Spontaneous posterior deviation of the tracheoesophageal septum or From some mechanical factor pushing the dorsal wall of the foregut anteriorly. In its most common form, The proximal part of the esophagus ends as a blind sac The distal part is connected to the trachea by a narrow canal just above the bifurcation Polyhydramnios Atresia of the esophagus prevents normal passage of amniotic fluid into the intestinal tract, Resulting in accumulation of excess fluid in the amniotic sac Stenosis esophageal the lumen of the esophagus may narrow may be caused by incomplete recanalization, vascular abnormalities or accidents that compromise blood flow. Congenital hiatal hernia the esophagus fails to lengthen sufficiently the stomach is pulled up into the esophageal hiatus through the diaphragm. Stomach Abnormalities: Pyloric stenosis occur When the circular and longitudinal musculature of the stomach in the region of the pylorus hypertrophies Pancreatic Abnormalities: Annular pancreas The right portion of the ventral bud migrates along its normal route The left migrates in the opposite direction. In this manner, the duodenum is surrounded by pancreatic tissue > duodenal stenosis. Body Wall Defects: Omphalocele involves Herniation of abdominal viscera through an enlarged umbilical ring. Viscera, which may include liver, small and large intestines, stomach, spleen, or gallbladder Can be diagnosed by ultrasound Gastroschisis Refers to a protrusion of abdominal contents through the body wall directly into the amniotic cavity. Occurs lateral to the umbilicus usually on the right Due to abnormal closure of the body wall around the connecting stalk Viscera are not covered by peritoneum or amnion Umbilical fistula or vitelline fistula The vitelline duct remains patent over its entire length, forming a direct communication between the umbilicus and the intestinal tract. Gut Rotation Defects: Left-sided colon Normally, the primary intestinal loop rotates 270 counter clockwise. However, rotation amounts to 90 only When this occurs, The colon and cecum are the first portions of the gut to return from the umbilical cord. They settle on the left side of the abdominal cavity Hindgut Abnormalities: Recto urethral and rectovaginal fistulas, Caused by abnormalities in formation of the cloaca or the urorectal septum. Recto anal fistulas and atresia Leave a narrow tube or fibrous remnant connected to the perineal surface Due to misexpression of genes during epithelial mesenchymal signaling
Congenital megacolon Hirschsprung disease
due to an absence of parasympathetic ganglia in the bowel wall