Professional Documents
Culture Documents
10Y Venners C-R
10Y Venners C-R
⁎
Thais Mazzetti a, , Kauê Collares b, Bruna Rodolfo c,
Paullo Antônio da Rosa Rodolpho c, Françoise Hélène van de Sande a,
Maximiliano Sérgio Cenci a,d
a
Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Brazil
b
Postgraduate Program in Dentistry, Dental School, University of Passo Fundo, Brazil
c
Private Dental Practitioner, Caxias do Sul, Brazil
d
Radboudumc University Medical Center, Department of Dentistry, Nijmegen, Netherlands
ar ti cl e i n f o ab stra ct
Article history: Objectives: This 10-year practice-based study aimed to compare survival and success of
Received 30 September 2021 direct resin composite and ceramic veneers placed in a private dental practice, between
Received in revised form 26 January January 2008 and March 2014.
2022 Methods: Data were retrieved from a clinical practice’s records and were anonymized typed
Accepted 15 March 2022 into electronic files. All veneer information was recorded, including previous restorations,
repairs or failures, materials used, dates, patient, and age.
Keywords: Results: We analyzed 1459 veneer restorations, of which 1043 (71.5%) were direct compo
Risk factors site, and 416 (28.5%) were ceramic, placed in 341 patients. The mean patients’ age was 47.8
Electronic dental records years, and the mean number of restorations per patient was 4.3 restorations. During all
Dental materials follow-up, 957 (65.6%) veneers were successful without any repair, 252 (17.3%) were re
Dental restoration failure paired and still in place, and 250 (17.1%) had a failure that resulted in replacement.
Dental restoration repair Replacements were usually carried out with the same material placed at first. Considering
Survival analysis success analysis, annual failure rates (AFR) for veneers in 5 and 10 years were 9.1% and 10%
Survival rate for direct composite and 2.9% and 2.8% for ceramic, respectively. Survival analysis showed
AFR of 3.9% and 4.1% for composite and 1.4% and 1.2% for ceramic at the same periods. Cox
regression was made for both success and survival outcomes. Composite veneers pre
sented a higher risk of failure than ceramic veneers with higher hazard ratios for survival
(HR) [HR 4.00 (2.74–5.83)] and success [HR 5.16 (2.65–10.04)].
Significance: Ceramic veneers had superior longevity than direct composite veneers in both
success and survival analysis.
© 2022 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.
⁎
Correspondence to: Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, 457 Gonçalves Chaves St,
Pelotas, RS 96015-560, Brazil.
E-mail addresses: thais.mazzetti@ufpel.edu.br (T. Mazzetti), maximiliano.cenci@ufpel.edu.br,
max.cenci@radboudumc.nl (M.S. Cenci).
https://doi.org/10.1016/j.dental.2022.03.007
0109-5641/© 2022 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.
dental materials 38 (2022) 898–906 899
2.1. Experimental design, inclusion criteria, and data 2.3. Outcome measures and definitions
selection
Success was defined as a restoration without any interven
This practice-based study evaluated data collection of direct tion from placement until the last appointment when it was
and indirect veneers placed by an expert clinician on a pri considered censored data [23]. In contrast, survival was de
vate clinic between Jan 2008 and March 2014 in Southern scribed as a still-functioning restoration and was at least
Brazil. This study is reported following the RECORD state partially in place during the follow-up time, even with repairs
ment (Reporting of Studies Conducted Using Observational [23]. Procedures such as finishing and polishing were not
Routinely Collected Health Data) [21], an extension of considered interventions. For the category repair, the same
Strengthening the Reporting of Observational Studies in criteria were used for both resin composite and ceramic
900 dental materials 38 (2022) 898–906
veneers. Recementation of the same veneer was considered Bayswater, VIC, Australia) between 2008 and 2012, and from
repair. Chippings or small fractures of the original veneer 2013, Valo 1000 mW/cm² (Standard mode) (Ultradent, South
(resin composite or ceramic) were considered as repair, and Jordan, UT, USA), both for 20 s for each tooth face. Materials’
treated with resin composite. Also, new direct restorations, application followed manufacturers’ instructions. After re
such as Class III, IV, and V, which did not cover all dental storation or repair placement, finishing and polishing proce
surfaces previously restored with the assessed veneer, were dures were carried out using fine multi-laminated drills (KG
considered as repair. Failures were defined as any entirely Sorensen, Barueri, SP, Brazil) and FlexiDisc and FlexiBuff
replaced veneer restorations. The last check-up visit dates discs (Cosmedent Inc, Chicago, IL, USA) with aluminum oxide
were recorded and deemed censored for the restorations' paste (Enamelize; Cosmedent). FlexiDisc and FlexiBuff discs
success and survival analyses. Annual Failure Rates (AFR) and abrasive strips (3 M ESPE, St. Paul, MN, USA) were used in
and cumulative survival rates were calculated for both sur proximal sites.
vival and success.
2.4.2. Indirect ceramic veneers
2.4. Clinical procedures Conservative teeth preparations were carried out for all-
ceramic veneers whenever possible, with a 1 mm preparation
All restorations and reinterventions were carried out by the at 45° at the incisal edge, and a supragingival margin when
same clinician, specialist, and expert on aesthetic dental re ever possible. The preparation extension was variable de
storations. Restorations were placed for several reasons, pending on factors related to the dental substrate, such as
mainly to improve the teeth' aesthetic, including correcting color and presence and extension of restorations, dental
the shape and/ or color and/or correcting fractures, among planning, and waxing. All restorations were manufactured in
others. For all veneer restorations, teeth with pre-existing the same dental laboratory by the same technician. Pressable
restorations placed by the same clinician were maintained. lithium-disilicate glass-ceramic was used for all veneer re
When old restorations were present and placed by another storations. Enamel and dentin were acid conditioned with
dentist, the adopted protocol removed the old restoration 37% phosphoric acid in all teeth, and the adhesive was ap
before the new veneer's placement. In almost all the cases, plied according to the manufacturer’s instructions. Ceramic
the clinical procedures were carried out under a rubber dam pieces were cleaned with alcohol, etched with 10% hydro
isolation, for both ceramic and resin composite veneers. fluoric and 37% phosphoric acid, and adhesive and silane
During the check-up appointments, the same clinician were applied. The adhesives used were the same from resin
observed intervention needs through clinical and radio composite veneers, Adper Single Bond 2 and Single Bond
graphical exams. Patients' aesthetical requirements could Universal, the cement of first choice was Variolink Veneer
also be a reason for repairs or replacements. For example, (Ivoclar Vivadent Schaan, Liechtenstein), and the silane was
correction of minor fractures or chipping, slight color differ Monobond N (Ivoclar Vivadent Schaan, Liechtenstein). The
ences, small anatomical corrections, caries, and debonding of light-curing units used were the same from direct resin
indirect restorations were treated as repairs. composite veneers, Radii and Valo, however the time was
For all veneers placed, the dentist recommended a return 40 s for each tooth face.
for evaluation every six months. In exceptional cases, where In the case of debonding, before a recementation, the
the patient needed to improve hygiene skills, the dentist re tooth surface was cleaned, and all remaining cement was
commended return every three months. removed with sodium bicarbonate jet and air-abraded using
50 µm aluminum oxide particles (ERC Microetcher; Danville
2.4.1. Direct resin composite veneers Engineering, San Ramon, CA, USA). After that, cementation
Most of these restorations did not require any dental pre was performed as already described. In the case of chippings,
paration on the sound teeth. Enamel was acid conditioned those were treated with resin composite repairs after air
with 37% phosphoric acid, and an adhesive was applied in all abrasion and silane application, followed with the use of the
the tooth surface. The clinician used mainly a conventional same adhesives and composites described. Extensive frac
two-step-etch-and-rinse adhesive (Adper Single Bond 2–3 M tures were treated with the replacement of the veneer.
ESPE, St. Paul, MN, USA) between 2008 and 2012, and a uni
versal adhesive (Single Bond Universal - 3 M ESPE, St. Paul, 2.5. Data analysis
MN, USA) between 2012 and 2014. The composite materials
most used during the period were a micro-hybrid (4 Seasons Statistical analyses were performed with STATA 14 software
Ivoclar Vivadent, Schaan, Liechtenstein) between 2008 and package (StataCorp LP) and SPSS v.23.0 (IBM Corp.)
2011 and a nano-hybrid (IPS Empress Direct, Ivoclar Vivadent, Descriptive analysis was used to summarize the data and
Schaan, Liechtenstein) composite between 2011 and 2014. report frequency distributions of restorations by independent
Repairs of resin composite restorations usually consisted variables. Survival and Success Kaplan-Meier graphs were
of a shallow preparation of the vestibular surface, surface generated to present curves for ceramic and composite ve
cleaning with sodium bicarbonate jet and air-abrasion using neers up to 11 years. AFRs were calculated from life tables
50 µm aluminum oxide particles (ERC Microetcher; Danville according to the formula (1 – y)² z = (1 – x), in which y ex
Engineering, San Ramon, CA, USA), acid conditioning with presses the mean AFR and x, the total failure rate at z years.
37% phosphoric acid, adhesive application, followed by the The evaluation of associated factors to failures considering
addition of a new increment of the composite. The light- success or survival was carried out by multivariate Cox’s re
curing units used were Radii Plus 800 mW/cm² (SDI, gression with shared frailty (patient) was used (α = 0.05).
dental materials 38 (2022) 898–906 901
Fig. 1 – Flow chart with the total of placed dental veneers and excluded with reasons.
Hazard ratios (HRs) with 95% confidence intervals (CIs) were 825 (79.1%) restorations survived, and the mean observation
determined for all variables included on Cox-Regression (pa time was 5.6 years (SD, 3.7). For ceramic veneers, 384 (92.3%)
tient’s sex and age, type of tooth, jaw, and materials). restorations survived, with the mean observation time being
6.6 years (SD, 4.0). Thus, the cumulative survival of the ve
neers in 10 years was 66% to composite and 89% to ceramic
3. Results
veneers (Appendix Table A.3). The Cox regression analysis
suggested an increased risk in the survival in the factors sex,
One thousand nine hundred and seventy veneer restorations
jaw, and material (Table 2). According to the material, the
placed during the inclusion period were screened. Of these,
survival graphs with the associated factors are available in
511 restorations were excluded (Fig. 1). A total of 341 patients
Fig. 2, such as the AFR of veneers.
and 1459 veneer restorations were included in the study.
From these, 1043 (71.5%) were direct composite and 416
(28.5%) ceramic. Patients’ age ranged from 18 to 83 years old 3.3. Failure
(mean, 47.8 years), and most of them were female (71.3%).
The number of restorations per patient ranged from 1 to 22 The number of failed restorations that were replaced was 250
(mean, 4.3). Table 1 shows the distribution of the sample by (17.1%), and they were replaced by new composite veneers
veneer type. The variable dental vitality was not included in (70.0%), ceramic veneers (27.6%), crowns (2.0%), and one im
the analysis since only 15.1% of the restored teeth had this plant (0.4%). Fig. 3 shows the distribution of replacement
data available. Not all clinical records had information about procedures according to the original material used in the
brands of materials used (Appendix Table A.1). The list of the veneer. Forty-two (16.8%) replaced restorations that had a
materials used and the characteristics are available in previous repair before the failure, while 208 (83.2%) were re
Appendix Table A.2. placed without any prior repair. The failure events for com
posite veneers were 218 (20.9%), and 32 (7.7%) in ceramic.
3.1. Success
4. Discussion
Nine hundred and fifty-seven (65.6%) veneer restorations did
not receive any repair before the censored data. The number This study presents the first long-term clinical evaluation
of successful composite veneers was 610 (48.5%), and ceramic comparing ceramic and direct composite veneers to the best
was 347 (83.4%), with the mean observation time was 4.9 (SD, of our knowledge. This study's results are in accordance with
3.7) and 6.3 years (SD, 4.0), respectively. Thus, composite and the existing literature, with ceramic veneers presenting a
ceramic veneers had 35% and 75% cumulative success rates superior performance compared to resin composite.
in 10 years, respectively (Appendix Table A.3). The Cox re Therefore, the study hypothesis was accepted.
gression analysis identified the factors associated with suc Gresnigt showed in a 10-year split-mouth randomized
cess (Table 2): tooth type, jaw, and restoration material. Fig. 2 clinical trial comparing indirect composite veneers and
shows the Kaplan-Meier curves of these factors and the AFR ceramic survival rates favoring ceramic veneers [10]. Another
of ceramic and composite veneers. 10-year study, with a retrospective design, evaluating
ceramic veneers on a general dental service in England, re
3.2. Survival veals that 53% of 2562 placed ceramic veneer restorations
survived without re-intervention [24]. A prospective clinical
Considering all veneers, 1209 (82.9%) were still in place even trial expressed success of 92% at 5 years and 64% at 10 years
when a repair was needed. In the composite veneers group, [25]. However, other studies show higher survival rates for
902 dental materials 38 (2022) 898–906
Table 1 – Distribution of composite and ceramic veneers (n = 1459) by patients and restorations characteristics.
Resin composite Ceramic Total
n = 1043 n = 416 n = 1459
n % n % n %
Age, years
18–30 117 11.2 34 8.2 151 10.4
31–45 240 23.0 115 27.6 355 24.5
46–64 634 60.8 255 61.3 889 61.4
≥ 65 52 5.0 12 2.9 64 4.4
Sex
Female 799 76.6 274 65.9 1073 74.1
Male 244 23.4 142 34.1 386 26.6
Tooth type
Central incisor 417 40.0 175 42.1 592 40.9
Lateral incisor 372 35.7 130 31.3 502 34.6
Canine 252 24.2 111 26.7 365 25.2
Jaw
Upper 884 84.8 372 89.4 1256 86.7
Lower 159 15.2 44 10.6 203 14.0
Substrate
Tooth 590 56.6 225 54.1 815 56.2
Partially composite 123 11.8 61 14.7 184 12.7
Total composite 322 30.9 118 28.4 440 30.4
Ceramic 8 0.8 12 2.9 20 1.4
Year of placement
2008 124 11.9 16 3.8 140 9.7
2009 88 8.4 92 22.1 180 12.4
2010 183 17.5 81 19.5 264 18.2
2011 191 18.3 66 15.9 257 17.7
2012 204 19.6 95 22.8 299 20.6
2013 227 21.8 50 12.0 277 19.1
2014a 26 2.5 16 3.8 42 2.9
a
Data collected until March 2014
Table 2 – Cox regression analyses on factors related to ceramic and direct composite veneers failures (n = 1433).
Success Survival
HR (95% CI) p-value HR (95% CI) p-value
Patient-related variables
Age (Continuous variable) 1.00 (0.98–1.01) 0.580 1.01 (0.98–1.04) 0.530
Sex (Ref = Female)
Male 1.31 (0.90–1.90) 0.162 2.31 (1.08–4.92) 0.030
Tooth related variables
Tooth (Ref = Lateral incisor)
Central Incisor 1.49 (1.20–1.86) < 0.001 1.23 (0.89–1.70) 0.201
Canine 0.87 (0.66–1.13) 0.288 0.75 (0.51–1.11) 0.146
Jaw (Ref = Lower)
Upper 1.90 (1.29–2.80) 0.001 2.31 (1.23–4.32) 0.009
Material (Ref = Ceramic)
Resin composite 4.00 (2.74–5.83) < 0.001 5.16 (2.65–10.04) < 0.001
Fig. 2 – Kaplan-Meier graphs showing for success tooth type (a), jaw (c) and restorations material (e), and, for survival patient
sex (b), jaw (d), and restoration material (f).
904 dental materials 38 (2022) 898–906
35
30
25
20
15
10
0
RC C RC C RC C RC C RC C RC C RC C RC C RC C RC C RC C RC C
0 1 2 3 4 5 6 7 8 9 10 11
Year after the procedure
Fig. 3 – Distribution of replacement procedures after the failure of resin composite (RC) and ceramic (C) veneers by year after
placement of the veneer.
ceramic veneers, up to 95% at 10 years and up to 87% in a 20- composites, this was mainly associated with the color and
year evaluation [14,15]. A systematic review of non-felds translucence of the old material. Furthermore, the present
pathic ceramic veneers indicated a cumulative survival of study data were collected in a referral practice for aesthetic
ceramic veneers over 90% and ranging between 66% and 94% restorations. Therefore, all patients had high demands for
(95% CI: 55–99%) for 10 years [26]. Variations between survival their teeth, which probably impacted the number of re
rates should be interpreted with caution due to different interventions observed. Besides, the procedures made after
criteria of failure that could be adopted by the authors [26]. failure indicate that most replacements were new veneers
Unfortunately, data from direct veneers are scarce com (97.6%), while more invasive procedures such as crown and
pared to ceramic veneers restorations. An interim evaluation implant represented only 2.4% of the new interventions. This
of direct, indirect composite veneers and ceramic showed a also means that very few catastrophic failures demanding
superiority of survival favoring ceramic veneers at a 2.5-year tooth extraction were observed, corroborating that treatment
follow-up [20]. However, these authors did not publish a with veneers may be considered safe for the patient.
longer evaluation, similar to most studies with direct ve The main limitation of this study concerns the absence of
neers, which are clinical cases with short follow-up periods. reasons for failure, since it was not possible to determine
In a retrospective clinical evaluation, Coelho-de-Souza de whether the failures occurred due to fractures and chippings,
monstrated a survival rate of 80% at 3.5 years for direct ve or simply because the patients desired to improve aesthetic
neers placed by postgraduate students [11], which could aspects, such as changing color or form of the veneers.
explain the drop in survival compared to our study, where an Although these aspects may be related to both materials, it
experienced dentist placed all the restorations. Conversely, a can overestimate the failures of resin composite veneers,
4-year evaluation of direct and indirect composite veneers, where patients may choose to replace composite with
direct veneers demonstrated the survival of 87.5% (AFR = ceramic veneers for a variety of reasons, such as being more
3.2%) [6]. In our knowledge, only one study, conducted at the sophisticated or more aesthetically appealing material.
same clinical practice, presented survival rates of a 10-year Another limitation of this study is the absence of information
evaluation of direct composite veneers, and it had a cumu due to a lack of data on dental records, as tooth vitality,
lative survival of 85% (AFR = 3.2%) at 5 years and 52% (AFR = which is an essential factor to increase failure of restorations
6.3%) at 10 years, and success of 74% (AFR = 5.8%) and 38% [11,20], and this variable was not analyzed due to lack of data.
(AFR = 9.2%) respectively [12]. Despite the similar results Data about dental substrate was also not used in the analysis
found between the two studies, some differences could be because it was collected from dental records of previous re
explained by the different years of data collection of the first storations of the patients. So, it was impossible to know for
study, 1994–2009, and the minimum follow-up time of 4 sure about the presence or absence of old restorations for all
years. patients. Only a single operator and the patient observed the
Even though this study does not explore the reasons for failures, which could affect the number of repairs or re
failure, because this information was not available in most placements.
clinical records, it is recognized that failure in anterior teeth Also, whereas most of the patients return to the dental
may occur mainly due to aesthetical requirements [7,27,28]. clinic frequently, as the dental practice from which these
Mostly, veneers with both materials were replaced due to data were retrieved is a referral practice for aesthetic den
fracture or according to the patient’s demands for an im tistry, some patients only go seeking a qualified specialist for
proved apparency of their anterior teeth. In the case of resin the aesthetic procedure, represented by the placement of
dental materials 38 (2022) 898–906 905
these veneers, and did not attend annually for follow-ups. Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES
Therefore, we considered these patients’ veneers as censored – Finance Code 001) for the financial support through scho
data to minimize bias in the analysis. It is also important to larship. MSC acknowledges to UFPel, Coordenação de
call the attention that some patients can choose one treat Aperfeiçoamento de Pessoal de Nível Superior (CAPES -
ment for many reasons. For example, a patient could opt for Finance Code 001), Conselho Nacional de Desenvolvimento
direct composite veneers, mainly for cost-related issues, and Científico e Tecnológico (CNPq) and Brazilian Ministry of
exchange all restorations for ceramic veneers a few years Health for partial financial support. All the authors of this
later. Besides, despite direct veneers' lower survival and study have no conflicts of interest to declare.
success than ceramic, this does not contraindicate direct
composite veneers' placement. Direct veneers represent a
procedure with lower biological and monetary costs and high
Appendix A. Supporting information
survival rates over the years. Well-informed patients should
Supplementary data associated with this article can be found
evaluate the best treatment option for their case with their
in the online version at doi:10.1016/j.dental.2022.03.007.
clinicians, considering the available evidence.
Regardless of this study's limitations, it brings a more
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