Scribd Logo
Upload

Welcome to Scribd!

  • Tooling of Oral Solid Dosage Form

    Uploaded by

    dhar09mesh
    87 views3 pages
    Tablets are solid oral dosage forms containing drug substances with or without excipients. They are manufactured by compression or molding using punches and dies. Different types of punches are used depending on the tablet shape and features. Procurement of tooling requires providing specifications such as the number of sets, material of construction, engraving details, and special requirements to the approved supplier. The supplier then provides a drawing or sample for approval before manufacturing. The main types of tooling are B, D, BB, and DB which determine the maximum tablet size that can be produced.

    Original Description:

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Tablets are solid oral dosage forms containing drug substances with or without excipients. They are manufactured by compression or molding using punches and dies. Different types of punches are used depending on the tablet shape and features. Procurement of tooling requires providing specifications such as the number of sets, material of construction, engraving details, and special requirements to the approved supplier. The supplier then provides a drawing or sample for approval before manufacturing. The main types of tooling are B, D, BB, and DB which determine the maximum tablet size that can be produced.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    87 views3 pages

    Tooling of Oral Solid Dosage Form

    Uploaded by

    dhar09mesh
    Tablets are solid oral dosage forms containing drug substances with or without excipients. They are manufactured by compression or molding using punches and dies. Different types of punches are used depending on the tablet shape and features. Procurement of tooling requires providing specifications such as the number of sets, material of construction, engraving details, and special requirements to the approved supplier. The supplier then provides a drawing or sample for approval before manufacturing. The main types of tooling are B, D, BB, and DB which determine the maximum tablet size that can be produced.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 3

    Tooling of Oral Solid Dosage Form (Tablet)

    Drug substances are frequently administered orally by means of solid dosage forms such as Tablets and Capsules. n Definition of Tablets Tablets can be defined as Solid Pharmaceutical Dosage form containing drug substances with or without suitable diluents and prepare either by compression or molding methods. There are various types of Tablets and abbreviations used in referring them are as follows. 1. Compressed Tablets (CT) 2. Sugar-Coated Tablets (SCT) 3. Film-Coated Tablets (FCT) 4. Enteric-Coated Tablets (ECT) 5. Multiple Compressed tablets (MCT) Layered Tablets Press-Coated Tablets. 6. Controlled Release tablets. 7. Tablets for Solution. 8. Effervescent tablets. 9. Compressed Suppositories or inserts. 10. Buccal and Sublingual Tablets. 11. Vaginal tablets. 12. Lozenges. 13. Implants. Types of Tablets Tablet Tooling For this purpose different types of punches are used: Flat- faced bevel- edged. Shallow concave (Round/ Capsule shaped) Standard concave (Round/ Capsule shaped) Deep concave (Round/ Capsule shaped) Extra deep. Modified ball Compressed Tablets: These tablets are formed by compression and contain no special coating. They are made from powdered, crystalline or granular material, alone or in combination with binders, disintegrants, lubricants, diluents and in many cases, colorants. For different types of tablets as per their usage, market requirement, elegancy etc.

    The basic mechanical unit in all tablet-compression equipment includes a lower punch which fits into a die from the bottom and an upper punch, having a head of the same shape and dimensions, which enters the die cavity from the top after tableting material fills the die cavity. PROCUREMENT OF TOOLINGS While ordering any punch set (From Approved Supplier only), following things should be covered: 1. Drawing for upper/lower punch / die, by the manufacturer as per the specifications given or as per sample punch set. 1. Following details should be given with the purchase order: Total number of set required Type of punch set eg. D/B/BB etc. MOC to be used (HCHC/OHNS) HCHC: High Carbon High Chromium OHNS: Oil Hardened non shrinking Steel Engraving details; Sr. no., Mfr name, Date of Mfg., Punch size in mm. Special requirements like: Concavity, embossing, chrome plating etc. Tablet Tooling There are following types of Tooling available: B -Tooling D - Tooling BB -Tooling 'DB - Tooling Approval of drawing /sample punch set from department head and unit head. The following are the different types of tooling, their dimensions and maximum possible tablet sizes :

    You might also like