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Bernfort 2008
Bernfort 2008
REGULAR ARTICLE
Keywords Abstract
ADHD, Costs, Neuropsychiatric disorders, Outcome,
Aim: Attention deficit hyperactivity disorder (ADHD) and related disorders affect children’s ability to
Socio-economic perspective
function in school and other environments. Awareness has increased in recent years that the same
Correspondence
Dr. S. Nordfeldt, Division of Child and Adolescent problems often persist in adulthood. Based on previous studies, we aimed to outline and discuss a
Psychiatry, Department of Clinical and Experimental descriptive model for calculation of the societal costs associated with ADHD and related disorders.
Medicine, Faculty of Health Sciences, Linköping Methods: Following a literature review including childhood and adult studies, long-term outcomes of
University, S-581 85 Linköping, Sweden.
Tel: +46-13-222000 | Email: sam.nordfeldt@lio.se ADHD and associated societal costs were outlined in a simple model.
Received
Results: The literature concerning long-term consequences of ADHD and related disorders is scarce.
18 June 2007; revised 26 October 2007; accepted There is some evidence regarding educational level, psychosocial problems, substance abuse,
29 October 2007. psychiatric problems and risky behaviour. The problems are likely to affect employment status,
DOI:10.1111/j.1651-2227.2007.00611.x healthcare consumption, traffic and other accidents and criminality. A proposed model structure
includes persisting problems in adulthood, possible undesirable outcomes (and their probabilities)
and (lifetime) costs associated with these outcomes.
Conclusions: Existing literature supports the conclusion that ADHD and related disorders are associated with a
considerable societal burden. To estimate that burden with any accuracy, more detailed long-term data are
needed.
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ADHD from a socio-economic perspective Bernfort et al.
pounds was for lost productivity due to unemployment, marized in Table 1 and reviewed in the following section.
absence from work and premature mortality) (9). Less is Whether children or adults were studied is indicated where
known about the societal costs associated with ADHD. applicable.
The aim of this paper is to outline and discuss as a first step
a rough model for calculating the societal costs associated Psychosocial problems
with ADHD and related psychiatric disorders. Ideally, such Individuals with ADHD often have difficulties fitting in and
a model could be used in future analyses of cost-effectiveness functioning in social relations. These problems are most ob-
of treatments aimed at mitigating the symptoms of these dis- vious concerning relations and communication with others
orders. In order to create a model, possible long-term conse- in workplaces and within the family. The problems seem
quences must be identified. Therefore, the literature dealing to depend on emotional factors and communicative ability
with ADHD and outcomes in adulthood was reviewed. rather than a lack of understanding of how to behave accord-
ing to social norms (12). Problems with low self-esteem and a
METHODS limited circle of friends have been reported in children with
Based on findings from a previous literature study (10) and ADHD, and those problems also persist into young adult-
recent reviews covering long-term outcomes (5,11), the Med- hood (11).
line database was searched for the following terms: ADHD –
attention deficit hyperactivity disorder combined with costs Low educational level
(152 hits), psychiatric outcomes (67), psychosocial problems Symptoms associated with ADHD and related disorders in
(98), addiction (78), risk behaviour (29), health care con- childhood and adolescence often imply problems concern-
sumption (78), criminality (28), injuries (200) and life years ing schooling. These consist both of difficulties in acquir-
(103). Closer examination resulted in a smaller number of ing knowledge and lack of adaptability to school rules and
studies of real interest to this paper; childhood and adult routines.
studies dealing with long-term consequences of ADHD and Studies have shown that individuals with ADHD and re-
related disorders (compared to a control group) were in- lated disorders have on average a shorter education, fewer
cluded. Cost-effectiveness studies (of medication) not incor- higher degrees, poorer grades and more failed courses. This
porating long-term consequences were excluded. contributes to the fact that as adults they have employ-
Considering the limited long-term primary data, we settled ment of lower status compared to control groups (13,14).
on outlining a simple descriptive structure of the long-term In one study (14), 85 persons with ADHD (mean follow-up
process of ADHD and related disorders, and estimations of 17 years) and 73 controls were interviewed. Mean age was 24
potential cost savings were not performed. years in both groups. ADHD subjects had on average more
than 2 years less education than controls. Furthermore, 25%
RESULTS in the ADHD group did not finish high school (1% of con-
Difficulties and problems associated with ADHD trols), and only 15% in the ADHD group had a Bachelor’s
Some earlier studies of various long-term consequences as- degree (over 50% of controls). These results are supported
sociated with ADHD and related disorders are briefly sum- by other studies (5,11,13).
Psychosocial problems Lower self-rated social and emotional abilities. Evidently there are problems, but little calculable data
Lower self-esteem (11,12)
Low educational level Shorter education (on average about 2 years). Less high Evident problems and some quantified data exist
exams (13,14)
Substance abuse Earlier onset. More long-term abuse. Heavier drugs more Worse with ODD/CD. Well-documented problem
usual (13,15,20,22)
Psychiatric problems More often psychiatric disturbances. Increased risk of ASPD Results not all consistent. Increased risk of ASPD established
(25,29)
Risk behaviour More of traffic accidents and various violations (30) Evidence almost exclusively concerning traffic
Production loss Lower employment status. More often self-employed (14) A potentially large cost item, but data are scarce
Healthcare costs Costs doubled even when adjusted for psychiatric Some data exist. Significantly higher costs with ADHD
treatment (33)
Material costs No evidence found Costs should be higher with ADHD (accidents, material
damage)
Criminality More of arrests, convictions and incarcerations (36) Data difficult to use. Significantly increased risk with
ODD/CD
Life years lost Imperfect impulse control important predictor for No existing data, but probably a significant and important
premature death (5) cost item
Intangibles and other costs Data are scarce. Sleeping problems have been For instance impaired quality-of-life for patient and family
observed (40)
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Bernfort et al. ADHD from a socio-economic perspective
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ADHD from a socio-economic perspective Bernfort et al.
boys and girls as well as for different ages. One study found Intangibles and other costs
that costs for ADHD children were slightly, but not signifi- Intangible costs are hard to quantify and might be under-
cantly, higher than for children with asthma (34). stood as somewhat vague. Here, intangible costs mainly
A retrospective study found that even when controlling consist of impaired quality of life for persons affected by
for comorbidity, adult ADHD subjects compared to con- ADHD and related disorders. Other examples are suffer-
trols had significantly higher annual costs for outpatient care ing/impaired quality of life of others such as family members,
($ 3009 vs. $ 1492), inpatient care ($ 1259 vs. $ 514) and crime victims, etc.
drugs ($ 1673 vs. $ 1008) (32). Another study calculated the Impairments in quality of life in ADHD are the result of
costs per year for adult ADHD subjects at $ 4929 compared a complicated overall situation, but can be linked to psy-
to $ 1473 for controls (35). Family members of subjects with chosocial and psychiatric problems, sleeping problems and
ADHD have also been shown to consume more healthcare substance abuse. One study showed that irrespective of age,
resources (32,35). persons with ADHD had greater problems than controls in
falling asleep and sleeping all night, and that due in part to
this, they had more difficulty concentrating during the day-
Material costs
time (40). It has also been shown that family members of
Studies explicitly addressing the issue of material costs seem persons with ADHD consume significantly more healthcare
to be lacking. However, the risky behaviour often associated and have a significantly poorer economic situation in their
with ADHD subjects is likely to imply material costs result- households than other families (41,42).
ing from traffic accidents and various damages in workplaces Several studies of ADHD in childhood report a heavy
and other areas of society. This assumption is further en- emotional burden on the family. Life with an ADHD child
forced by the fact that substance abuse is more common in has been described as chaotic, filled with conflicts and ex-
ADHD subjects. As already mentioned, persons with ADHD hausting (43–45).
have a greater number of traffic accidents. The findings regarding long-term consequences are sum-
marized in Table 1.
Criminality
Individuals with ADHD and related disorders are over-
represented in crime statistics and among prison inmates, DISCUSSION
which is likely to result from risk behaviour, psychosocial The long-term outcomes associated with living with ADHD
problems and substance abuse. Societal costs of criminality and related disorders seem to imply heavy burdens both for
impact the law enforcement and judicial systems, the crimi- individuals and society. Therefore efforts to comprehend the
nal care system, and damage/suffering among crime victims. issue in a societal perspective are in great need. We found,
Hyperactive boys with CD (n = 89) were compared to however, that such information in the literature is rather
controls (n = 87) regarding criminality in adolescence and scarce and that it is hampered by methodological limitations.
young adulthood (36). Official records showed that hyper- First of all, the degree of later impairments found in cases
active boys with CD had significantly higher arrest rates in referred to clinics or included in follow-up studies may not
both adolescence (46% vs. 11%) and young adulthood (21% be representative for all cases in the population. Second,
vs. 1%). Others found that more individuals with ADHD, the methods used in the studies are mixed and are difficult
compared to controls, had been arrested (39% vs. 20%), to summarize. Moreover, increasing knowledge about the
convicted (28% vs. 11%) and incarcerated (9% vs. 1%) (37). developmental course of ADHD needs to be considered in
ADHD subjects had committed more crimes and had more prognostic models (46). The extent to which the reported
often been convicted several times. Similar results have been outcomes should be attributed to ADHD or to comorbid-
presented in other studies (38). ity, possibly with ADHD as a mediator, remains unclear.
A study of 100 adult prison inmates who had commit- For example, more information is needed in order to dis-
ted serious crimes showed that 63% fulfilled the diagnostic tinguish between the impact of ADHD and that of CD. The
criteria for CD. The study also found CD, but not ADHD, cost of antisocial behaviour has been investigated in a pi-
significantly associated with adult criminality (39). lot study in which detailed primary data were collected by
semi-structured interview (47). Within wide ranges, substan-
tial costs and other impacts related to CD were reported.
Life years lost Long-term outcome and costs in a societal perspective need
Life years lost can be difficult to quantify, but it is an im- more attention in clinical cohort studies of ADHD and re-
portant item in cost-of-illness analyses. Although no study lated disorders. As of today, it is clearly difficult to outline
showed that ADHD and related disorders were associated the life course of persons with ADHD in any detail.
with life years lost, we assume that this is the case. Stud- Health economic modelling is often used when clinical
ies have shown that poor impulse control per se is the sin- or other data are lacking, and it is therefore necessary to
gle most important factor in prediction of early death (5). apply well-grounded estimates of certain variables. Natu-
Substance abuse and psychiatric problems are factors that ral courses of chronic diseases are best simulated by use of
strengthen the assumption that ADHD and related disor- Markov models, in which a patient has certain probabilities
ders may be associated with life years lost. during each cycle (usually a year) of either remaining in the
242
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Bernfort et al. ADHD from a socio-economic perspective
Unwanted outcomes
/societal costs
Production loss
18 years Costsa
pa
Persistent severe Healthcare
problems (about 1%
Costsb
pb consumption
of the population)
3-5 years
• Psychosocial
pc Material damage Costsc
Diagnosis • Education
• Drug abuse pd
AD/HD Criminality
5-7% of the • Psychiatric Costsd
population • Risk behaviour pe
present state or moving to one of a number of other states. as in Table 2. An illustrative example was outlined showing
Data detailed enough to set up a Markov model were not that targeted preventive parental education could be given
available concerning ADHD. Therefore, while keeping the to 6900 parents at the 30-year cost (discount rate 2%) for
limitations in mind, a proposed rough model to describe the one single person with drug abuse – even without taking into
course of ADHD is discussed (Fig. 1). account any production losses.
In order to produce results from this model, one would Although very little specific hard data is available, it is rea-
need probabilities of different outcomes, and reliable pri- sonable to assume that the overall burden on society from
mary data for (lifetime) costs associated to the different ADHD and related disorders is considerable. In order to
outcomes. Such data are currently unavailable. Some data, estimate, at least roughly, the societal burden of these dis-
mainly American, exist concerning certain problems and orders, future research would need to answer the following
certain consequences. For instance, individuals with ADHD questions:
and related disorders as a group are over-represented among
1. How large are the proportions of men and women with
criminals have lower educational level and more often have
ADHD who experience different kinds of undesired life
lower-status employments. There are also strong indications
outcomes?
that ADHD subjects consume more healthcare resources,
2. How large are the lifetime costs associated with different
cause more material damage and they are at risk of losing
undesired life outcomes?
life years.
3. What is the influence on quality of life for individuals with
Our model was derived from a health-economic perspec-
ADHD and for family members?
tive and might perhaps seem simplistic. Future research is
4. Are there other consequences/undesired life outcomes
expected to add important knowledge regarding factors af-
that affect persons with ADHD to a greater extent than
fecting the outcomes. Clearly, a wider study covering the
they affect others?
impact of proposed mediating and moderating factors and
their interactive mechanisms in a development perspective In conclusion, although more detailed data on the proba-
would be valuable. bilities and costs of different outcomes are needed in order
Recently, some rough estimations of societal costs for psy- to calculate the burden and costs to society of ADHD and
chiatric disorders were presented in a Swedish governmental related disorders, we found compelling reasons for believing
agency report (48). Annual costs to society were suggested that the impact is considerable.
Table 2 Previously calculated rough examples of annual costs to society, excluding production losses due to inability to work (48)
Work-impeding psychosocial problems Eur 10 650 (SEK 100 000) Eur 254 350 (SEK 2 390 000)
Mental illness Eur 37 250 (SEK 350 000) Eur 916 100 (SEK 8 606 000)
Drug abuse Eur 66 000 (SEK 620 000) Eur 1 620 050 (SEK 15 215 000)
∗
Loss of production estimated at an additional Eur 702 650 (SEK 6 600 000) at 2% discount rate.
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ADHD from a socio-economic perspective Bernfort et al.
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