COC Model Questions for Level IV Pharmacy, 2023

1. One is not a plant medicinal effect: -

A. Atropa belladonna B. Tinea capitis C. Opium poppy D. Digitalis purpurea
2. The methods of extraction suitable for heat sensitive plant constituents is
A. Soxhlet B. Refluxing C. Percolation D. Decoction
3. The Technical name for the time period from placing order to receiving the products is
A. Ordering time B. Review period C. waiting time D. Lead time
4. Inflammatory conditions associated with asthma and other lung disease are
A. Mucolytic agents B. Surfactants C. Corticosteroids D. Anti- infective
5. The virus causing COVI D- 19 is very dangerous mainly due to its high
A. Morbidity rate B. Mortality rate C. Transmission rate D. Cure rate
6. On which of the following area do patients need drug information from
Pharmacy profession?
A. Methods of preparation B. Duration of therapy
C. Inventory of medicine D. Manufacturer name
7. Bone marrow depression is major risk associated with: -
A. Chlorpromazine B. Chloramphenicol C. Amoxicillin D. Ceftriaxone
8. PPF 400000 I U I M BI D f or 7 days. How many vials should be dispensed f or this patient
A. 3 vials B. 4 vials C. 2 vials D. 1 vials
9. Folic acid supplement is highly advised to be taken by women in child bearing agent;
A. Vomiting and morning sickness
B. Shortage of follicle stimulating hormone
C. Shortage of acidity in the amniotic fluid
D. Congenital abnormality on the fetus
10. The " seven rights" of medication does not include
A. Time B. Route C. Pharmacy D. Drug
11. Which drug quantification method estimates the need for specific drugs based on the expected
incidence of common disease?
A. Adjusted consumption method
B. Service level projection budget requirements
C. Consumption method
D. Morbidity method
12. Ototoxicity and nephrotoxicity usually occurs due to: -
A. Azithromycin B. Amoxicillin C. Streptomycin D. Chloramphenicol
13. Once the past few decade’s non communicable diseases are dramatically increasing in Ethiopia.
This can be due to: -
A. Poor sanitation
B. Weak technologic advancement
C. Expansion of sedentary lifestyle
D. The country's agriculture - based economy
14. Motion sickness can be treated with
A. Gentamicin B. Chloramphenicol C. Dimenhydrinate D. Pethidine
15. The first step in team leadership is
A. Coordinating and balancing
B. Establishing a clear vision
C. Sharing responsibility
D. Providing the information
16. According to the Ethiopian regulations one of the following drug is not stocked in a drug
Storage?
A. Clonazepam B. Cloxacillin C. Amoxicillin D. Clotrimazole
17. One of the following Drug classes must not be dispensed without a prescription
A. Antacids B. Antihistamines C. Antibacterial D. Antihelminthics
18. Pyridoxine given to a patient of tuberculosis prevents
A. Ethambutol induced visual defects
B. Isoniazid induced peripheral neuropathy
C. Rifampicin induced hepatotoxicity
D. Streptomycin induced nephrotoxicity
19. Eye contact, facial expression, gestures and touch are: -
A. Non- verbal communication B. Verbal communication
C. Written communication D. Barrier to communication
20. Management of pharmaceutical service should be based on principles and processes of
management and this method is
A. Planning B. Organizing C. Monitoring D. Shining
21. An anti-hypertensive drug having better safety during pregnancy are
A. Lisinopril B. Enalapril C. Candesartan D. Methyldopa
22. Development of vaccine for diseases caused by viruses is commonly difficult mainly due to: -
A. Very rapid mutation on viral genetic materials
B. Shortage of excipients for manufacturing of vaccines
C. Cold storage condition of vaccines
D. Very small size of viruses
23. In planning and organizing work environment scanning is an example of
A. SWOT Analysis B. VEN Analysis
C. ABC Analysis D. Pharmaceutical Analysis
24. Simvastatin is a medication that is used to lower and manage high level of ___
A. Uric acid B. Blood sugar
C. Sodium D. Cholesterol
25. An order is written f or 500 ML of NS to infuse 40 drops/ minutes
A. 2500 minutes B. 25 minutes
C. 125 minutes D. 250 minutes
26. Which drug increases the absorption of vitamin D?
A. Calcium B. Vitamin C C. Vitamin A D. Potassium
27. Which one of the following product don’t need to sterilizing;
A. Eye drops B. rectal implants C. IV- infusion D. Syrup
28. Which one of the Ethiopian traditional medicine bone settlers
A. Debtera B. Wogesha C. Weqaby D. Kalicha
29. Which one of the f following Drug is used for type I diabetes mellitus?
A. Metformin B. Glibenclamide C. Insulin D. Dailol
30. Drugs which have potentially of life saving are categorized as: -
A. Vital B. Essential. C. Less Essential D. Non-Essential
31. The local anesthetics frequently administered in combination with adrenaline used to;
A. To delay systemic absorption of the anesthetic
B. To decrease metabolic degradation of the anesthetic
C. To enhance systemic absorption of the anesthetic
D. To decrease the hypersensitivity reactions of the anesthetic
32. Who is the most appropriate person by profession that can code drugs or adopt the national code?
A. Pharmacy professional B. Pharmacy accountant
C. Nurse/health officer/physician D. CEO
33. One of the prescription information is used to adjusting the dose of drugs?
A. Sex B. Age C. Address D. Diagnosis
34. For PCP adjunctive treatment prednisolone 40 mg BI D f or 5 days,
then 30 mg BI D f or 5 days, then 20 mg BI D f or 5 days, then 10 mg BI D f or 5 days, then 10 mg QD
f or 5 days if the available dose of prednisolone is 10 mg calculate total prednisolone dispensed f or 25
days ?
A.110 B. 100 C. 105 D. 210
35. On which of the following are patient needs drug information from pharmacy professions?
A. Amount to be taken B. Frequency of administration
C. Brand name D. All of the above
36. The positive effect of cosmetics is___?
A. Skin rash B. Cleansing skin C. Hypersensitivity
37. The most activities in business is ___?
A. Monitoring daily activities
B. Monitoring weakly activities
C. Monitoring monthly activities
D. Monitoring yearly activities
38. Which one is mismatched about strategies to improve drug use?
A. Educational methods ➡ use of formulary manuals and STGs
B. Managerial methods ➡ drug use evaluations

C. Regulatory methods ➡ drug and antibiotic restrictions

D. Educational methods ➡ controlling of pharmaceuticals
39. The process of making free from disease causing the compound room is
A. Asepsis B. Pyrogenic C. Antigenic
40. A 10- years old boy who was taking anti- epileptic drug developed an overgrowth of gum tissue
(gingival hyperplasia) this patient was most likely receiving which of the following agents ?
A. Ethosuximide B. Clonazepam
C. Phenobarbitone D. Phenytoin
41. Information about remaining balance of stock on hand can be obtained from___?
A. Store issue voucher B. Bin Card
C. Store requisition from D. Goods receiving notes
42. A skill very important in team work f or team building : -
A. Driving skill B. Selling skill
C. Presentation skill D. Communication skill
43. Provision of technical KAI ZEN and enterpreneunal skill support needs more in: -
A. Micro, small and medium enterprises
B. Research centers
C. Universities
D. Corporate companies
43. Clavulanic acid is combined with amoxicillin because: -
A. It kills bacteria that are not killed by amoxicillin
B. It reduces renal clearance of amoxicillin
C. It counteracts the adverse effect of amoxicillin
D. I t inhibits B - lactamase that destroy amoxicillin
44. Training should be organized with a purpose to: -
A. Use allocated budget before year end
B. Record best performing individuals
C. Entertain team members away from workplace
D. Develop low performing individuals
45. Which one of the following is not basic function of skin cosmetics?
A. Beauty the skin B. Delivery of systemic drugs
C. Masking scars D. Cleaning the skin
46. Pare to principle (20/80) is similar with drug classification of.....
A. ABC classification B. Pharmacological classification
C. Dosage form classification D. Therapeutic classification
47. It is not main factors contributing for the success of micro and small business;
A. Focus on service B. Minimize overhead cost
C. Planning D. Maximize overhead cost
48. Among the following drugs, gynecomastia is side effect related with____?
A. Cimetidine B. Magnesium hydroxide
C. Omeprazole D. Esomeprazole
49. Tinnitus is a common side effect of _____?
A. Chloroquine B. Mefloquine
C. Quinine D. Primaquine
50. If a Hospital as an annual total consumption of Carbamazepine Syrup of 1000 bottles. What is the
average monthly consumption in the product was stocked out f or 61 days in the review period?
A. 7 Bottles B. 100 Bottles C. 60 Bottles D. 83 Bottles

51. Anemia is associated with______?

A. Lamivudine B. Zidovudine C. Nevirapine D. Stavudine
52. How can you establish quality specification for work out and work performance?
A. Assisting in assembling and dis assembling process
B. Quality consultation and testing
C. Monitoring
D. Assisting in planning and implementing of quality assurance procedure
53. A 48 year’s old man has diagnosed with TB &has been treated f or 2 months Will Isoniazid and
Rifampicin with good response, but that patient develops Numbness and parenthesis in the
extremities what will you most likely do next?
A. Add Pyridoxine B. Add vitamin E
C. Stop Isoniazid D. Replace I NH with Streptomycin
54. Advice to “keep medication for ten minutes on skin and rinse “given during dispensing of
Antifungal?
A. Ointments B. Shampoos C. Creams D. Lotions
55. The mechanism of Norfloxacin is
A. Cell wall synthesis inhibition
B. Folate synthesis inhibition
C. DNA Gyrase inhibition
D. Cell membrane synthesis inhibition
56. An 18 year’s old girl come to your health institutions for advice after a rape attack by a known HI
V positive man, what do you advice and recommended to this case?
A. To take Co-trimoxazole f or opportunistic infections
B. To start ART treatment immediately after consulting a physician
C. To take post exposure prophylaxis after consulting a physician
D. To wait f or her CD4 count to reach below 200 to start ARV treatment
57. Among the documents used for drug supply management, the one used as a consumption record;
A. Goods receiving note B. Store requisition form
C. Daily dispensing register (DDR) D. Store issue voucher
58. Among the communication process steps; one is used by the speaker to ensure the listener has
properly understood the message is: -
A. Encoding B. Feedback.
C. Channel of communication D. Decoding
59. Which type of quality control focuses on making sure the processes are functioning correctly?
A. Control charts B. Process control C. Acceptance sampling D. Process protocol
60. CNS disturbance and bad night mare may occur with
A. Zidovudine B. Efavirenz C. Lamivudine D. Diazepam
61. Which of the following is not a psychotropic substance?
A. Chlorpromazine B. Clonazepam
C. Morphine D. Carbamazepine
62. Drugs used to treat erectile dysfunction should be used with precaution because they have____?
A. Psychological addiction.
B. Sexual impotence risks
C. Cardiovascular risks
D. Infertility risks
63. A class example of loop diuretic drugs: -
A. Furosemide B. Nicotinamide C. Hydrochlorothiazide D. Spironolactone
64. ABC Analysis of drugs can be made based on total annual cost of each drug in our Hospital drug
list to identify y and compute the few items which are major budget consumers. This can be
simply be computed by using micro soft office suit software:
A. MS Word B. MS Access C. MS Excel D. MS Power point
65. Which one of the following statement is TRUE about Coartem (Artemether + Lumefantrine)?
A. It is contraindicated during the 1st and 2nd trimester of pregnancy
B. Administering with fatty meal or milk decreases its oral absorption
C. It is contraindicated for children less than 5kg of body weight
D. It is first line drug to treat complicated falciparum malaria
66. A patient on antibacterial drug treatment, complains about having tinnitus and impaired hearing,
which one of the following drug is the patient taking?
A. Amoxicillin B. Cotrimoxazole C. Gentamycin D. Doxycycline
67. Which of the following drug is not needed in emergency room?
A) Vasoconstrictor drugs B) Activated Charcoal C) Vitamin
68. If two drugs with the effect taken together and produce an effect that is equal in magnitude to the
sum of the effects of the drugs given individually, the interaction is known as
A) Antagonism B) Additive effect C) Potentiation D) Synergism
69. Which of the following drugs is obtained from a plant?
A) atropine B) insulin C) iron sulfate D) heparin
70. An adverse effect produced by drugs on fetuses is called _________.
A) Carcinogenic B) teratogenic C) pathogenic D) toxic
71. If a Health Center has a stock on hand of 30 bottles of a product, and the calculated consumption
is 55 bottles, if the product was stocked out for 5 days in the review period, how much bottles
should the HC order?
A) 90 bottles B) 80 bottles C) 500 bottles D) 25 bottles
72. The well-known anti-malarial drug Coartem is:-
A. Not contraindicated for children less than 5Kg of body weight
B.A drug derived from cinchona bark
C. Not a drug that is at risk of resistance by the microorganism
D.A drug with component derived from plant origin
73) One of the following drugs is safe during pregnancy?

A. Methyldopa B. Enalapril C. Furosemide D. Losartan

73. Which one of the following shows the right drug management cycle?

A. Drug selection---drug procurement---drug use---drug distribution

B. Drug storage---drug procurement---drug distribution---drug use
C. Drug selection--- drug procurement--- drug distribution--- drug use
D. Drug use--- drug selection--- drug procurement--- drug distribution

74. X-ray film will be damaged if exposed to

A. Humidity B. Light C. Moisture D. All of the above

75. An order is written for 500 mL of NS to infuse at 40 drops/min. How long would it take to infuse
the NS if the set delivers 20 drops/mL?
A. 2500 minutes B. 250 minutes C.25 minutes D.125 minutes
76. To decrease GI absorption of toxins we should immediately:
A. Give activated charcoal C) Give milk
 B. Make GI Surgery D) put the patient on hemodialysis
77. Which one of the following alternative medical practices treats diseases by using remedies that
produce effects different from those produced by the disease under treatment?
A. Allopathy
B. Homeopathy
C. Acupuncture
D. Ayurveda