BIOINFORMATICS

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NR
Code No: B0308
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
M.Tech II Semester Supplementary Examinations March/April 2010
BIOINFORMATICS
(BIOTECHNOLOGY)
Time: 3hours Max.Marks:60
Answer any five questions
All questions carry equal marks
---

1. What is the need of Bioinformatics in the field of B.T? Explain various


applications of Bioinformatics. [12]

2. What is the need of Biological data bases and explain about the management and
architecture of DNA sequence databases. [12]

3. Write short note on the following


a)
b)
Sequence assembly
Restriction site checking

L D [6+6]

4.

5.
O R
Discuss about various methods employed in DNA sequencing?

Describe about the methods employed for RNA Structure Prediction.


[12]

[12]

6. Explain the following


a)
b)
Dot Matrix Analysis.

U W
Dynamic Programming method of Sequence Alignment. [6+6]

7.
T
Explain the role of multiple sequence alignment in Phylogenetic analysis?

N
[12]

J
8. Describe about the various physical properties of proteins to be considered in
protein sequence Analysis. [12]

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