180 Dermatology neds enioy 21 ECZEMA Definition 00:00:40 Reaction pattern of the skin secondary to the endogenous (internal) or exogenous (external) stimuli, Morphological classification + | Reute. a, Subacute. 3, Chronic. Aeute eczema? Characterized by call signs of acute inflammation of the skin + + erythema. * Edema. * vesicles. . Oo2zing, . Crusting, Histopathology * Spongiosis : intraepidermal intercellular edema. Subacute eczema ? Characterised by + erythema + Scaling Chronic eczema + tt happens as a response to chronic itching, Lichenification (as 0 result of continuous itching) + *+ Hyperpigmentation. * Thiel skin. + exaggerated skin markings. Dermatology « v4.0 * Marrow 6.5 * 202324 Eczema 181 Btiologie Classification etiologic classification Exogenous Endogenous Contact dermatitis Photodermatitis Phytodermatitis Phytodermatitis + Photodermatitis Contact dermatitis 0 InSlammation of the skin secondary to contact between skin § substance. Two types + Lirritant contact dermatitis. . Aliergic contact dermatitis (CD). leritant CD Allergic Cb Predisposition |APects all who /A*ects genetically are exposed _| predisposed Mechanism | Non immunologic | Immunologic (type Iv Girect tissue hypersensitivity reaction) domage) Distribution | Restricted to the | Tends to disseminate, site of contact | beyond the site of contact symptoms [more burning | more itching examples of irritant CD # Detergents Acids/alkalis 4 i a’ £ 2 a Dermatology « v4.0 * Marrow 6.5 + 2023182 Dermatology neds enioy 21 Diaper dermatitis : Involves convex areas sparing the folds, examples of Allergic CD: Hair dye + PPD (para. phenylene diamine). metal : Nickel (most common). Topical antibiotic : Neomycin. Cement : Potassium dichromate. Bindi : PTEP (para tertiary butyl pheno). Pokch test : Diagnosis of allergic CD. Type of hypersensitivity reaction: Type 4, method : Allergens are applied over the patient’s back § wait for type 4/ delayed hypersensitivity, reaction. Read at : 48 hours/a days. Gest read at : 9% hours/4 days. Airborne contact dermatitis 00:12:38 Disease : Type of contact dermatitis caused by release of substance into air which settles onto the exposed parts of the skin. Plant : Parthenium hysterophorus (congress grass/communist plant). Allergen : Sesquiterpene lactone (SQL). Site : Neck, upper eyelids, face, V areas of chest. Diagnosis : Photo patch test (patch test + uv radiation). Disease: Phytophotodermatitis. The plant chemicals on exposure to sunlight couses dermatitis. Dermatology « v4.0 * Marrow 6.5 * 2023