Sr no Plant name, family, Experiment details Results References

part used
1. Fragaria Aim of the Study: To Najda, A., Dyduch-
Sieminska, M., Dyduch, J., &
vesca ,Rosaceae compare the The results suggest Gantner, M. (2014).
Parts Used: phytochemical and variations in the Comparative analysis of
secondary metabolites
 Fragariae antioxidant activity of wild phytochemical
contents in Fragaria vesca L.
folium (leaves) strawberry fruits (Fragaria composition and fruits. Annals of Agricultural
 Fragariae radix vesca L.), analyzing antioxidant activity and Environmental
(roots) secondary metabolites in of wild strawberry Medicine, 21(2)
fruits based on their
 Fragariae relation to the origin of
origin, with natural
fructus the raw material (natural
habitat fruits
(aromatic habitats vs. cultivation). showing higher
fruits), Parameters Analyzed: levels of
 Flavonoids flavonoids,
 Sum of phenolic phenolic acids,
acids tannins,
 Tannins anthocyanins, and
 Anthocyanins better DPPH
 DPPH (2,2- radical reduction
ability compared to
diphenyl-1-
cultivated ones.
picrylhydrazyl)
radical reduction
Comparison Factors:
 Comparison of
wild strawberry
fruits from
natural habitats
vs. cultivation.

3. Fragaria vesca,  HPLC: Identified Fragaria vesca Couto, J., Figueirinha, A.,
Batista, M. T., Paranhos, A.,
rosaceae,leaves flavonoids, extracts showed Nunes, C., Gonçalves, L. M.,
phenolic acids, antioxidant ... & Pina, M. E. (2020).
Fragaria vesca L. extract: a
ellagitannins, and activity.
promising cosmetic
proanthocyanidin Hydrogel ingredient with antioxidant
s. demonstrated properties. Antioxidants, 9(2)
, 154.
 ROS Scavenging cutaneous
Activity: compatibility,
Assessed stability, and
antioxidant antioxidant
potential. efficacy.
 Cytotoxicity: In vivo studies and
Ensured safety human patch
for skin use. testing supported
 In Vivo Studies: safety and efficacy
Explored effects for topical use.
on living
organisms.

4. Fragaria vesca, The study aimed to 50% glycerin Ivanov, I. G. (2018).

Determination of biologically
Rosaceae, Leaves and compare phytochemical extracts active substances with
 flowers compounds and
antioxidant activities in
various extracts obtained
from Fragaria vesca leaves
and flowers. The
extraction methods
included infusion,
decoction, glycerine
extracts, and tinctures.
The analysis focused on
secondary metabolites
content, encompassing
total polyphenols, total
tannins, and total
proanthocyanidins.
Additionally, antioxidant
activities were assessed
using DPPH and FRAP
methods.
5. Fragaria vesca, The study aimed to
Rosaceae, Leaves investigate the vascular
effects of Fragaria vesca
extracts, particularly from
the leaves. The
experiment involved the
use of internal thoracic
arteries (ITAs) obtained
from patients with
coronary artery disease
who were undergoing
cardiac surgery.
demonstrated the antioxidant potential in
different extracts of Fragaria
highest levels of vesca L. leaves and
total polyphenols, flowers. Journal of
total tannins, total Pharmacognosy and
Phytochemistry, 7(5), 2733-
proanthocyanidins 2737
and antioxidant
activities .The
study suggested
that these glycerin
extracts from
leaves and flowers
are suitable
additives for
emulsion
preparation in
natural cosmetic
products,
enhancing
biological activity.
Furthermore, 50%
ethanol was
identified as the
optimal solvent for
tincture
preparation,
yielding the
highest extraction
of biologically
active substances
the study found (Malheiros, Simões et
that Fragaria vesca al. 2022)
extracts,
particularly from
leaves, did not
elicit vasorelaxant
effects on human
arteries harvested
from patients with
underlying
coronary artery
disease. The study
emphasized the
need for additional
research to fully
grasp the potential
clinical
applicability of
Fragaria vesca
extracts in
cardiovascular
disorders
6. Fragaria vesca, This study aimed to
Rosaceae, Leaves explore whether extracts
from the leaves of wild
strawberries (Fragaria)
and raspberries (Rubus)
have any effects on the
cells in our circulatory
system, specifically
focusing on their
potential toxicity,
antioxidant activity, and
how they interact with the
membranes of blood cells.
7. Fragaria vesca, The study assessed
Rosaceae, Leaves tyrosinase inhibition and
formulated a gel with
hydroxyethylcellulose,
ethanol, and water.
Various tests, including
physicochemical
characterization, stability
tests, total tannins
measurement, in vitro cell
culture assays, in vivo
safety, and efficacy tests,
were conducted. The
antioxidant efficacy
against UVA irradiation
was evaluated by
monitoring skin color
changes
the study suggests (Cyboran-Mikołajczyk,
that extracts from Męczarska et al. 2022)
the leaves of wild
strawberries and
raspberries, rich in
ellagitannins, do
not harm blood
cells. Instead, they
seem to bind to
the surface of cells,
changing their
physical
properties.
Importantly, these
extracts
demonstrated
strong antioxidant
abilities, protecting
cells from damage
caused by free
radicals. The
findings open the
possibility of these
extracts being
used in preventing
diseases related to
the cardiovascular
system, although
more specialized
tests are needed
for confirmation.
the wild (Couto, Figueirinha et
strawberry leaf al. 2020)
extract displayed
tyrosinase
inhibitory activity,
suggesting
potential benefits
for skin health.
The gel
formulation
proved stable and
safe in both in
vitro and in vivo
tests. While the
extract showed
cytotoxicity at a
certain
concentration, the
gel formulation

Fragaria vesca, The study focused on
Rosaceae, fruit assessing the antioxidant
activity of Fragaria vesca,
examining various
secondary metabolites
present in the fruits. The
antioxidant activity was
evaluated using the DPPH
radical neutralization
ability method. Extracts
were prepared from both
fresh and air-dried fruits
of Fragaria vesca. The
experiment aimed to
understand how different
cultivars, as well as the
state of the fruit (raw or
dried), influenced
antioxidant activity.
exhibited no
toxicity. Both the
extract and the
gel showed
antioxidant
activity against
UV radiation or
hydrogen
peroxide. In vivo
tests confirmed
the antioxidant
efficacy through
skin color
analysis,
indicating
protection against
oxidative damage
induced by UV
radiation. Safety
tests, including
patch tests and
human repeated
insult patch tests
(HRIPT),
supported the
good
compatibility of
the hydrogel
formulation with
the skin.
, Fragaria vesca, (Dyduch-Siemińska,
specifically the Najda et al. 2015)
Regina cultivar,
demonstrated
notable
antioxidant
activity,
highlighting the
importance of
cultivar selection
and fruit state in
harnessing the
plant's health
benefits.
need access from library :

https://doi.org/10.1016/j.indcrop.2014.10.021

https://doi.org/10.1016/j.jep.2014.09.043

A comparative study of the antibacterial activity of the ethanolic extracts of Vitex negundo
L., Fragaria vesca L., Terminalia arjuna and Citrus maxima.

https://web.s.ebscohost.com/abstract?
site=ehost&scope=site&jrnl=22312218&asa=Y&AN=90539941&h=dqrgmHIIJeiBf7uCJzXLNsApid9dkb
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%3d&crl=c&resultLocal=ErrCrlNoResults&resultNs=Ehost&crlhashurl=login.aspx%3fdirect%3dtrue
%26profile%3dehost%26scope%3dsite%26authtype%3dcrawler%26jrnl%3d22312218%26asa%3dY
%26AN%3d90539941

https://doi.org/10.1016/j.jpba.2017.12.005

Couto, J., et al. (2020). "Fragaria vesca L. extract: a promising cosmetic ingredient with antioxidant
properties." Antioxidants 9(2): 154.

Cyboran-Mikołajczyk, S., et al. (2022). "Protection of Erythrocytes and Microvascular Endothelial Cells
against Oxidative Damage by Fragaria vesca L. and Rubus idaeus L. Leaves Extracts—The Mechanism of
Action." Molecules 27(18): 5865.

Dyduch-Siemińska, M., et al. (2015). "The content of secondary metabolites and antioxidant activity of
wild strawberry fruit (Fragaria vesca L.)." Journal of analytical methods in chemistry 2015.

Malheiros, J., et al. (2022). "Vascular effects of Fragaria vesca L. in human arteries." Natural Product
Research: 1-6.