DETECTOR NOISE and DRIFT

A C Q U I S I TI O N I N F O R M A TI O N

System Name: BSM_SM_elPDA_TQD Acquired By: sqte

Project Name: SQT_E_BSM_SM_TQD_PDA_data Column serial Number:
Sample Set Method: 100 UV Noise SSM Sample Kit 1 Expiration Date:
Processing Method UV Noise PM Sample Kit 1 Lot Number:
Report Method Name: UV Noise RM Build Version: Empower 2 Software Build 2154 SPs
User Name: System Sample Set Id: 3301 Result Set Id: 3451
Sample Set Name: UV Noise SSM Sample Set Start Date: 1/5/2011 8:46:55 AM EST

In the Noise and Drift qualification, mobile phase (90% Water : 10% Acetonitrile) is pumped at 0.6 mL/min.
A blank chromatogram at 254 nm is collected at 3.6 nm resolution, 2 points per second and a 1 second
time constant for 15 minutes.

The average peak to peak noise is calculated based on a 30 second noise interval from 3 to 15 minutes.
The average peak to peak noise in microAU is reported.
The qualification passes if the Noise is < or = 80 microAU.

Detector drift is calculated from 3 to 15 minutes.

Drift is reported in mAU/Hr.
The qualification passes if drift is less than 10 mAU/Hr.

Noise Result Table

Average Peak to Peak

Noise Specification Noise Pass Fail
Noise (uAU)
1 < or = 80uAU 15 PASS

Drift Result

Drift Drift Drift

Specification (mAU/Hr) Pass/Fail
1 < or = 10.0 mAU/Hr 0.0 PASS

Printed 8:34:35 PM US/Eastern 4/26/2011 Page: 1 of 3

 DETECTOR NOISE and DRIFT
A C Q U I S I TI O N I N F O R M A TI O N

System Name: BSM_SM_elPDA_TQD Acquired By: sqte

Project Name: SQT_E_BSM_SM_TQD_PDA_data Column serial Number:
Sample Set Method: 100 UV Noise SSM Sample Kit 1 Expiration Date:
Processing Method UV Noise PM Sample Kit 1 Lot Number:
Report Method Name: UV Noise RM Build Version: Empower 2 Software Build 2154 SPs
User Name: System Sample Set Id: 3301 Result Set Id: 3451
Sample Set Name: UV Noise SSM Sample Set Start Date: 1/5/2011 8:46:55 AM EST

Printed 8:34:35 PM US/Eastern 4/26/2011 Page: 2 of 3

 DETECTOR NOISE and DRIFT
A C Q U I S I TI O N I N F O R M A TI O N

System Name: BSM_SM_elPDA_TQD Acquired By: sqte

Project Name: SQT_E_BSM_SM_TQD_PDA_data Column serial Number:
Sample Set Method: 100 UV Noise SSM Sample Kit 1 Expiration Date:
Processing Method UV Noise PM Sample Kit 1 Lot Number:
Report Method Name: UV Noise RM Build Version: Empower 2 Software Build 2154 SPs
User Name: System Sample Set Id: 3301 Result Set Id: 3451
Sample Set Name: UV Noise SSM Sample Set Start Date: 1/5/2011 8:46:55 AM EST

Average Peak-to-Peak Noise (uAU): 15 Sampling Rate: 2.00 per sec

Drift (mAU/Hr) 0.0 Processing Method: UV Noise PM

PDA 254.0 nm

Noise Chromatogram

0.00004

0.00003

0.00002
AU

0.00001

0.00000

-0.00001

3.00 4.00 5.00 6.00 7.00 8.00 9.00 10.00 11.00 12.00 13.00 14.00 15.00
Minutes
Channel Description PDA Spectrum (210-400)nm; Processed Channel Descr. PDA 254.0 nm

Printed 8:34:35 PM US/Eastern 4/26/2011 Page: 3 of 3