UNIVERSITY OF LA SALETTE INC.

College of Nursing,

Public Health and Midwifery

Santiago City, Philippines

NURSING
DRUGS DOSAGE CLASSIFICATION ACTION INDICATION CONTRAINDICATION SIDE EFFECT
CONSIDERATIONS

Captopril 25 mg/tab ½ ACE inhibitor Inhibits ACE, It is indicated to It is contraindicated to Paroxysmal cough BUN, electrolytes, serum
tab BID converting treat congestive people with creatinine, and blood pressure
Rash with pruritus and
angiotensin I to heart failure and hypersensitivity to require routine monitoring.
occasionally with fever,
angiotensin II, as left ventricular captopril, any component
arthralgia, and eosinophilia If captopril is initiated in
decreased plasma dysfunction of the formulation, or any
patients with impaired renal
angiotensin II, following other ACEI In terms of angioedema, it
function and/or collagen
leading to myocardial can occur in any region such
Angioedema related to vascular disease, the complete
vasodilation and infarction as the intestine but
previous treatment with blood count with differential
decreased angioedema of the tongue,
ACEI should be evaluated before
aldosterone glottis, or larynx cause
starting treatment and at two-
secretion. obstruction of the airway.
week intervals for about three
Intestinal angioedema- months, then periodically after
abdominal pain with or that.
without nausea vomiting.
Report any signs of infection,
Flushing or pallor including sore throat or fever.

Hypotension Taken 1 hour before meals.

ACE inhibitors may cause

hyperkalemia.

Digoxin 250 mcg /tab Cardiac Glycoside The inhibition of Primarily Contraindicated in CNS: headache, weakness, Monitor apical pulse for 1 full
½ tab BID the sodium pump by indicated for patients with drowsiness, vision changes min before administering.
digoxin increases decreasing Hypersensitivity; Hold dose and notify health
CV: arrhythmias
intracellular sodium workload of the care professional if pulse rate
Uncontrolled ventricular
and increases the heart and GI: GI upset, anorexia is <60 bpm
arrhythmias;
calcium level in the relieving HF.
Closely monitor ECG, Blood
myocardial cells, Heart block (in absence of
pressure, intake and output.
causing an
 UNIVERSITY OF LA SALETTE INC. College of Nursing,

Public Health and Midwifery

Santiago City, Philippines

increased pacemaker); Observe for signs and

contractile force of symptoms of toxicity.
Idiopathic hypertrophic
the heart.This
subaortic stenosis; Before administering initial
improves the left
loading dose, determine
ventricular ejection Constrictive pericarditis;
whether patient has taken any
fraction (EF), an
digoxin in the preceding 2–3
important measure
wk.
of cardiac function..
Do not administer drug with
food and antacids to prevent
decreased in drug absorption.

Furosemide 30mg IV q6, Loop diuretics It mainly inhibits Indicated for Contraindicated in Fluid and electrolyte Correct hypovolaemia,
hold if bp < the reabsorption of the treatment of patients with renal failure imbalance. Rashes, hypotension, and severe
90/60 Na and chloride in edema with anuria not photosensitivity, nausea, electrolyte disturbances prior
the ascending loop associated with responding to furosemide; diarrhoea, blurred vision, to treatment initiation.
of Henle and in congestive heart renal failure due to dizziness, headache,
Monitor blood pressure,
both the proximal failure. poisoning by nephrotoxic hypotension. Bone marrow
serum electrolytes (e.g. serum
and the distal renal or hepatotoxic agents; depression (rare), hepatic
Na, K), renal function, and
tubules. It also dysfunction.
blood glucose levels
interferes with the Hyperglycaemia, glycosuria,
periodically;
chloride-binding ototoxicity.
cotransport system, Measure and record weight to
thereby causing its monitor fluid changes.
natriuretic effect.
Orthostasis, hearing (on high
doses or rapid IV
administration).
Watch out for hypokalemia

Paracetamol 300 mg q4 IV Analgesic; Increases the pain Indicated for Contraindicated in patient Blood and lymphatic system Monitor serum paracetamol
for temp >37.8 antipyretic threshold by the with allergy to disorders: Rarely, anaemia, levels in patients with hepatic
 UNIVERSITY OF LA SALETTE INC. College of Nursing,

Public Health and Midwifery

Santiago City, Philippines

inhibiting two management of acetaminophen; with thrombocytopenia, disease during prolonged use.
isoforms of mild to severe hepatic impairment agranulocytosis.
Assess relief of pain or fever.
cyclooxygenase, moderate pain, or active liver disease
Cardiac
COX-1 and COX-2, the (IV). Report rash, unusual bleeding
disorders: Tachycardia.
which are involved management of or bruising, yellowing of skin
in prostaglandin moderate to Gastrointestinal or eyes, changes in voiding
(PG) synthesis; severe pain with disorders: Nausea, vomiting; patterns.
acting directly on adjunctive redness of rectal mucus
the hypothalamic opioid N-acetylcysteine should be
membranes (rectal supp).
heat-regulating analgesics, and available as a specific
center to cause the reduction of antidote; basic life support
vasodilation and fever. measures may be necessary.
sweating, which
helps dissipate heat.

Penicillin G 1.6 m.u IV q6 Beta-lactam By binding to For use in the Contraindications of CNS: Seizures. Watch for seizures; notify
ANST Antibiotic specific penicillin- treatment of penicillin include a physician immediately if
GI: diarrhea, epigastric
binding proteins severe previous history of severe patient develops or increases
distress, nausea, vomiting.
(PBPs) located infections allergic reactions or seizure activity.
inside the bacterial caused by penicillin and Stevens- Derm: rash, urticaria.
Monitor signs of allergic
cell wall, penicillin penicillin G- Johnson syndrome after
Hemat: eosinophilia, reactions and anaphylaxis,
G inhibits the third susceptible administering penicillin or
leukopenia. including pulmonary
and last stage of microorganisms a penicillin derivative.
symptoms (tightness in the
bacterial cell wall when rapid and Local: = phlebitis at IV site. throat and chest, wheezing,
synthesis. Cell lysis high penicillin
Misc: ALLERGIC cough dyspnea) or skin
is then mediated by levels are
REACTIONS, INCLUDING reactions (rash, pruritus,
bacterial cell wall required such as
ANAPHYLAXIS AND urticaria).
autolytic enzymes in the treatment
such as autolysins; of septicemia, SERUM SICKNESS, Notify physician or nursing
it is possible that pericarditis, superinfection. staff immediately if these
penicillin G endocarditis reactions occur.
interferes with an associated to
 UNIVERSITY OF LA SALETTE INC. College of Nursing,

Public Health and Midwifery

Santiago City, Philippines

autolysin inhibitor. rheumatic fever

disease