 Experimental Animals:-The most commonly used animals are Mice, Rat, Rabbit,

Guineapig.
• Mice:- Mice (Albino white swiss strain) are the smallest laboratory animal
used. They are easy to breed and maintain. They are small in size, 20-30 g & easy
to handle. They are sensitive to most of the drug used in experimental
pharmacology.
eg- testing Analgesic, CNS acting drug, Chemotherapeutic agent and Toxicity
Studies.
• Albino Rat:- White rat wistar strain are the most commonest laboratory animal
used in experimental pharmacology. They are easy to breed and maintain. Rat being
small in size (200g) resemble human of several organ function. They are sensitive
to most of the drug used in experimental pharmacology.
• Guineapig (400-600g):- The commonly used experimental animals. They are very
docile, easy to breed and maintain. Therefore they are used in experimental asthma.
Guineapig tissue such as ileum is a most common tissue preparation to study
antispasmodic. Some times they are also used to study local anaesthetic.
• Rabbit(2-3kg):-Domestic rabbits are generally used for pyrogen testing. Some
of the tissue or organ from rabbit used are heart,duodenum, and ileum.