CLP Regulation (EC) No.

1272 / 2008
on the classification, labelling and packaging
of substances and mixtures
Rev 2, September 2017

Hazard Statements (H- Statements)(1)

GHS01 GHS02 GHS03 GHS04

(1) Are still discussed in the UN, changes may still arise.

H 200 - Series: Physical Hazards

H200: Unstable explosive
H201: Explosive; mass explosion hazard
H202: Explosive; severe projection hazard
H203: Explosive; fire, blast or projection hazard
H204: Fire or projection hazard
H205: May mass explode in fire
H220: Extremely flammable gas
H221: Flammable gas
H222: Extremely flammable material
H223: Flammable aerosol
H224: Extremely flammable liquid and vapour
H225: Highly flammable liquid and vapour
H226: Flammable liquid and vapour
H227: Combustible liquid
H228: Flammable solid
H229: Pressurised container: May burst if heated
H230: May react explosively even in the absence of air
H231: May react explosively even in the absence of air at elevated
pressure and/or temperature
H240: Heating may cause an explosion
H241: Heating may cause a fire or explosion
H242: Heating may cause a fire
H250: Catches fire spontaneously if exposed to air
H251: Self-heating; may catch fire
H252: Self-heating in large quantities; may catch fire
H260: In contact with water releases flammable gases which may ignite
spontaneously
H261: In contact with water releases flammable gas
H270: May cause or intensify fire; oxidiser
H271: May cause fire or explosion; strong oxidiser
H272: May intensify fire; oxidiser
H280: Contains gas under pressure; may explode if heated
H281: Contains refrigerated gas; may cause cryogenic burns or injury
H290: May be corrosive to metals

CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and packaging of substances and mixtures page 1
 Hazard Statements (H- Statements)(1)

(1) Are still discussed in the UN, changes may still arise.

GHS05 GHS06 GHS07 GHS08

H300 – Series: Health Hazards

H300: Fatal if swallowed
H301: Toxic if swallowed
H302: Harmful if swallowed
H304: May be fatal if swallowed and enters airways
H310: Fatal in contact with skin
H311: Toxic in contact with skin
H312: Harmful in contact with skin
H314: Causes severe skin burns and eye damage
H315: Causes skin irritation
H317: May cause an allergic skin reaction
H318: Causes serious eye damage
H319: Causes serious eye irritation
H330: Fatal if inhaled
H331: Toxic if inhaled
H332: Harmful if inhaled
H300 + H310: Fatal if swallowed or in contact with skin
H300 + H330: Fatal if swallowed or if inhaled
H310 + H330: Fatal in contact with skin or if inhaled
H300 + H310 + H330: Fatal if swallowed, in contact with skin or if inhaled
H301 + H311: Toxic if swallowed or in contact with skin
H301 + H331: Toxic if swallowed or if inhaled
H311 + H331: Toxic in contact with skin or if inhaled
H301 + H311 + H331: Toxic if swallowed, in contact with skin or if inhaled
H302 + H312: Harmful if swallowed or in contact with skin
H302+ H332: Harmful if swallowed or if inhaled
H312 + H332: Harmful in contact with skin or if inhaled
H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled
H334: May cause allergy or asthma symptoms or breathing difficulties if
inhaled
H335: May cause respiratory irritation
H336: May cause drowsiness or dizziness
H340: May cause genetic defects <state route of exposure if it is conclusively
proven that no other routes of exposure cause the hazard>
H341: Suspected of causing genetic defects <state route of exposure if it is
conclusively proven that no other routes of exposure cause the hazard>
H350: May cause cancer <state route of exposure if it is conclusively
proven that no other routes of exposure cause the hazard>
H350i: May cause cancer by inhalation
H351: Suspected of causing cancer <state route of exposure if it is conclusively
proven that no other routes of exposure cause the hazard>
H360: May damage fertility or the unborn child <state specific effect if
known> < state route of exposure if it is conclusively proven that no other
routes of exposure cause the hazard>
H360F: May damage fertility
CLP Regulation (EC) No. 1272 /H360D: May
2008 on the damage the
classification, unborn
labelling child
and packaging of substances and mixtures page 2
H360FD: May damage fertiltiy. May damage the unborn child
 H350: May cause cancer <state route of exposure if it is conclusively
proven that no other routes of exposure cause the hazard>
H350i: May cause cancer by inhalation
H351: Suspected of causing cancer <state route of exposure if it is conclusively
Hazardproven
Statements (H-
that no other routes Statements)
of exposure
(1)
cause the hazard>
H360: May damage fertility or the unborn child <state specific effect if
known> < state route of exposure if it is conclusively proven
(1) Are still that innothe
discussed other
UN, changes may still arise.
routes of exposure cause the hazard>
H360F: May damage fertility
H360D: May damage the unborn child
H360FD: May damage fertiltiy. May damage the unborn child
H360Fd: May damage fertility. Suspected of damaging the unborn child
H360Df: May damage the unborn child. Suspected of damaging fertility
H361: Suspected of damaging fertility or the unborn child <state specific
effect if known> < state route of exposure if it is conclusively proven that
no other routes of exposure cause the hazard>
H361f: Suspected of damaging fertility
H361d: Suspected of damaging the unborn child
H361fd: Suspected of damaging fertility. Suspected of damaging the unborn child
H362: May cause harm to breastfed children
H370: Causes damage to organs < or state all organs affected, if known> <
state route of exposure if it is conclusively proven that no other routes of
exposure cause the hazard>
H371: May cause damage to organs < or state all organs affected, if known>
<state route of exposure if it is conclusively proven that no other routes of
exposure cause the hazard>
H372: Causes damage to organs < or state all organs affected, if known>
through prolonged or repeated exposure < state route of exposure if
it is conclusively proven that no other routes of exposure cause the hazard>
H373: May cause damage to organs < or state all organs affected, if known>
through prolonged or repeated exposure < state route of exposure if
it is conclusively proven that no other routes of exposure cause the
hazard>

GHS09
H400 – Series: Environmental Hazards
H400: Very toxic to aquatic life
H410: Very toxic to aquatic life with long lasting effects
H411: Toxic to aquatic life with long lasting effects.
H412: Harmful to aquatic life with long lasting effects
H413: May cause long lasting harmful effects to aquatic life
H420: Harms public health and the environment by destroying ozone in the
upper atmosphere

Supplemental Hazard Information (EUH-Statements)

EUH 001 Explosive when dry.
EUH 014 Reacts violently with water.
EUH 018 In use may form flammable/explosive vapour-air mixture.
EUH 019 May form explosive peroxides.
EUH 044 Risk of explosion if heated under confinement.
EUH 029 Contact with water liberates toxic gas.
EUH 031 Contact with acids liberates toxic gas.
EUH 032 Contact with acids liberates very toxic gas.
EUH 066 Repeated exposure may cause skin dryness or cracking.
CLP Regulation (EC) No. 1272 / 2008EUH
on the classification,
070 Toxic bylabelling and packaging of substances and mixtures
eye contact. page 3
EUH 071 Corrosive to the respiratory tract.
 Supplemental Hazard Information (EUH-Statements)
EUH 001 Explosive when dry.
EUH 014 Reacts violently with water.
Hazard
EUH 018
Statements (H- Statements)(1)
In use may form flammable/explosive vapour-air mixture.
EUH 019 May form explosive peroxides.
EUH 044 Risk of explosion if heated under confinement.
(1) Are still discussed in the UN, changes may still arise.
EUH 029 Contact with water liberates toxic gas.
EUH 031 Contact with acids liberates toxic gas.
EUH 032 Contact with acids liberates very toxic gas.
EUH 066 Repeated exposure may cause skin dryness or cracking.
EUH 070 Toxic by eye contact.
EUH 071 Corrosive to the respiratory tract.
EUH 202 Cyanoacrylate. Danger. Bonds skin and eyes in seconds. Keep out
of the reach of children.
EUH 203 Contains chromium(VI). May produce an allergic reaction.
EUH 204 Contains isocyanates. May produce an allergic reaction.
EUH 205 Contains epoxy constituents. May produce an allergic reaction.
EUH 206 Warning! Do not use together with other products. May release
dangerous gases (chlorine).
EUH 207 Warning! Contains cadmium. Dangerous fumes are formed
during use. See information supplied by the manufacturer.
Comply with the safety instructions.
EUH 208 Contains <name of sensitising substance>. May produce an allergic
reaction.
EUH 210 Safety data sheet available on request.
EUH 401 To avoid risks to human health and the environment, comply
with the instructions for use.

Precautionary statements (P-statements)

P 100-Series: General

P101 If medical advice is needed, have product container or label at hand.

P102 Keep out of reach of children.
P103 Read label before use.

P 200-Series: Prevention

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and
understood.
P210 Keep away from heat, hot surfaces, open flames and other ignition
sources. No smoking.
P211 Do not spray on an open flame or other igntion source.
P220 Keep away from clothing and other combustible materials.
P222 Do not allow contact with air.
P223 Do not allow contact with water.
P230 Keep wetted with …
P231 Handle and store contents under inert gas/... page 4
CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and packaging of substances and mixtures
P232 Protect from moisture.
 understood
P210 Keep away from heat, hot surfaces, open flames and other ignition
sources. No smoking.
Precautionary statements (P-statements)
P211 Do not spray on an open flame or other igntion source.
P220 Keep away from clothing and other combustible materials.
P222 Do not allow contact with air.
P223 Do not allow contact with water
P230 Keep wetted with …
P231 Handle and store contents under inert gas/...
P232 Protect from moisture.
P233 Keep container tightly closed.
P234 Keep only in original packaging.
P235 Keep cool.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…/]equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P244 Keep valves and fittings free from oil and grease.
P250 Do not subject to grinding/shock/friction...
P251 Do not pierce or burn, even after use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P263 Avoid contact during pregnancy and while nursing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the
workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face
protection.
P282 Wear cold insulating gloves and either face shield or eye
protection.
P283 Wear fire resistant or flame retardant clothing.
P284 [In case of inadequate ventilation] wear respiratory protection.
P231 + P232 Handle and store under inert gas/.... Protect from moisture.

P 300-Series: Response

P301 IF SWALLOWED:
P302 IF ON SKIN:
P303 IF ON SKIN (or hair):
P304 IF INHALED:
P305 IF IN EYES:
P306 IF ON CLOTHING:
P308 IF exposed or concerned:
P310 Immediately call a POISON CENTER/doctor/...
P311 Call a POISON CENTER/doctor/...
P312 Call a POISON CENTER/doctor/... if you feel unwell.
P313 Get medical advice/attention.
CLP Regulation (EC) No. 1272 P314 Getclassification,
/ 2008 on the Medical advice/attention if you feel
labelling and packaging unwell. and mixtures
of substances page 5
P315 Get immediate medical advice/attention.
 P304 IF INHALED:
P305 IF IN EYES:
P306 IF ON CLOTHING:
Precautionary statements (P-statements)
P308 IF exposed or concerned:
P310 Immediately call a POISON CENTER/doctor/...
P311 Call a POISON CENTER/doctor/...
P312 Call a POISON CENTER/doctor/... if you feel unwell.
P313 Get medical advice/attention.
P314 Get Medical advice/attention if you feel unwell.
P315 Get immediate medical advice/attention.
P320 Specific treatment is urgent (see … on this label).
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P331 Do NOT induce vomiting.
P332 If skin irritation occurs:
P333 If skin irritation or a rash occurs:
P334 Immerse in cool water [or wrap in wet bandages].
P335 Brush off loose particles from skin.
P336 Thaw frosted parts with lukewarm water. Do not rub affected areas.
P337 If eye irritation persists:
P338 Remove contact lenses if present and easy to do. Continue rinsing.
P340 Remove person to fresh air and keep comfortable for breathing.
P342 If experiencing respiratory symptoms:
P351 Rinse cautiously with water for several minutes.
P352 Wash with plenty of water/..
P353 Rinse skin with water [or shower].
P360 Rinse immediately contaminated clothing and skin with plenty of
water before removing clothes.
P361 Take off immediately all contaminated clothing.
P362 Take off contaminated clothing.
P363 Wash contaminated clothing before reuse.
P364 And wash it before reuse.
P370 In case of fire:
P371 In case of major fire and large quantities:
P372 Explosion risk.
P373 DO NOT fight fire when fire reaches explosives.
P375 Fight fire remotely due to the risk of explosion.
P376 Stop leak if safe to do so.
P377 Leaking gas fire – do not extinguish unless leak can be stopped
safely.
P378 Use … to extinguish.
P380 Evacuate area.
P381 In case of leakage, eliminate all ignition sources.
P390 Absorb spillage to prevent material damage.
P391 Collect spillage.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/
doctor/...
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor/... if you
feel unwell.
P302 + P334 IF ON SKIN: Immerse in cool water or wrap in wet bandages.
P302 + P352 IF ON SKIN: Wash with plenty of water/...
P304 +P312 IF INHALED: Call a POISON CENTER or doctor/physician if
CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and packaging of substances and mixtures page 6
you feel unwell
 P390 Absorb spillage to prevent material damage.
P391 Collect spillage.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/
Precautionary statements (P-statements)
doctor/...
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor/... if you
feel unwell.
P302 + P334 IF ON SKIN: Immerse in cool water or wrap in wet bandages.
P302 + P352 IF ON SKIN: Wash with plenty of water/...
P304 +P312 IF INHALED: Call a POISON CENTER or doctor/physician if
you feel unwell
P304 + P340 IF INHALED: Remove person to fresh air and keep
comfortable for breathing.
P306 + P360 IF ON CLOTHING: Rinse immediately contaminated clothing
and skin with plenty of water before removing clothes.
P307 + P311 IF exposed or concerned: Call a POISON CENTER/doctor/..
P308 + P313 IF exposed or concerned: Get medical advice/attention.
P332 + P313 If skin irritation occurs: Get medical advice/attention.
P333 + P313 If skin irritation or a rash occurs: Get medical
advice/attention.
P336 + P315 Thaw frosted parts with lukewarm water. Do not rub affected
area. Get immediate medical advice/attention.
P337 + P313 If eye irritation persists: Get medical advice/attention.
P342 + P311 If experiencing respiratory symptoms: Call a POISON
CENTER/doctor/...
P361 + P364 Take off immediately all contaminated clothing and wash it
before reuse.
P362 + P364 Take off all contaminated clothing and wash it before reuse.
P370 + P376 In case of fire: Stop leak if safe to do so.
P370 + P378 In case of fire: Use … to extinguish.
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do not induce
vomiting.
P302 + P335 + P334 IF ON SKIN: Brush off loose particles from skin.
Immerse in cool water [or wrap in wet bandages].
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all
contaminated clothing. Rinse skin with water [or
shower].
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several
minutes. Remove contact lenses, if present and easy
to do so. Continue rinsing.
P370 + P380 + P375 In case of fire: Evacuate area. Fight fire remotely due
to the risk of explosion.
P371 + P380 + P375 In case of major fire and large quantities: Evacuate
area. Fight fire remotely due to the risk of explosion.
P370 + P380 + P375 In case of fire: Evacuate area. Fight fire remotely due to
the risk of explosion.
P371 + P380 + P375 In case of major fire and large quantities: Evacuate area.
Fight fire remotely due to the risk of explosion.
P370 + P372 + P380 + P373 In case of fire: Explosion risk: Evacuate area.
DO NOT fight fire when fire reaches
explosives.
P370 + P380 + P375 + [P378] In case of fire: Evacuate area. Fight fire
remotely
CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and due
packaging of to the riskand
substances of explosion.
mixtures page 7
[Use...to extinguish].
 P370 + P380 + P375 In case of fire: Evacuate area. Fight fire remotely due to
the risk of explosion.
P371 + P380 + P375 In case of major fire and large quantities: Evacuate area.
Precautionary statements (P-statements)
Fight fire remotely due to the risk of explosion.
P370 + P372 + P380 + P373 In case of fire: Explosion risk: Evacuate area.
DO NOT fight fire when fire reaches
explosives.
P370 + P380 + P375 + [P378] In case of fire: Evacuate area. Fight fire
remotely due to the risk of explosion.
[Use...to extinguish].

P 400-Series: Storage

P401 Store in accordance with….

P402 Store in a dry place.
P403 Store in a well-ventilated place.
P404 Store in a closed container.
P405 Store locked up.
P406 Store in a corrosion-resistant/… container with a resistant inner
liner.
P407 Maintain air gap between stacks or pallets.
P410 Protect from sunlight.
P411 Store at temperatures not exceeding … °C/… °F.
P412 Do not expose to temperatures exceeding 50 °C/122 °F.
P413 Store bulk masses greater than … kg/… lbs at temperatures not
exceeding …°C/…°F.
P420 Store separately
P402 + P404 Store in a dry place. Store in a closed container.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P403 + P235 Store in a well-ventilated place. Keep cool.
P410 + P403 Protect from sunlight. Store in a well-ventilated place.
P410 + P412 Protect from sunlight. Do not expose to temperatures
exceeding 50°C/122°F.

P 500-Series: Disposal

P501 Dispose of contents/container to …

P502 Refer to manufacturer or suppliers for information on
recovery or recycling

CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and packaging of substances and mixtures page 8
CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and packaging of substances and mixtures page 9
 Classification and Labelling is set of criteria and The National Poisons Information Centre at
rules used to determine if a chemical can cause harm to Beaumont Hospital is appointed as the body responsible
human health and the environment and involves the for the receipt of information relating to emergency health
identification and evaluation of the physical properties of a response in accordance with Article 45 and Annex VIII of
chemical, along with its health and environmental effects CLP.
and then communicating those hazards via a label.
There is a Chemicals Helpdesk to assist industry to meet
The CLP Regulation (EC) No 1272/2008 on there obligations under CLP.
classification, labelling and packaging (CLP) of substances
and mixtures entered into force on the 20th January 2009 Further sources of information, assistance and
and, following a phased transitional period, applies to all guidance can be found at the following:
hazardous substances and mixtures placed on the market. HSA Chemicals website http://www.hsa.ie/chemicals
CLP incorporates the United Nations Globally Chemicals Helpdesk email chemicals@hsa.ie
Harmonised System of classification and labelling of telephone 1890 289 389
chemicals (GHS) within Europe. GHS is updated on a
biennial basis and subsequently these updates are included ECHA website https://echa.europa.eu/regulations/clp
in CLP via an adaptation to technical progress. CLP is NPIC website www.poisons.ie
direct acting in all European Member States.
The Competent Authorities under the Chemicals
Act 2008 and 2010 in Ireland for the CLP Regulation are
the Health and Safety Authority, for industrial chemicals
and the Pesticides Registration and Control Division of the
Department of Agriculture, Fisheries and the Marine, for
plant protection products and biocides.

The content of this document is aligned up to the 10th adaptation to technical progress (ATP) to CLP. The
document is subject to change as a result of further ATPs to CLP, please check the HSA and ECHA websites for
updates. The HSA wish to acknowledge and thank the German Competent Authority, BAUA who provided the
format on which this poster is based.

CLP Regulation (EC) No. 1272 / 2008 on the classification, labelling and packaging of substances and mixtures page 10