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Evolution PART TWO
Evolution PART TWO
If heterozygote is favored with homozygous dominant then recessive genes can persist for a
long time due to the shielding effect form the heterozygote
Epistasis can cause unpredictable interactions that affect fitness(i.e.selection may occur until
another gene due to epistatsis gets to low and then selection stops and the lowering gene
increases)
Dominance and epistatsis can mask genetic variation. Dominance reduces correlation between
genotype and phenotype.
Jan30
Slide 7- selection is more effective on bottom because steeper slope, higher correlation between
offspring traits and parent traits.higher h, heritability.
Stronger appearance =stronger heritability
If heritability is low selection will work less because if less additive variation, lower heritability
which means lower correlation which means lower response rate/ selection has less effect
Example:maximizing agriculture
SLIDE 8
Answer1: because the number is increasing when we select for bristles over time.Responds to
selection over time
Answe 2: because when not selecting for bristle numbers the favored bristle number is less so
number of bristles drops.
SLIDE 11
Maturing at younger ages= smaller sizes. Energy now involved in reproduction. Stunted
population. (less large). When fishing stopped, body size went up( still matured young)
SLIDE 14
Organisms are continually adapting to a dynamic envirioment. When one thing fixes another
thing may worsen
FEB 1
Slide 8/populus. When a codominance factor is introduced. The shielding effect is turned off and
selection works more effectively against the new mutations. I.e. the little a mutations cant hide
behind the big A dominance in the heterozygotesThereofere q(weak allele) is smaller.
-Mutations are random. Eventually may stumble upon one that is strong and persists.
FEB 6-exam
FEB 8
Slide 8? Every population will be unique because of the random chance of which monomoprphic
variant will be present at equilibrium.
Bottleneck- natural colonization-small number of very specific founders not representative of all
types
Mutation with selection. If population is small enough/ if drift is the dominating force then
sometimes directional selection can succeed in fixating the most fit allele but sometimes drift will
succeed in eliminating the most fit allele.
Essentially the smaller the population size the more dynamic the standard selection graph will
be. The overall trend will be that of selection until the population is small enough that the
random chance of drift full eliminates an allele.likewise the strength of selection impacts this
dynamic equilibrium.
Slide 24-rate of evolution here = rate of mutation. Completely independent of population size.
Slide 30- If(s=selection coefficient) s > 1/2N selection dominates. If s <1/2N drift dominates.
Slide?- because…
FEB 13
Slide 12: if H is 0 then HWE and random mating is occurring. If H is 1 than all population is
inbreeding/non random mating
Dleterious dominant alleles persist shorter than deleterious recessive alleles because
deleterious recessive alleles have shielding from heterozygote
Slide16- outbreeding increases rate of hetrozygosity
Slide19- smaller Ne can increase chance of genetic drift
Slide 20- high varilability in population size=bottlenecks reducijng pop size
Slide 23- Ne is the real contributor to genetic drift.
Slide 25- any level of inbreeding will decrease the effective size which will decrease levels of
heterozygosit/ decrease genetic variation.
Slide 27-(not really related to slide in particular). Bottlenecks are special cases of genetic drift.
Very small populations are more likely to have inbreeding
Slide 28- good summary
Slide 39- bec smaller populations have a smaller chances for mutations.
Slide 40- sex in largepopulations allows fro recombinations and more adaptation
Slide 43- when there are more parasites/ pathogens than more sexual reproduction vs asexual