Professional Documents
Culture Documents
Basic Physics of Ultrasound
Basic Physics of Ultrasound
M
MACMILLAN
II:) Matthew Hussey 1985
Preface X
Acknowledgements Xl
Appendixes
Index 233
Preface
I wish to thank sincerely the following, who helped to complete this work:
(a)
(b) ' - -_ _
Figure 1.1 Some examples of B-mode ultrasound images. (a) A foetal head with
portions of trunk, arm and fist. (b) A longitudinal section through the abdominal aorta
showing some of the branches. (c) A section through the liver showing dilated hepatic
veins
4 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
ment of the blood flow out of the heart in the arch of the aorta, the cardiac
output.
The abdominal aorta is readily imaged with general purpose B-mode
ultrasound imaging devices. In many patients certain of the branches and
smaller arteries in the abdominal region may also be imaged and Doppler
techniques applied to measure the blood flow within them.
Ultrasound is invaluable for the imaging of the abdominal organs-
liver, kidneys, spleen, pancreas, biliary tree -.. their mutual positioning and
interconnections. Nowadays this part of the body is the major region in-
vestigated with imaging ultrasound techniques.
Another major area of interest in medical diagnostic ultrasound is ob-
stetrics. Doppler ultrasound may be used to detect early foetal heart motion
and is also widely used to monitor the foetal heartbeat during labour. It has
also been used to study placental blood flow. Imaging methods are very
widely used for monitoring foetal growth, for studying the foetal head,
neural tube, abdominal organs as well as for determining the position and
orientation of the foetus within the womb.
Doppler ultrasound is coming to be increasingly used in the detection and
measurement of blood flow in arteries and veins throughout the body.
Doppler ultrasound measurements are also used to characterise the state of
arteries - stiffness, stenosis, aneurysm, collateral flow, etc.
Reliable use of diagnostic ultrasound in all of these medical specialities
requires a knowledge of the nature of ultrasound, how it behaves as it
travels through the body tissues as well as the main features and functioning
of the actual ultrasound equipment. A keen appreciation of the limitations
of ultrasound techniques is also a requirement.
Because ultrasound methods are complementary to some diagnostic
techniques and superior to others, an appreciation of the role of ultrasound
in the wide battery of diagnostic procedures is also desirable.
as the first in any battery of diagnostic tests. This would certainly be the case
where the alternatives involve surgery or even puncturing the skin, ionising
radiation, or injection/ingestion/inhalation of a foreign substance into the
body.
Because ultrasound interrogates the mechanical properties of the body,
in particular of the deep structures, it may be viewed as an extension, albeit
a sophisticated one, of the traditional palpatory techniques of medicine.
A number of new developments in diagnostic ultrasound, in particular the
emerging possibilities for tissue characterisation, help to deepen the diag-
nostic information obtainable from ultrasound examinations. Therefore the
currently growing applications of ultrasound in medical diagnosis can be
expected to continue to grow and expand in the years ahead.
A prerequisite for this continued growth and development is increasing
the knowledge about the basics of ultrasound physics and the technology of
the diagnostic equipment, among the medical practitioners and associated
technicians in the field.
The primary aim of this book is to describe the basic physics of ultrasound
in so far as it is applied in medical diagnostic equipment. The next aim is to
describe the ways in which this fundamental knowledge is harnessed and
applied in the design of diagnostic equipment and in the use of such equip-
ment.
This material is covered with the minimum of mathematics. Some basic
mathematics and technical matter are accumulated in appendixes at the end
of the book. A person with an 'O'-Ievel in Physics or Mathematics should
not have difficulty with the standard of the subject matter in this text.
The book contains a digest of the most widely available types of diagnostic
ultrasound equipment. But there are many specialised and even research
units in use in hospitals and clinical laboratories which are not described.
However, the fundamentals actually covered should allow the student or
general reader to follow fairly readily the operation and controls of such
special equipment.
A number of physical quantities are discussed and utilised in this book and
occasionally represented with symbols. For reference, table 1.1 lists these
quantities, their symbols and units.
THE SCOPE OF MEDICAL DIAGNOSTIC ULTRASOUND 7
Table 1.1 The Quantities Used in this Book, their Units and Symbols
1.7 BIBLIOGRAPHY
Journals
Acta Ohstetrica et Gynecologica Scandinavica
Acustica
A merican Journal of Ohstetrics and Gynecology
A merican Journal of Roentgenology
British Journal of Ohstetrics and Gynaecology
British Journal of Radiology
European Medical Ultrasonics
Journal of Clinical Ultrasound
Journal of Medical Engineering and Technology
journal of the Acoustical Society o(America
Medical Ultrasound
Radiology
Ultrasonics
Ultrasound in Medicine and Biology
8 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
Annual Reviews
Bock, J. and Ossoinig, K. (Eds), Ultrasonographia Medica, Verlag der Wiener
Medizinischen Akademie, Vienna
Clinical Ultrasound Purchasers Catalogue
Case Studies in Diagnostic Sound, Churchill Livingstone, Edinburgh
Kurjak, A. (Ed.), Progress in Medical Ultrasound: Reviews and Comments, Excerpta
Medica, Amsterdam
Kurjak, A. (Ed.), Recent Advances in Ultrasound Diagnosis, Excerpta Medica, Am-
sterdam
Case Studies in Diagnostic Ultrasound, John Wiley, New York
Linzer, M. (Ed.), Ultrasonic Tissue Characterization, U.S. National Bureau of Stand-
ards, Washington
Winsberg, F. (Ed.), Clinical Ultrasound Review, John Wiley, New York
White, D. N. (Ed.), Ultrasound in Medicine, Plenum Press, New York
Whitehouse, W. M. (Ed.), The Year Book of Diagnostic Radiology, YB Medical Pub-
lishers, New York
Various editors, Acoustical Imaging, Plenum Press, New York
Various editors, Clinics in Diagnostic Ultrasound, Churchill Livingstone, New York
Dunn, F. and O'Brien, W. D., Jr. (Eds), Ultrasonic Biophysics, Dowden Hutchinson &
Ross Inc., Stroudsburg, Pa, 1976
Edmonds, P. D. (Ed.), Ultrasonics, Academic Press, New York, 1981
Hussey, M., Diagnostic Ultrasound: An Introduction to the Interactions Between Ultra-
sound and Biological Tissues, Blackie & Son, Glasgow, 1975
Kinsler, L. E. and Frey, A. R., Fundamentals of Acoustics, 3rd edn, John Wiley, New
York, 1982
Kremkau, F. W., Diagnostic Ultrasound: Physical Principles and Exercises, Grune &
Stratton, New York, 1980
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
Millner, R. (Ed.), Ultrasound Interaction in Biology and Medicine. Plenum Press, New
York,1983
Moores, B. M. et al. (Eds), Physical Aspects of Medical Imaging, John Wiley, Chichester,
1981
Preston. K. et al. (Eds), Medical Imaging Techniques: A Comparison, Plenum Press,
New York. 1979
Repacholi, M. H. and Benwell, D. A. (Eds), Essentials of Medical Ultrasound,
Humana, Clifton, N.J., 1982
Rose. J. L. and Goldberg. B. B .• Basic Physics in Diagnostic Ultrasound, John Wiley,
New York, 1979
Stroke, G. W. et al. (Eds), Ultrasonic Imaging and Holography: Medical, Sonar and
Optical Applications. Plenum Press, New York, 1974
Wells. P. N. T. and Ziskin. M., New Techniques and Instrumentation in Ultrasono-
graphy, Churchill Livingstone. Edinburgh. 1980
Woodcock, J. P., Ultrasonics. Adam Hilger Ltd, Bristol. 1979
Ultrasound in Ophthalmology
Fram;ois, J. and Goes, F., Ultrasonography in Ophthalmology, S. Karger, Basel, 1975
Hassani, S. N. (with Bard, R. L.), Real Time Ophthalmic Ultrasonography, Springer
Verlag, New York, 1978
Vanysek, J. et aI., Ultrasonography in Ophthalmology, Butterworths, London and
Prague, 1972
Cardiological Applications
Benchimol, A., Non-invasive Techniques in Cardiology for the Nurse and Technician,
John Wiley, New York, 1978
Chang, S., Echocardiography: Techniques and Interpretation, 2nd edn, Lea & Febiger,
Philadelphia, 1981
Feigenbaum, H., Echocardiography, 3rd edn, Lea & Febiger, Philadelphia, 1981
Gutesell, H. P. and Paquet, M., Atlas of Pediatric Echocardiography, Harper & Row,
Lindenlaan, Holland, 1978
Harrison, D. C. et al. (Eds), Cardiovascular Imaging and Image Processing: Theory and
Practice-1975, Society of Photo-Optical Instrumentation Engineers, Palos Verdes
Estates, Ca, 1975
Kisslo, J. A. (Ed.), Two-dimensional Echocardiography, Churchill Livingstone, New
York, 1980
Linhart, J. W. and Joyner, C. R., Diagnostic Echocardiography, C. V. Mosby Co., St
Louis, Mo, 1981
Meyer, R. A., Pediatric Echocardiography, Lea & Febiger, Philadelphia, 1977
Miskovits, c., Echocardiography: A Manual for Nurses, Medical Examination
Publishing Co. Inc., Flushing, NY, 1977
THE SCOPE OF MEDICAL DIAGNOSTIC ULTRASOUND 11
Miscellaneous Applications
Evans, K. T. and Gravelle, 1. H., Mammography, Thermography and Ultrasonography
in Breast Disease, Butterworths, London, 1973
Goldberg, B. B. (Ed.), Ultrasound in Cancer, Churchill Livingstone, Edinburgh, 1981
Haller, J. O. and Shkolnik, A. (Eds), Diagnostic Ultrasound in Pediatrics, Churchill
Livingstone, Edinburgh, 1981
Holm, H. H. and Kristensen, P., Ultrasonically Guided Puncture Technique, W. B.
Saunders Co., Philadelphia, 1981
Kobayashi, T., Clinical Ultrasound of the Breast, Plenum Press, New York, 1978
Rhyne, T. L., Acoustic Instrumentation and Characterisation of Lung Tissue, Research
Studies Press, Forest Grove, Or, 1977
Sigel, B., Operative Ultrasonography, Lea & Febiger, Philadelphia, 1982
Taylor, K. J. W. and Viscomi, G. N., Diagnostic Ultrasound in Emergency Medicine,
Churchill Livingstone, Edinburgh, 1981
Thijssen, J. M. (Ed.), Ultrasonic Tissue Characterization: Clinical Achievements and
Technological Potentials, Stafleu's Scientific Publishing Co., Brussels, 1980
2 Basic Features of
U Itrasou nd Propagation
This chapter deals with the basic ideas and aspects of ultrasound as it travels
through a medium. The main questions addressed are the following: what
are sound and ultrasound, what does the medium through which the ultra-
sound is passing do to the ultrasound, and finally, what does the ultrasound
do to the medium?
After reading this chapter the student should be able to:
(a) describe the main features of a sound wave disturbance;
(b) discuss the factors that affect speed of propagation and acoustic
impedance;
(c) distinguish between sound and ultrasound;
(d) define intensity and Intensity Level (the decibel scale);
(e) describe perpendicular reflection and transmission at a plane bound-
ary;
(f) discuss oblique incidence at a plane boundary and the consequent
reflection and refraction;
(g) describe scattering;
(h) discuss the mechanisms of absorption and its consequences;
(i) describe attenuation, its causative mechanisms, its quantification in
tissues and its frequency dependence in tissues.
ORIGINAL POSITION
\ DISPLACEMENT
Figure 2.1 The oscillatory displacement of each particle of the medium carrying the
sound wave, as a function of time. The displacement is along the same direction as the
wave is travelling and the particle oscillation is repeated once each period, T
If one end of a piece of string is tied rigidly and the other end is loose and
if the loose end is shaken vertically up and down, a wave travels along the
string. The wave consists of vertical vibrations of the individual parts of the
string. But these particles of the string do not move along the string. They
remain in their original positions when the vibration of the loose end of the
string is stopped.
In both of these examples, while energy travels from the source of the
disturbance to a remote location, the particles of the medium do not move
in this way. Figure 2.2 illustrates what happens to the particles of the medium
when a sound wave is initiated. The particles close to the source are first
driven into vibration. Subsequently particles more remote from the source
experience the disturbance and begin to vibrate. The fact that the direction
of vibration of the particles and the direction of motion of the wave are the
14 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
0 0 0 0 0
0
0 0
-----0-
0
0
0 Z
0 0
(a) 0 0 0
0 0
~ <1-0-<> 0 0 0
0
4-O-t> 0
0 -----0-
0 Z
<I-<H>
0 0 0
(b) ~ 0 0
0
4-<>P ~ <1-0-1> 0 0
<1-0-1>
<1-0-1> 0
-----0-
<1-0-1>
0 Z
<1-0-<>
~ <1-0-1> 0
0
(c) <1-0-1> <1-0-1> 0
Figure 2.2 As the plane sound wave propagates along the z direction the particles of
the medium initially undisturbed (a). are driven into vibration of successively farther
distances along this direction (b). (c) and (d)
same, makes this wave a longitudinal wave. The fact that all of the particles
in a plane perpendicular to the direction of travel of the wave move in unison
gives rise to the description plane longitudinal wave for this type of sound
wave. In the water wave described above, the particles of the water vibrate
in a direction perpendicular to the direction of movement of the wave and
therefore. that wave is described as a transverse wave.
Within the medium through which the sound is travelling, there are
regions towards which the particles are moving from both directions as well
as regions away from which the particles are moving in both directions. The
former regions therefore, experience an elevation of pressure and are de-
scribed as compressions. The latter regions experience a reduction in pressure
and are referred to as rarefactions. As the wave propagates, the compressions
and rarefactions also travel along so that from one moment to the next each
region of the medium experiences compressions and rarefactions in turn. It
is possible to conceive of the source of the sound as being the source of
successive compressions and rarefactions, with these pouring out from the
source and travelling in the direction of the receiver. A complete cycle of the
disturbance therefore consists of a compression followed by a rarefaction up
BASIC FEATURES OF ULTRASOUND PROPAGATION 15
RAREFACTION
I
I I
I
1I..l.?~~R~SI?~
IIIIII I I
I
I
I 110000
1111111
I
I
I
I
I I I 11111 I I I 1111111 I I I
1111111 I I 1111111 I I
I r 11111 I I I 1111111 I J
I 111111 I I I 11111111 I I
~
Z
PRESSURE~---r-C\_:<J~A--+-6_":~.
, \J ~
Figure 2.3 At anyone instant in the sound wave, the compression/rarefaction/
compression sequence extends along a wavelength, },' in the direction of travel of the
wave. The elevations in acoustic pressure correspond to compressions of the medium
while the reductions in this pressure correspond to the rarefactions in the medium
BELL
JAR
BELL
TO VACUUM PUMP
Figure 2.4 A source of sound, an electric bell, located under a glass jar in which a
vacuum may be established
BASIC FEATURES OF ULTRASOUND PROPAGATION 17
2.3 ULTRASOUND
Table 2.1 Values of Speed of Propagation in some Biological Tissues and Media,
together with Values of Wavelength at 1 MHz and 10 MHz
1 MHz 10MHz
\
ULTRASOUND y,,\
f
WAVE
\ /
~P~RO~PA~G~A~J~IO~N ________________~~
Figure 2.5 A portion of the ultrasound wave passing through a unit area of 1 m 2
perpendicular to the direction of propagation of the wave
18 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
in watts per square metre. The more intense the ultrasound wave, the more
energy is transported each second through each square metre, but also the
greater the vibratory disturbance of the medium and the greater the excess
pressure developed at each location in the medium disturbed by the wave.
Table 2.2 Comparison of Linear Ratio Scale and Logarithmic (dB) Scale
dB Scale
10 10 100
104 40
10 2 20
10 10
3.16 5
1.26 1
1.0 o
0.79 -1
0.32 -5
0.1 -10
10 - 2 -20
10-4 -40
10- 10 -100
BASIC FEATURES OF ULTRASOUND PROPAGATION 19
Up to this point in the discussion, the medium through which the ultrasound
is travelling has been assumed to be homogeneous and unbounded. If there
is a boundary or an interface between one medium and another, this can
drastically effect the propagation of the ultrasound wave. Consider the
situation shown in figure 2.6, where the boundary is plane and perpendicular
to the direction of propagation of the ultrasound wave. This boundary
separates two media which are different by virtue of having different values
of acoustic impedance (Z) (equations 2.6 and 2.7)
(2.6)
and
(2.7)
MEDIUM 1
Z,
I,
Figure 2.6 Specular reflection and transmission at a plane boundary between two
acoustically different media, on which the in-coming wave is perpendicularly incident
(2.8)
flected wave travels back into the first medium from the boundary, but not
along the same line as the incident wave. The angle of reflection (8 r ) is equal
to the angle ()fincidence (8), and the reflected wave is on the opposite side of
the perpendicular line or normal to the boundary at the point of incidence.
Neither does the transmitted wave continue along the same line of propa-
gation as it originally occupied in the first medium. It is refracted and the
z,
Figure 2.7 Specular reflection and transmission at a plane acoustic interface on which
the wave is obliquely incident
(2.11 )
Figure 2.8 The angle of transmission B, as a function of the angle of incidence Bi • for
different values of the ratio of the propagation speeds, C 2 /C 1
(2.12)
22 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
The intensity transmission coefficient T may be derived as in equation (2.13),
It
T=-
Ii
=1-R
4(Z 1/cos8J(Zz/cos8t)
(2.13)
(Z 1/cos8i + Zz/cos8Jz
If the boundary between the two media is convex as in figure 2.9(a), the
refraction experienced by the transmitted wave varies with vertical distance
from the central axis AN. The transmitted wave is concentrated or focussed
some distance into the second medium. Also the reflected wave returns into
the first medium as a divergent wave. If the boundary is concave as in
figure 2.9(b), the transmitted wave is divergent and the reflected wave is
focussed.
z,
A --~-----+-------i;'A
(a)
z,
(b)
Figure 2.9 (a) A convex acoustic boundary causes focussing of the transmitted wave
and divergence of the reflected wave. (b) A concave boundary produces divergence of
the transmitted wave and convergence or focussing of the reflected wave
In both of these cases the focussing and diverging action is strongly de-
pendent on the radius of curvature of the boundary. The smaller the radius
of curvature the sharper the focussing action and the closer to the boundary
along the axis is the focus in each case.
BASIC FEATURES OF ULTRASOUND PROPAGATION 23
2.6 SCATTERING
If the boundary between two media has surface irregularities of the order of
magnitude of the wavelength or less, then the reflected wave is fragmented
into random directions relative to the boundary. This is shown in figure 2.10.
If there are small (order of wavelength or less) reflecting inhomogeneities
in the medium, similar scattering can occur in every direction and the in-
tensity of the wave beyond the inhomogeneities is reduced relative to that
before the inhomogeneities. This is shown in figure 2.II.In this way, scatter-
ing reduces the intensity in the ultrasound wave. It also produces along the
original direction of travel of the wave, the so-called back-scattered waves.
Figure 2.10 When the reflecting surface has roughnesses of the order of magnitude of
the wavelength of the ultrasound, the reflection is no longer specular but consists of
less directional scattering
>I
INCI=D_E_NT-j;;~~_~~
WAVE ~ ~
-~-~
Figure 2.11 Scattering occurs if discrete reflectors of the order of magnitude of the
ultrasound wavelength. or smaller, are located in the incident wave
2.7 ABSORPTION
ADVANCED DURING
.....-------...
COMPRESSION
0~G
RELAXATION DURING
RA~FACTION
Figure 2.12 An equilibrium between two energy states, A and B, which may be
different chemical reactants or physical states of a material, may be disturbed by the
ultrasound wave. Energy from the wave may drive the reaction to the right during the
compression phase but not all of this energy is recovered by the wave during the rarefac-
tion phase when the reaction relaxes leftwards too slowly
2.8 ATTENUATION
,,...
;.
.4
;. r IiO'
-t-
~
EOo
SCATTERING
.,
~~
IiO'
90
i
IiO'
REFLECTION
~
I ~
/
EOo
\
OVERALL E;Io
ATTENUATION
,lo 41
EOo /
Figure 2.13 A schematic representation of how the main mechanisms of attenuation
act. In absorption, ultrasound energy is converted to heat all along the path of the wave,
thereby resulting in reduction of ultrasound intensity along the path. Scattering occurs
at small reflectors in the wave and results in reflection of the ultrasound energy away
from the original propagation path, thereby reducing the intensity downstream. In
specular reflection some of the energy in the wave is reflected backwards, thereby
reducing the intensity downstream. In general in tissues all of these mechanisms act
simultaneously
as the tissues of the body, all three of these mechanisms come into play to one
extent or another and produce an overall attenuation of the wave.
This attenuation is manifested as an exponential decline of intensity (I)
with distance (z) travelled by the wave (equation 2.14)
(2.14)
This relationship is illustrated in figure 2.14. 10 is the initial value of the
intensity at z = 0 while 0( is the overall intensity attenuation coefficient (see
Appendix A). The intensity declines by a factor of 0.5 in every (0.7/0() (m),
the half-value thickness in the medium. Thus the greater the value of the
attenuation coefficient the more rapid is the decay, as shown in figure 2.14,
and the shorter the half-value thickness.
Since overall attenuation is caused by the combination of absorption,
26 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
z
Figure 2.14 Attenuation results in exponential decline of the ultrasound intensity
with distance travelled. IX is the attenuation coefficient
INTENSITY
LEVEL (dB)
112 > III
z(m)
Figure 2.15 The attenuation which occurs with distance, z, may be represented as a
linear reduction of the Intensity Level in dB (reference intensity taken as the initial
intensity, 10)' The steeper slope, higher value of /-l, relates to a more highly attenuating
medium
BASIC FEATURES OF ULTRASOUND PROPAGATION 27
Table 2.4 Values of Logarithmic Attenuation Coefficient at 1 MHz for some Tissue
Types
Water 0.002
Blood 9
Fat 60
Brain 90
Nerve 90
Muscle 350
Liver 90
Kidney 90
Aqueous Humour 7
Lens 250
Lung 4100
Bone 870
Il (dB/m)
10'
MUSCLE
BRAIN FAT
LIVER
lONE
10~--------~----------~------
.1 10 f (MHz)
Figure 2.16 The attenuation characteristics of most tissues increase as the frequency
mcreases
28 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
2.9 BIBLIOGRAPHY
Dunn. F. and O·Brien. W. D .. Jr. (Eds). Ultrasonic Biophysics. Dowden. Hutchinson &
Ross Inc .. Stroudsburg. Pa. 1976
Edmonds. P. D. (Ed.). Ultrasonics. Academic Press, New York, 1981
Ensminger. D .. Ultrasonics. Marcel Dekker Inc., New York, 1973
Hazzard. D. G. and Litz. M. L., Biological Effects and Characterizations of Ultrasound
Sources. Castle House Publications Ltd. 1979
Hussey. M .. Diagnostic Ultrasound: an Introduction to the Interactions between Ultra-
sound and Biological Tissues. Blackie & Son, Glasgow, 1975
Kinsler. L. E. and Frey, A. R .. Fundamentals o{Acoustics. 3rd edn. John Wiley, New
York. 1982
Kremkau, F. W., Diagnostic Ultrasound: Physical Principles and Exercises. Grune &
Stratton. New York. 1980
McDicken. W. N .. Diagnostic Ultrasonics: Principles and Use o{Instruments, 3rd edn,
John Wiley. New York. 1981
Millner. R. (Ed.). Ultrasound Interaction in Biology and Medicine. Plenum Press. New
York. 1983
Rose. J. L. and Goldberg. B. B .. Basic Physics in Diagnostic Ultrasound, John Wiley.
New York. 1979
de Vlieger. M .. White. D. N. and McCready. V. R., Ultrasonics in Medicine, Excerpta
Medica. Amsterdam, 1974
de Vlieger. M. et al. (Eds). Hamlhook of Clinical Ultrasound. John Wiley. New York.
1978
Wells. P. N. T .. Biomedical Ultrasonics, Academic Press, London, 1977
White. D. N. (Ed.). Recent Advances in Ultrasound in Biomedicine. Vol. I, Research
Studies Press, Forest Grove, Or. 1977
Woodcock. J. P .. Ultrasonics. Adam Hilger Ltd. BristoL 1979
Annual Reviews
Linzer. M. (Ed.). Ultrasonic Tissue Characterization, U.S. National Bureau of Stan-
dards. Washington, annually since 1976
3 Generating and Detecting Ultra-
sound
In this chapter the basic means of creating and detecting ultrasound are dis-
cussed, together with the structure and operation of diagnostic transducers,
the ultrasound beam produced by these transducers and the main ways of
checking their performance.
After reading this chapter the student should be able to:
(a) describe the piezoelectric effect;
(b) discuss the roles of half-wavelength resonance, damping and quarter-
wavelength matching in the operation of a piezoelectric transducer;
(c) draw the beam, with near field and far field, produced by a circular
transducer;
(d) show the ways of focussing such a beam by a refractive lens, by
internal crystal shaping and by a reflecting mirror arrangement;
(e) describe how a transducer may be operated in continuous wave
mode;
(f) show the ways that such a transducer may be driven in pulsed mode
and discuss the factors that affect pulse duration;
(g) broadly describe how the beam from a rectangular crystal differs
from the circular beam;
(h) describe a multi-element array transducer probe;
(i) show how composite beams from an array transducer can be elec-
tronically focussed;
(j) discuss the role of the piezoelectric transducer as a receiver/detector
of ultrasound;
(k) briefly describe the operation of a thermometer, a radiation balance
and liquid crystal layers as detectors of ultrasound;
(I) appreciate the need for measures to take care of the transducer probe;
(m) describe methods for testing the beam and measuring the overall
average intensity and the spatial and temporal distributions of in-
tensity, produced by a transducer.
30 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
At the heart of all the diagnostic instruments used to generate and receive
ultrasound waves are crystals which display the property of piezoelectricity.
This property may be illustrated by considering the flat disc of the crystal
illustrated in figure 3.1. This crystal has a conducting silver alloy layer on
each of the opposite parallel faces. The piezoelectric effect has two comple-
mentary attributes.
(a) VOLTAGE +
+
PRESSURE
(b)
STRAIN +
+
VOLTAGE
(c)
Figure 3.1 (a) A piezoelectric disc has electrodes on the two parallel faces, with
electrical connections soldered to these electrodes. (b) When a stress or pressure is
applied across such a disc, a strain results and also a voltage develops between the
electrodes. The voltage is proportional to the pressure, whether the pressure is
positive or negative. This is the forward piezoelectric effect. (c) When a voltage is
applied across the piezoelectric disc, a strain develops across the thickness. This strain
is proportional to the voltage, whether the voltage is positive or negative. This is the
reverse piezoelectric effect
GENERATING AND DETECTING ULTRASOUND 31
across the crystal, it causes the thickness of the crystal to change, i.e. the
crystal is deformed or strained. The magnitude of the strain is directly
proportional to the voltage applied. When there is no voltage, there is no
strain. When the voltage is reversed in polarity the strain is also reversed in
polarity. If the voltage applied is an alternating voltage, so also is the
resulting strain, and that strain alternates in step with the applied voltage.
The transducer probe is the mount, or housing, for the appropriate piezo-
electric crystal disc. Most commonly, the transducer discs are circular or
semicircular but rectangular transducers also find application. One import-
ant dimension of the disc is its thickness, which determines the resonant
frequency of the disc or the frequency of maximum sensitivity of the disc.
For a disc of constant thickness subjected to an alternating voltage of con-
stant amplitude but varying frequency, the amplitude of the strain behaves
as shown in figure 3.2(a). At a particular frequency, the fundamental fre-
quency fo, which is related to the thickness of the disc (d) by equation (3.1):
.f~ = c/2d (3.1)
STRAIN
(a)
f (Hz)
VOLTAGE
(b) f (Hz)
Figure 3.2 The resonant behaviour of the piezoelectric disc: (a) In response to an
alternating voltage of constant amplitude and increasing frequency, the alternating
strain amplitude undergoes resonances atio' 3io' Sio' etc. (b) In response to an alter-
nating pressure of constant amplitude and increasing frequency, the alternating voltage
amplitude experiences resonances at i o' 3io' Sio' etc.
GENERATING AND DETECTING ULTRASOUND 33
the disc undergoes maximum strain. The piezoelectric disc resonates. As the
frequency is further increased, other strain resonances occur at higher odd
harmonic frequencies, i.e . at 3fo, 5fo, 7j~, etc.
Equation (3.1) may be re-arranged tus,
d=c/2fo (3.2)
= Ao/2
PL ASTIC FACING
CRYSTAL HOUSING
A IR or
PLASTIC ELECTRICAL
CONNECTIONS
PLASTIC FACING
Figure 3.4 The construction of a transducer probe, incorporating the crystal with
electrodes and electrical connections, the housing , the front facing and the damping
backing block, for pulsed operation
protect the crystal from scratching and impact. Scratching could remove the
electrode layer and impact forces could shatter the brittle crystal. The second
purpose is to provide acoustic coupling between the crystal and the body
tissue medium into which ultrasound is to be transmitted. Strong reflection
prevents good coupling, and this would occur iffor instance, the crystal were
placed directly on the skin . This is because the acoustic impedance of the
transducer crystal material is much greater than that of the skin. For opti-
mum coupling between the two , a layer of material having an acoustic
impedance Z" which is equal to the geometrical mean of the two impedances
involved, is required . This criterion is shown in equation (3.3) :
(3 .3)
where Z c and Z s are the acoustic impedances of the crystal material and skin
respectively. An epoxy resin may be formulated with added. aluminium
powder to have this requisite acoustic impedance.
If, furthermore, the thickness of this plastic matching layer is set to one
quarter-wavelength at the working frequency , usually fo , the fundamental
resonant frequency of the crystal , perfect transmission of the ultrasound of
that frequency occurs through the layer in both directions. The installation
of such a layer ensures so-called quarter-wavelength matching between
crystal and skin.
If the transducer is to be used to generate and/ or receive continuous wave
ultrasound , then this may be all there is to the transducer probe, as shown in
figure 3.3. Often a plastic plug is installed behind the crystal for ease of con-
struction . If the transducer is to be used for pulsed mode operation, a further
element is required in the transducer probe as shown in figure 3.4. This
element is a damping layer behind the back face of the crystal. It consists
usually of a plug of an epoxy resin packed with tungsten metal powder. It
extracts and absorbs some of the energy associated with the crystal and so
helps to reduce the duration of pulsed ringing of the crystal.
Some additional damping is often incorporated in the form of a small
electrical resistance in parallel with the transducer crystal. This electrical
GENERATING AND DETECTING ULTRASOUND 35
STRAIN
(a)
f
VOLTAGE
(b)
f
Figure 3.5 The damped resonant behaviour of a piezoelectric disc with damping
backing block: (a) Same situation as in figure 3.2 (a), the resonance is less high and is
spread over a wider range of frequency atIo' 310 , 510 , etc. (b) Under the same circum-
stances as in figure 3.2 (b), each resonance is less high and less sharp
r·
r
- - - - - - - - - - - - - - - - - - - - - - - - -A;)(-t5- -
L·~------K.:
I
~"=l<lf----- Zn.f.----cC:O~...:
I
d I C'
NEAR FIELD : FAR FIELD
Figure 3.6 A cross-sectional cut through a diameter of the circularly symmetrical
ultrasound beam produced by a circular transducer of radius r, under continuous wave
operation. The beam may be broadly divided into the Near Field and the Far Field
~ax
o 2
z (m)
Figure 3.7 Along the beam axis, the z axis, the amplitude of the ultrasound pressure
fluctuates between a maximum and zero within the Near Field. The variation shown
refers to a transducer of 5 mm radius transmitting at 10 MHz into water. The actual
number of such fluctuations and their locations along the axis would depend on both
the radius and the frequency
GENERATING AND DETECTING ULTRASOUND 37
the pressure on the axis occur. Where the last of these pressure amplitude
maxima on the axis occurs is the point of transition from near field to far
field.
The length of the near field (zn.r.> is a function of ultrasound frequency (f)
and transducer disc radius (r), as well as the speed of propagation of
ultrasound, as shown in equation (3.4):
r2f c
Z ----
nf. - C 4f
Ie 4
r2
~ T at ultrasound frequencies (3.4)
Table 3.1 shows the values of the length of the near field for a number of
ultrasound frequencies and disc radii for ultrasound propagation in water at
3TC.
In the far field, where the beam is diverging, the amplitude of the pressure
variation varies in extremely complicated ways depending upon the frequency
and the diameter of the crystal as illustrated in figure 3.8. When the radius of
the crystal is reduced, more sidelobes tend to develop. This means that there is
some of the power in the be?m in pockets to the side of the main lobe. It is the
main lobe that is depicted in figure 3.6. The angle of divergence of the far field
15, shown in figure 3.6, depends on the same three parameters controlling the
length of the near field, as indicated by equation (3.5):
. " 0.61 c
sin u = - -
fr
0.6l1c
(3.5)
r
Various relevant values of this angle are tabulated in table 3.1.
Table 3.1 Lengths of Near Field (zn f) and Angle of Divergence in Far Field (b) in
Water at 37 C
G
MAIN LOBE
Figure 3.8 Two of the complications of the Far Field of an ultrasound beam are the
divergence of the main lobe of the beam, as indicated in figure 3.6, and the emergence of
side lobes, which take some of the energy available and are not directed along the axis.
The number and actual directionality of the side lobes depend on transducer radius and
the operating frequency
3.6 FOCUSSING
C YSTAL
(a) FOCAL
ZONE
CRYSTAL
(b)
MIRROR
(c)
Figure 3.9 The main techniques for focussing the beam of ultrasound produced by a
single-element transducer: (a) Refraction at the front surface of the converging lens
directs the outer portions of the beam towards the axis, thereby effecting focussing.
(b) A bowl-shaped crystal similarly directs the outer parts of the beam towards the
axis, thereby producing the so-called internal focussing.
(c) The diverging beam from a small transducer when reflected from a spherical or
paraboloidal mirror, produces convergence or focussing of the beam
It is not possible with ultrasound to achieve a very small focal point or focus,
rather a focal zone of finite cross-sectional area and also of some length is
what occurs.
The transducer, of the type shown in figure 3.3, may be caused to transmit
ultrasound continuously if it is constantly supplied with an appropriate
alternating voltage. For the maximum output ultrasound intensity, the fre-
quency of this alternating voltage must match the resonant frequency of the
crystal, as determined by the thickness of the crystal. Such an alternating
voltage may be generated by an electronic oscillator. This is the mode of
operation used in most diagnostic Doppler instruments.
A transducer such as that shown in figure 3.4, may be pulse excited simply
by discharging a capacitor through the transducer crystal. The circuit dia-
gram for achieving this is shown in figure 3.10. The capacitor is first charged
to a high voltage, perhaps 500-1500 V. Then as required, the capacitor is
discharged through the crystal, through a switch S2. This switch is an
Figure 3.10 The basic elements in the circuit used to pulse-excite the transducer
something like the damped sinusoid shown in figure 3.11. The basic ringing
frequency of the vibration is the same as the resonant frequency determined
as indicated earlier by the thickness of the crystal. The severity of the damping
is determined by the damping incorporated in the transducer probe backing.
Thus the pulse width, or more correctly the pulse duration, is set by the degree
of damping.
CURRENTl
SPIKE
(a) L-.......;~_ _ _ _ _ _ _ _ _ __
CRYSTAL
STRAIN
or
VOLTAGE
t
(b)
Figure 3.11 (a) When a capacitor is discharged through the crystal, a spike of current
flows through the crystal. (b) As a result of the current spike, the crystal undergoes
damped oscillation or ringing across its thickness. Accompanying this vibratory strain
there is also a damped voltage oscillation across the crystal. The greater the damping
present the shorter is the duration of this ringing
(a)
(b) I
PULSE I
(a)
TOP VIEW
b
~
---------------------------Z
<>---- b 2/4 A - - - t >
(b)
(c)
Figure 3.13 (a) The front of a rectangular crystal of dimensions a x b. (b) The top
view of the approximate shape of the beam of ultrasound produced by such a rectangular
crystal, with Near Field and Far Field features . (c) The side view of the beam produced
by the rectangular crystal, showing a Near Field longer than that seen in top view.
There is therefore a span of the beam intermediate between the Near Field proper (that
shown in top view) and the Far Field proper (that shown in side view)
PLASTIC FACING
\ n CRYSTAL ELEMENTS
c, DA~:~K:
HOUSING
I ~CTRICAL
~~:,:::::::::::::::::::::::::=====~.I CONNECTIONS
ISOLATORS
Figure 3.14 The main features in a multi-element linear array transducer, incorporat-
ing the n crystal elements with their electrodes and electrical connections, the front
facings, the insulating isolators between the elements, the damping block and the
overall housing
figure 3.4. A new vital component in the array probe is the set of slices of
mechanical and electrical isolating material, cork or rubber, located between
each pair of crystals to minimise any mechanical or electrical coupling be-
tween the crystals .
Each crystal element has a much lower height (along the array) than
width and if operated alone would have a very short near field. Usually,
44 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
1fZl
21Zl
30
4fZl
V(
) '!YVAVEFRONT
) 'MOTION
5~
Figure 3.15 Electronic beam focussing, achieved by controlling the phase of the
pulsed excitation of the five elements acting as a group at a time
defined as the ratio of voltage (e) produced to acoustic pressure (p) applied
(equation 3.6)
S=e/p (3.6)
In practice the sensitivity depends on the material of the crystal, the use
of the crystal at resonance, the amount of damping, the use of quarter
wavelength matching and the electrical circuit (the amplifier) into which the
transducer is connected.
Thus lead zirconate titanate (PZT) is more sensitive than barium titanate
which is in turn more sensitive than quartz. Sensitivity is greatest at the half-
wavelength thickness resonant frequency, but the sensitivity is reduced when
more damping is associated with the probe. Quarter wavelength matching
optimises the transfer of acoustic pressure from the medium to the piezo-
electric element and hence improves sensitivity. Finally, electrical matching
into a high input impedance tuned amplifier ensures that the overall sensi-
tivity is maximised.
Note that the acoustic pressure causing the crystal to generate the voltage
is the instantaneous average pressure on the front face of the crystal. If the
crystal is small relative to the wavelength, this averaging is over a small
possible range of pressure. But if the crystal is large relative to the wave-
length, there may be a wide range of pressures involved in the averaging and
the orientation of crystal to ultrasound wave also affects the response. Note
that the best response is found when the plane longitudinal wave is per-
pendicularly incident on the front face. As the direction of approach of the
wave to the transducer face swings away from the perpendicular the re-
sponse falls off. Thus, in the situation that is assumed to approximately
pertain in diagnostic ultrasound, where the plane longitudinal wave travels
out from the generator probe and back to the receiver probe (often the same
probe as the generator probe) along the direction of the beam axis, the
optimum wave detection is achieved.
HIGH INTENSITY
ENSITY
~ t
START
Figure 3.16 The rise in temperature at a point in an absorbing medium, after the start
of ultrasound irradiation, at two different intensities
2AI
F=- (3.7)
c
for a perfectly reflecting surface (i.e. R = 1). Here A is the area of the beam
intercepted by the reflector, c is the speed of propagation in the liquid
medium before the reflector and I is the average intensity in the intercepted
part of the beam.
This force may be measured with a sensitive balance as shown in figure
3.17. The smaller the reflector surface intercepting the beam, the finer the
intensity measurement in the beam.
PROBE
UID MEDIUM
Figure 3.18 Different coloured rings, or other shaped regions, of the liquid crystals,
would denote areas of different intensities in the ultrasound beam traversing the crystals
The piezoelectric materials used in the transducers are very brittle. Therefore,
care must be taken not to subject the probes to impact forces, such as being
dropped on the floor. If the crystal is cracked the probe can be useless. The
metal electrodes on the crystals are not strongly bonded to the crystal ma-
terial and can be readily detached by scratching. Occasionally, the protective
plastic layer may also be removed by abrasion and scratching. Surface
scratches on this plastic layer affect the focussing and the matching proper-
ties of the layer. The front face of the probe should therefore be handled with
great care and when being cleaned should be washed and, if necessary, dried
very gently.
The housing of the probe is usually fairly robust, but the probe as a whole
should not be dropped as this may dislodge or crack the crystal inside.
Finally, the electrical connections to the crystal should be kept clean, free
of oil, coupling agent, grease and dust, since these could affect the electrical
matching to the pulse generator and receiver amplifier.
x
FIXED
TX PROBE
BASE
(a)
o 10mm
(b)
o 10mm
<I
TRANSDUCER
DIAMETER
Figure 3.20 Two possible relative intensity profiles across diameters of the ultrasound
beam, one (a) symmetrical and the second (b) quite asymmetrical
3.15 BIBLIOGRAPHY
Kremkau, F. W., Diagnostic Ultrasound: Physical Principles and Exercises, Grune &
Stratton, New York, 1980
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
Millner, R. (Ed.), Ultrasound Interaction in Biology and Medicine, Plenum Press, New
York, 1983
Rose, J. L. and Goldberg, B. B., Basic Physics in Diagnostic Ultrasound, John Wiley,
New York, 1979
de Vlieger, M., White, D. N. and McCready, V. R., Ultrasonics in Medicine, Excerpta
Medica, Amsterdam, 1974
de Vlieger, M. et al. (Eds), Handhook of Clinical Ultrasound, John Wiley, New York,
1978
Wells, P. N. T., Biomedical Ultrasonics, Academic Press, London, 1977
Woodcock, J. P., Ultrasonics, Adam Hilger Ltd, Bristol, 1979
Annual Reviews
figure 4.1. The transceiver probe (probe capable of transmitting and re-
ceiving) sends out a pulse of ultrasound and then remains quiescent for a
period of time. The pulse of ultrasound travels through the medium at the
speed of propagation of sound in the medium. After some distance, it
encounters a reflecting boundary. At the boundary, the incident pulsed
wave is partitioned into reflected and transmitted components. The re-
flected component travels back towards the probe at the speed of propaga-
(c) ]
(d)
Figure 4.1 Ultrasound pulse echo formation. (a) A pulse of ultrasound is transmitted
from the transducer towards the reflector, L m away. (b) The pulse reaches the re-
flector Lie s later and some of the pulse is reflected back towards the transducer while
some is transmitted into the next medium (c). (d) After a subsequent Lie s the reflected
pulse arrives back at the transducer as an echo. Note that e mls is the speed of
propagation in the medium between the probe and the reflector
tion of ultrasound in the medium. At some time later this reflected pulse
reaches the transceiver as an echo and is detected by the transceiver. By
measuring the time (LIt) taken for the echo to return and knowing the speed
of propagation (c) in the medium, the depth (L) of the boundary producing
the echo may be calculated by equation (4.1)
cLlt
L=- (4.1)
2
If the path of the ultrasound wave includes segments with different speeds of
propagation, use of the pulse echo equation of the previous section to calcu-
late the depth of reflection requires knowledge of the average speed of
propagation. Consider the case illustrated in figure 4.2, of two tissue layers
Figure 4.2 Pulse echo propagation across two different media of different thicknesses,
L and L z ' and with different speeds of propagation. (" j and ("2
j
with speeds c \ and c 2 • The time delay ,1 t for the echo to return from boundary
B, is the time taken to travel twice across both layers (equation 4.2)
2L\ 2L2
=-+-- (4.2)
c\ C2
This is the time taken to travel twice the total depth at the average speed Cay
(equation 4.3)
2(L\ + L2 )
,1/=----- (4.3)
Cay
54 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
(4.4)
It must not be taken to be the arithmetic mean of the two speeds. In practice
the average speed used to compute depths and thicknesses of tissues is
pragmatically taken as the value that minimises the errors in these
calculations. Thus for human soft tissues in vivo, the accepted or standard
average propagation speed is 1540 m/s. In the situation where the foetal skull
bone is interposed in the beam the average speed used is 1600 m/s.
Thus in the calculation of depth in a multi-layered slice of soft tissue the
pulse-echo equation becomes
(4.5)
VOLTAGE t
AMPLITUDE I
Figure 4.3 A typical A-mode display, showing a train of echo pulses. displayed each
in turn further to the right (i.e. deeper) from the initial transmission pulse which
corresponds to the skin surface
A-MODE SCANNING INSTRUMENTS 55
be readily converted, by appropriate scaling, to a depth axis. Thus most
usually the A-mode display is considered a plot of echo amplitude versus
depth of the reflecting structure below the point of initial pulse transmission
(often the surface or skin).
MASTER
TIMER
PULSE (p.r f.)
TIME GAIN
COMPENSATION
DISPLAY
T<>-+------'
L-----f_----!-<>Y
(a) Probe
The probe houses the piezoelectric crystal and all of its important aspects
were discussed in the previous chapter. In this instrument it functions both
as a transmitter and a receiver of ultrasound. i.e. it is a transceiver.
56 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
The nature of the electrical pulse generator was also described in the previous
chapter. Its task is to provide an electrical current pulse or hammer-blow to
the transducer crystal. It produces this electrical stimulus when demanded
by the pulse repetition frequency controller, the master timer.
The amplifier is an electronic component which takes into its input the
voltages produced on the transducer crystal by ultrasound echoes, and sends
out from its output larger, i.e. amplified, versions of these voltage pulses. It
should amplify each voltage linearly, i.e. all voltages multiplied by the same
factor.
In many instruments this amplifier is tuned to preferentially amplify the
main operating frequency (occasionally termed the rf or radio frequency)
thereby improving the signal amplification in comparison with that of any
extraneous or noise voltages. However, the multiplying factor or amplifica-
tion factor, is varied during the receiving phase of the transceiver by the time
gain compensation component in the A-mode instrument.
Time Gain Compensation (TGC) is also referred to as Swept Gain. The idea
behind this element in the instrument is the fact that the deeper the echoing
structures, i.e. the further away from the probe is the echo-producing
boundary, the more attenuation does the echo from that boundary ex-
perience before it is received at the probe. Thus, two similar boundaries, one
positioned close to the probe and the other positioned far from the probe,
would produce widely different echo strengths. The more remote boundary
would produce a very weak echo compared with that from the nearer
boundary. One might deduce that there are significant differences between
the two boundaries, whereas they are in fact similar. In order to try to display
the two echo strengths as being comparable, as should happen from the
nature of the boundaries, time gain compensation is introduced. This com-
pensation consists of amplifying the deeper (later) echo signal voltages more
than the closer (earlier) echo signals. Thus, the later an echo arrives, the
more gain it experiences in the receiver amplifier. The so-called Time Gain
Compensation (TGC) curve, illustrated in figure 4.5 is a graph of the ampli-
fication factor plotted against the time delay after the initial pulse is trans-
mitted. Since from the basic principle of echo-ranging, these time delays are
directly proportional to depth, this graph may also be regarded as a graph of
A-MODE SCANNING INSTRUMENTS 57
GAIN
(dB)
FINAL
~----------------------r----------
GAIN
IN ITIA~r---_______ SLOPE ~
GAIN DELAY--<>
DEPTH(m)
or TIME DELAY
Figure 4.5 A simple time gain compensation (TGC) function, showing the four
parameters which may be varied, the initial gain, the delay, the slope and the final gain
the gain or amplification factor plotted against the depth of the echoing
surface or reflectoL
Usually four separate parameters of the TGC curve may be varied. Firstly
there is the initial gain, the amount of amplification applied to the very
earliest (superficial) echoes. Then there is the delay, the depth below the
probe from within which echo signals receive the same amplification as the
very earliest echoes. This would be the superficial layer of tissues of least
diagnostic interest. Thirdly, there is the slope or the TGC proper, during
which range of depth a steadily increasing amplification factor is applied. The
slope of this part of the graph is chosen to compensate for the attenuation
factor in the tissue in question. Finally, there is the final gain, usually the
maximum gain attainable by the amplifier, which is applied to the latest
(most remote) echo signals. Usually. the echoes from the tissues of greatest
interest are positioned in the slope region of the curve.
In most instruments. these four parameters can be varied to suit a particu-
lar tissue or region of the body and to match the attenuation at the operating
frequency in those tissues.
In some applications the slope portion of the curve may be segmented into
slabs with different slopes. in order to compensate for layered tissues with
distinctly different attenuation properties.
In other applications. particularly in studies of heart valves. a higher step
of amplification may be applied to a specific layer of tissues within the slope.
in order to accentuate the echoes from reflectors within that layeL
(e) Demodulator
The action of the demodulator is shown in figure 4.6. Each damped alternat-
58 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
t
(a)
(b)
t
(c)
t
Figure 4.6 The processing steps experienced by a received radio frequency (rt) echo
signal (a), in an A-mode scanner. (b) Full-wave rectification and (c) demodulation or
envelope extraction
ing (rf) echo pulse is first rectified. Next a voltage output is developed which
follows the amplitudes or the smoothed envelope of the half cycles of the
rectified pulse. The resulting pulse shape represents the amplitude of the
original pulse at each moment during the pulse. The amplitude pulse is
then displayed to form the amplitude on the A-mode display.
(t) Display
The normal type of display for these amplitude (or A-mode) signals emanat-
ing from the demodulator is a cathode-ray oscilloscope (eRO) (see Ap-
pendices G and H). The sweep or horizontal deflection (X axis) of the
oscilloscope display is initiated or triggered by a pulse from the pulse
repetition frequency master controller and the amplitude signals from the
demodulator are fed to the vertical deflection or Y plates of the oscilloscope.
The time base of the oscilloscope or the rate of sweep of the electron beam
across the X axis is arranged so that distance across the screen is a known
factor ( x 0.25, x 0.5, xl, x 2) of the depth in the medium or tissue. In this
way, a display such as is shown in figure 4.3 is presented.
The typical A-mode display, therefore, consists of a train of echo pulses
arranged to the right of the transmission pulse artifact and separated by
distances proportional to the depths of the reflecting structures. The ampli-
tudes of the echo pulses depend on the reflection coefficient and the angle of
A-MODE SCANNING INSTRUMENTS 59
incidence at the reflecting surface, on the attenuation in the tissues and on the
TGC used.
In order to produce a stationary or visually persistent image on the
oscilloscope screen, it is necessary that the train of echo signals be displayed
at least 30 times each second, that is above the critical flicker fusion fre-
quency for the human eye. The number of times per second that it is in fact
presented is also the number of times per second that an ultrasound pulse is
transmitted. This is determined by the pulse repetition frequency master
timer, the system clock.
In many units it is possible to vary the amplitude of the current pulse used to
excite the transducer and thereby to control the intensity of the transmitted
ultrasound pulse. The knob or switch which performs this electronic attenu-
ating function is often calibrated in dB units. If the amount of electronic
attenuation is reduced, not only is higher intensity ultrasound transmitted,
but the echoes from weakly-reflecting structures may also be enhanced.
Thus, the amplitude detail of the A-mode display can be modified with
this control.
60 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
Some A-scan machines are equipped with a suppressor (reject) control. This
control allows the operator to eliminate or reject low amplitude echo signals
and noise signals of amplitude less than a certain set minimum or threshold
level. This control can help to produce a clean A-mode display.
Some machines are also equipped with a limiter or peak-clipping control
which sets the value of the maximum echo amplitude which is displayed. The
limiter control sets the echo amplitude adequate to saturate the display.
Figure 4.7 illustrates these parameters.
The range of echo signal amplitudes on the display between the minimum,
which may be set by the suppressor control, and the maximum which may be
set by the limiter control or by the characteristics of the amplifiers used in
the system, is called the dynamic range of the display. Echo signal amplitudes
which fall within the dynamic range are displayed on the screen with dis-
tinguishably different amplitudes. Echo signals greater than the maximum
of the dynamic range may not be distinguished from each other because they
simply saturate the display, i.e. they are all displayed as maximum deflections
on the display. Echo signals of amplitudes below the minimum of the dynamic
range are not displayed at all. Control of the suppressor and limiter, there-
fore, help to determine the dynamic range, i.e. the range or span of echo
strength which can be distinguishably displayed on the screen.
Usually the dynamic range is measured as the ratio of the maximum dis-
playable signal amplitude to the minimum amplitude. Alternatively it can
be expressed in dB, the logarithmic version of this ratio.
A-mode instruments are often equipped with a knob to control the pulse
A-MODE SCANNING INSTRUMENTS 61
(a)
(b)
(c)
Figure 4.7 A train of echo signals shown in (a) may be modified by increasing the
level of suppression as in (b), thereby eliminating the low amplitude signals including
electronic noise from the display. The echo train may also be modified by changing the
limiter level or level at which peak-clipping occurs as in (c). Both of these controls
change the dynamic range of the display
repetion frequency (prf). This control sets the frequency of the master timer
pulse generator. This, in turn, sets the repetition frequency for the complete
operation cycle of the instrument comprising transmission of pulse, re-
ceiving of echo pulses and their display. In practice, increasing the prf
produces a brighter display on the screen because of more frequent renewal
of the registration on the oscilloscope screen. But, there is an upper limit to
the prf as mentioned earlier and for typical depths in the human body, this
upper limit is something in the vicinity of 2500 Hz.
(f) Demodulator
(a)
(b)
Figure 4.8 Increasing the time constant of the demodulator causes smoothing in (b)
of the sharp (very fast) components of the echo signal in (a)
The time base setting of the oscilloscope is arranged so that a distance along
the oscilloscope sweep is proportional to depth in tissue. The relationship
between the two involves the average propagation speed of ultrasound in
tissue. The assumed average propagation speed for ultrasound travelling
through soft tissues is 1540 m/s. However, for some tissues, for instance in
biparietal diameter measurement in the foetus, where there is some bone in the
pathway, a higher average propagation speed of 1600 m/s is more appropriate.
For some tissues with a high fat content, a propagation speed below 1500 m/s
is more appropriate. Consequently some machines are equipped with a
control to enable the assumed average propagation speed to be varied as
required. In most normal operations, however, this is not a control which is
tampered with.
A-MODE SCANNING INSTRUMENTS 63
(h) Oscilloscope Controls
The A-mode instrument is also equipped with many of the normal knobs
that control the oscilloscope display. One of these is the brilliance or bright-
ness control which sets the brightness or luminance of the oscilloscope trace.
Occasionally this needs to be increased or decreased, in particular when
photography is required.
Another control is the focussing control which ensures that the electron
beam in the oscilloscope is focussed on the screen to produce a sharp thin
trace.
Two further controls are also occasionally available, position controls,
which enable the trace of the oscilloscope to be positioned as required on the
screen. These controls can move the display in the vertical and horizontal
directions.
DISPLAYS
(a)
TRANSDUCER
REFLECTORS
~ • •
(b) b
Figure 4.9 Depth or axial resolution may be assessed by placing two identical re-
flectors side by side along the axis of the beam. The A-mode display is then inspected
as they are brought closer together. The minimum separation between them which
allows the two echo signals to be distinguished is a measure of the axial resolution. In
display (a) the signals are resolved while in (b) they are not
RESOLUTION
(mm)
2 3 4 567 10 20 f(MHz)
Figure 4.10 The axial resolution in mm as a function of the operating frequency in
MHz, for optimally damped transducers
A-MODE SCANNING INSTRUMENTS 65
demodulation time constant, all can modify the appearance of the displayed
pulses. Hence the axial resolution achieved in any situation depends strongly
on the machine settings chosen.
The question of lateral resolution, the ability to distinguish echoes from
two neighbouring structures close to each other at the same depth, is not so
important in A-mode scanning. But, it will be considered in detail in relation
to B-mode two-dimensional scanning in chapter 6.
4.9 SENSITIVITY
4.10 ARTIFACTS
I STRONG DISPLAY
REFLECTOR
Figure 4.11 The production of reverberations between the probe and a strong re-
flector. causing artifactual reverberant echo signals on the A-mode disnlav
66 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
echo, which returns at the appropriate time delay. However, some of this
echo is reflected from the transducer face, travels out to the reflector to be
reflected again. This returns to the transceiver and is displayed twice as deep
as the true echo. Indeed, a number of such successive spurious echoes or
reverberations may be strong enough to be displayed if the medium is not
highly attenuating. From the appearance of the display, one would falsely
picture a layered medium with each layer of the same thickness. The most
obvious mark of reverberation is the equal distance between the reverbera-
tion 'echo' signals, and this feature allows one to recognise this artifact.
Another type of artifact is the multiple path artifact. In viewing the A-mode
display one assumes that the ultrasound beam travels in a straight line. One
interprets the display by correlating the echo signals with structures along
that assumed straight-line path. However, occasionally the ultrasound could
travel by more circuitous routes such as illustrated in figure 4.12. Here the
transmitted pulse travels out and is reflected at an angle from surface A. The
--t>' (L,+LAi--
2
DISPLAY
Figure 4.12 A multiple path artifact can occur when the echo returns to the probe by a
circuitous path, while the A-mode display assumes that the echo arises along the beam
axis and returns along the same path. An echo signal is displayed at a depth which does
not correspond to any reflector
t
ECHO
t\
DISPLAY
Figure 4.13 Refraction at boundary A, causes the beam to bend from the original axis.
The assumption of the A-mode instrument that straight-line propagation occurs is
violated, and the echo which returns from boundary B is then erroneously located by
the instrument. It is wrongly taken to be a distance Ll + L2 along the original axis
actual propagation speeds are greater than the average, then the echo pulses
are displayed closer to the surface (shallower) than they ought to be, and the
reverse occurs if the actual propagation speeds are less than the average.
Shadowing is a phenomenon which can cause echoes from certain deep
structures to be negligibly small or absent from the display. Such shadowing,
illustrated in figure 4.14, can happen if there is a very strong reflector, such
as a gas or a hard tissue boundary early in the beam. These very strong
reflectors allow very little ultrasound to penetrate to deeper structures, with
the result that these latter structures do not produce echo signals strong
enough to register on the display. Another mechanism for shadowing is a
highly attenuating medium in the early part of the path of the beam. This
allows negligible amounts of ultrasound to penetrate to deeper structures,
with the result that appreciable echoes are not obtained from such structures.
REFLECTORS
PROBE \B\
/' DISPLAY
VERY STRONG
REFLECTOR
Figure 4.14 A strong reflector (or a strong attenuator) located early in the beam path
reduces the intensity of the beam such that deeper reflectors fail to produce echo signals
strong enough to register on the display. Thus reflectors Band C are shadowed by
reflector A
The finite width of the ultrasound beam which as will be seen later, is the
main determinant of lateral resolution in the B-mode instrument, also re-
sults in structures, as shown in figure 4.15, which are well away from the
68 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
ECHOES
PROBE
~ ~ AXD D~]1\
I I
A D
DISPLAY
OFF-AXIS
REFLECTORS
Figure 4.15 Off-axis reflectors which are still at the edges of the beam, produce echoes
which register on the A-mode display and are assumed to be on the axis. Also two
off-axis reflectors at the same range as C and D, are registered as one echo signal on the
display and the erroneous assumption of a single reflector at that range made
axis of the beam, producing echoes which are displayed and assumed to be
on the axis.
Poor adjustment of the controls of the instrument can accentuate many of
these artifacts. Careful tuning, especially of the receiver, i.e. the TGC and
the suppressor, minimise these effects. But some of these artifacts are in-
herent in the technique and often have to be accepted in the A-mode display.
They may usually be reduced in B-mode imaging as will be discussed in
chapter 6.
In practice, the transducer probe is placed on the skin of the patient with the
ultrasound beam directed towards the tissues of interest. For contact scanning
to be effective, an acoustic coupling agent is needed between the probe
surface and the skin. This coupling is necessary to eliminate all air from that
region. Various water based gels and vegetable oils, such as olive oil, are used
for this purpose. Most of these agents have acoustic properties similar to the
soft tissues of the body. Furthermore they adapt to the shape of the probe
and that of the body surface as shown in figure 4.16. In this way, air bubbles
are excluded and the maximum transfer of ultrasound into and out of the
body is achieved quite simply. It is desirable that these coupling agents
should not be very fluid so that they remain in position as much as possible
for the duration of an examination. Also one needs to use only a small
amount of the couplant so that the temperature of the superficial tissues is
not lowered appreciably below the normal level.
A-mode scanning was the earliest ultrasound technique developed for
A-MODE SCANNING INSTRUMENTS 69
AGENT
Figure 4.16 The action ofa coupling agent-an oil or a gel-is to provide an acoustic
pathway between the transducer face and the skin surface. It eliminates air bubbles and
adapts to the contours of the skin and the probe
Various aspects of the A-mode unit can be readily tested. Such tests should
be regularly carried out to ensure the consistency of the performance of the
70 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
instrument and the day-to-day reliability of any measurements made with it.
The various types of beam measurements described in chapter 3 are ap-
plicable to this instrument. But since this machine is based on the pulse-echo
principle, the determination of the iso-echo contours in the pulse-echo beam
is especially relevant. It checks the beam and the signal processing and
display of the system.
Iso-echo contour plots are lines connecting points in the beam from
which equally strong echo signals are received, when some standard re-
flector is moved around in the beam. In this case the ultrasound transmitting
probe acts as receiver in order to receive the echoes reflected from the
standard reflector. This is usually a spherical steel ball in a water bath. An
arrangement such as is schematically shown in figure 4.17, is used to derive
the data. When the data have been derived, iso-echo plots can be drawn as
z
y
x
FIXED
PROBE
LI U I D----..""
M DIUM
shown in figure 4.18. The result is a contour map of the beam on which the
contours connect points in the beam from which equal amplitude echoes are
received.
A simple test of dynamic range is to direct the beam vertically downwards
into a vessel with a flat horizontal sheet of metal on the bottom. The vessel
contains one of the solutions described in section 10.11, which has a speed
of propagation of 1540 m/s. The probe face is located 1 cm from the surface
of the metal sheet. The delay of the TGC is made longer than the width of
the display.
A-MODE SCANNING INSTRUMENTS 71
Figure 4.18A possible pattern of iso-echo contours in the beam of a probe. The
maximum echo amplitude is taken as the 0 dB reference
Figure 4.19 A simplified set of reverberation signals obtained from a shallow water
bath of fixed depth with a fiat base perpendicular to the beam
Regular repetition of this test on the same reflector set-up would allow
changes in system sensitivity to be noted. A reduction in sensitivity would
require a higher initial gain to just raise the fifth reverberation above the
baseline. It would also need a greater gain to saturate that reverberation
signal.
Because this medium has a speed of propagation of 1540 m/s each rever-
beration signal should appear on the display at 1 em intervals exactly.
Therefore the display, as shown in figure 4.19, is a test of the measurement
accuracy of the A-mode unit. In the same way the caliper accuracy may be
checked.
The axial resolution can best be measured with a target system such as the
AlUM (American Institute of Ultrasound in Medicine) target which is de-
scribed in detail in chapter 6. The portion of the target used to measure
axial resolution is the set of wires in the middle as are shown in figure 4.20.
The target is filled with a liquid solution with propagation speed 1540 m/s.
When the probe of the A-mode unit is moved as shown in figure 4.20, from
left to right, initially the wire reflectors are separated along the depth direc-
tion by a sufficient amount for the echo signals on the display to be dis-
tinguishable. But at some stage the depth separation is not enough to allow
72 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
the echo signals to be resolved. The smallest such separation between the
wires to allow resolution is the axial resolution.
-d-
il~:~··
2 .. ---..
1 (:.-.-..-\
Figure 4.20 A cross-section through the part of the American Institute of Ultrasound
in Medicine (AlUM) test object which may be used to measure the axial resolution.
The separations between the wires are given in mm and more than two of the wires may
be located within the beam at any position of the probe (see figure 6.16)
The first and major limitation of the A-mode technique is the fact that it
displays information about structures along a single line through the tissue,
or more accurately, about structures along the cylindrical path of the ultra-
sound beam. Essentially, it provides one-dimensional data. If information
about another path through the tissues is required, the transceiver probe
must be moved to interrogate the new region of tissue, but the display retains
no memory of the previously-examined tissue. The operator must retain this
memory and also must remember the movement and positions of the probe.
Another limitation of the A-mode system, particularly when permanent
records of the displays must be kept, is its difficulty with moving structures.
If the moving structures remain in the beam, they produce a display with a
constantly moving echo voltage pulse. If they occasionally move outside the
beam, then their appropriate echo voltage pulses are only occasionally
displayed.
These two limitations are solved respectively by the development of B-
mode scanning and M-mode scanning techniques. These topics will be
considered in chapters 6, 7 and 5, respectively.
A-MODE SCANNING INSTRUMENTS 73
4.15 BIBLIOGRAPHY
One of the drawbacks of A-mode scanning is the fact that it yields only crude
qualitative appreciation of the motion of structures. In order to overcome
this difficulty, in particular for applications dealing with rhythmically-
moving structures such as the heart and its valves, motion (M-), also called
time-position (T-P), mode scanning, has been developed.
After reading this chapter the student should be able to:
(a) describe the M-mode display;
(b) outline schematically the M-mode instrument and describe the role
and operation of each functional block in the unit;
(c) show the main ways in which permanent records of M-mode exam-
inations may be obtained;
(d) discuss the most likely artifacts which may be encountered in M-mode
scanning;
(e) describe how simple tests may be done to check the performance of the
instrument;
(f) outline broadly the areas of clinical application of this technique;
(g) discuss the limitations of M-mode scanning techniques.
.... -.
.-~------~--
. . - .... - -
-~------.------
- - -
- -
- -
... -.- - - - - - - - - - ... - --e
- 4- -
- ------
- - - -
- - - ... - - - -
-
...
..
..
!TIME
• - ... - - - - - - - - - -e- - - - •
----<>
DEPTH
Figure 5.1 An M-mode display is essentially a recording of the depth of all reflecting
structures at each successive instant during the examination. This M-mode display
shows one moving structure in the middle of the field and three stationary structures,
one at depth and two in the superficial region
MASTER
TIMER
PULSE fL (P. r. f.)
GENERATOR
~ PROBE~
~ L
~
RECEIVER
.......... TIME GAIN
-
AMPLIFIER CONTROL
t~
DEMODULATOR
, -- 1M
BRIGHT-UP
PULSE
GENERATOR
rL.JL
ZO
SLON SWEEP ~ Y T
SIGNAL
GENERATOR DISPLAY
Figure 5.2 A block diagram of an ultrasound M-mode scanner, showing the func-
tional components and the interconnections between them
(a)
(\ 0 f\ ~
(b) n n n rL
(c) eo- - - - - - - .... - - - - - - - - - -e- - - - - - - - - ..
(d) ~ ~ n L
Figure 5.3 The signal processing steps involved in converting the A-mode signal
shown at (a) into the line element of the M-mode display as shown at (c). At each
leading edge in (a) a brief voltage pulse of constant height and duration is generated
(b), and this in turn is used to bright-up (Z input) the oscilloscope display (c). Alter-
natively voltage pulses of heights proportional to the A-mode echo signal height may
be generated (d) and used to modulate the display brightness, thereby effecting a grey
scaling in this display
MOTION (M-) MODE SCANNING INSTRUMENTS 77
up , ihis reduces the amount of the reflector motion that is fitted into the
screen.
Clearly, a picture such as that shown in figure 5.1 may be used to calculate
the speed of a moving structure at any instant during the display period.
An alternative and more satisfactory way of achieving a time axis is to
dispense with the above additional time-base and to move a recording
photographic paper at a steady rate past the stationary baseline which con-
tains the pulse-echo information. In this way a chart recording may be made
of the moving structures under study, for as long as is required. Indeed
typically in a study of cardiac valve motion , the beam is caused to gradually
swing through a sector of the heart, producing a continuous recording of the
motions of each successive portion of the valves and walls. The instrumenta-
tion needed for such a technique is described in the next section.
In those instruments in which the amplitudes of the bright-up pulses are
proportional to the relevant echo amplitUde, the result of the above photo-
graphic recording technique is a grey scaled recording. The stronger echoes
produce a darker grey while weaker echoes yield a lighter grey on the black-
on-white display. An example of this latter is shown in figure 5.4.
- TIME
Figure 5.4 A grey-scaled M-mode recording of cardiac valve and wall motion . A
simultaneous ECG recording is located at the top of the trace
78 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
u.v. LIGHT
•t t t •
PAPER
MOVEMENT
r
I
CRO~:
TAKE-UP
SCREEN REEL
UNUSED
ROLL
LIGHT-TIGHT BOX
Figure 5.5 The main components in an ultraviolet chart recorder for registering
M-mode scan information
In these cases the movement of the paper is equivalent to the sweep of the
baseline on the screen in the system of figure 5.2. The paper speed may be
reduced or increased as required.
Some machines use photographic paper which must be developed in a
dark room, by conventional wet processing techniques (see chapter 9). The
advantage of the continuous chart recorder is that long periods of recording
can be used. For instance, if the heart is being examined, very many heart-
beats can be included in a single trace. In all of these techniques where heart
studies are involved, tracings of an electrocardiogram (ECG) lead and of the
MOTION (M-) MODE SCANNING INSTRUMENTS 79
5.5 ARTIFACTS
Since the M-mode instrument has very much in common with the A-mode
unit, all of the artifacts described in section 4.10 may also be encountered
when using the M-mode instrument in the clinical setting.
One further artifact may also be mentioned - that of the incomplete or
gapped trace. If the motion of the reflector under study is not along the
beam axis, it may not be in the beam or else it may present to the beam at an
oblique angle, for some of the time. The result is a time-position trace
which has gaps at those phases when the reflector is not returning an echo
strong enough to register.
All of the performance tests discussed in section 4.13 are relevant to the
M-mode instrument.
In addition the time scale needs to be checked and calibrated. A simple
way of doing so is to use a small vessel with a flexible rubber base as shown
in figure 5.6. The flexible base is vibrated in a sinusoidal manner with an
electromagnetic vibrator at a known frequency and a known amplitude. The
vessel is filled with a solution of propagation speed 1540 mls (see section
to.11). The probe is directed vertically downwards and an M-mode recording
made. The recording of the moving membrane should be sinusoidal and its
frequency and amplitude should correspond to that of the membrane. This
is a sample check of the time scale and the depth scale of the display.
The main uses of M-mode scanning are in the detection of the motion of
intracardiac structures (especially the heart valves) but also of the walls of
the heart. Various portions of all four heart valves may occasionally be
80 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
PROBE
L1Q ID
ME IU~
~FLEXIBLE
r-----r----'---'---l BASE
L.----L_-----1VI BRATOR
Figure 5.6 An experimental vessel with a flexible base, driven sinusoidally by an
electromagnetic vibrator, which may be utilised to check the depth scale and the time
scale of an M-mode instrument
detected with the technique, but the easiest to detect is the mitral valve. The
normal valve has a characteristic motion and departures from the normal
can be readily diagnosed.
As well as the movement of the valves, the detection of the movement of
the walls can give very useful information about the chamber sizes. The
size, thickness and movement of the interventricular septum may be as-
sessed. Pericardial effusion may be detected and quantified. The performance
of prosthetic cardiac valves may also be studied with the technique.
Other uses of M-mode ultrasound scanning techniques are the detection
of foetal heart movement in pregnancy, studies on the movement of blood-
vessel walls, such as the abdominal aorta, and also studies of the pulsations
due to blood movement within the brain.
5.9 BIBLIOGRAPHY
Benchimol, A., Non-invasive Techniques in Cardiology for the Nurse and Technician,
John Wiley, New York, 1978
Chang, S., Echocardiography: Techniques and Interpretation, 2nd edn, Lea & Febiger,
Philadelphia, 1981
Feigenbaum, H., Echocardiography, 3rd edn, Lea & Febiger, Philadelphia, 1981
Goldberg, B. B. (Ed.), Abdominal Grey Scale Ultrasonography, John Wiley, New York,
1977
Gosink, B. B. and Squire, L. F., Exercises in Diagnostic Radiology. 8: Diagnostic
Ultrasound, W. B. Saunders Co., Philadelphia, 1976
Kisslo, J. A. (Ed.), Two-dimensional Echocardiography, Churchill Livingstone, New
York,1980
Linhart, J. W. and Joyner, C. R., Diagnostic Echocardiography, C. V. Mosby Co., St
Louis, Mo, 1981
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
Metreweli, c., Practical Abdominal Ultrasound, Heinemann, London, 1978
Meyer, R. A., Pediatric Echocardiography, Lea & Febiger, Philadelphia, 1977
Miskovits, c., Echocardiography: A Manual for Nurses, Medical Examination Publish-
ing Co. Inc., Flushing, NY, 1977
Reneman, R. S. (Ed.), Cardiovascular Applications of Ultrasound, North-Holland Pub-
lishing Co., Amsterdam, 1974
Roelandt, J., Practical Echocardiography, Research Studies Press, Forest Grove, Or,
1977
Salcedo, E. E., Atlas of Echocardiography, W. B. Saunders Co., Philadelphia, 1978
Short, M. D. et at. (Eds), Physical Techniques in Cardiological Imaging, Adam Hilger
Ltd, Bristol, 1983
82 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
It was pointed out previously that one of the major drawbacks of the A-mode
scanning technique is the fact that it acquires information about only a single
line through the tissue at any particular position of the probe. The most
common method for overcoming this one-dimensionality is the B-mode
technique.
After reading this chapter the student should be able to:
(a) describe the salient features of a B-mode display;
(b) draw a block diagram of a basic instrument for obtaining B-mode
images;
(c) describe the operation of each component block in this instrument;
(d) justify the uses of linear, sector and compound scanning in con-
structing the B-mode display;
(e) outline the main conventions used to define and label B-mode images
of body tissues;
(f) describe the ways of obtaining bi-stable B-mode images;
(g) discuss the role of scan converters in obtaining images with ranges
of greys;
(h) describe in general terms, analogue scan converters;
(i) show how the scan converter fits into the block diagram of a B-mode
instrument to obtain grey scale images;
(j) broadly describe the operation of digital scan converters;
(k) discuss the functioning of the instrument controls, available to the
operator on B-mode instruments;
(I) define axial and lateral resolution in B-mode scanning, and discuss
the factors which affect them;
(m) describe the principal artifacts that can occur in B-mode imaging and
how they may be eliminated or their effects minimised;
(n) show in general terms how permanent photographic records of B-
mode images may be obtained;
(0) describe instrument performance tests for B-mode units;
(p) contrast the use of skin contact B-mode scanning with water-path
delay line B-mode scanning;
(q) critically review the application of static B-mode scanning in the
clinical setting.
84 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
DEPTH~
- WIDTH OF CROSS-SECTION
INTO
TISSUES
RECEIVER TIME
~PROBE
~O-oRDINATE
MEASURING
,
AMPLIFIER
DEMODULATOR I
GAIN
t--
SCHEME -!
PULSE
FORMER
~
DISPLAY
Z
T
X Yr
I
Figure 6.2 A block diagram of a basic B-mode scanning instrument, showing the
functional components in the system together with the interconnections between them
This device detects the position and orientation of the probe at all times and
this co-ordinate information is fed to the display oscilloscope in order to
generate the B-mode image. It causes the sweep baseline of the oscilloscope
display to be moved around the screen in step with the movements of the
probe. The direction of the baseline sweep on the screen is made to reproduce
the orientation of the probe and hence the orientation of the axis of the
ultrasound beam travelling out from the probe.
Consider the situation shown in figure 6.3, where the motion of the probe
is a simple linear translation. As the probe moves through successive loca-
tions, the baseline on the display also moves in step with the probe. When-
ever an echo is detected by the probe a bright spot is displayed on the screen.
Thus the B-mode display is a cross-sectional representation or image of the
structure under examination. The linear B-mode display can be fairly in-
complete because, as discussed in a previous chapter, echoes are received
only from structures positioned at or close to 90' to the interrogating
ultrasound beam. Structures and surfaces at more acute angles to the beam
do not produce appreciable echoes and so are not displayed.
Simple sectoring of the probe as shown in figure 6.4(b). can sometimes
86 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
SKIN ORGAN
~
PROBE]
MOTION
STRUCTURE
IMAGED
•I·
,.
~
~
• 2-D B-MODE
DISPLAY
Figure 6.3 The production of a linear B-mode image involves slowly moving the probe
in a straight line over the skin. The resulting display of a complex structure is in-
complete
•
1- - - - ,- - -; ..
~
i I
i
i
~__- -_ -:.' 1- -
L ___
- :
i I
1 1
1
(a)
, \
,, ,\
,
\'v' , / \
I i - - ,
, \
I L __ J \
I \ \
\
/ \
\
(b)
I / \ \
/ \
,r---, ---,r--'\
,'............ I,: 1\ ,.'
, )~ I , i \ t-:!' _~
~ \.-7 .\')r- __ r ...... \
x.......)'
I / "... ....... ./ ____ I
,...... I ....... I I I \
(....f I..... L - - _. I \ .. " \ I I \ • J.
I -, I I / 1 1,',\ -;' \ i r-- ~
l
I
I I , I I " ~/ ~- - -, \_ ....... \
I I 1 1 / I I /\ ~- - - J \ \
/ I iii t\ 1 \
/ ./ I /
I \
(c) / !/ I I \ : .. \
Figure 6.4 The main types of probe motion used in ultrasound scanning. (a) Linear;
(b) angular rotation or sectoring; (c) a combination oflinear translation in two directions
and sectoring, the so-called compound scanning motion
STATIC B-MODE INSTRUMENTS 87
improve the image achieved but in most cases it suffers from the same
drawback as the linear type of movement.
In most B-mode instruments, both the linear and sectoring movements
of the probe are combined or compounded as shown in figure 6.4(c). In this
case, a much more complete and identifiable image of the organ of interest
can be achieved as in figure 6.5.
,.
••• ..• .-•
•
•• •
• •.,
•••
2-D B-MODE
e,... DISPLAY
Figure 6.S The result of compound scanning action is a more complete B-mode image
of a complex structure
(a)
(b)
Figure 6.6 The two alternative probe co-ordinate measurement systems used in
ultrasound B-mode scanners. (a) A Cartesian co-ordinate system; (b) a polar co-
ordinate scheme
88 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
Because the image of a cross-section or slice through the tissue may be dis-
played on the screen right to left or upside down, it is necessary for the sake
of clarity, to adopt certain agreed conventions for the image presentation.
Uniform conventions allow ready comparison among images from different
centres and different machines. Careful labelling of images is also an essen-
tial step.
For most studies the patient position is supine and the probe is in contact
STATIC 8-MODE INSTRUMENTS 89
with the front (upper surface) of the patient. Occasionally the patient is
prone or even propped in various other positions. This information is im-
portant in interpreting images and should be inscribed on the image.
Images of transverse planes, i.e. planes running from left to right and front
to back of the patient, are presented as if viewed from the patient's feet.
Thus such a view of a supine patient has the patient's front on top, back on
bottom, left on right and right on left. The location of the transverse section
along the length of the patient must be specified in the labelling. Horizontal
distances in centimetres cephaled ( + ) or caudad ( - ) relative to anatomical
landmarks indicated in figure 6.7, must be specified. The landmarks used are
the symphysis pubis (SP), umbilicus (U), xiphoid process (X) and supra-
sternal notch (SN). If the plane of the transverse section is angled, the angle
towards the head or towards the feet should be specified on the image.
Images on longitudinal (sagittal) cross-sections, i.e. planes running from
front to back and from head to foot of the patient, are presented with the
patient's feet to the right of the display. In a supine patient therefore the
image has the patient's head to the left, feet to the right, front to the top and
back to the bottom. The actual longitudinal plane of the image is labelled
with the number of centimetres horizontally to the right (R or +) or to the
...IX
I
Figure 6.7 The locations ofthe main anatomical landmarks on the trunk of the patient,
as used for longitudinal and transverse sectional images
90 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
The most basic B-mode displays are so-called bistable displays. The display
modality is a storage oscilloscope or a long persistence oscilloscope. In
particular with the storage oscilloscope, it is not possible to vary the bright-
ness of the bright spots stored on the display face. This basic feature is the
reason for the name 'bistable'. If a signal is strong enough to produce a
bright spot on the display, a bright spot of a fixed intensity is produced. If the
signal is not strong enough to produce a bright spot then the display has a
blank and is black at that point. An example of such a bistable display or
image is shown in figure 6.8.
In determining what signal strength will produce a bright spot on the
display, not only are the reflection coefficients in the tissues important but
also the intensity of the beam of ultrasound being transmitted, and also the
sensitivity and suppressor settings of the receiver. In practice, the receiver
settings are arranged so that only the strongest echo signals, i.e. those re-
ceived from plane specular reflectors, are displayed. In general, such specular
reflection is achieved mostly from the walls of the various organs in the body
and therefore the bistable display tends to be an image of the outlines of the
organs together with any strongly-reflecting blood vessels and other ducts in
the interior of the organ. The parenchyma of tissues tends not to be imaged.
By manipulating the receiver parameters, and especially by increasing the
gain or lowering the suppression level, succeedingly weaker signals can be
STATIC 8-MODE INSTRUMENTS 91
(a) __....foi
(h)
Figure 6.8 (a) A bistable image of the right kidney and a portion of the liver and for
comparison a more complete grey-scale image of the same section through the tissues,
shown in (b)
92 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
displayed and still more of the organ interior represented in the image.
However on the display, such weaker reflecting structures are then rep-
resented by spots as bright as more strongly reflecting organ walls. To
overcome this difficulty various efforts have been made to produce grey-scale
displays in order to represent the different echo strengths on the image as a
range of greys between black and white.
The basic idea behind the grey-scale display is the assignment of a grey level
to each echo signal amplitude as shown in figure 6.9. Thus, the stronger the
echo signal amplitude, the brighter the related spot on the display. In some
cases the reverse type of display, a negative image, is used, in which the
stronger echo amplitudes produce a darker spot, or rather a less bright spot
on the display. Thus, the final display can be white on a dark background or
else dark on a white background (negative).
One method of achieving such a grey-scale display is the use of time-
exposure photography during the image acquisition, in conjunction with a
long persistence oscilloscope display. The stronger echo signals produce a
brighter spot and a longer persistence of the bright spot on the screen than
the weak echo signals. The registration of these bright spots on the photo-
graphic film consequently reproduces a scale of greys depending upon the
brightness and time persistence of the oscilloscope image. Since the photo-
graphic exposure depends on the time of exposure, this grey-scale image is
very strongly dependent on the time taken to acquire the image and on the
rate of scanning movement of the probe over the skin. A steady rate of
WHITE 9
8
GREY
LEVELS ~
5
4
3
2
BLACK 10L--.l..--6.1..--.l..--12L--L--18L--L...-
24L.........J'----
ECHO AMPLITUDE (dB)
Figure 6.9 The assignment of shades of grey to the range of echo amplitudes, as
achieved by the scan converterjTV monitor combination. For example echo amplitudes
between 6 and 9 dB are assigned in this case to the third grey level above the black
STATIC 8-MODE INSTRUMENTS 93
movement, uniform from day to day, is needed to achieve reproducible
Images.
The mostly widely used means of achieving a grey-scale display is the use
of a scan converter in conjunction with a closed-circuit television monitor
(see Appendices I, J, K and L). A schematic diagram of a B-mode imaging
unit incorporating these features is shown in figure 6.10. The scan converter
tube is capable of storing an intermediate, latent image containing a contrast
range which in turn is determined by the range of echo signal strengths used
to construct the image in the first place. The link-up with the television
monitor allows this stored image to be continuously examined and displayed
on the television screen with all the contrast maintained. Permanent records
can be obtained by use of a photographic technique from the television
screen.
Thus, the scan converter functions in two modes. First, its storage screen
can be written all in order to store the two spatial dimensions and one
brightness dimension of the image information. Secondly, it can be interro-
gated in order to display the stored image on the television monitor. In
normal use, the scan converter is automatically switched to the store mode
PULSE MASTER
~
GENERATOR TIMER
0
RECEIVER
~PROBE
(with lG.q
COORDINATE AMPLIFIER A-MODE
MEASURING DISPLAY f---a-
SYSTEM t
/DEMODULATOR /
l -"
SCAN
CONVERTER
,
C)
B-MODE
TV
DISPLAY
Figure 6.10 A block diagram of a 8-mode instrument for producing grey-scale images.
It differs from the basic system of figure 6.2 in having a scan converter and a TV display
instead of the oscilloscope display
94 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
when the ultrasound probe is being scanned over the tissues. Then when the
probe motion is stopped, the system reverts to the read and display mode.
Manual switching into either of these modes is also possible. Also , it is
usual to have the capability to manually switch either to the black on white
display or to the white on black display . Figure 6.11 displays a white on
black and a black on white image of the same tissue section as obtained
from an analogue instrument.
(a)
( b)
Figure 6.11 Two images of the same tissue cross-section , (a) white image on a black
background and (b) black information on a white background
STATIC B-MODE INSTRUMENTS 95
6.7 DIGITAL GREY-SCALE DISPLAYS
SCAN
PLANE
IMAGE
Figure 6.12 The orderly mapping of elements of the scan plane through the tissues
on to the successive computer memory locations and the subsequent mapping of these
memory locations on to the picture elements (pixels) of the image or display, as achieved
by a digital scan converter. The overall effect is the orderly mapping of the elements of
the scan plane on to the pixels of the image
signal strength for the image of each portion of the scan plane is digitised or
converted into a number. Then, when the system is in the read or display
mode, the number stored in each memory location is used to determine the
grey level of the display on a television monitor for that particular pixel or
picture element location. In this way, the image is stored as a matrix (128 x
128,256 x 256 or 512 x 512) of numbers in the memory of the computer and
it may be rapidly read and displayed as desired.
This mode of storage is more reliable, more reproducible, and less subject
to difficulty with noise in the system than the analogue method, and is
96 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
coming into more use in the present period. It also opens up the possibility
of using more elaborate computer techniques for analysing and manipulating
the images .
The number of pixels used is a measure of the spatial detail or resolution
that can be achieved on the display. For a given field of view or area of cross-
section to be displayed , the more pixels in each dimension the finer the
details that can be distinguished on the display. The larger the pixels the
blockier the image presented. Figure 6.13 is an example of an image obtained
with a B-mode unit with a digital scan converter. On close examination the
pixels may be seen in some parts of the image.
Figure 6.13 A sectional image of the liver and right kidney obtained from a digital
scan converter
Practically all of the controls which are available on the A-mode unit, are
also used on the B-mode instrument. Thus the transmission pulse can be
electronically attenuated; the appropriate frequency tuning must be used to
suit the transducer ; the Time Gain Compensation must be set to suit the
tissues being examined; the suppressor and the limiter must be arranged to
set the appropriate dynamic range and the oscilloscope settings or the
STATIC 8-MODE INSTRUMENTS 97
television monitor settings must be arranged to achieve an acceptable
displayed image.
A most important variable in deriving a B-mode image is the time taken to
build up the image and also the rate of image build-up. Since this is achieved
by manually moving the probe, there is a certain amount of. subjective
variability involved. Furthermore, if the rate of image build-up is slow, all
of the other controls must be set to suit. Conversely, if the rate of probe
movement is high, different settings of the machine controls must be used.
Another variable which is usually available on the B-mode unit is a scale
factor. One can choose to display an image which is lifesixe (x 1), some
fraction thereof (x 0.5, x 0.2, etc.) or larger than lifesize (x 2, etc.).
Other controls which must be available for B-mode scanning are a switch
to erase the stored image whether it be a bistable display or a scan converter
grey-scale display, and also a means of taking a photograph of the image.
The camera controls, shutter speed, diaphragm setting and distance to screen
must be optimised, bearing in mind the brightness and contrast of the
image as well as the type of film used (see chapter 9).
diameter of any desired size may be chosen. But at any given frequency, the
length of the near field varies as the square of that diameter. Also, the angle
of divergence in the far field increases inversely as the diameter. So if a small
~- I
f+- - --+1--.--
-
(a)
B-MODE DISPLAY
~tJ- ,
\\ /
- -,1-' - --
'-!....WIRE;1
! \REFLECTORS B-MODE DISPLAY
(b) I '.
Figure 6.14 The lateral resolution of the B-mode scanner may be assessed by utilising
an array of wire reflectors, suspended in a medium with speed of propagation of 1540
m/s. The wires have successively smaller separations. When scanned the display consists
of a set of short lines, each representing one of the wires. When neighbouring lines
abut, lateral resolution is lost. An unfocussed beam as in (a) has poorer lateral
resolution than the focussed beam in (b) has at the focus
diameter is chosen, the cylindrical near field is very short and will not reach
to the depths of interest in the tissues. Depth information and beam direction-
ality at depth would therefore be sacrificed for the better lateral resolution
close to the probe.
A narrow beam with long near field can be achieved at higher frequencies
as discussed in chapter 3. Therefore, if the higher attenuation experienced in
tissues at higher frequencies can be compensated for, better lateral resolution
is achieved and depth directionality is maintained by choosing to scan at
higher frequency with a small diameter probe.
In practice, while it is possible to directly relate lateral resolution to the
frequency, the lateral resolution is some 5 or more times worse than the axial
resolution at the same frequency (see figure 4.1 0).
In all such cases the divergence of the beam in the far field, producing as it
does a wider beam, causes a degradation of lateral resolution. This degrada-
tion becomes progressive with distance into the far field.
STATIC 8-MODE INSTRUMENTS 99
Clearly, the lateral resolution in the near field can be improved if the beam
is focussed as indicated in figure 6.14(b). Effectively, focussing narrows the
beam and has the dual effect of improving the resolution and producing the
more accurate image of the small reflectors as well. The higher intensity at
the focus produces stronger echoes from any reflector located there. Hence,
small reflectors are better highlighted, while small spaces also are imaged
correctly. Focussing is also more effective at higher frequencies, so that the
lateral resolution at the focus improves as the frequency increases. It must be
remembered however that the lateral resolution is very dependent on where
along the axis of the beam one is concerned with. It is best in the focal
region, it is worse closer to the probe and it degrades progressively farther
away from the probe. The more extreme the focussing, the better the lateral
resolution in the focal region, but the worse it is closer to and further from
the transducer face.
6.10 ARTIFACTS
(a) (d)
(b) (e)
(c)
(0
Figure 6.15 The appearance of certain artifacts in B-mode images. (a) The repetitive
parallel lines of reverberation, due to air at the junction of a water bath and the skin.
(b) The blank linear shadow posterior to a strongly-reflecting stone in the gall bladder.
To the right of the shadow there is enhancement of the image due to the relatively
smaller amount of attenuation in the liquid-filled gall bladder. (c) Most of the right half
of the image is shadowed by gas in the bowel. (d), (e) and (f) illustrate the effects of
inappropriate setting of the TGC. In (d) it is properly set, while in (e) there is excessive
anterior compensation and in (f) there is inadequate posterior compensation for the
given longitudinal section through the liver
STATIC B-MODE INSTRUMENTS 101
echo signals from some of the deeper tissues are over-compensated by the
TGC system.
Unavoidable artifacts also occur in B-mode images due to the fact that the
beam of ultrasound has a finite width and interrogates a volume of tissues,
but displays the image along a straight line. The B-mode system concentrates
the echo information from each circular cross-section of the beam into a
point on the axis of the beam. As was discussed in relation to lateral resolu-
tion, any structures within the beam at the same distance from the probe are
not distinguished from each other. This results in smoothing of the features
of the image, small reflectors are made larger and small regions empty of
reflectors are filled-in on the image.
If the TGC variables are incorrectly set, artifacts can also appear on the
B-mode image just as in the case of A-mode. Some regions of the image can
be too dark -like shadowing- or too bright as in enhancement.
Errors can arise in the positioning or registration of features on the image
relative to the positions of the echo-producing structures in the tissues. Such
electronic misregistration causes the image of the structure to be displayed at
different locations, when the same structure is interrogated from different
directions by the ultrasound beam. This artifact can arise from the use of an
incorrect average speed of propagation in the instrument. It can also be
caused by misalignment, wear and other problems in the probe co-ordinate
measurement devices.
The artifact of incomplete imaging can occur in the B-mode display if the
scanning movement of the probe is too rapid in relation to the pulse repetition
frequency. The effect is an image consisting of the spokes of the wheel with
blanks between them. This can be corrected by slowing the movement of the
probe or else by increasing the pulse repetition frequency (prf).
Problems can also arise in the B-mode image due to patient movement
during image acquisition. In this case the structures being imaged may be at
different locations in relation to the face of the probe at different instants
during the image build-up. This difficulty can be overcome by ensuring that
the patient remains steady by holding his or her breath and by remaining
motionless.
memorise the set of images from a complete examination. These hard copy
photographs, either in the form of positive prints viewed in reflected light
or film transparencies viewed by transmitted light on a light box, may be
retained with the patient's case notes. This facilitates later review of the
case in the light of further developments, therapy, etc. The techniques
involved are discussed in chapter 9.
Another method of storing image information is video tape recording.
This also allows later recall and indeed photography as required. A dis-
cussion of this approach is also in chapter 9.
Electronic memory methods may also be employed for image storage,
but have not yet found wide application.
In all of these ways of permanently recording ultrasound images, it is
essential that as well as the image itself, a battery of background data also be
stored. Data such as patient name and number, reasons for the examination,
patient position and orientation, any patient preparation, machine settings
(frequency, type of probe, focussing, transmitter attenuator, limiter, sup-
pressor, TGC settings), plane of section, landmarks, angulation of section,
etc., all are essential information for the clinician. Some of the information
can, in some machines, be written on the image via a keyboard connected to
the scan converter memory. But if such facility is not available, it must be
manually written on the hard copy.
All of the instrument checks for the A-mode unit, described in section 4.13
are directly applicable to the B-mode instrument as well. Two further tests
for lateral resolution and of electronic registration are of particular relevance
to the B-mode instrument. Both of these tests may be carried out with the
AlUM (American Institute for Ultrasound in Medicine) test target, which is
ilIustrated in figure 6.16.
This target consists of an array of wire reflectors stretched between two
vertical walls. They are all immersed in an aqueous solution, such as de-
scribed in section 10.11, with speed of propagation 1540 m/s. The target may
be scanned through the open top of this bath. Also the square test object
can be positioned with any desired side presenting upwards to the probe.
To measure the lateral resolution the target may first be scanned from
direction A in figure 6.16. The right hand column of reflectors are imaged as
a column of parallel lines. The length of each line correlates with the beam
width at that depth. If there is a focus, the line length is least at the focus.
The lateral resolution at the focus may be quantified by turning the test
object around to allow scanning from direction B and arranging the water
depth so that the smalI bunch of wire reflectors at the middle are at the focal
STATIC B-MODE INSTRUMENTS 103
• •
J
• • ••• •
•
• •
•
2em. .1 em
,
.. SPACES • • SPACES
B •
• • •
•
• •
" .\
•
• • • • •
2em SPACES WIRE
REFLECTORS
Figure 6.16 The spatial arrangement of the wire reflectors in the AlUM (American
Institute for Ultrasound in Medicine) test object
length from the probe. When these wires are scanned the image is a series
of short lines arranged roughly end to end, but with each one in turn slightly
behind the previous one. When these neighbouring lines do not overlap,
lateral resolution holds. The separation for which the two neighbouring lines
just fail to overlap, is the lateral resolution at the focus.
This same test may also be done at other distances from the probe, where
the resolved separation would be larger than at the focus.
In the first stage of the previous test, to check the beam focussing, an
image of the column of parallel lines is obtained. Since these reflectors are all
equally spaced at 10 mm, the parallel lines should also be equally spaced at
10 mm separation on the x 1 scale display. If they are, this indicates that the
system average speed of propagation is indeed 1540 mis, the speed in the
liquid of the bath. If the image spacings are larger the system speed is too
great, and if smaller it is too small.
The latter test is a valuable adjunct to the test of electronic registration.
Two sets of data help to determine registration. One is the system average
speed of propagation and the other is the probe co-ordinate measurements.
The registration can be readily checked by sector scanning the test object
in two steps from the two upper corners. Each reflector wire should be
imaged as two crossed curved lines. In the case of correct registration each
such line should bisect its companion. If the lines otherwise intersect or fail
to touch each other, the machine registration is not in order. If in this latter
104 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
case the system speed is correct, the fault must lie with the probe position
and orientation sensors and servicing is called for.
A further check on the registration may be made by comparing the known
separations between wire reflectors in the test object and the distance be-
tween the corresponding points of intersection of the pairs of curved lines.
These should correspond regardless of the direction of the measurment.
In contact scanning the probe is moved across the skin overlying the tissues
of interest, acquiring the pulse-echo information about those tissues as it
moves. The image is built up during this scanning motion. An acoustic
coupling medium is needed between probe and skin to eliminate air from the
ultrasound beam path.
The main requirements of this coupling medium are that its acoustic
impedance be close to that of water and soft tissues; that it be biologically
acceptable on the skin (non-toxic, non-irritant, non-staining, easily re-
moved); that it flow and wet the skin and the probe, so as to take the various
shapes of these; that its fluidity be low so that it does not flow away from the
area of study too quickly, either under gravity or under the sweeping action
of the scanning probe.
Vegetable oils such as olive oil have been successfully used for this purpose.
They are possibly too fluid but can be readily removed between scans.
Aqueous gels have more favourable flow properties and are very widely used.
If during contact scanning excessive pressure is used, the tissues and
organs being examined can be deformed and erroneous images produced.
This is an especial problem with B-mode imaging of the breast and thyroid.
It also occurs with obese patients. In such situations it is common to use a
water path delay-line instead of contact scanning. This method is shown in
figure 6.17. A path of water solution with speed equal to 1540 m/s is inter-
posed between the transducer probe and the skin surface. This may be
achieved in various ways, but one typical method is to use a plastic bag, open
at the top with the bottom on the skin, as shown in the figure. Good contact
between the skin and the bottom of the plastic bag is achieved by using a gel
or oil. The probe may be freely moved about near the surface of the water
and the tissue imaging achieved in this way. The TGC curve would have a
delay at least as long as the water delay-line depth. Since reverberation occurs
due to the strong reflection at the bottom of the water bag the reverberation
artifacts are prevented from interfering with the tissue echoes signals of
interest by ensuring that the depth of the water, hw' is greater than the maxi-
mum depth of the tissue being investigated.
STATIC B-MODE INSTRUMENTS 105
Figure 6.17 A possible scheme for achieving non-contact delay-line scanning. A plastic
bag filled with a solution having a speed of propagation of 1540 m/s has an open surface
into which the probe is placed and about which the probe can freely move. The under-
side of the bag is acoustically coupled to the skin. The depth of the solution below the
probe provides the delay line
Static B-mode imaging, so-called because the target tissues must remain
motionless while the image is being acquired, is now widely applied to
regions throughout the body. It yields information about the shapes, sizes,
orientations and relative positions of different organs and tissues, in normal
and diseased states. It can be used to guide biopsy and aspiration needles to
the requisite target tissue.
Thus it is used at various stages during pregnancy to determine the position
and size of the foetus, to assess the internal anatomy and the maturity of the
foetus, to determine the location of the placenta, to evaluate a wide range of
problems and abnormalities of pregnancy , to safely guide the needle puncture
for amniocentesis and even foetal blood transfusion.
Static B-mode ultrasound is also the technique of choice in evaluating
gynaecological masses.
It is also widely used in examinations of the eyes, the thyroid gland,
abdominal aorta, liver, gall bladder, pancreas, spleen, kidneys, bladder,
scrotum and penis.
A very wide literature is available dealing with the multiplicity of applica-
tions and clinical conditions in which static B-mode imaging can with
advantage be used.
Even though static B-mode methods have proved a powerful tool for
investigating soft tissue structures throughout the body they do have limita-
106 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
6.15 BIBLIOGRAPHY
Annual Reviews
The basic idea in this technique is simply to rotate the sector scanning probe
very rapidly, i.e. much faster than any of the internal body structures being
imaged. In this way, the image can be acquired so quickly that there is not
appreciable movement of the structures during an image acquisition.
This can even be done manually. All that is required is that the pulse
repetition frequency be as high as possible, that the scan converter be
double-ended and that the operator be able to maintain the rapid sectoring
motion for a period of time. The image acquired is then a moving image if the
structures are moving, and therefore can only be viewed on an oscilloscope
screen with very short persistence or on a television monitor. For permanent
storage, a moving film or a video tape is needed.
Usually the rapid sector scanning is carried out automatically, with the
probe motion being motor-driven. Two typical systems for achieving this
are shown in figure 7.1. In figure 7.I(a), is shown a system where the probe
is rocked back and forth, by an appropriate drive mechanism. The probe is
totally immersed in an oil bath and the ultrasound passes from the probe
DRIVE
MECHANISM
(a) 'WINDON
. OIL"
4 P
(b) '»'WINDOW
Figure 7.1 Two alternative ways of implementing a rapid angular motion of the probe
for real-time scanning. (a) A single probe which is made to execute reciprocating
motion. (b) Four probes in cruciform arrangement which rotate, but of which only one
transducer is active at any instant
110 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
through a layer of oil out into the patient through a thin plastic window.
Thus, the probe holder as a whole may be placed on the patient's skin and the
sectoring achieved by the probe motion inside the overall probe holder. A
coupling gel is required between the window and the skin. Another technique
which is more simply implemented is that shown in figure 7.1(b). Here there
are four identical probes attached to a common axle which rotates in one
direction with only the probe which is positioned in the quadrant facing the
window, electrically active and connected to the B-mode instrument at any
moment. Thus, each single probe follows its predecessor into the active
region, and only one probe is active at each instant. The continuous rotation
is more simply implemented than the reciprocating motion required with the
set-up of figure 7.1(a).
In each of these cases, the probe co-ordinate measuring device and the
rest of the electronics and display system can be exactly as in the static grey
scale B-mode instrument of figure 6.10. Typically, a grey-scale system in-
corporating a double ended analogue scan converter or a digital scan con-
verter with a television monitor is used. These instruments are also usually
equipped with a stop-action switch or freeze-frame so that a particular static
scan can be obtained and a permanent record obtained as in the case of the
conventional static B-mode images.
Among the drawbacks of this system, is the fact that the transducer probe
holder can be fairly heavy and fatiguing to operate.
The mechanical drive is more liable to faults than an electronic system.
The system as a whole is not portable.
00000000 DO
12345678 ................. n
Figure 7.2 A linear array of n rectangular elements in a probe
DYNAMIC (REAL-TIME) B-MODE SCANNING III
SKIN ORGAN
~
MULTI-
ELEMENT STRUCTURE
ARRAY IMAGED
2-D
IMAGE
Figure 7.3 The formation of a B-mode image with a multi-element array. Each
element obtains the pulse-echo data about a line through the tissues and these data are
displayed in a spatial arrangement corresponding to the spatial arrangement of the
transducer elements
of the scan is defined by the set of beams travelling out from the identical
transducers in the array. The resulting image is constructed on the screen by
assigning a particular horizontal line location for the relevant set of bright
spots from each transducer element in the array. The relative positioning of
these horizontal lines in the display corresponds to the relative positions of
the beams emanating from the transducer elements. The actual separation of
these horizontal lines on the screen is set by the actual separation of the
transducer elements as well as by the scale factor assigned in the oscilloscope
controls. The bright spots and their positions across the horizontal direction
are set by the pulse-echo determined depths of the echoing structures
involved.
This complete sequence of activation of all the elements of the transducer
array is carried out repeatedly at a repetition rate something greater than
25 Hz in order to produce aflicker-free image to the viewer. Clearly, if the
organs being investigated are moving, the effect is a moving B-mode image
on the screen.
Certain factors tend to militate against the quality of the image produced
by this technique. For instance, the separations between the transducers and
therefore between the beams of ultrasound, produce gaps between the
horizontal display lines on the oscilloscope and cause blank striations in the
112 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
B-mode image. Also, the individual small transducers have a relatively short
near-field and so have poor resolution at much shallower depths than the
single larger transducers of the static scanner or the mechanical sector
scanner. Another cause of image degradation is the fact that the beams
cannot impinge on all the interfaces of a complex organ at 90°. This is the
limitation of the linear scan, discussed in section 6.3.
In an effort to overcome these difficulties, it is more common to activate
the transducer elements in groups of for instance, 3 or 5 at a time thereby
producing composite ultrasound beams. Thus the complete cycle of opera-
tions would start with transducers 1 to 5 active, then transducers 2 to 6, then
transducers 3 to 7 and so on. The echoes are displayed on the screen along the
axis of the middle transducer of the active group. This helps to improve the
resolution and the detail of the image.
MULTI-
ELEMENT
ARRAY PULSE
GENERATOR
SWITCH
ELEMENT
ADDRESS SCAN
LOGIC I---~--I CONVERTER
C)
TV
DISPLAY
Figure 7.4 Block diagram of a multi-element array dynamic B-mode scanning instru-
ment, showing the interconnections between the functional blocks
elements. The degree of focussing can be controlled and the focal distance
can be set close to or far away from the transducer.
Furthermore electronic means exist to cause the active groups of trans-
ducers to function in a focussing manner when receiving echoes as well.
Thus there are interposed between each transducer and the summing re-
ceiver amplifier a delay line, as shown in figure 7.5, with the actual delay in
each line controlled electronically. If line 3 has a long delay, lines 2 and 4
shorter delays and lines 1 and 5 no delays, the receiver acts like the focussed
transmitter, in reverse. A plane wavefront approaching the array as shown in
the figure, strikes all the elements simultaneously. But the signals from
elements 1 and 5 reach the summing amplifier and the display, in advance of
the signals from elements 2 and 4. These latter are also displayed in advance
of the signal from element 3. The group acts as an electronically focussed
receiver. Control over the delays allows control over the degree offocussing
and the length of focus. Normally the receiver focussing would be chosen to
match the transmitter focussing.
WAVEFRONT DELAY
MOVEMENT LINES
2
RECEIVER
3
c:=>--HAMPLIFIER
4
PROBE
ELEMENTS
Figure 7.5 A group of elements can act as a focussed receiver if delay lines are inter-
posed between the elements and the mixing receiver amplifier as shown. In this set-up,
the wave front shown produces signals in elements 1 and 5 which reach the mixer first
and in advance of the signals from elements 2 and 4. The last signal to reach the mixer
is that received by element 3. Electronic focussing is achieved in this manner. The
range of delays in the delay lines may be varied and so the degree of focussing in the
receiver array may be controlled
1fZl
21Z1
31Z1
4EZl
5EZl DIRECTION
Figure 7.6 Steering of the composite beam produced by five elements, may be achieved
by introducing a delay between the stimulation of each element in the sequence from
I to 5. Thus element 1 is first stimulated, then after a set delay, element 2 and so on
through all the elements. Control of the delay used sets the orientation of the com-
posite beam
pulsed a little later than element 2, 4 is later than 3 and element 5 is pulsed
last of all. In this way, the effective composite beam is directed downwards
at some angle relative to the original composite beam, and the angle is
determined by the relative delay introduced between the pulsing of 1 and
2,2 and 3, 3 and 4, and 4 and 5. By constantly varying the delay between the
excitation of the active elements, the effective beam can be made to electronic-
ally sector-scan through the body tissues as shown in figure 7.7. In this way
sector-scanning can be achieved electronically and the arrays driven in this
way are sometimes referred to as phased arrays.
PHASED AR RAY
,
/
, / ",
,/ ",
/
BEAM SECTORING
Figure 7.7 Electronic sectoring, by steadily varying the delay used in the steering of the
composite beam, can effect the interrogation of an extensive cross-section of tissues by
a narrow beam. Such an array is called a phased array
WAVEFRONT DELAY
MOVEMENT LINES
RECEIVER
}--+--1
AMPLIFIER
PROBE~
ELEMENTS
Figure 7.8 A group of elements acting as a composite receiver may be endowed with
directionality by introducing delay lines between the elements and the mixing receiver
amplifier. If the delays introduced increase linearly across the array as indicated, the
incident wave on element 5 is detected by that element but the signal is delayed more
than the signal incident on element 4 and so on across the array. In consequence a
wave front approaching as shown produces signals, all of which are added or mixed
into the receiver amplifier simultaneously. The array is oriented in the direction along
which this wave front is travelling. Varying the delays in the delay lines across the
array varies the directionality
first encounters element 5 and its signal is delayed a large amount until the
wave front strikes element 1. Likewise the signal path from each other
element has a proportionately shorter delay so that all the elemental signals
combine simultaneously at the amplifier input. By varying the increase of
the delay from one element to the next, the directivity of the composite
receiver can be controlled.
Such electronic sector-scanning helps to overcome the limitation of linear
scanning whereby only structures more or less at right angles to the beam
can be detected and displayed. Since the effective angle of the beam can be
varied, many more structures and interfaces can be detected and a more
complete image can be formed (see figure 6.5).
body, some of the structures of interest will not be seen and the image will
only be partial. As shown in figure 7.7, the phased array technique can help
to overcome this limitation too, since with a relatively small array one can
interrogate much more of the tissues. The ability to have dynamic focussing
does help to improve the resolution of the technique in the focal region, but
the divergence of the beam in the far field remains a problem for imaging the
deeper structures in the body. A drawback of the linear array technique is the
striated nature of the image, due to the necessary spacing between the
elements. Smoothing in the scan converter can help this.
The width of the beam perpendicular to the plane of the linear array gives
rise to other problems. In the linear arrays the beam, effectively a composite
beam, is not circular but mainly rectangular in shape and the width of the
beam perpendicular to the plane of scan is a cause of poor resolution in this
direction. While dynamic focussing improves the lateral resolution in the
direction along the array, the resolution in the direction perpendicular to the
linear array is not improved. Frequently, a small amount of acoustic lens or
internal focussing is used in this direction, but this is a fixed quantity and
usually cannot be a large improvement. Thus it should be borne in mind in
relation to the multi-transducer array systems, that lateral resolution has two
aspects and while dynamic focussing can improve one, it does not affect the
other.
The dynamic B-mode instruments may be used in all the clinical situations
in which static B-mode imaging has been used. Indeed since in most tissues
and organs there is considerable small-scale movement due to blood flow,
muscle action, respiration or heart contractions, the dynamic views offered
by the real-time units open a new perspective on ultrasound imaging.
Generally, the multi-transducer array B-mode instruments can be im-
plemented in a more compact and even more portable unit, compared with
static B-mode instruments. This is mainly because they do not require the
complex mechanical systems for determining the probe co-ordinates. These
instruments are coming to be very widely used in obstetrics for investigating
the position and dimensions of the foetus, even when the foetus is moving
about. These investigations can be done at the patient's bed-side in the ward
rather than in a specific examination room. All of the required foetal measure-
ments can therefore be made much more simply and cheaply than with the
static B-mode instrument.
Another major area of application of the real-time instruments is in the
investigation of the heart and the major vessels. The heart wall movements,
the dynamics of the heart valves, the changes in the heart chamber dimen-
sions, etc., all may be studied with the real-time machines. Even foetal heart
activity may be investigated.
The real-time instruments can also be used for the examination of ab-
dominal organs affected by respiration, such as the liver, spleen, kidneys and
gall bladder. In these cases the images achieved up to the present tend not to
be as good as those obtained with the static B-mode instruments. So for
general survey/orientation investigations, the dynamic scanners are best. For
fine-detailed images the static instruments retain the edge.
DYNAMIC (REAL-TIME) B-MODE SCANNING 119
7.10 BIBLIOGRAPHY
Chang, S., Echocardiography: Techniques and Interpretation, 2nd edn, Lea & Febiger,
Philadelphia, 1981
Feigenbaum, H., Echocardiography, 3rd edn, Lea & Febiger, Philadelphia, 1981
Fleischer, A. C. and James, A. E., Introduction to Diagnostic Sonography, John Wiley,
New York, 1980
Harrison, D. C. et al. (Eds), Cardiovascular Imaging and Image Processing: Theory and
Practice-· 1975, Society of Photo-Optical Instrumentation Engineers, Palos Verdes
Estates, Ca, 1975
James, A. E. Jr. (Ed.), Radiological Clinics of North America, Vol. 18-1: Symposium on
Advances in Ultrasonography, W. B. Saunders Co., Philadelphia, 1980
Kisslo, J. A. (Ed.), Two-dimensional Echocardiography, Churchill Livingstone, New
York,1980
Linhart, J. W. and Joyner, C. R., Diagnostic Echocardiography, C. V. Mosby Co., St
Louis, Mo, 1981
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
Short. M. D. et al. (Eds), Physical Techniques in Cardiological Imaging, Adam Hilger
Ltd, Bristol, 1983
Taylor, K. J. W. et aI., Manual of Ultrasonography, Churchill Livingstone, New York,
1980
de Vlieger, M. et al. (Eds), Handbook of Clinical Ultrasound, John Wiley, New York,
1978
Wade, G. (Ed.), Acoustic Imaging: Cameras, Microscopes, Phased Arrays and Holo-
graphic Systems, Plenum Press, New York, 1976
Weyman, A. E., Cross-Sectional Echocardiography, Lea & Febiger, Philadelphia, 1982
Winsberg, F. and Cooperberg, P. L. (Eds), Real Time Ultrasonography, Churchill
Livingstone, Edinburgh, 1982
Annual Reviews
Kurjak, A. (Ed.), Progress in Medical Ultrasound: Reviews and Comments, Excerpta
Medica, Amsterdam, annually from 1980
8 Doppler Instrumentation
Clinical ultrasound instruments based on the Doppler effect are widely used
to detect and measure the movement of internal structures in the body. A
variety of such instruments exist, and they can be broadly categorised into
continuous wave (cw) and pulsed wave (pw) instruments.
After studying this chapter the student should be able to:
(a) define the Doppler effect;
(b) describe the Doppler effect as encountered in echo-based diagnostic
ultrasound;
(c) schematically outline a continuous-wave Doppler instrument and
discuss the functioning of each component block together with their
interrelations;
(d) show how the absolute velocity of body structures may be obtained
from such a Doppler unit;
(e) describe in general terms how such an instrument may be adapted to
measure both magnitude and direction of the reflector velocity;
(f) discuss ways in which such cw Doppler instruments may be cali-
brated and checked;
(g) critically review the clinical applications of cw Doppler units and
their limitations;
(h) outline in block fashion a pulsed Doppler instrument for measuring
blood flow;
(i) describe the functions of the blocks in this instrument together with
their interconnections;
CD show how such a pulsed Doppler instrument may be modified to
yield images, typically of vessels in which blood flow is occurring;
(k) describe tests to check the performance of such pulsed Doppler
instruments;
(I) critically review the clinical applications of these units.
DOPPLER INSTRUMENTATION 121
8.2 DOPPLER EFFECT
J
(a) ~
cose,
1
1
--41---
8· --'
f;
~
(b)
Figure 8.1 The Doppler effect occurs when a wave of frequency f; is incident (a)
normal to a reflector moving with a velocity v m/s and (b) obliquely with angle of
incidence OJ to the moving reflector. In the inset is shown the dependence of cos OJ on
the value of (}j
the direction of the beam. If the frequency of the incident wave be 1;, the
reflected wave will have a different frequency,fr' This shift in frequency the
Doppler shift, arises as follows. The incident wave approaches the interface
at a speed c(m/s), which is the speed of propagation of ultrasound in the first
medium. The interface is moving to meet that incident wave at a speed of
v(m/s). Therefore, each succeeding maximum of the incident pressure wave
encounters the reflecting interface thereby producing the pressure maximum
of the reflected wave, sooner than would have been the case if the reflecting
interface were stationary. In fact, the wavelength of the reflected wave (}'r)
122 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
is shorter than that of the incident wave (A), or in other words the reflected
frequency is greater than the incident frequency. The shift in frequency jj~
is given by equation (S.1):
iJf=f,-f.
= +t;v (S.l)
- c
If the motion of the reflecting surface is in the opposite direction, with the
surface receding from the source, then the magnitude of the Doppler shift is
negative.
A second Doppler shift of equal magnitude occurs when a static transducer
receives the echo from the moving reflector 'source'. Thus the overall or total
Doppler shift iJfT' in this case is given by equation (S.2):
iJf
2rv
= +_.l_i.
. T - C
(S.2)
If the angle of incidence (}i' of the wave on the reflecting interface is greater
than zero as shown in figure S.1(b), then only a component of the reflector
motion, \. cos (}i' is along the direction of the incident wave and the total
Doppler shift is determined by that component as shown in equation (S.3):
At'T-±---
_ ~t; vcosO i
Ll. (S.3)
c
r--~--t LOUDSPEAKER
FREOUENCY
ANALYSER
CD CD
DDuu
Figure 8.3 Alternative designs of continuous wave (cw) Doppler probes used in
medical applications
returning echoes to the receiver transducer in the probe. This means that the
receiver transducer is constantly receiving echoes of frequencies equal to the
originally-transmitted frequency (from stationary structures) as well as
Doppler-shifted frequency echoes (from moving structures). There is a
tuned amplifier in the unit directly behind the receiver transducer to preferen-
tially boost all of the echo signals. Note that there is no provision for time
gain compensation (TOC) since there is no way of distinguishing the depth
from which echoes are received in this system.
After the amplifier, the echo signals proceed to the discriminator or FM
demodulator. The discriminator is of a different type from the demodulator
in the pulse-echo instrument. The discriminator is aimed at extracting the
magnitude of the Doppler shift from those echo signals which return from
moving structures. It is therefore a frequency demodulator which compares
the frequency of the received echo signals with the frequency originally
generated by the transmitter oscillator. It generates a voltage signal of a
frequency equal to the absolute value of the Doppler shift. This means that
it does not distinguish between whether the Doppler shift is positive or
negative or whether the moving structure is moving towards the probe or
away from it.
As shown by the calculation earlier, the frequencies produced in many
practical clinical applications of these instruments are in the audible sound
range. Consequently, this so-called Doppler signal can be sent through an
DOPPLER INSTRUMENTATION 125
amplifier to earphones or to a loudspeaker, and can be listened to. The per-
ceived pitch of the sound is determined by the Doppler shift which, in turn,
is determined by the speed of the moving structure in the body.
This Doppler signal can be recorded on tape or further analysed. This
further analysis will be considered later.
Consider the situation where there are reflectors in the beam which have
a range of speeds, both towards and away from the transmitter transducer.
Assume also some stationary reflectors. The received echo signal now con-
tains a range offrequencies above and below the transmitted frequency, i.e.
it contains a spectrum extending on either side of the transmitted frequency,
1;, as shown in figure 8.4(a). Compare this spectrum with the transmitted
spectrum shown in figure 8.4(b). Discrimination subtracts any of the trans-
mitted frequencies from the received frequency spectrum as shown in figure
8.4(c), and also translates or shifts those frequencies down close to zero.
Those received frequencies which are greater than the transmitted frequency
are transferred to their relevant Doppler-shift frequencies close to zero.
Those received echo signals which have frequencies lower than the trans-
mitted frequency are also transferred close to zero, the frequencies equal to
the absolute value of their Doppler shifts. Therefore, the discriminated
signal is a mixture of the two original sidebands of the received signal, but
now in the low frequency or audio range as shown in figure 8.4(d). Therefore,
the audio signal does not distinguish between positive and negative Doppler
shifts, and so it does not distinguish between echo signals coming from
those reflectors moving towards and those moving away from the transmitter.
This system rejects the directional information in the signal.
~II
(a) ~
!f j
~I
(b) A !fj f
I~I ,
(c) ni/\ fj
~II(\
(d)
Figure 8.4 The signal processing implemented on the spectrum of the received echo
signals, shown in (a), by a non-directional Doppler unit. The transmitted spectrum is
shown in (b), so that the Doppler shifted portions of the received spectrum are as shown
in (c). In the discriminator the received spectrum is mixed with the transmitted spectrum,
and the result is a spectrum of the frequency differences between received and trans-
mitted spectra. This new spectrum is down in the audible range of frequencies. In the
non-directional instrument this new spectrum is derived in a process which considers
only the magnitude of the frequency difference between received and transmitted fre-
quencies. The output spectrum in (d) therefore is a blend of components due to the
positive Doppler shifts and the negative Doppler shifts in (c)
The overall action of the system is illustrated in figure 8.5. When used to
measure blood flow the discriminator generates the Doppler signal, the fre-
quency of which is related to the absolute value of the red blood cell velocity.
The zero-cross detector then generates a voltage, whose amplitude is directly
proportional to the root mean square (rms) of the Doppler shift frequencies.
Overall, therefore, the output voltage amplitude of the zero-cross detector
is directly proportional to the magnitude of the rms blood velocity.
In streamline or non-turbulent flow, the rms velocity is proportional to the
average velocity. Then the zero-cross output voltage amplitUde is propor-
tional to the average velocity of the blood and may be calibrated in average
velocity.
DOPPLER INSTRUMENTATION 127
(a)
lei
(b)
lei
(c)
Ivl rms
Figure 8.5 (a) The relationship between the magnitude of the Doppler shift frequency
output from the discriminator and the magnitude of the reflector velocity. (b) The
relationship between the amplitude of the output voltage from the frequency meter
circuit and the root mean square Doppler shift signal frequency. (c) The overall per-
formance of the instrument with frequency meter, is summarised in the relationship
between the amplitude of the output voltage signal and the root mean square reflector
velocity
of the moving structures and tissues, i.e. it yields the amplitude of each fre-
quency component present. Iffor instance, these amplitudes are varying with
time, this analysis must be performed continuously.
In some cases, such frequency spectrum analysis is carried out off-line.
The Doppler-shift signals are first tape recorded and the analysis is carried
out subsequently. Many analogue spectrum analysers are available on the
market and their operation is equivalent to an array of band-pass filters,
each terminated with a measurement meter. The pass-bands of the filters
cover neighbouring ranges of the frequency scale.
In recent years digital computer techniques using programmes involving
fast Fourier transforms (FFT) are increasingly being used for this purpose.
To implement such analysis the Doppler-shift signal must first be sampled
and digitised (see Appendix L). After the computer analysis the spectrum
can be reconverted to an analogue form for recording and display. The most
common form of display is a graph of Doppler-shift frequency against time
with the spectral amplitudes coded into a grey scale. Thus a high amplitude
spectral component would be darker than a low amplitude component.
TX
RX
PHASE
FREQUENCY TO
COMPARATOR
VOLTAGE
CONVERTER
DI FFERENTIAL
AMPLIFIER
Figure 8.6 Block diagram of a directional Doppler system, showing the main func-
tional components and the inter-relationships between them
ultrasound beam and measure the output amplitude of the frequency meter.
Gradually increase the steady flow in the tube and obtain a set of data pairs
to draw the graph of figure 8.5(c).
Another method of checking the performance of a cw Doppler instrument
is by using the test vessel with vibrating base described in chapter 5 for
testing M-mode instruments. The vibratory reflecting base has a sinusoidal
velocity, the maximum value of which (2nfA) can be varied either by
changing the frequency (f) of the electromechanical oscillator or the ampli-
tude (A) of that motion. Also note that this motion provides equal reverse
and forward phases of the reflector motion.
The ultrasound beam is set perpendicular to the bottom of the vessel. The
amplitude of the frequency meter output voltage is recorded and should be
a sinusoidal graph of amplitude proportional to 2nfA. The calibration
graph of figure 8.5(c) can be derived from individual points on this sinusoid.
Indeed if the instrument is a directional Doppler unit a calibration graph
such as that of figure 8.7 may be derived, since known forward and reverse
velocities are presented to the ultrasound beam.
lei
Figure 8.7 The calibration graph for a directional cw Doppler instrument is essentially
two graphs which are plots of voltage amplitude versus amplitude of forward reflector
velocity (as registered on one meter) and of voltage amplitude versus reverse reflector
velocity (as registered on a second meter)
(a) MEAN
t
(b)
Figure 8.8 Two Doppler frequency versus time graphs showing the parameters used
to calculate the Pulsatility Index, (a) for a high index and (b) for a low index
132 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
If two Doppler flow detectors are simultaneously applied up-stream and
down-stream on the same artery, a record such as that in figure 8.9 can be
obtained. From this record, the transit time, the time delay between the
arrival of the velocity pulse at the start of the length of artery and its down-
stream end can be obtained. Since the distance between the two measuring
points can be measured, the pulse wave velocity, a measure of the stiffness
of the arterial wall, can be calculated. Furthermore, the ratio of the pulsa-
tility indices at the down-stream and up-stream locations is another useful
parameter called the damping factor. This parameter, if it is high, indicates
stenosis, while a low value correlates with normal flow, and an intermediate
value is often related to an aneurysm.
The Doppler flow detectors can also be used for studying the flow in the
veins and often they are used to indicate the patency of the veins in the limbs.
Thus, the major types of information derived from the Doppler flow
meter concerns heart-rate and the state of the health of the blood vessels.
While they detect the flow of the red blood cells, it is not possible to use
these instruments to accurately measure the volume flow rate because it is
rarely possible to determine accurately the angle of incidence (}p between the
incident ultrasound beam and the moving red blood cells. Also it receives
and analyses simultaneously the Doppler shift signals from red blood cells
moving at a variety of velocities across the diameter of the vessel and is not
capable of yielding the velocity profile across the vessel diameter. Basically,
the instrument yields a qualitative indication of the flow.
UPSTREAM
t
f
DOWNSTREAM
t
Figure 8.9 Two simultaneously measured Doppler frequency versus time graphs
from two points on the same arterial segment, indicate the meaning of the Transit Time
FREOUENCY
DIVIDER
(p. r. f.)
fm COMPARISON
r-----Oi---!
OSCILLATOR
DOPPLER
SIGNAL
OUTPUT
this instrument. the driving voltage oscillations from the master oscillator
are gated to produce the effect of a pulsed oscillation drive to the transmitter
probe. A pulse of ultrasound offrequencY.li' is transmitted into the body. In
order to ensure that each pulse being fed to the transmitter is identical to the
others. the gate opening times are keyed to the driving frequency signal but
an exact sub-multiple (for example 10 3) of that frequency. The pulse
repetition frequency would then be 10 3 of .Ii' The received echoes are
amplified before discrimination of FM demodulation. The discrimination
used is similar to that described for the directional Doppler system earlier.
The comparison frequency generated by the comparison oscillator, .1m , is
slightly less than/i' so that when the FM demodulation is done. the positive
and negative Doppler shifts are preserved intact and separate.
Notice that since the voltage drive to the transducer is pulsed in this
instrument. the transducer must have some damping, very similar to the
pulse-echo transducers. Two separate transducers. one for transmitting and
one for receiving can be used, or else a single transceiver.
Finally, the FM demodulated signal is passed through a range gate, which
is opened at some delay after the original transmitted pulse. The delay used
may be varied. so that the pulse-echo signals from different depths can be
examined in isolation as shown in figure 8.11. Also. the duration of the
opening of the sample gate. which is the same as the duration of the output
134 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
T X / R X_
fR_O
_B _ ---~ E GATE SLICE
ES=JA-«>IMIPL"'
__
I<>
PROBE HOLDER
Figure 8.12 A scheme which may be used to determine the absolute velocities of the
blood in an artery, whose angle to the skin is not known
directions. The assembly is placed on the skin as shown and a coupling gel
is used to ensure that the ultrasound propagates efficiently into the tissues.
The artery inside is at some angle which is unknown relative to the skin.
The zero-crossing detector output from the machine is monitored, using
each of the two probes in turn. The position of the probe holder on the skin
and its angle relative to the skin are varied until the zero-cross outputs from
both probes are identical but of opposite polarity. At this position of the
assembly, one probe makes an angle rJ. with the positive direction of flow in
the artery while the other makes the same angle rJ. with the negative direction
of flow in the artery. This angle may then be used in the original Doppler-
shift equation instead of the angle 8j • Then the actual velocity of the blood in
the artery and indeed the velocity of the blood at different positions across
the lumen of the artery may be calculated, using the Dopper-shift equation
applied to the output of the pulsed system.
The range-gated instrument can also measure the diameter of the artery
by measuring the difference in range between the closest and furthest points
of no flow, as well as measuring the velocity of the blood flow at different
radial positions across the artery. Therefore, it can be used to provide data
to calculate the volume flow rate of blood in the arteries. It offers the promise
of quantitative information about blood flow in arteries and veins.
If the arrangements shown in figure 8.13 are added to the original system
of figure 8.10, the pulsed-Doppler instrument can be used to image the
location of the moving reflectors, for instance the flowing blood within the
artery. A saw-tooth voltage is used to electronically sweep the delay and also
to provide Y deflection, i.e. depth deflection on the oscilloscope display. The
zero-cross ()utput voltage is used to drive the Z or brightness input of the
oscilloscope. Finally, a linear potentiometer can be used to detect the
position of the probe along a linear track and the voltage from this potentio-
meter is used to move the display on the oscilloscope along the horizontal
or X axis. Thus, as the probe is moved slowly along the X track while also
being drawn over the skin, the delay is repeatedly swept and the Doppler
shifts determined at the various depths. Whenever there is a moving re-
flector producing a Doppler shift, a bright spot is displayed on the os-
cilloscope.
In this way, the full extent of an artery can be imaged on the screen as
indicated in the diagram. Only the positions of moving reflectors producing
Doppler-shift signals are displayed on the image. The level of the voltage
required to produce the bright-up can be arranged with a suppressor
threshold so that small voltages such as would be produced from flow in
veins can be suppressed.
Use of a scan converter allows a grey-scale display to be implemented.
FREQUENCY TO
- __- - - - / VOLTAGE
DOPPLER CONVERTER
SIGNAL
DEP'Hj~ Z
PROBE
POSITION
DETECTOR
Figure 8.13 The additional functional blocks to those shown in figure 8.10, that are
needed to image blood vessels with pulsed Doppler techniques
DOPPLER INSTRUMENTATION 137
8.10 PERFORMANCE CHECKS FOR PULSED DOPPLER
INSTRUMENTS
Adaptations of the test rigs for cw Doppler units may be used for checking
the performance of pulsed Doppler instruments.
The tube carrying the calibrated luminar flow of milk or blood can be
immersed in a bath of solution with speed of propagation 1540 m/s. This
flow can be measured with the pulsed Doppler unit, by directing the probe
towards the tube from the surface of the bath. The velocity profiles and the
tube diameter may be determined for a range of liquid flow rates. Since the
diameter and the actual velocity profile are known a priori, the instrument
performance can be checked. The same test rig can be used to assess the
imaging performance of the pulsed Doppler imager, at different flow rates.
The bath with vertically vibrating base can also be used to check the
operation of the pulsed Doppler unit. Since the velocity of the base is
known and the depth of solution in the bath can be varied through known
values, both the Doppler-shift function and the range (delay) calibration
may be checked. The Doppler shift for both forward and reverse reflector
velocity can be calibrated in the same manner as for the cw instrument. The
image calibration can be assessed by simply varying the height of the trans-
ducer face above the moving base of the bath. The range according to the
instrument should correspond to the measured depth in the liquid (of
propagation speed 1540 m/s) in each case.
The main uses of the pulsed Doppler instruments are in the study of arterial
blood flow and in imaging arteries. Commercial instruments specially
designed for imaging the carotid artery bifurcation are available. Some of
these instruments incorporate grey scaling in the display where the voltage
to the Z input, which is proportional to the Doppler-shift frequency, de-
termines the brightness of the spots on the display. Some instruments
employ a colour coded display to represent the range of frequencies present.
Many new clinical applications are being developed and reported in the
literature and it is likely that these applications will increase as years go by.
There are also on the market a number of pulsed Doppler instruments for
quantitative analysis of blood flow. As mentioned previously these offer the
possibility of quantitatively measuring the blood flow rate in vessels in the
safest and most non-invasive method yet devised. It is certain that these
applications will multiply in the coming years.
138 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
New applications are also being developed in which these instruments are
used to quantitatively examine other moving structures in the body such as
the heart valves and walls, the motion of the diaphragm, the various motions
associated with the larynx and other throat structures, the motions of
sphincters and other structures in the abdomen.
The potential and indeed the detailed structures of these instruments are
developing and evolving. Many new developments in this area can be
expected in the years ahead.
8.12 BIBLIOGRAPHY
Atkinson, P. and Woodcock, J. P., Doppler Ultrasound and its Uses in Clinical Measure-
ment, Academic Press, London, 1982
Biidingen, H. J., Doppler-Sonographie der Extrakraniellen Hirnarterien, Georg Thieme
Verlag, Stuttgart, 1982
Harrison, D. C. et at. (Eds), Cardiovascular Imaging and Image Processing: Theory and
Practice-1975, Society of Photo-Optical Instrumentation Engineers, Palos Verdes
Estates, Ca, 1975
Hatle, L. and Angelsen, B., Doppler Ultrasound in Cardiology: Physical Principles and
Clinical Applications, Lea & Febiger, Philadelphia, 1982
Hwang, N. H. C. and Normann, N. A. (Eds), Cardiovascular Flow Dynamics and
Measurements, University Park Press, Baltimore, 1977
James, A. E. Jr. (Ed.), Radiological Clinics of North America, Vol, 18-1: Symposium on
Advances in Ultrasonography, W. B. Saunders Co., Philadelphia, 1980
Kriessmann, A., Praxis der Doppler-Sonographie, Georg Thieme Verlag, Stuttgart,
1982
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
Reneman, R. S. (Ed.), Cardiovascular Applications of Ultrasound, North-Holland,
Amsterdam, 1974
Roelandt, J., Practical Echocardiology, Research Studies Press, Forest Grove, Or, 1977
Rolfe, P. (Ed.), Non-invasive Physiological Measurements, Vol. I, Academic Press,
New York, 1979
Rose, J. L. and Goldberg, B. B., Basic Physics in Diagnostic Ultrasound, John Wiley,
New York, 1979
Short, M. D. et at. (Eds), Physical Techniques in Cardiological Imaging, Adam Hilger
Ltd, Bristol, 1983
de Vlieger, M., White, D. N. and McCready, V. R., Ultrasonics in Medicine, Excerpta
Medica, Amsterdam, 1974
de Vlieger, M. et at. (Eds), Handbook of Clinical Ultrasound, John Wiley, New York,
1978
Webster, J. G. (Ed.), Medical Instrumentation: Application and Design, Houghton
Mifflin Co., Boston, 1978
Wells, P. N. T., Biomedical Ultrasonics, Academic Press, London, 1977
Woodcock, J. P., Ultrasonics, Adam Hilger Ltd, Bristol, 1979
Annual Reviews
Kurjak, A. (Ed.), Progress in Medical Ultrasound: Reviews and Comments, Excerpta
Medica, Amsterdam, annually from 1980
White, D. N. (Ed.), Ultrasound in Medicine, Plenum Press, New York, annually from
1975
9 Permanent Records of Ultrasound
Examinations
The retina of the eye is equipped with specialised light receptors, the rods
and cones, which when light impinges on them produce nerve impulses
which travel up the optic nerve through various intermediate structures to
the visual cortex of the brain where the actual perception occurs. Each
retina contains some 100 million rods and 5 million cones. The latter are
densely packed in the central portion of the retina, the fovea centralis. while
the rods are distributed mainly over the periphery of the retina. The rods are
sensitive to very low light intensities but are poor at distinguishing fine
details in the pattern presented to the retina. The cones are good at dis-
tinguishing fine detail in the pattern incident on them provided the in-
tensity of the light is great enough. The cones are also sensitive to colour.
brightness and differences in levels of brightness (contrast).
Light is an electromagnetic radiation and the visible part of the electro-
magnetic spectrum extends from wavelengths of about 420.um to 700 pm.
At the higher end, the spectrum stretches into the infrared with wavelengths
greater than 700.um, while at the lower end, at wavelengths less than
400.um the spectrum extends into the ultraviolet. Beyond the ultraviolet
the spectrum passes into X-rays and at still shorter wavelengths, gamma rays.
As the wavelength increases beyond the infrared. the radiation is known as
radio waves.
The wavelength of the light determines the colour or hue perceived by the
eye. In most situations a range or mixture of colours are simultaneously
present and a quantity called the saturation is a measure of the purity of the
colour perceived. A very narrow band of wavelengths would have a high
saturation, while a wide band of wavelengths would yield a low saturation.
For most methods of presenting ultrasound images, a low saturation holds
and the colour perceived is a grey. The luminance or brightness of the grey
can range between the two limits of black and white. This scale is sometimes
referred to as monochromatic or achromatic or grey scale. The brightness is
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 141
closely related to the physical intensity of the light or its luminous emittance
the light power per square metre. Since the eye is not equally sensitive to
all colours or hues. the wavelength also has an influence on the brightness
or perceived intensity.
The contrast between different light intensity levels is of great importance in
visual perception since visual sensitivity is best when differences in intensity or
brightness are presented to the retina. Contrast C, is defined as
(9.1)
where 1d and 1'.2 are the two visible luminous intensity levels being com-
pared.
The ability of the eye to distinguish between brightness levels close to
each other is improved if the ambient brightness is minimised and if the eye
is allowed enough time to undergo dark adaptation or acclimatisation to a
dark environment. Even under these optimum conditions the eye is not
equally sensitive to the same contrast at all the brightness levels between
black and white. At very low brightness levels a very large contrast is needed
for its perception. At this stage the rods are the predominant receptors. At
high levels of brightness. contrast levels of around l/r, or 2~{) can be de-
tected. The cones are the receptors producing this type of performance. For
this reason the perceived brightness of a grey level depends on the neighbour-
ing or surrounding brightness level.
Thus viewing ultrasound images on a TV monitor, or transparency film
images on a trans-illumination viewing box. is best achieved in a darkened
room. with the overall image brightness high. The darkened room allows
the viewer's eyes to dark adapt. The high brightness ensures that the minimal
contrast levels are perceived by the predominant cone vision. Fine image
detail is also best perceived by the cones under these conditions.
IIMAGE I
IMAGINr ~~GE
,- ~IEWING
I SCENE I 4 EYE/
DIRECT VIEWING PERCEPTION
III --
143
-- III III
-- III
III !!!!III!!!!!!!!
-== III
== III -- III
Figure 9.2 Portion of a test chart or scene, to assess the spatial resolution of a photo-
graphic or indeed electronic imaging process. Still smaller and narrower black bars and
white spaces are needed to provide still finer resolution tests
and black, but with a spatial separation between the peaks getting narrower
as one moves from left to right. The variation in brightness across the scene
is shown in figure 9.3(a). When the variation in the brightness across the
width of the resulting image is measured, for instance with a linear transla-
tion spot photometer, the result shown in figure 9.3(b) is found. In general
the ability of the imaging method to produce the full contrast falls off at
--. 1/N,-
I
(a)
(b)
Figure 9.3 (a) The variations in the luminance or light intensity from left to right
across a test scene. The maximum luminance is white and the minimum luminance is
black. N, the spatial frequency, which is the inverse of the distance from one white to
the next black strip, increases from left to right. (b) The variations in the luminance
from left to right across the image of the above test scene. As the spatial frequency
increases the dynamic range or the contrast in the image declines
144 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
(9.2)
M. = [i(max) - [,(min)
(9.3)
, [,(max) + [i(min)
The ratio of these two modulations is the modulation transfer function
M.
MTF=-' (9.4)
M,
M.T.F. 1
.5
o~------------------~-----
o .5
N
Figure 9.4 A possible dependence of the modulation transfer function (MTF) of an
imaging process on the spatial frequency (N)
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 145
screen over 20 cm x 20 cm, the MTF is well over 0.75. The smaller the
screen however the more condensed the lines and the lower the MTF.
The MTF is a useful objective measure of quality of an imaging process.
The actual value of MTF is a measure of the dynamic range of the image in
comparison with that of scene. The dependence of MTF on spatial fre-
quency allows one to objectively measure the spatial resolution of the image.
For instance the spatial separation (inverse of spatial frequency) at which the
MTF is 0.5 might be defined as the spatial resolution.
In most monochrome TV monitors the ratio of white brightness to black
brightness is about 250: 1. This dynamic range corresponds to 24 dB. An
analogue scan converter has a dynamic range of about 20 dB and there-
fore the TV monitor is adequate to display any latent image in the converter.
A digital scan converter with a 6-bit digitisation covers a dynamic range of
18 dB (see Appendix L). A photographic process accepts the TV display as
the scene to be imaged and must have a dynamic range of at least 24 dB to
be compatible with the TV display.
9.4 CAMERAS
In converting the image produced from the ultrasound scan from the
oscilloscope or TV monitor screen to a permanent photographic image, the
essential instrument is the camera. As shown in figure 9.5, the main features
of a camera are as follows:
(a) a light-proof box;
(b) the film on which the latent image is to be formed, positioned within
this box facing the lens system;
(c) the system oflenses accepts the light from the scene to be imaged and
focuses the image on the plane of the film. The lens system also has
a variable aperture, formed by the iris which controls the amount of
light collected. The focal length of the lens system may be varied to
accommodate objects in the scene near and far away and this control
helps to determine the size of the image formed at the film plane;
(d) interposed between the lenses and the film is the shutter, which is
opened to allow the light to fall on the film - the action of taking the
photograph.
Apart from the choice of film, which is discussed in section 9.5 there are
three variables or controls in the operation of a camera.
The first of these is the focusing control. In conventional ultrasound
imaging applications this is set when the camera is mounted in front of the
oscilloscope or TV monitor screen with the correct distance between camera
146 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
HT-TIGHT BOX
FOCUS CONTROL
L NS SYSTEM
SHUT ER
FILM
HOLDER
Figure 9.5 The main elements in a camera
lens and screen. The rigid form of the camera mount ensures that this
distance remains constant thereafter.
The second control variable is the so-called rstop or rnumber, which is
the diameter of the aperture expressed in numbers of lens focal lengths (j).
Thusj22 refers to an aperture diameter, 1/22 of the focal length, a very small
aperture.jI.S is an aperture 1/1.S ofI and is usually a large opening. Usually
rnumbers range thus 122, /16, Ill, fS, j5.6, j4, j2.S, Il.S. Choice of a large
aperture and hence a wide field of view, allows more light through to the
film. Conversely choice of a small aperture and so a narrow field of view
allows only a small amount of light through to the film.
All photographic films must receive an adequate light intensity or lumin-
ance for long enough, that is. an adequate exposure E, where
E=lx t (9.5)
in order to form the latent image. Here 1 is the incident luminance or light
brightness and t is the duration of exposure or exposure time. This latter is
the third control variable in the camera and can usually be set at a variety of
fractions of one second thus, 1/500, 1/250. 1/125, 1/160. 1/30, 1/15, I/S. 1/4,
1/2. 1/1. In many cameras it can also be opened and held open as long as
needed, a'nd then closed.
For a given source or scene luminance, the exposure may be controlled by
varying either the rnumber or the exposure time (the shutter speed). An
adequate exposure can be maintained by opening the iris and decreasing the
time or else by closing down the iris and increasing the time. In most cases
such variability is not very wide. For instance if the source is moving, then a
short exposure time only is allowable to prevent excessive blurring. In such
a case a wide exposure (small rnumber) and brief exposure time would be
applicable.
The specific choice of shutter speed (exposure time) and rnumber for
optimum image acquisition by the film depends on the particular film and
its speed property.
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 147
~~~~~~~PROTECTIVE LAYER
_ ~.. "'0 <:)-, •P'" C> '"
"-'" p~O'no() _0 ';.~1>:'p~;!I() f-EMULSION
I" .. v gO -0'"'' ADHESIVE
pOLYMER BASE
ANTI-HALATION
Figure 9.6 A section through an undeveloped single emulsion film showing the polymer
base. the adhesive layer. the emulsion. the supercoat protective layer and the anti-
halation and anti-curling back layer
back of the film base back into the emulsion. Thus it prevents the halo effect
on the image.
The emulsion has a number of ingredients as follows:
(a) The photosensitive grains of silver halide (mostly silver bromide
(AgBr), but with small amounts of silver chloride (AgCl) and silver iodide
(AgI)). The average size of these grains helps determine the sensitivity of the
emulsion to light. The larger the grains the more sensitive the film. because
then the incident light is more likely to encounter a grain. The distribution
of grain sizes determines the exposure latitude or range of tolerable ex-
posures for image retention. A wide range of grain sizes allows a wide
exposure latitude. The action oflight on the silver halide may be summarised,
AgBr+ 1ight~Ag + Br
This photochemical reaction has a quantum efficiency of 1 which means
that each quantum of incident light produces one atom of silver. Thus the
more quanta of light are incident (or the greater the luminance or brightness
of the light) the more atoms of silver are produced. The number of silver
atoms produced at each location in the emulsion is directly proportional to
148 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
the light luminance which fell on that part of the film. The atomic silver
therefore contains the latent image.
(b) Gelatin forms the medium in which the silver halide grains are dis-
tributed in suspension. It is transparent and spread as a layer on the base.
It prevents the reversal of the above photochemical reaction which would
undo the latent image storage. It can absorb water and swell. It can also
absorb the various chemicals needed for development and fixing.
(c) A range of chemical additives in the emulsion. Often there are certain
dyes or colour sensitisers which serve to broaden the range of wavelengths
oflight to which the emulsion can be made sensitive. This can be vital in that
the silver halide alone is maximally sensitive at wavelengths less than 525 .um
while the maximum sensitivity of the eye is at 550 .um. The action of the dye
is to absorb the light energy and transfer it to the silver halide. In the emulsion
there are also additives to prevent growth of bacteria and fungi, to improve
the storage properties of the film, to prevent the emulsion from becoming too
brittle when dry and generally to maintain the mechanical properties of the
emulsion. Finally, in the emulsion are halogen-absorbing chemicals such as
sodium nitrate which sequester the halogen product of the photochemical
reaction.
Development of the film to convert the latent image into a visible image
involves the treatment of the film with an aqueous solution of developer.
The developer is a reducing agent such as hydro quinone which converts
silver halides to silver. This reduction happens selectively, being much more
rapid in those crystals which had been exposed to light than in the unexposed
ones. Also present in the developing solution is an alkaline component
with high buffering capacity such as sodium carbonate or borax. Most de-
velopers function in an alkaline pH and since hydrogen ions are produced
by the development reactions, these must be mopped up by the buffer.
Another ingredient in the developer solution is the restrainer which holds
back the development of unexposed silver halide grains. Potassium bromide
acts in this way to maximise the difference in the rate of development of
exposed and unexposed grains. Absence of a restrainer results in fogging of
the film. In many film emulsions there is also some sodium sulphite which
retards the oxidation of the developing agent and so acts as a preserver.
A number of physical factors in the development process strongly affect
the time needed for adequate development. The higher the temperature the
more rapidly is the development achieved. The rate is approximately
doubled for a rise in temperature of lO°C. The developing solution must
first diffuse into the gelatin to reach the silver halide particles before de-
velopment can begin. Agitation of the solution relative to the film aids this
process and advances the development rate. The exact composition of the
solution is of maximum importance and it can deteriorate with age and
repeated use. As examples, absorption of oxygen from the air can cause
oxidation of the reducing agent, the bromide concentration can increase due
to evaporation of water and cause reduction of the development rate, the
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 149
pH may fall for similar reasons, etc. Care must therefore be taken to protect
the composition of the solution and replace it as needed.
After the appropriate period of development, the film is rinsed in clean
running water to remove any excess developer solution. It is then immersed
in a fixing solution-an aqueous solution of sodium thiosulphate. This
fixing agent forms soluble silver complexes with any unreduced silver halide.
on the film, i.e. the unexposed portions of the emulsion. This stage leaves the
film with varying amounts of opaque silver wherever light fell on the film,
with large amounts where the light had been intense and in general with
amounts in proportion to the incident light luminance. The opacity of the
film is greatest where the light had been most intense and so the film is a
negative representation or image of the scene originally viewed.
Either in the fixing bath or in a subsequent step it is desirable to harden
the remaining gelatin, containing the silver image. Alum is usually used as a
hardening agent. It provides aluminium ions which act to cross-link the
gelatin molecules.
Finally, the film must be thoroughly washed in running water to remove
all traces of the fixing chemicals and the film is then dried.
Automatic film processors, widely used for X-ray films, carry out the
development/rinsing/fixing/hardening/washing/drying process in about 90
seconds.
(9.6)
D
-Drn~_v
- - - - - - - - - - - -- - - - - - - - - - - - -
G
-~-~-
loglG E
Figure 9.8 The characteristic curve for a transparency film. A number of landmarks,
A, B, C, F and G are referred to in the text
The useful density range is a measure of the dynamic range of the film, the
span of greys from black to white. Clearly the wider this range is, the more
shades of grey can be accommodated. In a typical transparency the optical
density of the clear or white is practically zero while the density value of the
black is about 3. On the dB scale there is a 30 dB dynamic range. The steeper
the slope of the straight line part of the characteristic curve the greater the
contrast within the image. This slope is the gamma of the film and is defined in
equation (9.7)
(9.7)
film. It indicates the range of exposure that the film can tolerate and still
produce linear behaviour. Since any scene or TV display contains a range of
intensities, and the whole film is exposed for a fixed duration, different
regions of the film experience different exposures. All this range of exposures
must fall within the exposure latitude for proper photographic reproduction.
The composition and concentration of the emulsion determine the speed
of a film. A number of definitions of film speed are used. The ASA scale of
the American Standards Association is defined as 0.8/Em where Em is the
exposure value at a D level of 0.1 + basic fog. This is a measure of the inverse
of the exposure needed to bring the film to the threshold of the straight line
part of the characteristic curve. Low ASA numbers would indicate a slow
film. Clearly together with the gamma parameter, the ASA number en-
compasses much of the information in the characteristic curve.
A number of features of the development and processing stages can affect
the characteristic curve. The longer the development time the greater the
gamma. The higher the temperature of the developer the faster the speed and
the greater the gamma. Contamination of the developer solution can have
various effects on speed, gamma and basic fog.
The characteristic curve allows one to choose a film appropriate to a
particular imaging task. The film, the exposure conditions and the develop-
ment processes are parts of an integrated package. For optimum results they
must be matched to each other.
4 0 c:,C> 0 ()
o <>
. .. .,..-
0c;:l 0 0 0 Q ()
Q 0 o 0 0
•
.
Figure 9.9 The sequential steps in the development process for a reversal film
(9.8)
where Ii is the incident light luminance at 45° and Ir is the reflected luminance .
Figure 9.10 Light reflection from a photographic print. Ii is the incident luminance
and I, is the reflected luminance which is viewed by the eye
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 153
-
POSITIVE BLISTER
Figure 9.11 The main features in a Polaroid-Land film pack
154 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
NEGATIVE
hn"........n~...,n""'""";.,.n:::r--:::L:-n~n'-'=-d..-_DEVELOPI
Q-->--
NG
p p p p p P CHEMICALS
OSITIVE
Figure 9.12 A section through a diffusion-transfer (Polaroid) film during the de-
velopment phase
dissolved. The reduction of the exposed silver halide and the dissolution of
the unexposed crystals proceeds practically simultaneously. The silver ions
formed from the dissolution of the unexposed crystals encounter the reduc-
tion catalyst on the positive sheet in immediate contact and these are the
atoms which form the positive image. The atoms developed from the ex-
posed grains are reduced at the point of their formation and do not contribute
to the positive image-except to the extent that their presence reduces the
darkness of the positive image. Development starts from the instant that the
second tab is pulled through the rollers and the development time must be
accurately set for good results. The time needed drops as the ambient
temperature rises, and the specific dependence on room temperature is
supplied by the manufacturer.
Polaroid film comes in a wide range of speeds from ASA 200 to ASA
10000. The image has a dynamic range like a gloss print, of about t 5 dB.
t
Figure 9.13 A voltage varying with time, as displayed on an oscilloscope screen
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 155
(figure 9.14). The spectral response of the eye differs between the dark-
adapted and light-adapted eye and also differs from that of the photographic
film of choice. Therefore, an oscilloscope display which may seem perfectly
adequate for visual observation either in a darkened room or in ambient
light, may not at all be suitable for a given film. Often therefore if a con-
siderable amount of oscilloscope photography has to be done, it is advisable
to have a dedicated oscilloscope tube, with phosphor chosen to match the
SPECTRAL
SENSITIVITY
(RELATIVE)
film and used solely for photography, while another display with appropriate
phosphor is used for direct viewing.
(b) The oscilloscope display is formed by the sweeping of the electron
beam over the phosphor, as dictated by the variations in the voltage to be
displayed and by the ramp voltage of the time base. The intensity of the light
output from any point on the display is primarily dependent on the magni-
tude of the electron current in the tube but also on the dwell-time of the
writing electron beam on that point (a function of the time base ramp slope
and of the rate of change of the displayed voltage). In a given single sweep of
the display, there will be a range of luminances of the light spot output from
the screen.
(c) A further factor that affects the brightness of the display at any point
and at any instant after the first impact of the electron beam on the phosphor,
is the persistence of the light output from the phosphor. Usually, for photo-
graphy and in order to obtain clear images of rapidly changing voltages, a
phosphor with very short persistence is used. This is especially the case
when it is desired to capture on the image the variations in light intensity as
the sweep proceeds. As will be seen later, photography is also possible
from storage oscilloscopes, i.e. very long persistence displays.
(d) The phosphor in the tube also helps to determine the minimum light
spot size and hence the spatial resolution possible on the screen.
(e) For normal relaxed viewing, the oscilloscope display sweep is trig-
gered by some feature of the voltage signal to be viewed - if that voltage is
156 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
Broadly there are three main ways in which grey-scale images are obtained
on films or prints: first, one uses a normal short persistence oscilloscope dis-
play with the camera shutter open for the duration of the scan; the second
is photography of the TV monitor display of the grey-scale image stored in
a scan converter; in the third method, the image brightness patterns are
guided line by line to the print paper emulsion by means of a fibre optic
array and a positive print is quickly developed to yield immediate hard
copy prints.
In the open shutter technique, the ultrasound echo amplitudes modulate
the intensity of the writing spot in a conventional short-persistence oscillo-
scope while the location of the writing sweep is determined by the orientation
of the ultrasound beam and the positioning of the bright spots along the
sweep is set by the pulse echo return times and the average speed ofpropaga-
tion. Thus as the probe is scanned over the skin, a B-mode image is con-
structed but in this case it is stored on the photographic film which is exposed
to the display throughout the scan. The intensity of the picture to be thus
imaged is controlled by the echo amplitude and the set basic oscilloscope
intensity while the camera aperture or f-number controls the amount of this
intensity reaching the film. The time taken by the operator to carry out the
complete scan and the rate of swing of the beam through each part of the
tissues sets the other part of the film exposure-the duration of the exposure.
Since there are so many controls it is essential to obtain an image for
inspection as soon as possible and before proceeding to obtain the next
cross-sectional image. Instant photography is thus essential in this technique.
Photography of the display on the TV monitor from the intermediate image
stored in the scan converter, rests on many of the basic principles described
in section 9.9. Some additional ideas should be borne in mind however. The
TV display is repetitively built up in the raster scanning fashion, and it takes
1/25th of a second for a complete picture. Exposure times less than this
yield an incomplete image. Exposure times integral numbers of times 1/25 (s),
produce even integration of the exposure over the image and may allow the
use of reduced .f~number. Other values of exposure time yield uneven in-
tegration of the image and therefore some parts of it brighter than other
parts.
In a darkened room the TV monitor display has a brightness dynamic
range of some 24 dB. An analogue scan converter has a dynamic range of
about 18 dB and so the monitor contrast setting control must be used to
reduce the display contrast in order to match the data from the scan con-
verter. Some digital scan converters have a wider dynamic range and are
more closely compatible with the monitor. Transparency film can encompass
the monitor output dynamic range but prints such as those from instant
158 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
techniques such as Polaroid can not. In this latter case some compromise
may often have to be made resulting in the neglect of some echo variations
either at the low end or at the high end. This compromise can be made with
the TV monitor controls but may not be visually the most pleasing image.
It becomes a problem in scanning, when a satisfactory visual image is ob-
tained on the screen but then it must be modified before the photographic
step. The best solution is to have a separate dedicated monitor for pho-
tography. This can be chosen to have the appropriate phosphor for the film
of choice and can have a smaller screen to suit the available cameras.
Since the range of luminances in a TV display can vary from one scan to
the next, it may be necessary to modify the aperture and/or the shutter
speed, repeatedly during an examination. Some machines have automatic
light meters in the cameras which measure the light coming towards the
film at a number of spots and which use this information to electronically set
the shutter opening duration. A more dependable photography can be
achieved in this way.
In the diagnostic examination of ultrasound images some clinicians prefer
a negative image (black echo data on white background) while others prefer
a positive image (white echo information on a black background). A positive
or negative transparency can be prepared, or a positive or negative print can
be made along the lines previously described. But many TV systems allow
the signals to be reversed electronically, as shown in figure I.3(b). The
picture part of the video signal for each line is inverted electronically to
produce the negative from the positive or vice versa. Another ready possi-
bility is currently available from some instant Polaroid films, and this is that
both the positive and negative images emerge in a form that can be retained
and stored.
The third main way of obtaining printed pictures of the ultrasound images-
so-called hard copies-is shown schematically in figure 9.15. The basic
display device is a specialised cathode-ray tube such as is shown in more
detail in figure 9.16. It has a very narrow horizontal display screen and no
vertical deflection plates. It displays one line of video at a time. The light
output from the face of the screen is conducted along a linear array of fibre
optics and directed on to the emulsion of a rapid development photographic
paper. The paper is moved past the tip of the fibre optic array in a stepped
manner and at each step the specific line of the raster is repeated often enough
to accumulate an adequate exposure of the photographic paper. The line
synchronisation pulses in the composite video signal control the stepping
motion of the paper and the frame synchronisation signals control the
further carriage of paper into the rapid development process. In most cases a
single line of the video provides enough luminance input for exposure of the
emulsion and so the whole exposure and development process can take less
than 30 seconds.
The print output from this technique can, depending on the video signal
input, be either a positive or negative image. The overall contrast- the range
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 159
COMPOSITE
VIDEO SIGNAL
CONTROL
ELECTRON ICS
DEVELOP
&'PRINT
VIDEO
STEPPING
MOTOR
C. R. T.
'-----//
LINEAR ARRAY
FIBRE OPTIC
LIGHT GUIDE
Figure 9.15 A line printer system for producing a paper print of an electronic image,
TV raster line by TV raster line
SIDE FRONT
Figure 9.16 A special-purpose single line display oscilloscope for line-by-Iine photogra-
phy
of grey shades from black to white-is less than that achieved with trans-
parencies and less than are apparent on the TV monitor. But the speed and
ease of operation are major advantages.
An imaging technique very similar to the above is also commonly used for
recording M-mode studies of the heart and related structures as discussed in
chapter 5. In that case the linear display in the specialised CRT screen at each
instant is the B-mode representation of the echo train from the structures
along the axis of the ultrasound beam at that instant. The photographic
paper is moved along at a steady rate and the M-mode display from the
moving structures are imprinted on the paper. Two main types of paper are
used in this application. A rapidly developed paper with a range of grey
tones as described above can be used and the images stored on it convey the
motion information and very useful information about the echo-producing
texture of the structures. This latter is an expanding area of interest in
160 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
cardiac ultrasound. The second paper type is one which is capable of photo-
development. After the initial exposure as described above the paper is
passed under an ultraviolet light which activates the development process in
the emulsion already on the paper. The development proceeds to completion
and the resulting image has limited contrast, usually on a yellow or buff
background. The whole process is dry and very fast. Subsequent exposure to
daylight and normal artificial lighting results in very little image fading.
The following electronic image storage systems are coming into increasing
availability and use: video tape recorders, magnetic disc memory and com-
puter memory devices. These devices require the image to be supplied to
them in an electrical form, either analogue or digital, and usually in a
rastered sampled fashion just like the video signal which drives a TV monitor.
The image is first converted into a set of lines each yielding a time-varying
video voltage, each video line following the previous one. On the 625-line
standard the total image takes 1/25 s and is segmented into 625 time sections.
In the digital case this 1/25 s of signal is sampled and digitised, for instance
106 times, at equal intervals throughout, and so the picture then consists of
106 separate numbers in known orderly sequence (see Appendix K).
The video tape recorder (VTR) is capable of storing an image in either of
these forms, analogue or digital. The storage medium is a layer of ferro-
magnetic material such as a metal oxide which is spread on a polymer base
(see figure 9.17). In the recording or storing mode this tape is moved at a
steady speed past the air gap of the electromagnet. This is energised by a
current varying as the video signal to be recorded. Thus the particles of the
magnetic material are magnetised to a degree dependent on the signal
energising the recording head electromagnet. The degree of magnetisation
of the particles along the tape thus carries the signal to be stored. In the
VIDEO
SIGNAL
MAGNETIC OXIDE
.z::zLoor:~~m~~:zCOATI NG
________ Q--POLYMER BASE
TAPE MOTION
Figure 9.17 Simplified diagram of the process for magnetic recording of electronic
signals
PERMANENT RECORDS OF ULTRASOUND EXAMINATIONS 161
9.14 BIBLIOGRAPHY
Figure 10.1 A PPI-mode image of the prostate (top) , obtained with probe in the anal
passage
----+-------') 35J~BE
(a)
______________-__ ~UTER
SHEATH
(b)
Figure 10.2 Transducer probes used in PPI-mode scanning: (a) A single transducer
rotating within a fixed sheath. (b) An array laid out along the circumference of the probe
image storage or display. In this case a single parameter, the angle, is suffi-
cient to describe the beam orientation at any location.
The main application of PPI-mode scanners is transrectal examination of
the prostate, bladder and contiguous structures. Some applications have
been reported in the examination of cardiac structures from a vantage point
in the oesophagus or in the trachea. With the development of miniaturised
probes and improvements in scanned array technology it is likely that such
applications will increase in the future.
The C-mode scan is also based on the pulse echo principle. The C-mode
image is an acoustic image of a cross-section through the tissues, at right
angles to the conventional B-mode sections. Thus, a C-mode cross-section
would be normal to the ultrasound beam axis.
To build up such an image three novel steps must be taken thus:
(a) In the signal processing stage, the echo train is range-gated, to allow
through only the echo signals from a fixed depth or fixed distance from the
transducer face. This brief gated echo signal is then used to generate a
bright-up signal in a scan converter.
(b) The probe is held in fixed orientation and is moved in a ziz-zag
motion on the skin over the tissue region of interest. This is illustrated in
figure 10.3. Since the plane in which the motion of the probe occurs must be
held fixed to ensure that the image is of a flat plane defined by the depth of
the range gate, it is desirable to use a water bath over the skin and to move
the probe in the open surface of the water. The zig-zag motion of the probe
SPECIAL INSTRUMENTS AND NEW TOPICS 167
CONSTANT
DEPTH
CROSS -
SECTION
Figure 10.3 The build-up of a C-mode or constant depth-mode scan involves the
zig-zag painting motion of the probe over the skin surface
is to ensure that all parts of the tissue section of interest are interrogated at
least once by the beam.
(c) Both the X and Y spatial dimension of each feature of the image are
set by the X and Y positions of the probe. Registration involves the genera-
tion of electrical signals proportional to the two Cartesian co-ordinates of
the probe, and the use of these voltages to produce X and Y deflections in
the display devices. The image can be either bistable or grey scaled depending
on the imaging modality available - bistable in a storage oscilloscope, grey
scaled in a scan converter/TV monitor system.
If the region to be imaged is large it can take a long time to 'paint' the full
picture. If the probe motion is done manually, parts can be missed. But if a
water bath is used the scanning action can be readily automated in contrast
to conventional contact B-mode imaging.
The image acquired is of a single cut at a fixed depth. To obtain images of
sections at other depths the range gate must be reset and the zig-zag scanning
motion repeated.
The possibility of automating such scanning, promises a growing number
of applications for this technique. This possibility is heightened by the intro-
duction of linear arrays with dynamic focussing capability. In such an
instrument, one movement only of the linear array probe would be needed
to complete a scan, and the dynamic focus could be set to the sample depth.
Indeed much sharper focussing than is tolerable in B-mode imaging would
then be possible. Furthermore, the introduction of computer techniques
with intermediate storage of images in a magnetic disc buffer and rapid
168 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
~C TOR 0)CTOR
\2)' , 2r
, ,
, ,
,
,,
, , , TISS E
,, ,
,
!J
, ,
'~ I
,,
1MAGE PLANE'
(a) (b)
through the tissues is due to both the attenuation coefficient of the tissue
types and the length of the path through those tissues as shown in figure
10.5. Thus the total attenuation AT' in the path is given by (equation 10.1):
A T =/11 Ll +/12 L 2 +/13 L3 ...
(10.1)
m
the sum of all the constituent attenuations. If one of the tissue types in a
vector is highly attenuating then all of the pixels in that vector will receive
a high attenuation score. But when any slightly attenuating tissues are
approached from other angles these pixel memory locations receive only
small contributions. Equally when the highly attenuating tissue is ap-
proached from other angles its pixels continue to receive large contributions.
Then when the final averaging is done the pixels mapped on to highly
attenuating tissues still retain high values and the reverse holds for the
pixels on to which are mapped the low attenuation tissues.
2 3 4 5
c,
(10.2)
PROBE
IjPROBE
(a) (b)
Figure 10.6 Two alternative water-bath immersion techniques used for breast scanning
172 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
the focal region of the beam must be further from the transducer face than
in contact scanning in order to fall within the breast tissues. For correct
electronic registration, the water bath must have a speed of propagation
equal to the average speed of propagation in the breast tissue. This speed
may not be quite 1540 m/s as is used for general soft tissues, but whatever
the value that is optimum, it can be set for the bath by making this an
aqueous sodium chloride solution or an ethyl alcohol/water solution as
described in section 10.11. The bath temperature should be set for patient
comfort and for correct propagation speed. In the signal processing it is
important to initiate the time gain compensation (TGC) slope at the skin
surface echo at each position of the beam. This is critical in that in general
the skin line is at various distances from the probe at different stages of a
scan and unless the TGC is set as mentioned, echoes from the same depth
into the tissues will be amplified or compensated to different extents. A
quite erroneous texture would appear in the final image.
Another problem arises in breast scanning when the situation of figure
10.7 occurs -severe refraction at the sides of the breast. This can result in
failure to be able to interrogate the tissue in the outer perimeter of the breast,
giving an incomplete image. It can also result in artifactual registration of
structures in the breast. Therefore it is important to be able to achieve ex-
tensive compounding of the motion of the probe during the scan. However,
because the refraction artifacts can give valuable clues as to whether a
structure within the tissues is cystic or not, linear scanning is also necessary
and helpful.
A technique similar to that of figure 10.6(b) is commonly used also for
scanning the thyroid, except that in this case the water bath is usually a thin
polythene bag which can readily adapt to the shape of the neck when filled
with water.
Figure 10.7 Refraction can occur in water bath scanning of the breast
H PROBE
HOLDER
, :
,
-:-, ~, - ,
" PROBE
Figure 10.8 A transducer probe with a hole through the axis designed for needle
biopsy work
Specially adapted linear array transducers have also been made for needle
guidance. A needle hole through some of the crystals or just beside the array
serves to perform the task.
Another adaptation of transducer array technology, the concentric array
transducer. promises to allow a wide range of degrees of focussing as well as
ranges of focussing in a cylindrical beam. The face of such a transducer is
shown in figure 10.9. By activating the set of transducers in different phased
sequences, the distance to the focal zone can be controlled as can the degree
of focus. Refer to multi-element linear array beam focussing in chapter 3.
Among the most recent developments of array technology and the related
instrumentation is the two-dimensional matrix such as is shown in figure
10.10. In such a rectangular matrix. any row or column of crystals can be
activated at any stage to define a scan plane. Switching between different
sets of crystals is done electronically. Sets of images from a series of parallel
planes can be quickly acquired. Indeed real-time or dynamic flick-through
viewing of a set of neighbouring static images can be a feature. The same
procedure can be carried out in planes perpendicular to those previously
174 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
Figure 10.9 A four-element annular array or zone plate transducer. The elements
have equal front surface areas
DDDDD
DDDDD
DDDDD
DDDDD
DDDDD
Figure 10.10 A possible two-dimensional array of transducer elements
(a) (b)
Figure 10.11 In the build-up of an image of any general cross-section (b) through the
tissues, by computer, the images of all the parallel slices in the three principal directions
(a) must first be acquired
I
I
~ ~~ / BJH
Figure 10.12 The circumferential array of transducers within a water bath, of the
'Octo son ' scanner
176 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
plastic is achieved with gel or oil. The array of transducers can be made to
automatically execute a number of motions thus: the whole gantry can move
linearly up and down the water bath lengthwise along the patient (per-
pendicular to the paper in figure 10.12); the whole gantry can swing about
the diameter of the circle, thereby interrogating different angular sections
through the body; the array can be rotated about the centre of the circle of
the array, thereby allowing the scanning action of the array, in any section,
to be compound in that the approach of the active beam to any structure in
the body varies during the scan and so perpendicular incidence can more
likely be approximated. The control of the motorised transducer array must
be computerised and also the measurement of the active beam orientation
for the image reconstruction is complex and is also computer processed. A
scan consists of the sequential activation of the transducers coupled with
their rotation.
Clearly, the main automatic element in this scanner is in the transducer
motion. Also the range of motions of the transducer array shown in figure
10.13, allows a wide number of angles of approach to any tissue in the part
of the body to be examined. Most tissues are therefore accessible to the
instrument. Furthermore since the patient lies on the water bath and the
access into the patient is from the underside, the problem of gas in the bowels
is greatly reduced since this gas has a tendency to rise when it is free to do so.
PATIENT
Figure 10.13 The range of motions of the circumferential array in the scanner of
figure 10. 12
Duplex scanners are devices that have a dual capability, usually B-mode
imaging and a Doppler blood flow detector in the same unit. The basic idea
is to first obtain a B-mode image (usually a real-time image) of a blood
vessel, for example a longitudinal view, and to use this image to position
and orient the Doppler probe. A line representing the path of the beam from
the Doppler unit can be inscribed on the B-mode image, so that the angle
of incidence of this beam relative to the flowing blood cells can be measured
SPECIAL INSTRUMENTS AND NEW TOPICS 177
directly. The diameter of the vessel can also be measured from the image
and hence the data needed for quantitative blood flow measurements are
available.
If the Doppler instrument is a pulsed unit, it is possible to use the same
transducer for both B-mode and Doppler applications.
2 3
0
0 0
0
0
0
0
Figure 10.15 A speckled pattern of greys such as might be found in the image of the
parenchymal tissue of an organ
Within such a region of interest one can measure the distribution of optical
densities (transmission or reflection) and obtain a histogram of this distribu-
tion as shown in figure 10.16. The histogram plots the number of occurrences
of each density (or luminance in the TV display) in the region. Another
possibility is to continuously measure the optical density along various lines
across the region of interest. Such a plot. as shown in figure 10. I7 . indicates
the range of densities encountered but also the lengths of the features of the
pattern. The latter would indicate the graininess of the image . Comparison
between such area histograms or optical density functions along lines of
interest related to different tissues . might be expected to reveal clear points
NUMBER
OF
CASES
1 2 3 4 5 6 7
8 109
WHITE BLACK
OPTICAL DENSITY
Figure 10.16 A possible histogram of the optical densities within a region of an image
SPECIAL INSTRUMENTS AND NEW TOPICS 179
BLACK--
OPTICAL
DENSITY
WHITE- _L...-_ _ _ _ _ _ _ _ _ __
DISTANCE ALONG LINE
Figure 10.17 A possible variation of the optical density along a line of interest across
an image
1650
c (m/s)
160
150
20't:
(a) 5 10 15
%NaCi
1650
c (m/s)
1600
1550
145c~--------~----------~-
(b) 10 20
% ETHYL ALCOHOL
180 (kg/ml)
1.
.8
.6
.4
.2
o r . . . . , I
2 3 4 5 6 7
f (MHz)
Figure 10.19 The logarithmic attenuation coefficient in 3% agar/water gel, doped
with different concentrations of carbon powder as shown, at diagnostic ultrasound
frequencies. The curves are similar to those for soft tissues as shown in figure 2.16 and
by choosing the concentration of carbon powder specific attenuation levels may be
designed into the medium
182 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
10.13 BIBLIOGRAPHY
Brascho, D. J. and Shawker, T. H., Abdominal Ultrasound in the Cancer Patient, John
Wiley, New York, 1980
Edmonds, P. D. (Ed.), Ultrasonics, Academic Press, New York, 1981
Evans, K. T. and Gravelle, I. H., Mammography, Thermography and Ultrasonography
in Breast Disease, Butterworths, London, 1973
Goldberg, B. B. (Ed.), Abdominal Grey Scale Ultrasonography, John Wiley, New York,
1977
Harrison, D. C. et al. (Eds), Cardiovascular Imaging and Image Processing: Theory and
Practice-1975, Society of Photo-Optical Instrumentation Engineers, Palos Verdes
Estates, Ca, 1975
Hazzard, D. G. and Litz, M. L., Biological Effects and Characterizations oj Ultrasound
Sources, Castle House Publications Ltd, 1979
Hildebrand, B. P. and Brenden, B. B., An Introduction to Acoustical Holography,
Plenum Press, New York, 1972
Hill, C. R. and Alvisi, C. (Eds), Investigative Ultrasonology. 1: Technical Advances,
Pitman Medical, Tunbridge Wells, Kent, 1980
Holm, H. H. and Kristensen, P., Ultrasonically Guided Puncture Technique, W. B.
Saunders Co., Philadelphia, 1981
James, A. E. Jr. (Ed.), Radiological Clinics ojNorth America, Vol. 18-1: Symposium on
Advances in Ultrasonology, W. B. Saunders Co., Philadelphia, 1980
SPECIAL INSTRUMENTS AND NEW TOPICS 183
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
Millner, R. (Ed.), Ultrasound Interaction in Biology and Medicine, Plenum Press, New
York, 1983
Preston, K. et al. (Eds), Medical Imaging Techniques: a Comparison, Plenum Press,
New York, 1979
Rhyne, T. L., Acoustic Instrumentation and Characterisation of Lung Tissue, Research
Studies Press, Forest Grove, Or, 1977
Rose, J. L. and Goldberg, B. B., Basic Physics in Diagnostic Ultrasound, John Wiley,
New York, 1979
Rosenfield, A. T., Genitourinary Ultrasonography, Churchill Livingstone, Edinburgh,
1979
Stroke, G. W. et al. (Eds), Ultrasonic Imaging and Holography: Medical, Sonar and
Optical Applications, Plenum Press, New York, 1974
Thijssen, J. M. (Ed.), Ultrasonic Tissue Characterization: Clinical Achievements and
Technological Potentials, Stafleu's Scientific Publishing Co., Brussels, 1980
de Vlieger, M. et al. (Eds), Handbook of Clinical Ultrasound, John Wiley, New York,
1978
Wade, G. (Ed.), Acoustic Imaging: Cameras, Microscopes, Phased Arrays and Holo-
graphic Systems, Plenum Press, New York, 1976
Wells, P. N. T. and Woodcock, J. P., Computers in Ultrasonic Diagnostics, Research
Studies Press, Forest Grove, Or, 1977
Wells, P. N. T. and Ziskin, M., New Techniques and Instrumentation in Ultrasono-
graphy, Churchill Livingstone, Edinburgh, 1980
Woodcock, J. P., Ultrasonics, Adam Hilger Ltd, Bristol, 1979
Annual Reviews
Kurjak, A. (Ed.), Progress in Medical Ultrasound: Reviews and Comments, Excerpta
Medica, Amsterdam, annually from 1980
Linzer, M. (Ed.), Ultrasonic Tissue Characterization, U.S. National Bureau of Stand-
ards, Washington, annually from 1976
White, D. N. (Ed.), Recent Advances in Ultrasound in Biomedicine, Research Studies
Press, Forest Grove, Or, annually from 1977
White, D. N. (Ed.), Ultrasound in Medicine, Plenum Press, New York, annually from
1976
Various Editors, Acoustical Imaging, Plenum Press, New York, annually from 1969
11 Safety of Diagnostic Ultrasound
1d
INTENSITY
(W/m2)
10'
10 1d 10'
DURATION (5)
Figure 11.1 The threshold conditions of ultrasound intensity and irradiation duration
to cause damage to mammalian brain tissue
Inhibition of the action potentials of muscle tissue in vitro has been found
to result from exposure to ultrasound intensity levels near 1.5 x 104 W/m2
at 1 MHz for 5 min. Similar intensity levels at 3 MHz have been shown to
change the calcium transport properties of muscle cell membranes. Other
alterations in membrane permeability have also been noted to result from
intensity levels of about 6 x 103 W/m2.
Damage to the foetus in utero, caused by ultrasound, has been investigated
in a number of animals including mice and rats. In one such study, rat
embryos were subjected to 2.25 MHz ultrasound of intensities in the range
10-2 x 10 3 W/m2 through an incision in the maternal skin and abdominal
wall. Five minute treatment durations were applied on the 3rd, 5th, 6th and
15th days of gestation. The foetuses treated early in pregnancy weighed less
than control cases and the abortion rate was also greater in the treated cases.
However no abnormalities in the neonatal rats which had been thus treated,
were found when these latter were compared with untreated controls. Studies
on pregnant mice, using 1 MHz ultrasound at 5 x 10 3 W/m2 for 3-min
SAFETY OF DIAGNOSTIC ULTRASOUND 189
treatment periods, resulted in significant decrease in the rates of survival of
the foetuses in comparison with untreated controls .
Figure 11.2 summarises the conditions of intensity and duration which
have been observed to cause ill effects in mammalian tissues. Below 10 3
W/m2 no ill effects have been found regardless of the duration. Furthermore
if the product of intensity and duration of exposure to ultrasound is less
than 5 x 10 5 J/m2 , no undesirable side effects have been demonstrated.
10'
IN TE NSI TY
( W / m l)
\
\
ld
\
. r;:'!" J~9J~~l,-[::.R..L.I!'1 I.T. } .. _. _~ y . . _. ~ 5. _
\
\
10
Figure 11.2 The minimum levels of intensity and duration of ultrasound , at which
effects in mammalian tissues have been observed or postulated . The effects cited are
(\) paralysis, (2) foetal weight reduction , (3) postpartum mortality, (4) altered mitotic
rates and (5) suspected foetal abnormalities. The 5 x 10 5 11m2 exposure line is shown
as is also the 10 3 W1m2 maximum reported intensity of a cw Doppler beam (after Hill)
11.4 EPIDEMIOLOGY
Apart from the more macroscopic ill effects discussed above, the possibility
exists that more subtle effects may result from exposure to ultrasound. Such
effects might remain latent only to become manifest months or years after
the original exposure. This type of possibility raises worries especially in
relation to the many uses of ultrasound during pregnancy to study the
foetus. At the present time many millions of pregnant women are examined
with ultrasound at least once during pregnancy, each year. At least half of
these are examined more than once in the pregnancy. Furthermore the
availability of pulse-echo and Doppler devices is increasing rapidly from
one year to the next and so the numbers of pregnant women being examined
is also rapidly growing. In addition the number of clinical situations in
which ultrasound is the indicated investigative modality is also growing. The
possible existence of a sub-group of the population sensitive to ultrasound
should also be borne in mind.
The requisite large-scale epidemiological search for any such subtle effects
of diagnostic ultrasound has not yet been carried out. Such a study would
be of great value in quantifying the risks and safety of diagnostic ultrasound
as used in clinical situations.
In an early limited study carried out in New York, Glasgow and Lund
(Sweden), abnormalities in the off-spring of some 1048 pregnancies which
had been examined ultrasonically, were studied. Table 11.1 summarises the
results of the study. An overall abnormality rate of2.7% was observed. This
rate compares favourably with the average abnormality rate of some 4.8%
Totals 29 2.7
SAFETY OF DIAGNOSTIC ULTRASOUND 191
found in another survey of some 63000 single births in the United States.
The conclusion of that study was that diagnostic ultrasound did not appear
to present a hazard to the foetus.
heart with ultrasound for up to some hours during labour. Such long-term
monitoring could conceivably elevate the energy concentration in the beam
to the vicinity of 5 x 10 5 11m 2 . Some care is needed in this application.
The attenuation of the ultrasound wave as it traverses the tissues also
introduces a safety factor. If a specific target tissue or organ is some 5 cm
deep below the skin, the beam is attenuated by 5 dB or more before it en-
counters the organ of interest. For example 6 dB corresponds to a reduction
of intensity by a factor of 4. The greater the attenuation coefficient of the
intervening tissues, the greater the reduction of the ultrasound energy
dosage to the target tissue.
Other 'good house-keeping' measures should also be adopted in practice
in order to minimise the dose to the tissues. The lowest output ultrasound
power, commensurate with obtaining a good image of the required flow
information from Doppler studies, should always be used. Many instruments
allow the output or transmitted power to be reduced electronically. Un-
necessary scans should be avoided and repeat scanning minimised. The
development of tissue-equivalent phantoms for use in the process of learning
how to scan, can also minimise unnecessary scanning of humans. When not
scanning and building up the images, the transducer should be lifted away
from contact with the patient's skin. If the pulse repetition frequency (prf)
of a pulse-echo instrument can be varied, then it should be set to the lowest
value needed for adequate imaging. The overall duration of the ultrasound
examination should be kept as short as possible, and training and experience
help in this respect. When ultrasound is used in the vicinity of the eyes, where
there is very little attenuation in the tissue path before the sensitive retina,
care should be taken to avoid intense or focussed beams and to minimise the
duration of the examination.
11.7 BIBLIOGRAPHY
Dunn, F. and O'Brien, W. D. Jr. (Eds), Ultrasonic Biophysics, Dowden, Hutchinson &
Ross Inc., Stroudsburg, Pa, 1976
Edmonds, P. D. (Ed.), Ultrasonics, Academic Press, New York, 1981
Hazzard, D. G. and Litz, M. L., Biological Effects and Characterization of Ultrasound
Sources, Castle House Publications Ltd, 1979
Hill, C. R., Chapter on Ultrasound in Manual on Health Aspects of Exposure to Non-
ionizing Radiation, World Health Organization, Geneva, 1977
Hussey, M., Diagnostic Ultrasound: an Introduction to the Interactions between Ultra-
sound and Biological Tissues, Blackie & Son, Glasgow, 1975
Kremkau, F. W., Diagnostic Ultrasound: Physical Principles and Exercises, Grune &
Stratton, New York, 1980
Linzer, M. (Ed.), Ultrasonic Tissue Characterization, U.S. National Bureau of Stand-
ards, Washington (annual volume)
McDicken, W. N., Diagnostic Ultrasonics: Principles and Use of Instruments, 2nd edn,
John Wiley, New York, 1981
SAFETY OF DIAGNOSTIC ULTRASOUND 193
Rose, J. L. and Goldberg, B. B., Basic Physics in Diagnostic Ultrasound. John Wiley,
New York, 1979
Thompson, H. E. and Bernstine, R. L., Diagnostic Ultrasound in Clinical Obstetrics and
Gynecology, John Wiley, New York, 1978
de Vlieger, M., White, D. N. and McCready, V. R., Ultrasonics in Medicine, Excerpta
Medica, Amsterdam, 1974
de Vlieger, M. et al. (Eds), Handbook of Clinical Ultrasound, John Wiley, New York,
1978
Wells, P. N. T., Biomedical Ultrasonics, Academic Press, London, 1977
Woodcock, J. P., Ultrasonics, Adam Hilger Ltd, Bristol, 1979
Appendix A
EXPONENTIAL DECAY
(A.I)
'. -- -- - - - --
:,7"
, Jo
,
:·7(·71.
, 0
)
x
Figure A.I The exponential decay of the dependent variable y as the independent
variable x increases. In each characteristic increase in x, xc' y falls by a factor of about
0.7
Appendix B
LOGARITHMS
F(N)
Figure C.I The force F on a spring is directly proportional to the extension x of the
spring. The slope of the graph, C, is called the spring constant. The area under the
graph up to a given extension, shown cross-hatched, is the work done in stretching the
spring and also the energy stored in the spring
198 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
Figure C.2 A mass M, acted upon by a force F horizontally along the table, is pre-
vented from being accelerated by an oppositely-directed frictional force, Ff
(a)
(b)
(c)
HEAT
ELECTRICITY
(a) D.C.
A simple D.C. circuit is shown in figure E.l. On the left is a source of electrical
current and on the right is a resistor which tends to reduce the current flow.
The current flowing consists of electrons, tiny negatively-charged particles,
moving through the wires of the circuit. The current flowing is the amount of
electrical charge flowing in each second, arid is measured in units of amperes
(A). The source of current, which might be a battery, is characterised by the
electrical pressure, called the potential difference, E, which it develops. For
a particular potential difference, E, and a given circuit resistor of resistance,
R, the amount of current, I, which flows is determined by Ohm's law shown
in equation (E.l)
I=E/R (E.1)
Potential difference is measured in volts (V), while resistance is measured in
Ohms (Q).
APPENDIX E: ELECTRICITY 203
Every electrical appliance has a value of resistance. A lamp or fire element,
a motor or cooker, each a characteristic value of resistance.
The current flowing constantly carries energy to the resistive load. The
amount of energy carried each second is the power delivered to the re-
sistor. The power, P, in watts (W) is given by equation (E.2):
P=EI
=R PeW) (E.2)
If the current flows for some length of time, t, then the amount of energy,
EE' in joules delivered to the load is the product of power and the time taken,
indicated by equation (E.3):
EE=Pt
=Elt (E.3)
=RPt
The flow of current in a wire is also associated with magnetism. F or instance,
a coil of wire caIled a solenoid, as shown in figure E.2, carrying current, has
a magnetic field which is equivalent to that of a bar magnet. The strength of
the magnetic field is proportional to the current I. The polarity of the field,
which end of the equivalent magnet is north and which is south, depends on
the direction of flow of the current.
N s
Figure E.2 A solenoid carrying an electrical current acts like a bar magnet
(b) A.C.
e(V) E:f!1?X.
(a)
. p'
I(A)~.q(s)
T(5) ,
(b)
p(W)F~T\~
(c)
t(s)
Figure E.3 (a) The sinusoidal variation of voltage with time in an A.C. voltage source.
(b) The A.C. current which flows in a resistive circuit when the voltage in (a) is applied
across it. (c) The instantaneous power delivered to the resistor in this A.C. circuit
i=elR
= (Emaxl R) sin wt (E.7)
= I max sin wt
where
(E.8)
As shown in figure E.3(b), the current varies in step with the voltage.
Therefore, for half of the time the current is moving in one direction in the
circuit while for the other half of the time it is moving in the opposite direction.
Nevertheless, power, p, is delivered to the resistive load as indicated by the
following equation:
p=ei
(E.9)
APPENDIX E: ELECTRICITY 205
As shown in figure E.3(a), the power, the rate at which energy is being
delivered to the resistor, is constantly changing. The average power, P AV' a
constant power which would deliver the same amount of energy as the A.C.
power, is given by equation (E.IO):
P _ Emax Imax
AV- 2
Emax Imax
(E.lO)
(E.II)
ELECTRONICS
(a)
(b)
(c) i~
t
Figure F.l The rectifying action of a diode in an A.C. circuit. (a) The resistive circuit
with the diode in series with the resistor. (b) The sinusoidal A.C. supply voltage. (c) The
current flows only during the positive or forward phases of the A.C. voltage. Zero
current flows during the negative phases
(a)
~
base
Ollector
eml.tt er
eout
(b)
(c)
~OU\
Figure F.2 (a) The usual symbolic representation for a transistor. (b) A simple circuit
for a common-emitter transistor amplifier. ein is the input signal voltage and eOU ! is the
output voltage. (c) A schematic or functional representation of the amplifier as a four-
terminal device. ein is the input voltage, eOU ! is the output voltage and A, the ratio of
these two voltages, is the gain or amplification factor of the amplifier
208 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
CATHODE-RAY OSCILLOSCOPE
SCREEN
.. -
Located between the cathode and this first anode is a metallic screen with
multiple perforations, the so-called control grid. Varying the fairly small
voltage of this grid relative to the cathode varies the flow of electrons to the
anode and in turn controls the brightness of the light produced at the screen.
Normally there is an external connection or input to this grid which is called
the 'Brightness Modulation' or Z input of the osciIIoscope.
The first anode in the electron gun has a perforation in its centre. The
electrons are drawn from the cathode at a high speed towards the anode.
Some of these electrons manage to pass through the hole in the centre of the
anode of the gun. They continue to be accelerated towards the screen by a
final anode which is evaporated on to the inside of the phosphor of the
screen. This anode is at a stiII higher voltage relative to the cathode. Thus, the
electron gun focusses the electrons into a sharp collimated beam which is
then drawn to the screen.
Between the electron gun and the screen, there are located two sets of
electron-beam deflection plates, one set arranged horizontally and the other
set arranged vertically with the electron beam passing between the two pairs
of plates. When a voltage is impressed between the two horizontal plates,
with the upper plate positive and lower plate negative, the beam of electrons
is repelled from the lower plate and attracted towards the upper plate. Con-
sequently, the beam arrives at the screen at a higher vertical position than
previously (see figure G.2). The greater the voltage between the plates, the
greater the vertical deflection of the bright spot on the screen. If the polarity
of the voltage between the plates is reversed, the deflection of the light spot
is vertically downwards, i.e. reversed. The two horizontal plates, are there-
fore used to produce vertical deflection of the bright spot on the screen, i.e.
deflection in the Y direction. Similarly, the pair of vertically-arranged plates
may be used to produce deflection of the bright spot along the horizontal or
X direction on the screen. Because the beam of electrons has so very little
mass, it may be caused to move around the screen very rapidly by appropriate
rapidly changing voltages between the pairs of deflection plates .
...
~~~C.I~N___ : __ ........
BEAM -
VERTICAL
DEFLECTION
PLATES
SCREEN
Figure G.2 The deflecting action of the charged deflection plates on the beam of
negative electrons
APPENDIX G: CATHODE-RAY OSCILLOSCOPE 211
(a)
(b)
(c)
Figure G.3 Saw-tooth voltage variations with time, which are used to sweep the
electron beam horizontally across the viewing screen at different steady speeds. The
horizontal scale is then a time base with from (a) through (c) a decreasing time for the
sweep across the screen width
212 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
(b) The sensitivity of the vertical deflection. This setting controls the
amount of amplification applied to the time-varying voltage of interest before
it is applied to the vertical deflection plates.
(c) The brightness or luminance of the bright-spot display. This controls
the steady voltage of the control grid and thereby controls the amount of
electrons in the beam reaching the screen.
(d) The focus-control varies the voltages on the electrodes in the electron
gun and thereby helps to collimate the electron beam and to ensure that a
narrow beam reaches the screen.
(e) The triggering of the time-base. Sometimes, it is adequate for the
time-base voltages to be a free-running saw-tooth. But, often it is desirable
for the sweep of the saw-tooth of the time-base to start simultaneously with
portion of the voltage being examined. In such cases, instead of the saw-
tooth being free-running, it can be triggered to start when desired, i.e. when
the voltage of interest reaches a particular level or else by some other ex-
ternally-applied trigger signals.
Appendix H
STORAGE OSCILLOSCOPE
In the conventional oscilloscope, the phosphor chosen for coating the screen
usually has a short persistence. This means that the light from the phosphor
continues to be emitted for only a short period of time after the electrons
have stopped impinging on the phosphor. Longer persistence phosphors are
available and the effect with these phosphors is for the light to much more
gradually fade away, i.e. they possess a certain amount of short-term
memory. This memory can be greatly extended by use of storage oscillo-
scope tubes. Such a tube is shown schematically in figure H.!.
This oscilloscope tube differs from the conventional tube in two main
ways. First of aIL it possesses a coating of a dielectric or insulating material
inside the phosphor coating on the screen. When the electron beam is made
to move over the screen, the rapidly-moving high energy electrons in the
beam knock electrons off the insulator, leaving a pattern, or latent image,
of positively-charged regions on the insulator layer.
The second point of difference between the conventional and the storage
tube is the fact that the latter possesses extra electron guns. One of these
guns, when activated. is made to flood the full screen with medium energy
electrons. This means that it does not produce a collimated beam but rather
= DO
STORAGE MESH
Figure H.l The main elements in a storage oscilloscope tube, showing, in addition to
the features of a simple CRT, the storage and collector meshes or grids and the addi-
tional electron guns, the read flood gun and the erase flood gun
214 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
TV MONITOR
NECK
ELECTRON
GUN
The orderly sequence of the electron beam deflection, the so-cal1ed raster
scanning action , is illustrated in figure 1.2. The point of impact of the
electron beam with the screen, the bright spot, starts at the top left-hand
corner (as viewed from the front). As the spot is slowly deflected vertical1y
downwards by means of a slowly rising ramp current drive to the Y-coil, it
is simultaneously deflected horizontal1y to the right , by means of a more
rapidly-rising ramp current drive to the X-coil. As the spot thus describes a
line across the screen, the Z - or brightness - modulation signal increases or
decreases the luminance of the writing spot, in keeping with the image
information for that slice of the picture.
When the spot reaches the right-hand side of the picture the horizontal
deflection current abruptly drops to zero, the spot quickly flicks back to the
left-hand side of the picture to resume its smooth progress from left to right
along a second line. During the line fly-back shown in dotted lines in figure
I.2, the brightness is reduced below the visible so that no writing then occurs.
Continuing with this raster scanning action down to the bottom of the
picture or frame, there is produced on the screen a pattern of almost hori-
zontal writing lines and the brightness of the spot registered at each location
in the two dimensions is determined by the image information. In the normal
use of television, this image information comes from a camera but in ultra-
sound displays it comes from a scan converter.
~ -.-.:;....... -
-.: . . . - 3- ( -
.. - - --
----:3_ _...:._
- - - ',,-- -- -.......... . -. ..
...
,
... ~ "',
(a) (b)
Figure 1.2 The raster scanning action of the electron beam in a TV viewing tube . (a)
A simple sequential raster scan. (b) An interlaced raster scan
E E
······WHITE·········
~) (W
t t
Figure 1.3 The video voltage signal for one line of a raster scan in (a) a white-on-black
display and (b) a black-on-white display
it must be returned to the top left-hand corner, i.e. there must be a frame
fly-back at that juncture. During this fly-back also, writing must be sup-
pressed.
In practical high-resolution systems an interleaved, or interlaced, raster
scanning system is used as shown in figure I.2(b). In this type of scan an
initial frame is written with the lines more widely spaced and then during the
second half of the frame write period, the lines in between the first set are
written.
In most European countries each single partial pass through the field, or
frame, is repeated fifty times each second and, so, the complete interlaced
scan is repeated 25 times each second. In the European standard the inter-
laced scan has 625 lines. From this it can be seen that each second some
15625 lines are written or, as shown in figure 1.3, each line takes 64 flS. In
American systems, interlaced frames of 525 lines are repeated 30 times each
second.
When the bright-up pulse reaches the bottom right-hand corner of the
screen, the vertical deflection current drive drops to zero. The video signal
possesses coded frame synchronisation pulses which signal to the vertical or
frame drive to initiate a new frame from the top. Normally, the synchronisa-
tion signals are generated in the television camera electronics and the video,
or picture information, is generated by having the scene to be imaged pro-
duce a pattern of brightnesses in the light-sensitive surface in the camera. In
the ultrasound system all of these signals are generated in the scan converter,
the synchronisation pulses in the electronics and the video or picture signal
from the ultrasound image pattern stored in the memory.
The video signal of figure I.3(a) produces a white/grey image on a black
background. The inverted version of the same image consisting of black/grey
on a white background may be produced with an 'inverted video' signal such
as that of figure I.3(b). Inversion of the video signal may be readily achieved
electronically, for instance by using an inverting amplifier.
Appendix J
~ - ... . . - ~ . - . -
PUT OUTPUT
Figure J.t The data build-up on the scan converter storage screen (INPUT) occurs in
the fairly random fashion in which they are acquired during the scanning action of the
ultrasound probe. The read-out of the data (OUTPUT) is achieved in an orderly
raster pattern
APPENDIX J: ANALOGUE SCAN CONVERTERS 219
lSTORAGE SCREEN
0 :
b :
Do
b :
0 :
b :
b :
b :
b :
b :
b :
~b :\:~
0 :
"-
COLLECTOR GRI D
Figure J.2 The main features of a non-viewing analogue scan converter
There are a number of types of storage surface, and a commonly used one
is the barrier grid . This consists of a thin metal backing electrode coated
with a thin layer, in the form of a mosaic of small capacitor elements, of a
dielectric material. This is illustrated in figure J.3 . There can be up to 1000
by 1000 of these elements in the complete storage screen . Finally, there is a
metal grid interposed between the screen and the electron gun , the so-called
collector grid.
When the electron beam strikes the target , secondary electrons are knocked
0: DODD
tJ t DODD
O[ DODD
oi DO
(a)
0: (b)
o
~\ (.10kV)
TA~GET (.5V)
COLLECTOR (.120V)
Figure J.3 The details of the region near the storage screen of an analogue scan con-
verter, showing the final anode, the target or storage screen and the collector grid. The
actual storage screen is a two-dimensional array of elemental capacitors as in (b)
220 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
off the target. The voltage on the collector grid controls this secondary
emission as indicated in figure J.4. At low values of this voltage fewer
electrons are emitted than strike the target and so this becomes negatively
charged. At the critical voltage, there is no net storage of charge. At still
higher collector voltages, there are more electrons emitted than are incident
and so the target becomes positively charged. Furthermore over a range of
collector grid voltages, the amount of charge is approximately proportional
to the change in the grid voltage above Ec.
COLLECTOR
VOLTAGE
Figure J.4 The effect of the collector grid voltage on the production of secondary
electrons. R, the vertical ordinate, is the ratio of the number of electrons emitted by the
target to the number of electrons incident upon it
Initially, the electron beam is raster scanned over the target with the
screen voltage held below the critical voltage value. An even distribution of
charge is spread on all of the little capacitors making up the storage target.
For writing/storage, the screen voltage is raised above the critical voltage
so that when the electron beam strikes the surface, there is net emission. As
the writing electron beam moves over the surface, depending upon the
collector grid voltage (controlled now by the echo signal voltage), more or
less secondary emission happens and more or less positive charge is stored
on the elemental capacitors. The orientation of the writing line or vector on
the storage surface is controlled by the orientation of the probe which pro-
duces X and Y deflection signals for the scan converter. Consequently, the
pattern of stored charge is an analogue representation of the pattern of strong
and weak echoes produced as the ultrasound beam scans through the cross-
section of the tissues.
For reading/presenting the stored pattern for viewing on the TV monitor
the grid voltage is reduced to the critical value. The electron beam is raster
scanned over the storage target, and depending upon the charge stored on
the different elemental capacitors, more or less secondary electrons are
emitted to form the current through to the collector grid. Therefore, the
collector current depends directly on the charge stored on the screen and so
constitutes a video signal which can be used to produce the image on the TV
monitor.
APPENDIX J: ANALOGUE SCAN CONVERTERS 221
The single-ended scan converter can be used in one mode at a time and is
therefore suitable only for static B-mode scans. Even for these, it is not
totally satisfactory in that it takes some seconds to acquire a scan, and it is
desirable and necessary to view the scan as it is being acquired. But this scan
converter is not capable of performing in this way. Usually, a compromise
is used. What is done is to electronically switch between writing and reading
for equal intervals some ten times each frame. What results is a venetian
blind effect which allows a rough viewing of the image as it is being con-
structed. Thus, when the operator is doing the scanning, the scan converter
operates in this dual mode. When the operator is not moving the transducer
it operates in the read/view mode only.
There is one further mode of operation in the scan converter, the erase
mode, in which an even distribution of charge is established on all the
elemental capacitors. Erasing is achieved by setting the grid voltage below
the critical voltage and allowing the electron beam to raster scan over the
screen. Under these conditions the secondary emission of electrons is less
than the number of incident electrons and the capacitors charge up to a
steady voltage. The target is then essentially a tablet ready to receive another
array of charges, the analogues of the luminance pattern of the image.
fashion as for the single-ended device. The position of the writing vector is
controlled by the beam orientation. The locations where charges must be
stored are set by the pulse echo information while the amplitudes of the
echo signals determine the amounts of charge stored. The reading electron
beam is raster scanned over the target to generate the video signals for the
TV monitor.
Appendix K
DIGITAL COMPUTERS
CONTROL
UNIT
INPUT !-------.,t>I
OUTPUT
DEVICE DEVICE
ARITHMETIC
UNIT
Figure K.l The basic organisational and functional blocks of a digital computer
showing the interconnections between them
Decimal Binary
o o
1 1
2 10
3 11
4 100
5 101
6 110
7 111
8 1000
9 1001
10 1010
11 1011
12 1100
13 1101
14 1110
15 1111
16 10000
17 10001
18 10010
19 10011
20 10100
21 10101
22 10110
23 10111
24 11000
25 11001
26 11010
27 11011
28 11100
29 11101
30 11110
31 11111
32 100000
33 100001
(a)
t
(c)
Figure K.3 Comparison of the analogue and quantised digital versions of a voltage
signal
Appendix L
MAPPING
~:
y X
xx .XIX x~
IXIX
X
X
IX
IX
XIX IX IX ,IX IX
iXiX
unique address in the memory into which a number representing the ampli-
tude of the echo from the corresponding tissue location can be stored. This
number will also determine the luminance of the corresponding pixel in the
image. The more binary bits can be fitted into the address the wider the
dynamic range of the converter. Thus, 2 bits would accommodate 6 dB, 3
bits 9 dB, 4 bits 12 dB, 5 bits 15 dB, 6 bits 18 dB, 7 bits 21 dB, 8 bits 24 dB,
9 bits 27 dB and 10 bits 30 dB.
The scan converter must also be equipped with means of getting the
228 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
appropriate data into the correct addresses and of reading the data out and
converting them into analogue video signals for viewing on a TV monitor.
Figure L.2 is an overall scheme for achieving these tasks.
On the input or storing side, the A-mode echoes from a given beam orienta-
tion are sampled, digitised and held temporarily in a buffer memory. Simul-
taneously the set of memory addresses for that beam orientation must be
PROBE
COORDINATE
SIGNALS
TX
MASTER
CLOCK
TV
41 .:t
~
lJ.\i
I~
1/
(a)
(b)
1,6 2,6 3,5 ',5 5,5 6,' 7,' t (or U
Figure L.3 The assignment of quantised and digitised data from the echo train in an
A-mode scan, to memory locations appropriate to the probe vector and hence to pixels
in the image plane
The processes of reading and writing in the memory are not interactive
and can be done simultaneously. This scan converter is suitable therefore
for dynamic as well as static B-mode scanning.
However , to achieve a dynamic range even comparable to an analogue
scan converter - 6 bits and 512 x 512 pixels ~ .. requires some 1.6 million bits or
locations of memory, a large memory , and can consequently be expensive.
Among the special advantages of the digital scan converter are the possi-
bilities of digital processing of the signals either before the memory (pre-
processing) or after the memory and before display (post-processing). These
are capabilities that have not been much exploited as yet but some of the
potential processing steps are listed in figure LA. Among the pre-processing
steps possible are some now done in instruments by analogue methods -
setting suppressor and limiter levels, setting the time gain compensation
_. and some not now done such as corrections for the different sensitivities
of transducer with different focussing, or compensation for the possible
non-linear amplifier gain. Many of these processes could be done auto-
matically as determined by the operator through computer programmes.
Altl1Jth
230 BASIC PHYSICS AND TECHNOLOGY OF ULTRASOUND
(a)
Aldl DJJ
z
(b)
z
(C)
Ah n I!hTGC
llltr1--I--l1
ALt-LhJ1h
z
Ahi1Jtb
(d)
z
(e)
z
Figure L.4 A simplified representation of the preprocessing steps possible in a digital
scan converter. The quantised A-mode signal is shown in (a). The application of
suppression ofiow amplitude signals and ofiimiting or peak clipping of high amplitude
signals is indicated in (b). Implementing a given TGC is shown in (c). Modification of
the sensitivity to COrrect for beam focussing might result in the quantised signal of (d).
Removal of the effects of analogue TGC and correction for the different sensitivities
along the beam may result in the true amplitudes shown in (e)
grey scale. Thus, the effective gamma of the display can be chosen to match
the photographic film or to match the human vision.
Various spatial operations can also be implemented on the displayed
image by numerical manipulations on the data on the memory. Zooming--
magnifying or minifying a portion of the picture can be achieved by
assigning numbers to larger or smaller groups of pixel addresses in the
output buffer memory. Picture inversion from black on white to white on
black requires a subtraction operation on all pixel data. Any pixels which
may be empty due to an artifact while all surrounding pixels contain picture
information, may be filled with a number which is the average of the numbers
in the surrounding pixels.
Abrupt increases in image luminance can be smoothed out by averaging
the numbers stored in the adjacent pixel addresses. Likewise, increases or
decreases in luminances, stored as increasingly greater or smaller numbers in
the relevant memory locations, can be detected and enhanced. In this way
boundaries may be detected and highlighted. Furthermore the length of
such boundaries and the areas included within them may be computed.
Many of the procedures suggested in section 10.10 for tissue characterisa-
tion may also be implemented on the digital intermediate or stored image.
Index