Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Acts by (1) Acute • Hypersensitivity • GI: N&V, Before:
binding to the bacterial to azithromycin, diarrhea, loose
P site of the  Check for doctor’s
exacerbation any macrolide stools, abdominal
Zmax 50S order
of COPD due antibiotic, or pain, gastritis,
ribosomal
erythromycin. flatulence  Assess for history of
subunit and to Hemophilus allergy to the drug to
Generic may inhibit influenzae, • In clients who • CNS: Dizziness, reduce the risk of
Name: RNA- Maraxella are not eligible for headache, hypersensitivity
dependent catarrhalis, or outpatient PO drowsiness, reaction
protein S. therapy. fatigue, vertigo
Azithromycin synthesis by
 Monitor vital signs to
pneumoniae. establish baseline data
stimulating • Use with
the (2) Those who p+imozide.
Classification dissociation
s: can take PO During:
of peptidyl t-
RNA from
therapy for
mild  Administer with food
ribosomes.
Antibiotic, or milk to improve
Rapidly community-
Macrolide tolerability
absorbed and acquired
distributed  Follow with water
pneumonia.
widely after ensuring that the
Dosage/ throughout patient swallowed the
Frequency/ tablet whole.
the body.
Route:
Food  Teach patient to avoid
increases the sun exposure and use
absorption of protection when
500 mg/ OD/
Oral
azithromycin. outside
After:
Sources:
 Document
2007 Edition administration of drug
PDR Nurse’s  Monitor patient
Drug response to the drug
Handbook by
Spratto, G. &
Woods, A
 Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility
name of Action
Brand Name: Effective (1) Serious • Blood • CNS: Headache, Before:
against infections due dyscrasias, active dizziness, vertigo,
anaerobic  Check for doctor’s
to susceptible organic disease of confusion,
V Flagyl I.V. bacteria and order
anaerobic the CNS incoordination,
protozoa.
irritability,  Monitor vital signs to
Specifically bacteria • Consumption of
weakness, seizures establish baseline data
Generic inhibits resistant to alcohol during
Name: growth of clindamycin, use. • GI: N&V, dry
trichomonae chloramphenic mouth, metallic During:
and amoebae ol, and taste, diarrhea,
Metronidazol by binding to  Do not give by IV
e penicilin abdominal bolus, administer each
DNA,
resulting in
discomfort, dose over 1 hour
(2) constipation
loss of helical  Tell the patient not to
Classification Pneumonia,
structure, not to consume
s: strand
emphysema,
alcohol until at least
breakage, and lung 48 hours after therapy
inhibition of abscess due to completed
Trichomonac nucleic acid bacteroides  Observe for S&S of
ide,
synthesis, and fragilis
Amebicide CNS toxicity.
cell death.
Well
absorbed After:
Dosage/
Frequency/
from GI tract
Route: and widely  Document
distributed in administration of drug
body tissues.  Monitor patient
500 g / q8h/ response to the drug
IV

Sources:

2007 Edition
PDR Nurse’s
Drug
Handbook by
Spratto, G. &
Woods, A.

Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Works by used in the • Hypersensitivity • Nausea, Before:
increasing treatment of to doxofylline or to vomiting,
intracellular asthma and  Check for doctor’s
level of cyclic-
any of the epigastric pain,
Ansimar other order
3’,5’- ingredient cephalalgia,
adenosine obstructive lung irritability,  Assess for history of
disorders. It is • Acute MI allergy to the drug to
Generic
monophosphat insomnia,
e (cAMP); used to manage tachycardia, reduce the risk of
Name: • hypotension
adrenergics by the symptoms extrasystole, hypersensitivity
increasing like wheezing, reaction
production and tachypnea,
Doxyfylline phosphodiester
chest tightness hyperglycemia,  Monitor vital signs to
ase inhibitors and shortness of albuminuria. establish baseline data
by decreasing breath  Assess lung sounds
Classification breakdown. associated with before administration
s: Increased lung disorders.
levels of cAMP
produce During:
Antiasthmati bronchodilatio
c & COPD n.  Provide glass of water
Preparations Corticosteroid upon administration
s act by
decreasing  Monitor pulmonary
airway function tests
Dosage/
inflammation. periodically during
Frequency/
Route: therapy to determine
effectiveness of
medication.
400 mg/ BID  Observe for wheezing.
/ Oral If conditions occur,
withhold medication
and notify physician
Sources:
After:
https://
www.scribd.co
m/doc/
 Document
21220854/ administration of drug
 Monitor patient
response to the drug
 Advise patient of the
adverse effects of the
drug

Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Works by Febuxostat is • hypersensitivity • Gout flares, Before:
 decreasing indicated for reaction to xanthine
serum uric the chronic allopurinol deposition,
Atenurix  Check for doctor’s
acid in a management Dizziness, Rash,
Generic dose- • Use cautiously in order
of Nausea, Abnormal
Name: dependent patients with  Assess for history of
hyperuricemia LFTs, Arthralgia
manner. In major CV disease, allergy to the drug to
healthy in patients thyroid disorders, reduce the risk of
Febuxostat subjects, with gout who increased risk for hypersensitivity
febuxostat have an urate formation reaction
decreased the inadequate
Classification  Monitor vital signs to
mean serum
s: response to a establish baseline data
uric acid and
serum maximally
xanthine titrated dose of
Xanthine
During:
concentration allopurinol,
Oxidase s, as well as who are  Administer
Inhibitor
the total intolerant to medication with or
urinary uric without food.
allopurinol, or
acid
Dosage/ for whom  Provide glass of water
excretion.
Frequency/ treatment with upon administration
Route:  Advise patient that
allopurinol is
not advisable. concomitant
prophylaxis with an
40 mg / OD /
Oral
NSAID or colchicine
for gout flares may be
used
Sources:

2007 Edition After:

PDR Nurse’s
Drug  Document
Handbook by administration of drug
Spratto, G. &
 Monitor patient
Woods, A.
response to the drug