SELECTIVE ANALYTICAL QUESTIONS FOR ISC BIOLOGY

Question 1 : Sperms have a tail whereas eggs do not. Why so?

Ans: Eggs in humans are immobile. So sperms have to move in search of the
egg through the female reproductive tract.

Question 2 : Study the given Karyotype

P Q

Which of the following chromosomes carries abnormal gene for

phenylketonuria?

(a)P (b) Q (c) R (d) S

Ans: The labelled parts P, Q, R, S are 9, 12, 1 and XY chromosomes

respectively. The 12th chromosomes carry abnormal genes for phenylketonuria.

[Note: Instead of directly asking the cause, the question is a bit twisted in which
you have to know what a karyotype is]

Question 3 : Briefly describe the process shown by given diagram. Why is this
procedure done instead of traditional IVF?

Ans: ICSI. Sometimes the sperm cannot penetrate the outer layer, for a variety
of reasons. The egg’s outer layer may be thick or hard to penetrate or the sperm
may be unable to swim.
[Note : Make sure to know all the abbreviations viz. GIFT, ZIFT, IVF etc. Give
special attention to the process of Amniocentesis and Cryopreservation.]

Question 4 : Logical sequence :

Note : Similar questions might be given from various diseases and steps in their
mode of transmission and pathophysiology.]

Question 5 : Gametogenesis Flowchart – PAY EXTRA ATTENTION TO

THE PLOIDY at various stages of both Oogenesis and Spermatogenesis.

Spermatogenesis:
Question 6 : How to study a DNA Fingerprinting pattern?
Ans – (c). Claimant Father 2 has more similarity with that of the son as
compared to Claimant father 1.

Scenerio 2 : Look carefully and you will find that ‘Dad 2’ has more similarity to
the ‘Baby’ as compared to ‘Dad 1’.

Note : Related to DNA fingerprinting, PCR techniques and Gel Electrophoresis

should be effectively studied, including why ethidium bromide is used, and
what would happen if it was not used.

Question 7 :

Answer :
NOTE : Definitions to be learned and conceptualised by heart.

Question 8 :

Answer: Since it is an X linked inheritance, an affected son with genotype

(XhY), means that the mother must have at least one allele for haemophilia.
Since the mother is said to be normal, so the mother must be Heterozygous
(XXh). [So, basically, the mother was a carrier, who is considered to be normal,
as the Xh allele gets suppressed by the other dominant X allele.]

Similarly, the grandson is haemophilic (XhY), means that the Xh allele has been
inherited from the daughter. But since the daughter was said to be normal,
suggests that the daughter too is Heterozygous in genotype (XhX).
Question 9: Give reason type questions, for which, knowledge of the topics
are must.

Answer:

Question 10 : Conceptual ‘What if?’ type question.

Question 11 : Experimental questions.

Question 12:

Answer :
Question 13 : Graph study.
Answer:

Question 14:
Question 15 :

Answers:

Question 16 and 17 :

Ans 16 : b

Ans 17 : a
Question 18 :

Answer:

Question 19 :

Answer:
Question 20

Answer: