SwissBioisostere_replacement_output_jobID387978530

Query replacement: [*:1]N1CCc2c([*:2])nn([*:3])c2C1=O --> [*:1]N1CC=Cc2c([*:2])nn([*:3])c2C1=O

Replacement Occurrences Δ Activity Δ logP Δ tPSA Target Target Class Assay ID PubMed
CHEMBL436791 9.89 p[Ki] --> CHEMBL377589 9.22 p[Ki] -0.66 (#1) 0.32 0.00 Coagulation factor X Enzyme - Protease CHEMBL868637 16730984
CHEMBL211410 10.40 p[Ki] --> CHEMBL209483 9.22 p[Ki] -1.18 (#2) 0.32 0.00 Coagulation factor X Enzyme - Protease CHEMBL868637 16730984
These data have been generated by SwissBioisostere version 2021, 03.04.2024.
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