edema of the skin & s/c tissue (in severe case) - in the next stage → scab formation or may be - necrosis or gangrene systemic reaction (if the affected area is - extensive) diffuse cellulites (spread of infection to s/c tissue) - : Treatment I/M or I/V injection of Avil → 1 amp/70 kg b.wt -1 )antihistaminic( I/M injection of Predef 2x → 10 cm / I.M -2 or Finadyne → 2 cm /45 kg b.wt / cattle / I.M cm / 45 kg b.wt/horse / I.M 1 → or Dexamethasone → 5-12 cm / I.M / cattle & horse local application of Zinc oxide oint. 15% as local emollient -3 )gm zinc oxid + Vaseline up to 100 gm 15( local application of Salicylic acid oint. 6% as local keratolytic-4 Salicylic acid 6 gm + Benzoic acid 3 gm + Vaseline up to 100( )gm in early (weeping stage) → local application of antiseptic -5 lotion as pot.permenganate sol. 1/1000 :N.B the 2 ointment applied alternative with each other within the same time in case of constipation → liquid paraffin -6 liter/ 100 kg b.wt/orally (as purgatives) 1 :N.B may use of a dusting powder ( mixture of 2 gm zinc oxid + 5 gm tannic acid + 20 gm starch) : I/M injection of antibiotic -7 may be use of local antibiotic ointment as * Terramycine or Garamycine or local anti-inflammatory ointment as Allergyl * or Betaderm or Betamethazone ointment or local antifungal ointment as Canastin * ointment :N.B the type of the ointment used differ acc. to type of the - cause & your diagnosis