to AVM /aneurysm / fistulae 2. CIx for IV contrast media & ionizing radiation
3. To ↓ / stop blood flow to mass / organs
(tumour embo, uterine fibroid embo, treat priapism)
Equipment 1. Digital fluoroscopy wt angiography facility (preferably with road-map function)
2. Pump injector
3. Catheter: Should not have side holes which may promote clumping of particles, causing blockage
4. Embolic material:
a) Liquid Alcohol, squid, quick-setting glues, polymer
b) Particulate Gel-foam, polyvinyl alcohol, autologous clot
c) Solid Coils, detachable balloons
* All of above materials are permanent, except gel-foam & autologous clot
Contrast LOCM-370
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Selective catheterization of lesion
- Inject embolic material slowly & intermittently, to prevent reflux of embolic material
Aftercare 1. Observe tissue distal to occluded vessel, for ischaemia
2. Bed rest for 4-6hrs (femoral art puncture)
3. Monitor puncture site for bleeding / haemorrhage
4. Monitor vital signs
Complication 1. Misplacement of emboli
2. Propagation of thrombosis
3. Post-embolization syndrome, d/t toxins released by infarcted tissue → Fever, pain, ↑ WBC
4. General complications of CM
5. General complications of angiography
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VENOUS SYSTEM
H. Central Venography: Inferior Vena Cavography
Indications Indications: Contraindications:
1. Preliminary to transvenous intervention (IVC filter) 1. No absolute, bleeding tendency
2. IVC stenosis / occlusion / infiltration 2. CIx for IV contrast media & ionizing radiation
3. Congenital abN of venous system (Double IVC)
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter
Contrast LOCM-370: 30-40 mls, 15-20 mls/sec
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral vein (preferably under US guidance)
- Place tip of catheter at proximal to IVC bifurcation & perform angiographic (digital subtraction) runs
Contrast: 30-40 mls, 15-20 mls/sec
- Image acquisition at 2 frames/sec, PA & RPO view (to open out aortic arch)
- Remove catheter / sheath, compression
Aftercare 1. Pressure at venopuncture site
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. General complications of CM
2. General complications of angiography
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L. Dialysis Fistulography
Indications Indications: Contraindications:
Fistulous stenosis / occlusion 1. No absolute
2. CIx for IV contrast media & ionizing radiation
Equipment Digital fluoroscopy wt angiography facility
Contrast LOCM-300 (May dilute to 70%)
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, aseptic technique
- Apply tourniquet onto the examined arm
- Insert branulla 20G into the venous limb of the fistula / graft, wt its tip pointing towards the loop
- Tighten the tourniquet
- Hand inject CM into the fistula & perform a digital subtraction angiographic run
- May proceed wt fistuloplasty if indicated
Aftercare 1. Monitor puncture site for bleeding / haemorrhage
2. Monitor vital signs
Complication General complications of CM
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RESPIRATORY SYSTEM
A. Pulmonary Arteriography
Indications Indications: Contraindications:
1.Pulm embolism & other peripheral abN(AVM), 1. ↑Rt ventricle end-diastolic pressure (> 20mmHg) &
when CTPA is inconclusive ↑Pulm art pressure (> 70mmHg)
2. Pulm embolism, - ↑ Mortality rate to 2-3 %
prior to catheter-directed thrombolysis / embolectomy - Proceed wt selective pulm arteriography if needed
2. Left bundle branch block
Diagnostic pulmonary arteriogram has been replaced - Rt heart catheterization may induce complete heart block
by CTPA 3. Bleeding tendency
4. CIx for IV contrast media & ionizing radiation
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter: Pigtail / NIH catheter
Contrast IV LOCM-370: 30-40 mls, 15-20 mls/sec
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Right femoral vein
Other options (in the presence of ileo-femoral thrombus): Jugular vein, basilic vein
- Cannulate artery (pigtail / NIH catheter) & perform angiographic (digital subtraction) runs:
Contrast: 30-40 mls, 15-20 mls/sec
a) Pulm arteriogram - Place tip of catheter 1-3 cm above pulm valve
- PA view: To visualize whole lungs
40o caudal-cranial view: To visualize trunk & bifurcation of pulm arteries
b) Selective pulm arteriogram - Place tip of catheter in each main pulm artery
- Rt lung: LPO 10o, Lt lung: RPO 10o
- Remove sheath, compression
Aftercare 1. Monitor puncture site for bleeding / haemorrhage
2. Monitor vital signs
Complication 1. Respiratory distress, major dysrhythmias
2. General complications of CM
3. General complications of angiography
Mortality rate: 0.2 – 0.5%
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A. Apical branch
B. Left pulmonary artery
C. Right pulmonary artery
D. SVC
E. Lingular branch
F. Middle lobar branch of pulmonary
artery
G. Inferior lobar branch of pulmonary
artery
H. Pulmonary trunk
I. Right atrium
J. Right ventricle
K. IVC
A. Apico-posterior branch
B. Apical branch
C. Inferior pulmonary vein
D. Superior pulmonary vein
E. Common basal vein
F. Right atrium
G. Left atrium
H. Inferior basal vein
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B. Bronchial Arteriography
Indications Indications: Contraindications:
Diagnosis & embolic treatment of haemoptysis 1. No absolute, bleeding tendency
(Bronchial arteries embolization, BAE) 2. CIx for IV contrast media & ionizing radiation
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter:
Contrast IV LOCM-370
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral artery
- Perform an aortogram, for identification of the bronchial arteries (usually at T5 / T6 level)
- Cannulate bronchial arteries (if they arise from it) & perform angiographic (digital subtraction) runs
Embolization of bronchial arteries
- Remove sheath, compression
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. Spinal ischamia
If the intercostal artery (which gives out medullary branch of the anterior spinal artery) shares the same origin with
the embolized bronchial artery
2. General complications of CM
3. General complications of angiography
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GASTRO-INTESTINAL TRACT
A. Arteriography of Coeliac Axis, Superior Mesenteric & Inferior Mesenteric Artery
Indications Indications: Contraindications:
1. GI bleed (only demonstrable if bleeding >0.5ml/min) 1. No absolute, bleeding tendency
2. GI ischaemia 2. CIx for IV contrast media & ionizing radiation
3. Tumour embolization
4. Portal venography (CT/MR shows portal system well)
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter: Simmons (Sims) / Sidewinder or Cobra catheter
Contrast IV LOCM 320-370
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral artery
- May give IV Buscopan 10-20mg to ↓ bowel movement
- Cannulate artery (Sidewinder / cobra catheter) & perform angiographic (digital subtraction) runs:
a) Coeliac axis - T12/ L1 level
- Contrast: 35 mls, 6 mls/sec
- May perform selective run for splenic, dorsal pancreatic, gastroduodenal art
b) SMA - L1 level
- Contrast: 42 mls, 7 mls/sec
c) IMA - L3 level
- Patient in 30o LPO (to open the sigmoid loop)
- Contrast: 10 mls, 4 mls/sec
d) Portal vein - Delayed venous phase of coeliac & SMA
- Remove sheath, compression
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. General complications of CM
2. General complications of angiography
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B. Portal Venography
Indications Indications: Contraindications:
1. Assess patency of portal venous system 1. No absolute
2. Assess patency of porto-systemic anastomosis 2. CIx for IV contrast media & ionizing radiation
3. Demonstrate anatomy of portal system before operation
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Coeliac / SMA approach: Simmons (Sims) / Sidewinder or Cobra catheter
4. Trans-splenic approach: Longdwell needle (20G & 10cm with stilette & outer plastic sheath)
Contrast LOCM-370, 50mls
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique Approaches for portal venography:
a) Venous phase of coeliac / SMA angiography
b) Trans-splenic approach
c) Transjugular-transhepatic approach
d) Paraumbilical vein catheterization
Trans-splenic approach
- Supine position
- Identify puncture site: Mid-axillary line, 10th – 11th intercostal space
- LA infiltrated, under US guidance
With patient suspend respiration, insert Longdwell puncture needle,
advance inwards & upwards into spleen, till 3⁄4 of needle inserted
- Remove needle & stilette, leaving the plastic canulla in-situ, patient can breathe shallowly
Observe for blood flowing back, if position is correct
- Small volume of manual test injection of CM, to ensure correct position
- Perform a digital subtraction angiographic run (1 frame/sec):
Hand inject CM 50mls in 5sec
Remove cannula as soon as possible, after CM injection
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication Trans-splenic approach
1. Extra-capsular injection → Pain
2. Sub-capsular injection
3. Haemorrhage
4. Splenic rupture
5. Perforation of adjacent structures (pleura, colon)
6. General complications of CM
7. General complications of angiography
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BILIARY SYSTEM
A. Endoscopic Retrograde Cholangio-pancreaticography (ERCP)
Indications Indications: Contraindications:
1. Diagnostic for pt unsuitable for MRCP 1. Upper GI obstruction (oesophagus, pylorus, duodenum)
2. Assessment & therapeutic for 2. Previous gastric surgery, that prevents access to duodenum
(i) Bile duct stones 3. Severe cardiac / respiratory disease
(ii) Biliary strictures 4. CIx for IV contrast media & ionizing radiation
(iii) Ampullary lesions
(iv) Chronic pancreatitis
(v) Post-cholecystectomy
3. Ix for diffuse biliary disease (sclerosing cholangitis)
Contrast 1. Pancreas: LOCM 240-300
2. Bile ducts: LOCM-150 (to prevent obscuration of calculi)
Preparation NBM for 6hrs
Pre-procedure antibiotic
Technique - Endoscopic & fluoroscopic facility
- Prelim: Prone AP or LAO of upper abdomen, to assess calculi
- Sitting position
Pharynx is anaesthetized wt lidocaine spray
Sedation may be required
- Left lateral position
Introduce endoscope, till ampulla of Vater
- Prone position
Insert polythene catheter (prefilled wt CM) into ampulla
Small test injection of CM to confirm position
- Inject CM into pancreatic duct (if indicated)
Spot films taken: Prone, LPO, RPO
- Inject CM into biliary tree
Spot films taken:
a) Prone AP, LPO, RPO
b) Supine PA, LAO, RAO
Trendelenburg, to fill intrahepatic ducts
Semi-erect, to fill lower CBD & GB
- Remove endoscope, spot films taken, to assess duct obscured by endoscope
Delayed films, to assess GB & emptying of CBD
Aftercare NBM till pharyngeal sensation returns
Monitor vital signs for 6hrs
Continue antibiotics, if there is biliary / pancreatic obstruction
Complication 1. Injury d/t manipulation of endoscope (oesophagus, ampulla, proximal pancreatic duct, distal CBD)
2. Acute pancreatitis
3. Bacteraemia, septicaemia
4. Aspiration
5. Allergic / idiosyncratic reactions d/t CM
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B. Intra-operative Cholangiography
Indications Indications: Contraindications:
Assessment of CBD, during cholecystectomy or bile duct surgery, None
to avoid surgical exploration of CBD (MRCP is preferred prior to surgery)
Contrast HOCM or LOCM-150 (to prevent obscuration of calculi): 20mls
Preparation As for surgery
Technique - Operating theatre wt II
- Cannulate cystic duct, wt catheter prefill wt CM
- Inject CM 5mls, spot film taken
- Inject CM 20mls, to demonstrate flowing of CM into duodenum, spot film taken
May give IV Glucagon / Propantheline / Amyl nitrite, to relieve spasm of sphincter of Oddi
- Le Quesne criteria for normal intra-operative cholangiogram:
a) CBD ≤ 12mm
b) No filling defects
c) The terminal narrow segment of the duct is clearly seen
d) Free flow of CM into duodenum
e) No excess retrograde filling of hepatic ducts
Aftercare As for surgery
Complication As for surgery
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Chiba needle:
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F. Hepatic Arteriography
Indications Indications: Contraindications:
1. To assess vascular & liver lesions 1. Bleeding tendency
2. Preliminary to hepatic artery embolization 2. CIx for IV contrast media & ionizing radiation
a) Traumatic bleeding, blood-bile fistula
TACE:
b) Benign liver tumour 1. Severe liver / renal impairment
c) Primary liver tumour (TACE) 2. Biliary obstruction
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter: Rosch hepatic / Yashiro catheter
Contrast IV LOCM 320-370
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique Embolization of hepatic artery branches does not cause infarction, d/t dual supply of liver
→ Important to demonstrate portal vein patency before embolization
- Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral artery
- Cannulate coeliac axis (Sidewinder / cobra catheter) & perform a portal venography (delayed venous phase) runs:
- After demonstration of portal vein patency, proceed with hepatic arteriography
- Cannulate common hepatic artery (Rosch hepatic / Yashiro catheter) & perform angiographic runs
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GENITO-URINARY TRACT
A. Percutaneous Nephrostomy Tube Insertion
Indications Indications: Contraindications:
1. Obstructive uropathy 1. Bleeding tendency
2. Pyonephrosis 2. CIx for contrast media & ionizing radiation
3. Prior to PCNL
Contrast HOCM or LOCM-150 (to prevent obscuration of small lesions)
Preparation NBM for 4hrs
Normal blood Ix: FBC, RP, PT/APTT
May need pre-procedure antibiotic
Equipment 1. Puncture needle (18G) / Coaxial needle
(Angio suite 2. Guidewire: Hydrophilic / Stiff Amplaz
wt US) 3. Drainage catheter: Pigtail catheter (8Fr for draining urine, 10-12Fr for draining pus)
Technique - Prone / oblique position with pillow placed under the abdomen, Clean & drape
- Identify puncture site: Posterior axillary line, below 12th rib
- LA infiltrated wt spinal needle, under US guidance
Insert puncture needle, advance towards mid / lower pole of kidney, into pelvicalyceal system
Lower pole of kidney Safer (↓ Risk of puncturing lung / pleura)
Brodel’s avascular line - Avascular plane btw anterior & posterior segmental branches of renal artery
- 1-2cm posterior to convex border of kidney (Mid-lateral border of kidney)
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E. Renal Arteriography
Indications Indications: Contraindications:
1. Renal artery stenosis, prior to angioplasty / stenting 1. No absolute, bleeding tendency
2. Renal tumour, prior to embolization 2. CIx for IV contrast media & ionizing radiation
3. Renal injury (trauma, iatrogenic), prior to embolization
4. Potential renal transplant donor
Diagnostic renal arteriogram has been replaced by
MRA / CTA
Equipment 1. Digital fluoroscopy wt angiography facility
2. Pump injector
3. Catheter:
a) Flush aortogram: Pigtail catheter 4Fr
b) Selective arteriogram: Simmons (Sims) / Sidewinder or Cobra catheter
Contrast 1. Flush aortogram: IV LOCM-300 40-50 mls, 20-25 mls/sec
2. Selective arteriogram: IV LOCM-300 10 mls, 5 mls/sec
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral artery
- Approach:
a) Flush aortogram
- Start wt flush aortogram,
to assess normal anatomy / variants (accessory renal artery),
as selective renal arteriogram may miss lesion at origin of renal artery
- Place tip of pigtail catheter proximal to renal vessels (T12 level)
- Contrast: 40-50 mls, 20-25 mls/sec
- Perform angiographic (digital subtraction) runs: AP & oblique
b) Selective renal arteriogram
- After flush aortogram, for better assessment of renal vasculature
- Place tip of Sidewinder / Cobra catheter at the selected renal artery (L1 / L2 level)
- Contrast: 10 mls, 5 mls/sec
- Perform angiographic (digital subtraction) runs
- Remove sheath, compression
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. General complications of CM
2. General complications of angiography
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1. Splenic artery
2. Arcuate arteries
3. Interlobular arteries
4. Superior segmental artery
5. Segmental arteries – Anterior branch
6. Inferior adrenal artery
7. Segmental arteries – Posterior branch
8. Middle segmental artery
9. Inferior segmental artery
10. Right renal artery
11. Left renal artery
12. Abdominal aorta
1. Interlobular vein
2. Renal vein – Superior branch
3. Arcuate vein
4. Left renal vein
5. Right renal vein
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F. Renal Venography
Indications Indications: Contraindications:
1. Renal vein thrombosis / compression 1. No absolute, bleeding tendency
2. Renal tumour, to detect invasion of renal vein / IVC 2. CIx for IV contrast media & ionizing radiation
3. Potential renal transplant donor, to detect venous abN
4. Congenital anomalies
(congenital renal agenesis, small contracted kidney)
Equipment 1. Digital fluoroscopy wt angiography facility
2. Catheter: Simmons (Sims) / Sidewinder or Cobra catheter
Contrast IV LOCM-300
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral vein → IVC → Selective renal vein injection
- Remove sheath, compression
Aftercare 1. Pressure at venopuncture site
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
Complication 1. General complications of CM
2. General complications of angiography
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BRAIN
A. Cerebral Angiography
Indications Indications: Contraindications:
1.Cerebral ischaemia 1. No absolute, bleeding tendency
2. ICB (SAH & intraparenchymal bleed) 2. CIx for IV contrast media & ionizing radiation
3. Vascular malformation (AVM, aneurysm, CCF)
4. Pre-op assessment of intracranial tumours
Equipment 1. Digital fluoroscopy wt angiography facility (with road map & DSA functions)
2. Pump injector
3. Puncture needle: 18G
4. Femoral sheath: 4-5 Fr
5. Guidewire: Terumo glidewire 0.035” (150cm)
6. Catheter:
a) Younger patient: Vertebral catheter
b) Older patient: Simmons (Sims) / sidewinder catheter or Headhunter or JB 2 or MANI
(Better torque control to pass through atherosclerotic & torturous vessel)
Contrast LOCM
Preparation NBM for 6hrs
Normal blood Ix: FBC, RP, PT/APTT
May require sedation / GA (paeds or uncooperative patients)
Technique - Supine position, clean & drape, LA infiltrated
- Puncture site (modified Seldinger technique): Femoral artery
- Perform an arch aortogram (to identify the branches of aortic arch), then proceed with selective studies:
Small volume of manual test injection of CM, before pump injection (to ensure catheter tip is not in coronary art)
Catheter tip parked at Contrast volume, mls Flow rate, mls/sec Frame rate, f/sec
a) Arch aortogram 1-3cm above aortic valve 30-40 15-20 6
b) CCA C4 (before bifurcation) 12 6 2-4
c) ICA (if indicated) C2 10 5 2-4
d) ECA (if indicated) C4 4 2 2-4
e) Vertebral art 6 3 2-4
- Image acquisition:
a) Arch aortogram: PA & RPO view (to open out aortic arch)
b) Selective studies:
Projections Basic: AP axial / FO 30o (Towne), lateral
Additional: OM view, oblique views
Phases Early & late: Arterial, capillary, venous
- Extra precautions must be taken to prevent embolic ischaemic event
- Remove sheath, compression
Aftercare 1. Bed rest for 4-6hrs (femoral art puncture)
2. Monitor puncture site for bleeding / haemorrhage
3. Monitor vital signs
4. Observe for signs of cerebral ischaemia
Complication 1. Cerebral ischaemia / infarction d/t embolism
a) Dislodged atherosclerotic plaque / arterial thrombus
- Never pass a guidewire / catheter through vessel that has not been visualized by prelim injection of CM
- Gentle manipulation of guidewire / catheter
- Use microcatheter to negotiate through sharp curves
b) Thrombus within catheter
- Flush the catheter regularly wt NS
- Never leave guidewire within a catheter >1min without withdrawal / flushing
- Never insert guidewire into a catheter filled wt CM ( must flush wt NS 1st)
b) Air
- Ensure all connectors are tight
- Always suck back when syringe is connected to catheter
- Ensure air bubbles are expelled from syringe, before injection
- Keep the syringe vertical, when injecting
c) Injected solutions (blood clot, cotton fiber, glove powder)
- Avoid contamination of NS / CM by blood clot, cotton fiber, glove powder
d) Embolic material used for embolization
2. ICB d/t arterial dissection by guidewire / catheter
3. General complications of CM
4. General complications of angiography
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Arch aortogram
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Arch aortogram
1. Callosomarginal art 12. Anterior choroidal art 1. Posterior internal frontal art 12. Posterior temporal art
2. Anterior parietal art 14. MCA – 2nd segment 2. Anterior parietal art 13. Prefrontal arteries
3, 5, 8, 13. Pericallosal art 15. Anterior comm art 3. Paracentral art 14. MCA – 2nd segment
4. Posterior parietal art 16. MCA – 1st segment 4. Posterior parietal art 15. ACA – 2nd segment
6. Frontal polar art 17. Temporal polar art 5. Anterior internal frontal art 16. Anterior choroidal art
7. Precentral sulcal art 18. Frontal orbital art 6. Superior internal parietal art 17. Frontal orbital art
9. Artery of angular gyrus 19. Ophthalmic art 7. Medial internal frontal art 18. Posterior comm art
10. Posterior temporal art 20. ICA 8. Interior internal parietal art 19. Ophthalmic art
11. Prefrontal arteries 9. Frontal polar art 20. ICA
10. Antery of angular gyrus 21. Callosomarginal art
11. Pericallosal art
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1. Parietal vein 8. Frontal veins 1. Superior sagittal sinus 13. Inf anastomotic v (Labbe)
2. Superior sagittal sinus 9. Veins of fossal of Sylvian 2. Parietal vein 14. Veins of fossa of Sylvian
3. Sup anastomotic v (Trolard) 10. Sphenoparietal sinus 3. Sup anastomotic v (Trolard) 15. Confluence of sinuses
4. Great cerebral v (Galen) 11. Transverse sinus 4. Occipital veins 16. Cavernous sinus (anterior)
5. Internal cerebral vein 12. Intercavernous sinus 5. Inferior sagittal sinus 17. Transverse sinus
6. Sup thalamostriate vein 13. Inferior petrosal sinus 6. Internal cerebral vein 18. Superior petrosal sinus
7. Basal vein of Rosenthal 14. Sigmoid sinus 7. Sup thalamostriate veins 19. Cavernous sinus (posterior)
8. Vein of septum pellucidum 20. Sigmoid sinus
9. Straight sinus 21. Inferior petrosal sinus
10. Great cerebral v (Galen) 22. Occipital sinus
11. Ascending frontal veins 23. Pterygoid plexus
12. Basal vein of Rosenthal 24. IJV
1. Med occipital a – Calcarine br 7. Sup cerebellar art 1. Parieto-occipital art 8. Posterior comm art
2. Parieto-occipital art 8. Marginal art 2. Dorsal corpus callosal branch 9. Sup cerebellar art
3. Vermis branch 9. AICA 3. Med occipital a – Calcarine br 10. Basillar art
4. Thalamoperforate arteries 10. Basilar art 4. Choroidal arteries 11. AICA
5. PCA 11. PICA 5. Temporo-occipital art 12. PICA
6. Temporo-occipital art 12. Vertebral art 6. PCA 13. Vertebral arteries
7. Post artery to thalamus
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1. Straight sinus 7. Inf v of cerebellar hemisphere 1. Sup v of cerebellar hemisphere 8. Transverse sinus
2. Superior cerebral veins 8. Petrosal vein 2. Great cerebral v (Galen) 9 & 11. Inf v of cerebellar
3. Confluence of sinuses 9. Sigmoid sinus 3. Internal cerebral vein hemisphere
4. Transverse sinus 10. Bulb of jugular vein 4. Straight sinus 10. Cavernous sinus
5. Veins of cerebral hemisphere 11. Inferior petrosal sinus 5. Basal vein of Rosenthal 12. Superior petrosal sinus
6. Inferior vein of the vermis 6. Precentral cerebellar vein 13. Inferior petrosal sinus
7. Confluence of sinuses 14. Sigmoid sinus
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2. Parathyroid glands
- Position: Supine, neck extended
- Technique: Rt & Lt paramedian, transverse & longitudinal
- Appearance: Normal parathyroid glands are not visualized d/t their small size
Posterior to thyroid gland, hypoechoic to thyroid gland
3. Other structures
a) Neck vessels (carotid artery & IJV)
b) Salivary glands
c) Lymph nodes
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B. Salivary Glands
Indications 1. Symptoms: Pain, swelling, mouth dryness
2. Mumps
3. AbN radiological findings (XR, CT, sialogram)
Equipment Linear probe, 5 – 7.5 MHz
Technique 1. Parotid gland
- Position: Supine, neck extended
- Technique: Parotid region, transverse & longitudinal
- Colour duplex: Assess vascularity
- Appearance: Homogenous echotexture, hypoechoic
Normal duct is not usually visualized unless dilated
2. Submandibular gland
- Position: Supine, neck extended
- Technique: Submandibular region
- Colour duplex: Assess vascularity
- Appearance: Homogenous echotexture, hypoechoic
Normal duct is not usually visualized unless dilated
3. Sublingual gland
- Position: Supine, neck extended
- Planes: Midline submantel, transverse
Inferior to tongue, anterior to submandibular gland
- Colour duplex: Assess vascularity
- Appearance: Very small glands, may not be able to visualize
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GASTRO-INTESTINAL TRACT
A. Stomach
Indications Pyloric stenosis (Paediatrics)
Equipment 5 – 7.5 MHz linear probe
Technique - Supine position
- If stomach is distended, insert NG tube
- Give some dextrose, via mouth or NG tube, to distend the antrum
- Scan pylorus in:
a) Longitudinal plane Olive shape
b) Transverse plane Doughnut shape
- Visualize:
a) Muscle Hypoechoeic
b) Mucosa Hyperechoeic
c) Antral peristalsis
- Measurement
a) Muscle thickness, muscle thickness : wall diameter ratio
b) Canal length
c) Pyloric volume
B. Small Bowel
Indications 1. Obstruction
2. Inflammation
3. Midgut Malrotation / Volvulus
Equipment 5 – 7.5 MHz linear probe
Technique - Obstruction: Dilated small bowel loops
- Inflammation: Thickened bowel wall, ↑ vasculation
- Malrotation: Altered normal relationship of SMA & SMV (Normal: SMV anterior & Rt of SMA)
C. Appendix
Indications Appendicitis & complications
Equipment 5 – 7.5 MHz linear probe
Preparation Preferably NBM 6hrs
Technique - Position: Supine
- Technique: RIF, start with transverse plane, press transducer to displace bowel loops
May look for external iliac vessels as anatomical landmark
- Features:
Features Normal appendix Appendicitis
Appearance Compressible, exhibit peristalsis Non-compressible, lack of peristalsis
Measurement
a) Diameter ≤ 6mm > 6mm
b) Wall thickness < 3mm ≥ 3mm
Associated findings - Appendicolith
Echogenic surrounding fat
Periappendiceal collection
Enlarged nodes
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D. Liver
Indications 1. Symptoms: RHC pain, jaundice, PUO 5. Surveillance for hepatitis
2. Hepatomegaly 6. Suspected portal HPT
3. Deranged LFT 7. Assessment of portal vein, hepatic artery / veins
4. Liver pathology (fatty liver, hepatitis, tumour) 8. Staging of known extrahepatic malignancy (breast ca)
Equipment Curvilinear probe, 3 – 5 MHz
Technique - Position: Supine or Lt lateral decubitus
- Area: Epigastric, subcostal / Rt intercostals
- Planes: Longitudinal & transverse
- Echogenicity (PLiSK): Pancreas > Liver > Spleen > Kidney
b) Right lobe
Technique Rt parasagittal, longitudinal (see Rt liver lobe & Rt kidney)
Rt intercostal, oblique (see middle & Rt hepatic vein)
Rt subcostal, oblique (see Rt portal vein)
Measurement Rt lobe span < 16cm
- At Rt parasagittal (mid-clavicular line), longitudinal
- From diaphragm – lower liver edge
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2. Portal vein
Technique Main portal vein: Rt Subcostal & Rt intercostal, oblique
Rt & Lt portal vein: Epigastric & Rt intercostal, transverse
Features Echogenicity of portal vein walls > liver parenchyma
Diameter (main portal vein) ≤ 1.3cm
Doppler Waveform: Continuous forward flow wt respiratory variation (↑on inspiration)
Normal: Hepatopetal flow (Flow towards liver)
Portal HPT: Hepatofugal flow (Flow reversal)
Venous flow: 10 – 20 cm/sec
3. Hepatic vein
Technique Epigastric & Rt intercostal, transverse
Features Echogenicity of hepatic vein walls ≤ liver parenchyma
Diameter (distal to last confluence before IVC) ≤ 0.6cm
Doppler Waveform: Triphasic waveform, d/t reflection from Rt atrial events (same as IVC)
4. Hepatic artery
Technique Traced from celiac axis, transverse
Features Seagull appearance (common hepatic or splenic arteries)
Doppler Forward flow, throughout systolic & diastolic, wt sharp systolic peak
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2. Intrahepatic ducts
Technique Lt lobe: Epigastric, transverse
Rt lobe: Subcostal / Rt intercostal, oblique
Features of Beaded branching appearance
dilated ducts Diameter >40% of accompanying PV branch
3. Extrahepatic ducts
Technique CBD: Subcostal / Rt intercostal, oblique, anterior to PV
Extends downwards through head of pancreas to ampulla
Features CHD ≤ 4mm
CBD ≤ 6mm (Post-cholecystectomy ≤ 10mm)
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F. Pancreas
Indications 1. Pancreatic tumour 4. Epigastric pain
2. Pancreatitis & its complications 5. Jaundice
3. Epigastric mass
Equipment Curvilinear probe, 3 – 5 MHz
Technique - Position: Supine, may perform in right / left oblique or erect position
Drinking water may improve the window through the stomach
- Appearance: Homogenous, iso-hyperechoic to liver
- Planes:
Body Epigastric, transverse, anterior to splenic vein
Head & tail Epigastric, angle transversely & obliquely
Tail Lt intercostal, oblique, wt spleen as acoustic window
- Measurement:
AP diameter Head < 35mm Pancreatic duct In the head ≤ 3mm
Neck 10-15mm In the body ≤ 2mm
Tail < 20mm
G. Spleen
Indications 1. Symptoms: PUO 4. Splenic pathology (mass, infarction, haematoma)
2. Splenomegaly 5. Portal HPT, varices
3. Infection/inflammation (abscess)
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GENITO-URINARY TRACT
A. KUB
Indications 1. Renal pathology 2. Bladder pathology
a) Renal mass a) Bladder mass
b) Renal parenchymal disease b) Obstructive uropathy
c) Obstructive uropathy c) Neurogenic bladder
d) Assessment of renal graft (Bladder volume before & after micturition)
e) Young HPT 3. Prostate: Ca, BPH
f) UTI: Pyelonephritis, pyelonephrosis, recurrent UTI
g) Haematuria
Equipment Curvilinear probe, 3 – 5 MHz
Preparation May require full bladder
Technique 1. Kidney
- Position: Supine, Rt & Lt lateral decubitus
- Technique: Right kidney: Right loin, longitudinal & transverse
Left kidney: Left loin, longitudinal & transverse
Renal graft: Usually RIF, longitudinal & axial
- Measurement:
a) Bipolar length (BPL) 9 – 12 cm (usually left kidney is larger)
Lt & Rt discrepancy should be ≤ 1.5cm
b) Parenchymal thickness (PT) Usually ≥ 1cm
2. Bladder
- Position: Supine (with full bladder)
- Technique: Suprapubic, transverse & longitudinal
- Measurement:
Wall thickness ≤ 3mm
Volume (0.52 x APxWxCC): Residual urine < 100 cm3
Pre- & post-micturition (< 10% pre-micturition volume)
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3. Prostate gland
- Position: Supine (with full bladder)
- Technique: Suprapubic angle inferiorly, transverse & longitudinal
- Measurement:
Volume (0.52 x APxWxCC) 5 x 3 x 3 cm (≤ 25 mls)
2. Ovaries
- Position: Supine (with full bladder)
- Technique: Suprapubic, transverse & longitudinal, pivot Rt & Lt to look for each ovary
- Measurement:
Ovarian volume < 10 cm3
Simple ovarian cyst diameter < 30 mm
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C. Scrotum
Indications 1. Symptoms: Pain, swelling Testicular mass 5. Undescended testis
2. Mass: Malignancy, Hydrocoele, Vericocoele 6. Scrotal trauma
3. Infection: Epididymo-orchitis 7. Infertility
4. Acute testicular torsion
Equipment Linear probe, 7.5 – 15 MHz
Technique - Position: Supine, tuck the penis up over the symphysis
1. Testis
- Technique: Each testis, transverse & longitudinal
- Colour duplex: Assess vascularity
- Comparison view that includes both testes
- Appearance: Homogenous echogenicity
- Measurement: Testicular volume > 10 cm3
2. Epididymis
- Technique: Each epididymis, transverse & longitudinal
Locate the head in transverse plane, then scan downward to body & tail
- Colour duplex: Assess vascularity
- Measurement: Epididymal thickness < 3mm
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OBSTETRIC
A. Fetus
1. Gestational sac & Yolk sac
- Appearance:
Gestational sac - Appears during 4th week (on transvaginal scan)
- Echogenic ring surrounding an anechoic centre, within the endometrial cavity
Yolk sac - Appears during 5th week
- Echogenic ring surrounding an anechoic centre, within the gestational sac
- Measurement: Average gestational sac diameter of 3 dimensions (AP,W,CC)
→ To determine gestational age before fetal pole (crown rump length) can be seen
- Appearance (fetal pole): A mass of fetal cells within the yold sac, appears during 6th week
- Measurement (crown rump length): Longest fetal diameter, from fetal head – fetal rump
→ To determine gestational age until 12th week (replaced by biparietal diameter)
- Plane: Transverse (must include cavum septum pellucidum, thallamus & choroid plexus in the lateral ventricles)
- Measurement:
BPD Measure diameter, from outer table (of near calvarium) to inner table (of far calvarium)
→ To determine gestational age from 12th – 20th weeks
HC Measure around the skull outer table
→ To determine gestational age if there is variant head shape
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4. Abdominal Circumference
- Plane: Transverse (must include portal section from umbilical vein, stomach & true cross section of spine wt 3 ossification centres)
- Measurement: Measure around the abdomen
5. Femur Length
- Plane: Can only be measured when femur is horizontal (beam is perpendicular) and shadows evenly from both ends
- Measurement: Measure the entire femur
a) Heart beat: Beating heart on B-mode, subtle flicker on M-mode (avoid Doppler during early pregnancy)
b) M-mode heart rate
c) Normal situs: On the left
d) Normal anatomy: 4 chambers & valves, RVOT, LVOT, interventricular septum, 3 great vessels (pulm art, aorta, vene cava)
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B. Maternal
1. Cervix
2. Placenta
- Appearance: Long & thin echogenic tissue (lining the inner uterine surface) wt homogenous echotexture
- Assessment:
Location - Anterior or posterior
- Distance btw placental tip & internal os > 3mm
Myometrial rim Space under the placenta ≥ 3mm
(otherwise suspect placenta percreta / accreta)
Definition:
Deepest vertical pocket (wt no fetal content) in each quadrant,
then add them up together
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PAEDIATRICS
A. Cranium
Indications 1. Intracranial pathology
2. Congenital anomalies
3. ICB (germinal matrix haemorrhage, extra-axial haemorrhage)
4. Hydrocephalus
Equipment 1. Sector probe, 4-7 MHz
2. Linear probe, 7.5-10 MHz (to visualize superficial structures)
Approach
Planes:
a) Coronal
Images: Structures seen:
1. Frontal lobes (ant to frontal horns) Frontal lobes, optic ridge
2. Frontal horns of lateral ventricles Frontal horns, cavum septum pellucidum,
corpus callosum, thalami, basal ganglia
3. 3rd ventricle & thalami 3rd ventricle, foramen Monro,
thalami, basal ganglia, brainstem
4. Bodies of lateral ventricles Bodies & temporal horns of lateral ventricles
5. Trigone of lateral ventricles Trigone, choroid plexus,
periventricular white matter blush
6. Occipital lobes Occipital & parietal lobes
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b) Sagittal
Measurement:
a) Ventricular index:
Ratio of distance btw lateral sides of lateral ventricles & biparietal diameter
b) Subarachnoid space:
- Appearance: Anechoic, has vessels crossing
(as opposed to subdural space)
- Measure on coronal plane, wt linear transducer
- Normal: < 3.3mm
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Cranial vasculature:
a) Arteries (ICA, MCA, COW)
- Technique: Anterior fontanelle, coronal plane
- Measure: PSV, EDV, Resistive index
↓ RI Acute ischaemia
↑ RI Cerebral oedema (ICP > systemic pressure)
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B. Thorax
Indications 1. Opaque hemithorax on CXR
2. Guidance for thoracic intervention
Equipment Neonates & infant: Linear probe, 7.5-10 MHz
Children & adolescent: Curvilinear probe, 3 – 5 MHz
Technique - Position: Decubitus, supine, prone
Parts examined Approach
Lung, pleura, ant mediastinum Transternal, parasternal, intercostal
Lung apex, sup mediastinum Suprasternal, supraclavicular
Juxtaphrenic paravertebral lesion Subxiphoid, transdiaphragmatic
- Normal findings:
1. Thymus Well-defined homogenous structure, at ant & sup mediastinum, in transverse plane
2. Hyperechoic: Pleural line, air, diaphragm, periosteum
Hypoechoic: Fluid, blood
3. Pleural line Horizontal echogenic line btw 2 ribs, in longitudinal plane over intercostal space
4. Bat sign - Superior and inferior ribs, their acoustic shades (the wings of the bat)
- Pleural line and the lung underneath (the body of the bat)
5. Lung sliding - Lung sliding against the thoracic wall, concordance wt respiration
(seashore sign) - Seen as seashore sign on M-mode
- Normal artifacts:
1. A lines Echogenic horizontal lines, parallel with the pleural line, d/t reverberation artefact
2. B lines Echogenic vertical lines, arising from pleural line, which move wt lung sliding
3. Mirror image Duplicated image d/t reflection by diaphragm
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C. Abdomen
Indication Hypertrophic pyloric stenosis
Equipment 1. Sector probe, 4-7 MHz
2. Linear probe, 7.5-10 MHz
Preparation NBM 4hrs (to avoid obscuration by gastric gas)
May feed water before examination (to create good acoustic window)
Technique 1. General abdominal examination
2. Assess for pyloric stenosis
- Area: Epigastric, supine position
May roll baby to right decubitus (to promote fluid towards & gas away from pylorus)
- Planes: Longitudinal & transverse plane of the pylorus
Assessment: Normal Pyloric stenosis
Relation of pylorus to GB Distant away from GB Displaced to lie adjacent to GB
Appearance Muscle: Hypoechoic Hypertrophic muscle
Mucosa: Hyperechoic (hypoechoic)
Pyloric canal Water/milk may pass through Closed
Measurement Special sign:
a) Transverse diameter < 13mm Target sign
b) Longitudinal length < 15-17mm Antral nipple sign
c) Pyloric muscle thickness < 3mm Cervix sign
(single muscular wall on transverse)
- If pylorus is normal → Examine for midgut malrotation / volvulus
Normal
Pyloric stenosis
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Normal Malrotation
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Indication Intussusception:
Forward peristalsis causing invagination of more proximal bowel (intussusceptum) into more distal bowel (intussuscipiens)
Equipment 1. Sector probe, 4-7 MHz
2. Linear probe, 7.5-10 MHz
Preparation Ensure adequate hydration
Technique 1. General abdominal examination
2. Assess for intussusception
- Position: Supine
- Technique: Start scanning at RIF in transverse plane of the bowel, then move distally along the large bowel
If intussusception is seen, scan in longitudinal plane
Assessment:
a) Signs of intussusception Pseudokidney sign, Target/doughnut sign, Crescent in doughnut sign
b) Parts of intussusception (i) Intussusceptum – The proximal loop which enters into intussuscipiens
(ii) Intussuscipiens – The distal loop which receives intussusceptum
(iii) Apex – The part which advances (most distal part of intussusceptum)
c) Type of intususception (i) Ileocolic (most common)
(ii) Ileoileocolic (2nd most common)
(iii) Ileoileal
(iv) Colocolic
d) Others (i) Vascularity (risk of ischemia & irreducibility if diminished)
(ii) Trapped fluid within intussusception (risk of ischemia & irreducibility)
(iii) Intraperitoneal free fluid (may be d/t inflammation or perforation)
(iv) Lead point: Enlarged nodes, inflammation, neoplasm (but mostly idiopathic)
- Proceed to ultrasound-guided hydrostatic reduction if no contraindication
- During & post-procedure ultrasound
Assessment:
a) Dissection sign Fluid dissecting btw intussusceptum & intussuscipiens
(indicator of failed reduction)
b) Signs of perforation Increase intraperitoneal free fluid → Stop reduction if present
c) Successful reduction Resolution of the soft tissue mass
Free reflux of fluid/gas into small bowel, via ileocaecal valve (fishmouth)
Dissection sign Intraperitoneal free fluid Free reflux of fluid into small bowel
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C. Hip
Indications 1. Development dysplasia of the hip (DDH)
≤ 6mths US can identify the bony acetabulum & unossified elements
(femoral head, labrum, triradiate cartilage)
After 9-12mths Ossification takes place → Plain radiograph more superior
2. Slipped femoral capital epiphysis (SUFE)
3. Hip effusion (Septic arthritis, haemarthrosis)
Equipment Linear probe, 7.5-10 MHz
Planes 1. Coronal view 2. Transverse flexion view
- Probe parallel to lateral aspect of the hip - Probe perpendicular to lateral aspect of the hip
- To assess hip effusion & DDH (static) - To assess DDH (dynamic)
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Ortolani manoeuver Thigh abducted & external rotated (wt hip & knee flexed)
→ To assess reducibility of the hip (after dislocation during Barlow)
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D. Spine
Indications 1. Suspect spinal abnormalities / neural tube defects
- Midline skin dimple, tufts of hair
- Anorectal anomalies
- Posterior midline mass
2. Trauma
3. Infection / abscess
Equipment Linear probe, 7.5-10 MHz
Technique - Position: Prone / lateral decubitus
- Planes: Longitudinal & transverse
Longitudinal - From mid-thoracic to sacro-coccygeal region, in midline & side-to-side
- Assess:
a) Posterior neural arch: Intact, paired, uniform
b) Level of conus medullaris (Not lower than L3)
- Count from iliac crest (L4) upward
- Count from Lumbo-sacral junction (L5/S1) upward
- Count from 12th rib (T12) downward
c) Filum terminale: Thin (2mm) parallel lines, from conus to end of thecal space (≈ S2 level)
d) Cauda equina: Symmetry, at dependent part of thecal sac, gentle oscillating
movement
Transverse - From mid-thoracic to sacro-coccygeal region, in midline
- Assess:
a) Posterior neural arch: Intact, paired, symmetry, uniform
b) Spinal cord: Central position, shape
c) Cauda equina: Symmetry, at dependent part of thecal sac, gentle oscillating
movement
d) CSF space: Uniform
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VASCULAR
A. Carotid Doppler
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ICA vs ECA
ICA ECA
Diameter Usually larger Usually smaller
Location (arises) Usually medial Usually lateral
Branches Usually no branches Usually has small branches (superior thyroid artery)
Wave form Lower resistance Higher resistance
“Temporal tapping” No reverberations Reverberations in the trace corresponding to tapping
* Temporal tapping: Tap gently on temporal artery (anterior to the top of the ear) while sampling ECA with Doppler
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- Planes: Longitudinal
- Technique: Return to longitudinal plane of CCA, angle the probe postero-laterally, with colour mode
Vertebral artery & vein lie in btw vertebral processes as flashes of colour
- Doppler: To assess the flow
VA waveform - ↓ Resistance flow → ↑ Diastolic flow
- Flow above baseline (not below)
Antegrade Flowing towards the head (normal)
Retrograde Flowing in opposite direction (suggesting subclavian steal syndrome)
5. Adjacent structures
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2. IVC
- Position: Supine
- Technique: Rt parasagittal, longitudinal
- Appearance: IVC passes through liver wt caudate lobe anteriorly & posteriorly
IVC dilates wt expiration
- Measurement: AP diameter < 2cm
- Colour duplex: To demonstrate patency
- Doppler waveform: Triphasic waveform, d/t reflection from Rt atrial events
1st component (S) Forward flow during late diastole (atrial relaxation) & ventricular systole
2nd component (D) Forward flow during early diastolic filling
3rd component (A) Retrograde flow during late diastole (atrial contraction)
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2. SMA
- Position: Supine
- Technique: Midline (from epigastric downward), longitudinal (inferior to coeliac artery)
- Colour duplex: To demonstrate patency
- Doppler waveform: Triphasic waveform
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D. Renal Doppler
Indications Renal arterial stenosis as a cause of HPT
Equipment Curvilinear probe, 3 – 5 MHz
Preparation Preferably NBM 6hrs (to avoid vessels being obscured or compressed by bowel)
Technique 1. Direct method
a) Abdominal aorta
- Position: Supine
- Area: Midline (from diaphragm downward)
Transverse Scan inferiorly to identify renal arteries (lateral branches of abdominal aorta, after SMA)
Then change to longitudinal plane
Longitudinal At the level of renal arteries, perform colour duplex & Doppler
- Measurement:
Doppler waveform - Triphasic waveform
- ↑ Resistance flow → ↓ Diastolic flow (Diastole touch / near baseline)
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2. Indirect method
- Position: Supine, may roll patient to decubitus position to avoid bowel gas
- Technique: Right / Left loin, longitudinal
Renal graft: Usually RIF, longitudinal
- In longitudinal plane, perform colour duplex & identify the interlobar / interlobular arteries
Then perform Doppler on the interlobar / interlobular arteries of each of the 3 renal poles
- Measurement:
Doppler waveform - Rapid sharp systolic upstroke
- ↓ Resistance flow → ↑ Diastolic flow
Acceleration time (AT) < 70 msec
Resistive index (RI) < 0.7 (Adult), 0.7–1.0 (< 5yrs)
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TOMOGRAPHY
(CT)
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GENERAL PRINCIPLES
1. Types of CT scan:
a) Scan-and-view Scan 1 image, view 1 image No overlapping of images
Pb: Partial volumic
b) Sequential Scan few images, view few images Overlapping of images
(scan-and-scan)
c) Spiral / helical Scan with x-ray tube in helical movement Overlapping of images
Acquire 3 images per rotation
3. CT Number:
Tissue HU
Fluid 0
Air - 1,000
Bone +1,000
Fat - 65 to +10
Brain White matter +25
Grey matter +40
Lung - 400 to - 600
Thyroid +70 ± 10
Liver +65 ± 5
Soft Muscle +45 ± 5
tissue Spleen +45 ± 5
Pancreas +40 ± 10
Kidney +30 ± 10
Lymphoma +45 ± 10
Coagulated +80 ± 10
Blood Lysed +55 ± 5
Fluid Plasma +27 ± 2
Exudate > +18 ± 2
Transudate < +18 ± 2
CSF +15
Bone Compact bone > +250
Spongy bone + 130 ± 100
4. Image reconstruction
a) Maximum intensity projection (MIP) Building a volume, by stacking axial slices
→ Displays the volume in a different plane (usually orthogonal)
b) Multiplanar reconstruction (MPR) Building a volume, by stacking individual slices one on top of the other
→ Displays the volume in an alternative manner
Allows viewing of image in any planes (oblique), other than orthogonal planes
c) Surface 3D-rendering A threshold value of radiodensity is chosen, processed wt edge detection algorithms
→ Displays the surfaces in 3D model
Different threshold value allows different colours to represent different components
(bone, muscle, cartilage)
d) Volume 3D-rendering Transparency & colours are used for better representation of the volume
e) Image segmentation Manual or automatic removal of the unwanted structures from volume rendering image
→ Displays structures that were previously concealed (Eg. Brain, vessels)
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CONTRAST MEDIA
IV Contrast Media
1. Contrast media used: Iodine based (300mg I ml-1)
2. Dose:
a) Normal CT scan
Dose (mls) Rate (mls/sec)
Brain 50 Bolus by hand injection
Orbit 50 Bolus by hand injection
PNS 50 Bolus by hand injection
Neck 70 3
Thorax 70 3
Abdomen 100 3
Liver 4 phase 100 5
Pancreatic protocol 100 5
IVU 100 3
Renal 4 phase 100 5
Adrenal protocol 100 5
NTAP 100-120 3
Paediatrics 1 – 1.5 mls/kg
b) CT Angiogram
Dose (mls) Rate (mls/sec)
Brain 70 5
Perfusion Brain 50mls + 50mls NS 5 mls/sec + 4 mls/sec (NS)
Carotid 100 5
CTPA 70 – 100 5
Thoracic aorta 100 5
Coronary 60 – 80 5
Abdominal aorta 100 5
Renal 100 5
Mesentery 100 5
Lower Limb 120 5
Paediatrics 2 mls/kg
3. Timing:
a) Normal CT scan
Delay (sec) IVU
Brain - - Plain -
Orbit - - Nephrographic 100 – 120
PNS - - Delay bladder 5 mins
Neck 45 Renal 4 phase
Thorax 45 - Plain -
Abdomen / NTAP - Cortico-medullary(Arterial) 30
- Porto-venous 60 - Nephrographic(Venous) 60
Liver 4 phase - Excretory(Delayed) 5 mins
- Plain - Adrenal protocol
- Arterial 30 - Plain
- Porto-venous 60 - Porto-venous
- Delay liver 5mins - Delay
Pancreatic protocol
- Plain -
- Arterial 15
- Porto-venous 35
- Delay pancreas 5 mins
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2. Dose:
a) Adult: 750 – 1000 mls, 30 – 60 mins before scanning
b) Paediatrics: Gastrograffin 1%, 3 doses every 30mins
Age Volume (mls)
0 – 6 mths 40
6 – 12 mths 60
1.5 – 3.5 yrs 80
3.5 – 6yrs 120
6 – 10 yrs 170
> 10 yrs 250
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BRAIN
1. CT Brain
Indication a) Traumatic head injury (skull fracture, ICB) d) Suspected SOL
b) CVA (ischaemic & haemorrhagic) e) Suspected ↑ ICB (before lumbar puncture)
c) Intracranial infection
Exposure 120kV, 360mAs
Contrast a) Plain
b) Contrast: IV LOCM 50mls (bolus hand injection)
Position - Supine, OML ∟ Table
- Gantry tilted (~15o), Line from orbital roof to ant aspect of foramen magnum ∟ Horizontal plane
Topogram Lateral skull, Slices ║ BOS
Coverage Caudo-cranial: BOS – Vertex (orbits not included)
Technique - Spiral / helical or sequential technique
2. CT Cisternography
Indication Indication: Contraindication: Relative
a) Study of basal cisterns with CM, a) Meningitis
to demonstrate tumours in CP angle & suprasellar cisterns b) ↑ ICP
(This indication has been replaced by MRI)
b) To identify site of CSF leak before closure
Exposure 120kV, 360mAs
Contrast a) Positive contrast: Intrathecal LOCM-240, 10mls
b) Negative contrast: Intrathecal air
Technique - To promote active CSF leakage (if present) before the procedure:
Press the neck, to occlude both jugular veins for 5mins before the study
- Inject intrathecal LOCM (LOCM-240, 10mls), via lumbar puncture
- Tilt the table to head-down position, to ensure good cranial penetration
- CT brain:
a) Prone - Start wt coronal, to maximize leaking
- Axial
b) Supine - Axial, esp when CSF leakage is profuse
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4. CT Perfusion of Brain
Indication Indication: Contraindication:
a) Acute ischaemic stroke (< 9hrs of onset) a) Haemorrhagic stroke
b) Assess the potentially salvageable brain tissue b) Ischaemic stroke
(i) Onset > 9hrs
(perfusion & penumbra)
(ii) Mild stroke (NIHSS <4), Severe (NIHSS >25)
Penumbra: Area surrounding infarcted core where damage is reversible
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2. CT Cervical Spine
Indication Trauma
Exposure
Contrast Plain
Position - Supine, OML ∟ Table
- Slices ║ Disc space
Topogram Lateral neck
Coverage Cranio-caudal: C1 – T1
Technique - Spiral / helical technique
- Slices ║ Disc space
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4. CT Orbit
Indication a) Trauma
b) Infection / inflammation
c) Tumour
Exposure 120kV, 100mAs
Contrast a) Plain
b) Contrast: SOL & intracranial involvement
- IV LOCM 50mls (bolus hand injection)
Position a) Axial: Supine, OML ∟ Table
Slices ║ Hard palate
b) Coronal: Prone, neck extended
Slices ∟ Hard palate
Topogram Lateral skull
Coverage a) Axial Caudo-cranial: Orbital floor – Orbital roof
b) Coronal AP: Orbital rim – Clivus
Technique - Spiral / helical technique
5. CT PNS
Indication a) Congenital anomaly
b) Trauma
c) Infection / inflammation: Sinusitis
d) Tumour
Exposure 135kV, 200mAs
Contrast a) Plain
b) Contrast: SOL & intracranial involvement
- IV LOCM 50mls (bolus hand injection)
Position a) Axial Supine, OML ∟ Table
Slices ║ Hard palate
b) Coronal Prone, neck extended
Slices ∟ Hard palate
Topogram Lateral skull
Coverage a) Axial Caudo-cranial: Inferior maxillary sinuses – Slightly above frontal sinuses
b) Coronal AP: Anterior nose – Sphenoid sinuses
Technique - Spiral / helical technique
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2. HRCT Thorax
Indication a) Diffuse infiltrative lung disease
b) Interstitial lung pathology (Bronchiectasis)
c) Airway stenosis
Exposure 135kV, 200mAs
Contrast Plain
Position Supine, OML ∟ Table
May compliment with prone (to confirm reversible dependent changes)
Upper limbs above the head
Topogram AP Chest
Coverage Caudo-cranial: Below diaphragm (include lung bases) – 5cm above shoulder (include lung apices)
Technique - Spiral / helical technique
- Use bone algorithm wt high resolution (kernel B70-80)
3. CT Pulmonary Angiogram
Indication Pulmonary embolism, down to subsegmental level
May complement wt CT venogram for lower limbs (to look for DVT)
Exposure 100kV, 115mAs
Contrast Green line, at antecubital fossa
IV LOCM 70 – 100mls, 5mls/sec
Position Supine, OML ∟ Table
Upper limbs above the head
Topogram AP Chest
Coverage Cranio-caudal: Lung apices (just above aortic arch) – Lung bases(just above diaphragm)
Technique - Spiral / helical technique
- Contrast scanning:
a) Delayed scan - Contrast injection
- Spiral scan after delay of 15sec
b) Bolus tracking - Place ROI at pulmonary trunk
- Contrast injection
- Triggering HU: 100 – 120 HU
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ABDOMEN
1. CT Abdomen-Pelvis
Indication a) Abdominal mass c) Intestinal obstruction
b) Tumour staging d) Altered bowel habit in elderly
Exposure 120kV, 300mAs
Contrast a) Oral contrast: 3% Gastrograffin, 250-300mls x 3doses, 30mins before scanning
2% Barium is an alternative
b) Rectal contrast: 3% Gastrograffin, 100mls
c) IV Contrast: IV LOCM 100mls, 3mls/sec
May require tampon for female
Position Supine, OML ∟ Table
Upper limbs above the head
Topogram AP Abdomen
Coverage If just abdomen Caudo-cranial: Iliac crest – Dome of diaphragm
If abdomen-pelvis Symphysis pubis – Dome of diaphragm
Technique - Spiral / helical technique
- Scan at 60sec delay (porto-venous phase), delayed bladder view at 5mins may be required
- Acquired slice thickness: 1mm (Detector configuration: 0.6mm x 64 per scan)
- Recon slice thickness (for medweb): 10mm
- MPR (multiplanar recon): 1mm slice thickness with 30% overlapping
Window Soft tissue setting: 450 WW / 50 WL
2. CT Colonography
Indication a) Screening for individual at high risk of colon ca
b) Failed / incomplete colonoscopy
c) Patient’s refusal for colonoscopy
Preparation Full bowel preparation
Exposure 80mA (Low dose technique)
Contrast Rectal contrast: Air or CO2
Position Supine & prone
Topogram AP & PA Abdomen
Coverage Dome of diaphragm – Symphysis pubis
Technique - Patient in left lateral position
- Insert Foley’s catheter / rectal tube into the rectum
- Air or CO2 insufflated, IV Buscopan 20mg or IV Glucagon 1mg given during insufflation
- Scan abdomen in supine & prone position
- Recon
a) 2D MPR images
b) 3D endoluminal (fly through) images
Window Soft tissue setting: 450 WW / 50 WL
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5. CT Cholangiography
MR Cholangiography is usually a better option
Indication a) Cholelithiasis
b) Other biliary abnormality: Polyps, congenital abnormalities
c) Traumatic biliary injury
d) Pre-op screening of anatomy
Exposure
Contrast Cholangiographic agent → Opacification of biliary tree
a) IV Meglumineiotroxate 100mls, over 50mins OR
b) IV Iodipamidemeglumine 52% 20mls diluted wt NS 80mls, over 30mins
Position Supine, OML ∟ Table
Upper limbs above the head
Topogram AP Abdomen
Coverage
Technique Scan after 30mins contrast injection
Window Soft tissue setting: 450 WW / 50 WL
6. CT Urogram
Indication a) Investigation for renal colic
b) Assessment of renal calculi / obstructive uropathy
Exposure 120kV, 120mAs
Contrast Plain
Full bladder
Position Supine
Upper limbs above the head
Topogram AP Abdomen
Coverage Caudo-cranial: Symphysis pubis (include bladder) – Top of the kidneys
Technique - Spiral / helical technique
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7. CT IV Urogram
Indication a) Investigation for renal colic
b) Assessment of renal calculi / obstructive uropathy
c) Assessment of renal parenchymal & collecting system
Exposure 120kV, 120mAs
Contrast - Full bladder
- IV LOCM 100mls, 3mls/sec
Position Supine
Upper limbs above the head
Topogram AP Abdomen
Coverage a) Plain Top of the kidneys – Symphysis pubis (include bladder)
b) Nephrographic Only kidneys
c) Delayed kidney & bladder Top of the kidneys – Symphysis pubis (include bladder)
* No cortico-medullary phase
Technique - Spiral / helical technique
- Scan for (a) plain study
- Contrast injection (delayed scan / bolus timing)
- Phases:
b) Nephrographic Delay at 100 – 120sec
c) Delayed bladder Delay at 5mins
8. CT Renal 4 phase
Indication Diagnosis of renal mass
Exposure 120kV, 300mAs
Contrast - Green line, at antecubital fossa
- IV LOCM 100mls, 5mls/sec
Position Supine, OML ∟ Table
Upper limbs above the head
Topogram AP Abdomen
Coverage a) Plain Only kidneys
b) Cortico-medullary phase (Arterial) Only kidneys
c) Nephrographic phase (Venous) Doom of diaphragm – Symphysis pubis
d) Excretory phase (Delayed) Upper border of kidneys – Symphysis pubis
Technique - Spiral / helical technique
- Scan for (a) plain study
- Contrast injection (delayed scan / bolus timing)
- Phases:
b) Cortico-medullary phase (Arterial) Delay at 30sec
c) Nephrographic phase (Venous) Delay at 60sec (Delay 30sec from cortico-medullary phase)
d) Excretory phase (Delayed) Delay at 5mins
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9. CT Adrenal Protocol
Indication Diagnosis of adrenal mass
Suspicious of pheochromocytoma (must correlate wt HPT, VMA level)
Exposure 120kV, 250mAs
Contrast a) Plain (if suspect pheochromocytoma)
b) Contrast
- Oral water
- IV LOCM 100mls, 5mls/sec (not to be given if suspect pheochromocytoma, as it may precipitate HPT crisis !!)
Position Supine, OML ∟ Table
Upper limbs above the head
Topogram AP Abdomen
Coverage Adrenal glands – Bifurcation
Technique - Spiral / helical technique
- Scan for (a) plain study
- Contrast injection (delayed scan / bolus timing)
- Phases: * No arterial phase
b) Porto-venous phase Delay at 60sec
c) Delayed phase Delay at 10mins
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CT Thorax-Abdomen-Pelvis
Indication a) Diagnosis & staging of malignancy
b) Assessment of treatment response
Exposure 120kV, 300mAs
Contrast a) Oral contrast: 3% Gastrograffin, 250-300mls x 3doses, 30mins before scanning
2% Barium is an alternative
b) Rectal contrast: 3% Gastrograffin, 100mls
c) IV Contrast: IV LOCM 100 - 120mls, 3mls/sec
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MUSCULOSKELETAL
1. CTA Lower Limb
Indication a) Lower limb ischaemia
b) AVM of lower limb
c) Vascular injury following trauma of lower limb
Exposure
Contrast - Green line, at antecubital fossa
- IV LOCM 120mls, 5mls/sec
Position Supine
Topogram AP LL
Coverage Cranio-caudal: Iliac crest – Tip of toes
Technique - Spiral / helical technique
- Place ROI at abdominal aorta, level of infrarenal
- Contrast injection
- Triggering HU: 100 – 120 HU
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RESONANCE
IMAGING
(MRI)
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GENERAL PRINCIPLES
A. T1 & T2 weighted images
TR TE
T1 Short (< 500 ms) Short (< 30 ms)
T2 Long (> 1,500 ms) Long (> 80 ms)
Proton spin density (PD) Long Short
B. Signal intensity
T1-weighted T2-weighted PD-weighted
Hyperintense (Bright)
1 Fat Water, CSF Fat, fluid (joint fluid) 1
2 Marrow 2
3 3
4 Intervertebral disc 4
5 Brain (white matter) Brain (grey matter) 5
6 6
7 Liver, pancreas Spleen 7
8 Brain (grey matter) Muscle, hyaline cartilage 8
9 Kidney 9
10 Spleen 10
11 11
12 Brain (white matter) 12
13 Liver 13
14 CSF Fat 14
15 Water, lung Iron in basal ganglia 15
16 Air, cortical bone, flowing blood Air, bone, flowing blood Fibrocartilage 16
Hypointense (Dark)
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D. Summary of MR sequences
1. Saturation recovery sequences a) T1-weighted image
b) T2*-weighted image
c) Proton/spin density-weighted image (PD)
2. Spin echo sequences (SE) a) Dual / Double Spin Echo Sequence
a) T1-w image b) Fast / Turbo Spin Echo Sequence (FSE / TSE): HASTE, RARE
b) T2-w image c) Single-shot FSE Sequence (SSFSE)
c) Proton/spin density-w image (PD)
3. Gradient/Field echo sequences (GRE) a) Spoiled/incoherent GRE: SPGR, T1-TFE & T2-TFE, MEDIC, FLASH, VIBE, LAVA, THRIVE
a) T1-w image b) Steady-state free precession (SSFP)
b) T2*-w image (i) Post-excitation refocused steady-state sequences: T1-FFE, FISP, GRASS
c) Proton/spin density-w image (PD) (ii) Pre-excitation refocused steady-state sequences: T2-FFE, Reverse FISP (PSIF)
d) In-phase & Out-of-phase (iii) Fully refocused / Balanced SSFP sequences: Balanced FFE, True FISP, CISS,
(modification of T1-w 2D GRE) DESS, FIESTA
4. Inversion recovery sequences (IR) a) Short tau inversion recovery (STIR)
b) Fluid attenuation inversion recovery (FLAIR)
c) Turbo inversion recovery magnitude (TIRM)
d) Double inversion recovery (DIR)
5. Echo-planar pulse sequences (EPI) EPI GRE & EPI SE
6. Fat suppression sequences a) Frequency-selective fat suppression (CHESS, Fat sat)
b) Short tau inversion recovery (STIR)
c) Out-of-phase imaging
d) Dixon method
e) Water selective excitation
7. Diffusion weighted sequences a) Diffusion weighted image (DWI)
b) Apparent diffusion coefficient (ADC)
c) Diffusion tensor imaging (DTI)
8. Perfusion weighted imaging
9. Susceptibility weighted imaging (SWI) Magnitude, filtered phase, SWI, MIP SWI
10. Flow sensitive sequences a) MR angiography (MRA): (i) Conventional MRI – Black blood (SE) & Bright blood (GRE)
(ii) Non-contrast enhanced MRA – TOF & phase contrast
(iii) Contrast enhanced TOF MRA
b) MR venography (MRV)
c) CSF flow study
11. MR spectroscopy
12. Functional MRI BOLD imaging
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BRAIN
A. Routine brain
Position - Supine, head first
- Head in head coil, in symmetry position (nose & outer canthus as reference point)
- Centering point: Nasion / Galbella
Scout images - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 230mm2, TR: 7ms, TE: 2.95ms
Planes:
1. Axial - Planes: Parallel to temporal lobe Axial
- Coverage: Vertex – Foramen magnum
- Total slice ≈ 19
- SL: 5mm, FOV: 230mm2
2. Coronal - Planes: Perpendicular to axial plane
(temporal lobe)
- Coverage: From frontal sinus,
to cover the whole brain
- Total slice ≈ 19
- SL: 5mm, FOV: 230mm2
Coronal
3. Sagittal - Planes: Parallel to interhemispheric fissure
- Coverage: Right – Left parietal bone
- Total slice ≈ 19
- SL: 5mm, FOV: 230mm2
4. T1 MPRAGE - Planes: Acquire sagittal images
(Parallel to interhemispheric fissure)
- Coverage: Right – Left parietal bone
- Total slice ≈ 176
- SL: 1mm, FOV: 250mm2
- TR: 1,900ms, TE: 3ms Sagittal
- Post-processing axial, coronal & sagittal
images (SL: 5mm)
5. T2 CISS 3D - Planes: Acquire axial (IAC) images
Parallel to temporal lobe (Coronal image)
Parallel to hard palate (Sagittal image)
- Coverage: Pons & IAC
- Total slice ≈ 64
- SL: 0.5mm, FOV: 200mm2
- TR: 5.78ms, TE: 2.42ms
Sequence
1. T1 TR: 450ms, TE: 9ms - Anatomy scan
2. T2 TR: 5,000ms, TE: 103ms - Pathology scan
3. T2 FLAIR TR: 8,000ms, TE: 106ms, TI: 2,500ms - Better visualization of periventricular lesion & multiple sclerosis
4. T1 med IR TR: 8,600ms, TE: 66ms, TI: 400ms - Detect cortical dysplasia & migrational abN (epilepsy)
4. T2 FLASH - TR: 800ms, TE: 26ms - Detect haemorrhage (Ferritin, hemosiderin) & calcification
GRE (Hemo)
5. DWI / ADC TR: 3,300ms, TE: 97ms - Detect restricted diffusion
4 sets of images: b=0, b=500, b=1,000, ADC
Flow sequence MRA-TOF
1. MRA-TOF - Planes: Parallel to BOS
COW - Coverage: COW & basilar artery
- Total slice ≈ 132
- SL: 0.6mm, FOV: 180mm2
- TR: 24ms, TE: 7ms
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B. Common Protocols
Indications Protocol
1. Stroke Axial: T1, T2, T2 FLASH - GRE or SWI, DWI/ADC
Sagittal: T1, T1 MPRAGE
Coronal: T2 FLAIR
MRA-TOF COW & Neck ± Gadolinium
MRV-phase contrast (if infarcts are peripheral or haemorrhagic, TRO venous sinus thrombosis)
2. ICB Axial: T1, T1 (CE), T2, T2 FLASH - GRE or SWI, DWI/ADC
Sagittal: T1, T1 (CE)
Coronal: T1 (CE), T2 FLAIR
MRA-TOF COW ± Gadolinium (if vascular malformation)
MRV-phase contrast (if infarcts are peripheral or haemorrhagic, TRO venous sinus thrombosis)
3. Vasculitis Axial: T1, T1 (CE), T2, T2 FLASH - GRE or SWI, DWI/ADC
Sagittal: T1 MPRAGE
Coronal: T1 (CE)
MRA-TOF COW ± Gadolinium
4. Dementia & Axial: T1, T2, T2 FLASH – GRE, DWI/ADC
neuro-psychiatric problem Coronal: T2 FLAIR,
Sagittal: T1 MPRAGE
MRA-TOF COW
5. Demyelination (MS) Axial: T1 ± T1 (CE), T2, T2 FLAIR
Sagittal: T1, T2, T2 FLAIR
Coronal: ± T1 (CE), T2
Spinal cord
T2 in all 3 planes: Mainstay for demyelinating lesions
FLAIR: To assess periventricular lesions
FLAIR sagittal: Best shows callaso-septal lesions
Spinal cord: TRO cord involvement
6. Epilepsy 1. TRO SOL or cortical dysplasia
2. Assess temporal lobes & hippocampus (esp in partial seizure)
Axial (whole brain): T2
Coronal (whole brain): T2, T2 FLAIR
(only temporal lobes): Medium T1 IR
Sagittal: T1 MPRAGE
T2 FLAIR: to look for small cortical epileptogenic foci & abN signal in the mesial temporal sclerosis
Medium T1 IR: To look for cortical dysplasia & migrational abN
7. Tumour & Infection 1. Differentiate neoplastic from non-neoplastic lesion (Eg. Infection)
2. Grading of tumour
3. Guiding for biopsy or surgery
4. Spinal cord screening TRO drop metastasis
(ependymoma, medulloblastoma, hemangioblastoma, choroid plexus tumour)
Axial: T1, T1 (CE), T2, T2 FLASH - GRE or SWI, DWI / ADC
Coronal: T1 (CE), T2 FLAIR
Sagittal: T1 MPRAGE (CE)
Spectroscopy for mass
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T1 T2 T2 FLAIR GRE
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C. Sella
Indications 1. Pituitary lesions (adenoma, macroadenoma, microadenoma)
2. Endocrine abnormalities (hypopituitarism, prolactinoma, Cushing’s ds)
Planes
1. Axial - Planes: Parallel to temporal lobe
(Whole brain) - Coverage: Vertex – Foramen magnum Sagittal Coronal
- Total slice ≈ 19
- SL: 5mm, FOV: 230mm2
2. Sagittal - Planes: Planned on axial image at cavernous sinus
(Pit fossa) Parallel to midline
- Coverage: The whole cavernous sinus
- Total slice ≈ 11
- SL: 3mm, FOV: 200mm2
3. Coronal - Planes: Planned on mid-sagittal image
(Pit fossa) Perpendicular to sellar floor (or pituitary stalk)
- Coverage: Orbital apex – Petrous apex
- Total slice ≈ 11 (5 for dynamic study)
- SL: 3mm, FOV: 200mm2
Protocol All cases except microadenoma: Pituitary microadenoma:
Axial (whole brain): T1, T1 (CE), T2, T2 FLAIR Axial (whole brain): T1, T1 (CE), T2, T2 FLAIR
Sagittal (pit fossa): T1, T1 (CE), T2, T1 MPRAGE CE) Sagittal (pit fossa): T1, T1 (CE), T2, T1 MPRAGE CE)
Coronal (pit fossa): T1, T1 (CE), T2 Coronal (pit fossa): T1, T1 (CE), T2, T1 (CE) dynamic study
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T2 CISS 3D axial
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F. Orbit
Indications 1. Eye symptoms (suspected intra-orbital or visual pathway lesions, diplopia)
2. Infection & Inflammation (orbital cellulitis/abscess, optic neuritis)
3. Tumour (retinoblastoma, orbital pseudotumour)
4. Thyroid eye disease
5. Trauma
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 230mm2, TR: 7ms, TE: 2.95ms
Planes
1. Axial - Planes: Parallel to temporal lobe Axial (orbit)
(Whole brain) - Coverage: Vertex – Foramen magnum
- Total slice ≈ 19
- SL: 5mm, FOV: 230mm2
2. Axial - Planes: Parallel to optic nerve / temporal lobe
(Orbit) - Coverage: Orbital roof – Orbital floor
- Total slice ≈ 19
- SL: 3mm, FOV: 220mm2
3. Coronal - Planes: Perpendicular to optic nerve / temporal lobe
(Orbit) - Coverage: Eye lid – To include cavernous sinus
- Total slice ≈ 21
- SL: 3mm, FOV: 220mm2 Coronal (orbit)
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Sagittal
Sequence:
1. T1 TR: 450ms, TE: 17ms
2. T2 TR: 5,000ms, TE: 110ms
Protocol Axial: T1, T1 fat sat, T1 fat sat (CE), T2 fat sat
Coronal: T1, T1 fat sat, T1 fat sat (CE)
Sagittal: T1 MPRAGE
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B. Temporo-Mandibular Joint
Indications 1. Pain (TMJ headache, pain in the jaw, ear area, tooth, neck, shoulder)
2. Jaw movement (Irregular movement, difficult movement, clicking sounds during jaw movement)
Preparation - Practice open/close mouth technique wt patient (may need to fashion bite block, to maintain open mouth position)
- Patient has to chew gum intensely for at least 20mins
- Inject IV Gadolinium 0.1 – 0.2 mmol/kg 30mins before scan
Position - Supine, head first
- Use TMJ double coil, in symmetry position (nasal bridge & outer canthus as reference point)
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 230mm2, TR: 7ms, TE: 2.95ms
Planes
1. Coronal - Scout: Axial image Coronal
- Planes: Across each mandibular condyle
(≈20o off horizontal plane)
- SL: 2mm, FOV: 120mm2
Sagittal
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SPINE
Indications:
1. Cord compression, radiculopathy/myelopathy, cauda equina synd 5. Demyelinating disease (MS), syringomyelia
2. Infection / inflammation 6. Scoliosis (MR whole spine)
3. Tumour, drop metastases of CNS tumour 7. Previous spinal surgery
4. Trauma
Bone marrow - Yellow marrow: Bright on T1, isointense on T2 (contains fat)
- Red marrow: Dark on T1, bright on T2 (contains hematopoietic tissue)
- As a child grow, red marrow converts gradually into yellow marrow
Intervertebral disc - Annulus fibrosus: Dark in all sequence (low mobile proton density)
- Nucleus pulposus: Dark on T1, bright on T2 (high water content)
- Internuclear cleft: Central dark horizontal area in nucleus pulposus on T2 (in adult > 30yrs)
Spinal cord Grey on both T1 & T2
A. Cervical Spine
Position - Supine, head first, arms by each side
- Use head & neck coils, in symmetry position (nasal bridge & outer canthus as reference point)
- Centering point: Thyroid cartilage
Scout image - Planes: Sagittal, axial, coronal (3 slices in each plane)
- SL: 8mm, FOV: 300mm2, TR: 7ms, TE: 2.87ms
Planes: Sagittal
1. Sagittal - Scout: Coronal neck & upper chest
- Planes: Straight sagittal (Parallel to spine)
- Coverage:
Superior Craniovertebral junction
Inferior Upper thoracic vertebra
Lateral Transverse process on both sides
- Total slice ≈ 15
- SL: 3mm, FOV: 250mm2
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B. Thoracic Spine
Position - Supine, head first, arms by each side
- Use head, neck & spine coils, in symmetry position (mid-sagittal line as reference point)
- Centering point: Thyroid cartilage
Scout image - 2 sets of scout images: Cervico-thoracic & Thoraco-lumbar
- Planes: Sagittal, axial, coronal (3 slices in each plane)
- SL: 8mm, FOV: 500mm2, TR: 7ms, TE: 2.87ms
Planes:
1. Sagittal - Scout: Coronal cervico-thoracic region (upper thorax) Sagittal
Coronal thoraco-lumbar region (lower thorax)
- Planes: Straight sagittal (Parallel to spine)
- Coverage:
Upper thorax:
Superior Craniovertebral junction
Inferior Whole thoracic vertebrae
Lateral Transverse process on both sides
Lower thorax:
Superior C7/T1 junction
Inferior Sacral vertebra
Lateral Transverse process on both sides
- Total slice ≈ 19 (each)
- SL: 3mm, FOV: 400mm2
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C. Lumbosacral Spine
Position - Supine, head first, arms by each side
- Use head, neck & spine coils, in symmetry position (mid-sagittal line as reference point)
- Centering point: Thyroid cartilage
Scout image - Planes: Sagittal, axial, coronal (3 slices in each plane)
- SL: 8mm, FOV: 500mm2, TR: 7ms, TE: 2.87ms
Planes: Sagittal
1. Sagittal - Scout: Coronal thoraco-lumbar region
- Planes: Straight sagittal (Parallel to spine)
- Coverage:
Superior T12/L1 junction
Inferior Coccyx vertebra
Lateral Transverse process on both sides
- Total slice ≈ 19 (each)
- SL: 3mm, FOV: 280mm2
T1 T2 T2 STIR
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D. Whole Spine
Position - Supine, head first, arms by each side
- Use head, neck & spine coils, in symmetry position (mid-sagittal line as reference point)
- Centering point: Thyroid cartilage
Scout image - 2 sets of scout images: Cervico-thoracic & Thoraco-lumbar
- Planes: Sagittal, axial, coronal (3 slices in each plane)
- SL: 8mm, FOV: 500mm2, TR: 7ms, TE: 2.87ms
Planes: Sagittal
1. Sagittal - Scout: Coronal spine
- Planes: Straight sagittal (Parallel to spine)
- Coverage:
1st stack C1 – T6
2nd stack T5 – S4
Lateral Transverse process on both sides
- Total slice ≈ 19 (each)
- SL: 3mm, FOV: 400mm2
Axial
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CARDIOVASCULAR SYSTEM
A. MRI Cardiac
Evaluation 1. Anatomy 2. Function
a) Heart a) Myocardial mass, wall motion
b) Great vessels b) Stroke volume, ejection fraction
c) Coronary arteries c) Valvular function
d) Myocardial perfusion & viability
Indications 1. Congenital heart disease (ASD, VSD, TGA, truncus arteriosus)
2. Valvular heart disease
3. Cardiomyopathies (hypertrophic CM, restrictive CM v/s restrictive pericarditis, infiltrative CM)
4. Coronary artery disease
a) Assess ventricular function
b) Assess myocardial perfusion & viability
5. Cardiac mass (myocardial & pericardial)
Preparation - Refrain from stimulus (caffeine) on the examination day
- NBM 4hrs
- IV line
Position - Head first
- Use body coil (dedicated cardiac phase array coil is preferred)
Technique 1. ECG gating
- To acquire images in a particular phase of cardiac cycle in every cardiac cycle
→ To avoid cardiac motion artifact
→ To get ‘motion-free’ images of the heart
- Usually R wave is used to trigger acquisition, after some delay following R wave, in the diastolic phase
2. Respiratory gating:
a) Navigator → Allow free breathing
b) Breath hold technique
Scout image Axial, sagittal & coronal section
Planes 1. 2-chamber view (Vertical long-axis)
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3. Short-axis plane
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ABDOMEN
A. Upper Abdomen
Indications Abnormality in the upper abdomen
Position - Supine, head first, arms by each side
- Use body coil (upper abdomen: nipple – iliac crest), in symmetry position (mid-sagittal line as reference point)
- Centering point: Lower costal margin
- Give IV Buscopan 10mg / Glucagon 0.25mg
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 300mm2, TR: 7ms, TE: 2.87ms
Planes:
1. Axial - Scout: Mid-coronal image Axial
- Planes: Perpendicular to coronal plane
- Coverage: Liver dome – Aortic bifurcation
- SL: 8mm, FOV: 360 – 400mm2
Coronal
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Protocol Axial: T1 in-phase & out-of-phase, T1 fat sat (CE), T2, T2 fat sat, DWI/ADC
Dynamic study:
1. Pre-contrast Baseline
2. Arterial phase Immediate after contrast injection
3. Portal venous phase 45sec after contrast injection
4. Delayed phase 5mins after contrast injection
1. Technique
a) Pulse sequences (i) T1 spoiled GRE (iii) T1 GRE fat-supp volume acquisition
(ii) Magnetization-prepared T1 GRE (iv) T2 FSE / TSE
b) In-phase & out-of-phase - Fat in tissue which contains fat & water → Appears darker (on OP image)
Tissue with only fat or only water → Appears similar (on both IP & OP image)
- Best in assessing fatty liver
c) Fat suppression & STIR - ↓ Motion artifacts from subcutaneous & intra-abdominal fat
- ↑ Dynamic range of the image
- Better delineation of fluid-containing structures
- Improves signal-to-noise & contrast-to-noise ratio of focal liver lesions
d) Very heavily T2w Show water content in bile ducts, cysts & some focal lesions
sequences (i) GRE breath-hold sequences (FISP)
(ii) Breath-hold very FSE (HASTE)
(iii) Non-breath-hold respiratory gated sequences used for MRCP
2. Contrast studies:
a) Gadolinium
(i) T1 spoiled GRE sequences - Arterial phase: Sensitive to liver metastasis, HCC
- Portal phase: Sensitive to hypovascular malignancies
- Equilibrium phase: Sensitive to cholangioCa, slow-flow haemangiomas
(ii) T2 FSE - Sensitive to HCC, neuroendocrine tumours
b) Reticuloendothelial cell agents - Taken up by RE or Kuppfer cells → ↓ T2 intense
(SPIO) - Not taken up by malignant lesions → ↑ T2 intense
c) Hepato-biliary agents: - Taken up by normal hepatocytes & excreted into bile → ↑ T1 Intensity
Gd-BOPTA (Multihance) - Not taken by metastatic lesions → ↓ T1 Intensity
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T1 T1 fat sat T2
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C. MR Cholangio-Pancreaticography (MRCP)
Indications 1. Obstructive jaundice
a) Biliary calculus (choledocholithiasis)
b) Malignancy (cholangioCa, pancreatic head Ca)
2. Cystic disease of bile duct (choledochal cyst, choledochocele, Caroli’s disease)
3. Congenital anomalies (low cystic duct insertion, medial cystic duct insertion, parallel course of cystic & hepatic ducts)
4. Chronic pancreatitis
5. Sclerosing cholangitis
6. Prior to ERCP / PTC
7. Post-surgical complications
Contrast No contrast needed
Preparation NBM 4-8hrs → Distend biliary tract, ↓ fluid in gastric antrum & duodenum
Position - Supine, head first, arms by each side
- Use body coil (upper abdomen: nipple – iliac crest), in symmetry position (mid-sagittal line as reference point)
- Centering point: Lower costal margin
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 300mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Coronal image
- Planes: Perpendicular to coronal plane
- Coverage: Biliary system (diaphragm – C-loop duodenum)
- SL: 3mm, FOV: 400mm2
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D. Pancreas
Indications 1. Pancreatic tumours (adenoCa, cystic neoplasm, islet cell tumour)
2. Same as CT pancreatic protocol * CT is preferred d/t availability & cost
Position - Supine, head first, arms by each side
- Use body coil, in symmetry position (mid-sagittal line as reference point)
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 300mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Mid-coronal image
- Planes: Perpendicular to coronal plane
- Coverage: Whole pancreas (superior – inferior)
- SL: 5mm, FOV: 380-400mm2
Paracoronal
T1 T2 T2 fat sat
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Coronal
Protocol
1st scan: Coronal: T2
Pre-buscopan scanning
(Give 1st dose IV Buscopan 10mg / Glucagon 0.25mg)
2nd scan: Axial: T1 fat sat, T2
Post-buscopan scanning Coronal: T1 fat sat, T2
(Give 2nd dose IV Buscopan 10mg / Glucagon 0.25mg, together wt IV Gadolinium)
3rd scan: Axial: DWI/ADC
Post-contrast scanning Coronal: 3D T1 fat sat (VIBE,THRIVE,LAVA), T2
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T1 axial T2 axial
T1 coronal T2 coronal
DWI ADC
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I. Pelvis - Rectum
Indications 1. Local staging of rectal ca
2. Suspected perianal fistula
Contrast Air within bowel is a natural contrast agent
Additional CM is usually not needed
Position - Supine, head first, arms by each side
- Use body coil (upper border at iliac crest), in symmetry position (mid-sagittal line as reference point)
- Centering point: Centre of the coil
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Mid-sagittal image
- Planes: Perpendicular to rectal axis
- Coverage: Iliac crest (sup) – Anus (inf)
- Total slice ≈ 25
- SL: 3mm, FOV: 350mm2
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GENITO-URINARY TRACT
A. Kidney
Indications 1. Inflammation/infection (Xanthogranulomatous pyelonephritis)
2. Benign lesion (Cyst, angiomyolipoma, oncocytoma)
3. Malignant lesion (RCC, TCC)
Position - Supine, head first, arms by each side
- Use body coil, in symmetry position (mid-sagittal line as reference point)
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 300mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Coronal image
- Planes: Perpendicular to coronal plane
- Coverage: Whole kidney (superior – inferior)
- SL: 5mm, FOV: 380-400mm2
T1 T1 fat sat
T2 T2 fat sat
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B. MR Urography (MRU)
Indications 1. Renal pathology 2. Local staging of bladder ca
a) Renal mass / scarring 3. Potential renal transplant donor (+ MRA renal)
b) Congenital renal anomalies
c) Obstructive uropathy
- Not d/t calculi
- Patient wt poor renal function
d) Screening for von Hippel-Lindau disease
Contrast IV Gadolinium 0.1 mmol/kg
± IV Lasix 0.3 mg/kg (5-10mg in adult)
Preparation - Keep NBM 4hrs prior to procedure
- KIV sedation (children)
- Insert branulla, hydrate wt 1ʘ NS 30mins prior to procedure
- Empty bladder, insert CBD if patient sedated (children)
* In-phase & out-of-phase T1 GRE → To identify adrenal lesions / lipid within angiomyolipoma / renal clear cell ca
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C. MRA Renal
Indications 1. Renal artery anomalies (aneurysm, AVM, dissection, stenosis)
2. Potential renal transplant donor (+ MRU)
Contrast Pump injector: 30mls Gadolinium + 60mls NS
IV Gadolinium 0.1 mmol/kg, 2mls/sec
Preparation - Insert branulla (at least 21G – Pink) at the antecubital fossa
- Supine, head first, arms on each side of the body
- Use body coil
Position - Supine, head first, arms by each side
- Use body coil (xiphoid process – ASIS), in symmetry position (mid-sagittal line as reference point)
- Centering point: Centre of the coil
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
Kidneys are in the middle of the frame
Both common iliac arteries (down to the bifurcation) are included
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.87ms
Planes:
Coronal - Scout: Axial & sagittal images
- Planes: Parallel to midline along Rt – Lt kidneys
Parallel to abdominal aorta
- Coverage: Both kidneys anterior – posterior
- SL: 3mm, FOV: 350mm2
Protocol 1. Pre-contrast renal scan: T2 coronal (at the level of renal hila)
2. MRA-phase contrast renal
Set ROI at abdominal aorta, for contrast bolus tracking
Contrast infusion via pump injector
3. Post-contrast MRA: T1 FLASH-3D axial
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D. Adrenal Glands
Indications Adrenal mass: Adenoma vs Metastasis, suspected pheochromocytoma
Position - Supine, head first, arms by each side
- Use body coil (upper border at iliac crest), in symmetry position (mid-sagittal line as reference point)
- Centering point: Centre of the coil
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Coronal image
- Planes: Perpendicular to coronal plane
- SL: 5mm, FOV: 380-400mm2
Coronal
T1 axial T2 axial
T1 coronal T2 coronal
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E. Pelvis - Male
Indications 1. Prostate gland: Local staging of prostate carcinoma / sarcoma
2. Testis & scrotum: Primary tumour, intra/extra testicular abN, undescended testis
Position - Supine, head first, arms by each side
- Use body coil (upper border at iliac crest), in symmetry position (mid-sagittal line as reference point)
- Centering point: Centre of the coil
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Mid-sagittal image
- Planes: Perpendicular to prostate gland
- Coverage: Iliac crest – Symphysis pubis
- Total slice ≈ 25
- SL: 3mm, FOV: 350mm2
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F. Pelvis - Female
Indications 1. Vagina: Congenital anomalies, tumour
2. Uterus: Congenital anomalies, tumour (leiomyoma, carcinoma, sarcoma, gest trophoblastic tumour), adenomyosis
Cervix: Tumour
3. Ovary: Ovarian torsion, cysts, endometrioma, tumour (carcinoma, teratoma)
Position - Supine, head first, arms by each side
- Use body coil (upper border at iliac crest), in symmetry position (mid-sagittal line as reference point)
- Centering point: Centre of the coil
Scout image - Planes: Axial, sagittal, coronal (3 slices in each plane)
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Mid-sagittal image
- Planes: Perpendicular to uterine axis
- Coverage: Iliac crest – Symphysis pubis
- Total slice ≈ 25
- SL: 3mm, FOV: 350mm2
Coronal
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MUSCULOSKELETAL SYSTEM
Indications:
1. Injuries (Sport, trauma)
2. Degenerative disorders
3. Infection / inflammation
4. Tumour
Contrast media
a) Direct arthrography Intra-articular Gadolinium-DTPA To assess cartilage, capsule, labrum, meniscus, ligament
b) Indirect arthrography IV Gadolinium-DTPA To assess:
(i) Synovial disease (RA)
(ii) Infections
(iii) Tumours
(iv) AVN (Perthe’s disease, scaphoid fracture)
(v) Postop spine (to differentiate disc herniation from scar tissue)
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A. Shoulder
Indications 1. Injuries (Sport, trauma):
- Shoulder pain/fracture/dislocation
- Muscle (rotator cuff, biceps), labrum, ligament (glenohumeral), bursa (subacromial bursitis)
- Impingement syndrome, coracoclavicular & acromioclavicular separations
2. Degenerative disorders
3. Infection / inflammation
4. Tumour
MR Arthrogrm Shoulder joint instability → To assess glenohumeral ligaments & labrum
Position - Supine, head first, arms by each side (in neutral rotation)
- Use shoulder coil, in symmetry position (mid-sagittal line as reference point)
- Centering point: Head of humerus
Scout image - Planes: Axial, coronal (oblique), sagittal (oblique) – 3 slices in each plane
- SL: 6mm, FOV: 280mm2, TR: 6.4ms, TE: 2.6ms
Planes: Axial
1. Axial - Scout: Coronal oblique image
- Planes: Perpendicular to glenoid
- Coverage: Top of AC joint – Axillary recess
- Total slice ≈ 19
- SL: 3mm, FOV: 160mm2
Sequence:
1. T1 TR: 400ms, TE: 9ms
2. T2 TR: 2,400ms, TE: 79ms
3. PD TR: 2,400ms, TE: 24ms
4. STIR TR: 2,950ms, TE: 28ms, TI: 160ms
Protocol:
1. Usual MRI Axial: T1, T2, PD, STIR
Coronal oblique: T1, T2, PD, STIR, T2 DESS 3D
Sagittal oblique: T1, T2, PD, STIR
± Post-gado: T1 fat sat for axial, coronal oblique & sagittal oblique
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B. Elbow
Indications 1. Injuries (Sport, trauma):
- Fractures (supracondyle, epicondyle, radial head) & dislocation (posterior)
- Lateral epicondylitis (tennis elbow), medial epicondylitis (golfer's elbow)
- AVN of radial head, biceps tendon injury, osteochondral injury, nerve injury
2. Degenerative disorders
3. Infection / inflammation
4. Tumour
Scout image - Supine, head first, arms by each side (in neural rotation)
- Use flex small coil, off centre (elbow as close to centre of gantry as possible)
- Centering point: Elbow joint
Position - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 6mm, FOV: 250mm2, TR: 8.2ms, TE: 3.5ms
Planes: Axial
1. Axial - Scout: Coronal image (both epicondyles)
- Planes: Parallel to epicondyles
- Coverage: Lower ⅓ humerus – Upper ⅓ rad/ulna
- Total slice ≈ 23
- SL: 3mm, FOV: 120mm2
Sagittal
Sequence:
1. T1 TR: 450ms, TE: 7ms
2. T2 TR: 3,000ms, TE: 76ms
3. PD TR: 2,000ms, TE: 33ms
4. STIR TR: 3,200ms, TE: 76ms, TI: 150ms
Protocol Axial: T1, T2
Coronal: T1, T2, STIR
Sagittal: T2, PD
± Post-gado: T1 fat sat for axial, coronal oblique & sagittal oblique
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C. Wrist
Indications 1. Injuries (Sport, trauma):
- Carpal tunnel syndrome
- Tendon (flexor & extensor tenosynovitis), ligament, Triangular fibrocartilage complex (TFCC)
2. Degenerative disorders
3. Infection / inflammation
4. Tumour
Position - Supine, head first, arms by each side (in lateral rotation)
- Use flex small coil, off centre (wrist as close to centre of gantry as possible)
- Centering point: Wrist joint
Scout image - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 6mm, FOV: 250mm2, TR: 8.2ms, TE: 3.5ms
Planes:
1. Axial - Scout: Coronal image (radial & ulnar styloids) Axial
- Planes: Parallel to line joining radial-ulnar styloids
- Coverage: Base of MCBs – Distal radius/ulna
- Total slice ≈ 19
- SL: 3mm, FOV: 120mm2
3. Sagittal - Scout: Axial (Distal row of carpals) & & coronal Coronal
- Planes: Perpendicular to axial & coronal
- Coverage: Base of 1st – 5th MCBs
- Total slice ≈ 15
- SL: 3mm, FOV: 120mm2
Sequence:
1. T1 TR: 450ms, TE: 7ms
2. T2 TR: 3,000ms, TE: 76ms
3. PD TR: 3,500ms, TE: 24ms
4. STIR TR: 3,200ms, TE: 76ms, TI: 150ms
Protocol Axial: T1, T2
Coronal: T1, T2, PD, STIR, T2 DESS 3D
Sagittal: PD fat sat
± Post-gado: T1 fat sat for axial, coronal & sagittal
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D. Hip
Indications 1. Injuries (Sport, trauma): Occult fracture, AVN of femoral head
2. Degenerative disorders
3. Infection / inflammation: Septic arthritis, OM, synovial osteochondromatosis
4. Tumour
Position - Supine, head first, both legs straight (in internal rotation 10o)
- Use body coil (upper border at iliac crest), in symmetry position (both ASIS equidistant from the couch)
- Centering point: Midpoint btw ASIS – Symphysis pubis
Scout image - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.6ms
Planes:
1. Coronal - Scout: Axial image (both femoral heads) Coronal
- Planes: Parallel to line joining both femoral heads
- Coverage: Symphysis pubis – Sacrum
- Total slice ≈ 23
- SL: 3mm, FOV: 350mm2
Sequence:
1. T1 TR: 450ms, TE: 9ms
2. T2 TR: 3,500ms, TE: 91ms
3. PD TR: 3,500ms, TE: 26ms
4. STIR TR: 3,200ms, TE: 15ms, TI: 160ms
Protocol Coronal: T1, T2, PD, STIR
Axial: T2 fat sat, PD fat sat
± Post-gado: T1 fat sat for axial & coronal
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E. Knee
Indications 1. Injuries (Sport, trauma):
- Marrow (AVN, marrow edema syndromes, stress fractures)
- Muscle and tendon (extensor mechanism abN, strains, tears, tendonitis, tendonopathy)
- Osteochondral & articular cartilage (infractions, osteochondral fractures, osteochondritis)
- Loose bodies (chondral, osteochondral, osseous)
- Meniscus (tears, discoid menisci, cysts)
- Ligament (cruciate, collateral, retinaculum)
- Synovial based disorders (synovitis, bursitis, popliteal cysts)
2. Degenerative disorders
3. Infection / inflammation
4. Tumour
Position - Supine, head/feet first, both legs straight (knee in 30o flexion)
- Use knee coil
- Centering point: Patellar apex
Scout image - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 6mm, FOV: 250mm2, TR: 8ms, TE: 3.5ms
Planes:
1. Axial - Scout: Mid-coronal & mid-sagittal images Axial
- Planes: Parallel to line joining inferior surface of
medial-lateral femoral condyles
- Coverage: Just above patella – Patellar tendon insertion
- Total slice ≈ 23
- SL: 3mm, FOV: 160mm2
Sequence:
1. T1 TR: 450ms, TE: 13ms
2. T2 TR: 3,000ms, TE: 96ms
3. PD TR: 3,000ms, TE: 24ms
Protocol Axial: PD fat sat
Coronal: PD fat sat
Sagittal: T1, T2, PD, T2 DESS 3D
± Post-gado: T1 fat sat for axial, coronal & sagittal
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F. Ankle
Indications 1. Injuries (Sport, trauma)
2. Degenerative disorders
3. Infection / inflammation
4. Tumour
Position - Supine, feet first, both legs straight (ankle in neutral position)
- Use flex small coil, off centre (wrist as close to centre of gantry as possible)
- Centering point: Ankle joint
Scout image - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 6mm, FOV: 250mm2, TR: 8ms, TE: 3.5ms
Planes:
1. Axial - Scout: Mid-sagittal image Axial
- Planes: Parallel to calcaneal axis
- Coverage: Distal tibia – Bottom of calcaneum
- Total slice ≈ 19
- SL: 3mm, FOV: 150mm2
Sagittal
Sequence:
1. T1 TR: 600ms, TE: 15ms
2. T2 TR: 3,000ms, TE: 74ms
3. PD TR: 3,000ms, TE: 32ms
4. STIR TR: 4,760ms, TE: 31ms, TI: 160ms
Protocol Axial: T2, PD
Coronal: T1, PD fat sat
Sagittal: T1, STIR
± Post-gado: T1 fat sat for axial, coronal & sagittal
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G. Sacro-iliac Joint
Indications Sacroiliitis
Position - Supine, head first, arms by each side
- Use body coil (upper border at iliac crest), in symmetry position (both ASIS equidistant from the couch)
- Centering point: Midpoint btw ASIS – Symphysis pubis
Scout image - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 8mm, FOV: 400mm2, TR: 7ms, TE: 2.6ms
Planes:
1. Axial - Scout: Mid-sagittal (sacrum) Axial
- Planes: Perpendicular to sacrum
- Coverage: Whole sacrum
- Total slice ≈ 21
- SL: 3mm, FOV: 300mm2
Sequence:
1. T1 TR: 450ms, TE: 9ms
2. T2 TR: 3,500ms, TE: 76ms
3. PD TR: 3,500ms, TE: 39ms
4. STIR TR: 3,500ms, TE: 39ms, TI: 130ms
Protocol Axial: T1, T2, PD
Coronal: T1, T1 fat sat, STIR
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H. Brachial Plexus
Indications 1. Injuries (Sport, trauma)
2. Degenerative disorders
3. Infection / inflammation (acute neuritis)
4. Tumour
Position - Supine, head first, arms by each side
- Use head, neck & body coils, in symmetry position (nasal bridge & outer canthus as reference point)
- Centering point: Thyroid cartilage
Scout image - Planes: Axial, coronal, sagittal (3 slices in each plane)
- SL: 8mm, FOV: 300mm2, TR: 7ms, TE: 2.87ms
Planes: Axial
1. Axial - Scout: Mid-sagittal & coronal (spine)
- Planes: Perpendicular to cervical spine
- Coverage: C4 – T5 (to cover axilla)
- Total slice ≈ 39
- SL: 3mm, FOV: 250mm2
2. Sagittal - Scout: Coronal (neck & upper chest)
- Planes: Straight sagittal (Parallel to spine)
- Coverage: C4 – T5, to include both axillae
- Total slice ≈ 29
- SL: 3mm, FOV: 350mm2 Sagittal
3. Coronal - Scout: Mid-sagittal & axial
- Planes: Parallel to cervical spine
- Coverage:
Anterior Clavicle
Posterior Spinous process
- Total slice ≈ 23
- SL: 3mm, FOV: 350mm2
Coronal
4. CISS 3D - Acquire coronal images
- Scout: Mid-sagittal & axial
- Planes: Parallel to cervical spine
- Coverage:
Anterior Clavicle
Posterior Spinous process
- Total slice ≈ 88
- SL: 1mm, FOV: 350mm2
- TR: 6ms, TE: 3ms
Sequence:
1. T1 TR: 450ms, TE: 8.6ms
2. T2 TR: 6,000ms, TE: 80ms
3. PD TR: 6,000ms, TE: 30ms
4. STIR TR: 5,000ms, TE: 23ms, TI: 160ms
Protocol Axial: T2 fat sat, PD fat sat
Sagittal: T1, STIR
Coronal: T1, CISS 3D
T1 axial T2 sagittal T2 STIR coronal
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Protocol 1. Small round blue cell tumours: T1 out-of-phase, T2, STIR, ± DWI/ADC
(only coronal) 2. Neurofibromatosis: STIR
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MEDICINE
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GENERAL PRICIPLES
1. Nuclear medicine imaging
- Imaging modalities that detect ɣ-rays (via gamma camera)
- produced by radiopharmaceutical agents, administered into the body
c) Lungs
(i) Ventilation scan 99mTc-technegas
e) Renal
(i) Dynamic 99mTc-diethylene triaminepentacetic acid (DTPA) / 99mTc-mercaptoacetyltriglycine (MAG-3)
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BRAIN
A. Positron Emission Tomography, PET scan
Indications Indications: Contraindications:
1. Brain tumour 1. Recent chemotherapy (minimum interval 2-3 wks)
2. Epilepsy 2. Recent radiotherapy (minimum interval 8-12 wks)
3. Dementia 3. Poorly controlled DM (DXT < 8.5 mmolL)
4. CIx for ionizing radiation
Radiopharma 1. Fluorine-18 fluorodeoxyglucose (18FDG) OR
- Max dose: 400 MBq (10 mSv ED)
2. L-[methyl- 11C] methionine ([11C] MET) OR
3. 3’-deoxy-3’-[18F] fluorothymidine ([18F] FLT)
Preparation NBM for 6hrs
Ensure good glycemic control
Technique - Administer 18FDG
- Minimize movement & activity to ↓ muscle uptake
- Acquire image at 1hr post-injection
Aftercare Ensure good glycemic control
Complication None
C. Radionuclide Cisternography
Indications Indications: Contraindication: Relative
1. Normal pressure hydrocephalus 1. Meningitis
2. VP shunt dysfunction 2. ↑ ICP
3. Occult CSF rhinorrhea / otorrhea 3. CIx for ionizing radiation
4. Porencephalic / leptomeningeal / posterior fossa cysts
Radiopharma 1. 99mTc-DTPA 2. 111Indium-DTPA
- Dose: 4 – 10 mCi - Dose: 250 – 500 μCi
- Easily available, lower radiation, better resolution - Suitable for intermittent CSF leak
- Suitable to detect fast profuse CSF leak
Preparation NBM for 6hrs
Insert nasal / ear pledgets to improve detection
Technique - Inject intrathecal radionuclide, via lumbar puncture
- Image acquisition: 2hrs, 6hrs, 24hrs after injection
Analysis Adult: Children: More rapid
(Normal findings) 1 – 3 hrs Activity seen in basal cisterns 15 – 30 mins Activity seen in basal cisterns
3 – 6 hrs Sylvian fissure & IHF 12hrs Surround the brain
> 24 hrs Surrounds the brain
No activity normally seen in ventricles
4 hrs post injection: 24 hrs post injection:
Aftercare None
Complication None
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Aftercare None
Complication None
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RESPIRATORY SYSTEM
A. Radionuclide Lung Ventilation / Perfusion Imaging (V/Q Scan)
Indications Indications: Contraindications: Relative
1. Pulm embolism (CTPA is still the gold standard) 1. Rt-to-Lt shunt(Risk of cerebral emboli)
2. Congenital heart / pulm disease → However, perfusion scan can also be used for its assessment
3. Quantification of lung performance, 2. Severe pulm HPT
before/after lung transplant / volume reduction surgery 3. CIx for ionizing radiation
4. Assessment of Rt-to-Lt shunt
Aftercare None
Complication Respiratory failure following MAA injection
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GASTRO-INTESTINAL TRACT
A. Meckel’s Diverticulum Scan
Indications Indications: Contraindications:
To detect Meckel’s diverticulum, 1. Recent barium study in 2-3 days
as a cause of GI bleed / obstruction / pain → Ba causes attenuation of gamma photons
2. Recent in-vivo labeled RBC study in few days
→ Pertechnetate may adhere to RBC
3. CIx for ionizing radiation
Radiopharma 99mTc-pertechnetate → Localizes in normal & ectopic gastric mucosa in diverticulum
- Typical dose: 200 MBq (2.5 mSv ED)
- Max dose: 400 MBq (5 mSv ED)
Preparation NBM for 6hrs, unless emergency
May give H2-antagonist (Cimetidine or Ranitidine), to ↑ uptake of 99mTc-pertechnetate by gastric mucosa
Technique - Empty the bladder, to prevent bladder from obscuring diverticulum
- Supine position
- Gamma camera over stomach, abdomen & pelvis
- Administer IV 99mTc-pertechnetate
- Dynamic imaging
Acquire: Posterior & lateral images
Aftercare None
Complication None
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BILIARY SYSTEM
A. Cholescintigraphy / Hepatobiliary Iminodiacetic Acid (HIDA) Scan
Indications Indications: Contraindications:
1. Assessment of neonatal jaundice, TRO biliary atresia 1. No absolute
2. Assessment of GB, CBD, sphincter of Oddi 2. CIx for ionizing radiation
3. Assessment of biliary drainage / obstruction
4. Suspected biliary leakage (trauma or surgery)
5. Acute cholecystitis
Radiopharma 1. 99mTc-trimethylbromo-iminodiacetic acid (TBIDA) – Hepatic IDA (HIDA)
- Typical dose: 80 MBq (1 mSv ED)
- Max dose: 150 MBq (2 mSv ED)
- After IV injection → Binds wt protein → Enters canaliculi → Excreted without being conjugated
2. 99mTc-pertechnetate → To demonstrate stomach outline
- Dose: 10 MBq (0.13 mSv ED)
Preparation T. Phenobarbitone 5mg/kg/day in 2 divided dose, 3-5 days before procedure (to promote hepatocyte uptake)
NBM for 6hrs
Sedation for infants, investigated for biliary atresia
Technique - Supine position
- Gamma camera over anterior abdomen, wt liver at the top of FOV
- Administer IV HIDA
Dynamic imaging: 1-min images, for 45mins
- When GB is visualized (30-45mins after injection), liquid fatty meal (300mls full cream milk) given to stimulate GB contraction
Dynamic imaging: 1-min images, for 45mins
- If GB & duodenum are not seen, acquire static images at intervals, up to 4-6hrs
- If GB & duodenum still not seen after 4-6hrs (possible biliary atresia) , acquire another image at 24hr
Cholecystokinin (CCK) provocation: To assess GB, CBD, sphincter of Oddi
When GB is well visualized (30-45mins after injection),
Give IV CCK infusion over 2-3mins, to stimulate GB contraction & sphincter of Oddi relaxation
Dynamic imaging: 1-min images, for another 30mins
Morphine provocation: To assess for acute cholecystitis
If GB is not seen by 60mins,
Give IV morphine infusion 0.04 mg/kg over 1min, to stimulate sphincter of Oddi contraction
Dynamic imaging: 1-min images, for another 30mins
If GB is not seen after 90mins → Confirm diagnosis
Analysis Normal HIDA scan: Biliary atresia – No demonstration of biliary excretion
Aftercare None
Complication Adverse effects of CCK & morphine
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GENITO-URINARY TRACT
A. Dynamic Renal Scintigraphy / DTPA scan
Indications Indications: Assess renal functional status Contraindications:
1. Renal impairment 1. No absolute
2. Obstructive uropathy 2. CIx for ionizing radiation
3. Renal artery stenosis
4. Reflux nephropathy
5. Renal trauma
6. Assessment of renal transplant
Radiopharma 1. 99mTc-diethylene triaminepentacetic acid (DTPA)
- Typical dose: 150 MBq (1 mSv ED)
- Max dose: 300 MBq (2 mSv ED)
DTPA does not bind well to plasma protein → Cleared by glomerular filtration(Can be used to calculate GFR)
Cheap but poorer quality
2. 99mTc-mercaptoacetyltriglycine (MAG-3)
- Typical dose: 100 MBq (0.7 mSv ED)
- Max dose: 200 MBq (1 mSv ED)
MAG-3 binds to plasma protein → Cleared by tubular absorption (80%) & glomerular filtration (20%)
Better quality but expensive
Preparation Well hydrated
Empty bladder
Technique - Supine position
- Gamma camera over posterior abdomen
- Administer IV DTPA
Dynamic imaging: 10-15 frames, for 30-40 mins
- If poor excretion is seen in 1 or 2 kidneys, after 10-20 mins, IV Lasix 40mg given
Dynamic imaging: 10-15 frames, for another 15 mins
- At the end of examination, if there is significant retention in kidneys, ask patient to void & walk ard for 1min
Take a further spot image
- All images taken in posterior
Additional techniques: To assess GB, CBD, sphincter of Oddi
a) Pre & post-captopril study
- To diagnose RAS
- Images taken before & 1hr after Captopril (25-50 mg)
b) Indirect micturating cystography
- To diagnose VUR
- After renography, dynamic images taken from 2mins before to 3mins after micturition
Analysis 1. Kidney time activity (renogram) curves
2. Relative function figures
3. Perfusion index
4. Parenchymal & whole kidney transit time
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Aftercare None
Complication None
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MUSCULOSKELETAL SYSTEM
A. Bone Scan
Indications Indications: Contraindications:
1. Staging of cancer 1. No absolute
2. Staging of primary bone tumours 2. CIx for ionizing radiation
3. Bone & joint infection
4. Bone & joint infarction (AVN)
5. Complications of metabolic bone disease
6. Trauma (equivocal on x-ray)
7. Arthropathies (RA)
8. Assessment of multifocal disorders (Paget’s disease)
9. Prosthesis assessment (loosening, infection)
Radiopharma 99mTc-methylene diphosphonate (MDP)
- Typical dose: 500 MBq
Max dose: 600 MBq (3 mSv ED)
SPECT: 800 MBq (5 mSv ED)
- Site of uptake: Areas of active bone formation (osteoblastic) / repair, areas of amorphous CaPO4
- Excreted by kidneys
Preparation Well hydrated
Technique - Supine position
- Patient in position on gamma camera, FOV preferably whole skeleton
- Administer IV 99mTc-methylene diphosphonate
- Encourage patient to drink plenty &PU frequently (to ↓ radiation dose)
PU immediately before imaging (to prevent bladder obscuring sacrum & pelvis)
- Studies:
a) Standard study Static imaging 2-4 hrs after injection
6hrs for patient wt renal impairment
b) 3-phase study (i) Arterial phase: Dynamic imaging for 1min after injection (at area of interest)
(for infection, infarction, → Demonstrate perfusion of an area
1o bone tumour) (ii) Blood-pool phase: Dynamic imaging at 5mins after injection (at same area)
→ Demonstrate blood pool d/t blood stagnation
(iii) Delayed phase: Static imaging 2-4 hrs after injection (as for standard study)
→ Demonstrate the amount of bone turnover
- Images taken:
a) Whole skeleton
b) Anterior view (may take oblique view to separate sternum & spine)
c) Posterior view (to assess posterior ribs, scapula, shoulder)
d) Magnified views (to assess small bones & joints)
May compliment wt SPECT, for better localization (3-D)
Analysis Detection of hot spot:
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B. Bone Mineral Density Scan: Dual-Energy X-ray Absorptiometry (DXA / DEXA scan)
Indications Indications: Contraindications:
1. Osteoporosis 1. No absolute
- To diagnose osteoporosis 2. CIx for ionizing radiation
- To assess the risk of fracture 3. Recent contrast study (2 weeks)
- To monitor osteoporosis treatment - Barium studies
2. Conditions related to osteopororsis - CT scan / MRI
a) Lost height - Nuclear medicine
b) Unexpected fracture
c) On medications (steroids)
d) Post-transplant
e) Hormonal problem
- Post-menopausal
- On treatment of prostate ca
- HyperPTH
Preparation - No history of recent contrast study (2 weeks)
- Should not take Ca2+ within 24hrs before the test
Technique - Usual tested bone: Spine (lumbar), hip, forearm
- Uses X-ray to measure the density of Ca2+ & other minerals in a segment of bone
2 beams of low-dose X-ray wt distinct energy peaks, sent through the bones being examined
(1 beam is mainly absorbed by soft tissue, the other mainly by bones)
X-rays that pass through will be read by detector placed behind
- Bone mineral density = Total amount – Soft tissue amount
- Types of devices:
a) Peripheral devices: (Clinic setting)
- Measure density in forearm, wrist, finger, heel
- A small portable machine wt space for forearm / foot to be imaged
b) Central devices: (Hospital setting)
- Measure density in spine & hip
- Consist of a platform for patient to lie on & an overhead mechanical arm over the body
Analysis 1. Area mineral density
- Unit: g cm-1
2. T-score:
- Subject’s bone density compared to healthy young adult of same sex
- Unit: Number of standard deviation, from the average
> -1 Normal
-1 to -2.5 Osteopenia
< -2.5 Osteopororsis
3. Z-score:
- Subject’s bone density compared to someone of same age, sex, ethnic group & weight
- Unit: Number of standard deviation, from the average
<2 Abnormal bone loss d/t sth other than aging
Aftercare None
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