PSG COLLEGE OF PHARMACY, COIMBATORE

PHARMACOLOGY-III

MULTIPLE CHOICE QUESTION

1. Which of the following medications is a bronchodilator that acts on beta-2

adrenergic receptors?
a) Ipratropium bromide
b) Salmeterol
c) Montelukast
d) Theophylline
2. Inhaled corticosteroids are used to treat:
a) Bacterial pneumonia
b) Allergic rhinitis
c) Asthma
d) Tuberculosis
3. The mechanism of action of short-acting beta-2 agonists involves:
a) Blocking histamine receptors
b) Increasing calcium influx in smooth muscle cells
c) Stimulating beta-2 adrenergic receptors, leading to bronchodilation
d) Inhibiting phosphodiesterase, raising cAMP levels
4. Which of the following medications is a leukotriene receptor antagonist?
a) Albuterol
b) Beclomethasone
c) Montelukast
d) Prednisolone
5. A common side effect of albuterol use is:
a) Drowsiness
 b) Constipation
c) Tremor
d) Fungal infection
6. What is the main mechanism of action of theophylline?
a) Inhibition of cholinesterase
b) Antagonism of muscarinic receptors
c) Inhibition of phosphodiesterase, raising cAMP levels
d) Direct relaxation of bronchial smooth muscle
7. Which of the following medications is NOT typically used for the first-line
treatment of asthma?
a) Short-acting beta-2 agonist
b) Long-acting beta-2 agonist
c) Inhaled corticosteroid
d) Leukotriene receptor antagonist
8. Which medication is used to treat cystic fibrosis by thinning mucus
secretions?
a) Dornase alfa
b) Salmeterol
c) Fluticasone
d) Zafirlukast
9. What is a potential complication of long-term use of oral corticosteroids for
respiratory conditions?
a) Bronchitis
b) Osteoporosis
c) Cataracts
d) All of the above
10. Nebulized medications are administered through:
a) Injection
 b) Inhalation
c) Oral ingestion
d) Topical application
11.Which of the following medications can cause paradoxical
bronchoconstriction (worsening of asthma symptoms)?
a) Ipratropium bromide
b) Albuterol
c) Nedocromil
d) Cromolyn sodium (Same as Nedocromil)
12.Anticholinergic medications, such as ipratropium bromide, work by:
a) Stimulating beta-2 adrenergic receptors
b) Blocking muscarinic receptors, causing bronchodilation
c) Inhibiting the release of inflammatory mediators
d) Increasing mucociliary clearance
13.Which medication is used to treat pulmonary fibrosis?
a) There is no specific medication to cure pulmonary fibrosis, but some
medications can help manage symptoms.
b) Prednisolone
c) Albuterol
d) Montelukast
14.What is the primary use of nasal corticosteroids?
a) Treatment of acute bronchitis
b) Prevention of allergic rhinitis (hay fever) symptoms
c) Relief of chronic obstructive pulmonary disease (COPD) symptoms
d) Treatment of pneumonia
15.What is a potential side effect of using decongestants for an extended
period?
a) Improved sense of smell
b) Rebound congestion (worsening congestion after the medication wears off)
c) Increased energy levels
d) Reduced risk of allergies
16.Cough suppressants are used to treat:
a) Productive cough (with mucus)
b) Unproductive cough (dry cough)
c) Both productive and unproductive coughs
d) Neither productive nor unproductive coughs
17.How do expectorants work to treat coughs?
a) By numbing the cough reflex
b) By thinning mucus secretions, making them easier to cough up
c) By constricting bronchial airways
d) By reducing inflammation in the respiratory tract
18.Which of the following medications is an example of a cough
suppressant?
a) Guaifenesin (Expectorant)
b) Dextromethorphan
c) Pseudoephedrine (Decongestant)
d) Theophylline
19.Antibiotics are used to treat:
a) Viral infections
b) Bacterial infections
c) Fungal infections
d) Allergic reactions
20.What is an important consideration when using antibiotics for
respiratory infections?
a) Only use them if symptoms are severe.
b) Complete the entire course of medication, even if symptoms improve.
c) They can be used to prevent future infections.
d) All of the above
21.Antiviral medications are used to treat:
a) Bacterial pneumonia
b) The common cold (caused by viruses)
c) Chronic bronchitis
d) Asthma
22.What is a potential side effect of using some antiviral medications?
a) Development of antibiotic-resistant bacteria
b) Nausea and vomiting
c) Increased risk of fungal infections
d) All of the above
23.Oxygen therapy is used to treat:
a) Mild asthma attacks
b) Respiratory failure
c) Allergic rhinitis
d) Acute bronchitis
24.Which type of inhaler device is commonly used for delivering
short-acting bronchodilators?
a) Metered-dose inhaler (MDI)
b) Dry powder inhaler (DPI)
c) Nebulizer
d) All of the above
25.Proper inhaler technique is important to ensure:
a) Medication reaches the intended target in the lungs
b) Minimizes side effects
c) Both a and b
d) Neither a nor b
26.What is a spacer device used for with MDI inhalers?
a) To deliver a higher dose of medication
b) To improve coordination with inhalation
c) To convert the medication to a nebulized form
d) To treat a wider range of respiratory conditions
27.What are some potential complications of chronic obstructive
pulmonary disease (COPD)?
a) Respiratory failure
b) Increased risk of heart disease
c) Pneumonia
d) All of the above
28.Smoking cessation is the most important intervention for managing:
a) Asthma
b) Acute bronchitis
c) Chronic obstructive pulmonary disease (COPD)
d) Pulmonary fibrosis
29.What is the primary goal of pulmonary rehabilitation for patients with
chronic respiratory conditions?
a) To cure the underlying disease
b) To improve exercise tolerance and quality of life
c) To prevent future respiratory infections
d) To reduce the need for medications
30.How do decongestants work to relieve nasal congestion?
a) By constricting blood vessels in the nasal passages
b) By thinning mucus secretions
c) By reducing inflammation