22/04124

~
~

v
~
~
-
~
T

~ -

0, m ,
p director

Batasan Reaksi
Fedel-Craft
alkilasi

Alki/ Asil asilasi

-
-

Tidal alan disubstituen/

masul zika Substituen
medva

Substituen pertama

Sangat EWE
sangat

⑮ Tiedea
Ew
-

-
tan
Kraft

ChsCOCI Al21s
1 ,

>
-

untur para wandan

Protelesi
sulfonasi
protensi dihilang asam
dapat Kondis
hidrolisis buluy/sterik
-

↑ up for

e
<(Crls) ,

-
C-cry
-NUz
HaSOnC
7-No
oh -
HzSOg #NOy /
LT
.

/
>
-
T >
-

R
(
Y
>
-

H+, +28
L I

EDE 0
s 0 -
5
= o = =

6 n -

-
 conc .
=
pehat
.
concentrated
Potensi amina & Hidrousil

or
protensi
CH

on↑ L]-0
.

NaOH , CHyl
/
-
-

⑭ , conc.

deproteksi
RT

Benzenoid

polisilia CEK JUGUS AUTIVATOR (EDE)

deautivator ↑

A Y gunakan sby acran orto

para

in
I
I LS -
&
/
activator

READ
RANTASAMPN
spesi dan e
nar/energi tambalan

takberpasangan
-
menghariman

/CH3

F--=
Ch -
L
hp/
& .
5
uV · C Cla

u
Markov
-
nikov
- ① masuli di

Overview
-
X - tempat yg
HBr

I
. T
alkena Kaya H

Ki
↑
Br

-corn
>
-
anti Markorhinor

percusida
RCO3R
 -
Ne
Lh
-
L
Markovnikov

#
-

perousida
-

+ Hor tampa

T
↳
-

Anti Marnovninof

Semakin dakat peroxide

dan cincin

halogen semakin stabil

SIDAS
-

KMnOq , Of dingin

/7
L
- hMnOa
>
-

dingin
, Of-
#I L on

as bento at

~
on
-

LL X
-

- -
WMnOa ,
OH

x
-

dingin
-
-

Ozonolisis ousidatif

O
E
R O
& 1) Oz , CHyCOcH
I - Il
2) . He On R-ou
un

-
Reduksi Bich
ju

L
Mi
L
7
↳ -
Na 9
L
WHy ,
CH5OH 2

1, 3-Sillo heusadiena

ocH
2

vi

# >

NHs , et OH Fo
9
Lo
L
/ &
Siuloheus-2-en-1-on
-

Benzenadianium r "j -

↳ diazonium

-
nitrogen

on
R Net
sandmeyer
- f

x N L7 I
I
L
-
S I
-y
-X

- /F
LL
al

real
-
STINSI EDE
a
NUKLEOFLIK
AROMATI
ED
membantu
↑

#
Nor or

#
- NatICOscad) n+
/
-
-
~
-
-

-
>
-
+

so
!
-

/NOw
[]
-

on on
T
-

& >
-

NaH [Oy ,
D

Intermediet Meisenheimer

PEMBENTULAN BENZUNA
-

Benzyne
- -

- Br -Br
/ : NH2
LI
-

M F
- -

~
-
L L
>
-

②
& -

-
L-H -
/
2

..
⑦
-

& #ni
dehidrobenzena
-

1
(g)
H
,

y-NH-
L
/-
- &

L 100 -
Not -
& m-

H+
 - -
Es

↳7
S
Mx -
NHw

L
W MnOs
dingin)
,
Cros , HSO o

7O
---4
L
"On
M

- -
# L
--- on

and on
fura
X
X-4
I T
L t 2n -
Lo
1
7
S -
on

-4 I
MMasoano I -4 /on
①
X sulfonasi -
L/ -

L
Ou I
-
- -
L
- or
C -U "
17
~

--
NaOn

Ron * +
Hea
X 150Nat

-
⑭ -
X

Singin X -
a

I J
uMnOu
L
Econ
>
XOH

Li-1
1 I
/
R
-
NMnOu dingin

on -
,
&4
/corr
O X
hi &

UV

Fahaya

X
/ + HeSOY

-n
-

& x -t : N,

Vy
-

ada
hidroharson
benzen /elektrotil
HeSOU
-
Nuz-

Y
-

X
-

&
B) - or &
Or

X t Br-Br - -+ -yo
⑦ dipol terindows
nukleofil elektrotil

mu x
C NH2 + H -
C >
-
CHy-cHz-Nriz-i
nuk leofil

St

&
S-
D .

-
St
Na-on - Mon + NaBr
-

etano
etilbromida Nuc
-
-

Dim
H
↑

E + CHxC

cn
n

Hallana
 Substituti -
elektrolitik aromatik
-

s Et
↓
-

Caromatik 0 C -

CH3

↑
1
II S-
&
El LS
S -S+
2
S CH2
-

H O
Di
F

-
-
Et

[ O
-- -

asam basa
↓
-

X
~
X
X
- -

& -NOz
HNO3
-
-
H2S0a
7
45
Katalis L

↳ antivasi NO-
+

elektrotilik
FINOg
-
+
HeSOx - +O +
HSO
penyumbang
Protonisas proton
>
-
menyediakan proton

HNOy

-
Y alhana Cotten + 2
X +
X
gas O
Bra reagen adisi

- ~ Critten ↓ ileatan tanjenuh

Y alkena Glen

alkuna CnHorn-2

C
, C
⑭
-

gas

25 -

Gir lig CsH8

↓
Callio
solid
 asil

YV
it
C
ri
-

-
-T
-

-7 & &

&
↳

it
reductor
uns Ni
reductor ↓
he -

wat
(Crk)2 in -
Y g
R

T n &
EDE

:
·

&
LiAl
-

X z O
/
ex NaBulaCh ①

j-
7 -
-
Il 7
-N -
LiBHs ↑-v -

0x reductor
↓ LiBHsLN
·

(
mishgr
Leman

L ou
--# I -
Y
7 L
viny

.
(8) M
-

O
OH-

fo
& &

O
+ maon
-

X
ditanya? Gambar/bentin orbital

#11
= #
③ O
d axy
⑳ ②
dxz ③

da y
,

·
O Px &
&
---

·
⑭

X
AL
HALIDA R -

StS
S
Substituti
Nucheptilik
eliminati D) Substrat

- Nunleoiciu/
R X
-

Basa
(E)
(SN) 3) pelarut

I
Conton /
-
kurzgesagt .

CH3
-

C +