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United Group, one of the largest Chairman Mr Hasan Mahmood Raja demonstrating social responsibility in the
business conglomerates of the country, shared the aspiration that United Group pursuit of nation building endeavors.
celebrated its 40th Foundation Day on nurtures to take the company forward in
the coming days and he urged every On this occasion, the Board of Directors
12 July 2017. The group is committed to
employee to uphold this goal in a conveyed in their message the immense
socio-economic development of the
homogenous way from every corner; value that they give to their human
country by continuously enhancing
each employee working as an resource & stakeholders being the
value of its stakeholders and striving to
ambassador of United Group. He driving force of the company; they
be a socially responsible corporate
emphasized on maintaining a conducive expressed their pledge to create higher
entity by supporting community engage-
working atmosphere with family bonding opportunities for enhancing their
ment activities.
between everyone; he further stressed contribution and growth in the days to
In his inspiring speech, the Group upon the need to be dedicated in come.
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Issue-19 | Quarter-3, 2017
“The term anteroseptal STEMI neither implies that the No differences were observed between the two groups in
ischemic process is limited to the anteroseptal segments, nor baseline characteristics; except AS-STEMI group had more
that the size of the ischemic area at risk is smaller than that patients with diabetes and EA-STEMI group had more
in patients with extensive anterior STEMI.” patients with family history of coronary artery disease.
Post myocardial infarction (MI) short and long term clinical Comparison of mean of total involved segments and
outcome is largely determined by the size of the infarcted ejection fraction between two groups (n=196)
area. It is generally assumed that as the lead involvement in
electrocardiography (ECG) is less in anteroseptal ST Total Groups
segment elevation myocardial infarction (AS-STEMI), where involved Group I Group II P (95% CI)
ST segment elevation (STE) is limited to leads V1 to V3, segments (n=90) (n=106)
myocardial damage is likely to be less; and in extensive ante-
rior STEMI (EA-STEMI), as the STE extends further upto V6, Mean 8.83±2.49 9.01±2.25 0.604NS
the myocardial damage is likely to be more. This study was ±SD (.492 to .498)
intended to compare regional wall motion abnormality Groups
(RWMA) between acute anteroseptal STEMI and acute Ejection
Group I Group II P (95% CI)
extensive anterior STEMI patients. fraction
(n=90) (n=106)
This cross sectional analytical study was carried out in
Dhaka Medical College Hospital; 90 patients with AS-STEMI Mean ± 38.8±5.78 39.21±5.90 0.627NS
and 106 patients with EA-STEMI, admitted in between Octo- SD 2.059 to 1.245)
ber 2012 and September 2013, were included. For each
patient, a transthoracic echocardiogram (TTE) was Group I (AS-STEMI), Group II (EA-STEMI), P value derived
performed within 24-48 hours of MI and was interpreted by from Student t test. NS = not significant,
an independent investigator blinded to the patient's ECG
data. The left ventricle was divided into 17 segments (6 In conclusion the term AS-STEMI may be a misnomer, as it
basal, 6 mid-ventricular, 5 apical).13 Comparison of RWMA implies that only the anteroseptal segments of the left
between the two groups for each of the 17 segments was ventricle are involved. This study shows that regional
done. Global wall motion abnormality was compared dysfunction in patients with AS-STEMI extends beyond the
between the groups on the basis of ejection fraction (EF%). anteroseptal region.
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Issue-19 | Quarter-3, 2017
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Issue-19 | Quarter-3, 2017
Volumetric Modulated Arc Therapy deliver VMAT delivery with 6MV FFF substantially affected by the gating
(VMAT) replaced a standard form of beam using gated and non-gated windows when evaluated with the
Intensity Modulated Radiotherapy technique. A dosimetric comparison was gamma statistics, suggesting the
treatment (IMRT) in most of the health made between the gated and non-gated interplay effect has a small role in
care set-up due to it’s superior dose delivery using ion chamber matrix and respiratory-gated RapidArc therapy.
distribution with reduced treatment time absolute dosimetry was also performed Varied results were seen when gated
and monitor unit. Intra fraction organ to evaluate the delivery accuracy. therapy was performed on the patient
motion during the treatment delivery is plans that could only be attributed to
one of the major concerns. In this study differences in patient respiratory
we tried to evaluate the accuracy of dose patterns. Patients whose plans had the
delivery with respiratory gated VMAT. largest percentage of pixels failing the
Five previously treated patients (2 gamma statistics exhibited irregular
Hepatocellular Carcinoma HCC and 3 breathing patterns including substantial
Lung cancer) were included in this study inter patient variation in depth of
to evaluate accuracy of the gated VMAT respiration.
dose delivery. All the patients were Regular sinusoidal wave forms using
simulated with retrospective 4DCT. phantom results were within acceptable
Entire respiratory cycle was divided into limits. Gamma evaluation using Imatrix
10 bins or CT datasets (ie. with 3% & 3mm criteria passed >97pixel
0,10,20,30,40,50,60,70,80 & 90). The and the absolute dosimetry were within
MIP (Maximum Intensity Pixel), AIP ±2% for all the patients. These results
(Average Intensity Pixel) and MIN were encouraging and gave us
(Minimum Intensity Pixel) were created confidence that our planned and
from the deep inspiration period (i.e. 90, For regular sinusoidal motion, the dose delivered fluencies were within the
0 & 10). All the patients were planned to delivered to the target was not acceptable clinical limit.
In the past two decades, many impor- (diagnosed in three children in January, risk of its spread. The IEDCR (Institute
tant vector-borne diseases have 2016) and Guillain-Barré syndrome of Epidemiology, Disease Control and
re-emerged and spread to newer parts (later in life). WHO declared the cluster Research) has identified Zika from
of the world. Zika virus is one of them, of microcephaly cases and other neuro- previous stored samples and has
which was first isolated in 1947 from a logical disorders associated with Zika developed national strategy for Zika
monkey in the Zika forest, Uganda; infection a public health emergency of viral disease identification. Training has
since then sporadic cases were international concern (PHEIC) on 1 also been given for health care person-
reported worldwide. In 2015, 84 nel along with finalization of case
countries and territories reported definition of Zika related micro-
evidence of vector-borne Zika virus cephaly. Along with this on-going
transmission. Other than mosquito training progress in Zika identifica-
bite it can be transmitted from tion among health workers, aware-
mother to fetus during pregnancy or ness should be increased among
around the time of birth. Affected common people as well. For
individuals suffer from fever, rash, preventing Zika related micro-
joint pain and red eyes. Usually cephaly and other malformations
disease severity is mild and of newborn we also have to
resolves spontaneously within few ensure and strengthen regular
days to weeks. Intrauterine Zika virus Feb, 2016. Since then the Government antenatal care, examine all infants with
infection causes miscarriage and early of Bangladesh has been addressing microcephaly for proper evaluation of
neonatal death, fetal microcephaly, the iceberg of the problem and has the cause and to enroll birth defect
fetal malformations and neurological already taken some initiatives for Zika cases in the national birth defect
disorders, cerebral calcification, ocular preparedness in our country. Preva- surveillance system to observe the
abnormalities like loss of foveal reflex, lence of the vector Aedes Aegypti mos- trend of these birth defects, identify and
macular neuro-retinal atrophy quito in Bangladesh, adds more to the notify these to avoid disease outbreak.
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Issue-19 | Quarter-3, 2017
Haemolytic disease of newborn (HDN) results from • Introduction of routine antenatal anti-D prophylaxis
feto-maternal blood group incompatibility, most often in ABO (RAADP):
and Rh blood group and rarely in other minor blood group For Rh negative mothers who have not developed antibodies
systems. The pregnant mother develops an antibody against yet, there are currently two ways of receiving RAADP-
fetal red cell antigens that crosses the placenta and causes
destruction of fetal red cells. HDN due to ABO incompatibility 1) a one-dose treatment: where pregnant women receive an
are common, mild and passes on unnoticed in majority of the injection of immunoglobulin at some point during 28 to 30
cases. HDN due to Rh incompatibility, mainly Rh D, are often weeks of their pregnancy
severe and causes clinical problems. 2) A two-dose treatment: where pregnant women receive two
Rh-HDN has the following characteristics: injections; one during the 28th week and the other during the
34th week of pregnancy.
a. In the majority of the cases, the mother is of blood group ‘O’
Rh D -ve and the fetus is of blood group A, B or AB Rh D • Injection of Anti-D immunoglobulin within 72 hours of child
+ve. birth, if the mother is RhD negative and the baby is RhD
positive, and the mother hasn’t already been sensitized
b. It does not usually occur in first pregnancy. The chance of • Decreased number of children reduces the prevalence of
fetal HDN increases with successive pregnancies HDN, as the risk of HDN increases with subsequent
Prevalence of Rh HDN in United Hospital in the last 05 years pregnancies
(April, 2012 – March, 2017) is shown in the following table • Increased awareness, e.g. preferring caesarean section
(Table 1): than normal vaginal delivery result in decreased chance of
Total no of Rh Detection of Rh Severity transmission of fetal red blood cells into mother’s circulation
antibody tests done in Rh antibody antibody of Antenatal checkup for Rh negative mothers having anti-D
UHL lab in last 5 years No. (%) titer HDN antibodies (Rh alloimmunized women):
1:4 Mild - Anti-D antibody titers are typically performed monthly until
217 3 (1.38) 1:8 Mild 24 weeks of gestation, after which period titers should be
1:64 Severe repeated every 2 weeks.
- Pregnancies in which antibody titers are 1:8 or lower can be
While worldwide data are not available, the percentage of
managed by serial monitoring of maternal antibody titers.
presence of Rh antibody in D-negative women alloimmunised
following a D-positive pregnancy in USA in 1960s & 1970s (1) - If the titer is 1:16 or higher, fetal wellness assessment is
is shown in the following table (Table 2): compulsory by ultrasonography to evaluate middle cerebral
artery peak systolic velocity (MCA-PSV) or serial
Year Presence of Rh antibody (%) amniocentesis for delta OD450 (a bilirubin derivative) if the
1960 s 14 former is not available.
1970 s 1-2 - Spectrophotometric analysis of amniotic fluid bilirubin
derivative can be performed to detect the presence of fetal
It is obvious from the above mentioned data that the prevalence HDN and its severity. The amount of delta OD450 in
of the presence of Rh antibody in D-negative women amniotic fluid samples can be used to estimate the degree
alloimmunised following a D-positive pregnancy resulting in of fetal haemolysis.
HDN in subsequent pregnancies has decreased greatly in last
- When fetal haematocrit is less than 30%, detected in fetal
few decades.
blood sampling, the only therapeutic option is intrauterine
Possible reasons for decreased prevalence of HDN are: fetal transfusion.
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Issue-19 | Quarter-3, 2017
“The right product” Purchase department. An approved store will forward it to the purchase
“In the right quantity” purchase order is required prior to the department.
purchase of any goods, capital items,
“At the right price” services, supplies and construction 2. Sourcing: After receiving the
“At the right time” items. purchase requisition, the product is
identified as per user satisfaction
Purchase department needs to actively To avoid fraudulence, wastage and along with brand, origin and suitable
and continuously participate is search- misuse, all concerned staff and procure- price. Then the purchase requisition
ing ideas from manufacturers and circu- ment officials scrupulously and sponta- is approved.
lating suggestions among supply neously follow, enforce and ensure full
sources in the pursuit of achieving cost compliance with the ethics
savings, product improvement and/or & regulations of United
process improvement. Hospital. It is the policy of
The Purchase & Procurement Depart- United Hospital that all
ment of United Hospital negotiates properly approved and
contracts for medical supplies, food, competitively priced
clothing and linen, office supplies and purchase requisitions are
transport equipment such as ambu- processed in a timely fash-
lances. It's a complex job that requires ion, resulting in accurate
constant supervision to ensure appropri- payment through the
ate goods are purchased and adequate accounts payable depart-
inventory levels are maintained. ment.
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Issue-19 | Quarter-3, 2017
3. Vendor Selection:
For regular goods
all vendors are
pre-shortlisted by
the purchase
department. They
must be licensed
to the extent as
required by law. It
is the responsibil-
ity of this depart-
ment to verify
compliance and
the vendor is
considered pre-qualified provided no The commercial unit deals with banking given for a fixed period with an option to
adverse information is identified by & shipping aspects of items that are renew for a specified period depending
United Hospital. imported directly by the hospital to meet on market price fluctuation.
its diversified requirements. Commer-
4. Quotation/Price Offer: After requisi- Occasionally, vendors offer to have their
cial personnel are familiar with CNF
tion is approved, quotation/price equipment used on a trial basis in order
Agents and have knowledge of all rules
offer is collected from vendors to determine its usefulness to a depart-
and regulations of Customs and the
minimum of three wherever ment. When presented with this oppor-
National Board of Revenue which
possible. Quotations must be in enable them to do their work smoothly. tunity, the purchase department tries to
letterhead/ official pad and contain take advantage of such option. Once
detailed specification of product Capital Equipment is defined as equip- the terms have been agreed upon, the
mentioning the manufacturer’s ment with an acquisition cost of BDT department uses the equipment for the
name, origin, pack size, price & price 10,000 (ten thousand) or more and a specified period of time. At the end of
validity etc. Contact person’s name useful life of at least one year. Both the trial period, the equipment is
with phone number is also manda- requirements must be met in order for a returned to the vendor at no cost to
tory in quotation/price offer. product to be considered as capital United Hospital. During selection of
equipment. equipment the purchase department
The purchase policies and proce- reviews the reputation, reliability, capa-
dures of United Hospital promote The Purchase department maintains
bility, experience as well as expertise of
strong internal controls to ensure close working relationship with the the vendor/ supplier; availability of
that only those goods and services accounts department and provide all goods and services as per hospital
approved for purchase are charged assistance with regard to submission of demand; availability of replacement
accurately to specific accounts and bills & documents and any other parts and technical assistance; warran-
meet the requirements/ standards of information/ work that may be required ties offered by the supplier which may
the user department. to complete the post-purchase steps. include service and repair by the
5. Emergency Purchase: An emer- Where appropriate, issuance of supplier; delivery period and cost etc.
gency purchase is defined as the business to competing vendors via The department continuously tries to
purchase of commodities or separate purchase order is done. The ensure that the patients of the hospital
services, regardless of amount, competitive process allows for multiple are provided
where the purchase is made as a contract awards provided all vendors with the best
result of a sudden and /or unfore- agree to adhere to the hospital possible prod-
seen demand. The requesting purchase policy and meet the specific ucts in a safe
department must notify the purchase requirements of the user department. In environment at a
department of the nature of the need some cases, quotations are taken for a c o s t - e ff e c t i v e
for the emergency purchase. fixed period and contract awards are price.
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Issue-19 | Quarter-3, 2017 Issue-19 | Quarter-3, 2017
A 35 years old female presented with a painful lump on lateral Often the lesion appears to be a firm nodule; FNAC becomes
aspect of a pfannenstiel incision 10 months after caesarean the first choice of diagnostic tool which gives a full histological
section. Abdominal examination revealed a firm tender lump picture that helps differentiating it from metastatic disease like
with history of gradual increase in size of 3x3 cm with no desmoid tumor, lipoma, sarcoma, fasciitis, hematoma, abscess
discharge. USG revealed a bright heteroechoic mass followed and fat necrosis. Imaging modalities like USG, CT or MRI has
by MRI revealed extension on external oblique aponeurosis some use but not specific.
and also onto muscle wall. It showed endometrial glands and MRI is much preferred than CT due to its high special resolu-
stromal cells confirming two findings of the pathological triad of tion, MRI detects planes between muscles and subcutaneous
endometriosis. FNAC was done. The scar initially was thought tissues. It magnifies the extensions of affected tissues thus
to be a scar granuloma and treated conservatively. However, as helps planning operative resection especially recurrent and
the lump persisted getting enlarged in size, surgical intervention large lesions.
was done with wide excision of the lump under general anaes-
thesia. The only treatment
modality is Wide
In pathology, fibro adipose tissue with interspersed gland and Surgical Excision of
stroma reinforced the findings of FNAC thus confirming the the lesion of 1cm
diagnosis of Endometriosis. range on all sides and
Scar Endometriosis (SE) i.e. Incision Endometriosis is a rare patch grafting of the
condition; though growing prevalence of gynaecological and fascial defects.
obstetric surgeries has made it an issue to concern. In general, It has been reported
estimated 89 millions women of reproductive age group have that medical treat-
been affected with this worldwide. The prevalence of surgical ment with OCP and
Endometriosis is about 1.6%; yet posing significant clinical progestogen and Surgical Excision Removal of Endometriosis
importance specially with increasing hysterectomy and gonadotrophin
caesarean section, contributing 1.08 - 2% and 0.03 - 0.4% agonist (Leuprolide acetate) has been in use but provides only
respectively. prompt improvement in symptoms which recur on withdrawal of
the treatment. Follow up, is of great importance as chances of
recurrence is high which requires re-excision. Malignant
change is very rare but continual recurrence imposes a threat,
so possibility needs to be ruled out.
Gold Standard Surgical Excision Removal of Endometriosis
Hypertrophied Scar Endometriotic Scar
The aetiology attribute to the direct implantation of decidual
cells during various gynaecological and obstetric surgeries,
which subsequently proliferate or induce metaplasia in the
surrounding cells under the influence of oestrogen.
Diagnosis of SE is always challenging as it may appear after an
interval of 3 months to 10 years of the primary surgery.
Commonest sites being abdominal skin and subcutaneous
tissues through rectus sheath is hardly involved. Symptoms
often mimic common surgical complications like appearance of
painful lump in or around the surgical scar, but in SE the lump
remains persistently enlarged in size or exhibits unsightly, Good technique and proper care during gynaecological and
discolored hypertrophic scar which is severely tender on palpa- obstetric surgeries help preventing Scar Endometriosis. Thor-
tion. Cyclicity of symptoms during menstruation like classical ough cleaning and vigorous irrigation with saline before closure
endometriosis is not always among the findings. in extensive abdominal procedures is highly recommended.
To establish SE presence of 2 out of 3 criteria of pathological Overall good surgical and gynaecological knowledge and
Triad (Endometrial gland, Stromal cells, haemosiderin laden efficient examination helps better preventive and prognostic
macrophages) need to be present along with the symptoms. care.
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Chronic kidney disease (CKD) is a Out of 1463 patients, 169 (11.6%) had (4.4% vs 1.6%), atrial fibrillation (12% vs
predictor of increased morbidity and CKD, this population was older, 6%), low cardiac output syndrome (12%
mortality in patients undergoing off-pump presented greater prevalence of vs 7.2%), longer stay in intensive care
coronary artery bypass surgery hypertension, left ventricular dysfunction, unit (4.84 vs 2.83 days) and greater
(OPCAB). This retrospective study was prior stroke, peripheral vascular disease mortality (8.4% vs 2.4%). Female
conducted to evaluate the characteristics gender, smoking, diabetes and
and predictors of increased morbidity peripheral vascular disease were
and mortality in the CKD population, who associated with higher in-hospital
have undergone OPCAB and to compare post-operative complications and
in-hospital outcomes between patients mortality within the CKD group. Patients
with and without CKD and with and who did not develop post-operative AKI
without development of acute kidney presented 2.4% mortality; non-dialytic
injury (AKI). AKI and dialytic AKI presented 16.7%
and 33.3% mortality respectively.
A prospective analysis was done of all Mortality was directly related to the
isolated OPCAB performed at United stages of CKD.
Hospital from January 2015 to October
2016. CKD was considered when e-GFR In conclusion it can be said that, CKD
was < 90 ml/min/1.73m2. Clinical charac- patients submitted to OPCAB represent
teristics, mortality and post-operative a high risk population, with increased
and triple vessel disease, hence higher incidence of complications and mortality;
complications were evaluated according Euro SCORE. In-hospital outcomes
to renal function and stages of CKD. further post-operative AKI is a strong
revealed greater incidence of stroke in-hospital mortality predictor.
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Issue-19 | Quarter-3, 2017
Scientific Seminars
Date & Venue Programme Title Speakers Remarks
27 July ’17 Chronic Viral Dr Mohammed Mahbub Alam, In
Hepatitis & Its Consultant, Gastroenterology & Hepatology commemoration
United Hospital
Seminar Hall
Management Dr Fowaz Hussain of World Hepatitis
Consultant, Gastroenterology & Hepatology Day
21 August ’17 Capsule Endoscopy Dr Dhakshitha Wickramasinghe To mark launching
United Hospital University of Colombo of Pillicam Capsule
Seminar Hall Endoscopy
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Issue-19 | Quarter-3, 2017
Along with 27 participants from all around the country Sharifun Nahar,
Radiotherapy Technologist of United Hospital attended a 5 day training program on
Radiation Protection for Radiation Workers and RCOs of BAEC Medical Facilities
and Industries, held from 20 to 24 August 2017, arranged by Bangladesh Atomic
Energy Commission (BAEC).
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Issue-19 | Quarter-3, 2017
Chief Adviser Editor-In-Chief Editorial Board Communication Support Graphic Design Printed By
• Najmul Hasan • Dr Shagufa Anwar • Dr Mahboob Rahman Khan • Syed Ashraf-ul-Masum • Jamayet Hossain Russell • Creation
• Hanufa Ahmed • Luna Nasreen Tarafdar