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SCI8 Q4 M2 Comparing Mitosis and Meiosis
SCI8 Q4 M2 Comparing Mitosis and Meiosis
Science
Quarter 4 –Module 2
Comparing Mitosis and Meiosis and the
Significance of Meiosis in Maintaining
the Chromosome Number
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What I Need to Know
This module was designed and written with you in mind to help you
understand the cell’s way of reproducing itself and the significance of meiosis. This
module is divided into two lessons, namely:
What I Know
Read each question carefully and encircle only the letter of the correct answer.
1. In what phase of the cell cycle do cells grow rapidly and perform many
metabolic processes?
A. Interphase C. Growth Phase 2
B. Growth Phase 1 D. Synthesis
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4. In order for an organism to grow and reproduce, its cell must undergo division.
Which of the following is TRUE about the significance of mitosis and meiosis?
A. Mitosis revitalizes damaged cells, while meiosis is for asexual reproduction.
B. Mitosis facilitates growth while meiosis takes part in the production of
gametes.
C. Mitosis maintains the chromosome number of an organism, while meiosis
is for sexual reproduction.
D. Mitosis repair and replace dead cells, while meiosis helps to produce more
cells during development.
7. Which of the following type of cells are NOT formed during meiosis?
A. Gametes C. Sex cells
B. Reproductive cells D. Somatic cells
8. If a chicken cell has 39 pairs of chromosomes, how would you describe the
cell?
A. It is a diploid somatic cell. C. It is a diploid sex cell.
B. It is a haploid somatic cell. D. It is a haploid sex cell.
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Lesson
Comparing Mitosis and
1 Meiosis
When you were in Grade 7 you learned that no matter how big or small an
organism is, their body is made up of cells. It is a fact therefore that all living
organisms are made up of cells and for that reason, cell is said to be the building
block of life.
What’s In
Are you aware that we have two sets of cells? These are somatic cells or body
cells that can be found in the different parts of our body except sex cells. The other
set of cells are the reproductive cells or gametes – sperm cells for males and egg
cells for females. Classify the following pictures of cells below as somatic cell or
reproductive cell by checking ( ) on the appropriate column.
1. epithelial cells
2. egg cell
3. cardiac cells
4. sperm cell
5. nerve cell
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What’s New
Activity 1: The Cell Cycle
Objectives:
1. Identify the phases of the cell cycle.
2. Describe the sequence of events that take place in each phase of cell cycle.
What you need:
Cell Cycle Diagram
Procedure:
1. Study the cell cycle diagram on Figure 1.
2. Use the diagram and the paragraph to answer the following guide questions
below.
A cell cycle is a series of events that take place in the life of a cell as it grows
and divides. It consists of two major phases: The Interphase, which is also known as
the preparatory or resting stage, and the Mitotic phase, the actual cell division.
During interphase, a cell grows, replicates its chromosomes, and prepares for cell
division. It is further subdivided into three subphases: 1. The G1 phase (first gap
phase), where the cell grows physically larger, copies organelles, and makes the
molecular building blocks it will need in later steps. 2. The S phase (synthesis phase),
where the cell synthesizes a complete copy of the DNA as well as the protein attached
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to them. 3. The G2 phase (second gap phase), where the cell grows more, makes
proteins and organelles, and prepares the cell for chromosomal separation. During
the Mitotic phase (M phase), the cell undergoes division of the nucleus and cytoplasm
to make two new identical daughter cells.
Guide Questions:
1. What is a Cell cycle? What are the two major phases of the Cell Cycle?
___________________________________________________________________________
___________________________________________________________________________
2. Differentiate Interphase and Mitotic phase.
___________________________________________________________________________
___________________________________________________________________________
3. What are the three subphases of interphase? Give their role in the Cell Cycle?
___________________________________________________________________________
___________________________________________________________________________
___________________________________________________________________________
4. Which do you think is the longest phase in the Cell Cycle? Why?
___________________________________________________________________________
___________________________________________________________________________
5. Which do you think is the most important event in the Cell Cycle? Justify your
answer.
___________________________________________________________________________
___________________________________________________________________________
What Is It
Mitosis is a process where a single parent cell divides into two identical
daughter cells. It is a type of cell division involving somatic cells (body cells). It
consists of four major phases namely: Prophase, Metaphase, Anaphase, and
Telophase.
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Metaphase Spindle fiber is fully developed
Centrosomes are at the opposite
(alignment of
poles
chromosomes)
The centromere of each sister
chromatid is attached to a spindle
fiber
Chromosomes line up at the
metaphase plate or equatorial plate.
What is Meiosis and the events that take place in each phase?
Meiosis is a process where a cell divides twice to produce four daughter cells
containing half the original amount of genetic information of the parent cell. These
cells are our reproductive cells (sex cells or gametes) – sperm cells in males while egg
cells in females. It involves two successive nuclear divisions. During the first meiotic
division (Meiosis I), homologous chromosomes separate, and on the second meiotic
division (Meiosis II), each chromosome separates into two chromatids.
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Leptotene: where chromosomes
start to condense.
Zygotene: synapsis (pairing of
Prophase I homologous chromosomes) occurs
to form tetrad (pairs of
chromosomes consisting of four
chromatids)
Pachytene: crossing over (the
exchange of genetic materials
between homologous chromosomes)
occurs forming a chiasma (the point
of contact of crossing over).
Diplotene: homologous
chromosomes begin to separate but
remain attached by chiasmata (sing.
chiasma)
Diakinesis: homologous
chromosomes continue to separate
and they are dispersed in the
nucleus.
The centrioles are now at the
opposite poles of the cell.
The spindle fibers from opposing
Metaphase I centrioles connect to centromeres
of bivalent (one pair of
chromosomes in a tetrad).
Bivalents line up at the metaphase
plate or equatorial plate
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Metaphase II Individual chromosomes line up at
the equator
Remember:
For an organism to grow and reproduce, cells must divide. Both mitosis and
meiosis are preceded by interphase, where the chromosomes in the nucleus are
replicated. The nucleus then divides, which is referred to as Karyokinesis.
Followed by a division of the cytoplasm called Cytokinesis.
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What’s More
Activity 2. Sudoku Time! Guess and Check
From the list of answers on the right, choose the term which best completes or
answers each statement on the left. Write the number of your answer in the proper
space on the box. If you got the correct answer for each box, the sum of the numbers
in each row, across, down, in the four corners, in the center boxes, and the diagonal
boxes will be the same. Write the sum of the numbers on the small box.
STATEMENT ANSWER
A. Type of cell where mitosis occurs. 0. Crossing over
B. A term used to describe a cell having half the 1. Interphase
number of chromosomes. 2. Metaphase
C. Division of the cytoplasm. 3. Sperm cells
D. The exchange of genetic materials between 4. Meiosis
homologous chromosomes 5. Chiasma
E. Subphase of prophase I in Meiosis where pairing 6. Karyokinesis
of homologous chromosomes take place. 7. Somatic cell
F. The resting stage of cell cycle. 8. S phase
G. A division of cell nucleus. 9. Cell cycle
H. A type of cell division that results in two identical 10.Haploid
daughter cells. 11.Mitosis
I. Alignment of chromosomes at the equatorial plate 12. Egg cells
is evident during this phase of Mitosis. 13.Zygotene
J. It refers to one pair of chromosomes in a tetrad. 14.Cytokinesis
K. A phase of cell cycle where DNA has been replicated. 15. Diploid
L. The point of contact of crossing over. 16.Bivalent
M. An ordered series of events involving cell growth
and cell division.
N. It produces four haploid daughter cells.
O. Male reproductive cells.
P. A cell with a complete set of chromosomes.
A. B. C. D.
E. F. G. H.
I. J. K. L.
M. N. O. P.
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What I Have Learned
3
importance of mitosis and
meiosis
2
differences of mitosis and
meiosis
1
common characteristic to
mitosis and meiosis
What I Can Do
Activity 4. Fit me in!
The letters at the bottom fit into the columns above to form the correct answer. Use
the statement as clues to identify the term in each set of blanks. Each letter can only
be used once. SHADE the letters as you used them. Number one answer is done for
you.
M E I O S I S
1. It occurs in the gamete-producing cell.
2. The longest phase in the cell cycle.
3. A type of nucleic acid that is being
synthesized during the S phase.
4. It is formed during synapsis.
5.It is responsible for cell growth and repair.
D C A L A D C I C A E E 6. A series of events that take place in the
T E E N L E E O H I I S life of a cell as it grows and divides.
N I R MI R P O L S
T T M T Y S S S
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Assessment
Match the term to its description by writing the letter of the correct answer before
each number.
A. Centromere B. Chromatid C. Cytokinesis
D. Diploid E. Haploid F. Karyokinesis
_____ 1. It refers to one of the two strands of a copied chromosome.
_____ 2. Serves as a link to a pair of sister chromatids.
_____ 3. A term used to describe a cell that contains one set of chromosomes.
_____ 4. It refers to cytoplasmic division.
_____ 5. It is used in describing a cell that contains two copies of each chromosome.
Additional Activities
Mitosis Meiosis
similarities
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Lesson
2 Significance of Meiosis
What’s In
What’s New
Activity 1: Word Hunting!
Directions: Choose the correct term from the word box below and write it on the
blanks to complete the content of the paragraph.
Meiosis is a process where a cell divides twice to produce four daughter cells
containing half the original amount of genetic information of the parent cell. The
process begins with a parent cell that is (1) _____________, meaning it has two copies
of each chromosome. It occurs in the reproductive organs and results in the
formation of (2) _____________, sperm cells in males and egg cells in females. The
entire process is divided into two, Meiosis I or first meiotic division in which the goal
is to separate (3) _____________ pairs and Meiosis II or second meiotic division which
goal is to separate sister chromatids just like in mitotic division. Therefore, the
process of meiosis results in the formation of (4) _____________ haploid daughter cells
that go on to develop into either sperm or egg cells. Each (5) _____________ is identical
to the mother cell in shape and size but different in terms of chromosome number.
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What Is It
What is Spermatogenesis?
Spermatogenesis is the process of formation of sperms. It occurs in the testes
of the male, specifically in the seminiferous tubules. Males start producing sperm
when they reach puberty, which is usually from 10-16 years old. They are produced
in large quantities about 200 million a day.
Meiosis I produce two haploid cells, known as secondary spermatocytes
Meiosis II produces four haploid cells, known as spermatids.
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What is Oogenesis?
Oogenesis is the production of an ovum. It differs from spermatogenesis in
that it begins in the fetus prior to birth. Primordial germ cells (which originate in the
yolk sac of the embryo) move to colonize the cortex of the primordial gonad and
replicate by mitosis to peak at approximately 7 million by mid-gestation (~20 weeks).
Cell death occurs after this peak to leave 2 million cells that begin meiosis I
before birth, these are known as primary oocytes. Therefore, a human female is born
with approximately 2 million primary oocytes arrested in meiosis, meaning they have
a finite supply of potential ova.
The primary oocytes are arranged in the gonads in clusters surrounded by
flattened epithelial cells (follicular cells) and these form primordial follicles. The
primary oocytes are arrested in the prophase stage of meiosis I.
During childhood, further atresia (cell death) occurs, leaving ~40,000 eggs at
puberty. Once puberty begins, a number of primary oocytes (15-20) begin to mature
each month, although only one of these reaches full maturation to become an oocyte.
Source: https://www.toppr.com/ask/question/sketch-and-label-phases-in-oogenesis/
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Figure 4. A comparative analysis of Spermatogenesis and Oogenesis
Source: http://www.old-ib.bioninja.com.au/higher-level/topic-11-human-health-and/114-reproduction.html
Significance of Meiosis
for the formation of sex cells or gamete that are essentials for sexual
reproduction
it allows genetic variation and variance among organisms
it allows assortment of chromosomes from parents
it maintains the normal number of chromosomes in sexually reproducing
organism
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What’s More
Activity 2: Analyze Me!
Analyze the following questions and fill in the blank with the correct answer.
1. How many sperms would form out of:
a. 4 primary spermatocytes? _______ c. 12 spermatids? _______________
b. 6 spermatogonia? _______________
2. If a dog has 78 number of chromosomes, how many chromosomes are there in its:
a. stomach cell? _______________ c. sperm cell? _______________
b. egg cell? _______________
What I Can Do
READ AND REFLECT: Read and understand the given information. Fill in the table
with the correct answer.
SPERMATOGENESIS VS OOGENESIS
Spermatogenesis takes place in the testis of mature and fertile males while
oogenesis takes place in the ovaries of mature and fertile females.
From one spermatogonium, four haploid sperms are formed during
spermatogenesis while from one oogonium one haploid ovum and a polar body are
formed during oogenesis.
Spermatid development takes place which later becomes a functional sperm
while ootid development does not take place during oogenesis. It develops only
after fertilization.
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Basis of comparison Spermatogenesis Oogenesis
Place where it occurs
Parent cell
Daughter cell
Number of gametes produced
Assessment
Write the corresponding answer on the space provided that shows relationship.
1. _______________: sex cells; diploid: somatic cells
2. male gametogonia: spermatogonia; female gametogonia: _______________
3. spermatogenesis: formation of sperms; _______________: formation of egg cells
4. _______________: female gonad; testis: male gonad
5. sperm cell: male reproductive cell; _______________: female reproductive cell
Additional Activities
EXPRESS YOURSELF
Part I. Reflect on the question and write your answer briefly. Please be guided by the
rubric below.
Reflection: ________________________________________________________________________
____________________________________________________________________________________
____________________________________________________________________________________
Part II. Make a research on the importance of variation in plant and animal breeding.
Write it on a short bond paper.
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Posttest
Read each question carefully and encircle only the letter of the correct answer.
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7. Which of the following differentiates synapsis from crossing over?
A. Synapsis occurs during prophase I while crossing over occurs during
metaphase I.
B. Synapsis is the splitting of two sister chromatids while crossing over is the
pairing of two homologous chromosomes.
C. Synapsis is the pairing of two homologous chromosomes while crossing
over is the exchange of the genetic material of paired chromosomes.
D. Synapsis is the pairing of two homologous chromosomes during mitosis
while crossing over is the exchange of the genetic material during meiosis.
8. Which of the following events take place during telophase of mitosis and
telophase II of meiosis?
A. Shortening of the spindle fiber.
B. Reformation of the nuclear membrane.
C. Alignment of chromosomes at the equatorial plate.
D. Movement of daughter chromosomes toward the poles.
10. Which of the following statements does NOT describe the significance of
meiosis?
A. Meiosis allows asexual reproduction.
B. Meiosis is responsible for the formation of gametes
C. Meiosis produces genetic variation by way of the process of recombination.
D. Meiosis ensures that all organisms produced contain the correct number of
chromosomes.
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References
Books:
Ocampo, Pia, May Chavez, Maria Helen Catalan, and Leticia Catris.. Science
Learner's Module. Pasig City: Department of Education. 2013
Internet Sources:
https://courses.lumenlearning.com/biology1/chapter/the-cell-cycle/
https://www2.le.ac.uk/projects/vgec/highereducation/topics/cellcycle-mitosis-
meiosis
https://www.yourgenome.org/facts/what-is-mitosis
https://www.philpoteducation.com/mod/book/view.php?id=790&chapterid=1053#/
https://blog.prepscholar.com/mitosis-vs-meiosis
https://microbenotes.com/differences-between-mitosis-and-meiosis/
https://byjus.com/biology/difference-between-spermatogenesis-and-oogenesis/
https://teachmephysiology.com/reproductive-system/embryology/gametogenesis/
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Lesson 1
What’s In
1. Somatic cell
2. Reproductive cell
3. Somatic cell
4. Reproductive cell
5. Somatic cell
What’s New
1. Cell cycle is a series of events
that take place in the life of a
cell as it grows and divides. Its
two major phases are
interphase and mitotic phase.
2. Interphase is the preparatory
or resting stage while mitotic
phase is the actual cell
division.
3. G1 phase – growth and normal
metabolic role
S phase – DNA replication
G2 phase – growth and
preparation for mitosis
4. Interphase because it allows
the cell to grow, replicate its
DNA, and make final
Mitosis
Also known as
preparations for cell division,
Meiosis
Also known as equational 5. Interphase because it is the
reduction Similarities division time when the cell grows and
division Involve one engages in diverse metabolic
Involve two cell division
start with activities. It decides if a cell
cell divisions Involved
one
Involved sex somatic cells should divide or not.
diploid
cells parent cell Daughter cells
Daughter cells are the same
preceded What I have Learned
are genetically by Produces two
diploid 3 importance of mitosis and meiosis
different interphase
Additional Activities
Produces four daughter cells Make new cells
haploid Mitosis is for cell growth and
daughter cells development
Meiosis is for production of
5. D
4. C gametes
3. E 2 differences of mitosis and meiosis
2. A Number of daughter cells
1.B produced
Assessment Chromosome numbers of
daughter cells
Cell Cycle 6. (Mitosis produces 2 diploid daughter
Mitosis 5. cells while meiosis produces 4 haploid
Tetrad 4. daughter cells)
DNA 3. 1 common characteristic to mitosis
Interphase 2. and meiosis
Meiosis 1. They both start with diploid
What I can Do. parent cell
Answer Key
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Lesson 2 Lesson 2
What I can Do What’s New
Spermatogenesis Oogenesis 1. diploid
Place where it occurs testis ovary 2. gametes
Parent cell spermatogonium oogonium 3. homologous
Daughter cell Sperm cell Egg cell/ovum 4. four
No. of gametes 4 1 matured ovum 5. daughter cell
produced and 3 polar What I have Learned
bodies
1. Spermatogenesis and oogenesis
2. Spermatogenesis occurs in the
testes of a male during puberty
Assessment
stage while oogenesis occurs in
the ovaries of a female prior to
1. haploid
2. oogonia birth.
3. oogenesis 3.
4. ovary Formation of sex cells that are
5. egg cell/ ovum essentials for sexual
reproduction
It allows genetic variation
It maintains normal
chromosome number
Development Team of the Module
Writer: Imelda N. Del Rosario
Management Team:
Sheryll T. Gayola
Assistant Schools Division Superintendent
OIC, Office of the Schools Division Superintendent
Elisa O. Cerveza
Chief, CID
OIC, Office of the Assistant Schools Division Superintendent
Jessica S. Mateo
EPS-Science
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