Ricafort, Maxine S.

GRP- 2H

DRUG NAME MECHANISM OF ACTION INDICATION/ ADVERSE EFFECT NURSING

CONTRAINDICATION RESPONSIBILITIES

GENERIC: Spironolactone acts on the INDICATION: CNS: dizziness, BEFORE:

distal renal tubules as a clumsiness, headache
Spironolactone competitive antagonist of Adjunctive therapy in • Monitor vital signs
aldosterone. It increases edema associated with CV: arrhythmias
BRAND: the excretion of sodium CHF, nephrotic syndrome, • Assess for hyperkalemia;
chloride and water while hepatic cirrhosis when GU: erectile dysfunction renal disease; pregnancy,
Aldactone conserving potassium and other therapies are lactation.
hydrogen ions. inadequate or ENDO: breast
CLASSIFICATION: inappropriate tenderness, • Avoid foods that are rich in
gynecomastia, irregular
potassium.
Potassium - sparing CONTRAINDICATION: menses, voice
diuretics / Aldosterone deepening
Antagonist Hypersensitivity to the
DURING:
drug, Anuria, F and E: hyperkalemia,
DOSAGE: hyperkalemia, acute or hyponatremia • Give daily doses early so
progressive renal that increased urination
25mg insufficiency. Hemat: agranulocytosis does not interfere with
sleep.
ROUTE:
• Administer drug not
ORAL exceeding 3 tablets in 15
minutes.
FREQUENCY:
• Take the drug early
OD because of increased
urination.
AFTER:

• Check for any allergy.

• Arrange for regular

evaluation of serum
electrolytes and BUN.

• Report any swelling in

your ankles or fingers,
dizziness, trembling,
numbness, fatigue