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Emergency Psychiatry Primer On Series 1St Edition Tony Thrasher Editor Full Chapter
Emergency Psychiatry Primer On Series 1St Edition Tony Thrasher Editor Full Chapter
Acknowledgments vii
Contributors ix
SE C T IO N I . T H E A P P R OAC H T O E M E R G E N C Y
P SYC H IAT R IC EVA LUAT IO N
SE C T IO N I I . SP E C I F IC D I S O R D E R S , D IAG N O SE S ,
A N D SYM P T OM S F R E Q U E N T LY E N C OU N T E R E D A S
P SYC H IAT R IC E M E R G E N C I E S
SE C T IO N I I I . SP E C I F IC P O P U L AT IO N S F R E Q U E N T LY
E N C O U N T E R E D A S P SYC H IAT R IC E M E R G E N C I E S
15. Children and Adolescents 295
Heidi Burns, Bernard Biermann, and Nasuh Malas
16. Geriatrics 321
Daniel Cho, Junji Takeshita, Victor Huynh, Ishmael Gomes, and
Earl Hishinuma
17. Developmental Disabilities 344
Justin Kuehl
18. Perinatal Patients and Related Illnesses, Symptoms, and
Complications Related to Pregnancy 362
Sarah Slocum
19. Victims of Physical and Sexual Violence 376
Kristie Ladegard and Jessica Tse
SE C T IO N I V. D I SP O SI T IO N , A F T E R C A R E ,
L E G A L I S SU E S , A N D F U T U R E D I R E C T IO N S
20. Tool, Constraint, Liability, Context: Law and Emergency Psychiatry 401
John S. Rozel and Layla Soliman
21. Documenting Risk Assessments and High-Acuity Discharge
Presentations 420
Shafi Lodhi
22. Trauma-Informed Care, Psychological First Aid, and
Recovery-Oriented Approaches in the Emergency Room 440
Benjamin Merotto and Scott A. Simpson
23. Collaborations Within the Emergency Department 451
Julie Ruth Owen
24. Collaborations Beyond the Emergency Department 463
Margaret E. Balfour and Matthew L. Goldman
25. Quality Improvement in Psychiatric Emergency Settings:
Making Care Safer and Better 479
Margaret E. Balfour and Richard Rhoads
Index 493
Acknowledgments
My significant gratitude toward the finest group of physicians I have ever worked with—
the Psychiatric Crisis Service of Milwaukee County. Love and appreciation to Amy,
Noah, and Owen for their patience, support, and enthusiasm for not only our mission
but also my passion.
Junji Takeshita, MD
Professor and Associate Chair, Clinical
Services
Geriatric Psychiatry Program Director
Department of Psychiatry
John A. Burns School of Medicine
University of Hawai‘i at Mānoa
Honolulu, HI, USA
SECTION I
THE A PPROAC H TO E M E RG E NC Y
P SYC HIAT R IC EVA LUAT ION
1
An Initial Approach to the
Emergency Evaluation
Pitfalls, Pearls, and Notice of Countertransference
Janet Richmond
Introduction
This chapter introduces the new clinician to techniques used to engage and evaluate
the psychiatric patient in the emergency setting. The goal of the examination is to
quickly establish rapport, contain affect, and gather enough information to arrive at a
differential diagnosis that informs stabilization and disposition. An effective interview
should be trauma-informed, collaborative, noncoercive, and have a treatment compo-
nent.1–5 The evaluation is rapid and focused rather than a complete workup as is done
in an outpatient intake. In the emergency psychiatric evaluation, attention is paid to
the chief complaint, the history of the present illness, the mental status examination,
a safety assessment, and the patient’s request.3,6–8 A biopsychosocial understanding
of the patient’s situation is also necessary to inform treatment and disposition. The
objective is to elicit as much information as needed, focusing more on how to elicit
the information rather than asking a list of actuarial questions that frequently give
only limited information. The exam is a process of generating hypotheses that change
over the course of the interview as new information is elicited. For example, is the pa-
tient psychotic because he stopped his antipsychotic medication? The patient appears
psychotic; is he truly psychotic or just terribly anxious? Or is he in the middle of a
thyroid storm? Although this type of interviewing may appear to be inefficient, it is a
systematic way of interviewing that elicits information organically yet is not lengthy
to conduct. Finally, this model of interviewing draws on psychoanalytic1,9 and object
relations theory.
In the first few minutes of the interview, the clinician generates hypotheses, which
the clinician rules in or out. Then, based on further information, the clinician generates
more hypotheses. More serious conditions, such as acute medical illness, psychosis, or
homicidal or suicidal ideation/intent, are first on the list of hypotheses to rule in or out.
As noted above, performing an emergency psychiatric examination can be done
without a preset list of questions and can elicit more information than a reductionistic
checklist. Interviewing techniques include the use of open-ended questions interwoven
with more focused, closed-ended questions; sitting in silence; and paying attention to
one’s own countertransference feelings, both physiologic and emotional.3,12
Most patients are not seeking a diagnosis in the emergency department (ED), but cli-
nicians strive to make one and then believe that the assessment is complete. Lazare and
Engel argue that there are more elements to take into consideration. In my clinical work,
this type of formulation has been useful even in the evaluation of potentially suicidal
patients. It has often obviated the need for hospitalization, even when multiple risk fac-
tors superficially indicated that the patient was imminently lethal and in need of invol-
untary hospitalization. The following case illustrates a biopsychosocial evaluation.
Case Example
A 40-year-old male with no known prior psychiatric or medical history is brought to the
ED after becoming agitated at work. He is dressed in a suit and tie and is neat and clean
except for excessive sweating and a haphazardly undone tie. He reports feeling agitated
and believes he is having “flashbacks” to the terrorist attacks on September 11, 2001 (9/
11), when he was in one of the towers of the World Trade Center in New York City but
escaped unharmed. At the time, he had nightmares and exaggerated startle responses,
but these remitted within the first month after the event. His primary care doctor had
An Initial Approach to the Emergency Evaluation 5
diagnosed insomnia and had prescribed a sleeping aid (zolpidem), which the patient
used for only 2 weeks. He does not drink, use drugs, or take supplements. He is an at-
torney, and he is embarrassed that he was so upset in front of his partners, one of whom
took him to the ED. His wife corroborates the history. From a biomedical framework,
the change in mental status could stem from an array of new-onset medical illnesses,
including an acute cardiac event, thyroid storm, hyperglycemia, or impairment of the
hypothalamic–pituitary–adrenal axis. A full medical workup is completely negative. The
medical diagnosis is panic attack. The next step is to generate hypotheses, the first being
whether the diagnosis of panic attack is accurate or due to another psychiatric illness or
an occult medical illness that the medical examination did not pick up.
Is there a family history of psychiatric illness such as bipolar disorder that could now
be emerging in the patient? Is this a delayed post-traumatic stress disorder reaction and,
if so, what precipitated it? Is the patient’s report that he does not use substances accurate?
As he speaks, the clinician listens for clues as to what may have precipitated these
“flashbacks” (which are actually intrusive memories of the event and not actual flashback
phenomena). From the social component, are the patient’s marriage and job secure? Is he
worried about finances? From the psychological frame, what might be triggering these
intense memories? What happened to disrupt his usual coping skills?
During the interview, the clinician listens for data to confirm or refute hypotheses,
asking focused questions when necessary and generating further hypotheses, exploring
each thoroughly. The patient’s marriage, job, and finances are secure. There are no recent
life cycle events and no family psychiatric or substance abuse history. Once again, the
patient denies personal use of substances and is convincing. He reviews his reactions to
9/11 and, when asked, goes into some detail about the specific traumatic event that he is
reexperiencing today. The clinician then asks the patient to “walk me through your day”
(up to and including the onset of today’s symptoms) to determine a precipitant. Almost
immediately the patient pauses, is shocked, and “remembers” that while on his way to
work that morning, he was delayed by a serious traffic accident in which a car caught
on fire and a father and two young children were rescued unharmed. At the time of 9/
11, the patient’s two children were school aged, and as he watched the towers blazing,
he remembered seeing two children approximately the same age as his children being
hurried by their mother to safety. Throughout the day (of 9/11), he had had intrusive
thoughts that his children could have been in the rubble, but his wife had kept them back
home due to a stomach flu. While retelling his story, the patient had an upsurge in adren-
ergic symptoms that resolved as he was able to understand his reaction. Despite gener-
ating all these hypotheses and doing so in a nonstructured format, the entire evaluation
took 20 minutes. An additional 10 minutes was spent helping the patent reintegrate his
experiences and reequilibrate.
The Interview
The best interview does not feel like an interview to the patient, nor does it look like
one to the casual observer. Instead, it looks like a conversation dedicated to learning
about the patient, their illness, their ability to cope, and what the patient would like to see
happen in the ED. This method of interviewing builds rapport.
It is current practice to use a trauma-informed approach for all patients. The emer-
gency room environment may be threatening or trigger memories or reactions from past
6 Emergency Psychiatry
traumatic events. These may have occurred in a previous emergency room visit or with
previous medical providers. Listen and observe for any signs that the patient may be
tentative, agitated, or even hostile. Chapter 22 discusses trauma-informed care in detail.
The Environment
Attention to the physical environment as well as the clinician’s initial nonverbal behavior
sets the tone. General principles for safety in the environment include the removal of
large and small items such as pens and paper clips that can be thrown. When indicated,
have Security readily available. Friendly but not intense eye contact is preferred. Keep
your hands visible. Both patient and clinician should have equal access to the door, and
if the patient appears volatile or unpredictable, stand or sit far enough away so that you
are not punched or kicked.3 In all interviews, try to sit at or below the patient’s eye level.
If possible, avoid standing over the patient; it makes for a symbolic imbalance of power.
Observation
Even before entering the room, there is a wealth of information to be gleaned from
simply observing the patient, first in the waiting room and then in the exam room. What
the patient is wearing, their level of neatness and hygiene, as well as their psychomotor
activity can be diagnostic tools and generate hypotheses. The well-dressed and groomed
patient in Vignette 1.1 was diaphoretic with his collar and tie loosened. These two factors
should lead a clinician to generate questions about any acute medical illnesses or the
patient’s level of orientation and cognitive functioning.
Verbal Engagement
Introduce yourself, ask the patient’s name and how they would like to be addressed.
Consider addressing the patient by their last name because using their first name might
appear overly personal or infantilizing, creating an imbalance of power. Other patients
prefer to be called by their first name, despite the risk of overfamiliarity.
Patients come to the ED with many underlying wishes and longings. These “requests”8
are different from the chief complaint and are frequently not verbalized. They can some-
times be communicated through body language or affective tone. For example, a patient
whose chief complaint is “I’m suicidal” might have the underlying wish that the clini-
cian uses their authority to muster up a change in the patient’s situation. The request is
“I wouldn’t be suicidal if my girlfriend came back to me. Could you call her and talk to
her?” (really, “persuade her to change her mind since she’ll listen to you because you’re
the doctor”). The request may or may not be realistic or possible, but it is still important
to uncover. Otherwise, the interview may reach an impasse or at the end of the exam the
patient may be dissatisfied with the outcome and either leave in a huff or delay the end of
the visit. Asking “What would you like to see happen here today?” early in the interview
allows the clinician to address these requests. If the patient replies “I don’t know,” the
clinician can respond that “often people have an idea of what they want accomplished in
the visit. I’d like to hear what it is [even if it’s not easy to talk about]” or “As we continue to
talk, let’s both try to figure out what it is.”
glosses over the content too quickly or shows no affect, slow them down and develop a
timeline: “First you came home, and then your daughter walked into the kitchen, etc.”
Watch for emerging affect, the patient’s thought process and cognition. If the patient
floods with affect and cannot contain themself, slow the patient down and ask about
content and objective facts. If too much content is without affect, ask about the patient’s
feelings. Sometimes it is helpful to verbalize them for the patient: “If that happened to
me, I’d be terribly upset.”
Once the alliance is established, the clinician can then explore more deeply and use fo-
cused, specific questions. If you wonder whether the patient is psychotic, asking focused
questions such as “Do you ever have the feeling that others are following you?” is a risk if
the alliance is not adequately established. A less challenging entry to the question might
be, “Do you tend to be a cautious person?” Focused questions are essential, but timing is
crucial. Moving in with that type of question too soon can challenge, offend, or frighten
the patient. If that happens, apologize, reestablish rapport, and resume building the alli-
ance. Rehabilitate the interview and then later return to that question.2
Other elements of the psychiatric examination, such as past psychiatric, medical, family,
military, and social history, may be useful to understand the current presentation. Again,
collecting this information for completion sake is not the goal of the emergency evalua-
tion. Whatever extraneous information you gather is “free information.”3
Other interviewing techniques include summarization, clarification, interpretation,
and confrontation. The latter are to be used judiciously but can be very effective. An
example of an interpretation might be, “You mentioned that your mother died from
stomach cancer, and you’re here today with a stomachache. Do you see a connection?”
Another example is, “Your boss said something so hurtful and humiliating that you
wanted to disappear, so you thought about killing yourself.” (This interpretation actually
helped a patient reconstitute. She was no longer suicidal, realized how outrageous the
boss had been, became appropriately angry, and was successfully followed in outpatient
care.) The following is an example of an interpretation and a confrontation: “You had a
disagreement with your boss, and now you’re here having an argument with me when
your beef is really with the boss. You’re trying to get under my skin the way he [your
boss] got under yours.”
Mental Status
Aside from the patient’s request, history of present illness, and collateral information, the
most essential piece of the emergency exam is the mental status examination, which can
also be done through careful listening, followed by a focus on areas needing clarification
or exploration. For example, elements that could potentially be gathered without ask-
ing specific questions are level of arousal, motor, speech, cognition, orientation, attitude,
thought process, affect, and overall mood. A nonfocused interview might even reveal the
presence or absence of hallucinations, delusions, and suicidal or homicidal ideation. If
not, these areas can be quickly explored.
An Initial Approach to the Emergency Evaluation 9
Case Example
A 78-year-old previously healthy and active female is brought to the ED by her son,
who reports an insidious decline in functioning for the past 2 months. Her husband of
52 years died from a long-term illness 8 months ago. The couple had been very devoted to
each other, and the patient had cared for her husband at home. She had help, but she felt
strength and purpose helping him through his last days. Following his death, the patient
seemed to go through the grieving process uneventfully and after 3 months had resumed
her usual activities—visiting with friends, going to the theater, and playing tennis twice a
week. Although episodes of sadness and longing surfaced occasionally, they were short-
lived and occurred on anniversary dates. Most of the patient’s memories of her husband
brought comfort and a smile. The hypotheses generated were whether there was some
occult difficulty grieving the loss of her husband (psychological) or a problematic social
impact (change in status to a widow, financial problems, etc.).
Approximately 2 months ago, the patient had stopped playing tennis and reported
feeling too tired to join her friends for evening theater. She began sleeping more and
had gained approximately 10 pounds, which she attributed to “sitting around all day.”
Usually a meticulous and stylish dresser, she began wearing old sweatshirts with
stains. “I’m not going anywhere, so why should I dress up?” Her appetite was poor,
and she complained about decreased concentration. Based on what he had read about
early signs of cognitive impairment, the son was concerned that the patient was expe-
riencing the beginning of dementia. The patient was anhedonic and anergic but was
not suicidal.
The interview went as follows:
Clinician: Hello Ms. Boston, I’m Sarah Brown from the Psychiatry Department. What
brings you in today?
Patient: I’ve been feeling down lately. My son thought I should come in.
Clinician: You’ve been feeling down, could you say more?
Patient: Not really; just don’t feel like doing anything. I just sit around the house all day.
Clinician: And what do you do in the house?
Patient: Just sit, watch television.
Clinician: I understand that’s very different from how you normally are. Is that right?
The patient goes on with sparse speech, but she is cooperative with the interviewer. She
describes most of her neurovegetative symptoms by saying more about her day: Does she
cook? No, no appetite. How’s her sleep? Can’t fall asleep. The interviewer asks more fo-
cused questions to fill in the information:
Clinician: When you’re watching television, can you keep track of the story or do you
drift off?” (The clinician is asking about concentration.) Are there any shows that are
your favorites?” (If the patient perks up and lists her favorite show, she is not perva-
sively anhedonic, which might rule out depression.)
10 Emergency Psychiatry
Clinician: Your husband died 8 months ago. I’m so sorry. How has the adjustment been
going?”
Again, the interviewer gleans what she can from the patient while still attending to the
patient’s motor activity, eye contact, production of thoughts, and affect. She listens for
any psychotic material and for any memory issues as the patient tells her story in her
own words.
If the patient has not mentioned particular areas that the interviewer deems relevant,
the interviewer can then ask focused questions: “Did you ever think about joining him
[in death]?” This question comes later in the interview so that rapport has been achieved
and sustained, and the question is in context. It could have been asked in the section on
neurovegetative signs (“Is the depression ever so bad that you think about killing your-
self?”), but knowing that many bereaved persons consider joining their loved ones, the
interviewer waited until this area was explored. The clinician can ask directly about any
social fallout from the husband’s death—financial problems or concerns about selling
her house. Are couples’ friends pulling away now that she is single? The psychosocial
aspects of this patient’s presentation have been carefully explored, as well as the biolog-
ical component of a clinical depression. Thus far, the patient appears to have a clinical
depression. The bereavement has been unremarkable without evidence of avoidance or
impaired functioning, and there are no financial or other social issues that concern the
patient. She has ample funds, is comfortable in her current home, and has maintained
her friendships.
The interviewer also considers other potential medical possibilities, not yet accept-
ing the conclusion that this patient has a clinical depression. She has noticed that
the patient’s skin is dry and flaky, and her face is plethoric. The patient has little psy-
chomotor movement, except for an occasional rubbing of her arms because she is
cold. Her unwashed hair is also sparse. Is there an underlying medical condition that
has not been picked up in the medical clearance? The interviewer thus asks about
her medical history and family medical history. The patient has no active medical
problems other than well-controlled hypertension for which she has taken the same
antihypertensive for years. Her son interrupts and says that the patient also has hy-
pothyroidism, but there is no mention of this medication on the triage note. The son
states that this is an example of the patient’s forgetfulness. The patient suddenly looks
up and says,
Oh, I forgot to refill my thyroid prescription! I noticed that I was running low and had
a reminder to call my doctor, but that was the day the patio deck collapsed. I was so fo-
cused on that, that I never called the doctor for the refill. I’ve been off my thyroid med-
ication for the past 3 months. Could that be the problem?
For the overtalkative patient, displaying circumstantial or tangential thinking, the in-
terviewer needs to focus more. For example, “Before you talk about Y, let’s go back to
X.” This tells the patient that you have been listening and want to help them organize
the information. This may have to be done several times until you either have the infor-
mation needed or determine that the patient cannot provide it. For example, “Let’s go
back to what you said about your experience with [X medication]. What were the side
effects?” If the patient goes off in another area, “It all started when I went to the doctor”
(who prescribed the medication, etc.), the interviewer can interrupt and say, “But I was
asking specifically about side effects? Did you have nausea?” Hypotheses can be gener-
ated about the reason for the circumstantial thinking: Is there some cognitive decline? Is
there a thought disorder? Is this an example of an obsessional style or distancing way of
relating? Is the patient purposely being vague?
If the patient rushes through the narrative—“I had a fight with my mother, and she
called the cops”—slow it down and get the time sequence. This helps both you and the
patient see the event more objectively and helps you determine if the patient can think in
temporal sequence. “Let’s go back; walk me through what happened. I want a picture in
my head as to what happened.”
The patient may be silent out of fear, suspicion, defiance, or deference to authority fig-
ures. If mute, consider dissociation or catatonia, which can suddenly burst into catatonic
excitement. You will need to quickly sense what the problem is by gaining clues from col-
lateral information and nursing staff who have already seen the patient.
Comment on their silence and ask, “What is going on?” You can think out loud and
suggest that “silence has many meanings—fear . . . anger . . . defiance . . . shock . . . or ex-
haustion. Do any of them fit your situation?” If the patient continues to be silent, ask if
they would like juice or food. Asking about sleep, or whether they are cold or too warm,
can break the ice. Would they like some medication? These are nonthreatening questions
that good mothers and good doctors ask. If the patient continues to be silent, excuse
yourself and tell the patient when you will return. You may need to return several times,
but something will declare itself at some point.
For the suspicious or fearful patient, tell them that you are there to help. Do not make
any quick motions and tell them exactly what you are doing, even if you are just sitting
down. “I’m going to sit here; you can have a seat over there. We’re both going to have
access to the door. . . . You look frightened; can you tell me if that’s the case?” If you do
not want to give the patient the impression that you can “read their mind,” you can share
your feelings: “I’m feeling uneasy/nervous/frightened in here?” If you are truly in fear,
appeal to the patient’s wish to be in control: “I’m feeling frightened; should I leave the
room? Should I be worried about my safety in here?” Even a suspicious patient might
well relax more if the interviewer shares the patient’s feelings. I have often seen a cu-
rious glance after I have said this to a patient. If the patient tells you to get out, do so. Do
12 Emergency Psychiatry
not try to exercise your authority now. The patient is telling you that they have tenuous
control, and this is a warning to you. Leave and get help. You can go back with help and
ask the patient if there is something you can do to help them feel calmer. “Perhaps some
medication? What has worked for you in the past?” This tells the patient that you are not
going to use your authority to control them but to collaborate with them and value their
recommendations. If the patient reassures you that you are safe, you need to determine
if you believe it. If not, you may state, “I still don’t feel comfortable. I’m going to leave the
room right now” (and get out of the room quickly, but do not turn your back because
the patient might attack from behind). If you believe the patient, then you can gently
begin the interview, trying to build rapport and an alliance. “Can you tell me what you’re
feeling? Can you tell me what happened that you’re here?” or “My notes say that the po-
lice brought you in after your mother called 911; what happened?”
Paranoid patients may interpret empathic or sympathetic statements as pity. They fear
that their power will be diminished. They are frightened and offended by this level of
intimacy. They are not used to people being kind to them unless there is a price to pay.
Staying neutral yet kindly is the best strategy. A paranoid patient also has a strong gran-
diose streak: Why else would aliens choose him over others? You can speak to that with a
less challenging question, “Wow, that’s quite a burden to be chosen and to receive all this
negative attention.” You are allying with both the grandiosity and the undesired atten-
tion. “How did these people land on you [to be] the brunt of their anger?” It can diffuse
tension and help build the alliance.
If the patient has been talking about all the stress in their life, you can determine the
patient’s state of hopelessness by reflecting and asking, “You’ve been dealing with so
much, how do you keep going? What gives you hope?” Or ask, “What matters to you
most?”16 Here, you are assessing protective factors without having to resort to pat ques-
tions such as “Who’s your support?” That type of question can be off-putting: “Don’t
pull that shrink talk on me!” Instead, ask, “What has kept you from actually getting the
pills [for an overdose]?” This will assess the patient’s impulse control. Sometimes there is
another affect underneath the suicidal urge: “I see how despairing you are, but I’m won-
dering if you’re also angry about this?” If the patient can mobilize their anger and see that
they are not trapped without any other options but suicide, it might obviate the need for
hospitalization. Another example: “With all this stress, do you ever think of ending it all?
Or “Some people in your situation would feel trapped and think about suicide. . . . How
about you? Have you thought about it?” These questions can glean more than the cryptic
“Are you suicidal?” that may not be answered truthfully.
For the patient who cannot express their feelings, sharing one’s own reaction can
normalize feelings and teach the patient that these are human emotions. “When you’re
talking about what you’ve been through, I feel very sad. . . . Is that how you feel? Is it pos-
sible that I’m feeling the sadness that you can’t [aren’t]?”
An Initial Approach to the Emergency Evaluation 13
Underlying the grandiosity of a manic patient is one who unconsciously believes that he
has little merit. You need to ally with the grandiosity. Allow them to tell you how grand
they are. “How do you sleep doing all the [creative/important] things you are doing? You
sound quite [energetic/busy/productive/pressured] to work as fast as you can/in need of
getting your ideas out quickly because of their importance.”
Manic patients dislike an interviewer who is not as fast as they are. They may be per-
turbed that the interviewer is not following their train of thought quickly enough and
may accuse the interviewer of being “stupid.” Acknowledge this: “’I’m sorry I’m not
keeping up with you, and it is frustrating when I’m so slow, but please try to put up with
me, OK?”
The personality disordered patient has ingrained patterns of behavior that the patient
uses to get what they needs or wants.3 The patient does not know any other way of
behaving. It is worth remembering this because the personality disordered patient can
seem as irrational as a psychotic patient and test the patience of even the most skilled
interviewer.
Narcissistic patients have a lack of self-esteem, but it is difficult to sympathize with
that part of them when you are being assaulted by their narcissism. Ally with the narcis-
sism as best you can:
I understand that you have reasons to believe that [an opiate] is what you need right
now, and that you are in tremendous pain, but unfortunately I don’t agree with your
conclusion so I will not be able to prescribe that. But how about [Y]?
If the patient tries to wear you down, repeat your decision one last time and then (with
Security if necessary) back out of the room. Do not get pulled into the patient’s attempts
to wear you down and pressure or frighten you into giving them something that is not
warranted.
The borderline patient in crisis may be hostile or agitated. Interviewing techniques
for the agitated patient are discussed below. It is worth remembering that their emo-
tional dysregulation is often the result of impaired attachment due to childhood neglect
or trauma. Knowing this can help the clinician feel sympathy for the patient, which helps
the clinician be more empathic.
Much has been written about verbal de-escalation of the agitated patient and the dif-
ferent presentations of agitation.3,17 Agitation falls on a spectrum that can move from
anxiety all the way to violence. The patient’s attitude toward the examiner can become
the whole focus of engagement and makes establishing rapport and understanding the
problem challenging.
14 Emergency Psychiatry
A patient must be cooperative for the evaluation to take place. To calm a patient, offer
creature comforts such as food, a drink, or blankets. Ask the patient if there is a medica-
tion they use when this upset. This gives the patient control. Listen for real-life issues that
can be solved: calling a friend to care for a pet or securing the patient’s belongings before
they are discarded.3 Acknowledge and normalize feelings. Agree with what you can and
agree to disagree with what you cannot. An example is the patient who is angry because
he needed to wait a long time to be seen. Without getting into explanations, a simple “I
don’t like to wait either” acknowledges the patient’s grievance and normalizes the feeling.
Keeping the interview brief, taking time-outs, and returning for another short exchange
even several times may be preferable.3 Emergency work requires flexibility and creativity.
Another approach is to reveal one’s own emotional reaction in a judicious manner.
(See Vignette 1.3.) The patient who is perturbing the clinician should be met with an
interpretation or even a confrontation, which needs to be said without any trace of a
punitive or angry tone: “I feel like I’m being dragged into a fight with you. Is this what
happened this morning when you tried to drive the other car off the road?” Another
approach might be, “I’m feeling annoyed by this conversation, and need to step out
to calm down so that we don’t end up arguing.” The patient might be surprised and
sometimes aghast that the clinician is impacted by what the patient is saying. Many
boisterous or argumentative patients believe that loudness and pushiness are the only
way they can have impact; otherwise, it is as though they do not exist, let alone being
taken into consideration. This self-disclosure models appropriate management of feel-
ings. If the patient is aghast and says, “You’re the doctor, you’re not supposed to get
mad,” the response can be that you are human and have feelings too. Self-disclosure can
be extremely useful in the emergency interview and does not have to compromise the
clinician’s authority. It must be used judiciously. None of these techniques are useful
when the clinician has already become furious with the patient. Recognizing when one
is becoming or on the way to being annoyed or angry is when to use these techniques.
Fishkind3–5 outlines 10 rules or “domains” that go into an interaction with a volatile
patient to de-escalate the situation. They are summarized in Box 1.1.
Vignettes 1.1–1.3 provide examples of interviews with an agitated, hostile patient that
demonstrate some skills to use to diffuse a tense situation.
Vignette 1.1
Vignette 1.2
Patient: I don’t want to see shrinks you’re not coming near me get the F out of
here!(The patient is shrieking, waving his hands. Security is on standby. The clini-
cian attempts to establish verbal contact, but it is not possible. The clinician asks
what he would like to see happen in the ED.)
Patient: None of your business.
Clinician: Really? But you’re angry here in the emergency room so it is my
business.
Patient: Then I just don’t want to talk to you. But if I did, I would tell you to get away
from me. I would tell you that I’ll never talk to you! I’ll never say a word in this
place! I want out of here! You hear me you *x*x. (The patient escalates with insults
but remains in behavioral control.)
Clinician: Is there anything that would help you feel calmer? Some juice? A blanket?
Is there any medication that might help take the edge off?
Patient: No.
Clinician: Well, let’s take a break and I’ll come back and hopefully you can talk to
me. (The clinician does not suspect psychosis; the patient appears to be able to re-
main in behavioral control. Taking breaks can be useful as long as the patient is
being watched. Breaks help decrease the potential for argument between clinician
and patient, and they give some time for the patient to cool down and perhaps then
be able to put into words what he is so intensely feeling.)
16 Emergency Psychiatry
Vignette 1.3
Another scenario, same patient. The patient draws the interviewer into an argument.
In this scenario, the clinician is flexible but at the same time firm and respectful. She
tells the patient the conditions with which she will continue to engage with him (her
“working conditions”)18 or “laying down the law.”4,5 She has set these conditions in a
respectful but firm manner. She is clear about the need for safety and civility; she is
willing to be flexible and take breaks yet remains firm regarding acceptable behavior.
She uses self-disclosure to facilitate alliance building and to help the patient feel that
he is among other humans—not at the mercy of rigid authority.
competence, age, or even personality, appearance, gender, or race. Some may be seduc-
tive and attempt to ingratiate or bully the clinician to give them something that they
want. Other patients may touch on the therapist’s own losses or reawaken memories of
one’s own traumas. At these times, the clinician needs to feel the affect, empathize with
the patient, acknowledge their own feelings, and then pull back and reengage the intel-
lect: “What hypothesis does this information generate?” “How can I use this information
and my feelings to better understand and respond to the patient appropriately?” There is
also the need to be aware of both implicit and overt bias that all clinicians bring to clin-
ical encounters.19
It is worth noting that countertransference responses are not always negative. One can
identify with a patient, and that can help build rapport. At other times, overidentification
is problematic. Whatever the response, recognizing the feelings and being able to use
them effectively increases the chance of an alliance.
Mistakes happen to the best clinicians. Patients do forgive us when they sense that we
have their best interests in mind. Hilfiker20 poignantly discusses a case in which a terrible
mistake was made and the parents of a lost pregnancy forgave the doctor when he could
not forgive himself.
Perhaps the biggest fear of the psychiatric clinician is that a patient released from the
ED will commit suicide. No clinician or screening scale can predict suicide. However, a
climate of total risk aversion infantilizes the patient and can create iatrogenic depend-
ency on the emergency and hospital system. It teaches patients that they are not in charge
of their own lives but that clinicians are in charge. Kernberg reminds us that good treat-
ment comes with risk. The goal is to minimize that risk, not eliminate it. Chapter 4 dis-
cusses the suicidal patient in greater detail, and Chapter 21 focuses on high-acuity risk
assessment.
As noted above, interpreting prematurely, not setting limits, and insufficient backup
are problematic. Confrontation can be a useful technique but must be used judiciously.
Impatience and lack of time usually disrupt the alliance. Rushing in too quickly with
focused questions may cause the patient to feel challenged or accused. Apologize, pull
back to less affect-laden topics, and then later return to the charged area to determine if
the patient is now willing to talk about it. “Can we go back to . . .?” As noted previously,
the opposite is also true: Dwelling too long on building an alliance when one has already
been formed can annoy the patient and have the opposite effect.
Interpreting prematurely or assuming that you know how the patient is feeling can
also be problematic. Thus, “you must feel very sad about the death of your mother” might
be met with “Are you crazy? I hated her! You’re not listening to me!” This is an example of
an empathic failure.
Emergency rooms or any medical encounter can induce shame.21 Patients who feel
ashamed or humiliated will not easily form an alliance. It is my view that humilia-
tion can be as traumatic as any tangible event and can severely decenter a person.
Again, a trauma-informed approach helps decrease the likelihood that such an error
will occur.
Confrontation can be a useful technique but must be used judiciously so as not to be
punitive or humiliating. When the patient has successfully managed to anger you, there
18 Emergency Psychiatry
Safety
Lack of adequate backup staff
Trying to engage the patient when the patient tells you to get out of the room
Alliance
Failing to be trauma-informed
Assuming an alliance prematurely
Asking direct questions that may be challenging too soon in the interview
Dwelling too long on establishing an alliance when one already exists
Trying to dissuade a fixed belief or a delusion
Inadvertently humiliating the patient
Making assumptions/empathic failures
Clinician’s Attitude and Behavior
Arguing with the patient
Being judgmental, provocative, or argumentative
Setting limits when one is angry/being punitive or threatening
Impatience and time pressure
Adapted from Richmond.7
is a tendency to lapse into irrational thinking along with the patient. A neutral tone is
best, as is having Security behind you to enforce the limit: “If you try to leave the ED,
Security will stop you.”2,3
Box 1.2 outlines some common interviewing mistakes.
Emergency work can be exhilarating, but much trauma and loss pass through the av-
erage ED. Witnessing and experiencing chronic exposure to trauma can bruise any cli-
nician, even experienced ones. Identifying with a patient’s grief or sense of horror can
also be painful for the clinician. The more exposure to trauma, the more potential for
the development of stress-related disorders. It is referred to in the literature as secondary
traumatization, vicarious traumatization, or compassion fatigue.22
The skilled clinician understands this type of constant exposure is an occupational hazard;
it can be treated, leading to increased resiliency and empathy. Decreasing exposure by having
some designated time for administrative or other clinical duties outside of the ED is recom-
mended. Debriefings with other ED staff about difficult patients is a good idea, despite the
inherent time problems. It is well worth it to carve out a regular time to meet, even over lunch.
Secondary traumatization is different from burnout because it is not the result of excessive
exposure to traumatic events but, rather, to medical systems that do not support their staff,
issue unreasonable demands on clinicians’ time, and even make demands that the clinician
may experiences as a “moral injury.”22,23 Whereas secondary traumatization includes a per-
sonal sense of failure, social isolation, intrusive thoughts of the traumatic event, and even
a sense of moral injury, burnout leads to cynicism, disillusionment, irritability, and anger.22
An Initial Approach to the Emergency Evaluation 19
There is an emerging literature describing the unique skill sets and temperament best
suited for emergency psychiatry work.14,24,25 The temperament of the successful emer-
gency psychiatric clinician is that of an authentic, flexible clinician who possesses
advanced interviewing skills. The clinician should be nondefensive, able to use coun-
tertransference skillfully, spontaneous but judicious with self-disclosure, and able to tol-
erate ambiguity. The clinician must be comfortable making rapid and accurate clinical
decisions with limited information and thrive in an environment that can be chaotic. In
addition, the clinician needs to be authoritative without being authoritarian2 and have a
strong understanding of medical illnesses, particularly those that can present as behav-
ioral emergencies.14
Although ED work is not the same as doing psychotherapy, psychotherapeutic theory
is often called upon for diagnostic purposes and treatment of crises. A psychodynamic
and object relations theoretical base can assist in alliance building. Understanding
the underlying dynamics of the patient’s situation can inform outcome and even risk
assessments.
Conclusion
This chapter gives the beginning emergency psychiatry clinician theory and tools to con-
duct an effective emergency interview. The use of self is essential, and being direct and
flexible enables the building and sustaining of an alliance. This chapter offers a different
paradigm for the emergency interview by thinking less in terms of narrow diagnostic
categories and using a broader, more comprehensive model that allows for establishing
rapport and building alliances.
References
1. Thrasher T. The field as a master class in interviewing. Psychiatric Times. January 29, 2021.
2. Berlin JS. Collaborative de-escalation. In: Zeller SL, Nordstrom KD, Wilson MP, eds. The
Diagnosis and Management of Agitation. Cambridge University Press; 2017:144–155.
3. Richmond JS, Berlin JS, Fishkind AB, et al. Verbal de- escalation of the agitated pa-
tient: Consensus statement of the American Association for Emergency Psychiatry Project
BETA De-escalation Workgroup. West J Emerg Med. 2012;13(1):17–25.
4. Fishkind A. Agitation II: De-escalation of the aggressive patient and avoiding coercion.
In: Glick RL, Berlin JS, Fishkind AB, Zeller SL, eds. Emergency Psychiatry Principles and
Practice. Wolters Kluwer; 2008:125–136.
5. Fishkind A. Calming agitation with words not drugs. Curr Psychiatry. 2002;1(4):32–40.
6. Berlin JS. The modern emergency psychiatry interview. In: Zun LS, Nordstrom K, Wilson MP,
eds. Behavioral Emergencies for Healthcare Providers. Springer; 2021:39–47. https://doi.org/
10.1007/978-3-030-52520-0_3
7. Richmond JS. De-escalation in the emergency department. In: Zun LS, Nordstrom K, Wilson
MP, eds. Behavioral Emergencies for Healthcare Providers. Springer; 2021:221–229. https://
doi.org/10.1007/978-3-030-52520-0_21
20 Emergency Psychiatry
Introduction
The management of agitation is one of the most challenging and stressful elements of
psychiatric emergency care, both for trainees and for more experienced clinicians and
staff. It is crucial to comprehend all the components of agitation because it may por-
tend a life-threatening emergency and can lead to physical aggression and harm to self
and others. There has been a significant evolution in the understanding and treatment
of agitation that is briefly reviewed here. However, the primary goal of this chapter is to
provide practical tools to utilize in the management of agitation, from early recognition
to skills for handling severe aggression. Case vignettes are included to highlight various
types of agitation, each with its own nuances and challenges. The chapter first provides
background information about clinical agitation. Then it discusses how to optimally as-
sess an agitated patient, and it offers a guide for verbal de-escalation, medication-based,
and physical interventions. Because pediatric agitation necessitates its own specialized
approach, see Chapter 15 for further details.
Background
management; those with delirium need an emergent medical workup; those with de-
mentia may benefit from a reduction in stimulation; and so on.
Early Intervention
Mentation
inattention
confusion
increased response Behavior
to stimuli
restlessness
aimless movements
repetitive movements
Speech jaw clenching
excessive talking hand wringing
repetitive phrases hand clenching
loud volume pacing
shouting posturing
cursing assaultiveness
hitting
punching
Affect kicking
irritable biting
hostile
belligerent
uncooperative
disruptive
Maintenance of Safety
Verbal De-Escalation
Although identification of the etiology of the patient’s agitation is a primary goal, verbal
de-escalation remains a first-line intervention for agitation regardless of the cause.
Verbal de-escalation skills can be learned and practiced, and they are critical to safe and
productive clinical engagement.
Project BETA identified four main objectives in working with agitated patients:5
1. Ensuring the safety of the patient, staff, and others in the immediate environment
2. Empowering the patient to manage distress and emotions in an effort to regain
control of their behavior
3. Avoiding usage of seclusion or restraint
4. Reducing the risk of further escalation of agitation
Evaluating and Managing the Agitated Patient 25
Case Example
Mr. O is a 27-year-old male with a history of depression who presents for suicidal ide-
ation. After careful evaluation, he is believed to warrant inpatient hospitalization for
safety and stabilization despite his desire to go home. He has never been hospitalized
before. Several minutes after being told of this decision, a nurse expresses concern about
Mr. O’s state, noting he is pacing the room, loudly mumbling to himself, and repeatedly
requesting to speak with someone.
Observations from the nurse raise concern for escalating agitation in the setting of in-
voluntary hospitalization. Behind the scenes, the team prepares for engagement, alerting
appropriate support and security staff of the situation while choosing one individual to
lead the encounter. They discuss potential scenarios, including what to do if Mr. O’s ag-
itation escalates. The chosen team leader then enters the patient’s room, respecting Mr.
O’s personal space, maintaining appropriate distance, and aware of his own body lan-
guage and tone of voice. The provider knows it is rarely helpful to raise one’s own voice
in such cases.
Dr. X: Hello Mr. O, I’m Dr. X, the psychiatrist you spoke to earlier. Your nurse informed
me that you wished to speak again.
Mr. O: (pacing, wringing hands, speaking quickly)Yes, I need to go home, I came in for
referrals, and now I’m being held here, I just need to go home, this isn’t happening.
Dr. X: I understand your preference is to leave the hospital, but at this time that is not an
option due to concerns for your safety.
Mr. O: (yelling) I can’t, I’ll be fine, I don’t need to be in the hospital! I’m not going into the
hospital!
Dr. X: I know it must be frustrating to feel like your preferences aren’t being heard. But
our goal is the same as yours: to keep you safe, which is why we feel you need to spend
some time in the hospital.
26 Emergency Psychiatry
When verbally engaging an agitated patient, it is paramount to remember they can have
difficulty processing information and become easily confused. The primary communi-
cator should use basic, concise phrases and repeat themself when necessary to convey
important points and set limits. Giving the patient sufficient time to process new infor-
mation is also important. Throughout the interaction, Dr. X attempts to identify and
reflect the patient’s wants and feelings, listening actively to what the patient is saying and
making supportive comments.
Mr. O: (sits down, exasperated, still talking loudly) I can’t believe this is happening to me,
my friend came to the hospital with the same problems, and she left with a therapist!
That’s all I need, I should be able to leave too!
Dr. X: I believe anyone who came in expecting referrals and finding they were being hos-
pitalized would feel the same as you: upset and maybe even frightened. We do believe
it is necessary for your safety at this time.
Although the patient and physician disagree on the intervention needed at this time
(hospitalization), finding some agreement, whether through facts, principle, or odds of
the situation, helps validate and enhance the therapeutic alliance. Note that Dr. X still
maintains that hospitalization is necessary.
Mr. O: (hitting his head with his hands, then jumping up and posturing towards the phy-
sician) I JUST DON’T WANT TO BE HOSPITALIZED!
Dr. X: (backing away slightly) Mr. O., I understand this is upsetting for you, but your be-
havior now is scaring me and the other staff. We cannot let you leave the hospital at
this time, but I would like to see if we can find a way to make you more comfortable
now. Would you mind taking a seat so we can talk?
Mr. O: (sits down, cautiously)
Dr. X: Can I get you something to drink, some food, or a phone to call someone?
Mr. O: I’m sorry, I’m sorry, I’m just very scared, and anxious, and don’t know what
to do. I’ll take a water. And maybe a phone so I can let my parents know what’s
going on.
Dr. X: I understand this is a difficult time for you. I am confident with the right care
through hospitalization things will start to get better. Let me get you that water and
a phone. If you feel your anxiety is getting too high, let us know and we can discuss a
medication to help keep you calm while you’re waiting.
As the patient continues to perseverate, he displays further signs of agitation. Dr. X uses
this opportunity to convey the emotions elicited by the behavior, of which the patient
is likely unaware. All the while, the physician sets clear limits while offering choices
and optimism where possible to assist the patient in feeling some semblance of control.
Ultimately, the patient is de-escalated out of the agitated state.
Utilization of verbal de-escalation can improve safety, reduce the use of force, and
models nonviolent problem-solving. If time and circumstances permit, debriefing with
the patient and other staff following the interaction can help with treatment planning
and improving understanding and processes. Premature escalation to interventions
such as utilization of medications can be perceived as dismissive, rejecting, or humili-
ating by patients.
Evaluating and Managing the Agitated Patient 27
Special Populations
From 2006 to 2014, the rate of mental health and substance use-related emergency de-
partment (ED) visits increased 44.1%.7 The primary diagnoses of alcohol-related disor-
ders and substance-related disorders increased 76.3% and 73.7%, respectively. Patients
with substance use disorders and psychiatric comorbidity are higher ED utilizers com-
pared to patients with a substance use disorder but without psychiatric comorbidity.8
The volume of presentations, as well as the fact that intoxication and withdrawal syn-
dromes are frequently associated with agitation, demands that the emergency clinician
must be adept at identifying and treating agitation secondary to substance use. For more
information on the management of intoxication and withdrawal states, see Chapter 8.
Alcohol
Mr. B, a 42-year-old male with a history of depression and alcohol use disorder, volun-
tarily presents to the psychiatric emergency services for suicidal ideation and is seeking
psychiatric hospitalization. His last drink was approximately 36 hours ago. He reveals
that he has been drinking a “fifth” daily during the past few months and that he has been
admitted to the intensive care unit in the past when he stopped drinking. Vital signs
during his initial triage are notable for a blood pressure of 140/95 mmHg and heart rate
of 110 beats per minute. He is slightly diaphoretic and tremulous. His blood alcohol level
is zero, and urine drug screen is negative for all substances. While awaiting psychiatric
hospitalization, he becomes progressively confused, agitated, and appears to be respond-
ing to internal stimuli.
Alcohol-related presentations are frequently associated with acute agitation in the ED.1
An alcohol level, whether through blood alcohol concentration (BAC) or breathalyzer,
should be obtained for any patient suspected of recent alcohol use upon arrival and po-
tentially again as their BAC may continue to rise if the patient consumed alcohol shortly
before arrival to the ED.
When the primary cause of agitation is likely alcohol intoxication, antipsychotics are
often preferred over benzodiazepines due to the risk of respiratory suppression when
benzodiazepines are combined with alcohol.9 Haloperidol (with or without an anti-
cholinergic), olanzapine, and droperidol are all reasonable options, with one large ret-
rospective study demonstrating decreased length of stay with droperidol.10 However,
droperidol may not be widely available on formulary. Compared to haloperidol, olanzap-
ine has a decreased risk of QTc prolongation—an important factor to consider because
chronic alcohol use is associated with hypomagnesemia, which can elongate QTc.11
Alcohol withdrawal should be suspected among any patient who has abruptly stopped
drinking after a significant period of heavy daily alcohol use. Common features of al-
cohol withdrawal include hypertension, tachycardia, diaphoresis, anxiety, hyperarousal,
insomnia, and irritability.12 Onset of severe complications of alcohol withdrawal, such as
seizures and delirium tremens (DTs), can occur within 48–72 hours from the last drink.
Because untreated or undertreated complicated alcohol withdrawal has a high mortality
rate, vigilance is needed to prevent adverse outcomes. Predictors of complicated alcohol
withdrawal (e.g., withdrawal seizures or DTs) include older age, prior history of com-
plicated withdrawal, hypokalemia, and the presence of severe withdrawal symptoms
28 Emergency Psychiatry
despite high BAC.12 Individuals with this history in addition to significant signs and
symptoms of withdrawal require medical management.
ED clinicians will be responsible for initiating treatment because prompt control of
withdrawal reduces the incidence of adverse events.13 When agitation is associated with
alcohol withdrawal, benzodiazepines are the preferred treatment, with lorazepam, diaz-
epam, and chlordiazepoxide frequently used and no single benzodiazepine demonstrat-
ing superiority.14 Diazepam and chlordiazepoxide are longer acting benzodiazepines
and may provide a smoother detoxification; however, because both chlordiazepoxide
and diazepam are hepatically metabolized, lorazepam may be preferred in patients with
liver disease. All patients receiving benzodiazepines should have their vital signs serially
monitored because instability can portend a worsening condition.
Benzodiazepines
Similar to alcohol intoxication and withdrawal in overall presentation, benzodiaze-
pine intoxication or withdrawal can also be associated with agitation. Benzodiazepine
withdrawal can be life-threatening, with some experts recommending hospitaliza-
tion for withdrawal from very high doses (≥100 mg of diazepam equivalents daily).14
Benzodiazepine withdrawal is treated with large doses of benzodiazepines in the acute
phase (and may be initiated in the ED), followed by a prolonged taper. Treatment of
withdrawal from multiple benzodiazepines should be consolidated to monotherapy
whenever possible, with some preference given toward longer acting benzodiazepines
such as diazepam.15
Opioids
With the current opioid epidemic, patients who use prescribed and illicit opioids have
become more prevalent in EDs. It is important to recognize opioid withdrawal as a po-
tential factor that can exacerbate agitation. Opioid withdrawal can be extremely un-
comfortable, with common physical symptoms of pain, hyperalgesia, insomnia, and
gastrointestinal distress.16 Psychiatric symptoms of opioid withdrawal include anxiety,
agitation, dysphoria, and irritability. The chronology of opioid withdrawal is highly var-
iable depending on the type of opioids used and the presence of adulterants, although
withdrawal symptoms typically start within 12 hours of last usage and peak within 36–72
hours.16 Although opioid withdrawal is rarely life-threatening,17 it should be treated in
order to keep the patient comfortable and reduce the risk of agitation. Treating a patient’s
opioid withdrawal may also help with alliance building and facilitate disposition to ei-
ther psychiatric or substance use treatment.
Treatment of opioid withdrawal with either buprenorphine or methadone is quickly
becoming the standard of care.17 However, the logistics of providing medication-assisted
treatment in the ED is complicated and largely dependent on addiction treatment ser-
vices available within the hospital system. If buprenorphine or methadone are available
treatments in the ED, these options should be pursued because there is evidence that
ED-initiated medication-assisted treatment significantly increases engagement in ad-
diction treatment.18 Non-opioid pharmacologic treatments such as loperamide, meto-
clopramide, and ondansetron can be used to treat gastrointestinal distress associated
with withdrawal.17 Alpha-2 agonists such as clonidine and lofexidine can treat auto-
nomic hyperactivity from withdrawal and may have an anxiolytic effect; patients should
be monitored for signs of hypotension.16 Pain-reducing medications such as ibuprofen
Evaluating and Managing the Agitated Patient 29
can assist with headache and other types of pain, and in some cases, benzodiazepines can
be utilized to calm agitation and anxiety.
Stimulants
Mrs. S is a 25-year-old female brought to the psychiatric emergency services by law en-
forcement in the middle of the night for evaluation of psychosis and agitation after she
was found yelling at bystanders in a convenience store. She is unable to cooperate with
initial triage assessment due to mood lability. She can be heard from a distance yelling
about being abducted by aliens. She is visibly disheveled with poor dentition and is ac-
tively picking at her skin. She accuses the medical team of stealing $300,000 from her and
tries to punch nursing staff before being physically restrained.
Acute and chronic use of stimulants, such as methamphetamine and cocaine, can
lead to delusions, grandiosity, paranoia, and perceptual disturbances.19 Compared to
cocaine, methamphetamine may cause more severe psychotic symptoms, potentially
due to neurotoxic effects and different mechanisms of action. A systematic review
found that methamphetamine-related presentations were more likely to present with
agitation, aggression, and homicidal behavior compared with other substance-related
presentations.20
Benzodiazepines are considered a first-line treatment for stimulant-related agita-
tion.9 There is a dearth of quality studies on the treatment of stimulant-related psychosis,
with some evidence supporting the use of haloperidol, olanzapine, and quetiapine.21
Antipsychotics may be considered if psychotic symptoms are prominent or if benzodiaz-
epines are ineffective.
Phencyclidine
Phencyclidine (PCP) is a synthetic compound with anesthetic and hallucinogenic prop-
erties and is frequently associated with agitation. A 2015 case series found that the most
common presenting symptoms of PCP intoxication included horizontal and vertical
nystagmus, agitation, and retrograde amnesia.22 No high-quality studies have compared
treatments for PCP-related agitation. Most patients only require supportive care and
decreased stimuli (quiet room and dim lights), although the availability of a calm envi-
ronment is limited in some settings. For more severe agitation requiring chemical and
physical restraints, benzodiazepines (lorazepam or diazepam) are preferred and have the
additional benefit of reducing PCP-induced hypertension and seizures.23 There is evi-
dence for using haloperidol for PCP-induced psychosis,24 although it is recommended
to utilize benzodiazepines as first-line and reserve antipsychotics for adjunctive pur-
poses or for prominent psychotic symptoms.25
Nicotine
Nicotine withdrawal may cause agitation, and a thorough assessment of nicotine use
should be included in the patient evaluation. It is important to assess the use of not only
combustible cigarettes but also all forms of nicotine, including e-cigarettes, chewing to-
bacco, and nicotine replacement therapy (NRT). A randomized controlled trial found
that smokers with schizophrenia demonstrated significantly less agitation if they were
treated with NRT.29 Being proactive in offering NRT to all patients who use nicotine is
recommended because they will likely develop withdrawal symptoms if their visit to the
ED is prolonged.
Personality Disorders
For individuals with a known or suspected personality disorder, the approach to agita-
tion requires due consideration of what may be more or less effective, while maintaining
general principles of agitation management. The focus here is on the two most prevalent
types of personality disorders seen in the ED: antisocial personality disorder (ASPD)
and borderline personality disorder (BPD).30
immediately. As the nurse approaches Mr. V with the medication, he becomes more agi-
tated and begins to gesticulate wildly, saying this is all “triggering” him.
Given the prevalence of individuals with BPD presenting to EDs and the unique as-
sociated challenges, special considerations are necessary to optimize management.32
Given that emotional dysregulation and self-harm behaviors are core features of the
illness, staff often use benzodiazepines and antipsychotic medications to calm the
patient.31 These measures are sometimes necessary if a patient is so agitated or anx-
ious that the evaluation cannot take place, but quite often, active validation and verbal
de-escalation are effective and sufficient. Perhaps more than others, BPD patients can
benefit from clinicians talking with them, helping them understand that the staff is
there to help and validating their distress. In many cases, this approach can lead to
rapid stabilization.
It is easy for staff to become dysregulated around BPD patients, particularly if the pa-
tient exhibits provocative behaviors. If these staff emotions go unchecked, it can lead to
hostility or dismissiveness toward the patient that, due to the interpersonal hypersensi-
tivity inherent in BPD, can undermine the therapeutic alliance and further complicate
arriving at an ideal disposition.33 Given that experiences of trauma are common in those
with BPD, care must be taken not to retraumatize the patient with aggressive actions.
A thoughtful and trauma-informed approach is crucial here, attending to elements such
as allowing the patient to have choices to maintain a sense of control and attempting to
understand what the patient needs to feel safe.
Mr. A is an 85-year-old male with Alzheimer’s disease who is brought to the ED by his
wife and daughter for a 1-week-long history of worsening confusion and irritability. His
family became concerned today after he was unable to remember his wife’s name and
waved his cane at her in a threatening manner. He has also been talking about seeing his
deceased brother in the home. His vital signs are notable for a low-grade fever. A brief
neurologic exam appears normal. He appears anxious and afraid. While obtaining a
medication list from his family, the physician discovers that the family has recently been
administering diphenhydramine at bedtime to help with sleep.
Behavioral disturbances due to delirium and dementia are commonly associated
with agitation. Distinguishing between chronic symptoms of dementia and more acute
symptoms of delirium is crucial to a comprehensive emergency evaluation. It is impor-
tant to note the time of symptom onset (hours to days in delirium and months in de-
mentia) and level of arousal (often impaired in delirium and more stable in dementia),
which may provide useful clues. Treatment strategies for agitation associated with de-
lirium and dementia are reviewed here together because there is significant overlap and
they often present concurrently with baseline cognitive impairment and superimposed
mental status changes. The recognition of possible delirium is key, with specific attention
to potential etiologies or precipitating factors including infection, trauma, pain, sub-
stance use, medication changes, and medication side effects. Physical exam, vital signs,
and laboratory findings should augment the history-taking process. Life-threatening
causes or those requiring further medical evaluation and/or intervention need to be
ruled out. When the likely source or sources are found, then mitigating strategies can be
implemented.
32 Emergency Psychiatry
Ms. T is a 54-year-old female with a history of schizophrenia who presents with police
after being found walking aimlessly in the cold for several hours without shoes. During
triage, she appears restless, wringing her hands and pacing, talking despite being alone
in the room. When approached to check her vital signs, she stares intensely and takes
prolonged periods of time to answer basic questions, irritably mumbling that she cannot
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that venerable humbug to exhibit the contents to his guests. The
sight of so much riches naturally inflamed the already excited
cupidity of the Wa’G’nainu. The next step was easy. In spite of Bei-
Munithu’s lukewarm remonstrances, they helped themselves liberally
and departed, exulting, to their villages. The next day El Hakim
unexpectedly arrived, and, entirely unaware of what had taken place,
asked that his trade goods should be brought out for his inspection,
as he wanted to take them over to M’thara. Bei-Munithu, with many
excuses and much wringing of hands, detailed the events of the
preceding day. El Hakim was exceedingly wroth, and he there and
then wrote me the note which had brought me over.
After Bei-Munithu had retired to his village we talked matters over.
El Hakim was very much annoyed at the turn of affairs, and assured
me that this was only one of the unpleasant results of our reverse in
Embe. What others were in store for us, time alone would disclose.
We decided before we turned in that we would go early on the
morrow to G’nainu and demand our goods. We wished to proceed
on the principle of suaviter in modo rather than fortiter in re, but if the
former failed we were determined to apply the latter without
hesitation. El Hakim had taken an inventory of the missing goods,
and found that more than four loads had disappeared. Bei-Munithu’s
conduct in the affair was not above suspicion, but we could not
afford to quarrel with him just then.
At night a bed of banana leaves was made up for me on the
ground in El Hakim’s tent, which, with the addition of a couple of
blankets, made me as comfortable as possible under the
circumstances. My well-earned rest, however, was soon disturbed by
the field-rats, which used me as a playground, and continually
skipped and jumped over my body and face, to their own infinite
amusement and my extreme discomfort. Two or three times during
the night I woke up and found a large rat curled up fast asleep in the
hollow of my neck or under my arm. El Hakim awoke at my frequent
and somewhat profane exclamations, and gently inquired what was
the matter. When I held forth on the drawbacks of slumber in the
savage wilds, he feigned polite incredulity, and remarked, “Shocking,
shocking! Most unfortunate delusions! Very regrettable, Hardwick,
very;” and turning over in his blankets, he added insult to injury by
chuckling audibly at intervals for an hour afterwards, in a most
aggravating manner.
At four o’clock next morning we roused our fourteen men, and set
out for G’nainu, some twenty or thirty of Bei-Munithu’s men
accompanying us. It was rather a rough tramp, the country being
very hilly and much cut up by ravines and streams. We crossed the
river Kazeta (which flows in a south-easterly direction through Zura
at an average altitude of 5000 feet) by a tree-trunk bridge, and at
seven o’clock reached the first village of the Wa’G’nainu and halted
outside. Our men waved green branches as a sign that we came in
peace, but got no answer, the village, which was very strongly
fortified, seeming to be entirely deserted. It was situated on the crest
of a forest-covered hill, and was surrounded by a very massive outer
stockade of roughly hewn tree-trunks with pointed tops. Inside there
were two additional stockades of pointed logs, and the huts within
were also stockaded one from the other, the whole forming a position
almost impregnable to an enemy without firearms. We waited for a
while, but were unable to get any answer to our signals, and held a
consultation to decide on our next move, but in the middle of the
discussion a shower of poisoned arrows from the surrounding bush
winged their destructive way into our midst, killing three of Bei-
Munithu’s men outright; at the same time the now familiar war-cry
rose on all sides, and resounded from hilltop to hilltop in a manner
which showed us that we were fully expected.
The natives, we found afterwards, had driven off most of the stock,
which, with all their women and children, was safely out of the way
on the hills, while their husbands and fathers contentedly settled
down to a comfortable day’s fighting with the Wasungu, with the
prospect of a nice little massacre afterwards as a fitting conclusion to
a most enjoyable day.
We were compelled to quickly decide upon our course of action,
as the Munithu men were wavering, and their desertion would have
meant disaster, they alone knowing the paths. Retreat was not to be
thought of, as, taken in combination with the Embe reverse, it would
have confirmed the natives in their opinion of our helplessness, and
our prestige would be hopelessly lost. Our men summarily settled
the question by firing a volley into the surrounding bush in reply to
fresh showers of arrows. We were now in for a large-sized quarrel,
and as we did not see any immediate prospect of recovering our
pillaged goods by pacific means, we determined to avail ourselves of
the opportunity to recover at least their value, and also to punish the
treacherous Wa’G’nainu for their unprovoked attack. Accordingly we
gave the word of command, and our little force advanced at the
double and captured the village without encountering any serious
opposition. Inside were a few goats and sheep that had been left
behind in the general stampede which occurred when our arrival was
first signalled. The enemy had drawn off for reinforcements, and
meanwhile contented themselves, after the native fashion, with
shouting insulting remarks, together with a list of the various surgical
operations they later on intended performing upon our persons.
El Hakim mustered our men in the village, and divided them into
two parties, one of which he placed under my command, with orders
to forage round for more live stock, while he, at the head of the other,
held the village as a fortified base.
When I was about to select the men I required, we discovered, to
our consternation, that there were only nine instead of fourteen!
Questions elicited no information as to the whereabouts of the
absentees. It was that firebrand Sadi ben Heri and three or four of
his particular cronies who were missing. I had seen them only ten
minutes before, but where they had gone after we captured the
village I could not ascertain; however, we trusted they would turn up
all right. I took five men of our own and about a dozen of the
Wa’Munithu to try to capture some more stock in order to balance
our account with the Wa’G’nainu.
They certainly made me work for what little I captured. They
disputed every plantation and every village till I began to run short of
ammunition. Two or three of my Munithu contingent were killed, so
when I reached the next village I burnt it, just to show the enemy that
they had in no way intimidated us by their opposition; a proceeding
which heartened my men wonderfully. It was very hard work. Every
village was perched on an eminence, and in most cases reached by
only one, or at the most two, almost inaccessible paths. I proceeded
all the time at the double, so that my men should not have time to
think about the danger, and after racing up and down several hills as
steep as the roof of a house, I was fairly pumped and streaming with
perspiration, in spite of the comparatively low temperature. I
captured a few head of cattle and a hundred or so sheep and goats
in the course of an hour or two, and burnt four villages in the
process; which proceeding greatly facilitated my safe retirement to
the base held by El Hakim, when I was forced both by lack of breath
and ammunition to turn my footsteps thither.
During my retirement the enemy concentrated in force along my
route, but a few well-directed shots from my ·303 persuaded them
that it was safer to scatter and take cover. I rejoined El Hakim, and
found that he had also gathered a couple of dozen or so additional
goats and sheep, and three or four head of cattle. It was then nine
o’clock in the morning. There was no sign of the five missing men.
The war-cries and howls of the enemy were increasing rapidly in
volume, and it became more and more evident that a determined
effort was to be made by them to prevent our return. Our Munithu
contingent showed unmistakable signs of wavering, so we concluded
that in the interests of our own lives and those of our remaining men
we had better put on a determined front, and fight our way back to
Munithu. We therefore burnt our temporary headquarters, and retired
in good order, trusting that the misguided Sadi ben Heri and his
equally misguided companions had already safely retired by another
route.
After leaving the village the path abruptly descended into a narrow
valley and ascended the opposite slope, winding amid thick bush, in
which large numbers of the enemy had congregated. Our first view
of them was by no means encouraging. The bush seemed alive with
them. We were at once greeted with a shower of poisoned arrows at
long range, which, though they did no bodily harm, badly shook the
nerves of the men; but El Hakim and I put in a little fancy shooting at
200 yards, and order was soon restored. We got safely through that
particular part, but several times in the next mile or so we were
greeted with showers of arrows from concealed natives. A few shots,
however, generally persuaded them that discretion was the better
part of valour.
After a tiring march, with intervals of skirmishing, we reached
Munithu with our captures intact. When we reckoned them up,
however, they barely covered the value of the trade goods stolen, to
say nothing of the expenditure of ammunition and the personal risk
entailed in the collection. We were very tired and very hungry, but
before eating we dispatched native spies to try to obtain news of the
missing men. After lunch we retired for an hour to sleep off the
effects of our unusual exertion.
FOOTNOTES:
[5] Should the reader be inclined to consider my language to be
somewhat theatrical, it must be remembered with whom I was
dealing. I knew my man, and pointed my remarks accordingly.
CHAPTER VII.
RETURN TO M’THARA.
FOOTNOTES:
[6] The sap of this wood possesses certain stimulating qualities,
and is extensively chewed by the natives of North Kenia. I tried it
afterwards, and found it of a somewhat peppery flavour. Its effect
upon me was rather nauseating, and it afterwards gave me a
slight headache.
CHAPTER VIII.
THE START FOR THE WASO NYIRO.