Sankalp

PARIVARTAN

Series

Principle of inheritance
and Variation

By: Tarun Sir

Sankalp
 Sankalp
1. Mark the incorrectly matched.

(1) Hybridization Experiment - Mondel

(2) Pure Line - Homozygous

(3) F1 generation - Hybrid

(4) F2 generation - Three phonotype in monohybrid cross

 Sankalp
2. Mark the Dominant trait Selected By Mandel

(1) Dwarf

(2) Terminal Flower

(3) Green seed

(4) Yellow seed

 Sankalp
3. Which is Recessive trait

(1) Miniature wing in drosophila

(2) Person with Myotonic dystrophy

(3l Red eye colour in drosophila

(4) Brown Body in Drosophila

 Sankalp
4. S-I- Mendel use Statistical Analysis and Mathematical logic
S-I- In F1 generation only one Phonotype

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
5. Mark the incorrect:-

(1) Phenotype is not affected By Environment

(2) Genotype is Genetic make up of Organism

(3) Dihybrid means two character

(4) Monohybrid cross means cross between two Pure parent with Single Character.
 Sankalp
6. S-I- In monohybrid cross By Mendel, F1 Generation Resemble Any one of
the parent
S-II- In Monohybrid cross, F2 Generation haue progeny Similar to Both
parent

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
7. S-I- Test cross help to find Phenotype of unknown Ggenotype
S-II- Law of segregation is valid for both monohybrid and Dihybrid cross

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
8. Mark the incorrect.

(1) Co-dominence ABO Blood Groups

(2) Thallesimia - Autosomal Recessing

(3) Sickle cell anaemia – Autosomal Recessive

(4) Colour Blindness – Y-linked

 Sankalp
9. Chromosomal theory of inheritance means

(1) Gene located on chromosome

(2) Chromosome located on

(3) Only One Gene located on chromosome

(4) none of the Above

 Sankalp
10. T..H Morgan worked on Drosophila as it is

(1) Insect

(2) Diploid

(3) Chromosomes are Diploid

(4) Small size complete life cycle in two week

 Sankalp
11. S-I- Linkage discovered by T.H. Morgan
S-II- Linkage is directly proportional to Rocombinant

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
12. S-I- Sturtevant was student of Morgan
S-II- Recombination Frequency is directly proportional to distance b/w
linked gene

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
13. XX-XY Sex determination is present in

(1) Only in Mammal

(2) all Insect

(3) Some Insect

(4) Bird
 Sankalp
14. Mark the correct

(1) Bird - male Heterogametic

(2) Drosophila -Male produce two type of gametes

(3) Point Mutation - Sickle cell Anaemia

(4) Linkage map - Morgan

 Sankalp
15. S-I- Test cross Result is phenotype is equal to genotype
S-II- Both allele completely express is co-dominance

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
16. S-I- TRY is Diploid organism
S-II- In Grasshopper both type of gametes produce by male is similar

(1) Only S-I correct

(2) only s-II correct

(3) Both S-I & S-I correct

(4) Both wrong

 Sankalp
17. A colour-blind male if marries to carrier female then chance of male to be
Colourblind is

(1) 50%.

(2) 25%.

(3) 30%

(4) 100%.
 Sankalp
18. Not true for law of Dominance

(1) Factor occur in pair

(2) Trait is control By two unit Called Factor

(3) Factor when Dissimilar both Express

(4) Factor show Mixing

 Sankalp
19. Mark the Correct statement

(1) O-Blood group no Antigen

(2) A-Blood Group only one type of Antigen

(3) Polygenic inheritance is quantitative inheritance

(4) all
 Sankalp
20. If a Plant TtRY is crossed with ttrr total seed is 400 than tall Round seed is

(1) 100

(2) 200

(3) 300

(4) 400
 Sankalp
21. Not true for linkage

(1) Directly proportional to parental type

(2) Linkage means two gene have present on chromosome

(3) Eye colour and Wing size are linked trait.

(4) Linkage decrease Recombinant and parental both

 Sankalp
22. According to Mendel’s principle of segregation, gametes always receiv

(1) One pair factor

(2) One quarter of the genes

(3) Both one factor of father and one factor of mother

(4) Only one factor

 Sankalp
23. Select the mismatch

(1) Pleiotropy – multiple phenotypic effect

(2) Test cross – Cross with recessive parent

(3) Polygenic inheritance – Qualitative inheritance

(4) Multiple allele – Blood group

 Sankalp
24. In case of inheritance of one gene 3 : 1 phenotypic ratio can be explained
on the basis of

(1) Incomplete dominance

(2) Co-dominance

(3) Dominance

(4) Linkage
 Sankalp
25. The modified allele is equivalent to the unmodified allele when it
produces–

(1) A non-functional enzyme

(2) No enzyme

(3) The normal enzyme

(4) All of the above

 Sankalp
26. Find out the incorrect match –

(1) F1 resembled one parent – Dominance

(2) F1 resembled in between – Incomplete dominance

(3) F1 resembled both parent – Co-dominance

(4) More than two gene locus – Multiple allele

 Sankalp
27. In tomato, genotype aabbcc produces 100g tomatoes and AABBCC
produces 160g tomatoes. What is contribution of each polygene in the
production of tomatoes?

(1) 10 g

(2) 20 g

(3) 30 g

(4) 40 g
 Sankalp
28. In case of complete linkage in two gene loci located on same chromosome,
result of test cross will give result

(1) Recombinant 25 percent

(2) Parental 100 percent

(3) Recombinant 100 percent

(4) Parental 50 percent

 Sankalp
29. Two genes P and Q are linked and show recombinant 25 percent in test
cross than it implies-

(1) Incomplete linkage

(2) Parental less than 100 percent

(3) Parental more than 50 percent

(4) All
 Sankalp
30. Dominance is not an autonomous feature of gene this implies-

(1) Some genes are always dominant

(2) Some genes are always recessive

(3) Trait is expressed only if gene produce a particular protein, so dominant

and recessive trait is not decide until protein form

(4) All are correct

 Sankalp
31. Select the list of items of Column I with Column II and select the correct
option from the codes given below:
Column – I Column - II
(1) A-ii, B-i, C-iii A Cancer i Chromosomal
aberration
B Klinefelter’s ii Gynaecomastia
(2) A-ii, B-iii, C-i syndrome
C Linkage map iii Sturtevant

(3) A-i, B-ii, C-iii

(4) (4) A-i, B-iii, C-ii

 Sankalp
32. Mendel’s which proposition was not accepted by his contemporaries-

(1) Factors are discrete unit

(2) Alleles do not blend

(3) Factors control expression

(4) Factor occur in pair

 Sankalp
33. In some organisms if only half the sperm have X-chromosome and other
half lack this than type of sex-determination is-

(1) XX-XY

(2) XX-XO

(3) ZZ-ZW

(4) Environmental
 Sankalp
34. Which is correct regarding phenylpyruvate?

(1) Formed in case of PKU

(2) Accumulate in brain, cause mental retardation

(3) Poor absorption by kidney

(4) All of the above

 Sankalp
35. Thalassemia is

(1) Autosomal recessive disease related to chromosome 11 and 17

(2) Autosomal dominant disease

(3) Sex–linked dominant disease

(4) Genetic disorder, recessive, Quantitative disorder

 Sankalp
36. Select the list of items of Column I with Column II and select the correct
option from the codes given below:

(1) A-ii, B-i, C-iii Column - I Column - II

A PKU i Autosomal
B Down’s syndrome ii Trisomic
C Colour blindness iii Male is not carrier
(2) A-ii, B-iii, C-i

(3) A-i, B-ii, C-iii

(4) A-i, B-iii, C-ii

 Sankalp
37. Which of the following is odd among the following option -

(1) Tall plant

(2) Round seed

(3) Axial flower

(4) Seed colour

 Sankalp
38. In mendelian cross which of the following is observation is correct -

(1) only one of the parental traits was expressed in the F1 generation while at
the F2 stage both the traits were expressed in the proportion 3:1

(2) F1 generation is hybrid have phenotype similar to both parent

(3) F2 generation not show two trait

(4) No parental trait in F2 generation

 Sankalp
39. Which of the following is known as linkage:

(1) T and t located on same chromosome

(2) T and t located on different chromosome

(3) T and R located on different chromosome

(4) T and R located on same chromosome

 Sankalp
40. Linked genes can be separated through:

(1) Segregation:

(2) Crossing over

(3) Independent assortment

(4) Linkage
 Sankalp
41. Crossing over can separate.....

(1) Genes of one gene loci

(2) Genes of different gene loci on different chromosome

(3) Genes which are linked

(4) All
 Sankalp
42. Percent of recombinant is directly proportional to:

(1) Linkage

(2) Parental progeny

(3) Chance of crossing over

(4) Strength of linkage

 Sankalp
43. Factor is located on

(1) Gene

(2) chromosome

(3) Chromatin

(4) Both 2 & 3

 Sankalp
44. Law of independent assortment is valid For

(1) Diploid & Mitosis

(2) Diploid & Meiosis

(3) Dihybrid & Meiosis

(4) Monohybrid & Mitosis

 Sankalp
44. Identify the wrong statement with reference to the gene ‘I’ that controls
ABO blood groups.

(1) A person will have only two of the three alleles.

(2) When IA and IB are present together, they express same type of sugar.

(3) Allele ‘i’ does not produce any sugar

(4) The gene (I) has three alleles

 Sankalp
45. Experimental verification of the chromosomal theory of inheritance was
done by:

(1) Sutton

(2) Boveri

(3) Morgan

(4) Mendel
 Sankalp
46. Select the correct match

Column – I Column - II
(1) Phenylketonuria Autosomal dominant trait

(2) Sickle cell anaemia Autosomal recessive trait, chromosome-11

(3) Thalassemia X linked

(4) Haemophilia Y linked

 Sankalp
48. How many true breeding pea plant varieties did Mendel select as pairs,
which were similar except in one character with contrasting traits? (2020)

(1) 2

(2) 14

(3) 8

(4) 4
 Sankalp
49. Chromosomal theory of inheritance was proposed by:

(1) Bateson and Punnet

(2) T.H. Morgan

(3) Watson and Crick

(4) Sutton and Boveri

 Sankalp
50. The number of contrasting characters studied by Mendel for his
experiments was:

(1) 4

(2) 2

(3) 7

(4) 14
 Sankalp
51. The best example for pleiotropy is:

(1) Phenylketonuria

(2) Colour Blindness

(3) ABO Blood group

(4) Skin colour

 Sankalp
52. What map unit (Centimorgan) is adopted in the construction of genetic maps?

(1) A unit of distance between two expressed genes representing 10% cross over.

(2) A unit of distance between two expressed genes representing 100% cross over.

(3) A unit of distance between genes on chromosomes, representing 1% cross over.

(4) A unit of distance between genes on chromosomes, representing 50% cross over
 Sankalp
53. What is the genetic disorder in which an individual has an overall
masculine development gynecomastia, and is sterile?

(1) Turner’s syndrome

(2) Klinefelter’s syndrome

(3) Edward syndrome

(4) Down’s syndrome

 Sankalp
54. The frequency of recombination between gene pairs on the same
chromosome as a measure of the distance between genes was explained by

(1) T.H. Morgan

(2) Gregor J. Mendel

(3) Alfred Sturtevant

(4) Sutton Boveri

 Sankalp
55. In Antirrhinum (Snapdragon), a red flower was crossed with a white flower
and in F1 generation pink flowers were obtained. When pink flowers were
selfed, the F2 generation showed white, red and pink flowers. Choose the
incorrect statement from the following: (2019)

(1) This experiment does not follow the principle of dominance.

(2) Pink colour in F1 is due to incomplete dominance.

(3) Ratio of F2 is 1/2 (Red) : 2/4 (Pink) :1/4 (White)

(4) Law of segregation does not apply in this experiment

 Sankalp
56. Select the incorrect statement

(1) Male fruit fly is heterogametic

(2) In male grasshoppers 50% of sperms have no sex-chromosome

(3) In domesticated fowls, sex of progeny depends on the type of sperm

rather than egg

(4) Human males have one of their sex-chromosome much shorter than the
other
 Sankalp
57. Select the correct statement:

(1) Franklin Stahl coined the term “linkage”.

(2) Punnett square was developed by a British scientist.

(3) Spliceosomes take part in translation.

(4) Transduction was discovered by S. Altman

 Sankalp
58. Which of the following pairs is wrongly matched?

(1) Starch synthesis in pea : Multiple alleles

(2) ABO blood grouping : Co-dominance

(3) XO type sex determination : Grasshopper

(4) T.H. Morgan : Linkage

 Sankalp
59. Which of the following characteristics represent ‘Inheritance of blood
groups’ in humans? (2018)
(a) Dominance (b) Co-dominance
(c) Multiple dominance (d) Incomplete dominance
(e) Polygenic inheritance

(1) b, c and e

(2) a, b and c

(3) b, d and e

(4) a, b and e
 Sankalp
60. A woman has an X-linked condition on one of her X- chromosomes. This
chromosome can be inherited by:

(1) Only daughters

(2) Only sons

(3) Only grandchildren

(4) Both sons and daughters

 Sankalp
61. Among the following characters, which one was not considered by Mendel
in his experiments on pea?

(1) Stem – Tall or Dwarf

(2) Trichomes – Glandular or non-glandular

(3) Seed – Green or Yellow

(4) Pod – Inflated or Constricted

 Sankalp
62. A disease caused by an autosomal primary non-disjunction is

(1) Down’s syndrome

(2) Klinefelter’s syndrome

(3) Turner’s syndrome

(4) Sickle cell anemia

 Sankalp
63. The genotypes of a Husband and Wife are IAIB and IAi. Among the blood
types of their children, how many different genotypes and phenotypes are
possible?

(1) 3 genotypes ; 3 phenotypes

(2) 3 genotypes ; 4 phenotypes

(3) 4 genotypes ; 3 phenotypes

(4) 4 genotypes ; 4 phenotypes

 Sankalp
64. Which one from those given below is the period for Mendel’s hybridisation
experiments?

(1) 1856 - 1863

(2) 1840 - 1850

(3) 1857 - 1869

(4) 1870 - 1877

 Sankalp
65. Thalassemia and sickle cell anemia are caused due to a problem in globin
molecule synthesis. Select the correct statement.

(1) Both are due to a qualitative defect in globin chain synthesis

(2) Both are due to a quantitative defect in globin chain synthesis

(3) Thalassemia is due to less synthesis of globin molecules

(4) Sickle cell anemia is due to a quantitative problem of globin molecules

 Sankalp
66. Select the wrong statement:

(1) Chromosomal Theory of inheritance was proposed by Sutton

(2) Law of Dominance and Law of independent assortment were proposed by Mendel

(3) Linkage and recombination were discovered by Sutton

(4) Three scientists independently rediscovered the Mendel’s laws in 1900

 Sankalp
67. The recessive genes located on X-chromosome in humans are always:

(1) Sub-lethal

(2) Expressed in females

(3) Expressed in males

(4) Lethal
 Sankalp
68. Which one of the following is not true for the experiments of Mendel on pea?

(1) His experiments had small sampling size

(2) He chooses characters of two contrasting states

(3) He used true-breeding lines

(4) His observations were based on natural, open pollination

 Sankalp
69. Select the correct option:

(1) Klinefelter’s syndrome is due to an extra X chromosome and results in sterile male

(2) Phenylketonuria is X linked disease and results in accumulation of phenyl pyruvic

acid

(3) Down’s syndrome is due to triploidy and results in mental retardation

(4) Turner’s syndrome is due to trisomy and results in sterile female

 Sankalp
70. If a colour-blind man marries a woman who is homozygous for normal
colour vision, the probability of their son being colour-blind is:

(1) 0.75

(2) 1

(3) 0

(4) 0.5
 Sankalp
71. A true breeding plant is:

(1) Near homozygous and produces off spring of its own kind

(2) Always homozygous recessive in its genetic constitution

(3) One that is able to breed on its own

(4) Produced due to cross-pollination among unrelated plants

 Sankalp
72. A cell at telophase stage is observed by a student in a plant brought from
the field. He tells his teacher that this cell is not like other cells at
telophase stage. There is no formation of cell plate and thus the cell is
containing more number of chromosomes as compared to other dividing
cells. This would result in:

(1) Aneuploidy

(2) Polyploidy

(3) Soma clonal variation

(4) Polyteny
 Sankalp
73. In a test cross involving F1 dihybrid flies, more parental type off spring
were produced than the recombinant-type off spring. This indicates

(1) The two genes are located on two different chromosomes

(2) Chromosomes failed to separate during meiosis

(3) The two genes are linked and present on the same chromosome

(4) Both of the characters are controlled by more than one gene
 Sankalp
74. Pick out the correct statements:
(1) Haemophilia is a sex-linked recessive disease.
(2) Down’s syndrome is due to aneuploidy.
(3) Phenylketonuria is an autosomal recessive gene disorder.
(4) Sickle cell anemia is an X-linked recessive gene disorder.

(1) (1) and (4) are correct

(2) (2) and (4) are correct

(3) (1), (3) and (4) are correct

(4) (1), (2) and (3) are correct

 Sankalp
75. Match the terms in Column I with their description in Column II and
choose the correct option: Column I Column II
a Dominance i Many genes govern a single
character
Codes b Codominance ii In a heterozygous organism
(1) a-(ii), b-(i), c-(iv), d-(iii) only
one allele expresses itself
c Pleiotropy iii In a heterozygous organism
(2) a-(ii), b-(iii), c-(iv), d-(i) both alleles express
themselves
fully
(3) a-(iv), b-(i), c-(ii), d-(iii) d Polygenic iv A single gene influences
Inheritance many characters

(4) a-(iv), b-(iii), c-(i), d-(ii)

 Sankalp
76. A tall true breeding garden pea plant is crossed with a dwarf true breeding
garden pea plant. When the F1 plants were selfed the resulting genotypes
were in the ratio of:

(1) 1 : 2 : 1 : Tall homozygous : Tall heterozygous : Dwarf

(2) 1 : 2 : 1 : Tall heterozygous : Tall homozygous : Dwarf

(3) 3 : 1 : Tall : Dwarf

(4) 3 : 1 : Dwarf : Tall

 Sankalp
77. Which of the following most appropriately describes hemophilia?

(1) Recessive gene disorder

(2) X-linked recessive gene disorder

(3) Chromosomal disorder

(4) Dominant gene disorder

 Sankalp
78. How many pairs of contrasting characters in pea plants were studied by
Mendel in his experiments?

(1) Eight

(2) Seven

(3) Five

(4) Six
 Sankalp
79. A man with blood group ‘A’ marries a woman with blood group ‘B’. What
are all the possible blood groups of their off spring’s?

(1) A, B, AB and O

(2) O only

(3) A and B only

(4) A, B and AB only

 Sankalp
80. Multiple alleles are present:

(1) At the same locus of the chromosome

(2) On non-sister chromatids

(3) On different chromosomes

(4) At different loci on the same chromosome

 Sankalp
81. The movement of a gene from one linkage group to another is called:

(1) Translocation

(2) Crossing over

(3) Inversion

(4) Duplication
 Sankalp
82. Alleles are

(1) Different molecular forms of a gene

(2) Heterozygote’s

(3) Different phenotype

(4) True breeding homozygote’s

 Sankalp
83. An abnormal human baby with ‘XXX’ sex chromosomes was born due to:

(1) Fusion of two ova and one sperm

(2) Fusion of two sperms and one ovum

(3) Formation of abnormal sperms in the father

(4) Formation of abnormal ova in the mother

 Sankalp
84. In sea urchin DNA, which is double stranded, 17% pf the bases were
shown to be cytosine. The percentage of the other three bases expected
to be present in this DNA are: (2015)

(1) G-17%, A-33%, T-33%

(2) G-8.5%, A-50%, T-24.5%

(3) G-34%, A-24.5%, T-24.5%

(4) G-17%, A-16.5%, T-32.5%

 Sankalp
85. A colour blind man marries a woman with normal sight who has no history
of colour blindness in her family. What is the probability of their grandson
being colour blind?

(1) 1

(2) Nil

(3) 0.25

(4) 0.5
 Sankalp
86. The term “linkage” was coined by:

(1) T. Boveri

(2) G. Mendel

(3) W. Sutton

(4) T.H. Morgan

 Sankalp
87. A gene showing co-dominance has: (2015 Re)

(1) Alleles tightly linked on the same chromosome

(2) Alleles that is recessive to each other

(3) Both alleles independently expressed in the heterozygote

(4) One allele dominant on the other

 Sankalp
88. A pleiotropic gene:

(1) Is a gene evolved during Pliocene

(2) Controls a trait only in combination with another gene

(3) Controls multiple traits in an individual

(4) Is expressed only in primitive plants

 Sankalp
89. In his classic experiments on pea plants, Mendel did not use:

(1) Pod length

(2) Seed shape

(3) Flower position

(4) Seed colour

 Sankalp
90. Fruit colour in squash is an example of:

(1) Inhibitory genes

(2) Recessive epistasis

(3) Dominant epistasis

(4) Complementary genes

Sankalp