COLEGIO NUEVA YORK

EXPERIMENTAL SCIENCE DEPARTMENT

BIOLOGY MYP 8TH GRADE 1st TERM
TEACHER: EDISON ALFONSO

Endocrine System Workshop

Name: __________________________ Class: ________ Date: _______________

REFLECTING ON THE IMPACT OF SCIENCE

GRADE 1 2 3 4 5 6 7
MARKS 0-3 4-5 6-7 8-9 10-11 12-13 14-15

KNOWING AND UNDERSTANDING

GRADE 1 2 3 4 5 6 7
MARKS 0-3 4-7 8-11 12-14 15-17 18-20 21

PROCESSING AND EVALUATING

GRADE 1 2 3 4 5 6 7
MARKS 0-2 3-5 6-8 9-11 12-14 15-17 18-19

REFLECTING ON THE IMPACT OF SCIENCE – 15 MARKS

Read the following passage and answer the questions.

Medical Breakthroughs in the Endocrine System

Over the past century, numerous medical breakthroughs have revolutionized our understanding of the
endocrine system, leading to significant advancements in healthcare and enhancing our ability to diagnose
and treat various conditions. Let's explore some key breakthroughs that have shaped the field.

Hormone Discovery: One of the early breakthroughs occurred in the 1920s with the discovery of insulin
by Sir Frederick Banting and Charles Best. This hormone, produced by the pancreas, plays a crucial role
in regulating blood sugar levels. The isolation and use of insulin transformed the lives of individuals with
diabetes, allowing them to manage their condition effectively.

Thyroid Hormones and Iodine Deficiency: In the mid-20th century, scientists uncovered the importance
of iodine in thyroid function. The development of iodized salt helped address widespread iodine deficiency,
preventing thyroid-related disorders. This breakthrough significantly improved public health globally.

In-Vitro Fertilization (IVF): Advancements in reproductive endocrinology marked a groundbreaking era in

the late 20th century. The development of in-vitro fertilization (IVF) by Dr. Robert Edwards and Dr. Patrick
Steptoe in 1978 allowed couples struggling with infertility to conceive successfully. This breakthrough
opened new possibilities for family planning.

Growth Hormone Therapy: The synthesis of growth hormone in the laboratory during the 1980s
revolutionized the treatment of growth disorders in children. Recombinant DNA technology enabled the
production of synthetic growth hormone, providing a safe and effective solution for individuals with growth
hormone deficiencies.

Adapted from: Endocrine Society (2024). Endocrinology Field. Retrieved from:

https://www.endocrine.org/our-community/advancing-endocrinology-and-public-health/field-of-
endocrinology

1. How has the isolation and use of insulin impacted individuals with diabetes? [3 marks]

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2. How did the development of iodized salt contribute to global public health? [3 marks]

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CNY- Biology – Junior- 8- Edison Alfonso, 100 copias, doble cara, tamaño oficio.
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3. What significant possibilities did IVF open up for couples struggling with infertility? [3
marks]

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4. How has recombinant DNA technology impacted the treatment of growth disorders in
children? [3 marks]

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5. Consider the overall impact of these endocrine breakthroughs on healthcare and society.
How do these advancements reflect the intersection of science and human well-being? [3
marks]

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KNOWING AND UNDERSTANDING – 21 MARKS

6. Positive vs. Negative Feedback: Identify if the following are describing positive feedback or
negative feedback. [ 7 marks]

A. ________________________ regulated by opposing hormones. One hormone may raise the level of a
particular chemical or action while the other hormone lowers the level of the chemical or action.

B. ________________________ the rise in blood glucose levels triggers the pancreatic release of insulin.
Insulin causes blood glucose levels to drop, which signals the pancreas to stop producing insulin.

C. ________________________ the release of the hormone or the activity causes an increase in the
production of the hormone.

D. ________________________ used to maintain homeostasis.

E. ________________________ effects of the stimuli are designed to amplify the results.

F. ________________________ most common form of feedback in the endocrine system

G. ________________________ inhibitory and stabilizing

7. Matching the word with their respectively definition. [ 14 marks]

1) Calcium homeostasis.
_____ endocrine system
_____ endocrine glands 2) female reproductive glands

3) Responsible for carbohydrate metabolism.

_____ target tissue
4) Glands that send secretions called hormones to
_____ hormones specific sites.
 5) responsible for fight / flight
_____ pituitary gland
6) specialized tissues that are affected by hormones
_____ thyroid gland
7) male reproductive glands
_____ parathyroid gland
8) produced by the ovaries
_____ oxytocin
9) regulates metabolism and uses iodine
_____ pancreas
10) often called the master gland
_____ adrenal glands
11) made up of three groups: Amines, Proteins, and steroids
_____ ovaries
12) produced by the posterior pituitary gland causes contractions
_____ testes of the uterus and stimulates the release of milk

13) the other regulating system of the body

_____ progesterone
_____ testosterone 14) development of secondary sex characteristics

PROCESSING AND EVALUATING – 19 MARKS

Use next information to answer the following questions.

What is the A1C test?

The A1C test is a blood test that provides information about your average levels of blood glucose, also
called blood sugar, over the past 3 months. The A1C test can be used to diagnose type 2 diabetes and
prediabetes.1 The A1C test is also the primary test used for diabetes management.

Blood Glucose Measurements Compared with A1C Measurements over 4 Days

Figure 1. Blood glucose (mg/dL) measurements were taken four times per day (fasting or pre-
breakfast, pre-lunch, pre-dinner, and bedtime).

A1C results and what the numbers mean.

Source:https://www.niddk.nih.gov/health-information/diagnostic-tests/a1c-test

*Any test used to diagnose diabetes requires confirmation with a second measurement, unless there are
clear symptoms of diabetes.

8. State a hypothesis that was evaluated by the researchers. Remember the structure: if….
Then … because…. [ 1 mark]

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 9. See the figure 1 and state the variables: [ 3 marks]

Independent variable: _____________________________________________

Dependent variable: _______________________________________________

Control variable: _________________________________________________

10. How does the A1C measurement of 7.0 percent correlate with the blood glucose levels
obtained through self-monitoring four times a day over a 4-day period? [3 marks]

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11. Are there noticeable fluctuations in blood glucose levels throughout the 4-day period of self-
monitoring? [3 marks]
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12. How do the self-monitored blood glucose levels compare to the recommended A1C target
of 7.0 percent? [3 marks]
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13. Can patterns or trends be identified in the blood glucose levels over the 4-day period? [3
marks]
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14. According to A1C range from figure 1 and table, would the individual be diagnosed with
prediabetes? [3 marks]
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References
National Institute of Diabetes and Digestive and Kidneys Diseases (n/d) . The A1C Test & Diabetes.
Retrieved from: https://www.niddk.nih.gov/health-information/diagnostic-tests/a1c-test