Professional Documents
Culture Documents
Digital Milton 1St Ed Edition David Currell Full Chapter
Digital Milton 1St Ed Edition David Currell Full Chapter
Edition David
Currell
Visit to download the full and correct content document:
https://ebookmass.com/product/digital-milton-1st-ed-edition-david-currell/
Digital Milton
David Currell • Islam Issa
Editors
Digital Milton
Editors
David Currell Islam Issa
American University of Beirut Birmingham City University
Beirut, Lebanon Birmingham, UK
This Palgrave Macmillan imprint is published by the registered company Springer Nature
Switzerland AG
The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
For Mum and Dad
For Mama and Baba
Acknowledgments
The editors are grateful to all those who have made Digital Milton
possible.
David Currell was fortunate to study the history of textual media with
Bernard Muir and Milton with David Quint, two extraordinarily generous
teachers. Islam Issa has continued to benefit from all that he was taught by
Hugh Adlington.
The Birmingham City University Faculty of Arts, Design and Media’s
Research Investment Scheme bought time out for Islam Issa to work on
this project and funded the index, prepared by Nick de Somogyi. Special
thanks are due to Andrew Kehoe, as well as Gemma Moss, Tim Wall, and
Sarah Wood.
An Erasmus+ staff mobility exchange allowed the editors to spend valu-
able time working on this volume together in Beirut and Birmingham. We
are grateful to Peter Sjølyst-Jackson, Lucy Stubbs, Hala Dimechkie, and
Olga Safa for their support in making this possible.
We are also grateful to discussants and audiences at a Faculty of Arts
and Sciences Research Lunch, American University of Beirut (November
2016), and at the roundtable “Milton and the Digital Humanities,”
Renaissance Society of America Annual Meeting in Chicago (March
2017), organized by David Ainsworth and also featuring Olin Bjork,
Thomas Luxon, and John Rumrich.
For advice and helpful suggestions at various stages of the project, our
thanks to three of the contributors in particular, Olin Bjork, Angelica
Duran, and Peter Herman, in addition to Paul Edmondson, Mario Hawat,
vii
viii ACKNOWLEDGMENTS
2
The John Milton Reading Room and the Future of Digital
Pedagogy 27
Cordelia Zukerman
ix
x Contents
Index 261
Notes on Contributors
xi
xii NOTES ON CONTRIBUTORS
xv
xvi List of Figures
Digital Milton presents new scholarship on John Milton that engages with
digital methods and digital media. That this scholarship fills a book is a
sign that Milton studies is participating in the digital turn. That this schol-
arship fills a book is a sign that relationships between media and platforms
are not (and are never) simple relationships of transition or substitution,
and a sign that humanists accord unique value to both print and digital
media while grappling with the urgent and compelling challenges to which
their simultaneity gives rise. Our hopes are that Milton should have
renewed life in digital media, that scholarship should have a vital role in
this metamorphosis, and that the results should enliven global literary
culture.
D. Currell (*)
I. Issa
The nature and timeliness of Digital Milton also validate Lauren Klein
and Matthew Gold’s assessment in the 2016 edition of Debates in the
Digital Humanities, that “the challenges currently associated with the
digital humanities involve a shift from congregating in the big tent to
practicing DH at a field-specific level, where DH work confronts disciplin-
ary habits of mind.”13 The “big tent” has been a longstanding metaphor
in digital humanities circles.14 It is a reassuringly irenic image. It may
recall:
One would have to have a core of silicon to process the death of Little Nell
without laughing. As the chapters by David Ainsworth, Olin Bjork and
John Rumrich, Issa, and Cordelia Zukerman exemplify, this collection is
specially charged with concern for the mechanisms whereby the digital can
engender ideational, hermeneutic, generative, and productive encounters
with Milton. Even where they leverage algorithmic criticism or data visu-
alization, the stakes ultimately lie in those encounters.
The close/“distant” false dichotomy is partly a symptom of the wide-
spread treatment of Moretti and the Stanford Literary Lab, one of the
highest-profile practitioners and best-funded centers, as normative or even
representative of the digital humanities. It is a limitation of the first chap-
ter of Tom Eyers’ stimulating Speculative Formalism.26 Drucker’s history
of scholarly, poetic, and artistic practice, including the theoretical and
experimental work that, along with McGann and Bethany Nowviskie, she
pursued under the rubric of “speculative computing,” could productively
complement and complicate Eyers’ narrow critique of DH.27 An ethos of
speculative computing and a version of speculative formalism may in prac-
tice prove to be allies against any “new positivism.” David Currell’s chap-
ter on the Miltonic verse line proposes a confluence of critical formalism
and digital formats, while Basu’s algorithmic processing of the EEBO-
TCP explores how form, information, and format might be computed
through big data.
MILTON! THOU SHOULDST BE LIVING IN THESE MEDIA 7
questions about the afterlives of texts and the present lives of people,
including the question of to whom the wish for present life—at this hour,
in these media—is extended.
Notes
1. Julia Thompson Klein, Interdisciplining Digital Humanities: Boundary
Work in an Emerging Field (Ann Arbor: University of Michigan Press,
2015), 2.
2. John Milton, Areopagitica (1644), in The Complete Prose Works of John
Milton, ed. Don M. Wolfe et al., 8 vols. (New Haven: Yale University
Press, 1953–82), 2: 515.
3. Milton, Areopagitica, in Complete Prose Works, 2: 492.
4. Exceptions include Laura Lunger Knoppers and Gregory M. Colón
Semenza, eds., Milton in Popular Culture (New York: Palgrave Macmillan,
2006), containing Bruno Lessard, “The Environment, the Body, and the
Digital Fallen Angel in Simon Biggs’s Pandaemonium,” 213–24, and
Thomas H. Luxon, “Milton and the Web,” 225–36; and Peter C. Herman,
ed., Approaches to Teaching Milton’s Paradise Lost, 2nd ed. (New York:
Modern Language Association, 2012), containing Peter C. Herman,
“Audiovisual and Online Aids,” 9–11, and Thomas H. Luxon, “The John
Milton Reading Room: Teaching Paradise Lost with an Online Edition,”
189–91.
5. For an exception, see David L. Hoover’s chapter in the 2016 Debates in the
Digital Humanities, which rebuts the framing and example (concerning
Areopagitica) used by Stanley Fish in a New York Times piece that endeav-
ored to cloister Milton from digital literary studies. David L. Hoover,
“Argument, Evidence, and the Limits of Digital Literary Studies,” in
Debates in the Digital Humanities, ed. Lauren F. Klein and Matthew
K. Gold (Minneapolis: University of Minnesota Press, 2016) <dhdebates.
gc.cuny.edu/debates/text/71>. Accessed 15 December 2017.
6. See, for example, Alan Galey and Ray Siemens, eds., “Reinventing Digital
Shakespeare,” spec. issue of Shakespeare 4, no. 3 (2008); Hugh Craig and
Arthur F. Kinney, eds., Shakespeare, Computers, and the Mystery of
Authorship (Cambridge: Cambridge University Press, 2009); Thomas
Dipiero and Devoney Looser, eds., “The Digital Turn,” spec. issue of
Journal of Early Modern Cultural Studies 13, no. 4 (2013); Christie Carson
and Peter Kirwan, eds., Shakespeare and the Digital World: Redefining
Scholarship and Practice (Cambridge: Cambridge University Press, 2014);
Brett D. Hirsch and Hugh Craig, eds. “Digital Shakespeares,” spec. issue
of The Shakespearean International Yearbook 14 (2014); Laura Estill,
16 D. CURRELL AND I. ISSA
Diane K. Jakacki, and Michael Ullyot, eds., Early Modern Studies after the
Digital Turn (Toronto: Iter Press, 2016); Hugh Craig and Brett Greatley-
Hirsch, eds., Style, Computers, and Early Modern Drama: Beyond Authorship
(Cambridge: Cambridge University Press, 2017); and a projected special
issue of the journal Humanities on “Shakespeare and Digital Humanities.”
7. Rachel Trubowitz, “Introduction,” in Milton and the Politics of
Periodization, ed. Rachel Trubowitz, spec. issue of MLQ 78, no. 3 (2017):
291–99 (291).
8. Trubowitz, “Introduction,” 291.
9. Trubowitz, “Introduction,” 292. See also in this connection Tom Eyers’
provocative but reductive positing of digital humanities (dubbed “The
New Positivism”) and Greenblattian New Historicism as secret intellectual
bedfellows, at least in their model of history, against both of which he
stages a return to formalism and deconstruction in Speculative Formalism:
Literature, Theory, and the Critical Present (Evanston, IL: Northwestern
University Press, 2017), 42–48.
10. Blaine Greteman, “Milton and the Early Modern Social Network: The Case
of the Epitaphium Damonis,” Milton Quarterly 49, no. 2 (2015): 79–95;
Whitney Anne Trettien, “A Deep History of Electronic Textuality: The Case
of English Reprints Jhon Milton Areopagitica,” Digital Humanities Quarterly
7, no. 1 (2013), <digitalhumanities.org/dhq/vol/7/1/000150/000150.
html>. Accessed 17 November 2017; Christopher Warren et al., Six Degrees
of Francis Bacon (2017), Carnegie Mellon University Libraries, <sixde-
greesoffrancisbacon.com>. Accessed 1 December 2017. See also Daniel
Shore, Cyberformalism: Histories of Linguistic Forms in the Digital Archive
(Baltimore: Johns Hopkins University Press, 2018), which appeared as the
current collection entered production.
11. Jerome McGann, A New Republic of Letters: Memory and Scholarship in the
Age of Digital Reproduction (Cambridge, MA: Harvard University Press,
2014), 4.
12. Jerome McGann, “Philology in a New Key,” Critical Inquiry 39, no. 2
(2013): 327–46.
13. “Digital Humanities: The Expanded Field,” in Debates in the Digital
Humanities, ed. Lauren F. Klein and Matthew K. Gold (Minneapolis:
University of Minnesota Press, 2016) <dhdebates.gc.cuny.edu/debates/2>.
Accessed 15 December 2017.
14. In a keynote lecture reprinted as the preface to a major DH anthology, Ray
Siemens elaborates upon the kinds of recurrent conversations within and
about the DH community’s “Big Tent”: “Here, we talk about remediating
old worlds and extant material artifacts, we talk about working with new
ones that are created with the technologies we use, and we talk about
embracing enlarging scope, privileging diversity within that embrace and
privileging public outreach and engagement. Here we talk also about
MILTON! THOU SHOULDST BE LIVING IN THESE MEDIA 17
earlier posts and links (not all functional) remain available (accessed 1
December 2017).
42. “The Milton-L Archives” (2003–), University of Richmond, <lists.rich-
mond.edu/pipermail/milton-l>. Accessed 1 December 2017.
43. The Milton Society of America (2018), CUNY Academic Commons, <mil-
tonsociety.commons.gc.cuny.edu>. Accessed 1 January 2018.
44. Compare Marvell’s “On Paradise Lost,” printed in the second edition of
Milton’s poem: “While the town-Bayes writes all the while and spells, /
And like a pack-horse tires without his bells: / Their fancies like our bushy-
points appear, / The poets tag them, we for fashion wear” (ll. 47–50,
quoted from Paradise Lost, ed. Fowler, 54). “Bayes” is an allusive hit at the
laureate Dryden, whose unperformed operatic adaptation of Paradise Lost
used rhyming couplets.
Works Cited
Brown, Brian A. “Primitive Digital Accumulation: Privacy, Social Networks, and
Biopolitical Exploitation.” Rethinking Marxism: A Journal of Economics,
Culture, and Society 25, no. 3 (2013): 385–403.
Campbell, Gordon, Thomas N. Corns, John K. Hale, and Fiona J. Tweedie.
Milton and the Manuscript of De Doctrina Christiana. Oxford: Oxford
University Press, 2007.
Carson, Christie and Peter Kirwan, eds. Shakespeare and the Digital World:
Redefining Scholarship and Practice. Cambridge: Cambridge University Press,
2014.
Corns, Thomas N. The Development of Milton’s Prose Style. Oxford: Clarendon
Press, 1982.
———. Milton’s Language. Oxford: Blackwell, 1990.
Craig, Hugh and Arthur F. Kinney, eds. Shakespeare, Computers, and the Mystery of
Authorship. Cambridge: Cambridge University Press, 2009.
Craig, Hugh and Brett Greatley-Hirsch, eds. Style, Computers, and Early Modern
Drama: Beyond Authorship. Cambridge: Cambridge University Press, 2017.
Creamer, Kevin J. T. 2007–. “About.” John Milton: The Milton-L Home Page.
<johnmilton.org/about>. Accessed 1 December 2017.
———. 1991–2009. The Milton-L Home Page. <facultystaff.richmond.
edu/~creamer/milton>. Accessed 1 December 2017.
Danielson, Dennis. Paradise Lost and the Cosmological Revolution. Cambridge:
Cambridge University Press, 2014.
Dipiero, Thomas and Devoney Looser, eds. The Digital Turn. Special issue of
Journal of Early Modern Cultural Studies 13, no. 4 (2013).
Drucker, Johanna. SpecLab: Digital Aesthetics and Projects in Speculative
Computing. Chicago: University of Chicago Press, 2009.
MILTON! THOU SHOULDST BE LIVING IN THESE MEDIA 21
———. “Why Distant Reading Isn’t.” PMLA 132, no. 3 (2017): 628–35.
Estill, Laura, Diane K. Jakacki, and Michael Ullyot, eds. Early Modern Studies
After the Digital Turn. Tempe, AZ: Arizona Center for Medieval and
Renaissance Studies, 2016.
Eyers, Tom. Speculative Formalism: Literature, Theory, and the Critical Present.
Evanston, IL: Northwestern University Press, 2017.
Fletcher, Katharine, et al., eds. 2008–. Darkness Visible. Christ’s College,
Cambridge University. <darknessvisible.christs.cam.ac.uk/index.html>.
Accessed 1 December 2017.
Galey, Alan and Ray Siemens, eds. “Reinventing Digital Shakespeare.” Special
issue of Shakespeare 4, no. 3 (2008).
Gilman, Ernest B. “Milton and the Mac: ‘Inwrought with Figures Dim.’” In So
Rich a Tapestry: The Sister Arts and Cultural Studies, edited by Ann Hurley and
Kate Greenspan. Lewisburg, PA: Bucknell University Press, 1995. 336–55.
Golumbia, David. “Death of a Discipline.” Differences: A Journal of Feminist
Cultural Studies 25, no. 1 (2014): 156–76.
Greteman, Blaine. “Milton and the Early Modern Social Network: The Case of the
Epitaphium Damonis.” Milton Quarterly 49, no. 2 (2015): 79–95.
Herman, Peter C., ed. Approaches to Teaching Milton’s Paradise Lost. 2nd ed.
New York: Modern Language Association, 2012.
Hirsch, Brett D., and Hugh Craig, eds. “Digital Shakespeares.” Special issue of
The Shakespearean International Yearbook 14 (2014).
Hoover, David L. “Argument, Evidence, and the Limits of Digital Literary
Studies.” In Debates in the Digital Humanities, edited by Lauren F. Klein and
Matthew K. Gold. Minneapolis: University of Minnesota Press, 2016.
<dhdebates.gc.cuny.edu/debates/text/71>. Accessed 15 December 2017.
Jockers, Matthew L. Macroanalysis: Digital Methods and Literary History. Urbana:
University of Illinois Press, 2013.
“John Milton’s Paradise Lost.” 2008. Online Exhibition. The Morgan Library and
Museum. <themorgan.org/collection/John-Miltons-Paradise-Lost>. Accessed
1 December 2017.
Klein, Julie Thompson. Interdisciplining Digital Humanities: Boundary Work in
an Emerging Field. Ann Arbor: University of Michigan Press, 2015.
Klein, Lauren F. and Matthew K. Gold. “Digital Humanities: The Expanded
Field.” In Debates in the Digital Humanities, edited by Lauren F. Klein and
Matthew K. Gold. Minneapolis: University of Minnesota Press, 2016.
<dhdebates.gc.cuny.edu/debates/2>. Accessed 15 December 2017.
Knoppers, Laura Lunger and Gregory M. Colón Semenza, eds. Milton in Popular
Culture. New York: Palgrave Macmillan, 2006.
Kolbrener, William. Milton’s Warring Angels: A Study of Critical Engagements.
Cambridge: Cambridge University Press, 1997.
22 D. CURRELL AND I. ISSA
Lessard, Bruno. “The Environment, the Body, and the Digital Fallen Angel in
Simon Biggs’s Pandaemonium.” In Milton in Popular Culture, edited by Laura
Lunger Knoppers and Gregory M. Colón Semenza. New York: Palgrave
Macmillan, 2006. 213–24.
Luxon, Thomas H. “Milton and the Web.” In Milton in Popular Culture, edited
by Laura Lunger Knoppers and Gregory M. Colón Semenza. New York:
Palgrave Macmillan, 2006. 225–36.
———. “The John Milton Reading Room: Teaching Paradise Lost with an Online
Edition.” In Approaches to Teaching Milton’s Paradise Lost, edited by Peter
C. Herman. 2nd ed. New York: Modern Language Association, 2012. 189–91.
McGann, Jerome. A New Republic of Letters: Memory and Scholarship in the Age of
Digital Reproduction. Cambridge, MA: Harvard University Press, 2014.
———. “Philology in a New Key.” Critical Inquiry 39, no. 2 (2013): 327–46.
Milton, John. The Complete Prose Works of John Milton, edited by Don M. Wolfe
et al. 8 vols. New Haven: Yale University Press, 1953–82.
———. Paradise Lost, edited by Alistair Fowler. 2nd ed. Harlow, UK: Longman,
1997.
The Milton Society of America. 2018. CUNY Academic Commons. <miltonsociety.
commons.gc.cuny.edu>. Accessed 1 January 2018.
“The Milton-L Archives.” 2003–. University of Richmond. <lists.richmond.edu/
pipermail/milton-l>. Accessed 1 December 2017.
Moretti, Franco. “Conjectures on World Literature.” New Left Review, n.s. 1
(2000): 54–68.
———. Distant Reading. London: Verso, 2014.
———. Graphs, Maps, Trees: Abstract Models for a Literary Theory. London: Verso,
2005.
Mullins, Brody and Jack Nicas. “Paying Professors: Inside Google’s Academic
Influence Campaign.” The Wall Street Journal. 14 July 2017.
Picciotto, Joanna. Labors of Innocence in Early Modern England. Cambridge, MA:
Harvard University Press, 2010.
Preston, Claire. The Poetics of Scientific Investigation in Seventeenth-Century
England. Oxford: Oxford University Press, 2015.
Raben, Joseph. “A Computer-Aided Study of Literary Influence: Milton to
Shelley.” In Literary Data Processing Conference Proceedings, edited by Jess
B. Bessinger, Jr., Stephen M. Parrish, and Harry F. Arader. New York: Modern
Language Association, 1964. 230–74.
Shore, Daniel. Cyberformalism: Histories of Linguistic Forms in the Digital Archive.
Baltimore: Johns Hopkins University Press, 2018.
Siemens, Ray. “Preface: Communities of Practice, the Methodological Commons,
and Digital Self-Determination in the Humanities.” In Doing Digital
Humanities: Practice, Training, Research, edited by Constance Crompton,
Richard J. Lane, and Ray Siemens. London: Routledge, 2016. xxi–xxxiii.
MILTON! THOU SHOULDST BE LIVING IN THESE MEDIA 23
Textual Remediations
CHAPTER 2
Cordelia Zukerman
In 1996, years before the term “digital humanities” had any currency,
Thomas H. Luxon, a professor at Dartmouth College, New Hampshire,
had an idea for a new teaching edition of Paradise Lost.1 Since his students
often felt “hopelessly unlearned” in the face of John Milton’s extensive
and varied textual allusions, Luxon thought of teaching his Milton course
in the campus library, where he could send student runners to retrieve
books from the stacks when the need arose during class discussion.2 As he
considered this idea, he realized he could achieve the same effect by using
virtual runners in virtual stacks: by developing an online edition of Paradise
Lost containing hyperlinks and annotations that would allow students to
engage productively with Milton’s allusions. Luxon soon began construct-
ing a website, which he named The John Milton Reading Room, a name
that suggests a space in which people come together to find and read
books. Now past its 20th year, the Milton Reading Room, which aims to
put all of Milton’s works online, has existed for almost as long as the mod-
ern Internet itself—and, like the Internet, has developed over time. As one
of the most comprehensive digital editions of an early modern author’s
C. Zukerman (*)
works and the only born-digital edition of Milton’s works, the Milton
Reading Room can show us how much Milton studies has to gain by
embracing the digital age.
Two important factors made it possible to create the Milton Reading
Room as a born-digital edition. First, Luxon believed that the problem he
sought to answer—how to make Milton’s allusions accessible for stu-
dents—could be solved more effectively through digital tools than any
other available resources. Second, Luxon’s institution, Dartmouth
College, was one of the premier university campuses for academic comput-
ing.3 Luxon was therefore in a privileged—and, in 1996, relatively rare—
position not only to imagine the possibilities for a digital edition of Milton,
but also to realize them. Luxon partnered with Sarah Horton, an instruc-
tional designer at Dartmouth’s Department of Academic Computing, to
design the site; since then, he has worked regularly with collaborators from
the Dartmouth computing community to update it.4 From its inception,
the Milton Reading Room’s editorial apparatus has aimed to show, rather
than tell. As Luxon has written, “Instead of snowing students with refer-
ences to things they have never read, the Milton Reading Room’s annota-
tions take them to the relevant texts and allow them to read enough to
begin drawing conclusions and forging research plans.”5 This process of
pointing students to resources rather than telling them what they are sup-
posed to find there is, Luxon asserts, the immense benefit of an online
edition of a text.6 The Milton Reading Room uses its digital platform to
encourage readers to think of themselves not as passive receivers of infor-
mation, but as active users of the site and its many research tools and
hyperlinks—as “Authors to themselves in all / Both what they judge and
what they choose” (Paradise Lost 3.122–23).7 In this way, the site encour-
ages readers at all levels to participate productively in Milton scholarship.
In recent years, scholarly conversations about digital editing have often
centered on the changing role of the reader in the new digital environ-
ment. A key feature of born-digital texts, as Patrick Sahle articulates, is
that they “can not be printed without a loss of information and/or func-
tionality.”8 This shift from the “two-dimensional space of the ‘page’” to a
more complex series of digital paths creates the possibility for a non-linear
reading experience.9 Some scholars believe that digital formats therefore
“impel[] new reading habits.”10 Others go so far as to claim that “digital
media” may “initiate a new kind of literacy.”11 This change happens, as
Daniel Apollon, Claire Bélisle, and Philippe Régnier assert, because digital
THE JOHN MILTON READING ROOM 29
among other things, each edition’s level and type of modernization; the
quality, content, and ease of reading footnotes; the selection of texts
within collected editions; and the price of each edition. Each text emerges
as having certain benefits and certain drawbacks. It would seem that an
ideal teaching text of Milton’s works would invite those who wanted to
engage in specialized study to do so, while offering resources to those who
might feel overwhelmed by the varied challenges posed by the text.
Herman’s overview of available editions contains no such printed edition,
since printed texts cannot easily operate with this kind of duality.
Editors of early modern works have sought in recent years to develop
new methods for presenting duality or multiplicity in scholarly and teach-
ing texts.21 Most acknowledge, however, that doing so in print has its
drawbacks—most often in readability or price. While some use side-by-side
presentation or extensive annotations, these choices can muddle a reading
and teaching text. Dobranski has articulated the challenges of these
approaches by calling for an edition of Milton that points readers to
important moments for critical engagement without overwhelming them:
“If good editing, like a musical accompaniment, ought to enhance with-
out overpowering, to render intelligible without calling attention to itself,
then modern editors must not emend or annotate a text so intrusively that
it becomes distorted or cluttered.”22 Unable to conceive of a print text
that would accomplish these goals, he advocates “exploring new forms of
online publication.”23 Digital editions allow for ambiguity to a far greater
extent than printed texts: with a digital edition, an ambiguous word or
moment can be both/and, rather than either/or.
Indeed, digital editions make it possible to achieve editorial formats
that were only previously possible in theory.24 Experimental digital proj-
ects, such as Bernice W. Kliman’s online Enfolded Hamlet, Jesús Tronch’s
proposed “hypertextual, multilingual” edition of Hamlet, or Marina
Buzzoni’s multiframe visualization of the “two major witnesses” of the
Old Saxon poem Hêliand, enable new options for viewing multiple textual
variants and translations side by side.25 Such projects show how editors are
embracing the opportunities offered by digital formats to allow readers to
engage productively with different kinds of ambiguity. As Terje Hillesund
and Claire Bélisle assert, “The flexibility of digital texts, such as in digital
scholarly editions, also allows users to constantly rearrange text, use mul-
tiple windows and multiple media, bring in external resources, and manip-
ulate the appearances of the text, such as the layout and font properties.”26
This helps readers become active participants in the reading experience,
32 C. ZUKERMAN
input if they choose, but are not asked to construct the reading text them-
selves. The primary objective of the Milton Reading Room is to help
reader-users discover and pursue avenues for further research, and its
design is compatible with that objective.
In keeping with his philosophy that students should be considered spe-
cialists in training, Luxon uses a light editorial touch when it comes to
modernization: he aligns each text placed on the site with a specific early
modern edition of Milton’s works—spelling, punctuation, and all.35
Creaser has argued that such a choice minimizes the editor’s role and
makes the reading process more difficult for students.36 However, Luxon’s
edition follows the theory—seconded by Dobranski—that students strug-
gle with Milton’s textual allusions far more than they struggle with early
modern spelling and punctuation.37 Therefore, rather than focusing on
modernization and textual variants, Luxon provides an editorial apparatus
that encourages students and scholars alike to read Milton’s works criti-
cally and engage widely with his varied allusions.
In its formatting and annotations, the Milton Reading Room achieves a
textual apparatus that print texts simply cannot. Luxon initially conceived
it as a multipart format in which readers could just as easily read Milton’s
works straight through as they could find and read annotations along the
way. In its early years, the site was designed to have separate frames that
readers could scroll through at their own pace: one frame for Milton’s
works, and one for the annotations. Readers could click on a hyperlink in
Milton’s text, and the annotation frame would move to the corresponding
note. The site has since been redesigned as a single frame in JavaScript to
make it more aesthetically pleasing and more accessible on phones and
tablets, which now make up a significant portion of the user platforms.38
However, the principles remain the same: it is possible either to read
Milton’s text uninterrupted, or to click on any hyperlink to reveal the cor-
responding note in the otherwise empty space to the right of the text.
The Milton Reading Room solves the spelling question through a
design only possible on the Internet: readers can hover the cursor over
words to reveal elongations of abbreviated words such as “fall’n” and
“th’” and modernizations of archaic forms such as “beest,” “dost,” and
“durst” (Paradise Lost 1.84, 15, 84, 17, 49). This design allows Luxon to
retain the early modern orthography, with all its rhythms and resonances,
while also giving contemporary readers the tools to recognize every word.
The text can therefore reach different kinds of readers, ranging from spe-
cialist to beginning student: those who choose to ignore the modernizations
Another random document with
no related content on Scribd:
CONGESTION OF THE LIVER IN THE
HORSE.
Causes. Beside the general causes above mentioned, may be
specially named, musty, decomposed, and irritant fodders: those
which like green legumes, are easily fermented; and those which
contain stimulating volatile oils or carminative principles. They are
also especially exposed to such causes as severe and prolonged work
under a hot sun, the nervous atony which causes vaso-dilatation in a
hot climate, and such traumatisms as come from falls, kicks, goring,
and blows by shafts, poles and clubs. These especially induce active
congestion. The passive forms come mainly from obstruction in the
lungs, or heart (dilatation, right valvular insufficiency, pericarditis,
hydropericardium, myocarditis, fatty degeneration, endocarditis), or
in the posterior vena cava.
Lesions. The congested liver is enlarged and deeply colored with
blood. The weight of twenty to thirty pounds is often attained. While
the color is of a deep red throughout, there are spots of a still darker
hue indicating the seat of subcapsular or deeper seated hemorrhages.
The color varies according as the congestion is passive or active. In
the former the coloration is deeper in the centre of the acinus
(nutmeg liver) indicating congestion of the hepatic veins, while in the
latter the periphery of the acinus may be most deeply stained
implying congestion of the portal vein. The consistency of the organ
is diminished, and the more acute the attack the greater the friability.
In such cases there is a parboiled appearance indicating granular and
commencing fatty degeneration. Under the microscope the relative
distension of the intralobular, and interlobular veins and the hepatic
capillaries becomes more distinctly marked and the presence of
pigment and fatty granules and the lack of protoplasm and nuclei in
the hepatic cells indicate their progressive changes. When the
peripheral cells are pale from fatty granules the contrast between the
light margin and dark centre of the acinus, makes the mottled or
nutmeg aspect of the liver much more pronounced.
In old standing cases of passive congestion the liver may be the
seat of fibroid degeneration, extending from the capsule inward in
bands or trabeculæ, and giving to the organ a firm resistant character
(sclerosis, cirrhosis).
Symptoms. The symptoms are general and suggestive rather than
pathognomonic. There are dullness, prostration, unsteady walk,
pendent head, with occasional jerking, semi-closed eyes, redness of
the conjunctiva, slight colicy pains, arching of the loins, muscular
tremblings and decubitus on the left side rather than the right. The
more definite symptoms are tenderness on percussion with the
closed fist over the last ribs (the liver) especially on the right side,
increase of the area of hepatic percussion dullness (which may be
rendered valueless by a loaded colon), the presence of a slight icterus
in the conjunctiva and urine, and an increase of the urine secreted
and an excess of the contained urea.
In passive cases however the obstruction to the escape of blood
from the liver prevents the development of icteric symptoms, of
uræmia and of polyuria. In all such cases however there follows a
general congestion of the portal system and if it persists for any
length of time gastro-intestinal congestion and catarrh and even
ascites may develop.
In all cases alike the history of the attack will help towards a
satisfactory diagnosis.
Prevention. A rational hygiene embracing daily work or exercise,
moderate laxative diet, green food in its season, pure cool air are
important precautions.
Treatment. A moderate supply of green or laxative food, the
withholding for the time of grain, and especially of maize, wheat or
buckwheat, saline laxatives daily, and a stimulating embrocation or
blister to the tender hypochondrium are the most important
measures. Exercise in a box stall, or still better in a yard or paddock
in the intervals between more systematic work forms an important
adjunct to medicine. As a laxative sulphate of soda is to be preferred
at first in a full cathartic dose and later in a daily amount sufficient to
relax the bowels. Given in a bucket of water every morning before the
first meal a very small dose will be effective.
CONGESTION OF THE LIVER IN THE DOG.
Active congestion is very rare excepting in over-fed and indolent
family pets. Passive congestion induced by diseases of the lungs and
heart is however far from uncommon.
Lesions. True to their origin these usually appear as the spotted
nutmeg liver with the deep congestion in the centre of the acini. For
the same reason the fibroid degenerations shown in chronic cases,
show the firm fibroid neoplasm chiefly around the hepatic veins.
Granular, fatty and pigmentary degeneration of the cells are found as
in the solipeds.
Symptoms. These are as obscure as in the horse. There is always a
history of a sluggish, gourmandizing life, and in the early stages, a
manifestation of embonpoint which suggests a torpid liver. Further
suggestions may also be obtained from coexisting diseases of the
lungs, or heart, from gastro-intestinal catarrh, from piles, or ascites.
Then there is at times a slight icterus of the conjunctiva and urine.
Finally tenderness on percussion on the right hypochondrium,
decubitus on the left side, and an increased area of dullness on
percussion may afford useful hints for diagnosis.
Treatment. In the rare cases due to infection from the intestine, an
active saline purgative followed by antiseptics (salol, naphthalin,
naphthol, etc.,) daily will be of value. It is also desirable to keep up
the action of the bowels by morning doses of salines. In cases
consequent on chest disease attention must be given to such primary
trouble. In all cases a restricted laxative diet, and graduated but
increasing exercise in the open air are demanded.
HEPATIC HÆMORRHAGE OR RUPTURE.
Causes: Mechanical injuries, falls, blows, kicks, degenerations, amyloid, fatty,
granular, congestion, neoplasms, glanders, tuberculous, myomatous, microbian
infection. In the horse, disease of liver, heart, lungs, hepatic artery, portal vein,
degenerations following overfeeding, idleness, foreign bodies, arsenic, phosphorus,
parasites, violent movements in colic, running, draught, leaping. In the dog,
pampering and traumatism. In cattle forced feeding, emaciation, microbian
infection. In birds, tubercle, tæniasis, microbian infection. Lesions: extravasation,
intracapsular, or through capsule into the peritoneal cavity. The extravasation
bulges of a deep black, covering a dark softened, pulpy, hepatic tissue, with light
colored fatty tissue around. Clots may be stratified from successive bleedings. Liver
usually enlarged. Symptoms: onset sudden, or preceded by stiffness, soreness and
other signs of hepatic trouble. Extensive rupture, entails weakness, unsteady gait,
perspiration, pallor of mucosæ, small weak rapid pulse, palpitations, dilated
pupils, rolling eyes, amaurosis, tremors, convulsion in case of survival, coldness,
œdemas. Death in five hours to five days. Risk of relapse in recovering cases.
Treatment: rather hopeless, rest, laxative, ergot, ferric chloride, tannic acid, witch
hazel, cold water, snow or ice to right side. In meat producing animals fatten.
Causes. Hemorrhage and rupture of the liver are closely correlated
to each other, the accumulation of extravasated blood in the
parenchyma in the one case leading to over distension of the capsule,
and the laceration of this capsule and of the adjacent substance of
the liver occurring in the other as a mere extension of the first. They
usually occur as the direct result of mechanical injury (falls, blows,
kicks) acting on a liver already softened and friable through disease.
These predisposing degenerations may be amyloid (Caparini, Johne,
Rabe), fatty (Julien, Gowing, Adam, Siedamgrotzky), granular
softening, hepatitis or congestion (Zundel), glander neoplasms
(Mathis), tubercles, angiomata (Trasbot), microbian infection
(Stubbe), tumors (Brückmüller).
In the horse predisposing conditions may be found in diseases of
the liver, heart or lungs, in embolism of the hepatic artery (Wright),
in obstruction of the portal vein (Pierre), in infarction of the liver, in
degeneration with softening, in sarcomatous, melanotic, glanderous
or cancerous deposits in its substance, in degenerations consequent
on over feeding, idleness, congestions, on the penetration of husks of
grains into the liver substance, on arsenical or phosphorus
poisoning. The presence of flukes, echinococci and other parasites
may also cause congestion and softening. To the immediate or
traumatic causes above named may be added the violent movements
attendant on a severe attack of colic, and violent exertions in
running, draught, leaping, etc. (Friend).
In the dog we must recognize all the pampering conditions which
predispose to congestion and degeneration, together with more
direct operation of kicks, blows, falls, fights, over exertion, etc.
In cattle a forcing regimen is especially predisposing, and yet the
loss of vigor resulting from a diametrically opposite treatment, must
be accepted as an occasional cause. Stubbe found in emaciated cows
miliary hemorrhagic infarcts of a dark red color which gradually
extended to an inch or more in diameter. These he traced to
microbian infection coming by way of the chronic intestinal lesions
which are common in old cows. The final result of such infarctions
was loss of hepatic substance and the formation of cicatricial tissue
with a marked depression on the surface of the organ.
In birds fatal hepatic hemorrhages occur in connection with local
tubercle (Cadiot), tæniasis of the liver, or microbian infection.
Lesions. The hemorrhage may take place into the substance of the
liver only, or the capsule may be lacerated so that the blood escapes
into the peritoneal cavity in considerable quantity.
In the horse it usually occurs in the right or middle lobe, rarely in
the left. There may be one or more hemorrhagic effusions varying in
size from a cherry to a duck’s egg, or even an infants’ head (Lorge).
This projects from the surface of the organ and its deep black
contrasts strongly with the white of the adjacent capsule. When laid
open the hepatic tissue is seen to be softened and pulpy, and its dark
color forms a striking contrast with any surrounding fatty liver. Any
form of degeneration may be revealed on microscopic or chemical
examination. Not unfrequently small clots of blood form under the
capsule raising it in the form of little sacs. Such clots are usually
stratified indicating a succession of small hemorrhages.
When the capsule is torn, the lesion may extend from one surface
of the organ to the other, and the edges, smooth, uneven or fringed,
are united together by a blood clot.
In case of hemorrhagic infarcts the lesion usually has a distinctly
conical outline corresponding to the vascular distribution. These are
especially characteristic of cases supervening on heart disease.
The volume of the liver is usually increased and the weight may
reach 30 lbs. (Schmeltz), 34 lbs. (Lorge), or even 66 lbs. (Trasbot).
In other domestic animals analogous lesions are found modified
largely according to the size of the subject.
Symptoms. These may develop instantaneously without any
marked premonitory indication. In other cases tenderness on
percussion over the liver, stiffness or groaning under sudden
movements or turning, arching of the back, hanging of the head,
slowness in rising, costiveness, slight transient colics, and even
icterus may have been detected on close observation. The symptoms
of actual rupture are essentially those of internal hemorrhage. The
animal becomes weak, or unsteady upon its limbs, perspires, arches
the back, and shows a marked pallor of the visible mucosæ. The
pulse is small, thready, weak and accelerated, and the heart beats
violent or palpitating. The percussion dullness over the liver is
extended (Weber), the loins become insensible to pinching, and
there may be some distension of the abdomen. Dilatation of the
pupils, retraction or rolling of the eyes, amaurosis, tremors of the
muscles of the neck, lying down, or falling, and general convulsions
may precede death. This may occur in a few hours or it may be
delayed if the lesions are restricted. In case of survival, coldness and
œdema of the extremities and sheath have been observed. The lesser
hemorrhages may terminate in recovery if there is no attendant
incurable disease. In anthrax, glanders, cancer, tuberculosis,
septicæmia, etc., a favorable issue is not to be looked for.
Duration. Termination. In severe cases a fatal issue may be
expected in from five hours to five days. In the milder cases which
make a temporary recovery there is great danger of a second
hemorrhage from the new vessels in the tissue undergoing
organization or from the adjacent degenerate liver tissue. The course
of the affection may be altered by such complications as arthritis
(Dieckerhoff), pneumonia, pulmonary thrombosis (Leblanc),
enteritis or peritonitis (Cadeac).
Treatment is usually of no avail. Rest, and the administration of
laxatives and hæmostatics, have been especially recommended. Of
the latter, ergot by the mouth or ergotin subcutem, tends to
contraction of the blood-vessels and to check the flow. Ferric
chloride is also used, though apt to interfere with hepatic function.
Tannic acid, hamamelis, and other astringents may be used instead.
Cold water, snow or ice applied to the right hypochondrium may act
as a check to the hemorrhage. Unless in purely traumatic cases in an
otherwise healthy liver, a recovery is at best temporary, and the
already degenerate liver is liable to relapse at any moment. In horses
and dogs, therefore, recovery is by no means an unmixed good. Meat
producing animals that recover should be prepared for the butcher.
HEPATITIS.
Forms of hepatitis: Parenchymatous hepatitis. Definition: Degeneration of
hepatic cells. Relation to enteritis and nephritis. In horse—causes:—as in
congestion, pampering, spoiled fodder, malt, inundated meadows, chill,
overfeeding, hot moist climate, hæmoglobinæmia, infection. In cattle—causes:—
forcing ration, hot weather, overwork, infection. In dog—causes:—infection from
alimentary canal. Lesions: Enlarged, softened liver, round edges, a week later
yellow atrophy, granular on section, bloodless. Acini with indefinite margins, cells
granular, nuclei lost. In dog centres of softening. Symptoms:—in horse: Attack
sudden, rigor, fever, dullness, prostration, yellowish red mucosæ, unsteady gait,
slight colic, anorexia, urine decreased, glairy, brownish red, groaning in defecation,
excited circulation and breathing, increased icterus by third day, fœtid, colorless
diarrhœa. Diagnosis: Coincidence of fever, prostration, icterus, painful defecation,
fœtid diarrhœa, light color of stools, tenderness and flatness on percussing hepatic
area. From influenza by absence of watering eyes and contagion. Prognosis in
horse: Very grave unless urine is free. Treatment in horse: Portal depletion,
calomel, ipecacuan, salines, diuretics, fomentation of loins, antiseptics, derivatives,
mineral acids, bitters. Careful laxative diet in convalescence. Symptoms in cattle:
Slower onset, anorexia, dullness, depression, drivelling saliva, grinding teeth,
icterus, constipation, later fœtid diarrhœa, pale colored stools, recumbency, groans
on rising, arching back, tender right hypochondrium, fever. Prognosis grave. Death
in five to six days. Treatment as in horse: Only saline laxatives. Symptoms in dog:
Muscular tremors, staring coat, hyperthermia, icterus, fœtid breath, ventral
decubitus, extreme prostration, anorexia, tender right hypochondrium, diminished
urine, death in two or three days. Treatment in dog: Calomel and jalap, diuretics,
laxatives, derivatives, germicides, in convalescence, mineral acids, bitters, careful
diet.
The different forms of inflammation of the liver are distinguished
according as they affect, especially the hepatic cells and tissue of the
acini (parenchymatous), as they result in suppuration (suppurative,
catarrhal, abscess), as they cause necrobiosis in nodular masses
(infectious or necrotic), as they lead to fibroid thickening under the
peritoneum and proper capsule (perihepatitis); or as they cause
general fibroid induration of the organ by increase of its connective
tissue (cirrhosis).
PARENCHYMATOUS HEPATITIS, ACUTE
YELLOW ATROPHY OE THE LIVER.
The characteristic morbid lesion in this disease is the degeneration
of the liver cells, loss of their protoplasm and nuclei and of their
normal functions. It may be circumscribed to limited areas, or may
affect the liver, generally. As the hepatic functions, are so intimately
related to those of the bowels and kidney, the affection is usually
accompanied by inflammations of these organs as well.
Causes in horses. The same general causes which produce
congestion, may also determine the further morbid stage of
inflammation. Cadeac mentions a case which developed in a horse
kept alone and idle in the stable. He makes no mention of condition,
food, cleanliness nor ventilation. Haubner and Franzen have traced it
to a diet of malt or of hay harvested from inundated meadows.
Zundel records a case following exposure to extreme cold. More
commonly the disease is secondary to the overtaxing of the liver, by
heavy feeding in warm moist climates, or in hæmoglobinæmia, or to
the arrest of the micro-organisms of the food, or of infectious
diseases.
Causes in Cattle. These suffer rarely, but from essentially the same
conditions. It has followed aphthous fever (Eletti), and arisen under
a forcing ration, in hot weather (Callot, Cruzel), or under overwork
(Cruzel).
Causes in Dogs. Most cases result from infection by way of the
stomach and intestines, or by the transfer to the liver of the
ptomaines and toxins of such infections. It is thus related in its origin
to catarrhal jaundice and hyperæmia.
Lesions. In the earliest stage with albuminoid exudation into its
substance the liver may be greatly enlarged, its sharp edges rounded,
and its consistency softened. After a week’s illness atrophy may have
set in and the organ appears shrunken and of ocherous yellow. In the
early stages there may be sanguineous engorgement, the cut surface
may bleed freely, and small extravasations may show throughout the
liver substance, later the clay yellow hue, the granular aspect and the
absence of blood on the cut surface are characteristic. The margins of
the adjacent acini are indefinite or lost, and under the microscope
the hepatic cells are charged with granules (albuminoid, fatty and
pigmentary), while the nuclei are no longer demonstrable.
In cattle the liver may be double the normal size and at first of a
deep purple red, which may change later to the earthy yellow.
In dogs the liver is tumid and yellow, and marked by small pea-
like centres of softening. There is marked softening and the
microscope reveals the characteristic degeneration of the hepatic
cells.
Symptoms in the Horse. These resemble those of congestion
rendered more intense and therefore somewhat less obscure. The
attack is usually sudden, there may be rigor followed by
hyperthermia, dullness, pendent head, drooping eyelids, injected
conjunctiva with a yellowish tinge, unsteady gait and slight
indications of colic. There is anorexia, partial suppression of urine,
and what is passed is thick, glairy and brownish red, fæces are passed
with pain, and groaning, probably from compression of the liver, the
heart beats violently, while the pulse is small, breathing accelerated
and perspiration abundant. The temperature rises (101° to 106°) and
remains high throughout unless lowered through biliary intoxication.
Percussion over the liver and especially on the right side shows
increased area of dullness and marked tenderness. On the second or
third day the icterus usually increases, and a slight fœtid diarrhœa
may set in with marked fœtor of the pale or colorless discharges. The
jaundice is not, however, a criterion of the danger, as it may become
less marked or entirely disappear because of the extensive
degeneration of the hepatic cells and the arrest of the formation of
bile.
Diagnosis in the horse. The disease is recognized by the
coincidence of fever, with great depression, icterus, painful
defecation, constipation followed by a fœtid diarrhœa with lack of
color in the stools and by increased area of dullness and tenderness
in the region of the liver and especially on the right side. From
influenza which it resembles in many respects, it is distinguished by
the absence of watery discharge from the eyes, and by the entire
absence of all indication of contagion. The cases occur one at a time.
Prognosis in the horse. The disease is exceedingly fatal. When the
kidneys remain active, the poisons are eliminated and there may be
hope of recovery, but when urine is suppressed an early death by
poisoning is to be expected.
Treatment in the horse. A most important indication is to secure
depletion from the portal system. Calomel 1 dr., aloes 4 drs.,
ipecacuan 1 dr. may be given in bolus, and followed by small daily
doses of sulphate and nitrate of soda with bitters, with or without the
ipecacuan. Action on the kidneys is essential to secure elimination of
the poisons which threaten a fatal poisoning if retained. To favor the
same action fomentations may be applied to the loins. The frequent
presence of pathogenic microörganisms either in the bowels or liver
suggests the use of germicides (salol, salicylic acid, salicylate of soda,
naphthalin, naphthol, beta-naphthol, etc.) as in catarrhal jaundice.
Sinapisms or blisters applied to the right side of the chest and over
the short ribs may be useful, and after the subsidence of the more
violent symptoms, dilute mineral acids and especially nitro-muriatic
acid may be resorted to in combination with diuretics and bitters.
When appetite returns succulent, laxative, non-stimulating food in
small quantity should be given. Wheat bran mashes, carrots, turnips,
potatoes, apples, fresh grass, ensilage may be adduced as examples.
Throughout the disease the ingestion of an abundance of pure water
should be encouraged.
Symptoms in the ox. These may appear more tardily than in the
horse, loss of appetite, staring coat, dullness, pendent head and ears,
unsteady movements, rigors, drivelling of saliva from the mouth and
grinding the teeth are usually noted. To these are added the more
diagnostic symptoms of slight (or severe) jaundice, constipation
followed by a fœtid light colored diarrhœa, a strong disposition to
remain recumbent, marked suffering attendant on rising, arching of
the back when up, and tenderness on percussion over the right
hypochondrium. The temperature gradually rises, though more
slowly than in the horse, and may again descend under a profound
poisoning.
Course. The disease reaches its acme in four to six days, and
generally has a fatal issue.
Treatment, is on the same lines as for the horse only as a
purgative, sulphate of soda may advantageously replace the aloes.
Symptoms in the dog. The symptoms are those of congestion in an
exaggerated form. There are muscular tremors, erection of the hair,
followed by rising temperature up to 105° or 106°, an icteric hue of
the mucosæ, the pulse is accelerated, strong, irregular, respiration
rapid, panting, fœtid breath, ventral decubitus, and prostration
extreme. Appetite is completely lost, the bowels become relaxed, the
stools fœtid, the right hypochondrium painful on pressure or
percussion, and the urine greatly reduced and icteric or suppressed.
This feature of urinary suppression, determines a rapid poisoning
and death in two or three days.
Treatment must follow the same lines as in other animals, a
purgative of calomel and jalap, followed by diuretics, laxatives,
derivatives, and above all germicides. In case of survival mineral
acids, aqua regia, bitters, and a carefully regulated diet will be in
order.
SUPPURATIVE HEPATITIS. HEPATIC
ABSCESS.
Causes in horse: pyæmia, omphalitis, thrombosis, infection, biliary calculi,
concretions or parasites, foreign bodies, hot, damp climates, strangles,
brustseuche, glanders, endocarditis. Lesions in horse: from parasites and
mechanical irritants, pea-like or hazelnut; embolic abscess, pin head to hen’s egg;
infection from strangles, foreign bodies, etc., may be of large size, and burst into
adjacent organs, the peritoneum or externally. Symptoms in horse: of pre-existent
malady, remitting fever, successive chills, intermittent icterus, hypochondriac
tenderness. Spontaneous recovery, aspiration, opening, antiseptics locally and
generally. Lesions in ruminants; secondary multiple abscesses, bean-like or (with
foreign body) very large, may extend into adjacent parts. Symptoms in cattle: fever,
chills, jaundice, tympany, diarrhœa, dysentery, wasting, tender right
hypochondrium. Treatment: as in horse. Causes in dog: foreign bodies, tumors,
infections, blows, traumas. Lesions: traumatic abscesses, single, large, infectious
abscesses multiple, small. Former fœtid. Symptoms in dog: hepatic congestion or
colic, then chills, prostration, irritability, tenderness of right hypochondrium,
nausea, vomiting. Treatment in dog: antiseptic aspiration, laparotomy.
Causes in the Horse. Hepatic abscess arises from a great many
primary morbid conditions. As a secondary abscess it is seen in the
different forms of pyæmia and especially in suppurative omphalitis
in young animals. It may start in thrombosis determined by clots or
septic matters carried from a distance through the portal vein or
hepatic artery, in biliary calculi or concretions, in parasites
introduced from the duodenum, in barbs or husks of the cereals that
have penetrated through the biliary ducts, or in bacteria or their
toxins which have been carried from the bowels, spleen or pancreas.
The government veterinarians have found it a comparatively
common lesion in the hot damp climate of Hindoostan, and a similar
frequency has been noticed in west Africa. Among general affections
it is liable to occur in strangles, contagious pneumonia, glanders,
endocarditis of the left heart and phlebitis with the formation of
thrombi in the lungs. In the two last named disorders, the affection
takes place by the simple transference of detached clots to the liver to
block its arteries or capillaries. Or it may be that micro-organisms
are transferred in the same way. With modern views of suppuration
the presence of the pyogenic organisms must be conceded.
Lesions in the horse. Cadeac distinguishes the different types of
hepatic abscess as: 1st biliary abscess in which suppuration
commences in the interior of the biliary ducts and usually from
parasites or mechanical irritants introduced or from calculi or
concretions formed within them: these rare abscesses contain biliary
salts, pigments, and epithelium and acquire the size of a pea or
hazelnut: 2d Metastatic abscesses which start in the arterial, portal,
or capillary vessels, by the arrest of infecting clots, which determine
a further clotting, the obstruction of the vessel, the accumulation of
leucocytes and the formation of abscess of the size of a pin head or
larger up to a hen’s egg, surrounded by a hæmorrhagic infarct
softening in the centre: these are numerously disseminated through
the liver: 3d Mechanical Abscess due to the penetration of foreign
bodies or parasites: 4th Infection as in strangles. These may attain a
large size, cause adhesion to adjacent organs, and rupture into the
chest, the colon, stomach or peritoneum. The pus may even escape
externally through the right hypochondrium.
Symptoms in the horse. These are always obscure and vary much
with the source of the malady. If there has been a pre-existing
hepatic malady the symptoms of that will be in evidence; if an
omphalitis its existence may still be recognizable; if pulmonary or
cardiac disease, that may be detected; if parasites, evidence of their
existence may perchance be found; if gall stone, a previous violent
hepatic colic with icterus may have occurred; and if intestinal septic
disorder, there may be the testimony of intestinal troubles. The more
diagnostic symptoms are a fever of a remittent type, one or several
violent shivering fits, a marked jaundice which like the fever shows
exacerbations, and a similar irregularity of the condition of the urine
which may be successively of a dark brown, a deep yellow, and a
transparent amber color. Tenderness and grunting on percussion of
the right hypochondrium would be an additional aid in diagnosis.
Treatment. Death has been hitherto considered as the inevitable
result, yet recoveries may ensue after rupture into the colon or
through the abdominal walls. If the seat of the abscess can be
ascertained its evacuation through an aspirator and the subsequent
injection of an antiseptic would be appropriate. The concurrent use
of antisuppurants like hyposulphite of soda, or sulphide of calcium
would also be in order.
Causes in Cattle. Hepatic abscess is much more frequent in cattle,
and is commonly a result of perforation by sharp pointed bodies
(needles, pins, nails, wires, etc.) from the reticulum and rumen, or of
parasites, or biliary calculi. Other cases are occasioned by the
presence of tubercles, actinomycosis, or omphalitis.
Lesions in Cattle and Sheep. Secondary abscesses are usually
multiple and disseminated through the organ, though Cadeac says
they are more common in the left half. They vary in size from a bean
to a pigeon’s egg, project often from the surface, and contain a viscid,
creamy, yellowish or greenish pus. Abscesses dependent on foreign
bodies often attain a great size, so as to contain a pint or quart of pus
(Landel). They may make their way through the diaphragm, rumen,
or abdominal wall leaving a thick cicatrix in the liver, or they may
become slowly absorbed and dry up into a putty-like or cretaceous
mass. Brusaferro found hepatic abscesses in lambs twenty to thirty
days old—probably of omphalic origin.
Symptoms in Cattle are usually very obscure. Fever, shivering fits,
jaundice, indigestion, diarrhœa or dysentery, emaciation, colics,
tender right hypochondrium, and peritonitis may all be in evidence
but the diagnosis is little better than a guess.
Treatment when possible at all would be on the same lines as for
the horse.
Causes in the dog. According to Cadeac these are mostly foreign
bodies (needles, pins, etc.) which have been swallowed, tumors of the
liver or adjacent organs, phlebitis and thrombosis of the portal vein,
pyæmia, septicæmia, and external injuries (kicks, blows, contusions,
falls, etc.)
Lesions in the dog. As in the other animals traumatic abscess is
usually solitary and large, secondary abscess multiple and small. The
pus developed around a foreign body is reddish, greenish and fœtid,
that of the metastatic abscess is usually whitish or yellowish and with
a sweet odor.
Symptoms in the dog are those of hepatic congestion, or violent
gall stone colic, followed by severe rigor, great depression, or
irritability, and tenderness over the right hypochondrium. Nausea
and vomiting is a marked symptom though not a diagnostic one.
Treatment. If the flaccid abdominal walls will allow of the locating
of the abscess it should be treated by aspiration and antiseptic
injections. It would even be admissible to perform laparotomy, stitch
the wall of the abscess to the external wound, and empty it under due
antiseptic precautions.
INFECTED HEPATITIS. NODULAR
NECROBIOSIS OF THE LIVER.
In ox, sheep, pig, dog, horse. Necrotic areas projecting on surface of liver.
Causes: bacteria, toxins, from bowels, womb, navel. Lesions: In cattle dirty gray
nodules in brownish red liver, nodules firm, granular, necrotic, elements do not
stain, later leucocytes and fibro-plastic growth in periphery. In lambs the nodules
are white, common to the lungs and pleura, pathogenic to rabbit. In pigs nutmeg
liver, cells without nuclei, fatty, granular, pathogenic to rabbits, guinea pigs, rats
and young pigs. In dog, nutmeg liver, with violet areas, and white spots, 1–2 lines,
having granular, fatty cells without nuclei. Symptoms: fever, constant lying, tarry
fæces, icterus, tender right hypochondrium, and those of the primary disease.
Treatment: antisepsis of primary seat, and bowels, elimination by kidneys, general
antisepsis, stimulants, etc. Case usually hopeless. Prevention.
This has been observed particularly in cattle, but also in sheep, pig,
dog and horse. It is characterized by the formation of circumscribed
areas of gangrene, becoming hard, dry, yellowish and usually slightly
projecting beyond the adjacent surface. Its infected character is
shown by the presence in the lesion and adjacent parts of the hepatic
tissue of an abundance of bacteria, which, from the varied
description, appear to differ in different cases. The cause may
however be safely stated as one of the bacteria of gangrene. It is
alleged with some show of reason, that the lesion may be determined
by the action of toxins and ptomaines produced by bacteria in the
alimentary canal and carried to the liver with the portal blood
(Cadeac). The bacteria themselves commonly come from the same
source, (Stubbe), but also from the uterus (Berndt), the mammæ
(LeBlanc), and above all from the suppurating or septic umbilicus.
McFadyean in five cases found a long slender bacillus, Hamilton in a
single case in the horse found cocci, Rivolta in an infectious hepatitis
in sheep found bacterium subtilis agnorum, and Semmer found the
same condition in young pigs from micrococci introduced through
the diseased umbilicus.
Lesions. In cattle the liver has a general brownish red, or greenish
white color, and shows projecting, hard nodules of a dirty gray color
more or less tinged with yellowish brown. The margins of these hard
nodules are very sharply defined, and on section show a
homogeneous granular surface, devoid of areas of softening or of
connective tissue, and formed of the hepatic parenchyma in a state of
necrobiosis. The granules and nuclear elements do not stain like
those of healthy liver. As the disease advances the periphery of the
nodule may be invaded by leucocytes and become the seat of a fibro-
plastic hypertrophy (McFadyean) with the ultimate formation of
cicatricial tissue (Stubbe).
In lambs Rivolta found the necrosed nodules standing out as white
patches under the capsule of the liver, but similar lesions were met
with in the lungs and pleuræ, an observation which has been
confirmed by Hanbold. The affection was conveyed by inoculation to
the rabbit.
In pigs Semmer found nutmeg liver, deep red or grayish yellow,
hypertrophied, the hepatic cells swollen and divested of nuclei but
containing fatty and pigmentary granules. It was inoculable on
rabbits, guinea pigs, white rats and on young pigs.
In the dog, Courmont and Doyon found congested liver (portal
congestion) with projecting patches of a deep violet color and sharply
defined borders, and one to two lines in diameter, also salient white
spots with distinct outlines. In the white spots the hepatic cells had
lost their nuclei and were charged with fatty granules.
Symptoms. These are indications of hepatic disease. In parturient
cows, Berndt noted fever (102° to 104°), anorexia, stiffness, cough,
labored breathing, intense thirst, constant decubitus, and
constipation followed by lowering temperature, tarry fæces and
icterus. The region of the liver was very sensitive to pressure or
percussion. In the other animals the symptoms appear to be largely
over-shadowed by those of the primary disease, but the same general
indications of jaundice, hepatic tenderness and digestive disorder are
superadded.
Treatment when it can be intelligently adopted, consists largely in
evacuation and antisepsis of the seat of primary infection, and of the
prima viœ, and in maintaining elimination by the kidneys. In this
way, as in congestion and hepatitis, the concentration of the poison
is as far as possible counteracted, and an opportunity may
sometimes be furnished for the recuperation of the liver cells. As a
rule, however, the case is hopeless, and thus preventive measures, by
cleanliness, disinfection and antisepsis of the ascertained sources of
the infection are indicated.
PERIHEPATITIS.
Inflammation of capsule of liver (external and Glisson’s). Causes: Traumas,
infective diseases, phlebitis of the portal vein, chill, distomatosis. Lesions:
Peritonitis and inflammation of the capsule in patches, yellowish gray exudate,
fibroid thickening or pus. Adhesions to adjacent objects. Thickening of trabeculæ.
Symptoms, tardy respiration and circulation, tender hypochondrium, colics,
diarrhœa, painful defecation, moan with expiration. Slight cases recover. Sequelæ:
compression of portal vein or bile duct, gastric catarrh, piles, etc. Treatment:
Salines, alkaline diuretics, mineral tonics, bitters.
This is inflammation of the external capsule of the liver and
Glisson’s capsule. It may arise from direct mechanical injury, or by
extension of inflammation from adjacent structures, such as the
peritoneum. It may also complicate contagious pneumonia in the
horse, tuberculosis in the ox, pneumoenteritis in pigs, and also
phlebitis of the vena portæ (Cadeac, Morot). It may follow a chill, or
distomatosis.
Lesions. These are essentially peritonitis circumscribed by the
liver, and extending to the proper capsule, and its vaginal
investments of the hepatic vessels. It is usually limited to certain
spots which become the seats of a yellowish gray exudation, with a
tendency to fibroid development and thickening, but sometimes
degenerating into pus. The deposits on the outer side of the hepatic
peritoneum may develop false membranes and fibrous adhesions to
surrounding objects, the diaphragm, omentum, stomach or intestine.
The deposits under the peritoneum lead to similar fibrous
development with hypertrophy or thickening of the capsule, the
trabeculæ extending thence into the liver and the vaginal sheaths of
the vessels. Such areas of thickening are revealed as depressed spots
or patches of a white color, and showing a firm fibrous, pearly
appearance when incised. Such lesions are not uncommon in the
livers of horses, cattle and swine. In the pig they may have a violet, or
brownish red color, but with spots of other colors—grayish or
brownish (Kitt).
Symptoms. Dopheïde, who has studied the disease in cows and to
a less extent in horses, found a reduction in pulsations (26 per