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Drug Study
Drug Study
Drug Study
GENERIC NAME Prescribed dosage Piperacillin: Binds to Treatment of Hypersensitive to drug CNS: headache, Assess patient for
bacterial cell wall moderate to severe and other pencillins, insomnia, fever, seizures, infection at
Piperacillin + 424 mg IVTT drip q6hrs bacterial infections, cephalosporins or beta- agitation, anxiety, beginning of and
membrane, causing cell
Tazobactam including lactamase inhibitors dizziness, pain during therapy.
Recommended dosage death. Spectrum is
community Obtain a history
extended compared with acquired/nosocomial CV: Arrhythmia, chest before initiating
4.5 gm q6h IV other penicillins. pain, edema, HTN,
pneumonia. therapy to determine
ROUTE: Tazobactam: Inhibits tachycardia previous use of and
BRAND NAME beta- lactamase, an reactions to penicillin
IV, IM GI: diarrhea, or cephalosporins.
enzyme that can destroy constipation, nausea,
Zosyn penicillins Obtain specimens for
abdominal pain, culture and
dyspepsia, vomiting sensitivity prior to
Respiratory: Dyspnea initiating therapy.
CLASSIFICATION
Observe patient for
Pharmacological: Hematologic: Anemia, signs and symptoms
Extended-spectrum thrombocytopenia of anaphylaxis.
penicillins – beta – Discontinue the drug
lactamase inhibitors Skin: Pruritus, rash and notify physician
immediately if these
Other: Anaphylaxis, occur. Keep
Therapeutic: Antibiotic
hypersensitivity epinephrine, and
reactions, inflammation, resuscitation
phlebitis at IV site. equipment close by
in the event of an
anaphylactic
reaction.
Monitor bowel
function. Diarrhea,
abdominal cramping,
fever, and bloody
stools should be
reported to physician
promptly as a sign of
CDAD.
Assess for skin
reactions.Monitor
patient with mild to
moderate rash for
progression.
If rash becomes
severe or systemic
symptoms occur,
discontinue
piperacillin/tazobacta
m.
DRUG STUDY
After: