الامتحان البرومترك الجديد

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antiarrythmic class 1b is:

lidocain*

delpets the catecholamins's store :


reserpsin *

not dispensed without a prescription :


aspirin
baclofen
maalox
ibuprofen
doxycyclin

‫انا مش عارف االجابه‬

used as a nasal decongestant :


ephedrine and phenyephirin*

cyclocystine used as :
mucolytic*

how nitroglycerin work as anti angiana:


‫مش فاكر االختيارات‬

when the exp. date is november 2006 that means u can dispense the product untill date :
1 november 2006
15 november 2006
31 novermber 2006
1 novermber 2007
15 novmber 2007
‫مش عارف االجابه‬

‫مساله عن ال‬molarity

‫ ومساله عن ال‬ppm

bioequivalence determine by factors of :


*1- pharmaceutical kinteics
2- pharmaceutical dynaimics
3- weight
...........................

when 2 producats have identical but not same active ingredients are :
1
a-pharmaceutical alternatives
b- pharmaceutical equivalents
c- bioequivalent
c- biological
e- a and b
f - b and c

1- The major action of sodium chromoglycate is


a-mast cell stabilization
b-bronchodilator 2
c-prostaglandins modifier
d-leukotrienes modifier
e-non of the above

2-The action of histamine is:


a-capillary constriction
b-elevation of blood pressure
c-stimulation of gastric secretion
d-skeletal muscle paralysis
e-slowing the heart rate

3-One of the following antibiotics is resistant to penicillinase:


a-penicillin V
b-penicillin G
c-floxapen (flucloxacillin)
d-ampicillin
e-amoxicillin

4- Inderal is:
a-similar in action to ergotamine
b-similar in action to tubocurarine
c-used as an antihistamine
d-pure β-adrenergic receptor blocker
e- α and β-adrenergic receptor blocker
2
5- Rifampicin is indicated for treatment of:
a-impaired fat absorption
b-pulmonary emboli
c-tuberculosis
d-neoplastic disorders
e-psoriasis

6- Which of the following is selective β1-blocker?


a-labetalol α & β-blocker
b-terazosine selective α1-blocker
c-cloridine selective α2-agonist
d-captopril ACE inhibitor
e-verapamil calcium channel blocker

None of them is a selective β1-blocker

7- The Latin abbreviation for "After Meals" is:


a- a.c. before meals
b- a.a. for each
c- p.c.
d- i.c.
e- c.c. cubic centimeter= 1ml

8- The Latin abbreviation for "Four Times Daily" is:


a- a.c.
b- a.a.
c- p.c
d- q.i.d quater in die
e- c.c.

9- The Latin abbreviation for "Every Night" is:


a- a.c.
b- o.n. omni nocte

3
c- p.c
d- i.c
e- c.c

10- Erythroped A:
a-is effective against G +ve Cocci and G –ve bacteria
b-is a macrolide antibiotic
c-can increase g.i.t. motility
d-could be used in pregnant women if need
e-all of the above

11- For the treatment of anaphylactic shock use:


a-salbutamol
b-diphenhydramine
c-acetazolamide
d-epinephrine
e-aminophylline

? 12- Allopurinol is used as:


x a-analgesic agent
x b-uricosuric agent (as probenecid),
x c-anti-inflammatory agent
x d-antipyretic agent
? e-agent which increases renal tubular reabsorption
13- Which of the following is NOT betamethasone side effect?
a-cataract
b-hypoglycemia
c-skeletal muscle weakness
d-sodium retention
e-lowered resistance to infections

14- A disease which is due to viral infection:


a-poliomyelitis
b-rabies
c-chicken pox
d-herpes
e-all of the above

15- The mechanism of action of atropine is


a-muscarinic antagonist
b-muscarinic agonist
c-nicotinic antagonist
d-nicotinic agonist

4
e-none of the above

16- Myocardial muscle tissue property to generate electrical is:

a-inotropy (=contractility = the force of muscle contraction)


b-chronotropy (= affecting a time or rate, as in heart rate)
c-automaticity (= a property of specialized excitable tissue that allows self-activation
through spontaneous development of an action potential, as in the pacemaker cells of the
heart)
d-contractility
e-none of the above

17- The heart's dominant pacemaker is:


a- AV node
b- SA node
c-purkinje fiber
d-internodal pathways
e-non of the above

18- Adenosine is used for:


a-ventricular arrhythmias
b-atrial bradycardia
c-supraventricular tachycardia
d-supraventricular bradycardia
e-none of the above

19- Adenosine P produces which of the following:


a-facial flushing
b-dyspnea
c-marked tachycardia
d- a and b
e- a , b and c

20- Which of the following is responsible for buffering


a-magnesium
b-chloride
c-bicarbonate
d-potassium
e-troponin

21- Respiratory acidosis is due to:


a- O2 removal
b- O2 retention
c- CO2 removal

5
d- CO2 retention
e-none of the above

22- Which of the following is NOT colloid solution?


a-albumin 5%
b-ringer's solution
c-dextran
d-beta starch
e-albumin 20%

23- The term shock signifies:

a-hyperperfusion
b-hypoperfusion
c-tachycardia
d-bradycardia
e-non of the above

24- In treatment of shock, which of the following should be considered?


a-airway control
b-IV of crystalloid solution
c-dopamine to support blood pressure
d-monitor heart rhythm
e-all of the above
25which of the following is released by bacterial infection? (...by bacterial cell wall during
their growth
a-endotoxin
b-exotoxin
c-antibiotics
d-cytotoxin
e-none of the above

26- The amount of water in adult male is about:


a-25%
b-60%
c-80%
d-10%
e-17%

27- Which of the following are causes of oedema?


a-increase hydrostatic pressure
b-decrease oncotic pressure
c-increase capillary permeability
d- a and b
e- a, b and c

28- Patients prescribed non reversible monoamine oxidase inhibitor should be advised not
6
to consume food containing tyramine because this combination causes:
a-postural hypotension
b-hallucinations
c-anaphylactic shock
d-muscle weakness and tremor
e-acute adrenergic crisis including sever hypertension

29- Concerning COX 2 inhibitors, which is NOT true?


a-they have lower risk of gastric adverse reactions
b-good evidence about their effectiveness
c-cardiac toxicity is a recent concern of this class
d-they usually administrated twice daily
e-combination with non selective agents give more effective action
30- In the treatment of osteoporosis which of the following is NOT true?
a-alendronate should be taken 60 min. before breakfast
b-Ca and vit. D are essential
c-hormone replacement therapy should be considered
d-outcome should be assessed with periodic bone density
e-raloxifeo is a selective oestrogen receptor modulator

31- Which of the following is the first choice in acute gout?


a-allopurinol
b-indomethacin
c-colchicine
d-probencid
e-sulfinylpyrazone

32- Which of the following is NOT a risk factor for osteoparalysis?

a- minimal exercise
b- low calcium intake
c- male gender
d- family history
e- minimal exposure to sunlight

33- Early symptoms of aspirin poisoning are:


a- lethargy & fatigue
b- skin rash & headache
c- throbbing headache & dizziness
d- fluid retention hypotension
e- ringing in the ears & blurred vision

34- Which of the following is NOT true about infiximab


a- IL-1 blocker
b- used for treatment of severe rheumatoid arthritis
7
c- may increase risk of infections
d- administered as IV infusion
e- post administration reactions include fever & chills

35- A disease modifying drugs in rheumatoid arthritis:

a-gold preparations
b-hydroxychloroquine
c-methotrexate
d- a and b
e- a, b and c

36- A patient who is admitted through the E.R. with an initial diagnosis:

a-slow ventricular response using verapamil


b-start lidocaine infusion
c- considered anticoagulation with warfarine
d- a and b
e- b and c
??

37- Which of the following is true about surgical prophylaxis?


a- it is given to treat surgery associated infections
b-it is given to reduce the possibility of surgical site infection
c-should always be given regardless type of surgery
d-should be continued for 7 days after surgery
e-all are true

38- Goals of diabetes mellitus management include:


a-reduce onset of complications
b-control symptoms of diabetes
c-near normal glycemic control and HBA1c
d- a and b
e- a, b and c

39- When dosing insulin which of the following is true?


a-initial dose 0.6 u / kg / day split 2/3 a.m and 1/3 p.m
b-regular NPH ratio is 1 : 1 or 1 : 2
c-dose may need to be increased during acute illness
d- b and c
e- a, b and c

40- What first line agent may be considered for an obese type 2?
a-glyburinid
b-insulin
c-metformin
8
d-nateglinid
e-repaglinid

41- When diagnosis of diabetes to be considered:


a-WBC count with differential
b-oral glucose tolerance test
c- HBA1c
d- a and b
e- b and c

42- A 4 mg dose of lorazepam administered to an adult will act as:


a-analgesic
b-hypnotic
c-diuretic
d-antihistaminic
e-antiulcerant

43- The usual daily dose of phenytoin in the range of:

a- 300-600 g
b- 1-5 mg
c- 15-60 mg
d- 300-600 mg
e- 1-2 mg

44- The drug of choice to control pain during acute myocardial infarction is:
a-naloxone
b-bethidine
c-morphine
d-celecoxib
e-naproxen

45- What is a major contraindication to the use of an OTC sympathomimetic drug

a-gastric ulcer
b-uncontrolled hypotension
c-severe asthma
d-rheumatoid arthritis
e-hypertension

46-Category C in FDA for drug used in pregnancy:

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a- controlled studies fail to demonstrate a risk to the fetus in the trimester and there is no
evidence of risk in later trimester
b- fetal risk NOT demonstrated in animal studies but there are no controlled studies in
pregnant women or animal reproduction studies have shown an adverse effect that was
NOT confirmed in controlled studies in women during trimester
c-either animal study have revealed adverse effect on the fetus and there are no controlled
human studies or studies in animal and women are not available
d- There is positive evidence of human fetal risk but the benefits of use in pregnant woman
may be acceptable despite the risk

47- What advice would you give to a patient prescribed rifampicin?


a-take this medication with food or milk
b-avoid multivitamin preparations during treatment
c-avoid taking paracetamol during treatment
d-possible discolouration of skin is of no importance
e-this medication may cause discolouration of urine

48- Correct method of parentral administration of potassium is:


a-fast I.V. injection
b-slow I.V. injection
c-I.M. injection
d-IP(intraperitoneal) injection

49- Which of the following drugs exhibits dose dependant pharmaceutical therapeutic
doses?
a-Na valproate
b-phenytoin
c-lithium
d-quinidine
e-carbamazepine

50- Which route of administration would provide the most rapid onset of action response to
morphine?
a-oral
b-S.C.
c-I.V.
d-I.M.
e-rectal

The long term administration of thiazide diuretics requires:


a- K+
b- Na+
10
c- Ca++
d- CO3
e- acetate

52- Propranolol is often prescribed with


hydralazine to

a-reduce the reflex tachycardia


b-prevent the accumulation of hydralazine
c-prevent systemic lupus ( SLE ) due to hydralazine
d-prevent oedema
e-increase absorption of hydralazine

53- Fifty micrograms equals:


a-50000 ( nanogrames )h g
b- 0.05 ( micrograms )m g
c- 0.0005 g
d- a and b
e- a and c

54- The ability of a liquid to dissolveis:


a-hydrophilicity
b-miscibility
c-immiscibility
d-solubility equilibrium
e-solvation energy

55- These are non aqueous pharmaceutical solutions:


a-otic soln. , mouth washes and nasal soln.
b-essences, collodions and elixirs
c-gargles, douches and irrigation soln.
11
d-syrups , mucillages and collodions
e-enemas , liniments and spirits

56- A solution is made by dissolving 17.52 g of NaCl in exactly 2000 ml. What is
the molarity of this solution?
a- 3.33
b- 0.15
c- 1.60 x 10-4
d- 0.30
e-3.00 x 10-4

Molarity = no. of moles/ volume (Liter)


No. of moles = weight (gm) / molecular weight = 17.52 / (23+35.5) = 0.3 moles
M = 0.3/ 2 = 0.15

57- Which of the following is NOT correct?


a-glitazones are ineffective as mono therapy
b-GIT disturbance are common side effects of a-glycosidase inhibitors
c-start with small dose of oral agent and triturate up to 1-2 weeks
d-life style modification should not be enforced if an oral agent to be started
e-lispro is a rapid acting insulin to be dosed immediately before meals

58- In CHFmanagement the following is not correct:

a-ACEIs such as lisinopril improve left ventricular function and reduces mortality

b- -blockers such as Carvedilol may have beneficial effect in selected patients

c-spironolactone should be avoided because of the great risk of hypokalemia

12
d- non drug therapy includes appropriate fluid and dietary sodium-restriction

e-symptomatic improvement is one of the major assessment criteria for proper


therapy

59- When considering drug therapy for hypertension, which is true?


a-combination of drugs always preferred
b-hydralazine is first line therapy in young hypertension
c-furosemide should be administrated before meal to improve absorption
d-beta-blokers should be avoided in asthmatic patient
e- ACEIs are recommended in pregnant women

60- Which of the following is NOT a primary literature


a-journal of pharmacy practice
b-applied therapeutic & clinical use of drugs
c-new England Journal of medicine
d-Loncet e- JAMA
Primary literature: journal articles
Secondary literature: textbooks
Tertiary literature: reference books: dictionaries, encyclopedias

61- Which of the following is NOT used in theophylline toxicity management:


a-symptomatic control of seizures with benzodiazepine
b-activated charcoal to enhance elimination
c- -blocker for tachycardia
d-control vomiting with metoclopramide
e-methylphenidate to reduce excessive sedation

62- Regarding the use of ACEIs:


a-associated hypokalemia could be avoided by giving K-supplement
b-effective in reducing proteinurea in diabetic patient
c-most common side effect is chronic dry cough
d-a good first line treatment for hypertensive diabetic
e-dose should be started low and triturated gradually upward in need

63- References to check compatibility of drugs in parentral administration:


a- MERCK Index
b-handbook on injectable drugs
c-micro comedix
d- a and b
e- b and c

13
64- Regarding treatment of digoxin toxicity:
a-verify time of last time
b-check Mg and K levels and correct if needed
c-monitor ECG
d-no antidote for digoxin
e-supportive care

65- When a CNS depressant is prescribed, which of the following is NOT taken at the same
time?
a-analgesic
b-verapamil
c-aspirin
d-diphenhydramine
e-orange juice

68-The following is NOT characteristic of solution:


a-thermodynamically stable
b-composed of two or more components that exist in one phase
c-homogenous
d-the solvent and solute can be separated by filtration
e-solute doesn't precipitate as time passes

‫المهم رابط االمتحان هو‬

http://pharma.programerz.com

1_inderal is
(propranolol)whicl is adrenergic beta blocker

2_propranolol is
beta blocker

3_salbutamol is

14
selctive b1 agonist

4_which is false about nor epinephrin


a_ effictive orally
b_can used in cardiogenic shock
c_can used subcutanous
d_raise blood pressure
the answer is (a

5_which is the folowing block the alpha receptor in vains and arteries and amke v.d.
a_terazosin
b_minoxidil
c_propranolol
answer is a

6_syncop may occure with the 1st dose of the folowing


a_digoxin
b_salbutamol
c_prazosin
d_reserpin
e_ clonidin
answer is c

7_one of the fllowing used in asthmatic patient


answer is albuterol

8_the pharmacolpgical action of clofibrate is


decreas action of lipoprotienlipase enzyme
b_increase clolesterol synthis
c_decreas lipoprotien synthes
d_decrease cholesterol absorption

answer is c

9_one of the following has cathertic effect


a_ca carbonat
b_magnesium oxide
c_alimenium hydroxide
d_sodium bicarbonate

answer is b

10_loratidin is
a_ca channel blocker
b_ laxitave
c_antihistaminic
d_anti hypertension

answer is c
15
11_which of the following not anti bacterial
..........

12_which one is more effective agaienst traveller diarrhea

a_amoxiciilin
b_ciprofloxacin
c_sulphamethoxasol
d_erythromycin

i think amoxicillin is right

13_which is the following istrue about erythromycin


a_decrease the GIT motility
b_could be used in pregnant women if need
c_could not be used in pregnant women if need
d_less active against gram +ve cocci
answer is b

14_which one is active against psoudomonal


a_metronidasol
b_ampicillin
c_becampicilline
d_imipinem
anwere is d
‫مش متاكد‬

_15_A 4 mg dose of lorazepam administered to a adult will act as :


a-analgesic
b-hypnotic
c-diuretic
answer b
16_ the action of TCA is
inhibit reuptak of noradrenalin and serotini

17_Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses
?
a-Na valproate
b-phenytoin
c-lithium
answer is b

18_The long term administration of thiazide diuretics requires :


a- K+
b- Na+
c- Ca++
16
answer is a

19_antihypertensive produce tackycardia :


a)Hydralazone
b)Reserpine
c)Methyldopa
d)Atenolol
e)Clonidine
answer is a

20_ the pharmacological action of nitroglycerin is

21_the action of digoxin can reduced with


a_ antacid
b_verapamil
hypokalemia
d_hypothirodism
e_hyperthyrodism
answer is a
22_ the main cause of digitalis toxicity is
a_diabetes milli
b_ hypertension
c_hepatitis
d_renal faliure
i think d

23_digitalis arrhythmia can be treated with


a_lidocain
b_quinidin
c_procainamide
d_propranolol
answer is a

24_which one used in ventricular arrhthmia with heart block


answer is phynetoin

25_the action of antiarrhythmic drug classs 1A is


a_rapid the repo;arization of phase 0
b_delay the repolarization of phase 3
answer is b

26_which one is antiarrythmic class 1A


a_phynetoin
b_disopyramide
c_propranolol
d_verapamil
e_propafenon
answer is b

17
27_which one doesnt affect platellet in the body
a _ aspirin
b_dipyridamol
c_acetyl salcylic
d_captopril
e_clopidogril

answer is d

28_action of theophyllin
a_vasocostrector
b_ bronvhodilator
c_anti arrythmia
answer is b

29_anti cancer derived from venca is_


a_cyclophosamide
b_flourouracil
c_doxurubcin
d_ cicplastin

i think d

30_ alkylating agent used as anticancer


a_methotrexate
b_ mercaptopurin
c_5_flourouracil
d_cyclophosphamide

answer is d

31_ascorpic acid is
a_vit A
b_ vit C
c_ vit E

answer is b

32_reserpin shouldnt be used in parkinsonism patient talking..........

33_one of the following not NSAID


a_ naprocyn
b_indocid
c_ticotil
d_‫مش فاكر اسمه بس هوا ده كان االختيار اعتقد‬

34_pentoxifillin used as

18
35 _ which one used to trigeminal neuralgia
answer is tegretol
‫ وممكن برده ال‬phynetoin

‫دي كانت اسئله الفارما‬

‫المسائل‬

‫ مسائل‬5 ‫كان في‬


1_ how many doses in abottle contain 90 gram and the dose is 75mg

answer
number of dose = 90/0.75=120

2_A solution is made by dissolving 17.52 g of nacl

exactly 2000 ml. What is the molarity of this solution

answer

molarity= number of moles/volume in liter

number of moles=weightin gram/molecular weight

M.W.of NaCL=MW ob Na(23.5+MW of Cl (35=58.5

then number of mole= 17.5/58.5=0 .3

molarity = 0.3/2=0.15

3_the solution contain 9ppm of NaCl the the concevtration of the compound in the solution

a_0.9
b_.09
c_.009
d_.0009
e_.00009
0.009‫انا حلتها‬
‫بس مش عارف صح وال غلط‬.

4_ how much amount of water need to add to 250 ml of solution os 1/500 of benzonium
clorid to bacome 1/2000
a_0.125 L
b_0.250 L
c_0.4 L
d_2 L
e_ 4 L
0.4 ‫انا كتبتها‬
19
‫ومعرفش صح وال غلط‬

‫المساله الخامسه مش فاكرها‬


‫وان شاء هللا افتكر الباقي واكتبه‬

‫ بالنسبه ل‬ceutics and clinical


‫هحاول افتكر واكتب االسئله‬

1_the statement (put in cold place ) mean acoording to USP


a_ in the freezer
b_in refrigerator
c_ temp between(10_20 c)f
d_ a&c
e_ b&c

‫ انا كتبتها‬c
‫ بس متهيالي انها‬e

2_all factors affect on distribution of drug except :

a_Tissue solubility

b_Protein binding

c_Molecular weight of drug

d_Type enzyme response of metabolism

answer is d

3_ONE OF FOLLOWING NOT USED TO COVER BITTER

TASTE :

a_Film coat

b_Enteric coat

c_Granding of tablet
answer is c

4_major metabolism proccess in GIT is


a_hydrolysis
,b_ acetylation
c_oxidation
d_ conjucation
answer a
20
5_the amount of water in adult male is about:
a-25%
b-60%
c-80%
d-10%
e-17%
answer is b

6_process require CYP450 :


a)OXIDATION
b)HYDROLYSIS
c)GLUCORONIDATION
d)DEAMINATION
e)SULFERATION
‫ انا كتبتها بس معرفش صح وال غلط‬oxidation

7_Adsorption , which is not true :


a) Chemical property
b) Physical property
c) Reversible
d) Irreversible
e) A + d
answer is e

8_acording to 1st order kinetics t1/2 equal


a_k
b_1/k
c_k+1
d_2k+1
e_ 639/k
answer is e

9_the responce of the drug not affected by


a_mental status
b_genetic
c_binding to plasma ptn
d_lipophilicity of the drug

‫انا كنت محتار بين االولي والتانيه بس اخترت االولي‬

10_‫في سؤال جالي مش عارف حله بس هقوله‬


‫معني السؤال (الورقه اللي صاحب الصيدليه بيكتبها للعاملين في الصيدليه ويوجد بها تعليمات الصديليه ) دي اسمها ايه‬

‫وطبعا كان مديني اختيارات غريبه‬

11_ ‫برده سؤال تاني عن كيفيه ترتيب مستحضرات العيون في الصيدليه علي الرف‬
‫يعني مثال نرتب كاالتي (المحلول ثم المراهم ثم المعلق )او (المعلق ثم المراهم ثم المحلول) وهكذا‬

21
12_ ‫نفس السؤال اللي فات بس عن طريق الفرق في الفاعليه‬

13_about steady state concentration during IV adminestration


a_directly ptoportional to volume of distribution
b_inversly proportional to volume of distribution
c_directly ptoportional to infusion rate
d_ inversly proportional to total body clearance
e_ c&d

answer is e

14_disentegration of drug to small molecule is

a_ reduction
b_ sublimation
c_ solubility
‫ مش فاكر باقي االختيارات بس انا حلتها‬a

the way for 1st pass metabolism_15

‫ كان في اختيارات بس االجابه‬from mesentric vain to portal vain

16_ which of the following decreas gastric emptying rate


a_ metoclopramid
b_ atropin
c_ hypothyroism
d_a&b
e_b&c
answer is e

1-The action of histamine is :


a-capillary constriction b-elevation of blood pressure
c-stimulation of gastric secretion *****
d-skeletal muscle paralysis e-slowing the heart rate

2- latabbreviation for " After Meals " is :


a- a.c.
b- a.a.
c- p.c. ***
d- i.c.
e- c.c.

3-- Myocardial muscle tissue property to generate electrical is :


a-inotropy b-chronotropy
c-automaticity****
22
d-contractility
e-non of the above

4- Which of the following is responcible for buffering


a-magnesium
b-chloride
c-bicarbonates*****
d-potassium
e-troponin

5-- In treatment of shock , which of the following should not be considered?


a-airway control
b-IV of crystalloid solution
c-dopamine to support blood pressure
d-monitor heart rhythm
e-give antibiotic to treat infection*****

6-- In the treatment of osteoporosis which of the following is NOT true?


a-alendronate should be taken 60 min. before breakfast****
b-Ca and vit. D are essential
c-hormone replacement therapy should be considered
d-outcome should be assessed with periodic bone density
e-raloxifeno is selective oestrogen modulator

7- A patient who is admitted through the E.R. with an initial diagnosis is arterial fibrilation:
a-slow ventricular response using verapamil
b-start lidocaine infusion
c- considered anticoagulation with warfarine****
d- a and b
e- b and c

8 -The usual daily dose of phenytoin in the range of:


a- 300-600 g
b- 1-5 mg
c- 15-60 mg
d- 300-600 mg****
e- 1-2 mg

9- When concidering drug therapy for hypertention , which is true?


a-combination of drugs always preferred
b-hydralazine is first line therapy in young hypertension
c-furosemide should be administrated before meal to improve absorption
-blokers should be avoided in asthmatic patient ****d-
e- ACEIs are recommended in pregnant women

10- B carotine is precursor of :


a)retinol ****
b) thiamine
c)riboflavin
23
d)pyridoxine
e) calcefirol

11-antihypertensive produce tackycardia :


a)Hydralazone*****
b)Reserpine
c)Methyldopa
d)Atenolol
e)Clonidine

12-process require CYP450 :


a)OXIDATION
b)HYDROLYSIS
c)GLUCORONIDATION
d)DEAMINATION
e)SULFERATION

13-drug induced lupus like syndrom is associated with antihypertinsive ???


a) minixidil
b) phenytoin ***
c) dioxide
d) nitroprusside Na
e) acebutol

14- hypothirodism will increase :


a) body weight ****
b) body temp
c) lipid profile

15- low density lipoprotien act as :


a) Major carrer of cholestrol in plasma *****
b) transport fatty acid from cell membrane to cytoplasm,
c) good lipoprotien.........

16-patient has CHF given digoxin and thiazide and needed corticosteroid , which is best
choice?
a) Cortisone
b) Hydrocortisoce
c) Prednisolone

17- expairy date of drug is 8\2010 that means , last day you can use drug is :
a) 31\8\2010…..*****
b) 1\8\2010
c) 31\7\2010

18- digitoxin side effect :


a) Hyperglycemia
b) Hypertension

24
19- elevated blood glucose is side effect of :
Digoxin…………..

20-amphetamine used to treat :


a) Defect concentration *****
b) Insomnia

21-- which is not asthma properties :


a) Bronchodilator*****
b) Bronchospasm
c) Increase mucous secretion
d) Chest pain

22-- hormone excreted from adrenal cortex :


a) Aldosterone ******
b) Growth hormone
c) FSH

23- one of following is not alpha 1 agonist :


a) Clonidine
b) Alpha methyl noradrenaline******
c) Guanfacine
d) Guanabenz
e) Guanethidine

24- about side effect of quinidine :


Chichonism*******

25-all of following are side effects of methotrixate except:


a) Bone marrow depression
b) Alopecia
c) Nausea and vomiting
d) Stimulate sex drive ****
e) Alopecia ‫وكتب معها كمان شي‬

26- ACE inhibitors are contraindicated in :


bilateral renal artery stenosis*****

27- Adsorption , which is not true :


a) Chemical property
b) Physical property
c) Reversible
d) Irreversible
e) A + d ****

28-all are antibiotic except :


Famcyclovir *****

25
29- heparin monitoring :
a) INR
b) PT
c) APTT****

30- about digitoxin , which is false :


a) Oral bioavaiability 100%
b) Protein binding 95%
c) Half life is 7 days
d) Mainly hepatic metabolism by lysosmal ……

31-all r Beta 2 agonist except :


a) Salbutamol
b) Alburanol
c) Fenoterol
d) salmeterol
e) Pindolol *****

32-Pkw for normal water in room temperature :


a) 7
b) 14****
c) 10^7
d) 10^-14
e) C + d

33- about norepinephrine , which is not true?


a) increasr B.P
b) vasoconstrictive
c) used in cardiogenic shock
d) effective orally'*****
e) S.C

34-- o.m.......
every morning******

35- one of following not used to cover bitter taste :


a) Enteric coat
b) Film coat
c) Enteric coat
d) Grinding of tablet ****
e) B + C

36- all contraindicated in pregnancy except :


a) ACEI
b) Methyldopa****

26
37- dose of drug in children is ……. Mg \ kg , what total dose for child 34.5 bound?
‫وكان كاتب اختيارات بالوحدتين‬
gm , mg
‫ف تحويل الوحدات ضروري‬

38-drug prescriped as
1 tablet contaion 1 mg bid ( 2 weeks) , what is total dose?
28 mg*****

39- tybe 2 anti arrythmic properties :


Inhibit sympathetic system by beta adrenergic
blockade ***

40-in injection of lidocaine , what drug added to increase effectiveness of lidocaine?


Epinephrine …………..

41-about sterilization by filtration , which is false?


a) Cannot used for virus *****
b) Need special equipment

42-membrane filters with 0.22 micropores , which of following not removed by that?
a) Bacteria
b) Virus***
c) Fungi
d) A+c
e) B+c

43)volatile substance given by inhalation:


a) Halothane
b) Dextromethorphane………….

44)in prescription
Substance A 15 parts
Substance B 30 parts
Substance C 150 parts
We neeed to prepare ointment 500 gm , what amount should we take from substance A ?
‫قلت‬......‫بطريقة نسبة وتناسب‬..‫انا حليتها صح‬
15+30 + 150 = 195
‫اذا بدي اعرف كم نسبة المادة االولى من كل الوصفة‬,
(15 \195) * 100 =7.69 %

So , we need 7.69 % from all 500 gm


( 7.69 * 500 ) \ 100 = 38.46 gm
38.46 gm****
‫ مسائل حليتهم صح‬5 ‫وانا كانت عالمتي بالمسائل كاملة يعني الحمدهلل‬...‫وهو أحد االختيارات الموجودة‬

45- we need to prepare 100 ml of 0.05% substance X solution…… how gm we need from
substance X ?
27
0.05 gm***

46- loop diuretics cause all the following except:


a) Hypokalamia.
b) Hyponatrimia.
c) Hypocalcemia..
d) Hypoglycemia.
e) Hypernatremia.****

47-two drugs has same active ingredient but difrent inactive ingredient , called:
a) Pharmaceutical equivelance
b) Bioequivelance
c) A + b
d) Pharmaceutical alternative

48-to compare between 2 drugs use:


a) Physical appearance
b) Weight
c) Pharmacokinetic parameters
d) Pharmacodynamic parameter
e) Taste

49) Cardiac arrest could be managed by the following except:


a) Ephedrine.
b) Lidocine.
c) Normal saline.
d) Propranolol****

50)-Binding to plasma protein:


a- Increases half life.***
b- Decreases half life

51) The antidote of heparin is:


Protamin sulphate****

52)when gived gentamycin , which is should monitoring?


Creatinine clearance****

53-tricyclic antidepressant mechanism of action :

54-diazoxide… side effect :

55-tegretol used in :
Trigeminal Neuralgia****

56-about sid effect of oral contraceptive except :


a) Depressoin
b) Hypertension

28
57-drug dependence which is true :
a) After discontinuation , patient has withdrawal symptoms
b) Patient progressively increase dose to get same action
‫بقيت االختيارات كانت مستبعدة تماما‬

58)drug used in ventricular arrhythmia :


a) Phynetoin ******
b) Quinidine
c) Digoxin
d) Procainamide
e) Verapamil

59)Enteric coated tablets:


Are dissolved in the intestine and not affected by the stomach juices*****

60) factors affecting on dissolution rate are :


a) Increase size of particles
b) Decrease size of particles
c) Increase surface area
d) Decrease surface area
e) B + C******

19) infusion of hypotonic solution in blood cause :


a) shriniking of blood cell
b) hemolysis
c) hyperglycemia
d) hypoglycemia
e) b + d
‫ طبعا االجابة‬b .......
20) ‫ نفس السؤال السابق لكن عن‬hypertonic ‫ واالجابة تكون‬......... ‫ ونفس الختيارات‬a.....
21) when 1 part of substance require 10000 parts of solvent , it called :
very soluble , soluble , sparingly soluble , slighty soluble , insoluble ......
‫ االجابة‬slighty .......
22) which solution is colloid solution ?? ringer solution
23) tests required fordiabetic patient :
a) oral glucose test
b) HBa1c
c) WBC count
d) a+ c
e) all of above
24) patient given rifampicin , what advice him :
urine discoloration will happened
25) denaturation will happened in body for which compunds????f
penicillin , protien , lipid , carbohydrate , ............
26) major metabolism proccess in GIT is
hydrolysis , acetylation , oxidation , conjucation ,
‫ االجابة‬hydrolysis
27) in ovulation day , level of which is highest : progesterone , FSH , BOTH , LUTEINIZING
HORMONE ........
28) About side effects of hydralazine

29
‫مو متذكر االحتيارات وال عارف االجابة الصحيحة‬
29) about side effects of prozasin
30) dosage form of nitroglycren when used in malignant hypertension ???
IV , IM , S.C , infusion , transdermal ........
31) drug induced lupus like syndrom is associated with antihypertinsive ???
minixidil , hydralazine , dioxide , nitroprusside Na , acebutol .........
32) hypothirodism cause : weight gain , hypoglycemia , low body temp ...........
33) about ACE I mechanism of action as antihypertension ???
act on serotonin receptor , on dopamine receptor , inhibition of converting angiotensin I to
angiotensin II ........
34) About definition of first pass effect
, it increase with : increase rate of absorption , increase biotransformation ,both ,
increase pka
35) metal used in rheumatoid arthiritis : gold
36) drug cause or consider pressor
37) low density lipoprotien act as :
carrer cholestrol in plasma , transport fatty acid , good lipoprotien

1- Traveller,s diarrhoea microorgansim causes :


E. Coli & Bacterial enterotoxin & shilegella & campylobacter & sallomonella & Giardia
‫ دي االجابات الصح كلها و انا جاء لي في اال ختيارات‬E. Coli ‫و طبعا جاوبتها صح صدفه فقط‬
2- Traveller's diarrhoea treatment by
ciprofloxacin &norfloxacin & ofloxacin & Trimethoprin with sulpha methaxol

3- benzoyl peroxide used in ttt : acne

4- prazosin : selective alpha 1 receptor blocker

5- warfarin monitored by : INR


‫كل اجابتي اكيده الني بحثت عنها بنفسي و االجابه دي بالذات هي سبب نصيحتي في االول النها متجاوبه غلط في االول و جاءت لي في‬
‫ عرفتم بقي ليه انا موش كنت‬. ‫ يعني النقطتين دول كانوا نجحوني‬%53 ‫االمتحان مرتين و االجابتين جاوبت فيهم غلط و للعلم انا جايب‬
‫ و هللا العظيم كنت عارفها االول صح بس اللي جاوب غلط ضيع معلوماتي‬.. ‫عاوز ادخل الموقع تاني‬
6- ca channel blocker : reduce myocardial o2 demond by increase ca influx

7- causes of hypo thyrodism :


iodine deficiency , low hypothulmus&pituitary hormons
‫اعتقد ان االجابه دي كافيه الني موش فاكر االختيارات عموما دور انت و اعرف الهرمون المسئول عنها اذا كان من الغده النخاميه‬
‫الجزء االمامي او الخلفي الن دي نقطه برده تانيه موش فاكر فيها صيغة السؤال تماما‬
8- pencillin : inhibit cell wall synthesis

9- phenytoin use other anti convelcent agent :


ttt irregular heart beat & ttt painful nerve coduction (neuralgia)
‫وده اللي انا وصلتله حاولوا تاني تدوروا علي استخدامات اخري الني موش فاكر االختيارات‬
10 - ASpartam in tablet added to : sweatner agent
‫انا فاكر كده من ايام الكليه و ما بحثتش عن اجابتها بس اعتقد انها االجابه الصح الن االختيارات التي جاءت معها عبيطه جدا عيب‬
‫تختارها كصيدلي يعني‬
30
11- 10 ml i.v given drug in con 0.02% how mg in it :
0.01 mg , 1mg ,10mg ,20mg ,100mg
‫احترت فيها و احتار دليلي ياريت اي حد غيري بيفهم يجاوبهالي باي وسيله‬
12 - all ca channel blocker except :
‫احفظهم كلهم الني موش فاكر االجابات‬
13- according to britich pharmacobia drug sesitive to light shoud be put in:
amber glass bottel , amber plastic bottel , light resistant bottel
‫برده السؤال ده لسه مالقيتش له حل ياريت اللي يحله يقول لي مصدر معلومته ايه بس يكون متأكد منها‬
14- specific gravity ,volum of solvent ,gm of solute : molarity =??
‫ مسأله بنت لذينه شتتني في اال متحان و خلي بالك من االجابات الن فيها الوحده مره‬m ‫ و مره‬mol ‫و مره مافيش‬

15- verapamil in ttt arrhythmia is : class 4 antiarrhythmic drugs

16- in ruhmatoid arthritis, diclofenac :


only analgesic antiinflamatory effect , more effect with allpuranol
‫ فموش عارف بصراحه‬... ‫انا اخترت االولي و واضح ان التانيه اصح‬
17- add ing buffer to opthalmic drops to : ?????
‫ابحث عن االجابه بنفسك الني موش القيها بصراحه‬
18 - factors effect in drug distribution :
‫ابحث عن االجابه بنفسك و احفظهم كويس‬
19 - antidot action is:
‫ االجابات موش فاكرها بس انا فاكر ان منها‬interfer with binding protein
20 - ‫ هو سؤال عن‬pore size of filter ‫اللي بفلتر بيها الفيروس و البكتريا و الفطريات و البروتوزوا‬

21- Desmoprossin used for ttt necturial enuress

22- salbutamol is β2-adrenergic


receptor agonist used for the relief of bronchospasm in
conditions such as asthma and chronic obstructive pulmonary disease

23- pentophyllin is peripheral vasodilators. It dilates selectively blood vessels of the limbs,
brain and retina

24- arrhythmia due to : dysfunction in generate heart pulse or coduction of it

25- adrenal cortex hormons :aldesteron

26- paracetamol maximum daily dose : 4000mg

27- caffain action : cns stim & increase heart contraction & little vasoconstractor &stim
gastric hcl secreation & mid deuretic effect

28- antidot of heparin : protamin sulphate

29- mode of action of hydralazin : alpha 1 blocker so it direct relax of ms of artries

30- side effect of hydralazin : systemic lupus erythmatosis

31- drug of choice in ttt hypertension in pregnant : methyl dopa

32 - ‫ احفظ االعراض الجانبيه لل‬methyl dopa

32 - TB not viral infection

31
33- dopamin act in dopamin receptor in cns

34- major excratory organ : kednys

36- histamin increase prostglandin level


‫لذا الحسنه الوحيده انه بيقلل حمض المعده فبيقلل الحموضه‬
37 - acute gout ttt by cholchicin while chronic gout ttt by allpuranol

38- tladanafil present in market in : cialis


39- seldinafil presnt in market in : vigra

40- nitroglyceren : ttt angina by relax smooth ms which leads to decrease pre load and
after load

41- term PH measure acidity or basisty

42- microlids all except : ciprofloxacin


‫ هو عموما المايكروليدز اولها‬erry ‫ أو اخرها‬mycin
43-hypo thyrodism cause : wt gain & constepation & increase cholesterol

43 - aminoglycoside : not less toxicity


) ‫ أعتقد ان دي االجابه الصح (اعتقاد مبني علي اساس علمي و ليس شخصي‬- ‫بيقول اختار الجمله الصحيحه من بين جمل خاطئه‬
44- ACEI act bv : blocking ACE action to convert Angiotensen 1 to Angiotensin 2
‫ احفظ كل االدويه اللي في‬C.V.S
45 - ca channel blocker :
‫ قولت في السؤال السابق احفظ كل االدويه اللي في‬CVS ‫ و منهم طبعا‬ca channel bloker

46- parkenosonism is due to degredation of paro reptor of ?????


‫اللي يعرف يجاوب السؤال ده يقوللي عليه‬
47- pheno thiazin act as electron donator

48- promethazin act as anti hestamining & anti emetic

in ovulation day , level of which is highest : LH hormone

‫ سؤال جالي كان بيسأل عن نوع خاليا ليست من خاليا الدم البيضاء‬WBCs

Neutrophil
Eosinophil
Basophil
Lymphocyte
Monocyte
Macrophage
Dendritic cells

32
Abbrev. Meaning Latin (or New Latin) origin
a.c. Before food ante cibum
a.d. Right ear auris dexter
ad lib. Freely as wanted ad libitum
a.l. Left ear aurix laevus
alt. die Every other day alternus die
alt. h. Every other hour alternus horis
a.m. Morning ante meridiem
a.n. Before the night ante noctum
aq. Water aqua
a.s. Left ear auris sinister
a.u. Each ear auris utro
aurist. Ear drops auristillae
b.d. or bd Twice a day bis die
b.i.d. or bid Twice a day bis in die
gtt. Drop gutta
h. Hour hora
h.d. At bedtime hora decubitus
h.s. At bedtime hora somni
i.d. during the day
i.d. the same idem
i.d. intradermal, between layers of the skin
mane In the morning mane
narist. Nasal drops naristillae
nocte At night nocte
o.c. Eye ointment oculentum
o.d. or od Daily omni die
o.d. Right eye oculus dexter
o.l. Left eye oculus laevus
o.m. In the morning omni mane
o.n. At night omni nocte
o.r. Right eye oculus rectus
o.s. Left eye oculus sinister
o.u. Each eye oculus utro
p.c. After food post cibum
p.m. Afternoon post meridiem
p.o. or po Orally per os
p.r. Rectally per rectum
p.r.n. As occasion requires (as needed) pro re nata
p.v. Vaginally per vaginum
q. every quaque
q.2.h. Every two hours quaque 2 hora
q.4.h. Every four hours quaque 4 hora
q.6.h. Every six hours quaque 6 hora
q.8.h. Every eight hours quaque 8 hora
q.d. or qd Every day quaque die
q.d.s. Four times a day quater die sumendus

33
q.h. Every hour, hourly quaque hora
q.i.d. or qid Four times a day quater in die
q.q.h. Every four hours quarta quaque hora
q.s. A sufficient quantity quantum sufficiat
Rx or for symbol ℞ meaning prescription recipe
s.i.d. or sid Once a day semel in die
Sig. or S. Write on the label signa
SL. Sublingual, under the tongue sub linguam
S.O.S. When required Si opus sit
Stat. Immediately, with no delay statim
t.d.s. Three times a day ter die sumendus
t.i.d. or tid Three times a day ter in die
top. Topically, applied to the skin
ut dict. or u.d. As directed ut dictum
ung. Ointment unguentum

34

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