Antiretroviral drugs 2022/23
info
Drug names
Fixed dose combinations
 tripla (efavirenz +
A
emtricitabine + tenofovir DF)
Biktarvy (bictegravir + TAF +
emtricitabine)
Eviplera (rilpivirine +
emtricitabine + tenofovir DF)
Odefsey (rilpivirine +
emtricitabine + TAF)
Triumeq (dolutegravir +
abacavir + lamivudine)
Genvoya (elvitegravir +
cobicistat + emtricitabine + TAF)
Stribild (elvitegravir + dolutegravir (Tivicay) *
cobicistat + emtricitabine +
tenofovir DF)
Symtuza (darunavir + 
cobicistat + emtricitabine + TAF)
Delstrigo (doravirine + One tablet, once-daily, with or
lamivudine + tenofovir DF)
Dovato (dolutegravir + 
lamivudine)
Juluca (dolutegravir + 
rilpivirine)
Dual nukes: nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs)
t enofovir DF 300 mg +
emtricitabine 200 mg
(Truvada [pictured] or generic) ++
TAF (10 mg white or 25 mg blue) +
emtricitabine (200 mg), Descovy
abacavir 600 mg + lamivudine
300 mg (Kivexa or generic) ++
Injectable ART (cabotegravir/rilpivirine long-acting injections (CAB/RPV-LA) and single nukes
See back page for info on injectable ART. Also for single nukes (which are rarely used).
* Different doses or formulations might be used - always check doses with your pharmacist.
++
Generic versions might be a different colour and shape. § EU approval pending.
www.i-Base.
Recommended adult dose *
0 5 10 15 20 mm
Approximate to actual size.

One tablet, once-daily. Take at
night and not with a high fat meal.
See info on separate drugs.
One tablet, once-daily.
Take with or without food. 1
See info on separate drugs.

One tablet, once-daily, with food
(400 kcal). See separate drug info.

One tablet, once-daily, take with
food. See info on separate drugs.
One tablet, once-daily.
Take with or without food. 1
See info on separate drugs.
One tablet, once-daily.
Take with food. 1
See info on separate drugs.

One tablet, once-daily, take with
food. See info on separate drugs.
One tablet, once-daily, take with
food. See info on separate drugs.
without food. See info on each drug.
One tablet, once-daily, with or
without food. See info on each drug.
One tablet, once-daily, take with
food. See info on separate drugs.
One tablet, once-daily.
One tablet, once-daily.
One tablet, once-daily.
NNRTIs: non-nucleoside reverse transcriptase inhibitors (non-nukes)
Total daily pills
efavirenz 600 mg or 200 mg  x 600 tablet (or 3 x 200 caps) once-
1 1 tablet (or 3
(Sustiva, [pictured] or generic) ++ daily; at night, not with high fat meal. capsules)
1 nevirapine PR 400 mg (Viramune 1 x 400 mg once a day.
1 x 400 mg
[pictured] or generic ++ Take with or without food.
 x 100 mg OR 1 x 200 mg,
2
etravirine (100 mg
twice daily, take with food. 2 or 4
or 200 mg) (Intelence)
Dispersible in water.
1 rilpivirine  x 25 mg tablet, once-daily, take
1 1
(Edurant) with main meal (500 kcal).
1
doravirine  x 100 mg tablet, once-daily, take
1 1
(Pifeltro) with or without food.
INIs or INSTIs: integrase inhibitors
1 x 400 mg, twice-daily OR
raltegravir 400 mg (pink) &
2 x 600 mg tablet, once-daily. 2
600 mg (yellow) (Isentress)
Take with or without food.
 x 50 mg tablet, once-daily (or 1 x 50
1
mg twice -daily). With food if twice- 1 or 2
1
daily but with or without otherwise.
elvitegravir and bictegravir are only in combination pills – see Stribild, Genvoya and Biktarvy. 1
1
Injectable long-acting cabotegravir-LA (Vocabria) and rilpivirine - LA (Rekambys)
not to Two injections into muscle (in the
1 Cabotegravir + rilpivirine-LA. none
scale buttocks) every two months. Oral pills
(Vocabria + Rekambys)
might be used for the first month.
1
b/PI: boosted protease inhibitors
 x 300 mg cap + booster, once-daily.
1 1
1 atazanavir * (Reyataz) Take with food. 150 mg and 200 mg
(+ 1 booster)
capsules also available.
darunavir 600 mg 1 x 800 mg + booster once-daily (OR
1 or 2 (+ 1 or 2
(orange) & 800 mg 1 x 600 mg + 100 mg booster twice-
(red), (Prezista) * ++ boosters)
daily with resistance). Take with food.
1
atazanavir/cobicistat (Evotaz) 1 tablet, once-daily. Take with food. 1
1
darunavir/cobicistat (Rezolsta) 1 tablet, once-daily. Take with food. 1
1
PK (pharmacokinetic) boosters
cobicistat (/c)  50 mg tablet, once daily. Used to
1
depends on
(Tybost) boost atazanavir, darunavir and
boosted drug
elvitegravir.
ritonavir (/r) * ++
 00 mg tablets used at different doses
1 depends
(Norvir) to boost other PIs. on PI
 ARV chart
Drug names Recommended adult dose * Total daily pills

Entry inhibitors

2022/23
150 mg or 300 mg or 600 mg,
maraviroc * (Celsentri) as directed, depending 1 or 2 or 4
on other ARVs in the combination.

fostemsavir (Rukobia) 600 mg tablet, twice-daily. 2

June 2022

bNAbs (broadly neutralising monoclonal antibody) - an immune-based treatment

not to scale
will depend
150 mg/mL given as single
ibalizumab (Trogarzo) on other meds
IV infusion every two weeks.
being used

Single nukes (NRTIs)

lamivudine (3TC) ++ 1 x 300 mg (shown) or 2 x 150 mg, 1 if 300 mg
(Epivir [pictured] or generic ) (taken as a once-daily 2 if 150 mg
or twice-daily dose).
abacavir ++ 2 x 300 mg tablets (taken as a 2
(Ziagen [pictured] or generic) once-daily or twice-daily dose).

emtricitabine (FTC)
1 x 200 mg capsule, once-daily. 1
(Emtriva)

tenofovir DF * ++ 1 x 300 mg tablet, once-daily. 1

(Viread [pictured] or generic)

Notes These include zidovudine (AZT),

stavudine (d4T), zidovudine with
Paediatric formulations can sometimes
lamivudine, Trizivir, lopinavir/r,
be used in adults if larger pills are
fosamprenavir, tipranavir
difficult to swallow. Sometimes
and efuvirtide (T-20).
granules or liquids are available.
Pictures approximate to actual size.
Future drugs and combinations
Drugs that are used less If new drugs are approved during
2022/3, details will be posted online.
frequently
http://i-base.info/guides/category/arvs
Info is available online on older HIV
After drugs are approved it
drugs that are now rarely used.
usually takes the NHS 12 months
http://i-base.info/guides/category/arvs to decide on UK access.

i-base
A supplement to the i-Base
www.i-Base.info www.hivpa.org Introduction to ART