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Spinalcord 181202085959
Spinalcord 181202085959
1. Cervical plexus
2. Brachial plexus
3. Lumbar plexus
4. Sacral plexus
Cervical Plexus
• The cervical plexus is
formed by ventral rami of
C1-C4 (C5)
• Most branches are
cutaneous nerves of the
neck, ear, back of head,
and shoulders
• The most important nerve
of this plexus is the
phrenic nerve
• The phrenic nerve is the
major motor and sensory
nerve of the diaphragm
Brachial Plexus
• Formed by C5-C8 and T1
(C4 and T2 may also
contribute to this
plexus)
• It gives rise to the
nerves that innervate
the upper limb
Trunks and Cords of
Brachial Plexus
• Nerves that form brachial plexus originate from:
– superior, middle, and inferior trunks
– large bundles of axons from several spinal nerves
– lateral, medial, and posterior cords
– smaller branches that originate at trunks
Brachial Plexus: Nerves
• Axillary – innervates the
deltoid and teres minor
• Musculocutaneous – sends
fibers to the biceps brachii
and brachialis
• Median – branches to most
of the flexor muscles of
forearm
• Ulnar – supplies the flexor
carpi ulnaris and part of the
flexor digitorum profundus
• Radial – innervates
essentially all extensor
muscles
Lumbar Plexus
• Arises from (T12) L1-L4 and
innervates the thigh,
abdominal wall, and psoas
muscle
• The major nerves are the
femoral and the obturator
Sacral Plexus
• Arises from L4-S4 and
serves the buttock,
lower limb, pelvic
structures, and the
perineum
• The major nerve is the
sciatic, the longest and
thickest nerve of the
body
• The sciatic is actually
composed of two
nerves: the tibial and
the common fibular
(perineal) nerves
Nerve plexuses - Summary
• Cervical – C1-C4
– Phrenic nerve
• Brachial – C5 – T1
(roots/trunks/divisions/cords)
– Axillary, MC, median, ulnar, radial
• Lumbar – L1-L4
– Femoral, obturator
• Sacral – L4-S4
– Sciatic (common peroneal/tibial), pudendal
5 Patterns of Neural Circuits in
Neuronal Pools
1. Divergence:
– spreads
stimulation to
many neurons
or neuronal
pools in CNS
2. Convergence:
– brings input
from many
sources to
single neuron
Figure 13–13a
5 Patterns of Neural Circuits in Neuronal Pools
3. Serial processing:
– moves
information in
single line
4. Parallel
processing:
– moves same
information along
several paths
simultaneously
Figure 13–13c
5. Reverberation:
– positive feedback
mechanism
– functions until inhibited
Figure 13–13e
Reflex activity
• 5 components of
a reflex arc
– Receptor
– Sensory neuron
– Integration
center (CNS)
– Motor neuron
– Effector
4 Classifications of Reflexes
1. By early development
– Innate or Acquired
2. By type of motor response
– Somatic or Visceral
3. By complexity of neural circuit
– Monosynaptic or Polysynaptic
4. By site of information processing
– Spinal or Cranial
Spinal Reflexes
• Range in increasing order of
complexity:
– monosynaptic reflexes
– polysynaptic reflexes
– intersegmental reflex arcs:
• many segments interact
• produce highly variable motor response
Monosynaptic Reflexes
• Have least delay
between sensory
input and motor
output:
– e.g., stretch reflex
(such as patellar
reflex)
• Completed in 20–
40 msec
Muscle Spindles
• The receptors in stretch
reflexes
• Bundles of small,
specialized intrafusal
muscle fibers:
– innervated by sensory
and motor neurons
• Surrounded by
extrafusal muscle
fibers:
– which maintain tone and
contract muscle
Postural Reflexes
• Postural reflexes:
– stretch reflexes
– maintain normal upright posture
• Stretched muscle responds by
contracting:
– automatically maintain balance
Polysynaptic Reflexes
• More complicated than
monosynaptic reflexes
• Interneurons control more than 1
muscle group
• Produce either EPSPs or IPSPs
The Tendon Reflex
• Prevents skeletal muscles from:
– developing too much tension
– tearing or breaking tendons
• Sensory receptors unlike muscle
spindles or proprioceptors
Withdrawal Reflexes
• Move body part away
from stimulus (pain or
pressure):
– e.g., flexor reflex:
• pulls hand away from
hot stove
• Strength and extent of
response:
– depends on intensity
and location of
stimulus
Reciprocal Inhibition
• For flexor reflex to work:
– The stretch reflex of antagonistic
(extensor) muscle must be inhibited
(reciprocal inhibition) by interneurons
in spinal cord
Crossed Extensor Reflexes
• Occur simultaneously,
coordinated with
flexor reflex
• e.g., flexor reflex
causes leg to pull up:
– crossed extensor reflex
straightens other leg
– to receive body weight
– maintained by
reverberating circuits
Integration and Control
of Spinal Reflexes
• Though reflex behaviors are automatic:
– processing centers in brain can facilitate or
inhibit reflex motor patterns based in spinal
cord
• Higher centers of brain incorporate lower,
reflexive motor patterns
• Automatic reflexes:
– can be activated by brain as needed
– use few nerve impulses to control complex
motor functions
– walking, running, jumping
Superficial reflexes
• Stroking of the skin elicits muscle contraction
– Involves functional upper motor pathways as well
as cord level reflex arcs
• Plantar reflex (L4-S2) Babinski is normal in
infants
– Usually indicative of CNS damage in adults
• Abdominal reflex (T8-T12)
– Absent with corticospinal lesion
Spinal Cord Trauma:
Transection
• Cross sectioning of the spinal cord
at any level results in total motor
and sensory loss in regions inferior
to the cut
• Paraplegia – transection between
T1 and L1
• Quadriplegia – transection in the
cervical region
Applied anatomy/physiology
Peripheral Neuropathies
• Regional loss of sensory or motor function
• Due to trauma or compression
• Example: if your foot “falls asleep”
Shingles
• Caused by varicella-zoster virus (chickenpox)
• After chickenpox, virus hides in neurons of spinal cord
• Later in life, attacks neurons in dorsal roots of nerves =
painful rash/blisters
• Distribution of rash corresponds to dermatome nerves
affected
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