Pelvic organ prolapse is a benign common condition that
can lead to genital tract dysfunction and significantly
diminished quality of life. Approximately 3% of women complain of feeling a vaginal protrusion while up to 50% of women will be found to have prolapse on examination The lifetime risk of surgery for POP is 12–19%, with more than 300,000 women undergoing surgery a year in the USA. Approximately 8% of women in the UK report symptoms of prolapse . A 71-year-old woman presents to her gynecologist having noted a “ball” at her vaginal opening while showering. She denies bleeding and urinary incontinence, but does urinate frequently. Her past obstetrical and gynecological history is notable for three uncomplicated term VDs. She had normal monthly menses until menopause at age 50. Her surgical history is remarkable for tubal ligation following her third delivery. Pelvic exam is remarkable for protrusion of the anterior vaginal wall beyond the hymen while straining and descent of the cervix to near the hymen with straining. She has no palpable pelvic masses. Uterovaginal prolapse is caused by failure of the interaction between the levator ani muscles and the ligaments and fascia that support the pelvic organs. The levator ani muscles are puborectalis, pubococcygeus and iliococcygeus…. They are attached on each side of the pelvic side wall from the pubic ramus anteriorly (pubococcygeus), over the obturator internus fascia to the ischial spine to form a bowl-shaped muscle filling the pelvic outlet and supporting the pelvic organs There are three levels of supporting ligaments and fascia, which work together to provide a global and dynamic system to support the uterus, vagina and associated organs ▪ Level 1 (apical) support is provided by the uterosacral ligaments, which attach the cervix to the sacrum. ▪ Level 2 support is provided by the fascia that surrounds the vagina, both anteriorly and posteriorly, lying between the vagina and the bladder (pubocervical fascia) or rectum (rectovaginal fascia). ▪ Level 3 support is provided by the fascia of the posterior vagina, which is attached at its caudal end to the perineal body. ➢ Defects in level 1 support ► on examination by the descent of the uterus within the vagina. (manifest as vaginal vault prolapse after hysterectomy). ➢ Defects in level 2 support ► prolapse of the vaginal wall into the vaginal lumen (causing anterior or posterior vaginal prolapse and on examination, the affected vaginal wall will be seen bulging into the vagina). ➢ Defects of the perineal body ► development of lower posterior vaginal wall prolapse, but the loss of the perineal body increases the size of vaginal opening and therefore predisposes to anterior vaginal prolapse as well. KEY LEARNING POINTS ❖ The levator ani muscles support the pelvic organs and relieve excessive pressure from the ligaments and fascia. ❖ The uterosacral ligaments provide essential apical support (level 1 support). ❖ Vaginal fascia supports the vagina (level 2 support). ❖ The perineal body is very important in supporting the lower vagina (level 3 support). Risk Factors Associated with Pelvic Organ Prolapse Pregnancy Vaginal childbirth ( Multiparity, Forceps delivery, Perineal trauma, Long labour, Birthweight >4 kg. Menopause ( Aging, Hypoestrogenism) Chronically increased intraabdominal pressure (Chronic obstructive pulmonary disease, Constipation, Obesity), Occupation Pelvic floor trauma( Genetic factors, Race, Connective tissue disorders) Spina bifida POP can cause symptoms directly due to the prolapsed organ or indirectly due to organ dysfunction secondary to displacement from the anatomical position. Signs: include descent of one or more o the following: the anterior vaginal wall, posterior vaginal wall, uterus and cervix, vaginal apex, or the perineum Symptoms likely to correlate with POP: ➢ Bulge (vaginal bulging, pelvic pressure, and splinting or digitation)- Splinting is manual bolstering of the prolapse to improve symptoms, where as digitation aids stool evacuation ➢ Fullness. ➢ Dragging and deterioration with activity (sensation of vaginal bulge, heaviness or a visible protrusion at or beyond the introitus) Symptoms relieved by rest(lower abdominal or back pain, or a dragging discomfort relieved by lying or sitting) Pelvic organ prolapse is descent of the anterior vaginal wall, posterior vaginal wall, uterus (cervix), the vaginal apex after hysterectomy, rectum, or the perineum, alone or in combination. The history should elicit the presenting symptom(s) and severity, and include questions if there is any coexisting urinary, faecal or sexual symptoms and note should be made of whether it occurs at patient straining or at rest and whether traction has been applied. Symptoms Associated with Pelvic Organ Prolapse Symptoms unlikely to correlate with POP ➢ Backache. ➢ Pain. ➢ Urinary and/or bowel dysfunction. ➢ Sexual dysfunction. Prolapse is described in three stages of descent: • Stage I where the prolapse does not reach the hymen. • Stage II where the prolapse reaches the hymen. • Stage III when the prolapse is mostly or wholly outside the hymen. When the uterus prolapses wholly outside this is termed procidentia. In women who have undergone hysterectomy, the vaginal vault can prolapse Another commonly used POP staging system is the `` Baden–Walker Halfway Scoring System`` :
0 Normal position for each respective site
1 Descent halfway to the hymen 2 Descent to the hymen 3 Descent halfway past the hymen 4 Maximum possible descent for each site For the pelvic examination the women should ideally be examined in the dorsal lithotomy position with Valsalva. This has been shown to be as effective as an examination in the standing position. The most important assessment is whether the vaginal prolapse reaches to, or beyond, the hymen. Finally, it is important to assess whether the perineal body is intact or has become attenuated, resulting in an enlarged vaginal opening. For women with symptoms of pressure or vaginal bulge only, there is rarely a need to arrange any investigations, other than those relating to anesthetic preassessment Lower urinary tract symptoms should be evaluated independently with urinalysis. Urodynamic testing may be helpful where there are significant urinary symptoms. functional tests of the lower bowel may include endoanal ultrasound to check for anal a sphincter defects, rectal manometry, flexible sigmoidoscopy and a defaecating proctogram Conservative: ➢ Conservative treatment It is always preferable and should not proceed with a surgical procedure without first offering a trial of conservative treatment. ➢ It includes pelvic floor muscle exercises and the use of supportive vaginal pessaries. A course of supervised pelvic floor exercises will reduce the symptoms of prolapse and for women who are keen to avoid surgical treatment. ➢ Lifestyle advice such as weight loss and smoking cessation ➢ it is unlikely to be helpful for women whose prolapse is beyond the vaginal introitus. ➢ Pessary use can be very effective at relieving symptoms and has the advantage of avoiding surgery, specially in the medically unfit and elderly. ➢ Ring pessaries need an intact perineal body while Shelf pessaries, Gelhorn pessaries are useful for women with deficient perineal bodies. ➢ It is usual practice to replace a pessary every 6 months and to examine the patient for signs of vaginal ulceration. ➢ Complications are uncommon and usually minor (bleeding, discharge, pessary incarceration ``requiring general anesthesia to remove``, and rare cases of rectovaginal or vesicovaginal fistula) Surgical management: Principles of POP surgery: ➢ Remove/reduce the vaginal bulge. ➢ Restore the ligament/tissue supports to the apex, anterior and posterior vagina. ➢ Replace associated organs in their correct positions. ➢ Retain sufficient vaginal length and width to allow intercourse. ➢ Restore the perineal body. ➢ Correct or prevent urinary incontinence. ➢ Correct or prevent fecal incontinence. ➢ Correct obstructed defecation. Vaginal repair using mesh improves the anatomical outcome and reduces the risk of recurrent prolapse. Mesh repair carries the risk of later erosion and need for removal and only be considered for women with recurrent vaginal prolapse. Surgery should be reserved for patients who have at least stage 2 POP on examination and have bothersome symptoms using vaginal or abdominal approaches(open or minimal access surgery (MAS) undertaken either laparoscopically or robotically Surgical options Restorative :Vaginal : ●● Anterior colporrhaphy. ●● Posterior colporrhaphy. ●● Vaginal hysterectomy. ●● Sacrospinous fixation. ●● Sacrospinous hysteropexy. ●● Uterosacral plication. Abdominal : ●● Sacrocolpopexy (open/laparoscopic/robotic). ●● Sacrohysteropexy (open/laparoscopic/robotic). Obliterative ●● Colpocleisis. Vaginal closure