SILLIMAN UNIVERSITY

INSTITUTE OF CLINICAL LABORATORY SCIENCES

MT 52 - SECOND SEMESTER CLINICAL INTERNSHIP

ALLIED CARE EXPERTS (ACE) DUMAGUETE DOCTORS, INC.

IMMUNOLOGY AND SEROLOGY SECTION

DECEMBER 19-22, 2023

A NARRATIVE REPORT

SUBMITTED TO: MS. ERICA MEI SYSING

SUBMITTED BY: JIA ROSE C. TABAL

 For my section this week, I am now assigned to Immunology and Serology. For the past

hospital I’ve been, there was no Immunology and Serology section on its own. They were

combined to Clinical Chemistry and Blood Bank. The study of the immune system in humans,

including its diseases, is known as immunology. In serology it is the study of blood serum (clear

fluid that separates when blood clots).

In the laboratory this section literally focuses on recognizing antibodies. These are the

proteins that a particular kind of white blood cell produces in reaction to an alien material

(antigen) within the body. Looking into immunological system issues, these include autoimmune

illnesses, which occur when the body's immune system assaults its own tissues, and

immunodeficiency disorders, which occur when the immune system is underactive. Assessing

the suitability of organs, tissues, and fluids for transplantation

First thing to do in this section is that reading the previous shift's endorsing the

department and is followed by a section area temperature check. Maintaining track of upcoming

tests also requires logging into the laboratory information system. With approval from the on-

duty medical technologist, interns can perform the required test or tests on an existing patient

specimen. When patients request particular serological testing, the laboratory has the following

equipment accessible.

As I explore this section, I encountered 3 different machines, Architect i1000sr, Wondfo

Finecare Meter Plus, and Arkray ADAMS A1C Lite HA-8380V. First is the Architect i1000sr,

the chemiluminescence microparticle immunoassay (CMIA) principle of this apparatus is that

the sample concentration is directly proportionate to the light released from the internal chemical

reaction. The Architect machine is capable of conducting numerous tests; however, the test's
accessibility is contingent upon the availability of the reagents. Hepatitis panels, thyroid panels,

troponin I tests, and cancer indicators such CA 19-9, CA 153, CA 125, CEA, and AFP are a few

of the tests available. Secondly is the Wondfo Finecare Meter Plus, an immunochromatographic

test using fluorescence is the basis of this apparatus. It uses a kit to do experiments in the lab.

This equipment is used by medical technologists at ACEDDI for various tests such as D-dimer,

hemoglobin A1C (HbA1c), procalcitonin (PCT), C-reactive protein (CRP), and N-terminal pro-

b-type natriuretic peptide (NT-proBNP).

Lastly, the Arkray ADAMS A1c machine analyzes patient blood samples that are put in

an EDTA tube. This device solely tests for hemoglobin A1C (HbA1c), which is what I was

exposed to during my rotation in the IS division. Whereas both Finecare and Arkray are capable

of performing HbA1c testing, Finecare exclusively handles specimens in an EDTA microtainer

tube, whereas Arkray employs a standard EDTA tube. High performance liquid chromatography

is the foundation upon which the machine operates (HPLC).

Overall, I gained a lot of knowledge and experience in this section. The different Medical

Technologists taught me underlined how crucial accuracy and focus on detail are to laboratory

work. As a result, accuracy of results directly affects patient diagnosis and therapy; for this

reason, meticulousness is vital.

I really had a great time in this section because I was able to explore this section with

some people who helped me a lot understood Immunology and Serology. With the machines that

I mentioned made my life easier in this section and they were really advance to have me just wait

and input the results.