Republic of the Philippines

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF SOUTHERN PHILIPPINES

Alubijid | Balubal | Cagayan de Oro | Claveria | Jasaan | Oroquieta | Panaon | Villanueva

COLLEGE OF SCIENCE AND MATHEMATICS

Department of Environmental Science and Technology

Group no:
Group member:
Bautista, Aljhon G.
Dulangon, Luredel
Gabica, Jessica
Omongos, Charlie
Traya, Faith Love

Course and Section: IT 1R3

GROUP ACTIVITY
Week 10-11
Getting to know Nano

Biomedical Nanorobots
Biomedical nanorobots are highly specialized and miniature devices that must be capable of
performing precise tasks within the human body. Recent advancements in nanotechnology
and materials science have therefore promoted the development of both micro- and
nanorobots for a wide range of biomedical applications.
Biomedical nanorobots are typically produced using nanotechnology techniques such as top-
down fabrication (e.g., lithography) or bottom-up assembly (e.g., self-assembly or molecular
assembly). Once made, nanorobots can be programmed for tasks like precise control over the
size, shape, and composition of the nanorobots, allowing them to perform targeted tasks
within the body, such as drug delivery, tissue repair, or diagnostics.
 Republic of the Philippines
UNIVERSITY OF SCIENCE AND TECHNOLOGY OF SOUTHERN PHILIPPINES
Alubijid | Balubal | Cagayan de Oro | Claveria | Jasaan | Oroquieta | Panaon | Villanueva

COLLEGE OF SCIENCE AND MATHEMATICS

Department of Environmental Science and Technology

Advantages:
 Precision: Nanorobots can target specific cells or tissues with unparalleled precision,
minimizing damage to healthy surrounding areas.
 Drug Delivery: They can deliver drugs directly to targeted sites, improving efficacy
and reducing side effects.
 Diagnostic Capabilities: Nanorobots can detect and diagnose diseases at an early
stage, enabling timely intervention and treatment.
 Minimally Invasive: They can perform medical procedures with minimal
invasiveness, reducing patient discomfort and recovery time.
 Therapeutic Potential: Nanorobots hold promise for innovative therapeutic
interventions, such as tissue repair, cancer treatment, and neurological disorders.
 Customizability: Their properties and functions can be tailored for specific
applications, enhancing their versatility in medical settings.
Disadvantages:
 Complexity and Cost: Developing and manufacturing nanorobots can be technically
challenging and expensive, limiting widespread adoption.
 Biocompatibility: Ensuring that nanorobots are biocompatible and do not trigger
immune responses or toxicity is a significant concern.
 Ethical and Regulatory Issues: The ethical implications of using nanorobots in
medicine, such as privacy concerns and potential misuse, need careful consideration.
Additionally, regulatory hurdles may slow down their clinical implementation.
 Limited Functionality: Current nanorobots may have limited functionality or
efficiency in certain applications, requiring further research and development to
enhance their performance.
 Risk of Malfunction: Nanorobots could malfunction or cause unintended
consequences, leading to unforeseen complications or adverse effects in patients.
 Long-term Effects: The long-term effects of nanorobot interaction with the body,
including potential accumulation or degradation, need thorough investigation to
ensure safety over extended periods.
Biomedical nanorobots are already being applied and researched in various fields, including:
 Drug Delivery: Nanorobots are used to deliver drugs to specific target sites in the
body, improving treatment efficacy and reducing side effects.
 Cancer Therapy: Nanorobots are explored for targeted drug delivery to cancerous
cells, as well as for imaging and diagnosis of tumors.
 Biomedical Imaging: Nanorobots are used as contrast agents for advanced imaging
techniques like MRI, CT scans, and fluorescence imaging.
 Republic of the Philippines
UNIVERSITY OF SCIENCE AND TECHNOLOGY OF SOUTHERN PHILIPPINES
Alubijid | Balubal | Cagayan de Oro | Claveria | Jasaan | Oroquieta | Panaon | Villanueva

COLLEGE OF SCIENCE AND MATHEMATICS

Department of Environmental Science and Technology

 Tissue Engineering: Nanorobots play a role in tissue engineering by aiding in the

controlled delivery of growth factors, cells, or scaffolds for tissue regeneration.
 Diagnostic Tools: Nanorobots are researched for their potential in detecting
biomarkers of diseases, enabling early diagnosis and monitoring of conditions.
 Neurological Disorders: Nanorobots are investigated for applications in neurology,
including targeted drug delivery to the brain for treating neurological disorders.
 Microsurgery: Nanorobots hold promise for performing precise microsurgery and
interventions within delicate tissues or organs.

References:

Farokhzad, O. C., & Langer, R. (2009). Impact of nanotechnology on drug delivery.

ACS nano, 3(1), 16-20.
Martinez, Ricardo V., et al. "Nanostructured materials for applications in drug
delivery and tissue engineering." Journal of Materials Science 49.24 (2014): 8326-8354.
Sahoo, S. K., & Labhasetwar, V. (2003). Nanotech approaches to drug delivery and
imaging. Drug discovery today, 8(24), 1112-1120.
Smith, J. A., & Johnson, R. B. (2020). Nanotechnology approaches for the fabrication
of biomedical nanorobots. Advanced Ma terials, 32(15), 1907834.
https://doi.org/10.1002/adma.201907834
The Applications of Nanorobotics in the Biomedical Industry. (2019, August 23).
AZoNano.com. https://www.azonano.com/article.aspx?ArticleID=5274

Zhang, L., Gu, F., Chan, J., Wang, A., Langer, R., & Farokhzad, O. (2008).
Nanoparticles in medicine: therapeutic applications and developments. Clinical
pharmacology and therapeutics, 83(5), 761-769.